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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for AACACUG

Z-value: 1.85

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miRNA associated with seed AACACUG

NamemiRBASE accession
hsa-miR-141-3p
MIMAT0000432
hsa-miR-200a-3p
MIMAT0000682

Activity profile of AACACUG motif

Sorted Z-values of AACACUG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_98605902 1.46 ENST00000460070.1
ENST00000481455.1
ENST00000261574.5
ENST00000493281.1
ENST00000463157.1
ENST00000471898.1
ENST00000489058.1
ENST00000481689.1
IPO5
importin 5
chr9_-_6015607 1.26 ENST00000259569.5
RANBP6
RAN binding protein 6
chr3_-_112360116 1.18 ENST00000206423.3
ENST00000439685.2
CCDC80
coiled-coil domain containing 80
chr1_-_200379180 1.13 ENST00000294740.3
ZNF281
zinc finger protein 281
chr11_+_86748863 1.04 ENST00000340353.7
TMEM135
transmembrane protein 135
chr3_+_187930719 1.03 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr18_+_29171689 1.02 ENST00000237014.3
TTR
transthyretin
chr11_-_105892937 0.98 ENST00000301919.4
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
MSANTD4
Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
chr14_-_57735528 0.92 ENST00000340918.7
ENST00000413566.2
EXOC5
exocyst complex component 5
chr6_-_18265050 0.92 ENST00000397239.3
DEK
DEK oncogene
chr7_-_156803329 0.91 ENST00000252971.6
MNX1
motor neuron and pancreas homeobox 1
chr14_-_38064198 0.89 ENST00000250448.2
FOXA1
forkhead box A1
chr5_+_82767284 0.87 ENST00000265077.3
VCAN
versican
chr17_-_63052929 0.87 ENST00000439174.2
GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr10_-_62704005 0.84 ENST00000337910.5
RHOBTB1
Rho-related BTB domain containing 1
chr10_+_89622870 0.80 ENST00000371953.3
PTEN
phosphatase and tensin homolog
chr6_+_64281906 0.77 ENST00000370651.3
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr10_-_81205373 0.76 ENST00000372336.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr9_+_118916082 0.76 ENST00000328252.3
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr9_-_123476719 0.73 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr15_+_77712993 0.72 ENST00000336216.4
ENST00000381714.3
ENST00000558651.1
HMG20A
high mobility group 20A
chr6_+_1610681 0.72 ENST00000380874.2
FOXC1
forkhead box C1
chr1_-_150208291 0.71 ENST00000533654.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr15_+_52311398 0.71 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr8_+_55370487 0.70 ENST00000297316.4
SOX17
SRY (sex determining region Y)-box 17
chr15_+_57210818 0.69 ENST00000438423.2
ENST00000267811.5
ENST00000452095.2
ENST00000559609.1
ENST00000333725.5
TCF12
transcription factor 12
chr4_-_83719983 0.68 ENST00000319540.4
SCD5
stearoyl-CoA desaturase 5
chr1_+_93913713 0.67 ENST00000604705.1
ENST00000370253.2
FNBP1L
formin binding protein 1-like
chr10_+_112631547 0.65 ENST00000280154.7
ENST00000393104.2
PDCD4
programmed cell death 4 (neoplastic transformation inhibitor)
chr15_-_25684110 0.64 ENST00000232165.3
UBE3A
ubiquitin protein ligase E3A
chr4_-_76598296 0.63 ENST00000395719.3
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr7_+_99613195 0.63 ENST00000324306.6
ZKSCAN1
zinc finger with KRAB and SCAN domains 1
chr10_+_14920843 0.62 ENST00000433779.1
ENST00000378325.3
ENST00000354919.6
ENST00000313519.5
ENST00000420416.1
SUV39H2
suppressor of variegation 3-9 homolog 2 (Drosophila)
chr14_+_36295504 0.62 ENST00000216807.7
BRMS1L
breast cancer metastasis-suppressor 1-like
chr17_+_4901199 0.61 ENST00000320785.5
ENST00000574165.1
KIF1C
kinesin family member 1C
chr1_+_51701924 0.60 ENST00000242719.3
RNF11
ring finger protein 11
chr1_+_28586006 0.59 ENST00000253063.3
SESN2
sestrin 2
chr3_+_113465866 0.59 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr3_-_24536253 0.58 ENST00000428492.1
ENST00000396671.2
ENST00000431815.1
ENST00000418247.1
ENST00000416420.1
ENST00000356447.4
THRB
thyroid hormone receptor, beta
chr9_+_116638562 0.58 ENST00000374126.5
ENST00000288466.7
ZNF618
zinc finger protein 618
chr21_-_15755446 0.57 ENST00000544452.1
ENST00000285667.3
HSPA13
heat shock protein 70kDa family, member 13
chr10_+_119000604 0.57 ENST00000298472.5
SLC18A2
solute carrier family 18 (vesicular monoamine transporter), member 2
chr2_-_134326009 0.56 ENST00000409261.1
ENST00000409213.1
NCKAP5
NCK-associated protein 5
chr7_-_108096822 0.55 ENST00000379028.3
ENST00000413765.2
ENST00000379022.4
NRCAM
neuronal cell adhesion molecule
chr11_+_32914579 0.55 ENST00000399302.2
QSER1
glutamine and serine rich 1
chrX_+_21857717 0.54 ENST00000379484.5
MBTPS2
membrane-bound transcription factor peptidase, site 2
chr10_+_69644404 0.53 ENST00000212015.6
SIRT1
sirtuin 1
chr7_-_75988321 0.52 ENST00000307630.3
YWHAG
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
chr1_+_40723779 0.52 ENST00000372759.3
ZMPSTE24
zinc metallopeptidase STE24
chr2_-_152684977 0.51 ENST00000428992.2
ENST00000295087.8
ARL5A
ADP-ribosylation factor-like 5A
chr14_-_100070363 0.51 ENST00000380243.4
CCDC85C
coiled-coil domain containing 85C
chr1_+_95582881 0.50 ENST00000370203.4
ENST00000456991.1
TMEM56
transmembrane protein 56
chr17_-_1928621 0.50 ENST00000331238.6
RTN4RL1
reticulon 4 receptor-like 1
chr20_+_33814457 0.49 ENST00000246186.6
MMP24
matrix metallopeptidase 24 (membrane-inserted)
chr12_+_41086297 0.49 ENST00000551295.2
CNTN1
contactin 1
chr13_+_42846272 0.49 ENST00000025301.2
AKAP11
A kinase (PRKA) anchor protein 11
chr9_-_74980113 0.48 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
ZFAND5
zinc finger, AN1-type domain 5
chr17_-_46671323 0.47 ENST00000239151.5
HOXB5
homeobox B5
chr13_+_80055284 0.47 ENST00000218652.7
NDFIP2
Nedd4 family interacting protein 2
chr1_+_61547894 0.46 ENST00000403491.3
NFIA
nuclear factor I/A
chr14_-_30396948 0.46 ENST00000331968.5
PRKD1
protein kinase D1
chr1_+_211433275 0.46 ENST00000367005.4
RCOR3
REST corepressor 3
chr14_-_90085458 0.45 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3
forkhead box N3
chr1_-_211752073 0.45 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr12_-_104532062 0.44 ENST00000240055.3
NFYB
nuclear transcription factor Y, beta
chr4_-_100815525 0.43 ENST00000226522.8
ENST00000499666.2
LAMTOR3
late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
chr1_-_85514120 0.42 ENST00000370589.2
ENST00000341115.4
ENST00000370587.1
MCOLN3
mucolipin 3
chr3_+_152017181 0.42 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
MBNL1
muscleblind-like splicing regulator 1
chr5_-_43313574 0.42 ENST00000325110.6
ENST00000433297.2
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr3_+_179065474 0.42 ENST00000471841.1
ENST00000280653.7
MFN1
mitofusin 1
chr12_-_76478686 0.42 ENST00000261182.8
NAP1L1
nucleosome assembly protein 1-like 1
chr1_+_218519577 0.39 ENST00000366930.4
ENST00000366929.4
TGFB2
transforming growth factor, beta 2
chr10_+_111767720 0.39 ENST00000356080.4
ENST00000277900.8
ADD3
adducin 3 (gamma)
chr1_+_200708671 0.39 ENST00000358823.2
CAMSAP2
calmodulin regulated spectrin-associated protein family, member 2
chr6_-_10415470 0.38 ENST00000379604.2
ENST00000379613.3
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr13_-_110438914 0.38 ENST00000375856.3
IRS2
insulin receptor substrate 2
chr9_-_136933134 0.38 ENST00000303407.7
BRD3
bromodomain containing 3
chr19_-_41196534 0.37 ENST00000252891.4
NUMBL
numb homolog (Drosophila)-like
chr17_-_41856305 0.37 ENST00000397937.2
ENST00000226004.3
DUSP3
dual specificity phosphatase 3
chr3_+_33318914 0.37 ENST00000484457.1
ENST00000538892.1
ENST00000538181.1
ENST00000446237.3
ENST00000507198.1
FBXL2
F-box and leucine-rich repeat protein 2
chr10_+_93558069 0.36 ENST00000371627.4
TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr6_-_122792919 0.36 ENST00000339697.4
SERINC1
serine incorporator 1
chr2_+_60983361 0.36 ENST00000238714.3
PAPOLG
poly(A) polymerase gamma
chr7_-_92463210 0.36 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr16_-_30798492 0.35 ENST00000262525.4
ZNF629
zinc finger protein 629
chrX_-_131352152 0.35 ENST00000342983.2
RAP2C
RAP2C, member of RAS oncogene family
chr4_-_140098339 0.35 ENST00000394235.2
ELF2
E74-like factor 2 (ets domain transcription factor)
chr5_+_78908233 0.35 ENST00000453514.1
ENST00000423041.2
ENST00000504233.1
ENST00000428308.2
PAPD4
PAP associated domain containing 4
chr4_-_184580353 0.35 ENST00000326397.5
RWDD4
RWD domain containing 4
chr8_-_95961578 0.34 ENST00000448464.2
ENST00000342697.4
TP53INP1
tumor protein p53 inducible nuclear protein 1
chr5_-_142783175 0.33 ENST00000231509.3
ENST00000394464.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr20_+_277737 0.33 ENST00000382352.3
ZCCHC3
zinc finger, CCHC domain containing 3
chr5_-_32444828 0.33 ENST00000265069.8
ZFR
zinc finger RNA binding protein
chr3_+_25469724 0.32 ENST00000437042.2
RARB
retinoic acid receptor, beta
chr6_+_155054459 0.32 ENST00000367178.3
ENST00000417268.1
ENST00000367186.4
SCAF8
SR-related CTD-associated factor 8
chr17_-_49198216 0.32 ENST00000262013.7
ENST00000357122.4
SPAG9
sperm associated antigen 9
chr1_-_84464780 0.32 ENST00000260505.8
TTLL7
tubulin tyrosine ligase-like family, member 7
chr1_-_204380919 0.31 ENST00000367188.4
PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr3_+_141205852 0.31 ENST00000286364.3
ENST00000452898.1
RASA2
RAS p21 protein activator 2
chr8_+_48920960 0.31 ENST00000523111.2
ENST00000523432.1
ENST00000521346.1
ENST00000517630.1
UBE2V2
ubiquitin-conjugating enzyme E2 variant 2
chr13_-_73356009 0.31 ENST00000377780.4
ENST00000377767.4
DIS3
DIS3 mitotic control homolog (S. cerevisiae)
chr15_-_37390482 0.31 ENST00000559085.1
ENST00000397624.3
MEIS2
Meis homeobox 2
chr3_-_195808952 0.31 ENST00000540528.1
ENST00000392396.3
ENST00000535031.1
ENST00000420415.1
TFRC
transferrin receptor
chr17_+_28705921 0.30 ENST00000225719.4
CPD
carboxypeptidase D
chr6_+_107811162 0.30 ENST00000317357.5
SOBP
sine oculis binding protein homolog (Drosophila)
chr7_+_129710350 0.30 ENST00000335420.5
ENST00000463413.1
KLHDC10
kelch domain containing 10
chr3_+_112709804 0.30 ENST00000383677.3
GTPBP8
GTP-binding protein 8 (putative)
chr2_+_102508955 0.30 ENST00000414004.2
FLJ20373
FLJ20373
chr5_+_172483347 0.30 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
CREBRF
CREB3 regulatory factor
chr4_+_144257915 0.30 ENST00000262995.4
GAB1
GRB2-associated binding protein 1
chr7_-_82073109 0.29 ENST00000356860.3
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr7_+_35840542 0.29 ENST00000435235.1
ENST00000399034.2
ENST00000350320.6
ENST00000469679.2
SEPT7
septin 7
chr3_-_125313934 0.29 ENST00000296220.5
OSBPL11
oxysterol binding protein-like 11
chr11_-_118550375 0.29 ENST00000525958.1
ENST00000264029.4
ENST00000397925.1
ENST00000529101.1
TREH
trehalase (brush-border membrane glycoprotein)
chr7_-_135662056 0.28 ENST00000393085.3
ENST00000435723.1
MTPN
myotrophin
chr1_+_84543734 0.28 ENST00000370689.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr2_+_169312350 0.28 ENST00000305747.6
CERS6
ceramide synthase 6
chr14_-_31676964 0.28 ENST00000553700.1
HECTD1
HECT domain containing E3 ubiquitin protein ligase 1
chr5_+_118407053 0.27 ENST00000311085.8
ENST00000539542.1
DMXL1
Dmx-like 1
chr1_-_166845515 0.27 ENST00000367874.4
TADA1
transcriptional adaptor 1
chr13_+_93879085 0.27 ENST00000377047.4
GPC6
glypican 6
chr16_+_53088885 0.27 ENST00000566029.1
ENST00000447540.1
CHD9
chromodomain helicase DNA binding protein 9
chr17_-_8534067 0.26 ENST00000360416.3
ENST00000269243.4
MYH10
myosin, heavy chain 10, non-muscle
chr7_-_6388537 0.26 ENST00000313324.4
ENST00000530143.1
FAM220A
family with sequence similarity 220, member A
chr17_-_74137374 0.26 ENST00000322957.6
FOXJ1
forkhead box J1
chr12_+_125478241 0.26 ENST00000341446.8
BRI3BP
BRI3 binding protein
chr6_+_10556215 0.26 ENST00000316170.3
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr4_-_105416039 0.26 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr15_-_72612470 0.26 ENST00000287202.5
CELF6
CUGBP, Elav-like family member 6
chr10_-_71930222 0.25 ENST00000458634.2
ENST00000373239.2
ENST00000373242.2
ENST00000373241.4
SAR1A
SAR1 homolog A (S. cerevisiae)
chr14_+_97263641 0.25 ENST00000216639.3
VRK1
vaccinia related kinase 1
chr2_-_175499294 0.25 ENST00000392547.2
WIPF1
WAS/WASL interacting protein family, member 1
chr3_+_152552685 0.25 ENST00000305097.3
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr1_+_93544791 0.25 ENST00000545708.1
ENST00000540243.1
ENST00000370298.4
MTF2
metal response element binding transcription factor 2
chr15_-_51058005 0.25 ENST00000261854.5
SPPL2A
signal peptide peptidase like 2A
chr17_+_38278530 0.24 ENST00000398532.4
MSL1
male-specific lethal 1 homolog (Drosophila)
chr4_-_40631859 0.24 ENST00000295971.7
ENST00000319592.4
RBM47
RNA binding motif protein 47
chr4_-_100871506 0.24 ENST00000296417.5
H2AFZ
H2A histone family, member Z
chr2_+_138721850 0.24 ENST00000329366.4
ENST00000280097.3
HNMT
histamine N-methyltransferase
chr8_-_55014415 0.24 ENST00000522007.1
ENST00000521898.1
ENST00000518546.1
ENST00000316963.3
LYPLA1
lysophospholipase I
chr1_-_159832438 0.24 ENST00000368100.1
VSIG8
V-set and immunoglobulin domain containing 8
chr17_-_19771216 0.24 ENST00000395544.4
ULK2
unc-51 like autophagy activating kinase 2
chr5_+_145826867 0.24 ENST00000296702.5
ENST00000394421.2
TCERG1
transcription elongation regulator 1
chr17_-_4269768 0.23 ENST00000396981.2
UBE2G1
ubiquitin-conjugating enzyme E2G 1
chr16_-_46865047 0.23 ENST00000394806.2
C16orf87
chromosome 16 open reading frame 87
chrX_+_16804544 0.23 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr11_-_129872712 0.23 ENST00000358825.5
ENST00000360871.3
ENST00000528746.1
PRDM10
PR domain containing 10
chr2_-_167232484 0.23 ENST00000375387.4
ENST00000303354.6
ENST00000409672.1
SCN9A
sodium channel, voltage-gated, type IX, alpha subunit
chr11_+_61159832 0.23 ENST00000334888.5
ENST00000398979.3
TMEM216
transmembrane protein 216
chr17_-_58603568 0.23 ENST00000083182.3
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr20_-_57617831 0.23 ENST00000371033.5
ENST00000355937.4
SLMO2
slowmo homolog 2 (Drosophila)
chr10_+_65281123 0.22 ENST00000298249.4
ENST00000373758.4
REEP3
receptor accessory protein 3
chr17_-_46178527 0.22 ENST00000393408.3
CBX1
chromobox homolog 1
chr8_+_26149007 0.22 ENST00000380737.3
ENST00000524169.1
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr6_+_127439749 0.22 ENST00000356698.4
RSPO3
R-spondin 3
chr10_-_33623564 0.22 ENST00000374875.1
ENST00000374822.4
NRP1
neuropilin 1
chr2_+_178257372 0.22 ENST00000264167.4
ENST00000409888.1
AGPS
alkylglycerone phosphate synthase
chr5_+_56205081 0.22 ENST00000285947.2
ENST00000541720.1
SETD9
SET domain containing 9
chr9_+_32384617 0.21 ENST00000379923.1
ENST00000309951.6
ENST00000541043.1
ACO1
aconitase 1, soluble
chrX_+_118370211 0.21 ENST00000217971.7
PGRMC1
progesterone receptor membrane component 1
chr17_+_56160768 0.21 ENST00000579991.2
DYNLL2
dynein, light chain, LC8-type 2
chr2_-_37899323 0.21 ENST00000295324.3
ENST00000457889.1
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr1_-_205180664 0.21 ENST00000367161.3
ENST00000367162.3
ENST00000367160.4
DSTYK
dual serine/threonine and tyrosine protein kinase
chr2_+_10861775 0.20 ENST00000272238.4
ENST00000381661.3
ATP6V1C2
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2
chr3_+_73045936 0.20 ENST00000356692.5
ENST00000488810.1
ENST00000394284.3
ENST00000295862.9
ENST00000495566.1
PPP4R2
protein phosphatase 4, regulatory subunit 2
chr3_-_88108192 0.20 ENST00000309534.6
CGGBP1
CGG triplet repeat binding protein 1
chr3_+_19988566 0.20 ENST00000273047.4
RAB5A
RAB5A, member RAS oncogene family
chr7_-_11871815 0.20 ENST00000423059.4
THSD7A
thrombospondin, type I, domain containing 7A
chr2_+_30369807 0.20 ENST00000379520.3
ENST00000379519.3
ENST00000261353.4
YPEL5
yippee-like 5 (Drosophila)
chr13_-_30881621 0.20 ENST00000380615.3
KATNAL1
katanin p60 subunit A-like 1
chr8_+_124780672 0.20 ENST00000521166.1
ENST00000334705.7
FAM91A1
family with sequence similarity 91, member A1
chr4_-_68566832 0.19 ENST00000420827.2
ENST00000322244.5
UBA6
ubiquitin-like modifier activating enzyme 6
chr2_+_64681219 0.19 ENST00000238875.5
LGALSL
lectin, galactoside-binding-like
chr12_-_46766577 0.19 ENST00000256689.5
SLC38A2
solute carrier family 38, member 2
chr12_+_68042495 0.19 ENST00000344096.3
DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr18_+_19321281 0.18 ENST00000261537.6
MIB1
mindbomb E3 ubiquitin protein ligase 1
chr11_-_117186946 0.18 ENST00000313005.6
ENST00000528053.1
BACE1
beta-site APP-cleaving enzyme 1
chr16_+_19125252 0.18 ENST00000566735.1
ENST00000381440.3
ITPRIPL2
inositol 1,4,5-trisphosphate receptor interacting protein-like 2
chr6_+_170102210 0.18 ENST00000439249.1
ENST00000332290.2
C6orf120
chromosome 6 open reading frame 120
chr1_-_243418344 0.18 ENST00000366542.1
CEP170
centrosomal protein 170kDa
chr13_+_78109884 0.18 ENST00000377246.3
ENST00000349847.3
SCEL
sciellin
chr16_+_21610797 0.18 ENST00000358154.3
METTL9
methyltransferase like 9
chr10_-_94333784 0.17 ENST00000265986.6
IDE
insulin-degrading enzyme
chr2_-_24149977 0.17 ENST00000238789.5
ATAD2B
ATPase family, AAA domain containing 2B
chr2_+_135676381 0.17 ENST00000537343.1
ENST00000295238.6
ENST00000264157.5
CCNT2
cyclin T2
chr10_+_60936347 0.17 ENST00000373880.4
PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr10_-_65225722 0.17 ENST00000399251.1
JMJD1C
jumonji domain containing 1C
chr5_-_172198190 0.17 ENST00000239223.3
DUSP1
dual specificity phosphatase 1
chr21_+_34697209 0.17 ENST00000270139.3
IFNAR1
interferon (alpha, beta and omega) receptor 1
chr1_+_168195229 0.17 ENST00000271375.4
ENST00000367825.3
SFT2D2
SFT2 domain containing 2
chr14_-_64010046 0.17 ENST00000337537.3
PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr17_-_49337392 0.17 ENST00000376381.2
ENST00000586178.1
MBTD1
mbt domain containing 1
chr14_-_35182994 0.17 ENST00000341223.3
CFL2
cofilin 2 (muscle)
chr1_+_22379120 0.17 ENST00000400259.1
ENST00000344548.3
CDC42
cell division cycle 42
chr20_+_43104508 0.17 ENST00000262605.4
ENST00000372904.3
TTPAL
tocopherol (alpha) transfer protein-like
chr20_-_22565101 0.16 ENST00000419308.2
FOXA2
forkhead box A2
chr5_-_132113036 0.16 ENST00000378706.1
SEPT8
septin 8
chr3_-_136471204 0.16 ENST00000480733.1
ENST00000383202.2
ENST00000236698.5
ENST00000434713.2
STAG1
stromal antigen 1
chr11_+_101981169 0.16 ENST00000526343.1
ENST00000282441.5
ENST00000537274.1
ENST00000345877.2
YAP1
Yes-associated protein 1
chr5_-_132073210 0.16 ENST00000378735.1
ENST00000378746.4
KIF3A
kinesin family member 3A

Network of associatons between targets according to the STRING database.

First level regulatory network of AACACUG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.3 1.0 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.3 0.9 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.2 0.7 GO:0042662 negative regulation of mesodermal cell fate specification(GO:0042662) regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796) gall bladder development(GO:0061010)
0.2 0.7 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.2 0.8 GO:1903984 negative regulation of ribosome biogenesis(GO:0090071) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.2 0.6 GO:0042137 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) sequestering of neurotransmitter(GO:0042137)
0.2 0.7 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.2 0.5 GO:1990619 histone H3-K9 deacetylation(GO:1990619)
0.2 0.5 GO:0030327 prenylated protein catabolic process(GO:0030327) CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.2 2.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.6 GO:0008050 female courtship behavior(GO:0008050)
0.1 0.4 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 0.4 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.3 GO:0002663 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.1 1.0 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.4 GO:0021622 optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.1 0.4 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.1 0.4 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.9 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.3 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.2 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.4 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.2 GO:0019085 early viral transcription(GO:0019085)
0.1 0.6 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.5 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.1 0.6 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.1 0.2 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1 0.9 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 0.3 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.1 GO:0035283 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.9 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.3 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.3 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.1 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.2 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.2 GO:0038189 vestibulocochlear nerve structural organization(GO:0021649) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) positive regulation of retinal ganglion cell axon guidance(GO:1902336) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.2 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.5 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.3 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.3 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.3 GO:0006983 ER overload response(GO:0006983)
0.0 1.2 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 1.2 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.8 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.3 GO:0071484 cellular response to light intensity(GO:0071484)
0.0 0.6 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.3 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.3 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.1 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.0 0.7 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.2 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.6 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.2 GO:0021764 amygdala development(GO:0021764)
0.0 0.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.7 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.4 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.3 GO:0097338 response to clozapine(GO:0097338)
0.0 1.0 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.2 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0098904 regulation of AV node cell action potential(GO:0098904)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0006789 bilirubin conjugation(GO:0006789)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.2 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.6 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.2 GO:1904688 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) regulation of rRNA processing(GO:2000232) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.0 0.7 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.1 GO:0034093 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.5 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 1.1 GO:0033572 transferrin transport(GO:0033572)
0.0 0.1 GO:0002249 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.3 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.0 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0 0.2 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:2000690 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.2 GO:0032328 alanine transport(GO:0032328)
0.0 0.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 0.0 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 1.0 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.2 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.0 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.7 GO:0043486 histone exchange(GO:0043486)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:1901094 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.0 0.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.1 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.1 0.3 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 0.1 GO:0071203 WASH complex(GO:0071203)
0.1 0.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.3 GO:0043291 RAVE complex(GO:0043291)
0.1 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 0.6 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 1.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.3 GO:0097513 myosin II filament(GO:0097513)
0.0 0.6 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.8 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.7 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.4 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.4 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 1.0 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.6 GO:0043194 axon initial segment(GO:0043194)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.5 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.7 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.3 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.7 GO:0005643 nuclear pore(GO:0005643)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 1.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.2 0.5 GO:0032129 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.1 0.4 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.5 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 0.4 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.9 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 1.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.4 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.3 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.3 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.1 0.6 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974) S-adenosyl-L-methionine binding(GO:1904047)
0.1 0.6 GO:0070728 leucine binding(GO:0070728)
0.1 0.7 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.2 GO:0051538 iron-responsive element binding(GO:0030350) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 3.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.3 GO:0097677 STAT family protein binding(GO:0097677)
0.1 0.3 GO:0031493 nucleosomal histone binding(GO:0031493)
0.1 0.3 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.6 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.1 0.7 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.2 GO:0031626 beta-endorphin binding(GO:0031626)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.2 GO:0019961 interferon binding(GO:0019961)
0.1 0.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.3 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 1.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.9 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.7 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.8 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.4 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 2.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.0 GO:0050733 RS domain binding(GO:0050733)
0.0 0.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 1.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.0 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.7 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 3.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.4 PID FOXO PATHWAY FoxO family signaling
0.0 0.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.8 PID IGF1 PATHWAY IGF1 pathway
0.0 0.9 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.0 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.0 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 1.1 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 1.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG