A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
Name | miRBASE accession |
---|---|
hsa-miR-29a-3p
|
MIMAT0000086 |
hsa-miR-29b-3p
|
MIMAT0000100 |
hsa-miR-29c-3p
|
MIMAT0000681 |
Promoter | Log-likelihood | Transcript | Gene | Gene Info |
---|---|---|---|---|
chr8_-_23261589 | 0.68 |
ENST00000524168.1
ENST00000523833.2 ENST00000519243.1 ENST00000389131.3 |
LOXL2
|
lysyl oxidase-like 2 |
chr8_-_139926236 | 0.35 |
ENST00000303045.6
ENST00000435777.1 |
COL22A1
|
collagen, type XXII, alpha 1 |
chr5_-_121413974 | 0.32 |
ENST00000231004.4
|
LOX
|
lysyl oxidase |
chr5_-_90679145 | 0.31 |
ENST00000265138.3
|
ARRDC3
|
arrestin domain containing 3 |
chr5_-_141704566 | 0.31 |
ENST00000344120.4
ENST00000434127.2 |
SPRY4
|
sprouty homolog 4 (Drosophila) |
chr10_+_101419187 | 0.28 |
ENST00000370489.4
|
ENTPD7
|
ectonucleoside triphosphate diphosphohydrolase 7 |
chr14_+_103058948 | 0.26 |
ENST00000262241.6
|
RCOR1
|
REST corepressor 1 |
chr10_+_75757863 | 0.26 |
ENST00000372755.3
ENST00000211998.4 ENST00000417648.2 |
VCL
|
vinculin |
chr6_-_43596899 | 0.26 |
ENST00000307126.5
ENST00000452781.1 |
GTPBP2
|
GTP binding protein 2 |
chr5_-_78281603 | 0.26 |
ENST00000264914.4
|
ARSB
|
arylsulfatase B |
chr4_-_54930790 | 0.25 |
ENST00000263921.3
|
CHIC2
|
cysteine-rich hydrophobic domain 2 |
chr8_-_23712312 | 0.25 |
ENST00000290271.2
|
STC1
|
stanniocalcin 1 |
chr5_-_111093406 | 0.25 |
ENST00000379671.3
|
NREP
|
neuronal regeneration related protein |
chr3_-_120170052 | 0.24 |
ENST00000295633.3
|
FSTL1
|
follistatin-like 1 |
chr20_-_23402028 | 0.24 |
ENST00000398425.3
ENST00000432543.2 ENST00000377026.4 |
NAPB
|
N-ethylmaleimide-sensitive factor attachment protein, beta |
chr11_-_124806297 | 0.23 |
ENST00000298251.4
|
HEPACAM
|
hepatic and glial cell adhesion molecule |
chr16_+_55512742 | 0.23 |
ENST00000568715.1
ENST00000219070.4 |
MMP2
|
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) |
chr4_+_39699664 | 0.22 |
ENST00000261427.5
ENST00000510934.1 ENST00000295963.6 |
UBE2K
|
ubiquitin-conjugating enzyme E2K |
chr3_-_190040223 | 0.22 |
ENST00000295522.3
|
CLDN1
|
claudin 1 |
chr1_-_244013384 | 0.22 |
ENST00000366539.1
|
AKT3
|
v-akt murine thymoma viral oncogene homolog 3 |
chr1_+_87170247 | 0.22 |
ENST00000370558.4
|
SH3GLB1
|
SH3-domain GRB2-like endophilin B1 |
chr10_+_82213904 | 0.21 |
ENST00000429989.3
|
TSPAN14
|
tetraspanin 14 |
chr9_+_129622904 | 0.21 |
ENST00000319119.4
|
ZBTB34
|
zinc finger and BTB domain containing 34 |
chr9_+_135037334 | 0.21 |
ENST00000393229.3
ENST00000360670.3 ENST00000393228.4 ENST00000372179.3 |
NTNG2
|
netrin G2 |
chr6_+_138188551 | 0.21 |
ENST00000237289.4
ENST00000433680.1 |
TNFAIP3
|
tumor necrosis factor, alpha-induced protein 3 |
chr3_-_64673289 | 0.21 |
ENST00000295903.4
|
ADAMTS9
|
ADAM metallopeptidase with thrombospondin type 1 motif, 9 |
chr1_-_27816556 | 0.20 |
ENST00000536657.1
|
WASF2
|
WAS protein family, member 2 |
chr14_+_55034599 | 0.20 |
ENST00000392067.3
ENST00000357634.3 |
SAMD4A
|
sterile alpha motif domain containing 4A |
chr2_-_162931052 | 0.20 |
ENST00000360534.3
|
DPP4
|
dipeptidyl-peptidase 4 |
chr16_+_69599861 | 0.19 |
ENST00000354436.2
|
NFAT5
|
nuclear factor of activated T-cells 5, tonicity-responsive |
chr12_-_48744554 | 0.19 |
ENST00000544117.2
ENST00000548932.1 ENST00000549125.1 ENST00000301042.3 ENST00000547026.1 |
ZNF641
|
zinc finger protein 641 |
chr11_+_60691924 | 0.19 |
ENST00000544065.1
ENST00000453848.2 ENST00000005286.4 |
TMEM132A
|
transmembrane protein 132A |
chr4_-_17783135 | 0.19 |
ENST00000265018.3
|
FAM184B
|
family with sequence similarity 184, member B |
chr10_+_80828774 | 0.19 |
ENST00000334512.5
|
ZMIZ1
|
zinc finger, MIZ-type containing 1 |
chr2_-_179315786 | 0.18 |
ENST00000457633.1
ENST00000438687.3 ENST00000325748.4 |
PRKRA
|
protein kinase, interferon-inducible double stranded RNA dependent activator |
chr6_-_30043539 | 0.18 |
ENST00000376751.3
ENST00000244360.6 |
RNF39
|
ring finger protein 39 |
chr17_+_26662730 | 0.18 |
ENST00000226225.2
|
TNFAIP1
|
tumor necrosis factor, alpha-induced protein 1 (endothelial) |
chr1_+_151030234 | 0.18 |
ENST00000368921.3
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
chr3_-_48632593 | 0.18 |
ENST00000454817.1
ENST00000328333.8 |
COL7A1
|
collagen, type VII, alpha 1 |
chr2_-_1748214 | 0.18 |
ENST00000433670.1
ENST00000425171.1 ENST00000252804.4 |
PXDN
|
peroxidasin homolog (Drosophila) |
chr9_+_78505581 | 0.17 |
ENST00000376767.3
ENST00000376752.4 |
PCSK5
|
proprotein convertase subtilisin/kexin type 5 |
chr1_-_46598284 | 0.17 |
ENST00000423209.1
ENST00000262741.5 |
PIK3R3
|
phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
chr1_-_3447967 | 0.17 |
ENST00000294599.4
|
MEGF6
|
multiple EGF-like-domains 6 |
chr8_-_110988070 | 0.17 |
ENST00000524391.1
|
KCNV1
|
potassium channel, subfamily V, member 1 |
chrX_+_73641286 | 0.17 |
ENST00000587091.1
|
SLC16A2
|
solute carrier family 16, member 2 (thyroid hormone transporter) |
chr6_-_134639180 | 0.17 |
ENST00000367858.5
|
SGK1
|
serum/glucocorticoid regulated kinase 1 |
chr3_-_133614597 | 0.16 |
ENST00000285208.4
ENST00000460865.3 |
RAB6B
|
RAB6B, member RAS oncogene family |
chr1_-_113498943 | 0.16 |
ENST00000369626.3
|
SLC16A1
|
solute carrier family 16 (monocarboxylate transporter), member 1 |
chr14_+_64932210 | 0.16 |
ENST00000394718.4
|
AKAP5
|
A kinase (PRKA) anchor protein 5 |
chrX_+_95939711 | 0.16 |
ENST00000373049.4
ENST00000324765.8 |
DIAPH2
|
diaphanous-related formin 2 |
chr16_+_69221028 | 0.16 |
ENST00000336278.4
|
SNTB2
|
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) |
chr4_-_10458982 | 0.16 |
ENST00000326756.3
|
ZNF518B
|
zinc finger protein 518B |
chr10_+_105726862 | 0.16 |
ENST00000335753.4
ENST00000369755.3 |
SLK
|
STE20-like kinase |
chrX_+_41192595 | 0.16 |
ENST00000399959.2
|
DDX3X
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
chr1_+_40627038 | 0.16 |
ENST00000372771.4
|
RLF
|
rearranged L-myc fusion |
chr7_+_106809406 | 0.16 |
ENST00000468410.1
ENST00000478930.1 ENST00000464009.1 ENST00000222574.4 |
HBP1
|
HMG-box transcription factor 1 |
chr5_+_96271141 | 0.15 |
ENST00000231368.5
|
LNPEP
|
leucyl/cystinyl aminopeptidase |
chr10_+_43633914 | 0.15 |
ENST00000374466.3
ENST00000374464.1 |
CSGALNACT2
|
chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
chr1_-_150849208 | 0.15 |
ENST00000358595.5
|
ARNT
|
aryl hydrocarbon receptor nuclear translocator |
chr3_+_137906109 | 0.15 |
ENST00000481646.1
ENST00000469044.1 ENST00000491704.1 ENST00000461600.1 |
ARMC8
|
armadillo repeat containing 8 |
chr9_-_127905736 | 0.15 |
ENST00000336505.6
ENST00000373549.4 |
SCAI
|
suppressor of cancer cell invasion |
chr5_-_89770582 | 0.15 |
ENST00000316610.6
|
MBLAC2
|
metallo-beta-lactamase domain containing 2 |
chr20_+_46130601 | 0.15 |
ENST00000341724.6
|
NCOA3
|
nuclear receptor coactivator 3 |
chr11_-_118661828 | 0.15 |
ENST00000264018.4
|
DDX6
|
DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
chr13_+_50018402 | 0.15 |
ENST00000354234.4
|
SETDB2
|
SET domain, bifurcated 2 |
chr12_+_112563335 | 0.15 |
ENST00000549358.1
ENST00000257604.5 ENST00000548092.1 ENST00000552896.1 |
TRAFD1
|
TRAF-type zinc finger domain containing 1 |
chr20_+_55204351 | 0.15 |
ENST00000201031.2
|
TFAP2C
|
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
chr4_+_166794383 | 0.14 |
ENST00000061240.2
ENST00000507499.1 |
TLL1
|
tolloid-like 1 |
chr5_-_107006596 | 0.14 |
ENST00000333274.6
|
EFNA5
|
ephrin-A5 |
chr5_-_157002775 | 0.14 |
ENST00000257527.4
|
ADAM19
|
ADAM metallopeptidase domain 19 |
chr2_-_240322643 | 0.14 |
ENST00000345617.3
|
HDAC4
|
histone deacetylase 4 |
chr17_+_72209653 | 0.14 |
ENST00000269346.4
|
TTYH2
|
tweety family member 2 |
chr2_+_227700652 | 0.14 |
ENST00000341329.3
ENST00000392062.2 ENST00000437454.1 ENST00000443477.1 ENST00000423616.1 ENST00000448992.1 |
RHBDD1
|
rhomboid domain containing 1 |
chr13_+_41363581 | 0.14 |
ENST00000338625.4
|
SLC25A15
|
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 |
chr14_-_95786200 | 0.14 |
ENST00000298912.4
|
CLMN
|
calmin (calponin-like, transmembrane) |
chr9_+_112810878 | 0.14 |
ENST00000434623.2
ENST00000374525.1 |
AKAP2
|
A kinase (PRKA) anchor protein 2 |
chr9_+_107526443 | 0.14 |
ENST00000374762.3
|
NIPSNAP3B
|
nipsnap homolog 3B (C. elegans) |
chr3_-_138553594 | 0.14 |
ENST00000477593.1
ENST00000483968.1 |
PIK3CB
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta |
chr1_+_16174280 | 0.14 |
ENST00000375759.3
|
SPEN
|
spen family transcriptional repressor |
chrX_+_115567767 | 0.14 |
ENST00000371900.4
|
SLC6A14
|
solute carrier family 6 (amino acid transporter), member 14 |
chr5_+_138678131 | 0.14 |
ENST00000394795.2
ENST00000510080.1 |
PAIP2
|
poly(A) binding protein interacting protein 2 |
chr13_+_110959598 | 0.14 |
ENST00000360467.5
|
COL4A2
|
collagen, type IV, alpha 2 |
chr17_-_6459768 | 0.14 |
ENST00000421306.3
|
PITPNM3
|
PITPNM family member 3 |
chr2_-_61697862 | 0.13 |
ENST00000398571.2
|
USP34
|
ubiquitin specific peptidase 34 |
chr4_-_80994210 | 0.13 |
ENST00000403729.2
|
ANTXR2
|
anthrax toxin receptor 2 |
chr2_-_37193606 | 0.13 |
ENST00000379213.2
ENST00000263918.4 |
STRN
|
striatin, calmodulin binding protein |
chr10_+_111967345 | 0.13 |
ENST00000332674.5
ENST00000453116.1 |
MXI1
|
MAX interactor 1, dimerization protein |
chr1_+_182992545 | 0.13 |
ENST00000258341.4
|
LAMC1
|
laminin, gamma 1 (formerly LAMB2) |
chr17_-_62658186 | 0.13 |
ENST00000262435.9
|
SMURF2
|
SMAD specific E3 ubiquitin protein ligase 2 |
chr11_-_61348576 | 0.13 |
ENST00000263846.4
|
SYT7
|
synaptotagmin VII |
chr1_+_24882560 | 0.13 |
ENST00000374392.2
|
NCMAP
|
noncompact myelin associated protein |
chr14_-_45431091 | 0.13 |
ENST00000579157.1
ENST00000396128.4 ENST00000556500.1 |
KLHL28
|
kelch-like family member 28 |
chr16_+_66914264 | 0.13 |
ENST00000311765.2
ENST00000568869.1 ENST00000561704.1 ENST00000568398.1 ENST00000566776.1 |
PDP2
|
pyruvate dehyrogenase phosphatase catalytic subunit 2 |
chr5_+_151151471 | 0.13 |
ENST00000394123.3
ENST00000543466.1 |
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1 |
chr4_+_113066552 | 0.12 |
ENST00000309733.5
|
C4orf32
|
chromosome 4 open reading frame 32 |
chr6_+_28317685 | 0.12 |
ENST00000252211.2
ENST00000341464.5 ENST00000377255.3 |
ZKSCAN3
|
zinc finger with KRAB and SCAN domains 3 |
chr9_-_37465396 | 0.12 |
ENST00000307750.4
|
ZBTB5
|
zinc finger and BTB domain containing 5 |
chr15_+_98503922 | 0.12 |
ENST00000268042.6
|
ARRDC4
|
arrestin domain containing 4 |
chr2_+_70142189 | 0.12 |
ENST00000264444.2
|
MXD1
|
MAX dimerization protein 1 |
chr2_-_74405929 | 0.12 |
ENST00000396049.4
|
MOB1A
|
MOB kinase activator 1A |
chr18_+_8609402 | 0.12 |
ENST00000329286.6
|
RAB12
|
RAB12, member RAS oncogene family |
chr1_-_35325400 | 0.12 |
ENST00000521580.2
|
SMIM12
|
small integral membrane protein 12 |
chr16_-_23160591 | 0.12 |
ENST00000219689.7
|
USP31
|
ubiquitin specific peptidase 31 |
chr7_-_129592700 | 0.12 |
ENST00000472396.1
ENST00000355621.3 |
UBE2H
|
ubiquitin-conjugating enzyme E2H |
chr1_+_110693103 | 0.12 |
ENST00000331565.4
|
SLC6A17
|
solute carrier family 6 (neutral amino acid transporter), member 17 |
chr3_+_142720366 | 0.11 |
ENST00000493782.1
ENST00000397933.2 ENST00000473835.2 ENST00000493598.2 |
U2SURP
|
U2 snRNP-associated SURP domain containing |
chr11_-_65149422 | 0.11 |
ENST00000526432.1
ENST00000527174.1 |
SLC25A45
|
solute carrier family 25, member 45 |
chrX_+_70364667 | 0.11 |
ENST00000536169.1
ENST00000395855.2 ENST00000374051.3 ENST00000358741.3 |
NLGN3
|
neuroligin 3 |
chr16_+_66461175 | 0.11 |
ENST00000536005.2
ENST00000299694.8 ENST00000561796.1 |
BEAN1
|
brain expressed, associated with NEDD4, 1 |
chr12_-_69326940 | 0.11 |
ENST00000549781.1
ENST00000548262.1 ENST00000551568.1 ENST00000548954.1 |
CPM
|
carboxypeptidase M |
chr15_-_48937982 | 0.11 |
ENST00000316623.5
|
FBN1
|
fibrillin 1 |
chr3_+_190231840 | 0.11 |
ENST00000072516.3
ENST00000443369.2 ENST00000412504.2 ENST00000439062.1 ENST00000447382.1 ENST00000422625.1 ENST00000422485.1 |
IL1RAP
|
interleukin 1 receptor accessory protein |
chr15_+_78730531 | 0.11 |
ENST00000258886.8
|
IREB2
|
iron-responsive element binding protein 2 |
chr3_-_149470229 | 0.11 |
ENST00000473414.1
|
COMMD2
|
COMM domain containing 2 |
chr11_+_74459876 | 0.11 |
ENST00000299563.4
|
RNF169
|
ring finger protein 169 |
chr9_-_130693048 | 0.11 |
ENST00000388747.4
|
PIP5KL1
|
phosphatidylinositol-4-phosphate 5-kinase-like 1 |
chr5_-_146833485 | 0.11 |
ENST00000398514.3
|
DPYSL3
|
dihydropyrimidinase-like 3 |
chr1_+_22379120 | 0.11 |
ENST00000400259.1
ENST00000344548.3 |
CDC42
|
cell division cycle 42 |
chr9_+_137533615 | 0.11 |
ENST00000371817.3
|
COL5A1
|
collagen, type V, alpha 1 |
chr8_-_119124045 | 0.11 |
ENST00000378204.2
|
EXT1
|
exostosin glycosyltransferase 1 |
chr4_+_128886532 | 0.11 |
ENST00000444616.1
ENST00000388795.5 |
C4orf29
|
chromosome 4 open reading frame 29 |
chr5_+_78532003 | 0.10 |
ENST00000396137.4
|
JMY
|
junction mediating and regulatory protein, p53 cofactor |
chr10_-_33246722 | 0.10 |
ENST00000437302.1
ENST00000396033.2 |
ITGB1
|
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
chr9_+_112542572 | 0.10 |
ENST00000374530.3
|
PALM2-AKAP2
|
PALM2-AKAP2 readthrough |
chr19_-_47249679 | 0.10 |
ENST00000263280.6
|
STRN4
|
striatin, calmodulin binding protein 4 |
chr8_+_11141925 | 0.10 |
ENST00000221086.3
|
MTMR9
|
myotubularin related protein 9 |
chr19_-_913160 | 0.10 |
ENST00000361574.5
ENST00000587975.1 |
R3HDM4
|
R3H domain containing 4 |
chr7_-_75368248 | 0.10 |
ENST00000434438.2
ENST00000336926.6 |
HIP1
|
huntingtin interacting protein 1 |
chr12_-_8025442 | 0.10 |
ENST00000340749.5
ENST00000535295.1 ENST00000539234.1 |
SLC2A14
|
solute carrier family 2 (facilitated glucose transporter), member 14 |
chr1_-_120612240 | 0.10 |
ENST00000256646.2
|
NOTCH2
|
notch 2 |
chr6_-_24911195 | 0.10 |
ENST00000259698.4
|
FAM65B
|
family with sequence similarity 65, member B |
chr6_-_52441713 | 0.10 |
ENST00000182527.3
|
TRAM2
|
translocation associated membrane protein 2 |
chr13_+_51796497 | 0.10 |
ENST00000322475.8
ENST00000280057.6 |
FAM124A
|
family with sequence similarity 124A |
chr10_+_51565108 | 0.10 |
ENST00000438493.1
ENST00000452682.1 |
NCOA4
|
nuclear receptor coactivator 4 |
chr19_+_4007644 | 0.10 |
ENST00000262971.2
|
PIAS4
|
protein inhibitor of activated STAT, 4 |
chr8_-_127570603 | 0.10 |
ENST00000304916.3
|
FAM84B
|
family with sequence similarity 84, member B |
chr12_-_51477333 | 0.10 |
ENST00000228515.1
ENST00000548206.1 ENST00000546935.1 ENST00000548981.1 |
CSRNP2
|
cysteine-serine-rich nuclear protein 2 |
chr17_+_17942594 | 0.10 |
ENST00000268719.4
|
GID4
|
GID complex subunit 4 |
chr2_+_16080659 | 0.10 |
ENST00000281043.3
|
MYCN
|
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog |
chr19_-_2721412 | 0.10 |
ENST00000323469.4
|
DIRAS1
|
DIRAS family, GTP-binding RAS-like 1 |
chr9_-_34126730 | 0.10 |
ENST00000361264.4
|
DCAF12
|
DDB1 and CUL4 associated factor 12 |
chr22_-_39640756 | 0.10 |
ENST00000331163.6
|
PDGFB
|
platelet-derived growth factor beta polypeptide |
chr5_+_32585605 | 0.10 |
ENST00000265073.4
ENST00000515355.1 ENST00000502897.1 ENST00000510442.1 |
SUB1
|
SUB1 homolog (S. cerevisiae) |
chr21_-_40685477 | 0.10 |
ENST00000342449.3
|
BRWD1
|
bromodomain and WD repeat domain containing 1 |
chr10_-_111683183 | 0.09 |
ENST00000403138.2
ENST00000369683.1 |
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
chr9_+_107509944 | 0.09 |
ENST00000374767.4
|
NIPSNAP3A
|
nipsnap homolog 3A (C. elegans) |
chr8_+_26435359 | 0.09 |
ENST00000311151.5
|
DPYSL2
|
dihydropyrimidinase-like 2 |
chr20_-_5591626 | 0.09 |
ENST00000379019.4
|
GPCPD1
|
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) |
chr4_+_52709229 | 0.09 |
ENST00000334635.5
ENST00000381441.3 ENST00000381437.4 |
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4 |
chr5_+_14664762 | 0.09 |
ENST00000284274.4
|
FAM105B
|
family with sequence similarity 105, member B |
chr2_+_54951679 | 0.09 |
ENST00000356458.6
|
EML6
|
echinoderm microtubule associated protein like 6 |
chr8_-_122653630 | 0.09 |
ENST00000303924.4
|
HAS2
|
hyaluronan synthase 2 |
chrX_+_49687216 | 0.09 |
ENST00000376088.3
|
CLCN5
|
chloride channel, voltage-sensitive 5 |
chr14_-_74253948 | 0.09 |
ENST00000394071.2
|
ELMSAN1
|
ELM2 and Myb/SANT-like domain containing 1 |
chr5_+_140345820 | 0.09 |
ENST00000289269.5
|
PCDHAC2
|
protocadherin alpha subfamily C, 2 |
chr7_+_135347215 | 0.09 |
ENST00000507606.1
|
C7orf73
|
chromosome 7 open reading frame 73 |
chr21_-_39288743 | 0.09 |
ENST00000609713.1
|
KCNJ6
|
potassium inwardly-rectifying channel, subfamily J, member 6 |
chr1_+_162351503 | 0.09 |
ENST00000458626.2
|
C1orf226
|
chromosome 1 open reading frame 226 |
chr12_+_3186521 | 0.09 |
ENST00000537971.1
ENST00000011898.5 |
TSPAN9
|
tetraspanin 9 |
chr2_+_179345173 | 0.09 |
ENST00000234453.5
|
PLEKHA3
|
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 |
chr4_+_17616253 | 0.09 |
ENST00000237380.7
|
MED28
|
mediator complex subunit 28 |
chr11_-_59383617 | 0.09 |
ENST00000263847.1
|
OSBP
|
oxysterol binding protein |
chr11_-_102962929 | 0.09 |
ENST00000260247.5
|
DCUN1D5
|
DCN1, defective in cullin neddylation 1, domain containing 5 |
chr5_-_78809950 | 0.09 |
ENST00000334082.6
|
HOMER1
|
homer homolog 1 (Drosophila) |
chr16_+_68298405 | 0.09 |
ENST00000219343.6
ENST00000566834.1 ENST00000566454.1 |
SLC7A6
|
solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 |
chr12_+_88536067 | 0.09 |
ENST00000549011.1
ENST00000266712.6 ENST00000551088.1 |
TMTC3
|
transmembrane and tetratricopeptide repeat containing 3 |
chr8_+_81397876 | 0.09 |
ENST00000430430.1
|
ZBTB10
|
zinc finger and BTB domain containing 10 |
chr6_+_106959718 | 0.09 |
ENST00000369066.3
|
AIM1
|
absent in melanoma 1 |
chr3_+_182971018 | 0.09 |
ENST00000326505.3
|
B3GNT5
|
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 |
chr2_+_88047606 | 0.09 |
ENST00000359481.4
|
PLGLB2
|
plasminogen-like B2 |
chr5_-_79551858 | 0.08 |
ENST00000507668.2
ENST00000512721.1 |
SERINC5
|
serine incorporator 5 |
chr7_+_116139424 | 0.08 |
ENST00000222693.4
|
CAV2
|
caveolin 2 |
chr5_+_122181184 | 0.08 |
ENST00000513881.1
|
SNX24
|
sorting nexin 24 |
chr17_-_1532106 | 0.08 |
ENST00000301335.5
ENST00000382147.4 |
SLC43A2
|
solute carrier family 43 (amino acid system L transporter), member 2 |
chr16_-_71758602 | 0.08 |
ENST00000568954.1
|
PHLPP2
|
PH domain and leucine rich repeat protein phosphatase 2 |
chr17_+_36508111 | 0.08 |
ENST00000331159.5
ENST00000577233.1 |
SOCS7
|
suppressor of cytokine signaling 7 |
chr2_-_190044480 | 0.08 |
ENST00000374866.3
|
COL5A2
|
collagen, type V, alpha 2 |
chr9_-_116172617 | 0.08 |
ENST00000374169.3
|
POLE3
|
polymerase (DNA directed), epsilon 3, accessory subunit |
chr7_+_139208413 | 0.08 |
ENST00000422142.2
|
CLEC2L
|
C-type lectin domain family 2, member L |
chr7_-_121036337 | 0.08 |
ENST00000426156.1
ENST00000359943.3 ENST00000412653.1 |
FAM3C
|
family with sequence similarity 3, member C |
chr12_+_50898881 | 0.08 |
ENST00000301180.5
|
DIP2B
|
DIP2 disco-interacting protein 2 homolog B (Drosophila) |
chr5_+_153418466 | 0.08 |
ENST00000522782.1
ENST00000439768.2 ENST00000436816.1 ENST00000322602.5 ENST00000522177.1 ENST00000520899.1 |
MFAP3
|
microfibrillar-associated protein 3 |
chr3_+_140950612 | 0.08 |
ENST00000286353.4
ENST00000502783.1 ENST00000393010.2 ENST00000514680.1 |
ACPL2
|
acid phosphatase-like 2 |
chr10_-_11653753 | 0.08 |
ENST00000609104.1
|
USP6NL
|
USP6 N-terminal like |
chr2_+_61108650 | 0.08 |
ENST00000295025.8
|
REL
|
v-rel avian reticuloendotheliosis viral oncogene homolog |
chr20_-_45035223 | 0.08 |
ENST00000450812.1
ENST00000290246.6 ENST00000439931.2 ENST00000396391.1 |
ELMO2
|
engulfment and cell motility 2 |
chr10_-_113943447 | 0.08 |
ENST00000369425.1
ENST00000348367.4 ENST00000423155.1 |
GPAM
|
glycerol-3-phosphate acyltransferase, mitochondrial |
chr5_-_178772424 | 0.08 |
ENST00000251582.7
ENST00000274609.5 |
ADAMTS2
|
ADAM metallopeptidase with thrombospondin type 1 motif, 2 |
chr12_+_53774423 | 0.08 |
ENST00000426431.2
|
SP1
|
Sp1 transcription factor |
chr17_-_37557846 | 0.08 |
ENST00000394294.3
ENST00000583610.1 ENST00000264658.6 |
FBXL20
|
F-box and leucine-rich repeat protein 20 |
chr12_+_13349650 | 0.08 |
ENST00000256951.5
ENST00000431267.2 ENST00000542474.1 ENST00000544053.1 |
EMP1
|
epithelial membrane protein 1 |
chr22_-_30642728 | 0.08 |
ENST00000403987.3
|
LIF
|
leukemia inhibitory factor |
chr9_-_112083229 | 0.08 |
ENST00000374566.3
ENST00000374557.4 |
EPB41L4B
|
erythrocyte membrane protein band 4.1 like 4B |
chr1_-_38019878 | 0.08 |
ENST00000296215.6
|
SNIP1
|
Smad nuclear interacting protein 1 |
chr17_+_38278530 | 0.07 |
ENST00000398532.4
|
MSL1
|
male-specific lethal 1 homolog (Drosophila) |
chr5_+_112043186 | 0.07 |
ENST00000509732.1
ENST00000457016.1 ENST00000507379.1 |
APC
|
adenomatous polyposis coli |
chr17_+_38333263 | 0.07 |
ENST00000456989.2
ENST00000543876.1 ENST00000544503.1 ENST00000264644.6 ENST00000538884.1 |
RAPGEFL1
|
Rap guanine nucleotide exchange factor (GEF)-like 1 |
chrX_+_9754461 | 0.07 |
ENST00000380913.3
|
SHROOM2
|
shroom family member 2 |
chr10_+_17794251 | 0.07 |
ENST00000377495.1
ENST00000338221.5 |
TMEM236
|
transmembrane protein 236 |
chr1_-_103574024 | 0.07 |
ENST00000512756.1
ENST00000370096.3 ENST00000358392.2 ENST00000353414.4 |
COL11A1
|
collagen, type XI, alpha 1 |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.7 | GO:0018277 | protein deamination(GO:0018277) |
0.1 | 0.3 | GO:0071879 | positive regulation of adrenergic receptor signaling pathway(GO:0071879) |
0.1 | 0.3 | GO:0061580 | colon epithelial cell migration(GO:0061580) |
0.1 | 0.2 | GO:1903348 | positive regulation of bicellular tight junction assembly(GO:1903348) |
0.1 | 0.2 | GO:0072573 | regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349) |
0.1 | 0.2 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
0.1 | 0.2 | GO:0015728 | mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780) |
0.1 | 0.2 | GO:1903778 | protein localization to vacuolar membrane(GO:1903778) |
0.0 | 0.2 | GO:0036343 | psychomotor behavior(GO:0036343) |
0.0 | 0.1 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
0.0 | 0.1 | GO:0032290 | peripheral nervous system myelin formation(GO:0032290) |
0.0 | 0.1 | GO:0021761 | limbic system development(GO:0021761) hippocampus development(GO:0021766) |
0.0 | 0.1 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
0.0 | 0.1 | GO:2000588 | positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588) |
0.0 | 0.1 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
0.0 | 0.1 | GO:1990927 | vesicle-mediated cholesterol transport(GO:0090119) short-term synaptic potentiation(GO:1990926) calcium ion regulated lysosome exocytosis(GO:1990927) |
0.0 | 0.3 | GO:0000066 | mitochondrial ornithine transport(GO:0000066) |
0.0 | 0.2 | GO:0035494 | SNARE complex disassembly(GO:0035494) |
0.0 | 0.2 | GO:0032455 | nerve growth factor processing(GO:0032455) |
0.0 | 0.3 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
0.0 | 0.1 | GO:0035526 | retrograde transport, plasma membrane to Golgi(GO:0035526) |
0.0 | 0.2 | GO:0071651 | positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651) |
0.0 | 0.1 | GO:0008057 | eye pigment granule organization(GO:0008057) |
0.0 | 0.1 | GO:0060086 | circadian temperature homeostasis(GO:0060086) |
0.0 | 0.1 | GO:1990936 | metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936) |
0.0 | 0.2 | GO:0007296 | vitellogenesis(GO:0007296) |
0.0 | 0.1 | GO:2000646 | positive regulation of receptor catabolic process(GO:2000646) |
0.0 | 0.1 | GO:0033031 | positive regulation of neutrophil apoptotic process(GO:0033031) |
0.0 | 0.1 | GO:0045226 | extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) |
0.0 | 0.3 | GO:0048251 | elastic fiber assembly(GO:0048251) |
0.0 | 0.1 | GO:1990709 | presynaptic active zone organization(GO:1990709) |
0.0 | 0.1 | GO:2000969 | positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969) |
0.0 | 0.1 | GO:0051835 | positive regulation of synapse structural plasticity(GO:0051835) |
0.0 | 0.1 | GO:0035624 | receptor transactivation(GO:0035624) |
0.0 | 0.2 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
0.0 | 0.1 | GO:0046619 | optic placode formation involved in camera-type eye formation(GO:0046619) |
0.0 | 0.4 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
0.0 | 0.1 | GO:0035544 | negative regulation of SNARE complex assembly(GO:0035544) |
0.0 | 0.1 | GO:1900239 | phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239) |
0.0 | 0.2 | GO:0050653 | chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653) |
0.0 | 0.1 | GO:0061300 | cerebellum vasculature development(GO:0061300) |
0.0 | 0.2 | GO:0010993 | regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) |
0.0 | 0.1 | GO:0090625 | mRNA cleavage involved in gene silencing by siRNA(GO:0090625) |
0.0 | 0.1 | GO:0010710 | regulation of collagen catabolic process(GO:0010710) |
0.0 | 0.1 | GO:0019065 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
0.0 | 0.1 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
0.0 | 0.1 | GO:0035582 | sequestering of BMP in extracellular matrix(GO:0035582) |
0.0 | 0.1 | GO:0038172 | interleukin-33-mediated signaling pathway(GO:0038172) |
0.0 | 0.1 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
0.0 | 0.2 | GO:0002480 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) |
0.0 | 0.2 | GO:0030422 | production of siRNA involved in RNA interference(GO:0030422) |
0.0 | 0.1 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
0.0 | 0.1 | GO:0002316 | follicular B cell differentiation(GO:0002316) |
0.0 | 0.2 | GO:0051901 | positive regulation of mitochondrial depolarization(GO:0051901) |
0.0 | 0.1 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
0.0 | 0.0 | GO:0071109 | superior temporal gyrus development(GO:0071109) |
0.0 | 0.0 | GO:1902309 | regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
0.0 | 0.1 | GO:1904219 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
0.0 | 0.2 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
0.0 | 0.1 | GO:0031291 | Ran protein signal transduction(GO:0031291) |
0.0 | 0.1 | GO:0051549 | positive regulation of keratinocyte migration(GO:0051549) |
0.0 | 0.1 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
0.0 | 0.2 | GO:0070327 | thyroid hormone transport(GO:0070327) |
0.0 | 0.0 | GO:0045081 | negative regulation of interleukin-10 biosynthetic process(GO:0045081) |
0.0 | 0.2 | GO:0045636 | positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913) |
0.0 | 0.2 | GO:0045793 | positive regulation of cell size(GO:0045793) |
0.0 | 0.1 | GO:2001137 | positive regulation of endocytic recycling(GO:2001137) |
0.0 | 0.3 | GO:0034656 | nucleobase-containing small molecule catabolic process(GO:0034656) |
0.0 | 0.1 | GO:0015820 | leucine transport(GO:0015820) |
0.0 | 0.1 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
0.0 | 0.0 | GO:0046103 | adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103) |
0.0 | 0.1 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
0.0 | 0.3 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
0.0 | 0.3 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
0.0 | 0.0 | GO:0019085 | early viral transcription(GO:0019085) |
0.0 | 0.1 | GO:0035989 | tendon development(GO:0035989) |
0.0 | 0.1 | GO:0072501 | cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502) |
0.0 | 0.2 | GO:0015074 | DNA integration(GO:0015074) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.2 | GO:0030934 | anchoring collagen complex(GO:0030934) |
0.0 | 0.1 | GO:0034677 | integrin alpha7-beta1 complex(GO:0034677) |
0.0 | 0.2 | GO:0031905 | early endosome lumen(GO:0031905) |
0.0 | 0.1 | GO:0043260 | laminin-1 complex(GO:0005606) laminin-11 complex(GO:0043260) |
0.0 | 0.3 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
0.0 | 0.1 | GO:0097635 | extrinsic component of autophagosome membrane(GO:0097635) |
0.0 | 0.3 | GO:0070578 | RISC-loading complex(GO:0070578) |
0.0 | 0.2 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.0 | 0.0 | GO:0032002 | interleukin-28 receptor complex(GO:0032002) |
0.0 | 0.3 | GO:0005916 | fascia adherens(GO:0005916) |
0.0 | 0.3 | GO:0032433 | filopodium tip(GO:0032433) |
0.0 | 0.1 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
0.0 | 0.1 | GO:0001520 | outer dense fiber(GO:0001520) |
0.0 | 0.0 | GO:0005588 | collagen type V trimer(GO:0005588) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.0 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
0.1 | 0.3 | GO:0003943 | N-acetylgalactosamine-4-sulfatase activity(GO:0003943) |
0.1 | 0.2 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
0.1 | 0.2 | GO:0015130 | mevalonate transmembrane transporter activity(GO:0015130) |
0.0 | 0.1 | GO:0005169 | neurotrophin TRKB receptor binding(GO:0005169) |
0.0 | 0.1 | GO:0030350 | iron-responsive element binding(GO:0030350) |
0.0 | 0.3 | GO:0000064 | L-ornithine transmembrane transporter activity(GO:0000064) |
0.0 | 0.1 | GO:0047389 | glycerophosphocholine phosphodiesterase activity(GO:0047389) |
0.0 | 0.1 | GO:0032427 | GBD domain binding(GO:0032427) |
0.0 | 0.1 | GO:0004366 | glycerol-3-phosphate O-acyltransferase activity(GO:0004366) |
0.0 | 0.1 | GO:0005146 | leukemia inhibitory factor receptor binding(GO:0005146) |
0.0 | 0.1 | GO:0004947 | bradykinin receptor activity(GO:0004947) |
0.0 | 0.1 | GO:0004874 | aryl hydrocarbon receptor activity(GO:0004874) |
0.0 | 0.1 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
0.0 | 0.1 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
0.0 | 0.2 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
0.0 | 0.1 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
0.0 | 0.1 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
0.0 | 0.1 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
0.0 | 0.1 | GO:0008457 | beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256) |
0.0 | 0.2 | GO:0070883 | pre-miRNA binding(GO:0070883) |
0.0 | 0.1 | GO:0046404 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
0.0 | 0.1 | GO:0001025 | RNA polymerase III transcription factor binding(GO:0001025) |
0.0 | 0.1 | GO:0002114 | interleukin-33 receptor activity(GO:0002114) |
0.0 | 0.1 | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) |
0.0 | 0.2 | GO:0047238 | glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238) |
0.0 | 0.2 | GO:0048019 | receptor antagonist activity(GO:0048019) |
0.0 | 0.1 | GO:0034046 | poly(G) binding(GO:0034046) |
0.0 | 0.2 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
0.0 | 0.0 | GO:0051373 | FATZ binding(GO:0051373) |
0.0 | 0.0 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
0.0 | 0.0 | GO:0031626 | beta-endorphin binding(GO:0031626) |
0.0 | 0.2 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
0.0 | 0.1 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
0.0 | 0.0 | GO:0043739 | G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739) |
0.0 | 0.1 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
0.0 | 0.2 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.0 | 0.2 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
0.0 | 0.1 | GO:0061665 | SUMO ligase activity(GO:0061665) |
0.0 | 0.0 | GO:0050309 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
0.0 | 0.3 | GO:0045294 | alpha-catenin binding(GO:0045294) |
0.0 | 0.2 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
0.0 | 0.3 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
0.0 | 0.1 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) |
0.0 | 0.2 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
0.0 | 0.1 | GO:0038049 | transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.1 | PID ER NONGENOMIC PATHWAY | Plasma membrane estrogen receptor signaling |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.2 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
0.0 | 0.3 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
0.0 | 0.1 | REACTOME SIGNALING BY EGFR IN CANCER | Genes involved in Signaling by EGFR in Cancer |
0.0 | 0.2 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
0.0 | 0.1 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
0.0 | 0.1 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |