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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for AIRE

Z-value: 1.15

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Transcription factors associated with AIRE

Gene Symbol Gene ID Gene Info
AIRE
ENSG00000160224.12 autoimmune regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
AIREhg19_v2_chr21_+_45705752_457057670.316.9e-01Click!

Activity profile of AIRE motif

Sorted Z-values of AIRE motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_75874580 2.38 ENST00000456650.3
GLIPR1
GLI pathogenesis-related 1
chr12_+_75874984 2.36 ENST00000550491.1
GLIPR1
GLI pathogenesis-related 1
chr1_+_79115503 1.68 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr12_+_75874460 1.29 ENST00000266659.3
GLIPR1
GLI pathogenesis-related 1
chr11_-_327537 1.12 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr22_+_36649170 1.10 ENST00000438034.1
ENST00000427990.1
ENST00000347595.7
ENST00000397279.4
ENST00000433768.1
ENST00000440669.2
APOL1
apolipoprotein L, 1
chr5_-_38845812 0.92 ENST00000513480.1
ENST00000512519.1
CTD-2127H9.1
CTD-2127H9.1
chr19_-_23869999 0.86 ENST00000601935.1
ENST00000359788.4
ENST00000600313.1
ENST00000596211.1
ENST00000599168.1
ZNF675
zinc finger protein 675
chr22_+_36649056 0.86 ENST00000397278.3
ENST00000422706.1
ENST00000426053.1
ENST00000319136.4
APOL1
apolipoprotein L, 1
chr1_-_154600421 0.77 ENST00000368471.3
ENST00000292205.5
ADAR
adenosine deaminase, RNA-specific
chr12_+_52643077 0.59 ENST00000553310.2
ENST00000544024.1
KRT86
keratin 86
chrM_+_8366 0.55 ENST00000361851.1
MT-ATP8
mitochondrially encoded ATP synthase 8
chrM_+_12331 0.51 ENST00000361567.2
MT-ND5
mitochondrially encoded NADH dehydrogenase 5
chr11_+_107650219 0.48 ENST00000398067.1
AP001024.1
Uncharacterized protein
chr10_+_90660832 0.47 ENST00000371924.1
STAMBPL1
STAM binding protein-like 1
chr1_-_52456352 0.43 ENST00000371655.3
RAB3B
RAB3B, member RAS oncogene family
chr10_-_75682535 0.41 ENST00000409178.1
C10orf55
chromosome 10 open reading frame 55
chrM_+_7586 0.38 ENST00000361739.1
MT-CO2
mitochondrially encoded cytochrome c oxidase II
chr1_+_40840320 0.36 ENST00000372708.1
SMAP2
small ArfGAP2
chr19_-_21950362 0.36 ENST00000358296.6
ZNF100
zinc finger protein 100
chr6_-_32806506 0.36 ENST00000374897.2
ENST00000452392.2
TAP2
TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Uncharacterized protein
chrM_-_14670 0.35 ENST00000361681.2
MT-ND6
mitochondrially encoded NADH dehydrogenase 6
chr12_-_113772835 0.35 ENST00000552014.1
ENST00000548186.1
ENST00000202831.3
ENST00000549181.1
SLC8B1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr9_-_25678856 0.35 ENST00000358022.3
TUSC1
tumor suppressor candidate 1
chr6_-_31514516 0.34 ENST00000303892.5
ENST00000483251.1
ATP6V1G2
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr17_+_77030267 0.34 ENST00000581774.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr6_+_127898312 0.34 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr7_+_142374104 0.33 ENST00000604952.1
MTRNR2L6
MT-RNR2-like 6
chr1_-_161208013 0.33 ENST00000515452.1
ENST00000367983.4
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr20_-_43150601 0.33 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
SERINC3
serine incorporator 3
chrX_-_49041242 0.32 ENST00000453382.1
ENST00000540849.1
ENST00000536904.1
ENST00000432913.1
PRICKLE3
prickle homolog 3 (Drosophila)
chr2_-_127977654 0.30 ENST00000409327.1
CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr3_+_140981456 0.30 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chrM_+_4431 0.30 ENST00000361453.3
MT-ND2
mitochondrially encoded NADH dehydrogenase 2
chr19_-_47249679 0.28 ENST00000263280.6
STRN4
striatin, calmodulin binding protein 4
chr10_-_4720333 0.27 ENST00000430998.2
LINC00704
long intergenic non-protein coding RNA 704
chr4_-_120243545 0.26 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr15_-_83209210 0.26 ENST00000561157.1
ENST00000330244.6
RPS17L
ribosomal protein S17-like
chr19_-_23869970 0.26 ENST00000601010.1
ZNF675
zinc finger protein 675
chrM_+_14741 0.25 ENST00000361789.2
MT-CYB
mitochondrially encoded cytochrome b
chr6_-_127663543 0.25 ENST00000531582.1
ECHDC1
enoyl CoA hydratase domain containing 1
chr19_-_48753028 0.24 ENST00000522431.1
CARD8
caspase recruitment domain family, member 8
chr4_-_120222076 0.23 ENST00000504110.1
C4orf3
chromosome 4 open reading frame 3
chr5_-_77844974 0.23 ENST00000515007.2
LHFPL2
lipoma HMGIC fusion partner-like 2
chr15_+_45938079 0.23 ENST00000561493.1
SQRDL
sulfide quinone reductase-like (yeast)
chr1_-_161207986 0.22 ENST00000506209.1
ENST00000367980.2
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr5_+_122181279 0.22 ENST00000395451.4
ENST00000506996.1
SNX24
sorting nexin 24
chrM_+_5824 0.22 ENST00000361624.2
MT-CO1
mitochondrially encoded cytochrome c oxidase I
chr4_+_69917078 0.22 ENST00000502942.1
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr2_-_198540751 0.22 ENST00000429081.1
RFTN2
raftlin family member 2
chr12_+_7282795 0.22 ENST00000266546.6
CLSTN3
calsyntenin 3
chr2_-_225811747 0.22 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr13_-_30160925 0.21 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr16_+_3254247 0.21 ENST00000304646.2
OR1F1
olfactory receptor, family 1, subfamily F, member 1
chr4_+_71588372 0.21 ENST00000536664.1
RUFY3
RUN and FYVE domain containing 3
chr14_-_46185155 0.21 ENST00000555442.1
RP11-369C8.1
RP11-369C8.1
chr2_-_136633940 0.20 ENST00000264156.2
MCM6
minichromosome maintenance complex component 6
chr9_+_71986182 0.19 ENST00000303068.7
FAM189A2
family with sequence similarity 189, member A2
chr6_+_168434678 0.19 ENST00000496008.1
KIF25
kinesin family member 25
chr12_+_20848486 0.19 ENST00000545102.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr11_-_119249805 0.19 ENST00000527843.1
USP2
ubiquitin specific peptidase 2
chr19_-_59084922 0.18 ENST00000215057.2
ENST00000599369.1
MZF1
myeloid zinc finger 1
chr5_+_122181184 0.18 ENST00000513881.1
SNX24
sorting nexin 24
chr22_-_32767017 0.18 ENST00000400234.1
RFPL3S
RFPL3 antisense
chr13_-_46756351 0.18 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chrX_-_139866723 0.18 ENST00000370532.2
CDR1
cerebellar degeneration-related protein 1, 34kDa
chr12_-_6579808 0.17 ENST00000535180.1
ENST00000400911.3
VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr17_+_41857793 0.17 ENST00000449302.3
C17orf105
chromosome 17 open reading frame 105
chr16_-_29499154 0.16 ENST00000354563.5
RP11-231C14.4
Uncharacterized protein
chr19_-_52552051 0.16 ENST00000221315.5
ZNF432
zinc finger protein 432
chr12_-_25101920 0.16 ENST00000539780.1
ENST00000546285.1
ENST00000342945.5
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr3_-_33686925 0.15 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chr9_-_4666421 0.15 ENST00000381895.5
SPATA6L
spermatogenesis associated 6-like
chr16_+_14802801 0.15 ENST00000526520.1
ENST00000531598.2
NPIPA3
nuclear pore complex interacting protein family, member A3
chr16_-_31147020 0.15 ENST00000568261.1
ENST00000567797.1
ENST00000317508.6
PRSS8
protease, serine, 8
chr10_+_115511434 0.15 ENST00000369312.4
PLEKHS1
pleckstrin homology domain containing, family S member 1
chr11_-_85376121 0.15 ENST00000527447.1
CREBZF
CREB/ATF bZIP transcription factor
chr6_+_36839616 0.15 ENST00000359359.2
ENST00000510325.2
C6orf89
chromosome 6 open reading frame 89
chr4_-_4544061 0.14 ENST00000507908.1
STX18
syntaxin 18
chr8_-_145652336 0.14 ENST00000529182.1
ENST00000526054.1
VPS28
vacuolar protein sorting 28 homolog (S. cerevisiae)
chr2_+_219840955 0.14 ENST00000598002.1
ENST00000432733.1
LINC00608
long intergenic non-protein coding RNA 608
chr4_-_123843597 0.14 ENST00000510735.1
ENST00000304430.5
NUDT6
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr9_-_114362093 0.14 ENST00000538962.1
ENST00000407693.2
ENST00000238248.3
PTGR1
prostaglandin reductase 1
chr9_-_114361665 0.14 ENST00000309195.5
PTGR1
prostaglandin reductase 1
chr16_-_89119355 0.13 ENST00000537498.1
CTD-2555A7.2
CTD-2555A7.2
chr9_-_21482312 0.13 ENST00000448696.3
IFNE
interferon, epsilon
chrX_-_153192211 0.13 ENST00000461052.1
ENST00000422091.1
ARHGAP4
Rho GTPase activating protein 4
chr2_-_166060571 0.12 ENST00000360093.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr8_+_54764346 0.12 ENST00000297313.3
ENST00000344277.6
RGS20
regulator of G-protein signaling 20
chr2_+_204732487 0.12 ENST00000302823.3
CTLA4
cytotoxic T-lymphocyte-associated protein 4
chr6_+_42584847 0.12 ENST00000372883.3
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr1_+_198189921 0.12 ENST00000391974.3
NEK7
NIMA-related kinase 7
chr1_+_100810575 0.12 ENST00000542213.1
CDC14A
cell division cycle 14A
chr1_+_241815577 0.12 ENST00000366552.2
ENST00000437684.2
WDR64
WD repeat domain 64
chr6_-_33266687 0.12 ENST00000444031.2
RGL2
ral guanine nucleotide dissociation stimulator-like 2
chr20_-_33735070 0.11 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr8_-_141728444 0.11 ENST00000521562.1
PTK2
protein tyrosine kinase 2
chrX_-_153191674 0.11 ENST00000350060.5
ENST00000370016.1
ARHGAP4
Rho GTPase activating protein 4
chr7_+_76101379 0.10 ENST00000429179.1
DTX2
deltex homolog 2 (Drosophila)
chr1_-_52344471 0.10 ENST00000352171.7
ENST00000354831.7
NRD1
nardilysin (N-arginine dibasic convertase)
chrX_-_153191708 0.10 ENST00000393721.1
ENST00000370028.3
ARHGAP4
Rho GTPase activating protein 4
chr11_+_64794875 0.10 ENST00000377244.3
ENST00000534637.1
ENST00000524831.1
SNX15
sorting nexin 15
chr2_+_201981663 0.10 ENST00000433445.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr12_-_6580094 0.09 ENST00000361716.3
VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr3_+_193965426 0.09 ENST00000455821.1
RP11-513G11.3
RP11-513G11.3
chr6_-_106773610 0.09 ENST00000369076.3
ENST00000369070.1
ATG5
autophagy related 5
chr4_-_16085657 0.09 ENST00000543373.1
PROM1
prominin 1
chr16_+_11439286 0.09 ENST00000312499.5
ENST00000576027.1
RMI2
RecQ mediated genome instability 2
chr17_-_191188 0.09 ENST00000575634.1
RPH3AL
rabphilin 3A-like (without C2 domains)
chr9_-_79267432 0.08 ENST00000424866.1
PRUNE2
prune homolog 2 (Drosophila)
chr13_+_111893533 0.08 ENST00000478679.1
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr19_-_52551814 0.08 ENST00000594154.1
ENST00000598745.1
ENST00000597273.1
ZNF432
zinc finger protein 432
chr6_+_22221010 0.08 ENST00000567753.1
RP11-524C21.2
RP11-524C21.2
chr7_+_20686946 0.08 ENST00000443026.2
ENST00000406935.1
ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr1_+_36038971 0.08 ENST00000373235.3
TFAP2E
transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
chr10_-_46030841 0.08 ENST00000453424.2
MARCH8
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
chr11_+_64794991 0.07 ENST00000352068.5
ENST00000525648.1
SNX15
sorting nexin 15
chr1_+_207669573 0.06 ENST00000400960.2
ENST00000534202.1
CR1
complement component (3b/4b) receptor 1 (Knops blood group)
chr11_+_6947647 0.06 ENST00000278319.5
ZNF215
zinc finger protein 215
chr4_-_66536057 0.06 ENST00000273854.3
EPHA5
EPH receptor A5
chr8_+_24241789 0.06 ENST00000256412.4
ENST00000538205.1
ADAMDEC1
ADAM-like, decysin 1
chr16_+_72088376 0.06 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP
HPR
haptoglobin
haptoglobin-related protein
chr15_+_27112948 0.06 ENST00000555060.1
GABRA5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr1_-_52344416 0.06 ENST00000544028.1
NRD1
nardilysin (N-arginine dibasic convertase)
chr18_+_39739223 0.06 ENST00000601948.1
LINC00907
long intergenic non-protein coding RNA 907
chr4_+_1385340 0.06 ENST00000324803.4
CRIPAK
cysteine-rich PAK1 inhibitor
chrX_-_101694853 0.05 ENST00000372749.1
NXF2B
nuclear RNA export factor 2B
chr19_+_45417921 0.05 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
APOC1
apolipoprotein C-I
chr22_+_42017987 0.05 ENST00000405506.1
XRCC6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr7_-_36764004 0.05 ENST00000431169.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr1_-_152297679 0.05 ENST00000368799.1
FLG
filaggrin
chr6_-_31514333 0.05 ENST00000376151.4
ATP6V1G2
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr6_+_167525277 0.04 ENST00000400926.2
CCR6
chemokine (C-C motif) receptor 6
chr19_-_48753104 0.04 ENST00000447740.2
CARD8
caspase recruitment domain family, member 8
chr3_-_123710199 0.04 ENST00000184183.4
ROPN1
rhophilin associated tail protein 1
chr4_+_156775910 0.04 ENST00000506072.1
ENST00000507590.1
TDO2
tryptophan 2,3-dioxygenase
chr10_-_106240032 0.04 ENST00000447860.1
RP11-127O4.3
RP11-127O4.3
chr4_+_71587669 0.04 ENST00000381006.3
ENST00000226328.4
RUFY3
RUN and FYVE domain containing 3
chr9_-_104198042 0.04 ENST00000374855.4
ALDOB
aldolase B, fructose-bisphosphate
chr3_-_139199565 0.04 ENST00000511956.1
RBP2
retinol binding protein 2, cellular
chr14_-_106668095 0.03 ENST00000390606.2
IGHV3-20
immunoglobulin heavy variable 3-20
chr19_-_48752812 0.03 ENST00000359009.4
CARD8
caspase recruitment domain family, member 8
chr12_+_12202774 0.03 ENST00000589718.1
BCL2L14
BCL2-like 14 (apoptosis facilitator)
chr9_-_70178815 0.03 ENST00000377420.1
FOXD4L5
forkhead box D4-like 5
chr19_+_45418067 0.03 ENST00000589078.1
ENST00000586638.1
APOC1
apolipoprotein C-I
chr18_-_37380230 0.03 ENST00000591629.1
LINC00669
long intergenic non-protein coding RNA 669
chr21_+_30673091 0.02 ENST00000447177.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr2_-_166810261 0.02 ENST00000243344.7
TTC21B
tetratricopeptide repeat domain 21B
chr21_+_39644305 0.02 ENST00000398930.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr21_+_39644172 0.02 ENST00000398932.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr19_-_16606988 0.02 ENST00000269881.3
CALR3
calreticulin 3
chr15_+_52043813 0.02 ENST00000435126.2
TMOD2
tropomodulin 2 (neuronal)
chr16_+_50914085 0.02 ENST00000576842.1
CTD-2034I21.2
CTD-2034I21.2
chr15_-_52043722 0.02 ENST00000454181.2
LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2
chr9_+_42717234 0.02 ENST00000377590.1
FOXD4L2
forkhead box D4-like 2
chr12_-_6579833 0.02 ENST00000396308.3
VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr19_+_56751773 0.02 ENST00000600684.1
ZSCAN5D
zinc finger and SCAN domain containing 5D
chr14_-_24912047 0.02 ENST00000553930.1
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr17_+_7210294 0.02 ENST00000336452.7
EIF5A
eukaryotic translation initiation factor 5A
chr9_-_70429731 0.01 ENST00000377413.1
FOXD4L4
forkhead box D4-like 4
chr1_-_91813006 0.01 ENST00000430465.1
HFM1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr4_+_78829479 0.01 ENST00000504901.1
MRPL1
mitochondrial ribosomal protein L1
chr20_+_21284416 0.00 ENST00000539513.1
XRN2
5'-3' exoribonuclease 2
chr10_+_115511213 0.00 ENST00000361048.1
PLEKHS1
pleckstrin homology domain containing, family S member 1
chr14_-_24911971 0.00 ENST00000555365.1
ENST00000399395.3
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr12_-_15038779 0.00 ENST00000228938.5
ENST00000539261.1
MGP
matrix Gla protein
chr16_+_57126428 0.00 ENST00000290776.8
CPNE2
copine II
chr15_-_81202118 0.00 ENST00000560560.1
RP11-351M8.1
Uncharacterized protein
chr2_+_62423242 0.00 ENST00000301998.4
B3GNT2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of AIRE

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 1.1 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.4 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.1 0.4 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.2 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.1 GO:2000397 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 2.0 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 0.3 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.2 GO:0097327 response to antineoplastic agent(GO:0097327)
0.0 0.3 GO:0009597 detection of virus(GO:0009597)
0.0 1.1 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.1 GO:1902573 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.0 0.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.2 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.1 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.3 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.1 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.1 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 0.6 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.1 GO:0048749 compound eye development(GO:0048749)
0.0 0.3 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.0 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.2 GO:0032596 protein transport into membrane raft(GO:0032596)
0.0 1.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.0 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.0 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.1 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 2.0 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 6.3 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 0.4 GO:0042825 TAP complex(GO:0042825)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.3 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.3 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.0 GO:0036457 keratohyalin granule(GO:0036457)
0.0 0.4 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 1.0 GO:0070469 respiratory chain(GO:0070469)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.3 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.6 GO:0004882 androgen receptor activity(GO:0004882)
0.1 0.2 GO:0032440 2-alkenal reductase [NAD(P)] activity(GO:0032440)
0.1 0.4 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 0.2 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.1 0.3 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.2 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0001855 complement component C4b binding(GO:0001855)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 1.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 2.0 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.0 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 6.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins