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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for BACH1_NFE2_NFE2L2

Z-value: 1.79

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Transcription factors associated with BACH1_NFE2_NFE2L2

Gene Symbol Gene ID Gene Info
BACH1
ENSG00000156273.11 BTB domain and CNC homolog 1
NFE2
ENSG00000123405.9 nuclear factor, erythroid 2
NFE2L2
ENSG00000116044.11 nuclear factor, erythroid 2 like 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFE2hg19_v2_chr12_-_54694758_54694805-0.703.0e-01Click!
NFE2L2hg19_v2_chr2_-_178129551_178129572-0.653.5e-01Click!
BACH1hg19_v2_chr21_+_30673091_306731350.623.8e-01Click!

Activity profile of BACH1_NFE2_NFE2L2 motif

Sorted Z-values of BACH1_NFE2_NFE2L2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_116840728 2.32 ENST00000265132.3
AMBP
alpha-1-microglobulin/bikunin precursor
chr4_-_987164 1.24 ENST00000398520.2
SLC26A1
solute carrier family 26 (anion exchanger), member 1
chr20_+_48909240 1.15 ENST00000371639.3
RP11-290F20.1
RP11-290F20.1
chr11_+_67351213 1.07 ENST00000398603.1
GSTP1
glutathione S-transferase pi 1
chr11_+_67351019 1.06 ENST00000398606.3
GSTP1
glutathione S-transferase pi 1
chr2_-_220117867 1.03 ENST00000456818.1
ENST00000447205.1
TUBA4A
tubulin, alpha 4a
chr11_-_2924720 1.03 ENST00000455942.2
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr22_+_45072925 1.01 ENST00000006251.7
PRR5
proline rich 5 (renal)
chr19_+_49467232 0.98 ENST00000599784.1
ENST00000594305.1
CTD-2639E6.9
CTD-2639E6.9
chr18_-_55253989 0.97 ENST00000262093.5
FECH
ferrochelatase
chr11_-_111794446 0.95 ENST00000527950.1
CRYAB
crystallin, alpha B
chrX_+_153769446 0.92 ENST00000422680.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chrX_-_15511438 0.85 ENST00000380420.5
PIR
pirin (iron-binding nuclear protein)
chr16_-_69760409 0.82 ENST00000561500.1
ENST00000439109.2
ENST00000564043.1
ENST00000379046.2
ENST00000379047.3
NQO1
NAD(P)H dehydrogenase, quinone 1
chr7_+_134212312 0.81 ENST00000359579.4
AKR1B10
aldo-keto reductase family 1, member B10 (aldose reductase)
chr18_-_55253900 0.81 ENST00000585747.1
ENST00000592699.1
FECH
ferrochelatase
chr10_+_115312766 0.80 ENST00000351270.3
HABP2
hyaluronan binding protein 2
chr22_+_45072958 0.77 ENST00000403581.1
PRR5
proline rich 5 (renal)
chr16_-_1429627 0.77 ENST00000248104.7
UNKL
unkempt family zinc finger-like
chr16_+_83986827 0.76 ENST00000393306.1
ENST00000565123.1
OSGIN1
oxidative stress induced growth inhibitor 1
chr1_-_225616515 0.76 ENST00000338179.2
ENST00000425080.1
LBR
lamin B receptor
chr9_+_92219919 0.75 ENST00000252506.6
ENST00000375769.1
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr12_+_56075330 0.73 ENST00000394252.3
METTL7B
methyltransferase like 7B
chr1_+_17634689 0.73 ENST00000375453.1
ENST00000375448.4
PADI4
peptidyl arginine deiminase, type IV
chr6_-_84140757 0.72 ENST00000541327.1
ENST00000369705.3
ENST00000543031.1
ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr17_+_76311791 0.71 ENST00000586321.1
AC061992.2
AC061992.2
chr9_-_113018746 0.70 ENST00000374515.5
TXN
thioredoxin
chr2_-_220083076 0.70 ENST00000295750.4
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr16_+_47496023 0.67 ENST00000567200.1
PHKB
phosphorylase kinase, beta
chr20_+_44637526 0.65 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr12_-_49523896 0.65 ENST00000549870.1
TUBA1B
tubulin, alpha 1b
chr19_-_10613862 0.64 ENST00000592055.1
KEAP1
kelch-like ECH-associated protein 1
chr8_-_95220775 0.63 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr17_-_79881408 0.63 ENST00000392366.3
MAFG
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr14_-_65409502 0.62 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr20_-_48782639 0.62 ENST00000435301.2
RP11-112L6.3
RP11-112L6.3
chr10_-_93392811 0.61 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr5_+_35852797 0.60 ENST00000508941.1
IL7R
interleukin 7 receptor
chr18_-_68004529 0.60 ENST00000578633.1
RP11-484N16.1
RP11-484N16.1
chr18_-_55253871 0.57 ENST00000382873.3
FECH
ferrochelatase
chr2_+_54342574 0.57 ENST00000303536.4
ENST00000394666.3
ACYP2
acylphosphatase 2, muscle type
chrX_+_153770421 0.57 ENST00000369609.5
ENST00000369607.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr15_-_76304731 0.57 ENST00000394907.3
NRG4
neuregulin 4
chr2_-_11605966 0.56 ENST00000307236.4
ENST00000542100.1
ENST00000546212.1
E2F6
E2F transcription factor 6
chr16_+_57662419 0.56 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
GPR56
G protein-coupled receptor 56
chr22_+_19466980 0.53 ENST00000407835.1
ENST00000438587.1
CDC45
cell division cycle 45
chr16_+_12059091 0.52 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr10_+_85899196 0.52 ENST00000372134.3
GHITM
growth hormone inducible transmembrane protein
chr4_-_987217 0.51 ENST00000361661.2
ENST00000398516.2
SLC26A1
solute carrier family 26 (anion exchanger), member 1
chr3_+_184038073 0.49 ENST00000428387.1
ENST00000434061.2
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr5_-_137911049 0.49 ENST00000297185.3
HSPA9
heat shock 70kDa protein 9 (mortalin)
chr19_+_34850385 0.49 ENST00000587521.2
ENST00000587384.1
ENST00000592277.1
GPI
glucose-6-phosphate isomerase
chr10_+_115312825 0.48 ENST00000537906.1
ENST00000541666.1
HABP2
hyaluronan binding protein 2
chrX_+_153769409 0.48 ENST00000440286.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr17_-_74351010 0.47 ENST00000435555.2
PRPSAP1
phosphoribosyl pyrophosphate synthetase-associated protein 1
chr12_+_10365082 0.47 ENST00000545859.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr11_-_2924970 0.47 ENST00000533594.1
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr6_+_84569359 0.47 ENST00000369681.5
ENST00000369679.4
CYB5R4
cytochrome b5 reductase 4
chr7_-_42971759 0.47 ENST00000538645.1
ENST00000445517.1
ENST00000223321.4
PSMA2
proteasome (prosome, macropain) subunit, alpha type, 2
chr6_-_28321971 0.44 ENST00000396838.2
ENST00000426434.1
ENST00000434036.1
ENST00000439628.1
ZSCAN31
zinc finger and SCAN domain containing 31
chr16_-_1429674 0.44 ENST00000403703.1
ENST00000397464.1
ENST00000402641.2
UNKL
unkempt family zinc finger-like
chr11_-_17555421 0.43 ENST00000526181.1
USH1C
Usher syndrome 1C (autosomal recessive, severe)
chr16_+_57662138 0.43 ENST00000562414.1
ENST00000561969.1
ENST00000562631.1
ENST00000563445.1
ENST00000565338.1
ENST00000567702.1
GPR56
G protein-coupled receptor 56
chr11_+_72983246 0.43 ENST00000393590.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr20_-_634000 0.43 ENST00000381962.3
SRXN1
sulfiredoxin 1
chr14_-_65409438 0.43 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr3_+_184038234 0.42 ENST00000427607.1
ENST00000457456.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr17_+_21729593 0.42 ENST00000581769.1
ENST00000584755.1
UBBP4
ubiquitin B pseudogene 4
chr9_-_113018835 0.42 ENST00000374517.5
TXN
thioredoxin
chr1_-_94374946 0.42 ENST00000370238.3
GCLM
glutamate-cysteine ligase, modifier subunit
chr5_+_179247759 0.41 ENST00000389805.4
ENST00000504627.1
ENST00000402874.3
ENST00000510187.1
SQSTM1
sequestosome 1
chr19_-_51587502 0.41 ENST00000156499.2
ENST00000391802.1
KLK14
kallikrein-related peptidase 14
chr17_+_21729899 0.41 ENST00000583708.1
UBBP4
ubiquitin B pseudogene 4
chr11_-_119066545 0.41 ENST00000415318.1
CCDC153
coiled-coil domain containing 153
chr8_+_87111059 0.40 ENST00000285393.3
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr19_-_19739321 0.40 ENST00000588461.1
LPAR2
lysophosphatidic acid receptor 2
chr12_-_57081940 0.40 ENST00000436399.2
PTGES3
prostaglandin E synthase 3 (cytosolic)
chrX_-_154563889 0.39 ENST00000369449.2
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr8_-_38386175 0.38 ENST00000437935.2
ENST00000358138.1
C8orf86
chromosome 8 open reading frame 86
chr16_+_57662527 0.38 ENST00000563374.1
ENST00000568234.1
ENST00000565770.1
ENST00000564338.1
ENST00000566164.1
GPR56
G protein-coupled receptor 56
chr19_-_39390212 0.38 ENST00000437828.1
SIRT2
sirtuin 2
chrX_+_56590002 0.37 ENST00000338222.5
UBQLN2
ubiquilin 2
chr3_+_183903811 0.37 ENST00000429586.2
ENST00000292808.5
ABCF3
ATP-binding cassette, sub-family F (GCN20), member 3
chr7_+_139529040 0.36 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr5_+_42756903 0.35 ENST00000361970.5
ENST00000388827.4
CCDC152
coiled-coil domain containing 152
chr9_-_26947220 0.34 ENST00000520884.1
PLAA
phospholipase A2-activating protein
chr9_-_86322516 0.34 ENST00000529923.1
UBQLN1
ubiquilin 1
chr1_+_26869597 0.34 ENST00000530003.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr12_+_64846129 0.34 ENST00000540417.1
ENST00000539810.1
TBK1
TANK-binding kinase 1
chr14_-_54317532 0.34 ENST00000418927.1
AL162759.1
AL162759.1
chr15_+_65914260 0.33 ENST00000261892.6
ENST00000339868.6
SLC24A1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr8_-_144413981 0.33 ENST00000522041.1
TOP1MT
topoisomerase (DNA) I, mitochondrial
chr8_-_30585294 0.33 ENST00000546342.1
ENST00000541648.1
ENST00000537535.1
GSR
glutathione reductase
chr17_-_3794021 0.32 ENST00000381769.2
CAMKK1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr12_-_58026451 0.32 ENST00000552350.1
ENST00000548888.1
B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr3_-_186262166 0.32 ENST00000307944.5
CRYGS
crystallin, gamma S
chr6_+_33378517 0.32 ENST00000428274.1
PHF1
PHD finger protein 1
chr4_+_15004165 0.31 ENST00000538197.1
ENST00000541112.1
ENST00000442003.2
CPEB2
cytoplasmic polyadenylation element binding protein 2
chr7_+_139528952 0.31 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr19_-_10613421 0.31 ENST00000393623.2
KEAP1
kelch-like ECH-associated protein 1
chr10_-_127505167 0.31 ENST00000368786.1
UROS
uroporphyrinogen III synthase
chr14_+_58711539 0.30 ENST00000216455.4
ENST00000412908.2
ENST00000557508.1
PSMA3
proteasome (prosome, macropain) subunit, alpha type, 3
chr6_-_138428613 0.30 ENST00000421351.3
PERP
PERP, TP53 apoptosis effector
chr9_-_139948468 0.30 ENST00000312665.5
ENTPD2
ectonucleoside triphosphate diphosphohydrolase 2
chr6_-_31745037 0.30 ENST00000375688.4
VWA7
von Willebrand factor A domain containing 7
chr3_-_170587815 0.30 ENST00000466674.1
RPL22L1
ribosomal protein L22-like 1
chr20_+_34742650 0.29 ENST00000373945.1
ENST00000338074.2
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr9_+_2158443 0.29 ENST00000302401.3
ENST00000324954.5
ENST00000423555.1
ENST00000382186.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr19_-_39390440 0.29 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
SIRT2
sirtuin 2
chr17_+_55162453 0.28 ENST00000575322.1
ENST00000337714.3
ENST00000314126.3
AKAP1
A kinase (PRKA) anchor protein 1
chr13_-_67802549 0.28 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr9_-_26946981 0.28 ENST00000523212.1
PLAA
phospholipase A2-activating protein
chr9_+_2158485 0.28 ENST00000417599.1
ENST00000382185.1
ENST00000382183.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr7_-_100026280 0.28 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
ZCWPW1
zinc finger, CW type with PWWP domain 1
chr3_-_56809685 0.28 ENST00000413728.2
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr22_+_21369316 0.28 ENST00000413302.2
ENST00000402329.3
ENST00000336296.2
ENST00000401443.1
ENST00000443995.3
P2RX6
purinergic receptor P2X, ligand-gated ion channel, 6
chr8_-_68658578 0.28 ENST00000518549.1
ENST00000297770.4
ENST00000297769.4
CPA6
carboxypeptidase A6
chr6_-_31745085 0.28 ENST00000375686.3
ENST00000447450.1
VWA7
von Willebrand factor A domain containing 7
chr1_-_150208320 0.27 ENST00000534220.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr1_-_160253998 0.27 ENST00000392220.2
PEX19
peroxisomal biogenesis factor 19
chr7_+_100026406 0.26 ENST00000414441.1
MEPCE
methylphosphate capping enzyme
chr17_-_5138099 0.26 ENST00000571800.1
ENST00000574081.1
ENST00000399600.4
ENST00000574297.1
SCIMP
SLP adaptor and CSK interacting membrane protein
chr2_+_74781828 0.26 ENST00000340004.6
DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr19_-_14992264 0.26 ENST00000327462.2
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chr20_+_42839722 0.26 ENST00000442383.1
ENST00000435163.1
OSER1-AS1
OSER1 antisense RNA 1 (head to head)
chrX_-_72434628 0.26 ENST00000536638.1
ENST00000373517.3
NAP1L2
nucleosome assembly protein 1-like 2
chr11_-_62474803 0.26 ENST00000533982.1
ENST00000360796.5
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr12_+_64845864 0.25 ENST00000538890.1
TBK1
TANK-binding kinase 1
chr17_+_18625336 0.25 ENST00000395671.4
ENST00000571542.1
ENST00000395672.2
ENST00000414850.2
ENST00000424146.2
TRIM16L
tripartite motif containing 16-like
chr2_+_242167319 0.25 ENST00000601871.1
AC104841.2
HCG1777198, isoform CRA_a; PRO2900; Uncharacterized protein
chr18_-_12377283 0.24 ENST00000269143.3
AFG3L2
AFG3-like AAA ATPase 2
chr3_+_184037466 0.24 ENST00000441154.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr11_-_47447970 0.24 ENST00000298852.3
ENST00000530912.1
PSMC3
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr19_+_10959043 0.24 ENST00000397820.4
C19orf38
chromosome 19 open reading frame 38
chr19_-_59023348 0.24 ENST00000601355.1
ENST00000263093.2
SLC27A5
solute carrier family 27 (fatty acid transporter), member 5
chr9_-_26947453 0.24 ENST00000397292.3
PLAA
phospholipase A2-activating protein
chr12_-_53343560 0.23 ENST00000548998.1
KRT8
keratin 8
chr21_+_33031935 0.23 ENST00000270142.6
ENST00000389995.4
SOD1
superoxide dismutase 1, soluble
chr18_+_11857439 0.23 ENST00000602628.1
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr19_+_16296191 0.23 ENST00000589852.1
ENST00000263384.7
ENST00000588367.1
ENST00000587351.1
FAM32A
family with sequence similarity 32, member A
chr2_+_18059906 0.23 ENST00000304101.4
KCNS3
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chr3_+_69134124 0.23 ENST00000478935.1
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr22_-_39268192 0.22 ENST00000216083.6
CBX6
chromobox homolog 6
chr16_-_67260901 0.22 ENST00000341546.3
ENST00000409509.1
ENST00000433915.1
ENST00000454102.2
LRRC29
AC040160.1
leucine rich repeat containing 29
Uncharacterized protein; cDNA FLJ57407, weakly similar to Mus musculus leucine rich repeat containing 29 (Lrrc29), mRNA
chr11_-_47447767 0.22 ENST00000530651.1
ENST00000524447.2
ENST00000531051.2
ENST00000526993.1
ENST00000602866.1
PSMC3
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr19_-_39390350 0.22 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
SIRT2
sirtuin 2
chr6_-_28321827 0.22 ENST00000444081.1
ZSCAN31
zinc finger and SCAN domain containing 31
chr2_+_207804278 0.22 ENST00000272852.3
CPO
carboxypeptidase O
chr3_-_170587974 0.21 ENST00000463836.1
RPL22L1
ribosomal protein L22-like 1
chr17_+_75372165 0.21 ENST00000427674.2
SEPT9
septin 9
chr7_-_86849883 0.21 ENST00000433078.1
TMEM243
transmembrane protein 243, mitochondrial
chr10_-_75173785 0.21 ENST00000535178.1
ENST00000372921.5
ENST00000372919.4
ANXA7
annexin A7
chr19_-_10613361 0.21 ENST00000591039.1
ENST00000591419.1
KEAP1
kelch-like ECH-associated protein 1
chr16_-_67260691 0.21 ENST00000447579.1
ENST00000393992.1
ENST00000424285.1
LRRC29
leucine rich repeat containing 29
chr10_-_13544945 0.21 ENST00000378605.3
ENST00000341083.3
BEND7
BEN domain containing 7
chr19_+_15751689 0.20 ENST00000586182.2
ENST00000591058.1
ENST00000221307.8
CYP4F3
cytochrome P450, family 4, subfamily F, polypeptide 3
chr3_+_46204959 0.20 ENST00000357422.2
CCR3
chemokine (C-C motif) receptor 3
chr6_-_3157760 0.20 ENST00000333628.3
TUBB2A
tubulin, beta 2A class IIa
chr17_-_61512545 0.20 ENST00000585153.1
CYB561
cytochrome b561
chr12_-_57522813 0.20 ENST00000556155.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr16_+_30418910 0.20 ENST00000566625.1
ZNF771
zinc finger protein 771
chr17_-_28618948 0.19 ENST00000261714.6
BLMH
bleomycin hydrolase
chr6_-_35888905 0.19 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRPK1
SRSF protein kinase 1
chr6_-_105585022 0.19 ENST00000314641.5
BVES
blood vessel epicardial substance
chr12_+_10365404 0.19 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr5_-_173173171 0.19 ENST00000517733.1
ENST00000518902.1
CTB-43E15.3
CTB-43E15.3
chr12_-_57082060 0.19 ENST00000448157.2
ENST00000414274.3
ENST00000262033.6
ENST00000456859.2
PTGES3
prostaglandin E synthase 3 (cytosolic)
chr2_-_11606275 0.19 ENST00000381525.3
ENST00000362009.4
E2F6
E2F transcription factor 6
chr7_+_42971799 0.19 ENST00000223324.2
MRPL32
mitochondrial ribosomal protein L32
chr8_-_101348408 0.19 ENST00000519527.1
ENST00000522369.1
RNF19A
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr11_-_18656028 0.19 ENST00000336349.5
SPTY2D1
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr12_-_53343602 0.18 ENST00000546897.1
ENST00000552551.1
KRT8
keratin 8
chr18_-_55253830 0.18 ENST00000591215.1
FECH
ferrochelatase
chr15_+_59903975 0.18 ENST00000560585.1
ENST00000396065.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr1_+_229440129 0.18 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr1_-_150208291 0.18 ENST00000533654.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chrX_+_22056165 0.18 ENST00000535894.1
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr1_-_150208498 0.18 ENST00000314136.8
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr1_-_65533390 0.18 ENST00000448344.1
RP4-535B20.1
RP4-535B20.1
chr12_-_10826612 0.17 ENST00000535345.1
ENST00000542562.1
STYK1
serine/threonine/tyrosine kinase 1
chr2_+_219125714 0.17 ENST00000522678.1
ENST00000519574.1
ENST00000521462.1
GPBAR1
G protein-coupled bile acid receptor 1
chr11_-_47207390 0.17 ENST00000539589.1
ENST00000528462.1
PACSIN3
protein kinase C and casein kinase substrate in neurons 3
chr12_-_51611477 0.17 ENST00000389243.4
POU6F1
POU class 6 homeobox 1
chr7_-_110174754 0.17 ENST00000435466.1
AC003088.1
AC003088.1
chr7_+_145813453 0.16 ENST00000361727.3
CNTNAP2
contactin associated protein-like 2
chr16_-_28222797 0.16 ENST00000569951.1
ENST00000565698.1
XPO6
exportin 6
chr20_-_42839378 0.16 ENST00000255174.2
OSER1
oxidative stress responsive serine-rich 1
chr17_+_7344057 0.16 ENST00000575398.1
ENST00000575082.1
FGF11
fibroblast growth factor 11
chr14_-_95942173 0.16 ENST00000334258.5
ENST00000557275.1
ENST00000553340.1
SYNE3
spectrin repeat containing, nuclear envelope family member 3
chr19_-_46142362 0.16 ENST00000586770.1
ENST00000591721.1
EML2
echinoderm microtubule associated protein like 2
chr1_-_150208412 0.16 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr20_+_42839600 0.16 ENST00000439943.1
ENST00000437730.1
OSER1-AS1
OSER1 antisense RNA 1 (head to head)
chr1_-_150208363 0.16 ENST00000436748.2
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chrX_+_99899180 0.16 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr6_+_44215603 0.15 ENST00000371554.1
HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr2_+_122513109 0.15 ENST00000389682.3
ENST00000536142.1
TSN
translin
chr16_-_30125177 0.15 ENST00000406256.3
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr4_-_76944621 0.15 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr2_-_220173685 0.15 ENST00000423636.2
ENST00000442029.1
ENST00000412847.1
PTPRN
protein tyrosine phosphatase, receptor type, N
chr19_+_35820064 0.15 ENST00000341773.6
ENST00000600131.1
ENST00000270311.6
ENST00000595780.1
ENST00000597916.1
ENST00000593867.1
ENST00000600424.1
ENST00000599811.1
ENST00000536635.2
ENST00000085219.5
ENST00000544992.2
ENST00000419549.2
CD22
CD22 molecule

Network of associatons between targets according to the STRING database.

First level regulatory network of BACH1_NFE2_NFE2L2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.4 2.5 GO:0070541 response to platinum ion(GO:0070541)
0.3 0.9 GO:0061433 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.3 0.8 GO:0016488 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
0.2 1.8 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.2 2.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.2 0.5 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 0.5 GO:0003032 detection of oxygen(GO:0003032)
0.1 0.7 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.5 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 0.4 GO:1904106 protein localization to microvillus(GO:1904106)
0.1 0.4 GO:1904387 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.1 0.5 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.7 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.1 0.3 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 1.1 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.1 0.5 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.1 1.8 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.4 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.3 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 1.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 1.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.2 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 0.6 GO:2001268 positive regulation of keratinocyte migration(GO:0051549) negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1 1.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.2 GO:0060931 sinoatrial node cell development(GO:0060931)
0.1 0.1 GO:0060168 regulation of adenosine receptor signaling pathway(GO:0060167) positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.1 0.2 GO:0071109 superior temporal gyrus development(GO:0071109)
0.1 0.3 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.6 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.2 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.4 GO:0043418 homocysteine catabolic process(GO:0043418)
0.0 0.4 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.3 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.2 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 1.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.3 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.2 GO:0036101 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.0 0.7 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.4 GO:0007320 insemination(GO:0007320)
0.0 0.4 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.2 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.3 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442) regulation of stem cell division(GO:2000035)
0.0 0.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.2 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.6 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.1 GO:0090410 malonate catabolic process(GO:0090410)
0.0 0.2 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.3 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.2 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0070340 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.0 2.1 GO:0043276 anoikis(GO:0043276)
0.0 0.8 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.3 GO:0040031 snRNA modification(GO:0040031)
0.0 0.5 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.2 GO:0038183 bile acid signaling pathway(GO:0038183)
0.0 0.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.2 GO:2001205 TNFSF11-mediated signaling pathway(GO:0071847) negative regulation of osteoclast development(GO:2001205)
0.0 0.4 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.1 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
0.0 0.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.3 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.8 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.1 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.2 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043281)
0.0 0.3 GO:0002934 desmosome organization(GO:0002934)
0.0 0.1 GO:0060356 leucine import(GO:0060356)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 1.0 GO:0043486 histone exchange(GO:0043486)
0.0 0.3 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.6 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.1 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.4 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.7 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.0 GO:0070839 divalent metal ion export(GO:0070839)
0.0 0.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.1 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.0 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.1 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.0 GO:2000116 regulation of cysteine-type endopeptidase activity(GO:2000116)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.4 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.0 GO:1902499 regulation of protein autoubiquitination(GO:1902498) positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.3 GO:0009642 response to light intensity(GO:0009642)
0.0 0.6 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.8 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.2 0.5 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 0.4 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.4 GO:0044753 amphisome(GO:0044753)
0.1 2.0 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.2 GO:0005745 m-AAA complex(GO:0005745)
0.1 0.9 GO:0072687 meiotic spindle(GO:0072687)
0.1 0.7 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1.8 GO:0031932 TORC2 complex(GO:0031932)
0.1 1.1 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 0.9 GO:0000812 Swr1 complex(GO:0000812)
0.0 1.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.6 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.5 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 1.0 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.3 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.4 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.8 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.2 GO:0033010 paranodal junction(GO:0033010)
0.0 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.6 GO:0001533 cornified envelope(GO:0001533)
0.0 2.5 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0019862 IgA binding(GO:0019862)
0.6 2.5 GO:0004325 ferrochelatase activity(GO:0004325)
0.4 2.0 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.4 2.1 GO:0070026 nitric oxide binding(GO:0070026)
0.3 0.9 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.3 0.8 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955)
0.3 0.8 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
0.3 0.8 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.2 0.7 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.2 0.9 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.2 0.6 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.2 0.7 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.6 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 0.7 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.6 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.4 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 1.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.7 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.3 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 0.5 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.1 0.5 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.4 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.1 0.2 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 0.7 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 1.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.8 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.2 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 0.5 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.2 GO:0032551 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.1 1.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 0.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.5 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.0 0.4 GO:0071553 uridine nucleotide receptor activity(GO:0015065) UDP-activated nucleotide receptor activity(GO:0045029) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.0 0.1 GO:0090409 malonyl-CoA synthetase activity(GO:0090409)
0.0 0.1 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.5 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.2 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.3 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.3 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.1 GO:0019828 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.5 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.0 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.0 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.4 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 2.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.2 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 1.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 2.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 2.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.5 PID E2F PATHWAY E2F transcription factor network
0.0 0.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 2.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 0.8 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 1.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.4 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.6 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.7 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events