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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for BHLHE22_BHLHA15_BHLHE23

Z-value: 1.22

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Transcription factors associated with BHLHE22_BHLHA15_BHLHE23

Gene Symbol Gene ID Gene Info
BHLHE22
ENSG00000180828.1 basic helix-loop-helix family member e22
BHLHA15
ENSG00000180535.3 basic helix-loop-helix family member a15
BHLHE23
ENSG00000125533.4 basic helix-loop-helix family member e23

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BHLHA15hg19_v2_chr7_+_97840739_978407860.722.8e-01Click!
BHLHE22hg19_v2_chr8_+_65492756_654928140.406.0e-01Click!

Activity profile of BHLHE22_BHLHA15_BHLHE23 motif

Sorted Z-values of BHLHE22_BHLHA15_BHLHE23 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_32414059 5.64 ENST00000553330.1
RP11-187E13.1
Uncharacterized protein
chr16_-_69385681 1.65 ENST00000288025.3
TMED6
transmembrane emp24 protein transport domain containing 6
chr3_-_121379739 1.48 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr1_+_81106951 1.42 ENST00000443565.1
RP5-887A10.1
RP5-887A10.1
chr12_-_94673956 1.31 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr1_+_186344883 1.31 ENST00000367470.3
C1orf27
chromosome 1 open reading frame 27
chr15_-_98417780 1.23 ENST00000503874.3
LINC00923
long intergenic non-protein coding RNA 923
chr5_-_114632307 1.12 ENST00000506442.1
ENST00000379611.5
CCDC112
coiled-coil domain containing 112
chr1_+_186344945 1.01 ENST00000419367.3
ENST00000287859.6
C1orf27
chromosome 1 open reading frame 27
chr5_-_114631958 0.91 ENST00000395557.4
CCDC112
coiled-coil domain containing 112
chr14_-_107283278 0.87 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr10_+_89124746 0.77 ENST00000465545.1
NUTM2D
NUT family member 2D
chr13_+_28813645 0.76 ENST00000282391.5
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr2_-_182545603 0.73 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr15_-_38519066 0.70 ENST00000561320.1
ENST00000561161.1
RP11-346D14.1
RP11-346D14.1
chr3_-_129375556 0.68 ENST00000510323.1
TMCC1
transmembrane and coiled-coil domain family 1
chr8_+_67782984 0.66 ENST00000396592.3
ENST00000422365.2
ENST00000492775.1
MCMDC2
minichromosome maintenance domain containing 2
chr19_+_42041860 0.62 ENST00000483481.2
ENST00000494375.2
AC006129.4
AC006129.4
chr15_-_55700216 0.58 ENST00000569205.1
CCPG1
cell cycle progression 1
chrX_-_84363974 0.52 ENST00000395409.3
ENST00000332921.5
ENST00000509231.1
SATL1
spermidine/spermine N1-acetyl transferase-like 1
chr7_+_116502605 0.51 ENST00000458284.2
ENST00000490693.1
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr1_-_186344802 0.48 ENST00000451586.1
TPR
translocated promoter region, nuclear basket protein
chr12_-_91573132 0.46 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr3_-_197300194 0.45 ENST00000358186.2
ENST00000431056.1
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr17_+_7211656 0.45 ENST00000416016.2
EIF5A
eukaryotic translation initiation factor 5A
chr15_-_55700522 0.43 ENST00000564092.1
ENST00000310958.6
CCPG1
cell cycle progression 1
chr4_-_74088800 0.43 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr11_+_120107344 0.42 ENST00000260264.4
POU2F3
POU class 2 homeobox 3
chr8_+_35649365 0.42 ENST00000437887.1
AC012215.1
Uncharacterized protein
chr22_+_20877924 0.40 ENST00000445189.1
MED15
mediator complex subunit 15
chr15_-_65503801 0.39 ENST00000261883.4
CILP
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr15_-_55700457 0.39 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
CCPG1
cell cycle progression 1
chr15_-_63448973 0.38 ENST00000462430.1
RPS27L
ribosomal protein S27-like
chr3_+_112930306 0.37 ENST00000495514.1
BOC
BOC cell adhesion associated, oncogene regulated
chr7_-_101212244 0.36 ENST00000451953.1
ENST00000434537.1
ENST00000437900.1
LINC01007
long intergenic non-protein coding RNA 1007
chr17_+_39846114 0.34 ENST00000586699.1
EIF1
eukaryotic translation initiation factor 1
chr4_-_159094194 0.33 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B
family with sequence similarity 198, member B
chr7_-_48068643 0.32 ENST00000453192.2
SUN3
Sad1 and UNC84 domain containing 3
chr8_-_38239732 0.32 ENST00000534155.1
ENST00000433384.2
ENST00000317025.8
ENST00000316985.3
WHSC1L1
Wolf-Hirschhorn syndrome candidate 1-like 1
chr3_+_62304648 0.31 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
C3orf14
chromosome 3 open reading frame 14
chr11_-_26743546 0.31 ENST00000280467.6
ENST00000396005.3
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr4_+_55095428 0.31 ENST00000508170.1
ENST00000512143.1
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr6_-_108278456 0.30 ENST00000429168.1
SEC63
SEC63 homolog (S. cerevisiae)
chrX_+_107334895 0.29 ENST00000372232.3
ENST00000345734.3
ENST00000372254.3
ATG4A
autophagy related 4A, cysteine peptidase
chr19_+_42041702 0.29 ENST00000487420.2
AC006129.4
AC006129.4
chrX_-_15402498 0.29 ENST00000297904.3
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr9_+_2158485 0.28 ENST00000417599.1
ENST00000382185.1
ENST00000382183.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr12_+_79371565 0.27 ENST00000551304.1
SYT1
synaptotagmin I
chr5_+_135496675 0.26 ENST00000507637.1
SMAD5
SMAD family member 5
chr7_-_99573677 0.26 ENST00000292401.4
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr17_-_31404 0.26 ENST00000343572.7
DOC2B
double C2-like domains, beta
chr8_+_21823726 0.26 ENST00000433566.4
XPO7
exportin 7
chr3_-_114477962 0.25 ENST00000471418.1
ZBTB20
zinc finger and BTB domain containing 20
chr3_+_185300270 0.24 ENST00000430355.1
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr9_+_2158443 0.24 ENST00000302401.3
ENST00000324954.5
ENST00000423555.1
ENST00000382186.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr8_-_101724989 0.24 ENST00000517403.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr5_+_173316341 0.23 ENST00000520867.1
ENST00000334035.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr2_-_32490801 0.23 ENST00000360906.5
ENST00000342905.6
NLRC4
NLR family, CARD domain containing 4
chr2_-_228582709 0.22 ENST00000541617.1
ENST00000409456.2
ENST00000409287.1
ENST00000258403.3
SLC19A3
solute carrier family 19 (thiamine transporter), member 3
chr9_+_18474098 0.22 ENST00000327883.7
ENST00000431052.2
ENST00000380570.4
ADAMTSL1
ADAMTS-like 1
chr11_+_66008698 0.22 ENST00000531597.1
PACS1
phosphofurin acidic cluster sorting protein 1
chr7_+_116502527 0.21 ENST00000361183.3
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr17_+_75316336 0.21 ENST00000591934.1
SEPT9
septin 9
chrX_+_107334983 0.21 ENST00000457035.1
ENST00000545696.1
ATG4A
autophagy related 4A, cysteine peptidase
chr10_-_69597810 0.21 ENST00000483798.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr15_+_65843130 0.21 ENST00000569894.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr1_+_185126598 0.20 ENST00000450350.1
SWT1
SWT1 RNA endoribonuclease homolog (S. cerevisiae)
chr1_+_159272111 0.20 ENST00000368114.1
FCER1A
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
chr3_+_75713481 0.20 ENST00000308062.3
ENST00000464571.1
FRG2C
FSHD region gene 2 family, member C
chrX_+_70798261 0.19 ENST00000373696.3
ACRC
acidic repeat containing
chr2_+_108994466 0.18 ENST00000272452.2
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr1_+_110881945 0.18 ENST00000602849.1
ENST00000487146.2
RBM15
RNA binding motif protein 15
chr10_-_94257512 0.18 ENST00000371581.5
IDE
insulin-degrading enzyme
chr3_+_46924829 0.17 ENST00000313049.5
PTH1R
parathyroid hormone 1 receptor
chr1_-_98515395 0.17 ENST00000424528.2
MIR137HG
MIR137 host gene (non-protein coding)
chr2_-_188378368 0.17 ENST00000392365.1
ENST00000435414.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chrX_+_69509870 0.17 ENST00000374388.3
KIF4A
kinesin family member 4A
chr4_+_2814011 0.16 ENST00000502260.1
ENST00000435136.2
SH3BP2
SH3-domain binding protein 2
chr20_+_57226841 0.16 ENST00000358029.4
ENST00000361830.3
STX16
syntaxin 16
chr10_-_15902449 0.15 ENST00000277632.3
FAM188A
family with sequence similarity 188, member A
chr21_-_36421401 0.15 ENST00000486278.2
RUNX1
runt-related transcription factor 1
chr3_-_114477787 0.15 ENST00000464560.1
ZBTB20
zinc finger and BTB domain containing 20
chr8_-_67976509 0.14 ENST00000518747.1
COPS5
COP9 signalosome subunit 5
chr2_+_105471969 0.14 ENST00000361360.2
POU3F3
POU class 3 homeobox 3
chr17_-_56492989 0.13 ENST00000583753.1
RNF43
ring finger protein 43
chr4_+_2813946 0.13 ENST00000442312.2
SH3BP2
SH3-domain binding protein 2
chr8_+_67976593 0.13 ENST00000262210.5
ENST00000412460.1
CSPP1
centrosome and spindle pole associated protein 1
chr4_+_25915896 0.13 ENST00000514384.1
SMIM20
small integral membrane protein 20
chr20_+_33292507 0.13 ENST00000414082.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr6_-_119031228 0.12 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L
centrosomal protein 85kDa-like
chr4_-_153456153 0.12 ENST00000603548.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr8_-_23315190 0.12 ENST00000356206.6
ENST00000358689.4
ENST00000417069.2
ENTPD4
ectonucleoside triphosphate diphosphohydrolase 4
chrX_+_69509927 0.12 ENST00000374403.3
KIF4A
kinesin family member 4A
chr19_-_11450249 0.12 ENST00000222120.3
RAB3D
RAB3D, member RAS oncogene family
chr19_+_18208603 0.10 ENST00000262811.6
MAST3
microtubule associated serine/threonine kinase 3
chr11_-_44972418 0.10 ENST00000525680.1
ENST00000528290.1
ENST00000530035.1
TP53I11
tumor protein p53 inducible protein 11
chr9_+_125796806 0.10 ENST00000373642.1
GPR21
G protein-coupled receptor 21
chr2_+_181845843 0.10 ENST00000602710.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr5_-_159766528 0.10 ENST00000505287.2
CCNJL
cyclin J-like
chr16_-_52640834 0.10 ENST00000510238.3
CASC16
cancer susceptibility candidate 16 (non-protein coding)
chr4_-_113207048 0.09 ENST00000361717.3
TIFA
TRAF-interacting protein with forkhead-associated domain
chr7_+_107531580 0.09 ENST00000537148.1
ENST00000440410.1
ENST00000437604.2
DLD
dihydrolipoamide dehydrogenase
chr8_+_62747349 0.09 ENST00000517953.1
ENST00000520097.1
ENST00000519766.1
RP11-705O24.1
RP11-705O24.1
chr5_+_157158205 0.09 ENST00000231198.7
THG1L
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr1_+_47489240 0.09 ENST00000371901.3
CYP4X1
cytochrome P450, family 4, subfamily X, polypeptide 1
chr1_-_44818599 0.08 ENST00000537474.1
ERI3
ERI1 exoribonuclease family member 3
chr12_+_58166370 0.08 ENST00000300209.8
METTL21B
methyltransferase like 21B
chr14_-_51297837 0.08 ENST00000245441.5
ENST00000389868.3
ENST00000382041.3
ENST00000324330.9
ENST00000453196.1
ENST00000453401.2
NIN
ninein (GSK3B interacting protein)
chr12_+_58166431 0.08 ENST00000333012.5
METTL21B
methyltransferase like 21B
chr11_-_62359027 0.07 ENST00000494385.1
ENST00000308436.7
TUT1
terminal uridylyl transferase 1, U6 snRNA-specific
chr2_-_227050079 0.07 ENST00000423838.1
AC068138.1
AC068138.1
chr12_+_50794592 0.07 ENST00000293618.8
ENST00000429001.3
ENST00000548174.1
ENST00000548697.1
ENST00000548993.1
ENST00000398473.2
ENST00000522085.1
ENST00000518444.1
ENST00000551886.1
LARP4
La ribonucleoprotein domain family, member 4
chr14_-_69864993 0.06 ENST00000555373.1
ERH
enhancer of rudimentary homolog (Drosophila)
chr3_-_33700589 0.06 ENST00000461133.3
ENST00000496954.2
CLASP2
cytoplasmic linker associated protein 2
chr7_-_112758665 0.06 ENST00000397764.3
LINC00998
long intergenic non-protein coding RNA 998
chr6_+_4087664 0.05 ENST00000430835.2
C6orf201
chromosome 6 open reading frame 201
chr8_-_23315131 0.05 ENST00000518718.1
ENTPD4
ectonucleoside triphosphate diphosphohydrolase 4
chr14_+_24540154 0.05 ENST00000559778.1
ENST00000560761.1
ENST00000557889.1
CPNE6
copine VI (neuronal)
chrX_+_120181457 0.05 ENST00000328078.1
GLUD2
glutamate dehydrogenase 2
chr2_+_234637754 0.04 ENST00000482026.1
ENST00000609767.1
UGT1A3
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A3
UDP glucuronosyltransferase 1 family, polypeptide A8
chr3_-_33700933 0.04 ENST00000480013.1
CLASP2
cytoplasmic linker associated protein 2
chr3_+_185300391 0.04 ENST00000545472.1
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr14_-_51297197 0.04 ENST00000382043.4
NIN
ninein (GSK3B interacting protein)
chr2_+_99953816 0.04 ENST00000289371.6
EIF5B
eukaryotic translation initiation factor 5B
chr9_+_108424738 0.04 ENST00000334077.3
TAL2
T-cell acute lymphocytic leukemia 2
chr19_-_52227221 0.04 ENST00000222115.1
ENST00000540069.2
HAS1
hyaluronan synthase 1
chr2_+_181845763 0.03 ENST00000602499.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr12_-_95397442 0.03 ENST00000547157.1
ENST00000547986.1
ENST00000327772.2
NDUFA12
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr10_-_74114714 0.03 ENST00000338820.3
ENST00000394903.2
ENST00000444643.2
DNAJB12
DnaJ (Hsp40) homolog, subfamily B, member 12
chr1_+_104293028 0.03 ENST00000370079.3
AMY1C
amylase, alpha 1C (salivary)
chr9_+_12775011 0.03 ENST00000319264.3
LURAP1L
leucine rich adaptor protein 1-like
chr15_+_85144217 0.02 ENST00000540936.1
ENST00000448803.2
ENST00000546275.1
ENST00000546148.1
ENST00000442073.3
ENST00000334141.3
ENST00000358472.3
ENST00000502939.2
ENST00000379358.3
ENST00000327179.6
ZSCAN2
zinc finger and SCAN domain containing 2
chr17_-_9725388 0.02 ENST00000399363.4
RP11-477N12.3
Putative germ cell-specific gene 1-like protein 2
chr1_-_99470368 0.02 ENST00000263177.4
LPPR5
Lipid phosphate phosphatase-related protein type 5
chr8_+_38239882 0.02 ENST00000607047.1
RP11-350N15.5
RP11-350N15.5
chr12_+_50794947 0.02 ENST00000552445.1
LARP4
La ribonucleoprotein domain family, member 4
chr4_+_114214125 0.02 ENST00000509550.1
ANK2
ankyrin 2, neuronal
chr14_-_51297360 0.01 ENST00000496749.1
NIN
ninein (GSK3B interacting protein)
chr3_-_55515202 0.01 ENST00000482079.1
WNT5A
wingless-type MMTV integration site family, member 5A
chr3_-_150264272 0.01 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
SERP1
stress-associated endoplasmic reticulum protein 1
chr3_+_119298429 0.01 ENST00000478927.1
ADPRH
ADP-ribosylarginine hydrolase
chr17_+_44790515 0.01 ENST00000576346.1
NSF
N-ethylmaleimide-sensitive factor
chr2_-_183387430 0.01 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr1_+_61330931 0.01 ENST00000371191.1
NFIA
nuclear factor I/A
chr11_-_44972476 0.01 ENST00000527685.1
ENST00000308212.5
TP53I11
tumor protein p53 inducible protein 11
chr11_+_32154200 0.01 ENST00000525133.1
RP1-65P5.5
RP1-65P5.5
chr10_+_51565108 0.01 ENST00000438493.1
ENST00000452682.1
NCOA4
nuclear receptor coactivator 4
chr10_+_51565188 0.00 ENST00000430396.2
ENST00000374087.4
ENST00000414907.2
NCOA4
nuclear receptor coactivator 4
chr1_-_205091115 0.00 ENST00000264515.6
ENST00000367164.1
RBBP5
retinoblastoma binding protein 5
chr16_+_21716284 0.00 ENST00000388957.3
OTOA
otoancorin
chr3_-_196910721 0.00 ENST00000443183.1
DLG1
discs, large homolog 1 (Drosophila)
chr4_-_87028478 0.00 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chr6_+_31887761 0.00 ENST00000413154.1
C2
complement component 2

Network of associatons between targets according to the STRING database.

First level regulatory network of BHLHE22_BHLHA15_BHLHE23

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.2 1.4 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 0.7 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.2 0.5 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.2 0.5 GO:0045799 negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.1 1.6 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.3 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.5 GO:0051697 protein delipidation(GO:0051697)
0.1 0.4 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.8 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.2 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.1 0.5 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.2 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.3 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.0 0.2 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.2 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0 0.4 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.3 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.3 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.1 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0072240 ascending thin limb development(GO:0072021) distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric ascending thin limb development(GO:0072218) metanephric distal convoluted tubule development(GO:0072221) metanephric DCT cell differentiation(GO:0072240)
0.0 0.2 GO:0070269 pyroptosis(GO:0070269)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.4 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.3 GO:0035562 protein desumoylation(GO:0016926) regulation of DNA endoreduplication(GO:0032875) negative regulation of chromatin binding(GO:0035562) DNA endoreduplication(GO:0042023)
0.0 0.7 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.3 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0031251 PAN complex(GO:0031251)
0.1 0.5 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.2 GO:0097636 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.0 0.7 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.2 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0098576 lumenal side of membrane(GO:0098576)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0004145 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.1 0.5 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.2 GO:0031626 beta-endorphin binding(GO:0031626)
0.1 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.4 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.2 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.2 GO:0019863 IgE binding(GO:0019863)
0.0 0.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.3 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.6 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 1.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.5 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.0 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.1 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.3 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression