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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for CDX1

Z-value: 1.18

Motif logo

Transcription factors associated with CDX1

Gene Symbol Gene ID Gene Info
ENSG00000113722.12 caudal type homeobox 1

Activity profile of CDX1 motif

Sorted Z-values of CDX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_90712520 1.45 ENST00000224784.6
actin, alpha 2, smooth muscle, aorta
chr14_+_88490894 0.96 ENST00000556033.1
ENST00000553929.1
ENST00000555996.1
ENST00000556673.1
ENST00000557339.1
ENST00000556684.1
long intergenic non-protein coding RNA 1146
chr2_-_44550441 0.94 ENST00000420756.1
ENST00000444696.1
prolyl endopeptidase-like
chr3_-_148939598 0.91 ENST00000455472.3
ceruloplasmin (ferroxidase)
chr1_+_241695670 0.86 ENST00000366557.4
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr17_-_57229155 0.86 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr4_-_110723335 0.80 ENST00000394634.2
complement factor I
chr1_-_197036364 0.76 ENST00000367412.1
coagulation factor XIII, B polypeptide
chr2_+_161993465 0.75 ENST00000457476.1
TRAF family member-associated NFKB activator
chr7_-_16840820 0.75 ENST00000450569.1
anterior gradient 2
chr7_-_35013217 0.74 ENST00000446375.1
dpy-19-like 1 (C. elegans)
chr3_+_149192475 0.68 ENST00000465758.1
transmembrane 4 L six family member 4
chr4_-_110723194 0.68 ENST00000394635.3
complement factor I
chr21_+_17909594 0.64 ENST00000441820.1
ENST00000602280.1
long intergenic non-protein coding RNA 478
chr1_+_212475148 0.63 ENST00000537030.3
protein phosphatase 2, regulatory subunit B', alpha
chr16_+_2014993 0.63 ENST00000564014.1
small nucleolar RNA host gene 9 (non-protein coding)
chr10_-_69597915 0.62 ENST00000225171.2
DnaJ (Hsp40) homolog, subfamily C, member 12
chr18_+_3466248 0.62 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
chr15_-_45670924 0.60 ENST00000396659.3
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr9_-_69229650 0.58 ENST00000416428.1
COBW domain containing 6
chr19_+_38880695 0.57 ENST00000587947.1
ENST00000338502.4
sprouty-related, EVH1 domain containing 3
chr6_+_26087509 0.57 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
hemochromatosis
chr3_-_149095652 0.57 ENST00000305366.3
transmembrane 4 L six family member 1
chrX_-_80377118 0.53 ENST00000373250.3
high mobility group nucleosome binding domain 5
chr10_-_69597828 0.52 ENST00000339758.7
DnaJ (Hsp40) homolog, subfamily C, member 12
chr1_-_111970353 0.51 ENST00000369732.3
oviductal glycoprotein 1, 120kDa
chr10_-_69597810 0.51 ENST00000483798.2
DnaJ (Hsp40) homolog, subfamily C, member 12
chr12_-_91573132 0.50 ENST00000550563.1
ENST00000546370.1
decorin
chr9_-_3469181 0.50 ENST00000366116.2
Uncharacterized protein
chr8_-_95220775 0.49 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
cadherin 17, LI cadherin (liver-intestine)
chr5_+_75904950 0.49 ENST00000502745.1
IQ motif containing GTPase activating protein 2
chr9_+_125795788 0.49 ENST00000373643.5
RAB GTPase activating protein 1
chr17_-_57232596 0.49 ENST00000581068.1
ENST00000330137.7
spindle and kinetochore associated complex subunit 2
chr7_-_7679633 0.49 ENST00000401447.1
replication protein A3, 14kDa
chr6_+_63921351 0.48 ENST00000370659.1
FK506 binding protein 1C
chr4_-_110723134 0.47 ENST00000510800.1
ENST00000512148.1
complement factor I
chr2_+_33359687 0.46 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
latent transforming growth factor beta binding protein 1
chr6_+_126661253 0.45 ENST00000368326.1
ENST00000368325.1
ENST00000368328.4
centromere protein W
chr5_+_95997918 0.44 ENST00000395812.2
ENST00000395813.1
ENST00000359176.4
ENST00000325674.7
calpastatin
chr2_+_33359646 0.43 ENST00000390003.4
ENST00000418533.2
latent transforming growth factor beta binding protein 1
chr12_-_371994 0.41 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
solute carrier family 6 (neurotransmitter transporter), member 13
chr21_-_35773370 0.41 ENST00000410005.1
chromosome 21 open reading frame 140
chr10_-_126480381 0.40 ENST00000368836.2
methyltransferase like 10
chr2_+_132479948 0.40 ENST00000355171.4
chromosome 2 open reading frame 27A
chr2_+_242289502 0.38 ENST00000451310.1
septin 2
chr20_-_17539456 0.38 ENST00000544874.1
ENST00000377868.2
beaded filament structural protein 1, filensin
chr9_-_107754034 0.37 ENST00000457720.1
RP11-217B7.3
chr11_+_107992243 0.37 ENST00000265838.4
ENST00000299355.6
acetyl-CoA acetyltransferase 1
chr1_-_207095324 0.36 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
Fas apoptotic inhibitory molecule 3
chr14_+_58797974 0.36 ENST00000417477.2
AT rich interactive domain 4A (RBP1-like)
chr8_-_103876383 0.36 ENST00000347770.4
antizyme inhibitor 1
chr6_-_43423308 0.36 ENST00000372485.1
ENST00000372488.3
delta-like 2 homolog (Drosophila)
chrY_+_14958970 0.36 ENST00000453031.1
ubiquitin specific peptidase 9, Y-linked
chr15_-_55700457 0.35 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
cell cycle progression 1
chr9_-_97356075 0.35 ENST00000375337.3
fructose-1,6-bisphosphatase 2
chr17_-_48943706 0.35 ENST00000499247.2
transducer of ERBB2, 1
chr15_+_89164520 0.35 ENST00000332810.3
apoptosis enhancing nuclease
chr15_+_69857515 0.35 ENST00000559477.1
RP11-279F6.1
chr17_+_57233087 0.34 ENST00000578777.1
ENST00000577457.1
ENST00000582995.1
proline rich 11
chr10_-_38146965 0.34 ENST00000395873.3
ENST00000357328.4
ENST00000395874.2
zinc finger protein 248
chr1_-_15911510 0.34 ENST00000375826.3
agmatine ureohydrolase (agmatinase)
chr18_-_29264467 0.34 ENST00000383131.3
ENST00000237019.7
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr14_+_102276192 0.33 ENST00000557714.1
protein phosphatase 2, regulatory subunit B', gamma
chr1_+_150254936 0.33 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
chromosome 1 open reading frame 51
chr2_+_196521458 0.32 ENST00000409086.3
solute carrier family 39 (zinc transporter), member 10
chr15_-_45670717 0.32 ENST00000558163.1
ENST00000558336.1
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr6_+_26087646 0.32 ENST00000309234.6
hemochromatosis
chr22_+_25595817 0.32 ENST00000215855.2
ENST00000404334.1
crystallin, beta B3
chr21_+_17214724 0.31 ENST00000449491.1
ubiquitin specific peptidase 25
chr18_+_61575200 0.31 ENST00000238508.3
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr16_+_56672571 0.31 ENST00000290705.8
metallothionein 1A
chr12_-_76461249 0.31 ENST00000551524.1
nucleosome assembly protein 1-like 1
chr12_-_90049878 0.31 ENST00000359142.3
ATPase, Ca++ transporting, plasma membrane 1
chr2_+_161993412 0.31 ENST00000259075.2
ENST00000432002.1
TRAF family member-associated NFKB activator
chr17_-_56492989 0.30 ENST00000583753.1
ring finger protein 43
chr7_+_23210760 0.30 ENST00000366347.4
Uncharacterized protein
chr8_-_125551278 0.30 ENST00000519232.1
ENST00000523888.1
ENST00000522810.1
ENST00000519548.1
ENST00000517678.1
ENST00000605953.1
ENST00000276692.6
TatD DNase domain containing 1
chr8_+_76452097 0.30 ENST00000396423.2
hepatocyte nuclear factor 4, gamma
chr15_-_83474806 0.30 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
fibronectin type III and SPRY domain containing 2
chr1_-_40042416 0.30 ENST00000372857.3
ENST00000372856.3
ENST00000531243.2
ENST00000451091.2
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr12_+_16500037 0.29 ENST00000536371.1
ENST00000010404.2
microsomal glutathione S-transferase 1
chr13_+_53030107 0.29 ENST00000490903.1
ENST00000480747.1
cytoskeleton associated protein 2
chr11_-_4719072 0.29 ENST00000396950.3
ENST00000532598.1
olfactory receptor, family 51, subfamily E, member 2
chr9_+_124088860 0.29 ENST00000373806.1
gelsolin
chr8_+_35649365 0.29 ENST00000437887.1
Uncharacterized protein
chr19_+_46367518 0.28 ENST00000302177.2
forkhead box A3
chr7_+_90012986 0.28 ENST00000416322.1
claudin 12
chr17_+_57232690 0.28 ENST00000262293.4
proline rich 11
chr3_-_96337000 0.28 ENST00000600213.2
MT-RNR2-like 12 (pseudogene)
chr16_-_18887627 0.28 ENST00000563235.1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr7_+_151722712 0.28 ENST00000430044.2
ENST00000431668.1
ENST00000446096.1
ENST00000452146.2
ENST00000423337.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr12_+_28410128 0.28 ENST00000381259.1
ENST00000381256.1
coiled-coil domain containing 91
chr1_-_193075180 0.28 ENST00000367440.3
glutaredoxin 2
chr5_+_75904918 0.27 ENST00000514001.1
ENST00000396234.3
ENST00000509074.1
IQ motif containing GTPase activating protein 2
chr8_-_117886955 0.27 ENST00000297338.2
RAD21 homolog (S. pombe)
chr13_-_114107839 0.27 ENST00000375418.3
ADP-ribosylhydrolase like 1
chr18_+_47901408 0.27 ENST00000398452.2
ENST00000417656.2
ENST00000488454.1
ENST00000494518.1
spindle and kinetochore associated complex subunit 1
chr3_-_193096600 0.27 ENST00000446087.1
ENST00000342358.4
ATPase type 13A5
chr16_-_11876408 0.27 ENST00000396516.2
zinc finger CCCH-type containing 7A
chr8_+_93895865 0.26 ENST00000391681.1
AC117834.1
chr11_+_73003824 0.26 ENST00000538328.1
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr3_+_45636219 0.26 ENST00000273317.4
LIM domains containing 1
chr2_-_224467093 0.26 ENST00000305409.2
secretogranin II
chr10_+_112327425 0.26 ENST00000361804.4
structural maintenance of chromosomes 3
chr17_+_41005283 0.26 ENST00000592999.1
amine oxidase, copper containing 3
chrX_-_45629661 0.25 ENST00000602507.1
ENST00000602461.1
RP6-99M1.2
chr5_+_96079240 0.25 ENST00000515663.1
calpastatin
chr7_+_37723450 0.25 ENST00000447769.1
G protein-coupled receptor 141
chr7_-_11871815 0.25 ENST00000423059.4
thrombospondin, type I, domain containing 7A
chr18_+_47901365 0.25 ENST00000285116.3
spindle and kinetochore associated complex subunit 1
chr5_+_115177178 0.24 ENST00000316788.7
adaptor-related protein complex 3, sigma 1 subunit
chr11_-_62439727 0.24 ENST00000528862.1
chromosome 11 open reading frame 48
chr14_+_24407940 0.24 ENST00000354854.1
DHRS4-AS1
chr5_+_138210919 0.24 ENST00000522013.1
ENST00000520260.1
ENST00000523298.1
ENST00000520865.1
ENST00000519634.1
ENST00000517533.1
ENST00000523685.1
ENST00000519768.1
ENST00000517656.1
ENST00000521683.1
ENST00000521640.1
ENST00000519116.1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr18_-_68004529 0.23 ENST00000578633.1
RP11-484N16.1
chr6_+_76599809 0.23 ENST00000430435.1
myosin VI
chr13_+_73302047 0.23 ENST00000377814.2
ENST00000377815.3
ENST00000390667.5
bora, aurora kinase A activator
chr6_+_30689350 0.23 ENST00000330914.3
tubulin, beta class I
chr1_+_84630053 0.23 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
protein kinase, cAMP-dependent, catalytic, beta
chr15_+_52121822 0.22 ENST00000558455.1
ENST00000308580.7
tropomodulin 3 (ubiquitous)
chr10_-_52645416 0.22 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
APOBEC1 complementation factor
chr1_-_68299130 0.22 ENST00000370982.3
guanine nucleotide binding protein (G protein), gamma 12
chr12_-_31744031 0.22 ENST00000389082.5
DENN/MADD domain containing 5B
chr5_-_76916396 0.22 ENST00000509971.1
WD repeat domain 41
chr9_-_21335240 0.22 ENST00000537938.1
kelch-like family member 9
chr8_+_19536083 0.22 ENST00000519803.1
RP11-1105O14.1
chr15_-_55700522 0.22 ENST00000564092.1
ENST00000310958.6
cell cycle progression 1
chr11_+_28129795 0.22 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
methyltransferase like 15
chr18_+_20513782 0.22 ENST00000399722.2
ENST00000399725.2
ENST00000399721.2
ENST00000583594.1
retinoblastoma binding protein 8
chr9_-_21335356 0.21 ENST00000359039.4
kelch-like family member 9
chr3_-_197025447 0.21 ENST00000346964.2
ENST00000357674.4
ENST00000314062.3
ENST00000448528.2
ENST00000419553.1
discs, large homolog 1 (Drosophila)
chr1_+_17559776 0.21 ENST00000537499.1
ENST00000413717.2
ENST00000536552.1
peptidyl arginine deiminase, type I
chr13_+_78109884 0.21 ENST00000377246.3
ENST00000349847.3
sciellin
chr8_+_107738240 0.21 ENST00000449762.2
ENST00000297447.6
oxidation resistance 1
chr19_+_18530184 0.21 ENST00000601357.2
single stranded DNA binding protein 4
chr12_-_39734783 0.21 ENST00000552961.1
kinesin family member 21A
chr5_+_140254884 0.21 ENST00000398631.2
protocadherin alpha 12
chr4_-_152149033 0.21 ENST00000514152.1
SH3 domain containing 19
chr4_-_85654615 0.21 ENST00000514711.1
WD repeat and FYVE domain containing 3
chr3_-_151160938 0.20 ENST00000489791.1
immunoglobulin superfamily, member 10
chr8_+_66619277 0.20 ENST00000521247.2
ENST00000527155.1
mitochondrial fission regulator 1
chr4_-_83765613 0.20 ENST00000503937.1
SEC31 homolog A (S. cerevisiae)
chr5_-_177659625 0.20 ENST00000323594.4
5-phosphohydroxy-L-lysine phospho-lyase
chr14_-_54955721 0.19 ENST00000554908.1
glia maturation factor, beta
chr12_-_90049828 0.19 ENST00000261173.2
ENST00000348959.3
ATPase, Ca++ transporting, plasma membrane 1
chr17_+_28705921 0.19 ENST00000225719.4
carboxypeptidase D
chr4_+_169418195 0.19 ENST00000261509.6
ENST00000335742.7
palladin, cytoskeletal associated protein
chr17_+_40996590 0.19 ENST00000253799.3
ENST00000452774.2
amine oxidase, copper containing 2 (retina-specific)
chr13_-_73301819 0.19 ENST00000377818.3
mitotic spindle organizing protein 1
chr7_-_55620433 0.18 ENST00000418904.1
vesicular, overexpressed in cancer, prosurvival protein 1
chr4_-_71532339 0.18 ENST00000254801.4
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr10_-_63995871 0.18 ENST00000315289.2
rhotekin 2
chr4_+_175205038 0.18 ENST00000457424.2
ENST00000514712.1
centrosomal protein 44kDa
chr5_-_111093759 0.18 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
neuronal regeneration related protein
chr6_-_47009996 0.18 ENST00000371243.2
G protein-coupled receptor 110
chrX_+_37639264 0.18 ENST00000378588.4
cytochrome b-245, beta polypeptide
chr12_+_94656297 0.18 ENST00000545312.1
plexin C1
chr16_-_1275257 0.18 ENST00000234798.4
tryptase gamma 1
chr5_-_96518907 0.18 ENST00000508447.1
ENST00000283109.3
RIO kinase 2
chr11_-_4629388 0.17 ENST00000526337.1
ENST00000300747.5
tripartite motif containing 68
chr2_-_37544209 0.17 ENST00000234179.2
protein kinase D3
chr17_+_35851570 0.17 ENST00000394386.1
dual specificity phosphatase 14
chr5_+_35856951 0.17 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
interleukin 7 receptor
chr11_+_112046190 0.17 ENST00000357685.5
ENST00000393032.2
ENST00000361053.4
beta-carotene oxygenase 2
chr12_-_28124903 0.17 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
parathyroid hormone-like hormone
chr1_+_196743943 0.16 ENST00000471440.2
ENST00000391985.3
complement factor H-related 3
chr17_-_39023462 0.16 ENST00000251643.4
keratin 12
chr5_-_150138061 0.16 ENST00000521533.1
ENST00000424236.1
dynactin 4 (p62)
chr1_+_81771806 0.16 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
latrophilin 2
chr16_+_53241854 0.16 ENST00000565803.1
chromodomain helicase DNA binding protein 9
chr14_+_77244349 0.16 ENST00000554743.1
vasohibin 1
chr7_+_79765071 0.16 ENST00000457358.2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr8_-_79717750 0.15 ENST00000263851.4
ENST00000379113.2
interleukin 7
chr9_-_86593238 0.15 ENST00000351839.3
heterogeneous nuclear ribonucleoprotein K
chr17_-_39165366 0.15 ENST00000391588.1
keratin associated protein 3-1
chr10_+_57358750 0.15 ENST00000512524.2
MT-RNR2-like 5
chr4_+_124571409 0.15 ENST00000514823.1
ENST00000511919.1
ENST00000508111.1
long intergenic non-protein coding RNA 1091
chr5_+_140165876 0.15 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
protocadherin alpha 1
chr10_-_43892668 0.15 ENST00000544000.1
heterogeneous nuclear ribonucleoprotein F
chr2_-_152589670 0.15 ENST00000604864.1
ENST00000603639.1
nebulin
chr8_-_101730061 0.15 ENST00000519100.1
poly(A) binding protein, cytoplasmic 1
chr4_-_100065440 0.15 ENST00000508393.1
ENST00000265512.7
alcohol dehydrogenase 4 (class II), pi polypeptide
chr14_+_53196872 0.14 ENST00000442123.2
ENST00000354586.4
serine/threonine/tyrosine interacting protein
chr14_+_24540154 0.14 ENST00000559778.1
ENST00000560761.1
ENST00000557889.1
copine VI (neuronal)
chr8_+_21823726 0.14 ENST00000433566.4
exportin 7
chr7_+_75024903 0.14 ENST00000323819.3
ENST00000430211.1
tripartite motif containing 73
chr1_-_160231451 0.14 ENST00000495887.1
DDB1 and CUL4 associated factor 8
chr14_+_102276132 0.14 ENST00000350249.3
ENST00000557621.1
ENST00000556946.1
protein phosphatase 2, regulatory subunit B', gamma
chr7_-_130353553 0.14 ENST00000330992.7
ENST00000445977.2
coatomer protein complex, subunit gamma 2
chr1_+_196743912 0.14 ENST00000367425.4
complement factor H-related 3
chr5_+_68530697 0.14 ENST00000256443.3
ENST00000514676.1
cyclin-dependent kinase 7
chr6_+_143999072 0.14 ENST00000440869.2
ENST00000367582.3
ENST00000451827.2
phosphatase and actin regulator 2
chr1_+_104159999 0.13 ENST00000414303.2
ENST00000423678.1
amylase, alpha 2A (pancreatic)
chr11_-_77122928 0.13 ENST00000528203.1
ENST00000528592.1
ENST00000528633.1
ENST00000529248.1
p21 protein (Cdc42/Rac)-activated kinase 1
chr18_-_57027194 0.13 ENST00000251047.5
lectin, mannose-binding, 1
chr12_-_57328187 0.13 ENST00000293502.1
short chain dehydrogenase/reductase family 9C, member 7
chr7_+_141490017 0.13 ENST00000247883.4
taste receptor, type 2, member 5
chr14_+_67831576 0.13 ENST00000555876.1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr2_+_172309634 0.13 ENST00000339506.3
DDB1 and CUL4 associated factor 17
chr4_+_156824840 0.13 ENST00000536354.2
tryptophan 2,3-dioxygenase

Network of associatons between targets according to the STRING database.

First level regulatory network of CDX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.3 1.4 GO:0090131 mesenchyme migration(GO:0090131)
0.2 0.9 GO:0006601 creatine biosynthetic process(GO:0006601)
0.2 0.5 GO:0060467 negative regulation of fertilization(GO:0060467) negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.2 0.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 1.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.4 GO:0046356 acetyl-CoA catabolic process(GO:0046356)
0.1 0.9 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.4 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.1 0.7 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.5 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.3 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.6 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.6 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.1 0.3 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.1 0.9 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.3 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 0.2 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.1 0.3 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.1 0.7 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.3 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.3 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.1 0.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.4 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.3 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.1 0.3 GO:0044855 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 0.5 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.1 0.2 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.2 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.1 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.2 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.8 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0001897 cytolysis by symbiont of host cells(GO:0001897)
0.0 0.7 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.2 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.3 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.1 GO:1904640 response to methionine(GO:1904640)
0.0 0.2 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.4 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.6 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.0 0.3 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.2 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.3 GO:0042262 DNA protection(GO:0042262)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.0 0.8 GO:0006825 copper ion transport(GO:0006825)
0.0 0.3 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.3 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.2 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.4 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 1.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.4 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.9 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.2 GO:0035973 aggrephagy(GO:0035973)
0.0 2.0 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.5 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293)
0.0 0.2 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.5 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.2 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.2 GO:0006069 ethanol oxidation(GO:0006069)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.9 GO:1990357 terminal web(GO:1990357)
0.1 1.9 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.2 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.1 0.5 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.2 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.1 0.5 GO:0000798 nuclear cohesin complex(GO:0000798)
0.1 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) astrocyte end-foot(GO:0097450)
0.0 0.1 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 0.9 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.1 GO:0070985 TFIIK complex(GO:0070985)
0.0 1.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.4 GO:0097227 sperm annulus(GO:0097227)
0.0 0.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.4 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.3 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0032010 phagolysosome(GO:0032010)
0.0 0.9 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0015068 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.2 0.5 GO:0015322 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.2 0.9 GO:0050436 microfibril binding(GO:0050436)
0.1 1.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.9 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.4 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 0.3 GO:0017130 poly(C) RNA binding(GO:0017130)
0.1 0.2 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.1 0.3 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.2 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.1 0.4 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 0.2 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.1 1.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.7 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.8 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.3 GO:0036033 mediator complex binding(GO:0036033)
0.1 0.7 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.2 GO:0019115 benzaldehyde dehydrogenase activity(GO:0019115)
0.1 0.3 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.1 0.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.2 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.3 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.2 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 1.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.3 GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.0 0.5 GO:0004568 chitinase activity(GO:0004568)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.4 GO:0050308 carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308)
0.0 0.3 GO:0045029 uridine nucleotide receptor activity(GO:0015065) UDP-activated nucleotide receptor activity(GO:0045029) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:1904854 proteasome core complex binding(GO:1904854)
0.0 0.1 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.7 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.0 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.3 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 1.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 1.5 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 1.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 2.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION Genes involved in Class I MHC mediated antigen processing & presentation
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling