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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for CREB5_CREM_JUNB

Z-value: 1.86

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Transcription factors associated with CREB5_CREM_JUNB

Gene Symbol Gene ID Gene Info
CREB5
ENSG00000146592.12 cAMP responsive element binding protein 5
CREM
ENSG00000095794.15 cAMP responsive element modulator
JUNB
ENSG00000171223.4 JunB proto-oncogene, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CREMhg19_v2_chr10_+_35416223_354164050.946.0e-02Click!
JUNBhg19_v2_chr19_+_12902289_12902310-0.772.3e-01Click!
CREB5hg19_v2_chr7_+_28448995_284490110.465.4e-01Click!

Activity profile of CREB5_CREM_JUNB motif

Sorted Z-values of CREB5_CREM_JUNB motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_37956409 2.49 ENST00000436072.2
SFRP4
secreted frizzled-related protein 4
chr1_+_203274639 1.94 ENST00000290551.4
BTG2
BTG family, member 2
chr8_-_95274536 1.89 ENST00000297596.2
ENST00000396194.2
GEM
GTP binding protein overexpressed in skeletal muscle
chr4_-_156298028 1.71 ENST00000433024.1
ENST00000379248.2
MAP9
microtubule-associated protein 9
chr11_-_28129656 1.66 ENST00000263181.6
KIF18A
kinesin family member 18A
chr1_+_85527987 1.65 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WDR63
WD repeat domain 63
chr9_-_99381660 1.60 ENST00000375240.3
ENST00000463569.1
CDC14B
cell division cycle 14B
chr1_-_245026388 1.54 ENST00000440865.1
HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr12_-_100660833 1.54 ENST00000551642.1
ENST00000416321.1
ENST00000550587.1
ENST00000549249.1
DEPDC4
DEP domain containing 4
chr5_+_112849373 1.53 ENST00000161863.4
ENST00000515883.1
YTHDC2
YTH domain containing 2
chr4_-_104119528 1.51 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
CENPE
centromere protein E, 312kDa
chr6_+_26204825 1.49 ENST00000360441.4
HIST1H4E
histone cluster 1, H4e
chr10_+_119000604 1.33 ENST00000298472.5
SLC18A2
solute carrier family 18 (vesicular monoamine transporter), member 2
chrX_-_135056106 1.32 ENST00000433339.2
MMGT1
membrane magnesium transporter 1
chr4_+_113558272 1.32 ENST00000509061.1
ENST00000508577.1
ENST00000513553.1
LARP7
La ribonucleoprotein domain family, member 7
chr19_+_45971246 1.30 ENST00000585836.1
ENST00000417353.2
ENST00000353609.3
ENST00000591858.1
ENST00000443841.2
ENST00000590335.1
FOSB
FBJ murine osteosarcoma viral oncogene homolog B
chr6_-_34855773 1.26 ENST00000420584.2
ENST00000361288.4
TAF11
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
chr14_-_80678512 1.24 ENST00000553968.1
DIO2
deiodinase, iodothyronine, type II
chr7_+_30174574 1.22 ENST00000409688.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr3_-_154042205 1.22 ENST00000329463.5
DHX36
DEAH (Asp-Glu-Ala-His) box polypeptide 36
chr6_-_26285737 1.21 ENST00000377727.1
ENST00000289352.1
HIST1H4H
histone cluster 1, H4h
chr1_+_110527308 1.20 ENST00000369799.5
AHCYL1
adenosylhomocysteinase-like 1
chr9_+_111696664 1.14 ENST00000374624.3
ENST00000445175.1
FAM206A
family with sequence similarity 206, member A
chr5_+_138210919 1.11 ENST00000522013.1
ENST00000520260.1
ENST00000523298.1
ENST00000520865.1
ENST00000519634.1
ENST00000517533.1
ENST00000523685.1
ENST00000519768.1
ENST00000517656.1
ENST00000521683.1
ENST00000521640.1
ENST00000519116.1
CTNNA1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr3_+_63898275 1.09 ENST00000538065.1
ATXN7
ataxin 7
chr9_-_99382065 1.08 ENST00000265659.2
ENST00000375241.1
ENST00000375236.1
CDC14B
cell division cycle 14B
chr22_+_32340447 1.06 ENST00000248975.5
YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr22_+_32340481 1.06 ENST00000397492.1
YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr4_-_140477928 1.05 ENST00000274031.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr10_+_14920843 1.03 ENST00000433779.1
ENST00000378325.3
ENST00000354919.6
ENST00000313519.5
ENST00000420416.1
SUV39H2
suppressor of variegation 3-9 homolog 2 (Drosophila)
chr19_+_16187085 1.03 ENST00000300933.4
TPM4
tropomyosin 4
chr7_-_124569991 1.01 ENST00000446993.1
ENST00000357628.3
ENST00000393329.1
POT1
protection of telomeres 1
chr6_-_86353510 0.98 ENST00000444272.1
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr1_+_168148169 0.94 ENST00000367833.2
TIPRL
TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr17_-_43209862 0.93 ENST00000322765.5
PLCD3
phospholipase C, delta 3
chr19_-_10341948 0.93 ENST00000590320.1
ENST00000592342.1
ENST00000588952.1
S1PR2
DNMT1
sphingosine-1-phosphate receptor 2
DNA (cytosine-5-)-methyltransferase 1
chr4_-_156298087 0.93 ENST00000311277.4
MAP9
microtubule-associated protein 9
chr3_+_42190714 0.92 ENST00000449246.1
TRAK1
trafficking protein, kinesin binding 1
chr1_+_28099700 0.91 ENST00000440806.2
STX12
syntaxin 12
chrX_+_155110956 0.91 ENST00000286448.6
ENST00000262640.6
ENST00000460621.1
VAMP7
vesicle-associated membrane protein 7
chr15_+_66797455 0.91 ENST00000446801.2
ZWILCH
zwilch kinetochore protein
chr5_+_139055055 0.90 ENST00000511457.1
CXXC5
CXXC finger protein 5
chr7_-_140624499 0.90 ENST00000288602.6
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr6_-_70506963 0.90 ENST00000370577.3
LMBRD1
LMBR1 domain containing 1
chr11_-_17555421 0.89 ENST00000526181.1
USH1C
Usher syndrome 1C (autosomal recessive, severe)
chr3_-_154042235 0.89 ENST00000308361.6
ENST00000496811.1
ENST00000544526.1
DHX36
DEAH (Asp-Glu-Ala-His) box polypeptide 36
chr4_-_146019287 0.86 ENST00000502847.1
ENST00000513054.1
ANAPC10
anaphase promoting complex subunit 10
chr1_-_242162375 0.85 ENST00000357246.3
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr5_+_56469843 0.85 ENST00000514387.2
GPBP1
GC-rich promoter binding protein 1
chr9_-_125027079 0.85 ENST00000417201.3
RBM18
RNA binding motif protein 18
chr6_-_47445214 0.85 ENST00000604014.1
RP11-385F7.1
RP11-385F7.1
chr3_+_99536663 0.84 ENST00000421999.2
ENST00000463526.1
CMSS1
cms1 ribosomal small subunit homolog (yeast)
chr7_+_30174426 0.83 ENST00000324453.8
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr4_-_113558014 0.82 ENST00000503172.1
ENST00000505019.1
ENST00000309071.5
C4orf21
chromosome 4 open reading frame 21
chr4_-_122744998 0.82 ENST00000274026.5
CCNA2
cyclin A2
chr7_-_6388537 0.81 ENST00000313324.4
ENST00000530143.1
FAM220A
family with sequence similarity 220, member A
chr1_+_28099683 0.81 ENST00000373943.4
STX12
syntaxin 12
chr4_-_156297949 0.80 ENST00000515654.1
MAP9
microtubule-associated protein 9
chr8_+_98788003 0.80 ENST00000521545.2
LAPTM4B
lysosomal protein transmembrane 4 beta
chr17_+_29421987 0.78 ENST00000431387.4
NF1
neurofibromin 1
chr8_+_26149274 0.78 ENST00000522535.1
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr4_+_85504075 0.78 ENST00000295887.5
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr2_+_37571845 0.77 ENST00000537448.1
QPCT
glutaminyl-peptide cyclotransferase
chrX_-_135056216 0.77 ENST00000305963.2
MMGT1
membrane magnesium transporter 1
chr11_+_4116005 0.76 ENST00000300738.5
RRM1
ribonucleotide reductase M1
chr12_+_112856690 0.76 ENST00000392597.1
ENST00000351677.2
PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr12_+_56477093 0.75 ENST00000549672.1
ENST00000415288.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr10_+_134351319 0.75 ENST00000368594.3
ENST00000368593.3
INPP5A
inositol polyphosphate-5-phosphatase, 40kDa
chr11_+_4116054 0.74 ENST00000423050.2
RRM1
ribonucleotide reductase M1
chr3_+_170075436 0.72 ENST00000476188.1
ENST00000259119.4
ENST00000426052.2
SKIL
SKI-like oncogene
chr8_-_102803163 0.72 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD
neurocalcin delta
chr15_+_66797627 0.71 ENST00000565627.1
ENST00000564179.1
ZWILCH
zwilch kinetochore protein
chr11_+_117070037 0.70 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
TAGLN
transgelin
chr11_+_18343800 0.70 ENST00000453096.2
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr6_-_121655593 0.68 ENST00000398212.2
TBC1D32
TBC1 domain family, member 32
chr5_+_139055021 0.67 ENST00000502716.1
ENST00000503511.1
CXXC5
CXXC finger protein 5
chr15_-_72612470 0.67 ENST00000287202.5
CELF6
CUGBP, Elav-like family member 6
chr7_+_38217920 0.67 ENST00000396013.1
ENST00000440144.1
ENST00000453225.1
ENST00000429075.1
STARD3NL
STARD3 N-terminal like
chr2_+_74781828 0.67 ENST00000340004.6
DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr20_+_5892037 0.67 ENST00000378961.4
CHGB
chromogranin B (secretogranin 1)
chr5_-_57756087 0.66 ENST00000274289.3
PLK2
polo-like kinase 2
chr2_+_220408724 0.66 ENST00000421791.1
ENST00000373883.3
ENST00000451952.1
TMEM198
transmembrane protein 198
chr8_-_101964231 0.66 ENST00000521309.1
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr12_+_54378923 0.65 ENST00000303460.4
HOXC10
homeobox C10
chr5_+_56469939 0.65 ENST00000506184.2
GPBP1
GC-rich promoter binding protein 1
chr6_+_28048753 0.64 ENST00000377325.1
ZNF165
zinc finger protein 165
chr17_-_49124230 0.64 ENST00000510283.1
ENST00000510855.1
SPAG9
sperm associated antigen 9
chr6_+_89791507 0.64 ENST00000354922.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr11_+_28129795 0.64 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
METTL15
methyltransferase like 15
chr1_-_221915418 0.64 ENST00000323825.3
ENST00000366899.3
DUSP10
dual specificity phosphatase 10
chr5_+_68513622 0.63 ENST00000512880.1
ENST00000602380.1
MRPS36
mitochondrial ribosomal protein S36
chr3_+_10068095 0.63 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
FANCD2
Fanconi anemia, complementation group D2
chr5_-_172198190 0.63 ENST00000239223.3
DUSP1
dual specificity phosphatase 1
chr11_-_77185094 0.63 ENST00000278568.4
ENST00000356341.3
PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
chr3_+_156544057 0.63 ENST00000498839.1
ENST00000470811.1
ENST00000356539.4
ENST00000483177.1
ENST00000477399.1
ENST00000491763.1
LEKR1
leucine, glutamate and lysine rich 1
chr11_+_18344106 0.63 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr17_-_7165662 0.62 ENST00000571881.2
ENST00000360325.7
CLDN7
claudin 7
chr12_+_69004805 0.61 ENST00000541216.1
RAP1B
RAP1B, member of RAS oncogene family
chr2_-_216300784 0.61 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1
fibronectin 1
chr12_+_100661156 0.61 ENST00000360820.2
SCYL2
SCY1-like 2 (S. cerevisiae)
chr4_-_76598544 0.61 ENST00000515457.1
ENST00000357854.3
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr1_+_109289279 0.60 ENST00000370008.3
STXBP3
syntaxin binding protein 3
chr5_-_32174369 0.60 ENST00000265070.6
GOLPH3
golgi phosphoprotein 3 (coat-protein)
chr14_+_60716159 0.60 ENST00000325658.3
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr1_+_173837488 0.60 ENST00000427304.1
ENST00000432989.1
ENST00000367702.1
ZBTB37
zinc finger and BTB domain containing 37
chr4_-_23891693 0.60 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr4_-_77997126 0.59 ENST00000537948.1
ENST00000507788.1
ENST00000237654.4
CCNI
cyclin I
chr6_-_30523865 0.59 ENST00000433809.1
GNL1
guanine nucleotide binding protein-like 1
chr15_-_32162833 0.59 ENST00000560598.1
OTUD7A
OTU domain containing 7A
chr14_+_68086515 0.59 ENST00000261783.3
ARG2
arginase 2
chr6_-_53213780 0.59 ENST00000304434.6
ENST00000370918.4
ELOVL5
ELOVL fatty acid elongase 5
chr12_+_124997766 0.59 ENST00000543970.1
RP11-83B20.1
RP11-83B20.1
chr11_-_119187826 0.58 ENST00000264036.4
MCAM
melanoma cell adhesion molecule
chr2_-_224467093 0.58 ENST00000305409.2
SCG2
secretogranin II
chr7_+_38217818 0.58 ENST00000009041.7
ENST00000544203.1
ENST00000434197.1
STARD3NL
STARD3 N-terminal like
chr22_-_41252962 0.58 ENST00000216218.3
ST13
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
chr4_+_128802016 0.57 ENST00000270861.5
ENST00000515069.1
ENST00000513090.1
ENST00000507249.1
PLK4
polo-like kinase 4
chr7_+_100464760 0.57 ENST00000200457.4
TRIP6
thyroid hormone receptor interactor 6
chr12_+_86268065 0.57 ENST00000551529.1
ENST00000256010.6
NTS
neurotensin
chr20_+_5892147 0.56 ENST00000455042.1
CHGB
chromogranin B (secretogranin 1)
chr11_+_66059339 0.56 ENST00000327259.4
TMEM151A
transmembrane protein 151A
chr6_-_53213587 0.56 ENST00000542638.1
ENST00000370913.5
ENST00000541407.1
ELOVL5
ELOVL fatty acid elongase 5
chr5_+_71403280 0.56 ENST00000511641.2
MAP1B
microtubule-associated protein 1B
chr1_+_166808692 0.55 ENST00000367876.4
POGK
pogo transposable element with KRAB domain
chr4_-_146019693 0.55 ENST00000514390.1
ANAPC10
anaphase promoting complex subunit 10
chr19_+_47616682 0.54 ENST00000594526.1
SAE1
SUMO1 activating enzyme subunit 1
chr6_+_139456226 0.54 ENST00000367658.2
HECA
headcase homolog (Drosophila)
chr2_+_27760247 0.54 ENST00000447166.1
AC109829.1
Uncharacterized protein
chr4_-_76598326 0.53 ENST00000503660.1
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr3_+_150126101 0.53 ENST00000361875.3
ENST00000361136.2
TSC22D2
TSC22 domain family, member 2
chr1_-_145382362 0.53 ENST00000419817.1
ENST00000421937.3
ENST00000433081.2
RP11-458D21.1
RP11-458D21.1
chr6_-_121655850 0.53 ENST00000422369.1
TBC1D32
TBC1 domain family, member 32
chr14_+_90864504 0.52 ENST00000544280.2
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr1_+_22379120 0.52 ENST00000400259.1
ENST00000344548.3
CDC42
cell division cycle 42
chr1_-_47184723 0.52 ENST00000371933.3
EFCAB14
EF-hand calcium binding domain 14
chr14_+_102276192 0.51 ENST00000557714.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr4_-_156297919 0.51 ENST00000450097.1
MAP9
microtubule-associated protein 9
chr4_-_57253587 0.51 ENST00000513376.1
ENST00000602986.1
ENST00000434343.2
ENST00000451613.1
ENST00000205214.6
ENST00000502617.1
AASDH
aminoadipate-semialdehyde dehydrogenase
chr1_+_212738676 0.51 ENST00000366981.4
ENST00000366987.2
ATF3
activating transcription factor 3
chr4_+_146019421 0.50 ENST00000502586.1
ABCE1
ATP-binding cassette, sub-family E (OABP), member 1
chr6_-_106773291 0.49 ENST00000343245.3
ATG5
autophagy related 5
chr17_+_27071002 0.49 ENST00000262395.5
ENST00000422344.1
ENST00000444415.3
ENST00000262396.6
TRAF4
TNF receptor-associated factor 4
chr5_+_162887556 0.49 ENST00000393915.4
ENST00000432118.2
ENST00000358715.3
HMMR
hyaluronan-mediated motility receptor (RHAMM)
chr1_+_166808667 0.49 ENST00000537173.1
ENST00000536514.1
ENST00000449930.1
POGK
pogo transposable element with KRAB domain
chr14_+_88851874 0.48 ENST00000393545.4
ENST00000356583.5
ENST00000555401.1
ENST00000553885.1
SPATA7
spermatogenesis associated 7
chr2_-_239198743 0.47 ENST00000440245.1
ENST00000431832.1
PER2
period circadian clock 2
chr22_+_31518938 0.47 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chr2_-_134326009 0.47 ENST00000409261.1
ENST00000409213.1
NCKAP5
NCK-associated protein 5
chr11_-_8832182 0.47 ENST00000527510.1
ENST00000528527.1
ENST00000528523.1
ENST00000313726.6
ST5
suppression of tumorigenicity 5
chr15_+_34394257 0.46 ENST00000397766.2
PGBD4
piggyBac transposable element derived 4
chr6_-_27440460 0.46 ENST00000377419.1
ZNF184
zinc finger protein 184
chr22_+_37959647 0.46 ENST00000415670.1
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr2_-_25194963 0.46 ENST00000264711.2
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr11_+_12695944 0.46 ENST00000361905.4
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr6_+_126661253 0.45 ENST00000368326.1
ENST00000368325.1
ENST00000368328.4
CENPW
centromere protein W
chr2_-_160473114 0.45 ENST00000392783.2
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr17_-_8059638 0.45 ENST00000584202.1
ENST00000354903.5
ENST00000577253.1
PER1
period circadian clock 1
chr12_+_69004705 0.45 ENST00000534899.1
ENST00000453560.2
ENST00000378985.3
ENST00000540209.1
ENST00000540781.1
ENST00000535492.1
ENST00000539091.1
ENST00000542145.1
ENST00000485252.2
ENST00000541386.1
ENST00000538877.1
ENST00000543697.1
RAP1B
RAP1B, member of RAS oncogene family
chr17_+_66508154 0.45 ENST00000358598.2
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr1_+_22379179 0.45 ENST00000315554.8
ENST00000421089.2
CDC42
cell division cycle 42
chr12_-_64616019 0.45 ENST00000311915.8
ENST00000398055.3
ENST00000544871.1
C12orf66
chromosome 12 open reading frame 66
chr11_-_119599794 0.45 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr14_+_38065052 0.45 ENST00000556845.1
TTC6
tetratricopeptide repeat domain 6
chr12_-_12715266 0.44 ENST00000228862.2
DUSP16
dual specificity phosphatase 16
chr1_+_17531614 0.44 ENST00000375471.4
PADI1
peptidyl arginine deiminase, type I
chr13_+_34392200 0.44 ENST00000434425.1
RFC3
replication factor C (activator 1) 3, 38kDa
chr16_-_3068171 0.44 ENST00000572154.1
ENST00000328796.4
CLDN6
claudin 6
chr13_+_111767650 0.44 ENST00000449979.1
ENST00000370623.3
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr15_+_96904487 0.43 ENST00000600790.1
AC087477.1
Uncharacterized protein
chr7_+_23221438 0.43 ENST00000258742.5
NUPL2
nucleoporin like 2
chr6_-_41888814 0.43 ENST00000409060.1
ENST00000265350.4
MED20
mediator complex subunit 20
chr1_-_150602035 0.43 ENST00000503241.1
ENST00000369016.4
ENST00000339643.5
ENST00000271690.8
ENST00000356527.5
ENST00000362052.7
ENST00000503345.1
ENST00000369014.5
ENST00000369009.3
ENSA
endosulfine alpha
chr16_-_90038866 0.43 ENST00000314994.3
CENPBD1
CENPB DNA-binding domains containing 1
chr5_-_95297678 0.43 ENST00000237853.4
ELL2
elongation factor, RNA polymerase II, 2
chr17_+_4643337 0.43 ENST00000592813.1
ZMYND15
zinc finger, MYND-type containing 15
chr17_+_53342311 0.43 ENST00000226067.5
HLF
hepatic leukemia factor
chr8_+_26149007 0.43 ENST00000380737.3
ENST00000524169.1
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr1_-_154164534 0.42 ENST00000271850.7
ENST00000368530.2
TPM3
tropomyosin 3
chr19_+_24009879 0.41 ENST00000354585.4
RPSAP58
ribosomal protein SA pseudogene 58
chr5_-_95297534 0.41 ENST00000513343.1
ENST00000431061.2
ELL2
elongation factor, RNA polymerase II, 2
chr5_+_56469775 0.41 ENST00000424459.3
GPBP1
GC-rich promoter binding protein 1
chr19_-_39402798 0.41 ENST00000571838.1
CTC-360G5.1
coiled-coil glutamate-rich protein 2
chr9_+_99212403 0.41 ENST00000375251.3
ENST00000375249.4
HABP4
hyaluronan binding protein 4
chr12_-_31882027 0.40 ENST00000541931.1
ENST00000535408.1
AMN1
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr9_-_33402506 0.40 ENST00000377425.4
ENST00000537089.1
ENST00000297988.1
ENST00000539936.1
ENST00000541274.1
AQP7
aquaporin 7
chr5_+_133562095 0.40 ENST00000602919.1
CTD-2410N18.3
CTD-2410N18.3
chr10_+_134210672 0.40 ENST00000305233.5
ENST00000368609.4
PWWP2B
PWWP domain containing 2B
chr4_+_48833312 0.40 ENST00000508293.1
ENST00000513391.2
OCIAD1
OCIA domain containing 1
chr4_-_170533723 0.40 ENST00000510533.1
ENST00000439128.2
ENST00000511633.1
ENST00000512193.1
ENST00000507142.1
NEK1
NIMA-related kinase 1
chr19_+_10362882 0.40 ENST00000393733.2
ENST00000588502.1
MRPL4
mitochondrial ribosomal protein L4
chr19_-_9546227 0.40 ENST00000361451.2
ENST00000361151.1
ZNF266
zinc finger protein 266
chr4_+_170541678 0.40 ENST00000360642.3
ENST00000512813.1
CLCN3
chloride channel, voltage-sensitive 3
chr1_+_173837214 0.40 ENST00000367704.1
ZBTB37
zinc finger and BTB domain containing 37
chr18_-_33647487 0.40 ENST00000590898.1
ENST00000357384.4
ENST00000319040.6
ENST00000588737.1
ENST00000399022.4
RPRD1A
regulation of nuclear pre-mRNA domain containing 1A
chr3_-_52312337 0.40 ENST00000469000.1
WDR82
WD repeat domain 82
chr16_-_10674528 0.40 ENST00000359543.3
EMP2
epithelial membrane protein 2
chr14_+_73525265 0.39 ENST00000525161.1
RBM25
RNA binding motif protein 25
chr2_+_37571717 0.39 ENST00000338415.3
ENST00000404976.1
QPCT
glutaminyl-peptide cyclotransferase
chr1_-_1293904 0.39 ENST00000309212.6
ENST00000342753.4
ENST00000445648.2
MXRA8
matrix-remodelling associated 8
chr3_+_44840679 0.39 ENST00000425755.1
KIF15
kinesin family member 15

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB5_CREM_JUNB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.4 1.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.4 1.3 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) sequestering of neurotransmitter(GO:0042137)
0.4 1.2 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.4 1.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.3 4.0 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.3 1.0 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.3 0.9 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.3 2.1 GO:1902741 interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.3 3.0 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.3 0.8 GO:0071373 cellular response to luteinizing hormone stimulus(GO:0071373)
0.2 1.7 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.2 0.7 GO:1904235 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.2 1.4 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.2 0.9 GO:1904106 protein localization to microvillus(GO:1904106)
0.2 1.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.2 0.6 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.2 1.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.2 0.6 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.2 0.8 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.2 0.6 GO:1904640 response to methionine(GO:1904640)
0.2 0.9 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.2 1.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.2 1.4 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.2 0.5 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2 0.6 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.2 1.5 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.2 1.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.6 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 2.7 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 1.1 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.8 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 2.1 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.5 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.1 1.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.5 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 0.7 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.9 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.1 0.7 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.1 0.6 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 1.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.4 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 0.6 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 2.6 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 0.3 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 0.5 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 1.7 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 1.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.0 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.1 0.3 GO:0021569 rhombomere 3 development(GO:0021569)
0.1 0.6 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 0.4 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.1 0.4 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 2.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.8 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 2.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.2 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.9 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.6 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.5 GO:0019249 lactate biosynthetic process(GO:0019249) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.1 0.8 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.2 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 1.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 1.3 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.3 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.1 0.6 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.6 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.3 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.4 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 1.2 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.3 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.3 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.2 GO:0006429 glutaminyl-tRNA aminoacylation(GO:0006425) leucyl-tRNA aminoacylation(GO:0006429)
0.1 0.7 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 1.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 1.0 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 0.9 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.1 0.4 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.7 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.6 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.1 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.2 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.1 0.4 GO:0015793 glycerol transport(GO:0015793)
0.1 0.4 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 0.2 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.1 0.4 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.2 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.1 0.3 GO:0043335 protein unfolding(GO:0043335)
0.1 0.6 GO:0000050 urea cycle(GO:0000050)
0.1 0.6 GO:0061042 vascular wound healing(GO:0061042)
0.1 0.4 GO:0060701 negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702)
0.1 0.6 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 0.3 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.1 0.2 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.7 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.4 GO:0070836 caveola assembly(GO:0070836)
0.0 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.6 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.8 GO:0031268 pseudopodium organization(GO:0031268)
0.0 1.5 GO:0006206 pyrimidine nucleobase metabolic process(GO:0006206)
0.0 0.4 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.3 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.1 GO:1903452 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.0 0.2 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.0 0.2 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of meiosis I(GO:0060903)
0.0 0.8 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 1.3 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.4 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.2 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.0 0.1 GO:0032826 natural killer cell differentiation involved in immune response(GO:0002325) regulation of natural killer cell differentiation involved in immune response(GO:0032826)
0.0 0.2 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.0 0.3 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.2 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.0 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.4 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.5 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.1 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.0 0.7 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.2 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 1.0 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 1.3 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293)
0.0 0.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 1.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.2 GO:0010868 negative regulation of triglyceride biosynthetic process(GO:0010868)
0.0 0.2 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0 0.2 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.0 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.9 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.4 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.8 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.5 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.2 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.7 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:0031081 nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
0.0 0.1 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.6 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.4 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.2 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.2 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.2 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.8 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.2 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.2 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.0 0.9 GO:0034453 microtubule anchoring(GO:0034453)
0.0 1.7 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.2 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.2 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.5 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.5 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.3 GO:0015871 choline transport(GO:0015871)
0.0 0.2 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.1 GO:0051905 melanosome localization(GO:0032400) establishment of melanosome localization(GO:0032401) melanosome transport(GO:0032402) pigment granule localization(GO:0051875) pigment granule transport(GO:0051904) establishment of pigment granule localization(GO:0051905)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.5 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0006116 NADH oxidation(GO:0006116)
0.0 0.1 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.4 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.8 GO:0032570 response to progesterone(GO:0032570)
0.0 0.1 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.2 GO:0043473 pigmentation(GO:0043473)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.5 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.2 GO:0090487 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.0 0.3 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.1 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.0 0.7 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 1.6 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.6 GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
0.0 1.0 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.6 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.3 GO:0045821 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.0 0.1 GO:0040031 snRNA pseudouridine synthesis(GO:0031120) snRNA modification(GO:0040031)
0.0 0.6 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.3 GO:0009617 response to bacterium(GO:0009617)
0.0 0.3 GO:0002504 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 0.2 GO:0090656 t-circle formation(GO:0090656)
0.0 0.1 GO:0008298 intracellular mRNA localization(GO:0008298)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:1990423 RZZ complex(GO:1990423)
0.3 0.8 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.2 7.4 GO:1990023 mitotic spindle midzone(GO:1990023)
0.2 0.7 GO:0075341 host cell PML body(GO:0075341)
0.2 3.0 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 1.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.2 0.7 GO:0005873 plus-end kinesin complex(GO:0005873)
0.2 0.5 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 1.3 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 1.3 GO:0000439 core TFIIH complex(GO:0000439)
0.1 2.9 GO:0051233 spindle midzone(GO:0051233)
0.1 0.5 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 1.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.9 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.7 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.6 GO:0098536 deuterosome(GO:0098536)
0.1 0.6 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.5 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 1.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.5 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 1.1 GO:0016600 flotillin complex(GO:0016600)
0.1 0.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 2.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.7 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.2 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 1.1 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.4 GO:0000322 storage vacuole(GO:0000322)
0.0 1.8 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.7 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 1.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 1.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.5 GO:0070187 telosome(GO:0070187)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 1.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 1.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 0.1 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 0.7 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 2.1 GO:0014704 intercalated disc(GO:0014704)
0.0 1.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 2.6 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.0 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.8 GO:0030686 90S preribosome(GO:0030686)
0.0 1.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 1.2 GO:0030286 dynein complex(GO:0030286)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.8 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.9 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.2 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 1.2 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.3 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0097440 apical dendrite(GO:0097440)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.3 0.9 GO:0015235 cobalamin transporter activity(GO:0015235)
0.2 1.0 GO:0032427 GBD domain binding(GO:0032427)
0.2 0.6 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.2 0.8 GO:0097677 STAT family protein binding(GO:0097677)
0.2 0.8 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) phosphatidate cytidylyltransferase activity(GO:0004605)
0.2 1.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 1.5 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.2 0.5 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.2 1.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.2 0.5 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.2 1.7 GO:0043515 kinetochore binding(GO:0043515)
0.2 0.5 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.2 1.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 0.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 2.1 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.1 1.0 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974) S-adenosyl-L-methionine binding(GO:1904047)
0.1 1.3 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.1 0.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 0.4 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 1.7 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.7 GO:0050436 microfibril binding(GO:0050436)
0.1 0.7 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 0.6 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 1.2 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.1 0.4 GO:0015254 glycerol channel activity(GO:0015254)
0.1 2.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.6 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 2.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.1 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.4 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 2.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.5 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.1 3.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.8 GO:0008432 JUN kinase binding(GO:0008432)
0.1 1.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.3 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.1 0.2 GO:0051908 double-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0051908)
0.1 0.5 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.2 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.1 0.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.3 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 1.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 1.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.8 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 0.2 GO:0004108 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.1 0.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 1.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 1.2 GO:0048156 tau protein binding(GO:0048156)
0.1 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.8 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.4 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 0.2 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.2 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.1 GO:0043337 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.2 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 3.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.5 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.2 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.6 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 1.5 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.5 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.4 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.2 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 1.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.9 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.4 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.1 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.3 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 1.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0003700 transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 1.6 GO:0030507 spectrin binding(GO:0030507)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.9 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.7 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 1.3 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.6 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 1.1 GO:0034062 RNA polymerase activity(GO:0034062)
0.0 0.1 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.4 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 1.2 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.2 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 0.2 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.7 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.3 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.2 GO:0005518 collagen binding(GO:0005518)
0.0 0.0 GO:0001031 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) 5S rDNA binding(GO:0080084)
0.0 3.7 GO:0008017 microtubule binding(GO:0008017)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 3.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 5.2 PID PLK1 PATHWAY PLK1 signaling events
0.1 4.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.8 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.6 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.9 PID ATR PATHWAY ATR signaling pathway
0.0 2.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 2.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.8 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.8 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.2 PID FOXO PATHWAY FoxO family signaling
0.0 0.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.2 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.3 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 1.6 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 1.1 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 3.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 0.6 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 2.4 REACTOME KINESINS Genes involved in Kinesins
0.0 1.0 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.6 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 1.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 2.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 1.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 1.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 1.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.8 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.1 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.9 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.8 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 1.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo