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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for DDIT3

Z-value: 1.29

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Transcription factors associated with DDIT3

Gene Symbol Gene ID Gene Info
DDIT3
ENSG00000175197.6 DNA damage inducible transcript 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DDIT3hg19_v2_chr12_-_57914275_579143040.841.6e-01Click!

Activity profile of DDIT3 motif

Sorted Z-values of DDIT3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_186330712 2.52 ENST00000411641.2
ENST00000273784.5
AHSG
alpha-2-HS-glycoprotein
chr3_-_148939598 1.86 ENST00000455472.3
CP
ceruloplasmin (ferroxidase)
chr1_+_150954493 1.74 ENST00000368947.4
ANXA9
annexin A9
chr6_-_86353510 1.28 ENST00000444272.1
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr11_-_8739383 1.01 ENST00000531060.1
ST5
suppression of tumorigenicity 5
chr11_+_47279155 0.92 ENST00000444396.1
ENST00000457932.1
ENST00000412937.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr10_-_92681033 0.79 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr12_-_12491608 0.74 ENST00000545735.1
MANSC1
MANSC domain containing 1
chr3_+_38017264 0.73 ENST00000436654.1
CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr3_-_148939835 0.70 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr11_+_34073195 0.69 ENST00000341394.4
CAPRIN1
cell cycle associated protein 1
chr18_-_55288973 0.68 ENST00000423481.2
ENST00000587194.1
ENST00000591599.1
ENST00000588661.1
NARS
asparaginyl-tRNA synthetase
chr4_+_157997273 0.66 ENST00000541722.1
ENST00000512619.1
GLRB
glycine receptor, beta
chr4_+_141178440 0.64 ENST00000394205.3
SCOC
short coiled-coil protein
chr10_-_116444371 0.59 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr9_+_70971815 0.55 ENST00000396392.1
ENST00000396396.1
PGM5
phosphoglucomutase 5
chr3_+_44840679 0.55 ENST00000425755.1
KIF15
kinesin family member 15
chr22_-_30901637 0.53 ENST00000381982.3
ENST00000255858.7
ENST00000540456.1
ENST00000392772.2
SEC14L4
SEC14-like 4 (S. cerevisiae)
chr6_+_80341000 0.53 ENST00000369838.4
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr19_-_6604094 0.53 ENST00000597430.2
CD70
CD70 molecule
chr14_-_92413353 0.52 ENST00000556154.1
FBLN5
fibulin 5
chr4_+_157997209 0.52 ENST00000264428.4
GLRB
glycine receptor, beta
chr7_-_56101826 0.48 ENST00000421626.1
PSPH
phosphoserine phosphatase
chr7_-_44530479 0.47 ENST00000355451.7
NUDCD3
NudC domain containing 3
chrX_-_100129128 0.47 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
NOX1
NADPH oxidase 1
chr11_-_8739566 0.47 ENST00000533020.1
ST5
suppression of tumorigenicity 5
chr14_-_92413727 0.46 ENST00000267620.10
FBLN5
fibulin 5
chr5_+_72143988 0.45 ENST00000506351.2
TNPO1
transportin 1
chr11_+_47279248 0.45 ENST00000449369.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr14_+_102276192 0.44 ENST00000557714.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr5_+_145583156 0.44 ENST00000265271.5
RBM27
RNA binding motif protein 27
chr9_+_80912059 0.43 ENST00000347159.2
ENST00000376588.3
PSAT1
phosphoserine aminotransferase 1
chr11_+_61976137 0.41 ENST00000244930.4
SCGB2A1
secretoglobin, family 2A, member 1
chr11_+_47279504 0.41 ENST00000441012.2
ENST00000437276.1
ENST00000436029.1
ENST00000467728.1
ENST00000405853.3
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr15_+_59730348 0.41 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
FAM81A
family with sequence similarity 81, member A
chr2_-_216300784 0.40 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1
fibronectin 1
chr17_-_34257731 0.40 ENST00000431884.2
ENST00000425909.3
ENST00000394528.3
ENST00000430160.2
RDM1
RAD52 motif 1
chr9_-_95055956 0.39 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
IARS
isoleucyl-tRNA synthetase
chr6_+_144606817 0.39 ENST00000433557.1
UTRN
utrophin
chr13_-_45915221 0.39 ENST00000309246.5
ENST00000379060.4
ENST00000379055.1
ENST00000527226.1
ENST00000379056.1
TPT1
tumor protein, translationally-controlled 1
chrX_+_9431324 0.38 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr19_-_35992780 0.36 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
DMKN
dermokine
chr11_-_8816375 0.35 ENST00000530580.1
ST5
suppression of tumorigenicity 5
chr16_+_56965960 0.34 ENST00000439977.2
ENST00000344114.4
ENST00000300302.5
ENST00000379792.2
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr20_+_5987890 0.34 ENST00000378868.4
CRLS1
cardiolipin synthase 1
chr10_-_13523073 0.34 ENST00000440282.1
BEND7
BEN domain containing 7
chr17_-_34257771 0.34 ENST00000394529.3
ENST00000293273.6
RDM1
RAD52 motif 1
chr2_-_43453734 0.33 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr1_+_90308981 0.33 ENST00000527156.1
LRRC8D
leucine rich repeat containing 8 family, member D
chr1_+_114447763 0.32 ENST00000369563.3
DCLRE1B
DNA cross-link repair 1B
chr3_+_130569429 0.31 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr1_+_111770294 0.31 ENST00000474304.2
CHI3L2
chitinase 3-like 2
chr2_+_63816295 0.29 ENST00000539945.1
ENST00000544381.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr10_-_17659234 0.28 ENST00000466335.1
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr10_-_17659357 0.27 ENST00000326961.6
ENST00000361271.3
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr4_+_6784401 0.25 ENST00000425103.1
ENST00000307659.5
KIAA0232
KIAA0232
chr9_-_95056010 0.25 ENST00000443024.2
IARS
isoleucyl-tRNA synthetase
chr2_-_63815860 0.24 ENST00000272321.7
ENST00000431065.1
WDPCP
WD repeat containing planar cell polarity effector
chr7_+_44040488 0.24 ENST00000258704.3
SPDYE1
speedy/RINGO cell cycle regulator family member E1
chr15_+_85923797 0.23 ENST00000559362.1
AKAP13
A kinase (PRKA) anchor protein 13
chr1_-_152196669 0.23 ENST00000368801.2
HRNR
hornerin
chr12_+_57857475 0.22 ENST00000528467.1
GLI1
GLI family zinc finger 1
chr2_-_63815628 0.22 ENST00000409562.3
WDPCP
WD repeat containing planar cell polarity effector
chr2_+_63816087 0.22 ENST00000409908.1
ENST00000442225.1
ENST00000409476.1
ENST00000436321.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr19_+_33865218 0.22 ENST00000585933.2
CEBPG
CCAAT/enhancer binding protein (C/EBP), gamma
chr5_+_145583107 0.21 ENST00000506502.1
RBM27
RNA binding motif protein 27
chr22_+_31518938 0.21 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chr2_-_208030295 0.21 ENST00000458272.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr8_+_26435915 0.20 ENST00000523027.1
DPYSL2
dihydropyrimidinase-like 2
chr19_+_1450112 0.19 ENST00000590469.1
ENST00000233607.2
ENST00000238483.4
ENST00000590877.1
APC2
adenomatosis polyposis coli 2
chr19_+_41497178 0.18 ENST00000324071.4
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr10_+_12391481 0.18 ENST00000378847.3
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr15_-_88799948 0.18 ENST00000394480.2
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr1_-_114447412 0.17 ENST00000369567.1
ENST00000369566.3
AP4B1
adaptor-related protein complex 4, beta 1 subunit
chr11_+_34073269 0.17 ENST00000389645.3
CAPRIN1
cell cycle associated protein 1
chr7_-_138363824 0.16 ENST00000419765.3
SVOPL
SVOP-like
chr13_+_24844979 0.16 ENST00000454083.1
SPATA13
spermatogenesis associated 13
chr3_+_15643476 0.16 ENST00000436193.1
ENST00000383778.4
BTD
biotinidase
chr2_-_208030886 0.15 ENST00000426163.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr19_+_12917364 0.15 ENST00000221486.4
RNASEH2A
ribonuclease H2, subunit A
chr11_-_8680383 0.15 ENST00000299550.6
TRIM66
tripartite motif containing 66
chr3_-_9595480 0.15 ENST00000287585.6
LHFPL4
lipoma HMGIC fusion partner-like 4
chr17_-_2117600 0.13 ENST00000572369.1
SMG6
SMG6 nonsense mediated mRNA decay factor
chr3_+_12392971 0.13 ENST00000287820.6
PPARG
peroxisome proliferator-activated receptor gamma
chr1_-_67519782 0.13 ENST00000235345.5
SLC35D1
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
chr17_+_30594823 0.13 ENST00000536287.1
RHBDL3
rhomboid, veinlet-like 3 (Drosophila)
chr2_-_101925055 0.12 ENST00000295317.3
RNF149
ring finger protein 149
chr8_-_11058847 0.12 ENST00000297303.4
ENST00000416569.2
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr12_-_63328817 0.11 ENST00000228705.6
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr16_-_70323422 0.11 ENST00000261772.8
AARS
alanyl-tRNA synthetase
chr5_-_137878887 0.11 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
ETF1
eukaryotic translation termination factor 1
chr12_-_122017542 0.11 ENST00000446152.2
KDM2B
lysine (K)-specific demethylase 2B
chr6_+_168399772 0.11 ENST00000443060.2
KIF25
kinesin family member 25
chr1_-_161277210 0.10 ENST00000491222.2
MPZ
myelin protein zero
chr15_+_85923856 0.10 ENST00000560302.1
ENST00000394518.2
ENST00000361243.2
ENST00000560256.1
AKAP13
A kinase (PRKA) anchor protein 13
chr8_+_24151553 0.10 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM28
ADAM metallopeptidase domain 28
chr10_+_86004802 0.10 ENST00000359452.4
ENST00000358110.5
ENST00000372092.3
RGR
retinal G protein coupled receptor
chr3_-_45883558 0.09 ENST00000445698.1
ENST00000296135.6
LZTFL1
leucine zipper transcription factor-like 1
chr4_-_119274121 0.09 ENST00000296498.3
PRSS12
protease, serine, 12 (neurotrypsin, motopsin)
chr1_-_114447683 0.08 ENST00000256658.4
ENST00000369564.1
AP4B1
adaptor-related protein complex 4, beta 1 subunit
chr8_+_27629459 0.08 ENST00000523566.1
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr5_+_118812237 0.08 ENST00000513628.1
HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4
chr12_+_32638897 0.08 ENST00000531134.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr10_+_60028818 0.07 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr17_-_47925379 0.07 ENST00000352793.2
ENST00000334568.4
ENST00000398154.1
ENST00000436235.1
ENST00000326219.5
TAC4
tachykinin 4 (hemokinin)
chr2_+_63816269 0.07 ENST00000432309.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr14_+_102276132 0.06 ENST00000350249.3
ENST00000557621.1
ENST00000556946.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr1_-_207143802 0.06 ENST00000324852.4
ENST00000400962.3
FCAMR
Fc receptor, IgA, IgM, high affinity
chr20_+_54987305 0.06 ENST00000371336.3
ENST00000434344.1
CASS4
Cas scaffolding protein family member 4
chr9_-_124991124 0.06 ENST00000394319.4
ENST00000340587.3
LHX6
LIM homeobox 6
chr16_+_56970567 0.05 ENST00000563911.1
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr14_-_23446021 0.05 ENST00000553592.1
AJUBA
ajuba LIM protein
chr4_+_111397216 0.05 ENST00000265162.5
ENPEP
glutamyl aminopeptidase (aminopeptidase A)
chr10_-_103874692 0.03 ENST00000361198.5
LDB1
LIM domain binding 1
chr5_+_118812294 0.03 ENST00000509514.1
HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4
chr2_-_161350305 0.02 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr8_-_82645082 0.01 ENST00000523361.1
ZFAND1
zinc finger, AN1-type domain 1
chr6_-_48036363 0.01 ENST00000543600.1
ENST00000398738.2
ENST00000339488.4
PTCHD4
patched domain containing 4
chr2_+_192141611 0.01 ENST00000392316.1
MYO1B
myosin IB
chr14_-_74226961 0.01 ENST00000286523.5
ENST00000435371.1
ELMSAN1
ELM2 and Myb/SANT-like domain containing 1
chr11_-_10315741 0.01 ENST00000256190.8
SBF2
SET binding factor 2
chr1_-_44820880 0.01 ENST00000372257.2
ENST00000457571.1
ENST00000452396.1
ERI3
ERI1 exoribonuclease family member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of DDIT3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.2 1.2 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.2 0.6 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.2 0.7 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 0.4 GO:1904235 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.1 0.5 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.1 1.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 2.5 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 0.5 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.1 1.0 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 2.6 GO:0006825 copper ion transport(GO:0006825)
0.1 0.4 GO:0042816 vitamin B6 metabolic process(GO:0042816)
0.1 0.2 GO:0060032 notochord regression(GO:0060032)
0.1 0.3 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.3 GO:0031627 telomeric loop formation(GO:0031627) telomeric 3' overhang formation(GO:0031860)
0.1 0.4 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.3 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.6 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.1 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.5 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.2 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.1 GO:2000230 regulation of cholesterol transporter activity(GO:0060694) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.5 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.5 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.8 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.4 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.3 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.4 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.2 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.9 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.1 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.4 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.2 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.2 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.2 1.3 GO:0097452 GAIT complex(GO:0097452)
0.1 0.5 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 1.0 GO:0071953 elastic fiber(GO:0071953)
0.1 0.2 GO:0036457 keratohyalin granule(GO:0036457)
0.1 0.4 GO:1990037 Lewy body core(GO:1990037)
0.1 0.4 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 5.0 GO:0072562 blood microparticle(GO:0072562)
0.0 0.9 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.5 GO:0044447 axoneme part(GO:0044447)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.3 0.8 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 0.6 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.2 2.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 1.8 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.5 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.1 0.3 GO:0043337 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.1 0.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.5 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.5 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 1.7 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.2 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 1.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 1.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.2 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.7 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.3 PID BMP PATHWAY BMP receptor signaling
0.0 1.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.9 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 1.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics