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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for DPRX

Z-value: 2.22

Motif logo

Transcription factors associated with DPRX

Gene Symbol Gene ID Gene Info
ENSG00000204595.1 divergent-paired related homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DPRXhg19_v2_chr19_+_54135310_541353100.909.9e-02Click!

Activity profile of DPRX motif

Sorted Z-values of DPRX motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_321340 17.14 ENST00000526811.1
interferon induced transmembrane protein 3
chr11_-_321050 8.40 ENST00000399808.4
interferon induced transmembrane protein 3
chr12_+_113344582 1.86 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr17_+_7482785 1.73 ENST00000250092.6
ENST00000380498.6
ENST00000584502.1
CD68 molecule
chr11_-_104916034 1.66 ENST00000528513.1
ENST00000375706.2
ENST00000375704.3
caspase recruitment domain family, member 16
chr12_+_113344755 1.63 ENST00000550883.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr11_-_104905840 1.54 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr12_+_113416265 1.28 ENST00000449768.2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr3_+_136676707 1.19 ENST00000329582.4
interleukin 20 receptor beta
chr12_+_113344811 1.17 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr6_-_32784687 1.14 ENST00000447394.1
ENST00000438763.2
major histocompatibility complex, class II, DO beta
chr4_+_89299885 1.14 ENST00000380265.5
ENST00000273960.3
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr3_+_136676851 1.11 ENST00000309741.5
interleukin 20 receptor beta
chr20_-_36794938 0.99 ENST00000453095.1
transglutaminase 2
chrX_-_77150911 0.99 ENST00000373336.3
magnesium transporter 1
chr1_-_153521714 0.87 ENST00000368713.3
S100 calcium binding protein A3
chr16_-_74734742 0.87 ENST00000308807.7
ENST00000573267.1
mixed lineage kinase domain-like
chr2_+_120517717 0.83 ENST00000420482.1
ENST00000488279.2
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr11_-_104972158 0.81 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr3_-_54962100 0.78 ENST00000273286.5
leucine-rich repeats and transmembrane domains 1
chrX_+_15767971 0.75 ENST00000479740.1
ENST00000454127.2
carbonic anhydrase VB, mitochondrial
chr1_+_66796401 0.72 ENST00000528771.1
phosphodiesterase 4B, cAMP-specific
chr20_-_36794902 0.70 ENST00000373403.3
transglutaminase 2
chr8_+_8559406 0.70 ENST00000519106.1
claudin 23
chr1_-_153521597 0.70 ENST00000368712.1
S100 calcium binding protein A3
chr1_+_162351503 0.69 ENST00000458626.2
chromosome 1 open reading frame 226
chr2_+_33701286 0.67 ENST00000403687.3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr16_+_30406423 0.65 ENST00000524644.1
zinc finger protein 48
chr17_-_47925379 0.64 ENST00000352793.2
ENST00000334568.4
ENST00000398154.1
ENST00000436235.1
ENST00000326219.5
tachykinin 4 (hemokinin)
chr5_+_118604385 0.61 ENST00000274456.6
tumor necrosis factor, alpha-induced protein 8
chr17_+_77021702 0.60 ENST00000392445.2
ENST00000354124.3
C1q and tumor necrosis factor related protein 1
chr5_-_77072145 0.56 ENST00000380377.4
tubulin folding cofactor A
chr6_-_170599561 0.56 ENST00000366756.3
delta-like 1 (Drosophila)
chr2_-_235405168 0.55 ENST00000339728.3
ADP-ribosylation factor-like 4C
chr11_+_60681346 0.52 ENST00000227525.3
transmembrane protein 109
chr7_+_66395596 0.52 ENST00000424964.2
ENST00000418375.1
transmembrane protein 248
chr19_-_12267524 0.52 ENST00000455799.1
ENST00000355738.1
ENST00000439556.2
ENST00000542938.1
zinc finger protein 625
chr1_+_16767195 0.51 ENST00000504551.2
ENST00000457722.2
ENST00000406746.1
ENST00000443980.2
NECAP endocytosis associated 2
chrX_-_15683147 0.51 ENST00000380342.3
transmembrane protein 27
chr6_-_30640761 0.51 ENST00000415603.1
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr19_-_59070239 0.50 ENST00000595957.1
ENST00000253023.3
ubiquitin-conjugating enzyme E2M
chr1_+_16767167 0.49 ENST00000337132.5
NECAP endocytosis associated 2
chr5_-_150460914 0.48 ENST00000389378.2
TNFAIP3 interacting protein 1
chr18_-_64271316 0.48 ENST00000540086.1
ENST00000580157.1
cadherin 19, type 2
chr17_+_48351785 0.47 ENST00000507382.1
transmembrane protein 92
chr19_+_56165480 0.46 ENST00000450554.2
U2 small nuclear RNA auxiliary factor 2
chr3_+_97483366 0.44 ENST00000463745.1
ENST00000462412.1
ADP-ribosylation factor-like 6
chr2_+_33661382 0.43 ENST00000402538.3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr1_+_169079823 0.42 ENST00000367813.3
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr15_+_63481668 0.41 ENST00000321437.4
ENST00000559006.1
ENST00000448330.2
RAB8B, member RAS oncogene family
chr12_+_130554803 0.40 ENST00000535487.1
RP11-474D1.2
chr19_+_41284121 0.40 ENST00000594800.1
ENST00000357052.2
ENST00000602173.1
RAB4B, member RAS oncogene family
chr11_-_61734599 0.39 ENST00000532601.1
ferritin, heavy polypeptide 1
chrX_+_115567767 0.39 ENST00000371900.4
solute carrier family 6 (amino acid transporter), member 14
chrX_-_140336629 0.39 ENST00000358993.2
SPANX family, member C
chr8_+_145215928 0.37 ENST00000528919.1
maestro heat-like repeat family member 1
chr2_+_27799389 0.37 ENST00000408964.2
chromosome 2 open reading frame 16
chr18_-_32957260 0.37 ENST00000587422.1
ENST00000306346.1
ENST00000589332.1
ENST00000586687.1
ENST00000585522.1
zinc finger protein 396
chrX_+_69488174 0.37 ENST00000480877.2
ENST00000307959.8
arrestin 3, retinal (X-arrestin)
chr5_+_150040403 0.36 ENST00000517768.1
ENST00000297130.4
myozenin 3
chr17_+_41150290 0.36 ENST00000589037.1
ENST00000253788.5
ribosomal protein L27
chr3_+_63953415 0.36 ENST00000484332.1
ataxin 7
chr3_+_49058444 0.35 ENST00000326925.6
ENST00000395458.2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr18_-_52989525 0.35 ENST00000457482.3
transcription factor 4
chr1_-_36615065 0.35 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
trafficking protein particle complex 3
chr17_-_37557846 0.34 ENST00000394294.3
ENST00000583610.1
ENST00000264658.6
F-box and leucine-rich repeat protein 20
chr16_+_81272287 0.34 ENST00000425577.2
ENST00000564552.1
beta-carotene 15,15'-monooxygenase 1
chr19_+_8455077 0.34 ENST00000328024.6
RAB11B, member RAS oncogene family
chr5_-_180235755 0.33 ENST00000502678.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr1_+_15986364 0.33 ENST00000345034.1
regulatory solute carrier protein, family 1, member 1
chr7_-_75401513 0.33 ENST00000005180.4
chemokine (C-C motif) ligand 26
chr20_-_34330129 0.33 ENST00000397370.3
ENST00000528062.3
ENST00000407261.4
ENST00000374038.3
ENST00000361162.6
RNA binding motif protein 39
chr1_+_183441500 0.33 ENST00000456731.2
SMG7 nonsense mediated mRNA decay factor
chr1_+_207262881 0.33 ENST00000451804.2
complement component 4 binding protein, beta
chr20_+_22034809 0.32 ENST00000449427.1
RP11-125P18.1
chr7_+_137761220 0.32 ENST00000242375.3
ENST00000438242.1
aldo-keto reductase family 1, member D1
chr14_-_69446034 0.32 ENST00000193403.6
actinin, alpha 1
chr5_+_169010638 0.31 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
spindle apparatus coiled-coil protein 1
chr6_+_31555045 0.31 ENST00000396101.3
ENST00000490742.1
leukocyte specific transcript 1
chr15_+_42565844 0.31 ENST00000566442.1
glucosidase, alpha; neutral C
chr14_-_101034811 0.31 ENST00000553553.1
brain-enriched guanylate kinase-associated
chr9_-_23821273 0.30 ENST00000380110.4
ELAV like neuron-specific RNA binding protein 2
chr2_+_7118755 0.30 ENST00000433456.1
ring finger protein 144A
chr5_+_140345820 0.30 ENST00000289269.5
protocadherin alpha subfamily C, 2
chr7_-_122342988 0.30 ENST00000434824.1
ring finger protein 148
chr11_+_65343494 0.29 ENST00000309295.4
ENST00000533237.1
EH domain binding protein 1-like 1
chr9_-_112083229 0.29 ENST00000374566.3
ENST00000374557.4
erythrocyte membrane protein band 4.1 like 4B
chr16_-_4664860 0.29 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
ENST00000591401.1
ENST00000283474.7
UBA-like domain containing 1
chr17_+_43318434 0.29 ENST00000587489.1
formin-like 1
chr16_+_57844549 0.29 ENST00000564282.1
uncharacterized protein LOC388282
chr6_-_35480705 0.29 ENST00000229771.6
tubby like protein 1
chr19_-_50529193 0.29 ENST00000596445.1
ENST00000599538.1
vaccinia related kinase 3
chr16_-_4665023 0.28 ENST00000591897.1
UBA-like domain containing 1
chr1_-_209741018 0.28 ENST00000424696.2
RP1-272L16.1
chr17_+_6916527 0.27 ENST00000552321.1
ribonuclease, RNase K
chr6_-_33290580 0.27 ENST00000446511.1
ENST00000446403.1
ENST00000414083.2
ENST00000266000.6
ENST00000374542.5
death-domain associated protein
chr19_+_7981030 0.27 ENST00000565886.1
transforming growth factor, beta receptor III-like
chr7_+_137761199 0.27 ENST00000411726.2
aldo-keto reductase family 1, member D1
chr20_-_45985414 0.27 ENST00000461685.1
ENST00000372023.3
ENST00000540497.1
ENST00000435836.1
ENST00000471951.2
ENST00000352431.2
ENST00000396281.4
ENST00000355972.4
ENST00000360911.3
zinc finger, MYND-type containing 8
chr5_-_54988559 0.27 ENST00000502247.1
solute carrier family 38, member 9
chr1_+_150039877 0.27 ENST00000419023.1
vacuolar protein sorting 45 homolog (S. cerevisiae)
chr8_+_94752349 0.27 ENST00000391680.1
RBM12B antisense RNA 1
chr19_+_55738587 0.26 ENST00000598855.1
Uncharacterized protein; cDNA FLJ45856 fis, clone OCBBF2025631
chr1_+_164600184 0.26 ENST00000482110.1
pre-B-cell leukemia homeobox 1
chrX_+_53449839 0.26 ENST00000457095.1
RIB43A domain with coiled-coils 1
chr3_+_93781728 0.26 ENST00000314622.4
NOP2/Sun domain family, member 3
chr14_+_92789498 0.26 ENST00000531433.1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr6_+_26383318 0.25 ENST00000469230.1
ENST00000490025.1
ENST00000356709.4
ENST00000352867.2
ENST00000493275.1
ENST00000472507.1
ENST00000482536.1
ENST00000432533.2
ENST00000482842.1
butyrophilin, subfamily 2, member A2
chr17_-_15244894 0.25 ENST00000338696.2
ENST00000543896.1
ENST00000539245.1
ENST00000539316.1
ENST00000395930.1
tektin 3
chr1_+_36772691 0.25 ENST00000312808.4
ENST00000505871.1
SH3 domain containing 21
chr2_-_26700900 0.25 ENST00000338581.6
ENST00000339598.3
ENST00000402415.3
otoferlin
chr8_+_54764346 0.25 ENST00000297313.3
ENST00000344277.6
regulator of G-protein signaling 20
chr16_-_21416640 0.24 ENST00000542817.1
nuclear pore complex interacting protein family, member B3
chr6_-_37225391 0.24 ENST00000356757.2
transmembrane protein 217
chr12_-_124419531 0.24 ENST00000514254.2
dynein, axonemal, heavy chain 10 opposite strand
chr3_+_111630451 0.23 ENST00000495180.1
pleckstrin homology-like domain, family B, member 2
chr20_+_1875942 0.23 ENST00000358771.4
signal-regulatory protein alpha
chr20_-_45985464 0.23 ENST00000458360.2
ENST00000262975.4
zinc finger, MYND-type containing 8
chr17_+_12626199 0.23 ENST00000609971.1
AC005358.1
chr12_-_53171128 0.22 ENST00000332411.2
keratin 76
chr17_+_7531281 0.22 ENST00000575729.1
ENST00000340624.5
sex hormone-binding globulin
chr8_+_110656344 0.22 ENST00000499579.1
Uncharacterized protein
chr12_+_54718904 0.22 ENST00000262061.2
ENST00000549043.1
ENST00000552218.1
ENST00000553231.1
ENST00000552362.1
ENST00000455864.2
ENST00000416254.2
ENST00000549116.1
ENST00000551779.1
coatomer protein complex, subunit zeta 1
chr3_-_178976996 0.22 ENST00000485523.1
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr5_-_77072085 0.22 ENST00000518338.2
ENST00000520039.1
ENST00000306388.6
ENST00000520361.1
tubulin folding cofactor A
chr4_-_87374330 0.22 ENST00000511328.1
ENST00000503911.1
mitogen-activated protein kinase 10
chr11_+_111385497 0.22 ENST00000375618.4
ENST00000529167.1
ENST00000332814.6
chromosome 11 open reading frame 88
chr6_+_31554826 0.22 ENST00000376089.2
ENST00000396112.2
leukocyte specific transcript 1
chr3_-_45883558 0.22 ENST00000445698.1
ENST00000296135.6
leucine zipper transcription factor-like 1
chr19_-_4831701 0.22 ENST00000248244.5
toll-like receptor adaptor molecule 1
chr8_+_72755367 0.22 ENST00000537896.1
Protein LOC100132891; cDNA FLJ53548
chr11_+_61560348 0.21 ENST00000535723.1
ENST00000574708.1
flap structure-specific endonuclease 1
fatty acid desaturase 2
chr19_+_36139125 0.21 ENST00000246554.3
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
chr4_+_159131630 0.21 ENST00000504569.1
ENST00000509278.1
ENST00000514558.1
ENST00000503200.1
transmembrane protein 144
chr9_+_37667978 0.20 ENST00000539465.1
FERM and PDZ domain containing 1
chr17_+_37030127 0.20 ENST00000419929.1
LIM and SH3 protein 1
chr6_-_30640811 0.20 ENST00000376442.3
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr6_-_37225367 0.20 ENST00000336655.2
transmembrane protein 217
chr16_-_21849091 0.19 ENST00000537951.1
nuclear pore complex interacting protein family, member B4
chr2_+_3622795 0.19 ENST00000304921.5
ribosomal protein S7
chr14_-_22005343 0.19 ENST00000327430.3
spalt-like transcription factor 2
chr9_-_5830768 0.19 ENST00000381506.3
endoplasmic reticulum metallopeptidase 1
chr8_+_86999516 0.19 ENST00000521564.1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr6_+_46761118 0.18 ENST00000230588.4
meprin A, alpha (PABA peptide hydrolase)
chr9_+_116343192 0.18 ENST00000471324.2
regulator of G-protein signaling 3
chr7_+_134576317 0.18 ENST00000424922.1
ENST00000495522.1
caldesmon 1
chr20_+_10199566 0.18 ENST00000430336.1
synaptosomal-associated protein, 25kDa
chr12_+_133066137 0.18 ENST00000434748.2
fibrosin-like 1
chr1_-_152086556 0.17 ENST00000368804.1
trichohyalin
chr15_-_93965805 0.17 ENST00000556708.1
RP11-164C12.2
chr3_+_188664988 0.17 ENST00000433971.1
tumor protein p63 regulated 1
chr20_-_45985172 0.17 ENST00000536340.1
zinc finger, MYND-type containing 8
chr14_-_22005197 0.17 ENST00000541965.1
spalt-like transcription factor 2
chr19_+_36157715 0.17 ENST00000379013.2
ENST00000222275.2
uroplakin 1A
chr1_+_150039787 0.17 ENST00000535106.1
vacuolar protein sorting 45 homolog (S. cerevisiae)
chr15_+_34261089 0.17 ENST00000383263.5
cholinergic receptor, muscarinic 5
chr4_-_153700864 0.16 ENST00000304337.2
tigger transposable element derived 4
chrX_+_139791917 0.16 ENST00000607004.1
ENST00000370535.3
long intergenic non-protein coding RNA 632
chr7_+_20686946 0.16 ENST00000443026.2
ENST00000406935.1
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr15_+_81475047 0.16 ENST00000559388.1
interleukin 16
chr7_-_15726296 0.16 ENST00000262041.5
mesenchyme homeobox 2
chr1_-_45988542 0.16 ENST00000424390.1
peroxiredoxin 1
chr18_-_70532906 0.16 ENST00000299430.2
ENST00000397929.1
neuropilin (NRP) and tolloid (TLL)-like 1
chr6_+_26383404 0.16 ENST00000416795.2
ENST00000494184.1
butyrophilin, subfamily 2, member A2
chr20_+_361890 0.16 ENST00000449710.1
ENST00000422053.2
tribbles pseudokinase 3
chr2_-_158184211 0.16 ENST00000397283.2
ermin, ERM-like protein
chr1_+_74701062 0.15 ENST00000326637.3
TNNI3 interacting kinase
chr17_+_73663402 0.15 ENST00000355423.3
SAP30 binding protein
chr2_+_113342011 0.15 ENST00000324913.5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr1_+_207262170 0.15 ENST00000367078.3
complement component 4 binding protein, beta
chr10_-_105845674 0.15 ENST00000353479.5
ENST00000369733.3
collagen, type XVII, alpha 1
chr11_-_61560053 0.15 ENST00000537328.1
transmembrane protein 258
chr5_+_138677515 0.15 ENST00000265192.4
ENST00000511706.1
poly(A) binding protein interacting protein 2
chr2_-_30144432 0.14 ENST00000389048.3
anaplastic lymphoma receptor tyrosine kinase
chr19_-_22806764 0.14 ENST00000598042.1
AC011516.2
chr6_+_55192267 0.14 ENST00000340465.2
GDNF family receptor alpha like
chr7_-_97881429 0.14 ENST00000420697.1
ENST00000379795.3
ENST00000415086.1
ENST00000542604.1
ENST00000447648.2
tectonin beta-propeller repeat containing 1
chr2_+_113342163 0.14 ENST00000409719.1
coiled-coil-helix-coiled-coil-helix domain containing 5
chrX_+_53449805 0.14 ENST00000414955.2
RIB43A domain with coiled-coils 1
chr1_-_11751529 0.14 ENST00000376672.1
MAD2 mitotic arrest deficient-like 2 (yeast)
chr20_+_33759854 0.14 ENST00000216968.4
protein C receptor, endothelial
chr2_+_234216454 0.13 ENST00000447536.1
ENST00000409110.1
S-antigen; retina and pineal gland (arrestin)
chr8_+_145597713 0.13 ENST00000308860.6
ENST00000532190.1
aarF domain containing kinase 5
chr13_+_28712614 0.13 ENST00000380958.3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr19_-_50370799 0.13 ENST00000600910.1
ENST00000322344.3
ENST00000600573.1
polynucleotide kinase 3'-phosphatase
chr19_-_14628645 0.13 ENST00000598235.1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr1_-_150780757 0.13 ENST00000271651.3
cathepsin K
chr8_-_124037890 0.13 ENST00000519018.1
ENST00000523036.1
derlin 1
chr10_-_116418053 0.13 ENST00000277895.5
actin binding LIM protein 1
chr1_-_45805667 0.13 ENST00000488731.2
ENST00000435155.1
mutY homolog
chr3_-_15469045 0.13 ENST00000450816.2
methyltransferase like 6
chr7_+_28452130 0.13 ENST00000357727.2
cAMP responsive element binding protein 5
chr6_+_36164487 0.13 ENST00000357641.6
bromodomain and PHD finger containing, 3
chr8_+_1772132 0.12 ENST00000349830.3
ENST00000520359.1
ENST00000518288.1
ENST00000398560.1
Rho guanine nucleotide exchange factor (GEF) 10
chr1_+_183441600 0.12 ENST00000367537.3
SMG7 nonsense mediated mRNA decay factor
chr10_+_118187379 0.12 ENST00000369230.3
pancreatic lipase-related protein 3
chrX_+_15525426 0.12 ENST00000342014.6
BMX non-receptor tyrosine kinase
chr1_+_207262540 0.12 ENST00000452902.2
complement component 4 binding protein, beta
chr1_+_207262627 0.12 ENST00000391923.1
complement component 4 binding protein, beta
chr5_+_138678131 0.12 ENST00000394795.2
ENST00000510080.1
poly(A) binding protein interacting protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of DPRX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 25.5 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.6 2.3 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.6 2.3 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.4 1.7 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.4 1.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.2 1.7 GO:0071494 cellular response to UV-C(GO:0071494)
0.2 0.6 GO:0048633 negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of mechanoreceptor differentiation(GO:0045632) positive regulation of skeletal muscle tissue growth(GO:0048633) negative regulation of inner ear receptor cell differentiation(GO:2000981)
0.1 0.6 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.1 0.6 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 1.3 GO:0018377 protein myristoylation(GO:0018377)
0.1 0.4 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.5 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.3 GO:0072738 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.1 0.8 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.1 0.3 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.1 0.7 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.1 0.6 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.5 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.1 0.2 GO:1903565 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.8 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 1.1 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.8 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.2 GO:0001757 somite specification(GO:0001757)
0.1 0.4 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.0 0.4 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 4.7 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.2 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.0 0.4 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.3 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.4 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.3 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.2 GO:0048749 compound eye development(GO:0048749)
0.0 0.5 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.1 GO:2001033 regulation of DNA ligase activity(GO:1904875) negative regulation of double-strand break repair via nonhomologous end joining(GO:2001033)
0.0 0.3 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.3 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.3 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.1 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.1 GO:0098502 DNA dephosphorylation(GO:0098502)
0.0 0.1 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 1.0 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.5 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.2 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.1 GO:0098704 fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)
0.0 0.0 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.3 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.2 GO:1903689 regulation of wound healing, spreading of epidermal cells(GO:1903689) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.3 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.5 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.1 GO:1904868 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.5 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.3 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.0 GO:0097179 protease inhibitor complex(GO:0097179)
0.1 1.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 23.9 GO:0031902 late endosome membrane(GO:0031902)
0.1 0.4 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.1 0.4 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.5 GO:0089701 U2AF(GO:0089701)
0.1 1.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.1 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.4 GO:0051286 cell tip(GO:0051286)
0.0 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 1.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 1.0 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.7 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:0032059 bleb(GO:0032059)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.8 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:0098791 organelle subcompartment(GO:0031984) Golgi subcompartment(GO:0098791)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.0 GO:0032437 cuticular plate(GO:0032437)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.4 2.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 2.5 GO:0089720 caspase binding(GO:0089720)
0.1 1.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.4 GO:0051373 FATZ binding(GO:0051373)
0.1 0.6 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.1 1.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.5 GO:0002046 opsin binding(GO:0002046)
0.1 0.3 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.5 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 1.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.5 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1 0.3 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 0.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.5 GO:0070739 NEDD8 transferase activity(GO:0019788) protein-glutamic acid ligase activity(GO:0070739)
0.0 0.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.4 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558) maltose alpha-glucosidase activity(GO:0032450)
0.0 0.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.2 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) linoleoyl-CoA desaturase activity(GO:0016213) 5'-flap endonuclease activity(GO:0017108)
0.0 1.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.4 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.4 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0086040 sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086040)
0.0 0.6 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.3 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0005497 androgen binding(GO:0005497)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0016297 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.0 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.5 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.5 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.0 GO:0004769 steroid delta-isomerase activity(GO:0004769)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 31.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 2.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.6 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events