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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for DRGX_PROP1

Z-value: 1.26

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Transcription factors associated with DRGX_PROP1

Gene Symbol Gene ID Gene Info
DRGX
ENSG00000165606.4 dorsal root ganglia homeobox
PROP1
ENSG00000175325.2 PROP paired-like homeobox 1

Activity profile of DRGX_PROP1 motif

Sorted Z-values of DRGX_PROP1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_155484103 3.10 ENST00000302068.4
FGB
fibrinogen beta chain
chr4_+_155484155 2.89 ENST00000509493.1
FGB
fibrinogen beta chain
chr3_-_195310802 2.34 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr8_-_95229531 1.91 ENST00000450165.2
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr6_+_26087646 1.56 ENST00000309234.6
HFE
hemochromatosis
chr10_+_115312766 1.47 ENST00000351270.3
HABP2
hyaluronan binding protein 2
chr6_-_32908792 1.39 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr6_-_107235331 1.32 ENST00000433965.1
ENST00000430094.1
RP1-60O19.1
RP1-60O19.1
chr1_-_200379180 1.32 ENST00000294740.3
ZNF281
zinc finger protein 281
chr1_-_151148492 1.31 ENST00000295314.4
TMOD4
tropomodulin 4 (muscle)
chr7_-_111032971 1.17 ENST00000450877.1
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr3_-_27764190 1.05 ENST00000537516.1
EOMES
eomesodermin
chr3_+_149192475 0.99 ENST00000465758.1
TM4SF4
transmembrane 4 L six family member 4
chr6_-_32908765 0.97 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr3_-_87325612 0.96 ENST00000561167.1
ENST00000560656.1
ENST00000344265.3
POU1F1
POU class 1 homeobox 1
chr6_-_107235378 0.94 ENST00000606430.1
RP1-60O19.1
RP1-60O19.1
chr5_-_87516448 0.93 ENST00000511218.1
TMEM161B
transmembrane protein 161B
chr6_-_107235287 0.92 ENST00000436659.1
ENST00000428750.1
ENST00000427903.1
RP1-60O19.1
RP1-60O19.1
chr18_+_20714525 0.91 ENST00000400473.2
CABLES1
Cdk5 and Abl enzyme substrate 1
chr3_+_149191723 0.88 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr8_-_17752912 0.80 ENST00000398054.1
ENST00000381840.2
FGL1
fibrinogen-like 1
chrX_+_77166172 0.78 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr4_-_76649546 0.76 ENST00000508510.1
ENST00000509561.1
ENST00000499709.2
ENST00000511868.1
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr8_-_17752996 0.76 ENST00000381841.2
ENST00000427924.1
FGL1
fibrinogen-like 1
chr12_+_14572070 0.75 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
ATF7IP
activating transcription factor 7 interacting protein
chr1_-_241799232 0.75 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chr2_-_114461655 0.74 ENST00000424612.1
AC017074.2
AC017074.2
chr1_-_151148442 0.66 ENST00000441701.1
ENST00000416280.2
TMOD4
tropomodulin 4 (muscle)
chr8_+_26150628 0.58 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr4_+_113568207 0.58 ENST00000511529.1
LARP7
La ribonucleoprotein domain family, member 7
chr2_+_44502597 0.57 ENST00000260649.6
ENST00000409387.1
SLC3A1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr11_-_96076334 0.57 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr17_+_71228740 0.56 ENST00000268942.8
ENST00000359042.2
C17orf80
chromosome 17 open reading frame 80
chr4_+_48485341 0.56 ENST00000273861.4
SLC10A4
solute carrier family 10, member 4
chr14_-_83262540 0.56 ENST00000554451.1
RP11-11K13.1
RP11-11K13.1
chr9_+_42671887 0.55 ENST00000456520.1
ENST00000377391.3
CBWD7
COBW domain containing 7
chr14_-_38064198 0.54 ENST00000250448.2
FOXA1
forkhead box A1
chr4_+_142558078 0.54 ENST00000529613.1
IL15
interleukin 15
chr1_-_234667504 0.53 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
RP5-855F14.1
chr5_-_134735568 0.52 ENST00000510038.1
ENST00000304332.4
H2AFY
H2A histone family, member Y
chr14_+_38065052 0.51 ENST00000556845.1
TTC6
tetratricopeptide repeat domain 6
chr22_+_25615489 0.51 ENST00000398215.2
CRYBB2
crystallin, beta B2
chr2_-_55496174 0.50 ENST00000417363.1
ENST00000412530.1
ENST00000394600.3
ENST00000366137.2
ENST00000420637.1
MTIF2
mitochondrial translational initiation factor 2
chr15_+_57511609 0.49 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
TCF12
transcription factor 12
chr2_+_191334212 0.49 ENST00000444317.1
ENST00000535751.1
MFSD6
major facilitator superfamily domain containing 6
chr1_+_50459990 0.47 ENST00000448346.1
AL645730.2
AL645730.2
chr16_+_53133070 0.45 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr2_-_55237484 0.45 ENST00000394609.2
RTN4
reticulon 4
chr1_-_242162375 0.45 ENST00000357246.3
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr2_+_44502630 0.45 ENST00000410056.3
ENST00000409741.1
ENST00000409229.3
SLC3A1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chrX_+_108779004 0.44 ENST00000218004.1
NXT2
nuclear transport factor 2-like export factor 2
chr11_+_1295809 0.42 ENST00000598274.1
AC136297.1
Uncharacterized protein
chr16_+_53469525 0.41 ENST00000544405.2
RBL2
retinoblastoma-like 2 (p130)
chr10_+_695888 0.41 ENST00000441152.2
PRR26
proline rich 26
chr1_-_200379129 0.40 ENST00000367353.1
ZNF281
zinc finger protein 281
chr15_-_52970820 0.40 ENST00000261844.7
ENST00000399202.4
ENST00000562135.1
FAM214A
family with sequence similarity 214, member A
chr17_+_71228537 0.40 ENST00000577615.1
ENST00000585109.1
C17orf80
chromosome 17 open reading frame 80
chrX_+_119737806 0.39 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chr14_+_75536280 0.39 ENST00000238686.8
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr3_-_9291063 0.38 ENST00000383836.3
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr3_-_197300194 0.37 ENST00000358186.2
ENST00000431056.1
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr9_-_39239171 0.37 ENST00000358144.2
CNTNAP3
contactin associated protein-like 3
chr2_+_32390925 0.34 ENST00000440718.1
ENST00000379343.2
ENST00000282587.5
ENST00000435660.1
ENST00000538303.1
ENST00000357055.3
ENST00000406369.1
SLC30A6
solute carrier family 30 (zinc transporter), member 6
chr3_+_153839149 0.34 ENST00000465093.1
ENST00000465817.1
ARHGEF26
Rho guanine nucleotide exchange factor (GEF) 26
chr3_-_186262166 0.34 ENST00000307944.5
CRYGS
crystallin, gamma S
chr17_+_68071389 0.33 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr21_+_17442799 0.33 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
LINC00478
long intergenic non-protein coding RNA 478
chr12_-_110883346 0.30 ENST00000547365.1
ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr9_+_2159850 0.30 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_+_165878100 0.29 ENST00000513876.2
FAM218A
family with sequence similarity 218, member A
chr12_-_118628350 0.28 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr5_+_68860949 0.28 ENST00000507595.1
GTF2H2C
general transcription factor IIH, polypeptide 2C
chr12_+_72061563 0.28 ENST00000551238.1
THAP2
THAP domain containing, apoptosis associated protein 2
chr3_-_32544900 0.27 ENST00000205636.3
CMTM6
CKLF-like MARVEL transmembrane domain containing 6
chr6_+_88117683 0.27 ENST00000369562.4
C6ORF165
UPF0704 protein C6orf165
chr7_+_152456904 0.27 ENST00000537264.1
ACTR3B
ARP3 actin-related protein 3 homolog B (yeast)
chr8_-_125577940 0.26 ENST00000519168.1
ENST00000395508.2
MTSS1
metastasis suppressor 1
chr12_-_118796910 0.26 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr12_-_49581152 0.26 ENST00000550811.1
TUBA1A
tubulin, alpha 1a
chr2_+_179317994 0.26 ENST00000375129.4
DFNB59
deafness, autosomal recessive 59
chr10_-_75226166 0.25 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr2_-_58468437 0.25 ENST00000403676.1
ENST00000427708.2
ENST00000403295.3
ENST00000446381.1
ENST00000417361.1
ENST00000233741.4
ENST00000402135.3
ENST00000540646.1
ENST00000449070.1
FANCL
Fanconi anemia, complementation group L
chr14_-_21567009 0.25 ENST00000556174.1
ENST00000554478.1
ENST00000553980.1
ENST00000421093.2
ZNF219
zinc finger protein 219
chr12_+_100897130 0.25 ENST00000551379.1
ENST00000188403.7
ENST00000551184.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr7_+_152456829 0.24 ENST00000377776.3
ENST00000256001.8
ENST00000397282.2
ACTR3B
ARP3 actin-related protein 3 homolog B (yeast)
chr10_+_18689637 0.24 ENST00000377315.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr3_-_165555200 0.23 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr9_-_71869642 0.23 ENST00000600472.1
AL358113.1
Tight junction protein 2 (Zona occludens 2) isoform 1 variant; Uncharacterized protein
chr9_+_124329336 0.22 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP
DAB2 interacting protein
chr5_-_111093759 0.22 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
NREP
neuronal regeneration related protein
chr10_+_89420706 0.22 ENST00000427144.2
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr12_-_118796971 0.22 ENST00000542902.1
TAOK3
TAO kinase 3
chr20_+_31823792 0.21 ENST00000375413.4
ENST00000354297.4
ENST00000375422.2
BPIFA1
BPI fold containing family A, member 1
chr11_-_63439013 0.21 ENST00000398868.3
ATL3
atlastin GTPase 3
chr11_-_111649015 0.21 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr1_+_62439037 0.21 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr9_-_27005686 0.20 ENST00000380055.5
LRRC19
leucine rich repeat containing 19
chr11_+_18433840 0.20 ENST00000541669.1
ENST00000280704.4
LDHC
lactate dehydrogenase C
chr6_-_41039567 0.20 ENST00000468811.1
OARD1
O-acyl-ADP-ribose deacylase 1
chr12_-_110937351 0.19 ENST00000552130.2
VPS29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr4_+_76649797 0.19 ENST00000538159.1
ENST00000514213.2
USO1
USO1 vesicle transport factor
chr6_-_76072719 0.19 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr17_+_44701402 0.19 ENST00000575068.1
NSF
N-ethylmaleimide-sensitive factor
chr7_-_67162002 0.19 ENST00000420758.1
RP4-736H5.3
RP4-736H5.3
chr2_-_17981462 0.19 ENST00000402989.1
ENST00000428868.1
SMC6
structural maintenance of chromosomes 6
chr17_-_39023462 0.19 ENST00000251643.4
KRT12
keratin 12
chr5_+_136070614 0.19 ENST00000502421.1
CTB-1I21.1
CTB-1I21.1
chr4_+_76649753 0.19 ENST00000603759.1
USO1
USO1 vesicle transport factor
chr2_-_70529180 0.18 ENST00000450256.1
ENST00000037869.3
FAM136A
family with sequence similarity 136, member A
chr6_-_111804905 0.18 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr6_+_3259148 0.17 ENST00000419065.2
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr15_+_43477580 0.17 ENST00000356633.5
CCNDBP1
cyclin D-type binding-protein 1
chr11_+_57480046 0.17 ENST00000378312.4
ENST00000278422.4
TMX2
thioredoxin-related transmembrane protein 2
chr21_+_17792672 0.17 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr14_+_21566980 0.17 ENST00000418511.2
ENST00000554329.2
TMEM253
transmembrane protein 253
chr12_+_54422142 0.17 ENST00000243108.4
HOXC6
homeobox C6
chr5_-_111312622 0.17 ENST00000395634.3
NREP
neuronal regeneration related protein
chr17_+_53342311 0.17 ENST00000226067.5
HLF
hepatic leukemia factor
chr10_+_106034637 0.16 ENST00000401888.2
GSTO2
glutathione S-transferase omega 2
chr22_-_29107919 0.16 ENST00000434810.1
ENST00000456369.1
CHEK2
checkpoint kinase 2
chr11_-_118122996 0.15 ENST00000525386.1
ENST00000527472.1
ENST00000278949.4
MPZL3
myelin protein zero-like 3
chr12_+_116985896 0.15 ENST00000547114.1
RP11-809C9.2
RP11-809C9.2
chr19_+_47616682 0.15 ENST00000594526.1
SAE1
SUMO1 activating enzyme subunit 1
chr2_+_75873902 0.15 ENST00000393909.2
ENST00000358788.6
ENST00000409374.1
MRPL19
mitochondrial ribosomal protein L19
chr6_+_3259122 0.15 ENST00000438998.2
ENST00000380305.4
PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr17_+_57807062 0.15 ENST00000587259.1
VMP1
vacuole membrane protein 1
chrX_+_100878079 0.15 ENST00000471229.2
ARMCX3
armadillo repeat containing, X-linked 3
chr3_-_11623804 0.15 ENST00000451674.2
VGLL4
vestigial like 4 (Drosophila)
chr6_-_150067696 0.15 ENST00000340413.2
ENST00000367403.3
NUP43
nucleoporin 43kDa
chr1_+_170115142 0.15 ENST00000439373.2
METTL11B
methyltransferase like 11B
chr3_-_187455680 0.15 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr17_+_68071458 0.15 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr15_-_44092295 0.15 ENST00000249714.3
ENST00000299969.6
ENST00000319327.6
SERINC4
serine incorporator 4
chr7_-_117512264 0.15 ENST00000454375.1
CTTNBP2
cortactin binding protein 2
chr15_+_75628394 0.14 ENST00000564815.1
ENST00000338995.6
COMMD4
COMM domain containing 4
chr1_-_169703203 0.14 ENST00000333360.7
ENST00000367781.4
ENST00000367782.4
ENST00000367780.4
ENST00000367779.4
SELE
selectin E
chr2_+_36923830 0.14 ENST00000379242.3
ENST00000389975.3
VIT
vitrin
chr1_-_209957882 0.14 ENST00000294811.1
C1orf74
chromosome 1 open reading frame 74
chr2_-_183291741 0.13 ENST00000351439.5
ENST00000409365.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr7_+_55980331 0.13 ENST00000429591.2
ZNF713
zinc finger protein 713
chr15_+_75628232 0.12 ENST00000267935.8
ENST00000567195.1
COMMD4
COMM domain containing 4
chr17_-_5321549 0.12 ENST00000572809.1
NUP88
nucleoporin 88kDa
chr5_+_140514782 0.12 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr14_+_39944025 0.12 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
RP11-111A21.1
chr16_-_67517716 0.12 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chr11_+_85359062 0.11 ENST00000532180.1
TMEM126A
transmembrane protein 126A
chr2_+_128458514 0.11 ENST00000310981.4
SFT2D3
SFT2 domain containing 3
chr7_-_80551671 0.11 ENST00000419255.2
ENST00000544525.1
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr6_+_88106840 0.11 ENST00000369570.4
C6orf164
chromosome 6 open reading frame 164
chr2_+_86669118 0.11 ENST00000427678.1
ENST00000542128.1
KDM3A
lysine (K)-specific demethylase 3A
chr13_-_88463487 0.11 ENST00000606221.1
RP11-471M2.3
RP11-471M2.3
chrX_+_100878112 0.11 ENST00000491568.2
ENST00000479298.1
ARMCX3
armadillo repeat containing, X-linked 3
chr15_-_34331243 0.11 ENST00000306730.3
AVEN
apoptosis, caspase activation inhibitor
chr9_+_125795788 0.10 ENST00000373643.5
RABGAP1
RAB GTPase activating protein 1
chr17_-_14683517 0.10 ENST00000379640.1
AC005863.1
AC005863.1
chr2_-_145275828 0.10 ENST00000392861.2
ENST00000409211.1
ZEB2
zinc finger E-box binding homeobox 2
chr12_+_19358228 0.10 ENST00000424268.1
ENST00000543806.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr12_-_15815626 0.10 ENST00000540613.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr5_+_133562095 0.09 ENST00000602919.1
CTD-2410N18.3
CTD-2410N18.3
chr12_+_58003935 0.09 ENST00000333972.7
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr6_-_170893268 0.09 ENST00000538195.1
PDCD2
programmed cell death 2
chr9_+_136501478 0.09 ENST00000393056.2
ENST00000263611.2
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr2_+_36923933 0.08 ENST00000497382.1
ENST00000404084.1
ENST00000379241.3
ENST00000401530.1
VIT
vitrin
chr8_-_103884640 0.08 ENST00000520402.1
AZIN1
antizyme inhibitor 1
chr2_+_121010370 0.08 ENST00000420510.1
RALB
v-ral simian leukemia viral oncogene homolog B
chr13_+_88325498 0.08 ENST00000400028.3
SLITRK5
SLIT and NTRK-like family, member 5
chr2_-_172087824 0.08 ENST00000521943.1
TLK1
tousled-like kinase 1
chr3_+_155860751 0.08 ENST00000471742.1
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr3_+_12392971 0.08 ENST00000287820.6
PPARG
peroxisome proliferator-activated receptor gamma
chr7_-_27169801 0.07 ENST00000511914.1
HOXA4
homeobox A4
chr1_+_42846443 0.07 ENST00000410070.2
ENST00000431473.3
RIMKLA
ribosomal modification protein rimK-like family member A
chr13_+_20268547 0.07 ENST00000601204.1
AL354808.2
AL354808.2
chr9_+_44867571 0.07 ENST00000377548.2
RP11-160N1.10
RP11-160N1.10
chr5_+_61874562 0.07 ENST00000334994.5
ENST00000409534.1
LRRC70
IPO11
leucine rich repeat containing 70
importin 11
chr1_+_78383813 0.07 ENST00000342754.5
NEXN
nexilin (F actin binding protein)
chr11_+_85359002 0.06 ENST00000528105.1
ENST00000304511.2
TMEM126A
transmembrane protein 126A
chr12_-_118628315 0.06 ENST00000540561.1
TAOK3
TAO kinase 3
chr18_-_52989217 0.06 ENST00000570287.2
TCF4
transcription factor 4
chr20_+_32150140 0.06 ENST00000344201.3
ENST00000346541.3
ENST00000397800.1
ENST00000397798.2
ENST00000492345.1
CBFA2T2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr3_-_33686743 0.06 ENST00000333778.6
ENST00000539981.1
CLASP2
cytoplasmic linker associated protein 2
chr4_-_143227088 0.06 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr2_+_121010324 0.06 ENST00000272519.5
RALB
v-ral simian leukemia viral oncogene homolog B
chr5_+_81601166 0.06 ENST00000439350.1
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr3_-_45837959 0.06 ENST00000353278.4
ENST00000456124.2
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chrX_-_11284095 0.06 ENST00000303025.6
ENST00000534860.1
ARHGAP6
Rho GTPase activating protein 6
chr12_+_54410664 0.05 ENST00000303406.4
HOXC4
homeobox C4
chr2_-_70529126 0.05 ENST00000438759.1
ENST00000430566.1
FAM136A
family with sequence similarity 136, member A
chr5_+_137722255 0.05 ENST00000542866.1
KDM3B
lysine (K)-specific demethylase 3B
chr1_+_84630645 0.05 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr17_-_39623681 0.05 ENST00000225899.3
KRT32
keratin 32
chr16_-_69373396 0.04 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
COG8
component of oligomeric golgi complex 8
chr18_+_66382428 0.04 ENST00000578970.1
ENST00000582371.1
ENST00000584775.1
CCDC102B
coiled-coil domain containing 102B
chr5_+_140571902 0.04 ENST00000239446.4
PCDHB10
protocadherin beta 10
chr12_-_118797475 0.04 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3
TAO kinase 3
chr19_-_58485895 0.04 ENST00000314391.3
C19orf18
chromosome 19 open reading frame 18
chr2_+_152214098 0.04 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr12_-_92539614 0.04 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr3_+_111393501 0.04 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chrX_+_68835911 0.03 ENST00000525810.1
ENST00000527388.1
ENST00000374553.2
ENST00000374552.4
ENST00000338901.3
ENST00000524573.1
EDA
ectodysplasin A
chr10_+_106034884 0.03 ENST00000369707.2
ENST00000429569.2
GSTO2
glutathione S-transferase omega 2

Network of associatons between targets according to the STRING database.

First level regulatory network of DRGX_PROP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:2001190 peptide antigen assembly with MHC class II protein complex(GO:0002503) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.8 0.8 GO:0034759 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759)
0.6 2.3 GO:2000097 negative regulation of lipoprotein oxidation(GO:0034443) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.5 1.6 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.5 6.0 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.4 1.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.4 1.9 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.2 1.0 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.2 2.0 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 0.5 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.2 0.5 GO:0045062 extrathymic T cell selection(GO:0045062)
0.2 0.5 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.1 0.4 GO:0002188 translation reinitiation(GO:0002188)
0.1 1.0 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.7 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.1 0.5 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 0.7 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.2 GO:0019516 lactate oxidation(GO:0019516)
0.1 0.2 GO:2000213 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1 0.3 GO:1903464 negative regulation of mitotic cell cycle DNA replication(GO:1903464)
0.1 0.2 GO:0000103 sulfate assimilation(GO:0000103)
0.1 1.7 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.4 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.5 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.8 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.0 0.3 GO:0030035 microspike assembly(GO:0030035) epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.2 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.0 0.1 GO:0060178 regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
0.0 0.2 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.6 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.3 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.8 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.9 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290) formaldehyde metabolic process(GO:0046292)
0.0 0.1 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:2000230 regulation of cholesterol transporter activity(GO:0060694) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.2 GO:0090487 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.8 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.0 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0060174 pulmonary myocardium development(GO:0003350) limb bud formation(GO:0060174)
0.0 0.1 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.5 GO:0005577 fibrinogen complex(GO:0005577)
0.4 1.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 2.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 1.6 GO:1990357 terminal web(GO:1990357)
0.1 0.7 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.2 GO:1990032 parallel fiber(GO:1990032)
0.1 0.5 GO:0001740 Barr body(GO:0001740)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 2.0 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 1.8 GO:0031526 brush border membrane(GO:0031526)
0.0 0.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.5 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.4 GO:0098576 lumenal side of membrane(GO:0098576)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.2 0.8 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.2 1.6 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 1.0 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.4 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.6 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.2 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 2.0 GO:0005523 tropomyosin binding(GO:0005523)
0.1 2.4 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.2 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.1 0.2 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.1 0.2 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.0 0.5 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 6.0 GO:0051087 chaperone binding(GO:0051087)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0045174 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 2.3 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.3 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.7 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 1.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.0 0.8 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.6 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 2.4 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin