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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for EGR1_EGR4

Z-value: 0.95

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Transcription factors associated with EGR1_EGR4

Gene Symbol Gene ID Gene Info
ENSG00000120738.7 early growth response 1
ENSG00000135625.6 early growth response 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EGR1hg19_v2_chr5_+_137801160_137801179-0.217.9e-01Click!
EGR4hg19_v2_chr2_-_73520667_73520833-0.099.1e-01Click!

Activity profile of EGR1_EGR4 motif

Sorted Z-values of EGR1_EGR4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_77158021 1.16 ENST00000550876.1
zinc finger, DHHC-type containing 17
chr4_-_78740511 0.86 ENST00000504123.1
ENST00000264903.4
ENST00000515441.1
CCR4-NOT transcription complex, subunit 6-like
chr2_-_128145498 0.71 ENST00000409179.2
mitogen-activated protein kinase kinase kinase 2
chr12_+_130822606 0.60 ENST00000546060.1
ENST00000539400.1
piwi-like RNA-mediated gene silencing 1
chr21_+_17102311 0.54 ENST00000285679.6
ENST00000351097.5
ENST00000285681.2
ENST00000400183.2
ubiquitin specific peptidase 25
chr15_-_80263506 0.50 ENST00000335661.6
BCL2-related protein A1
chr2_-_27718052 0.47 ENST00000264703.3
fibronectin type III domain containing 4
chr12_+_1099675 0.47 ENST00000545318.2
ELKS/RAB6-interacting/CAST family member 1
chr10_-_95462265 0.45 ENST00000536233.1
ENST00000359204.4
ENST00000371430.2
ENST00000394100.2
fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1
chr19_-_49371711 0.44 ENST00000355496.5
ENST00000263265.6
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr2_+_155554797 0.42 ENST00000295101.2
potassium inwardly-rectifying channel, subfamily J, member 3
chr3_-_88108212 0.42 ENST00000482016.1
CGG triplet repeat binding protein 1
chr3_-_45267760 0.41 ENST00000503771.1
transmembrane protein 158 (gene/pseudogene)
chr1_+_6845384 0.39 ENST00000303635.7
calmodulin binding transcription activator 1
chr19_+_49617581 0.38 ENST00000391864.3
lin-7 homolog B (C. elegans)
chr1_+_6845578 0.36 ENST00000467404.2
ENST00000439411.2
calmodulin binding transcription activator 1
chr7_-_127032363 0.36 ENST00000393312.1
zinc finger protein 800
chr5_-_176924562 0.35 ENST00000359895.2
ENST00000355572.2
ENST00000355841.2
ENST00000393551.1
ENST00000505074.1
ENST00000356618.4
ENST00000393546.4
PDZ and LIM domain 7 (enigma)
chr1_+_6845497 0.34 ENST00000473578.1
ENST00000557126.1
calmodulin binding transcription activator 1
chr8_-_145060593 0.34 ENST00000313059.5
ENST00000524918.1
ENST00000313028.7
ENST00000525773.1
poly (ADP-ribose) polymerase family, member 10
chr20_+_49348109 0.33 ENST00000396039.1
par-6 family cell polarity regulator beta
chr19_+_47778119 0.32 ENST00000552360.2
proline rich 24
chr19_-_663171 0.32 ENST00000606896.1
ENST00000589762.2
ring finger protein 126
chr1_-_9189229 0.31 ENST00000377411.4
G protein-coupled receptor 157
chr6_+_11537910 0.30 ENST00000543875.1
transmembrane protein 170B
chr8_-_74791051 0.28 ENST00000453587.2
ENST00000602969.1
ENST00000602593.1
ENST00000419880.3
ENST00000517608.1
ubiquitin-conjugating enzyme E2W (putative)
chrX_-_108976521 0.28 ENST00000469796.2
ENST00000502391.1
ENST00000508092.1
ENST00000340800.2
ENST00000348502.6
acyl-CoA synthetase long-chain family member 4
chr19_-_13617037 0.27 ENST00000360228.5
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr6_+_134274322 0.27 ENST00000367871.1
ENST00000237264.4
TBP-like 1
chr20_-_31172598 0.27 ENST00000201961.2
chromosome 20 open reading frame 112
chr14_+_64971438 0.27 ENST00000555321.1
zinc finger and BTB domain containing 1
chr8_-_127570603 0.27 ENST00000304916.3
family with sequence similarity 84, member B
chr19_+_589893 0.27 ENST00000251287.2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr1_-_87379785 0.26 ENST00000401030.3
ENST00000370554.1
Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.
chr5_-_172755056 0.26 ENST00000520648.1
stanniocalcin 2
chr12_+_70760056 0.26 ENST00000258111.4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr2_-_239149300 0.26 ENST00000436051.1
hes family bHLH transcription factor 6
chr6_+_138188351 0.26 ENST00000421450.1
tumor necrosis factor, alpha-induced protein 3
chr19_+_10400615 0.25 ENST00000221980.4
intercellular adhesion molecule 5, telencephalin
chr14_+_102027688 0.24 ENST00000510508.4
ENST00000359323.3
deiodinase, iodothyronine, type III
chr4_+_17579110 0.24 ENST00000606142.1
leucine aminopeptidase 3
chr17_-_36760865 0.24 ENST00000584266.1
SRC kinase signaling inhibitor 1
chr12_+_105724414 0.24 ENST00000443585.1
ENST00000552457.1
ENST00000549893.1
chromosome 12 open reading frame 75
chrX_+_107334895 0.23 ENST00000372232.3
ENST00000345734.3
ENST00000372254.3
autophagy related 4A, cysteine peptidase
chr15_+_41221536 0.23 ENST00000249749.5
delta-like 4 (Drosophila)
chr6_-_4135825 0.23 ENST00000380118.3
ENST00000413766.2
ENST00000361538.2
enoyl-CoA delta isomerase 2
chr5_-_145214893 0.23 ENST00000394450.2
PRELI domain containing 2
chr4_+_26859300 0.22 ENST00000494628.2
stromal interaction molecule 2
chr15_+_74833518 0.22 ENST00000346246.5
AT rich interactive domain 3B (BRIGHT-like)
chr16_+_2588012 0.22 ENST00000354836.5
ENST00000389224.3
3-phosphoinositide dependent protein kinase-1
chr3_-_138048653 0.22 ENST00000460099.1
NME/NM23 family member 9
chr6_+_144471643 0.22 ENST00000367568.4
syntaxin 11
chr6_-_26659913 0.22 ENST00000480036.1
ENST00000415922.2
zinc finger protein 322
chr20_+_55204351 0.21 ENST00000201031.2
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr1_+_185126598 0.21 ENST00000450350.1
SWT1 RNA endoribonuclease homolog (S. cerevisiae)
chr2_+_148778570 0.21 ENST00000407073.1
methyl-CpG binding domain protein 5
chr3_-_194207388 0.21 ENST00000457986.1
ATPase type 13A3
chr3_+_75721428 0.21 ENST00000463183.1
long intergenic non-protein coding RNA 960
chr15_-_80695917 0.21 ENST00000559008.1
Uncharacterized protein
chr4_+_183065793 0.21 ENST00000512480.1
teneurin transmembrane protein 3
chr17_+_57408994 0.21 ENST00000312655.4
yippee-like 2 (Drosophila)
chr20_-_3996165 0.21 ENST00000545616.2
ENST00000358395.6
ring finger protein 24
chr13_-_52027134 0.21 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
integrator complex subunit 6
chr17_+_54671047 0.21 ENST00000332822.4
noggin
chr8_-_102217796 0.21 ENST00000519744.1
ENST00000311212.4
ENST00000521272.1
ENST00000519882.1
zinc finger protein 706
chr17_-_36413133 0.21 ENST00000523089.1
ENST00000312412.4
ENST00000520237.1
TBC1 domain family member 3
chr3_+_170075436 0.20 ENST00000476188.1
ENST00000259119.4
ENST00000426052.2
SKI-like oncogene
chr19_-_663147 0.20 ENST00000606702.1
ring finger protein 126
chr22_+_36784632 0.20 ENST00000424761.1
RP4-633O19__A.1
chr18_+_12948000 0.20 ENST00000585730.1
ENST00000399892.2
ENST00000589446.1
ENST00000587761.1
SEH1-like (S. cerevisiae)
chr2_+_220306745 0.19 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
SPEG complex locus
chr16_-_56458783 0.19 ENST00000563664.1
autocrine motility factor receptor, E3 ubiquitin protein ligase
chr11_+_114310164 0.19 ENST00000544196.1
ENST00000539754.1
ENST00000539275.1
RNA exonuclease 2
chr19_+_35634146 0.19 ENST00000586063.1
ENST00000270310.2
ENST00000588265.1
FXYD domain containing ion transport regulator 7
chr16_-_2185899 0.19 ENST00000262304.4
ENST00000423118.1
polycystic kidney disease 1 (autosomal dominant)
chr2_-_148778258 0.19 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
origin recognition complex, subunit 4
chr20_+_49348081 0.19 ENST00000371610.2
par-6 family cell polarity regulator beta
chr2_+_153191706 0.19 ENST00000288670.9
formin-like 2
chr15_+_91446961 0.19 ENST00000559965.1
mannosidase, alpha, class 2A, member 2
chr4_-_54930790 0.18 ENST00000263921.3
cysteine-rich hydrophobic domain 2
chr19_-_663277 0.18 ENST00000292363.5
ring finger protein 126
chr19_-_54693146 0.18 ENST00000414665.1
ENST00000453320.1
membrane bound O-acyltransferase domain containing 7
chr4_-_103748696 0.18 ENST00000321805.7
ubiquitin-conjugating enzyme E2D 3
chr21_-_38445470 0.18 ENST00000399098.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr6_+_134274354 0.18 ENST00000367869.1
TBP-like 1
chr15_-_64648273 0.18 ENST00000607537.1
ENST00000303052.7
ENST00000303032.6
casein kinase 1, gamma 1
chr15_-_41408409 0.18 ENST00000361937.3
INO80 complex subunit
chr1_-_23694794 0.18 ENST00000374608.3
zinc finger protein 436
chr19_-_14201507 0.18 ENST00000533683.2
sterile alpha motif domain containing 1
chr4_-_819901 0.17 ENST00000304062.6
complexin 1
chr11_-_64512803 0.17 ENST00000377489.1
ENST00000354024.3
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr11_-_72853267 0.17 ENST00000409418.4
FCH and double SH3 domains 2
chr12_-_96794330 0.17 ENST00000261211.3
cyclin-dependent kinase 17
chr11_-_9336117 0.17 ENST00000527813.1
ENST00000533723.1
transmembrane protein 41B
chr22_+_18593446 0.17 ENST00000316027.6
tubulin, alpha 8
chr11_-_64511789 0.17 ENST00000419843.1
ENST00000394430.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr14_+_45553296 0.17 ENST00000355765.6
ENST00000553605.1
pre-mRNA processing factor 39
chr7_-_100808843 0.17 ENST00000249330.2
VGF nerve growth factor inducible
chr15_-_75017711 0.17 ENST00000567032.1
ENST00000564596.1
ENST00000566503.1
ENST00000395049.4
ENST00000395048.2
ENST00000379727.3
cytochrome P450, family 1, subfamily A, polypeptide 1
chr11_+_114310102 0.16 ENST00000265881.5
RNA exonuclease 2
chr7_-_99774945 0.16 ENST00000292377.2
glypican 2
chr7_-_100808394 0.16 ENST00000445482.2
VGF nerve growth factor inducible
chr22_-_30722912 0.16 ENST00000215790.7
TBC1 domain family, member 10A
chr4_-_819880 0.16 ENST00000505203.1
complexin 1
chr1_-_78149041 0.16 ENST00000414381.1
ENST00000370798.1
zinc finger, ZZ-type containing 3
chr22_+_20850171 0.16 ENST00000445987.1
mediator complex subunit 15
chr7_-_33102399 0.16 ENST00000242210.7
5'-nucleotidase, cytosolic IIIA
chr5_+_61602236 0.16 ENST00000514082.1
ENST00000407818.3
kinesin heavy chain member 2A
chr2_+_219724544 0.16 ENST00000233948.3
wingless-type MMTV integration site family, member 6
chr17_+_72428266 0.16 ENST00000582473.1
G protein-coupled receptor, family C, group 5, member C
chr7_-_33102338 0.16 ENST00000610140.1
5'-nucleotidase, cytosolic IIIA
chr2_+_99758161 0.16 ENST00000409684.1
Uncharacterized protein C2orf15
chr12_-_96794143 0.16 ENST00000543119.2
cyclin-dependent kinase 17
chr11_-_627143 0.16 ENST00000176195.3
secretin
chr11_-_95523500 0.16 ENST00000540054.1
family with sequence similarity 76, member B
chr19_-_36870087 0.16 ENST00000270001.7
ZFP14 zinc finger protein
chr19_-_50836762 0.16 ENST00000474951.1
ENST00000391818.2
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr12_-_85306594 0.16 ENST00000266682.5
solute carrier family 6 (neutral amino acid transporter), member 15
chr19_-_46145696 0.16 ENST00000588172.1
echinoderm microtubule associated protein like 2
chr4_+_17578815 0.16 ENST00000226299.4
leucine aminopeptidase 3
chr10_-_27444143 0.15 ENST00000477432.1
YME1-like 1 ATPase
chr8_+_145321517 0.15 ENST00000340210.1
scleraxis homolog B (mouse)
chr6_+_19837592 0.15 ENST00000378700.3
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr19_-_56988677 0.15 ENST00000504904.3
ENST00000292069.6
zinc finger protein 667
chr14_-_69445968 0.15 ENST00000438964.2
actinin, alpha 1
chr3_+_113666748 0.15 ENST00000330212.3
ENST00000498275.1
zinc finger, DHHC-type containing 23
chrX_-_154033793 0.15 ENST00000369534.3
ENST00000413259.3
membrane protein, palmitoylated 1, 55kDa
chr11_+_1151573 0.15 ENST00000534821.1
ENST00000356191.2
mucin 5AC, oligomeric mucus/gel-forming
chr2_-_26101314 0.15 ENST00000336112.4
ENST00000272341.4
additional sex combs like 2 (Drosophila)
chrX_-_101186981 0.15 ENST00000458570.1
zinc finger, matrin-type 1
chr17_-_6947225 0.15 ENST00000574600.1
ENST00000308009.1
ENST00000447225.1
solute carrier family 16, member 11
chr5_-_176923803 0.15 ENST00000506161.1
PDZ and LIM domain 7 (enigma)
chr15_-_71146347 0.15 ENST00000559140.2
La ribonucleoprotein domain family, member 6
chr6_-_4135693 0.15 ENST00000495548.1
ENST00000380125.2
ENST00000465828.1
enoyl-CoA delta isomerase 2
chr15_-_71146460 0.15 ENST00000344870.4
La ribonucleoprotein domain family, member 6
chr1_-_197744763 0.15 ENST00000422998.1
DENN/MADD domain containing 1B
chr3_+_100120441 0.15 ENST00000489752.1
leukemia NUP98 fusion partner 1
chr2_-_148778323 0.15 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
origin recognition complex, subunit 4
chr18_-_51750948 0.15 ENST00000583046.1
ENST00000398398.2
methyl-CpG binding domain protein 2
chr2_-_98612379 0.14 ENST00000425805.2
transmembrane protein 131
chr11_+_100558384 0.14 ENST00000524892.2
ENST00000298815.8
Rho GTPase activating protein 42
chr16_+_2587998 0.14 ENST00000441549.3
ENST00000268673.7
3-phosphoinositide dependent protein kinase-1
chr19_-_39360561 0.14 ENST00000593809.1
ENST00000593424.1
Ras and Rab interactor-like
chr16_+_2564254 0.14 ENST00000565223.1
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr14_-_77495007 0.14 ENST00000238647.3
interferon regulatory factor 2 binding protein-like
chr19_-_44174330 0.14 ENST00000340093.3
plasminogen activator, urokinase receptor
chr16_+_66461175 0.14 ENST00000536005.2
ENST00000299694.8
ENST00000561796.1
brain expressed, associated with NEDD4, 1
chr16_-_3086927 0.14 ENST00000572449.1
coiled-coil domain containing 64B
chrX_+_107068959 0.14 ENST00000451923.1
midline 2
chr11_-_64512273 0.14 ENST00000377497.3
ENST00000377487.1
ENST00000430645.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr4_-_90758227 0.14 ENST00000506691.1
ENST00000394986.1
ENST00000506244.1
ENST00000394989.2
ENST00000394991.3
synuclein, alpha (non A4 component of amyloid precursor)
chr4_-_185395191 0.14 ENST00000510814.1
ENST00000507523.1
ENST00000506230.1
interferon regulatory factor 2
chr12_+_130822417 0.14 ENST00000245255.3
piwi-like RNA-mediated gene silencing 1
chr16_+_57662596 0.14 ENST00000567397.1
ENST00000568979.1
G protein-coupled receptor 56
chr10_-_112678692 0.14 ENST00000605742.1
BBSome interacting protein 1
chr14_-_64971288 0.14 ENST00000394715.1
zinc finger and BTB domain containing 25
chr2_+_42396574 0.14 ENST00000401738.3
echinoderm microtubule associated protein like 4
chr2_+_196522032 0.14 ENST00000418005.1
solute carrier family 39 (zinc transporter), member 10
chr22_-_30722866 0.14 ENST00000403477.3
TBC1 domain family, member 10A
chr1_-_117113596 0.14 ENST00000457047.2
ENST00000369489.5
ENST00000369487.3
CD58 molecule
chr11_+_35965531 0.13 ENST00000528989.1
ENST00000524419.1
ENST00000315571.5
low density lipoprotein receptor class A domain containing 3
chr7_-_100493482 0.13 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
acetylcholinesterase (Yt blood group)
chr2_-_98612350 0.13 ENST00000186436.5
transmembrane protein 131
chr6_+_17281802 0.13 ENST00000509686.1
RNA binding motif protein 24
chrX_-_108976449 0.13 ENST00000469857.1
acyl-CoA synthetase long-chain family member 4
chr8_-_63951730 0.13 ENST00000260118.6
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
chr10_+_49514698 0.13 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
mitogen-activated protein kinase 8
chr17_-_4269920 0.13 ENST00000572484.1
ubiquitin-conjugating enzyme E2G 1
chr22_+_38597889 0.13 ENST00000338483.2
ENST00000538320.1
ENST00000538999.1
ENST00000441709.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr1_-_26147149 0.13 ENST00000536896.1
Uncharacterized protein
chr5_+_149865377 0.13 ENST00000522491.1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr16_+_3070313 0.13 ENST00000326577.4
tumor necrosis factor receptor superfamily, member 12A
chr7_+_100860949 0.13 ENST00000305105.2
zinc finger, HIT-type containing 1
chr6_-_30128657 0.13 ENST00000449742.2
ENST00000376704.3
tripartite motif containing 10
chr10_+_102505468 0.13 ENST00000361791.3
ENST00000355243.3
ENST00000428433.1
ENST00000370296.2
paired box 2
chr14_+_91709103 0.13 ENST00000553725.1
HCG1816139; Uncharacterized protein
chr11_-_64512469 0.13 ENST00000377485.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr15_-_41408339 0.12 ENST00000401393.3
INO80 complex subunit
chr6_-_2876744 0.12 ENST00000420981.2
RP11-420G6.4
chr6_-_137540477 0.12 ENST00000367735.2
ENST00000367739.4
ENST00000458076.1
ENST00000414770.1
interferon gamma receptor 1
chr2_+_61108650 0.12 ENST00000295025.8
v-rel avian reticuloendotheliosis viral oncogene homolog
chr1_-_35395178 0.12 ENST00000373347.1
discs, large (Drosophila) homolog-associated protein 3
chr1_+_65886244 0.12 ENST00000344610.8
leptin receptor
chr22_-_30970498 0.12 ENST00000431313.1
galactose-3-O-sulfotransferase 1
chrX_-_108976410 0.12 ENST00000504980.1
acyl-CoA synthetase long-chain family member 4
chrX_+_135229600 0.12 ENST00000370690.3
four and a half LIM domains 1
chr11_+_114310237 0.12 ENST00000539119.1
RNA exonuclease 2
chr8_-_101322132 0.12 ENST00000523481.1
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr6_+_35420091 0.12 ENST00000229769.2
Fanconi anemia, complementation group E
chr14_+_55493920 0.12 ENST00000395472.2
ENST00000555846.1
suppressor of cytokine signaling 4
chr7_+_95401877 0.12 ENST00000524053.1
ENST00000324972.6
ENST00000537881.1
ENST00000437599.1
ENST00000359388.4
ENST00000413338.1
dynein, cytoplasmic 1, intermediate chain 1
chr1_+_23695680 0.12 ENST00000454117.1
ENST00000335648.3
ENST00000518821.1
ENST00000437367.2
chromosome 1 open reading frame 213
chr4_-_82393052 0.12 ENST00000335927.7
ENST00000504863.1
ENST00000264400.2
RasGEF domain family, member 1B
chr1_-_41328018 0.12 ENST00000372638.2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr12_+_117348742 0.12 ENST00000309909.5
ENST00000455858.2
F-box and WD repeat domain containing 8
chr1_+_65886326 0.12 ENST00000371059.3
ENST00000371060.3
ENST00000349533.6
ENST00000406510.3
leptin receptor
chr12_+_12510352 0.12 ENST00000298571.6
loss of heterozygosity, 12, chromosomal region 1
chr2_-_122494487 0.12 ENST00000451734.1
ENST00000285814.4
nucleolar protein interacting with the FHA domain of MKI67
chr12_+_57984965 0.12 ENST00000540759.2
ENST00000551772.1
ENST00000550465.1
ENST00000354947.5
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr6_-_139308777 0.12 ENST00000529597.1
ENST00000415951.2
ENST00000367663.4
ENST00000409812.2
RALBP1 associated Eps domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of EGR1_EGR4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0071629 cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071629)
0.2 0.5 GO:2000349 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.1 0.7 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 1.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.3 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1 0.3 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.1 0.2 GO:0033319 UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320)
0.1 0.3 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.1 0.2 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.5 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 0.4 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1 0.2 GO:0017143 insecticide metabolic process(GO:0017143)
0.1 1.2 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 0.2 GO:0003168 Purkinje myocyte differentiation(GO:0003168) cardiac pacemaker cell fate commitment(GO:0060927) atrioventricular node cell fate commitment(GO:0060929)
0.1 0.2 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.0 0.2 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.0 0.4 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.2 GO:0061074 regulation of neural retina development(GO:0061074)
0.0 0.3 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.2 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.3 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0 0.2 GO:0060825 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.0 0.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.1 GO:0060733 regulation of eIF2 alpha phosphorylation by amino acid starvation(GO:0060733) regulation of translational initiation in response to starvation(GO:0071262) positive regulation of translational initiation in response to starvation(GO:0071264)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.1 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.2 GO:0051621 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.2 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.3 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.2 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.1 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.0 0.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.2 GO:0015692 lead ion transport(GO:0015692)
0.0 0.1 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.1 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 0.2 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.2 GO:0030421 defecation(GO:0030421)
0.0 0.1 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.0 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.0 0.1 GO:0072708 response to sorbitol(GO:0072708)
0.0 0.1 GO:1903911 positive regulation of receptor clustering(GO:1903911)
0.0 0.0 GO:0045210 FasL biosynthetic process(GO:0045210)
0.0 0.1 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.1 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.5 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.0 0.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.3 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.2 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.3 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.1 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.1 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.0 0.5 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.1 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.1 GO:1901656 glycoside transport(GO:1901656)
0.0 0.1 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.1 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.3 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.0 0.3 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.2 GO:0060717 chorion development(GO:0060717)
0.0 0.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0032796 uropod organization(GO:0032796)
0.0 0.0 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.0 0.4 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:0097168 mesenchymal stem cell proliferation(GO:0097168) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.2 GO:0015820 leucine transport(GO:0015820)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.1 GO:0051272 positive regulation of cellular component movement(GO:0051272)
0.0 0.0 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.1 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.1 GO:0043387 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.0 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.2 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.2 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.0 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.5 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.2 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.0 GO:2000656 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.0 0.0 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.0 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.0 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.0 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.0 0.2 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.1 GO:0042713 sperm ejaculation(GO:0042713) Sertoli cell proliferation(GO:0060011)
0.0 0.4 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.3 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.0 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.0 0.1 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.0 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.0 0.1 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.0 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.0 0.8 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.1 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0007135 meiosis II(GO:0007135)
0.0 0.0 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.1 GO:0060539 diaphragm development(GO:0060539)
0.0 0.0 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.0 GO:0035113 embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.2 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.1 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.1 GO:0035966 response to topologically incorrect protein(GO:0035966)
0.0 0.0 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.0 GO:0090187 positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of pancreatic juice secretion(GO:0090187) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.0 0.1 GO:1902164 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0030862 positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.5 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.7 GO:0033391 chromatoid body(GO:0033391)
0.0 0.4 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.2 GO:0002133 polycystin complex(GO:0002133)
0.0 0.5 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.2 GO:0070701 mucus layer(GO:0070701)
0.0 0.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.0 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0098844 postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.1 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.0 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.0 GO:0032302 MutSbeta complex(GO:0032302)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 0.5 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.0 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.7 GO:0034584 piRNA binding(GO:0034584)
0.1 0.5 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.4 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.1 0.4 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 0.4 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1 0.2 GO:0048040 UDP-glucuronate decarboxylase activity(GO:0048040)
0.1 0.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 0.3 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.2 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.1 1.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.2 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208) ceramide binding(GO:0097001)
0.0 1.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 0.2 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.1 GO:0004913 interleukin-4 receptor activity(GO:0004913)
0.0 0.2 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.3 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.3 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.2 GO:0010736 serum response element binding(GO:0010736)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 1.1 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.4 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.1 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:0004513 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.0 0.3 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.1 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.4 GO:0051400 BH domain binding(GO:0051400)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.5 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 0.0 GO:0000406 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.0 0.1 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.2 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.0 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.0 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.0 0.0 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.7 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.1 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.0 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex