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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for EMX2

Z-value: 2.00

Motif logo

Transcription factors associated with EMX2

Gene Symbol Gene ID Gene Info
ENSG00000170370.10 empty spiracles homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EMX2hg19_v2_chr10_+_119302508_119302559-0.703.0e-01Click!

Activity profile of EMX2 motif

Sorted Z-values of EMX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_54466179 4.46 ENST00000270458.2
calcium channel, voltage-dependent, gamma subunit 8
chr11_+_5710919 3.18 ENST00000379965.3
ENST00000425490.1
tripartite motif containing 22
chr10_+_91092241 3.07 ENST00000371811.4
interferon-induced protein with tetratricopeptide repeats 3
chr11_-_327537 2.76 ENST00000602735.1
interferon induced transmembrane protein 3
chr1_+_79115503 2.49 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
interferon-induced protein 44
chr15_+_63188009 1.68 ENST00000557900.1
RP11-1069G10.2
chr11_-_104905840 1.64 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr2_+_228736335 1.60 ENST00000440997.1
ENST00000545118.1
dynein assembly factor with WDR repeat domains 1
chr4_-_89205705 1.45 ENST00000295908.7
ENST00000510548.2
ENST00000508256.1
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr15_+_101417919 1.42 ENST00000561338.1
aldehyde dehydrogenase 1 family, member A3
chr17_-_71223839 1.40 ENST00000579872.1
ENST00000580032.1
family with sequence similarity 104, member A
chr4_-_120243545 1.31 ENST00000274024.3
fatty acid binding protein 2, intestinal
chrX_+_78003204 1.21 ENST00000435339.3
ENST00000514744.1
lysophosphatidic acid receptor 4
chr11_-_18258342 1.19 ENST00000278222.4
serum amyloid A4, constitutive
chr10_-_90611566 1.16 ENST00000371930.4
ankyrin repeat domain 22
chr22_+_50981079 1.13 ENST00000609268.1
CTA-384D8.34
chr18_+_61637159 1.08 ENST00000397985.2
ENST00000353706.2
ENST00000542677.1
ENST00000397988.3
ENST00000448851.1
serpin peptidase inhibitor, clade B (ovalbumin), member 8
chr12_-_10007448 1.07 ENST00000538152.1
C-type lectin domain family 2, member B
chr11_-_104916034 1.03 ENST00000528513.1
ENST00000375706.2
ENST00000375704.3
caspase recruitment domain family, member 16
chr8_-_87242589 0.89 ENST00000419776.2
ENST00000297524.3
solute carrier family 7 (anionic amino acid transporter), member 13
chr3_-_108248169 0.88 ENST00000273353.3
myosin, heavy chain 15
chr4_-_89205879 0.86 ENST00000608933.1
ENST00000315194.4
ENST00000514204.1
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr10_-_79397740 0.85 ENST00000372440.1
ENST00000480683.1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr12_-_123187890 0.80 ENST00000328880.5
hydroxycarboxylic acid receptor 2
chr11_-_104972158 0.79 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr11_-_63376013 0.77 ENST00000540943.1
phospholipase A2, group XVI
chr5_-_55412774 0.77 ENST00000434982.2
ankyrin repeat domain 55
chr3_-_48956818 0.76 ENST00000408959.2
ariadne homolog 2 opposite strand
chr15_-_78913628 0.74 ENST00000348639.3
cholinergic receptor, nicotinic, alpha 3 (neuronal)
chr9_-_21368075 0.74 ENST00000449498.1
interferon, alpha 13
chr1_-_92952433 0.72 ENST00000294702.5
growth factor independent 1 transcription repressor
chr15_-_59500973 0.68 ENST00000560749.1
myosin IE
chr11_-_74800799 0.68 ENST00000305159.3
olfactory receptor, family 2, subfamily AT, member 4
chr5_+_34757309 0.67 ENST00000397449.1
retinoic acid induced 14
chr4_-_74864386 0.66 ENST00000296027.4
chemokine (C-X-C motif) ligand 5
chr12_+_28605426 0.66 ENST00000542801.1
coiled-coil domain containing 91
chr8_-_40200903 0.65 ENST00000522486.1
CTA-392C11.1
chr2_-_198540751 0.64 ENST00000429081.1
raftlin family member 2
chr22_+_39966758 0.63 ENST00000407673.1
ENST00000401624.1
ENST00000404898.1
ENST00000402142.3
ENST00000336649.4
ENST00000400164.3
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr17_-_39093672 0.63 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
keratin 23 (histone deacetylase inducible)
chr6_-_134639180 0.62 ENST00000367858.5
serum/glucocorticoid regulated kinase 1
chr8_+_119294456 0.61 ENST00000366457.2
Uncharacterized protein
chr12_+_25055243 0.61 ENST00000599478.1
Protein 101060047
chr1_+_192778161 0.60 ENST00000235382.5
regulator of G-protein signaling 2, 24kDa
chr6_+_34725181 0.60 ENST00000244520.5
small nuclear ribonucleoprotein polypeptide C
chrX_+_100224676 0.59 ENST00000450049.2
ADP-ribosylation factor-like 13A
chr5_-_58571935 0.59 ENST00000503258.1
phosphodiesterase 4D, cAMP-specific
chr2_-_207082748 0.58 ENST00000407325.2
ENST00000411719.1
G protein-coupled receptor 1
chr17_+_62461569 0.58 ENST00000603557.1
ENST00000605096.1
mast cell immunoglobulin-like receptor 1
chr15_-_41166414 0.57 ENST00000220507.4
ras homolog family member V
chr6_+_27833034 0.56 ENST00000357320.2
histone cluster 1, H2al
chr11_-_46113756 0.55 ENST00000531959.1
PHD finger protein 21A
chr8_-_40200877 0.55 ENST00000521030.1
CTA-392C11.1
chr5_-_140013275 0.55 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14 molecule
chr5_+_179135246 0.55 ENST00000508787.1
calnexin
chr12_+_93096619 0.53 ENST00000397833.3
chromosome 12 open reading frame 74
chr5_-_140013224 0.53 ENST00000498971.2
CD14 molecule
chr12_+_1099675 0.52 ENST00000545318.2
ELKS/RAB6-interacting/CAST family member 1
chr5_-_94417186 0.52 ENST00000312216.8
ENST00000512425.1
multiple C2 domains, transmembrane 1
chr2_+_122494676 0.52 ENST00000455432.1
translin
chr12_+_93096759 0.52 ENST00000544406.2
chromosome 12 open reading frame 74
chr17_-_34503867 0.51 ENST00000589443.1
ENST00000454519.3
ENST00000586369.1
TBC1 domain family, member 3B
chr14_+_52164820 0.51 ENST00000554167.1
FERM domain containing 6
chr12_-_58220078 0.50 ENST00000549039.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr14_+_31959154 0.50 ENST00000550005.1
nucleotide binding protein-like
chr2_-_99917639 0.49 ENST00000308528.4
lysozyme G-like 1
chr15_+_64680003 0.49 ENST00000261884.3
thyroid hormone receptor interactor 4
chr1_-_35450897 0.49 ENST00000373337.3
ZMYM6 neighbor
chr16_+_22524844 0.48 ENST00000538606.1
ENST00000424340.1
ENST00000517539.1
ENST00000528249.1
nuclear pore complex interacting protein family, member B5
chr12_+_60083118 0.48 ENST00000261187.4
ENST00000543448.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr1_-_110283660 0.46 ENST00000361066.2
glutathione S-transferase mu 3 (brain)
chr12_-_22063787 0.46 ENST00000544039.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr1_+_151253991 0.45 ENST00000443959.1
zinc finger protein 687
chr1_-_190446759 0.45 ENST00000367462.3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr2_+_39117010 0.45 ENST00000409978.1
Rho guanine nucleotide exchange factor (GEF) 33
chr2_+_56179262 0.45 ENST00000606639.1
RP11-481J13.1
chr2_+_32502952 0.44 ENST00000238831.4
Yip1 domain family, member 4
chr15_-_34635314 0.44 ENST00000557912.1
ENST00000328848.4
NOP10 ribonucleoprotein
chr1_+_36549676 0.44 ENST00000207457.3
tektin 2 (testicular)
chr20_-_45530365 0.44 ENST00000414085.1
RP11-323C15.2
chrX_+_36254051 0.43 ENST00000378657.4
chromosome X open reading frame 30
chr16_+_15489603 0.43 ENST00000568766.1
ENST00000287594.7
Uncharacterized protein
MPV17 mitochondrial membrane protein-like
chr10_-_21186144 0.43 ENST00000377119.1
nebulette
chr8_-_74495065 0.43 ENST00000523533.1
staufen double-stranded RNA binding protein 2
chr3_+_38080691 0.43 ENST00000308059.6
ENST00000346219.3
ENST00000452631.2
deleted in lung and esophageal cancer 1
chr4_-_72649763 0.43 ENST00000513476.1
group-specific component (vitamin D binding protein)
chr4_+_74347400 0.42 ENST00000226355.3
afamin
chr14_+_45464658 0.42 ENST00000555874.1
family with sequence similarity 179, member B
chrX_+_47444613 0.41 ENST00000445623.1
TIMP metallopeptidase inhibitor 1
chr11_-_128894053 0.41 ENST00000392657.3
Rho GTPase activating protein 32
chr8_+_30244580 0.41 ENST00000523115.1
ENST00000519647.1
RNA binding protein with multiple splicing
chr3_-_109056419 0.41 ENST00000335658.6
developmental pluripotency associated 4
chr5_-_173217931 0.41 ENST00000522731.1
CTB-43E15.4
chr16_-_29415350 0.40 ENST00000524087.1
nuclear pore complex interacting protein family, member B11
chr16_-_21868978 0.40 ENST00000357370.5
ENST00000451409.1
ENST00000341400.7
ENST00000518761.4
nuclear pore complex interacting protein family, member B4
chr11_-_107729887 0.40 ENST00000525815.1
solute carrier family 35, member F2
chr22_+_45725524 0.40 ENST00000405548.3
family with sequence similarity 118, member A
chr1_+_111773349 0.39 ENST00000533831.2
chitinase 3-like 2
chrM_+_10758 0.39 ENST00000361381.2
mitochondrially encoded NADH dehydrogenase 4
chr11_+_47293795 0.39 ENST00000422579.1
MAP-kinase activating death domain
chr1_+_225600404 0.39 ENST00000366845.2
AC092811.1
chr4_+_74702214 0.38 ENST00000226317.5
ENST00000515050.1
chemokine (C-X-C motif) ligand 6
chrX_+_36053908 0.38 ENST00000378660.2
calponin homology domain containing 2
chr2_+_234826016 0.37 ENST00000324695.4
ENST00000433712.2
transient receptor potential cation channel, subfamily M, member 8
chr4_-_185694872 0.37 ENST00000505492.1
acyl-CoA synthetase long-chain family member 1
chr7_-_73153178 0.37 ENST00000437775.2
ENST00000222800.3
abhydrolase domain containing 11
chr5_+_115358088 0.37 ENST00000600981.3
CTD-2287O16.3
chr9_+_71986182 0.37 ENST00000303068.7
family with sequence similarity 189, member A2
chr5_-_94417314 0.36 ENST00000505208.1
multiple C2 domains, transmembrane 1
chr11_+_10476851 0.36 ENST00000396553.2
adenosine monophosphate deaminase 3
chr18_+_616672 0.36 ENST00000338387.7
clusterin-like 1 (retinal)
chrX_+_77359726 0.35 ENST00000442431.1
phosphoglycerate kinase 1
chr10_+_15074190 0.35 ENST00000428897.1
ENST00000413672.1
oleoyl-ACP hydrolase
chr1_+_26496362 0.35 ENST00000374266.5
ENST00000270812.5
zinc finger protein 593
chr16_-_21436459 0.35 ENST00000448012.2
ENST00000504841.2
ENST00000419180.2
nuclear pore complex interacting protein family, member B3
chr1_-_139379 0.35 ENST00000423372.3
Uncharacterized protein
chr20_+_36405665 0.35 ENST00000373469.1
catenin, beta like 1
chr8_-_133687813 0.34 ENST00000250173.1
ENST00000519595.1
leucine rich repeat containing 6
chr3_+_132316081 0.34 ENST00000249887.2
atypical chemokine receptor 4
chr13_+_108921977 0.33 ENST00000430559.1
ENST00000375887.4
tumor necrosis factor (ligand) superfamily, member 13b
chr16_+_74330673 0.33 ENST00000219313.4
ENST00000540379.1
ENST00000567958.1
ENST00000568615.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr12_+_78359999 0.33 ENST00000550503.1
neuron navigator 3
chr20_-_1447547 0.32 ENST00000476071.1
NSFL1 (p97) cofactor (p47)
chr1_+_235530675 0.32 ENST00000366601.3
ENST00000406207.1
ENST00000543662.1
tubulin folding cofactor E
chr6_+_110501621 0.32 ENST00000368930.1
ENST00000307731.1
cell division cycle 40
chr3_+_37441062 0.31 ENST00000426078.1
chromosome 3 open reading frame 35
chr12_+_59989918 0.31 ENST00000547379.1
ENST00000549465.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr3_-_52719546 0.31 ENST00000439181.1
ENST00000449505.1
polybromo 1
chr6_+_34725263 0.30 ENST00000374018.1
ENST00000374017.3
small nuclear ribonucleoprotein polypeptide C
chr17_+_42422662 0.30 ENST00000593167.1
ENST00000585512.1
ENST00000591740.1
ENST00000592783.1
ENST00000587387.1
ENST00000588237.1
ENST00000589265.1
granulin
chr6_-_112081113 0.30 ENST00000517419.1
FYN oncogene related to SRC, FGR, YES
chr5_-_94417339 0.30 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
multiple C2 domains, transmembrane 1
chr4_+_41540160 0.30 ENST00000503057.1
ENST00000511496.1
LIM and calponin homology domains 1
chr17_+_5031687 0.30 ENST00000250066.6
ENST00000304328.5
ubiquitin specific peptidase 6 (Tre-2 oncogene)
chrX_+_77359671 0.29 ENST00000373316.4
phosphoglycerate kinase 1
chr20_-_1447467 0.29 ENST00000353088.2
ENST00000350991.4
NSFL1 (p97) cofactor (p47)
chr5_-_140013241 0.29 ENST00000519715.1
CD14 molecule
chr2_+_105050794 0.29 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
long intergenic non-protein coding RNA 1102
chr3_+_140981456 0.29 ENST00000504264.1
acid phosphatase-like 2
chr4_-_168155169 0.29 ENST00000534949.1
ENST00000535728.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr11_-_107729287 0.29 ENST00000375682.4
solute carrier family 35, member F2
chr16_+_28648975 0.28 ENST00000529716.1
nuclear pore complex interacting protein family, member B8
chr17_-_34757039 0.28 ENST00000455054.2
ENST00000308078.7
TBC1 domain family, member 3H
TBC1 domain family, member 3C
chr1_+_234765057 0.28 ENST00000429269.1
long intergenic non-protein coding RNA 184
chr10_-_79398250 0.28 ENST00000286627.5
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr3_-_151047327 0.28 ENST00000325602.5
purinergic receptor P2Y, G-protein coupled, 13
chr2_-_39456673 0.28 ENST00000378803.1
ENST00000395035.3
cyclin-dependent kinase-like 4
chr3_-_186288097 0.28 ENST00000446782.1
TBCC domain containing 1
chr16_+_28763108 0.28 ENST00000357796.3
ENST00000550983.1
nuclear pore complex interacting protein family, member B9
chr12_+_10366223 0.27 ENST00000545290.1
GABA(A) receptor-associated protein like 1
chr2_-_99871570 0.27 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
lysozyme G-like 2
chr4_+_56212505 0.27 ENST00000505210.1
steroid 5 alpha-reductase 3
chr19_-_43969796 0.27 ENST00000244333.3
LY6/PLAUR domain containing 3
chr15_-_99057551 0.27 ENST00000558256.1
family with sequence similarity 169, member B
chr14_-_47351391 0.27 ENST00000399222.3
MAM domain containing glycosylphosphatidylinositol anchor 2
chr17_+_42422637 0.27 ENST00000053867.3
ENST00000588143.1
granulin
chr16_-_28374829 0.27 ENST00000532254.1
nuclear pore complex interacting protein family, member B6
chr16_+_82068873 0.27 ENST00000566213.1
hydroxysteroid (17-beta) dehydrogenase 2
chr3_+_52245458 0.27 ENST00000459884.1
aminolevulinate, delta-, synthase 1
chr4_+_26344754 0.26 ENST00000515573.1
recombination signal binding protein for immunoglobulin kappa J region
chr16_-_29479154 0.25 ENST00000549950.1
Uncharacterized protein
chr1_+_56046710 0.25 ENST00000422374.1
RP11-466L17.1
chr9_-_100684845 0.25 ENST00000375119.3
chromosome 9 open reading frame 156
chr16_+_69599861 0.25 ENST00000354436.2
nuclear factor of activated T-cells 5, tonicity-responsive
chr11_-_26593649 0.25 ENST00000455601.2
mucin 15, cell surface associated
chr3_-_20053741 0.25 ENST00000389050.4
protein phosphatase 2C-like domain containing 1
chr1_-_212588157 0.25 ENST00000261455.4
ENST00000535273.1
transmembrane protein 206
chr7_+_90338712 0.25 ENST00000265741.3
ENST00000406263.1
cyclin-dependent kinase 14
chr18_+_29769978 0.25 ENST00000269202.6
ENST00000581447.1
meprin A, beta
chr7_+_13141010 0.24 ENST00000443947.1
AC011288.2
chr3_+_11314099 0.24 ENST00000446450.2
ENST00000354956.5
ENST00000354449.3
ENST00000419112.1
autophagy related 7
chr4_-_122854612 0.24 ENST00000264811.5
transient receptor potential cation channel, subfamily C, member 3
chr16_+_11038403 0.24 ENST00000409552.3
C-type lectin domain family 16, member A
chr1_+_15668240 0.24 ENST00000444385.1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr3_-_37216055 0.24 ENST00000336686.4
leucine rich repeat (in FLII) interacting protein 2
chr9_+_71944241 0.24 ENST00000257515.8
family with sequence similarity 189, member A2
chr18_+_21693306 0.24 ENST00000540918.2
tetratricopeptide repeat domain 39C
chr11_+_122709200 0.24 ENST00000227348.4
cytotoxic and regulatory T cell molecule
chr15_+_84115868 0.24 ENST00000427482.2
SH3-domain GRB2-like 3
chr4_+_56212270 0.23 ENST00000264228.4
steroid 5 alpha-reductase 3
chr13_-_30880979 0.23 ENST00000414289.1
katanin p60 subunit A-like 1
chr19_-_37697976 0.23 ENST00000588873.1
Uncharacterized protein; Zinc finger protein 585B
chr14_-_47812321 0.23 ENST00000357362.3
ENST00000486952.2
ENST00000426342.1
MAM domain containing glycosylphosphatidylinositol anchor 2
chr12_+_101988774 0.23 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
myosin binding protein C, slow type
chr2_+_74153953 0.23 ENST00000264093.4
ENST00000348222.1
deoxyguanosine kinase
chr3_+_113616317 0.23 ENST00000440446.2
ENST00000488680.1
GRAM domain containing 1C
chr16_+_11038345 0.23 ENST00000409790.1
C-type lectin domain family 16, member A
chr1_+_244998918 0.23 ENST00000366528.3
COX20 cytochrome C oxidase assembly factor
chr7_-_101272576 0.23 ENST00000223167.4
myosin, light chain 10, regulatory
chr19_-_41388657 0.22 ENST00000301146.4
ENST00000291764.3
cytochrome P450, family 2, subfamily A, polypeptide 7
chr6_-_76782371 0.22 ENST00000369950.3
ENST00000369963.3
interphotoreceptor matrix proteoglycan 1
chrX_+_154254960 0.22 ENST00000369498.3
FUN14 domain containing 2
chr10_+_122610853 0.22 ENST00000604585.1
WD repeat domain 11
chr12_+_110011571 0.22 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
mevalonate kinase
chr12_-_53171128 0.22 ENST00000332411.2
keratin 76
chr10_-_79398127 0.22 ENST00000372443.1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr1_+_174844645 0.22 ENST00000486220.1
RAB GTPase activating protein 1-like
chr4_+_158493642 0.22 ENST00000507108.1
ENST00000455598.1
ENST00000509450.1
RP11-364P22.1
chr19_+_14693888 0.21 ENST00000547437.1
ENST00000397439.2
ENST00000417570.1
C-type lectin domain family 17, member A
chr2_+_157330081 0.21 ENST00000409674.1
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)

Network of associatons between targets according to the STRING database.

First level regulatory network of EMX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.5 1.4 GO:0060166 olfactory pit development(GO:0060166)
0.2 0.7 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.2 3.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.2 1.4 GO:0071725 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.2 0.8 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.2 4.5 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.4 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 2.8 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 1.0 GO:0071494 cellular response to UV-C(GO:0071494)
0.1 0.8 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 0.8 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 1.3 GO:0034465 response to carbon monoxide(GO:0034465)
0.1 0.5 GO:0016095 polyprenol catabolic process(GO:0016095)
0.1 0.9 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.8 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.5 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.5 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.7 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.1 0.3 GO:0031296 B cell costimulation(GO:0031296)
0.1 0.2 GO:0039521 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521)
0.1 0.3 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.7 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.5 GO:0070458 establishment of blood-nerve barrier(GO:0008065) cellular detoxification of nitrogen compound(GO:0070458)
0.1 0.8 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.6 GO:0071877 relaxation of vascular smooth muscle(GO:0060087) regulation of adrenergic receptor signaling pathway(GO:0071877)
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.2 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.1 2.5 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 0.5 GO:0003383 apical constriction(GO:0003383)
0.1 0.2 GO:0036269 swimming behavior(GO:0036269)
0.1 0.2 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.1 0.2 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.4 GO:0050955 thermoception(GO:0050955)
0.1 0.6 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.4 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.9 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.6 GO:0032596 protein transport into membrane raft(GO:0032596)
0.0 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.7 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.3 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.2 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.2 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.4 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.2 GO:1901545 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.0 0.2 GO:0035668 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 3.2 GO:0070206 protein trimerization(GO:0070206)
0.0 0.6 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 1.0 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.5 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.2 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.2 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.5 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 1.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 1.2 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.4 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.4 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.4 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.3 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.6 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 1.2 GO:0006953 acute-phase response(GO:0006953)
0.0 0.1 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 0.2 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0038042 dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.2 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.2 GO:0035898 parathyroid hormone secretion(GO:0035898) post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.0 0.4 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.6 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.3 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.4 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.5 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 0.8 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.5 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.7 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.1 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.3 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0006527 arginine catabolic process(GO:0006527)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.5 GO:0097179 protease inhibitor complex(GO:0097179)
0.2 1.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.6 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 4.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.5 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.9 GO:0000243 commitment complex(GO:0000243)
0.1 0.4 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 1.0 GO:0032982 myosin filament(GO:0032982)
0.0 0.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 3.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.5 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.2 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.1 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.3 GO:0055037 recycling endosome(GO:0055037)
0.0 0.5 GO:0036020 endolysosome membrane(GO:0036020)
0.0 1.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.4 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.1 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.5 GO:0009986 cell surface(GO:0009986)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.3 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.2 1.4 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.2 0.6 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.2 0.6 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 0.8 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.2 3.5 GO:0050700 CARD domain binding(GO:0050700)
0.2 0.8 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 1.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.4 GO:1902271 D3 vitamins binding(GO:1902271)
0.1 0.5 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 0.4 GO:0016297 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.1 0.3 GO:0000035 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.1 0.8 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 1.2 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.4 GO:0008431 vitamin E binding(GO:0008431)
0.1 1.4 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.3 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 4.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.8 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.2 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 1.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.2 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.1 0.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.4 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.3 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1 0.2 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.2 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0042806 fucose binding(GO:0042806)
0.0 0.9 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.6 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.2 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.5 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 1.3 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.4 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 1.2 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.5 GO:0043295 glutathione binding(GO:0043295)
0.0 0.2 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.4 GO:0031432 titin binding(GO:0031432)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.7 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 1.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.5 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.3 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.4 GO:0032813 death receptor binding(GO:0005123) tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.9 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.6 PID GLYPICAN 1PATHWAY Glypican 1 network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 0.8 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 5.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 0.8 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 3.9 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs