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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for EN1_ESX1_GBX1

Z-value: 0.42

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Transcription factors associated with EN1_ESX1_GBX1

Gene Symbol Gene ID Gene Info
EN1
ENSG00000163064.6 engrailed homeobox 1
ESX1
ENSG00000123576.5 ESX homeobox 1
GBX1
ENSG00000164900.4 gastrulation brain homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EN1hg19_v2_chr2_-_119605253_1196052640.693.1e-01Click!
GBX1hg19_v2_chr7_-_150864635_150864785-0.435.7e-01Click!

Activity profile of EN1_ESX1_GBX1 motif

Sorted Z-values of EN1_ESX1_GBX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_105416039 0.51 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr16_+_53133070 0.49 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr17_-_64225508 0.48 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr15_-_37393406 0.37 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr10_-_101825151 0.35 ENST00000441382.1
CPN1
carboxypeptidase N, polypeptide 1
chr10_-_93392811 0.33 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr11_+_77532233 0.29 ENST00000525409.1
AAMDC
adipogenesis associated, Mth938 domain containing
chr17_+_59489112 0.28 ENST00000335108.2
C17orf82
chromosome 17 open reading frame 82
chr6_+_43968306 0.28 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223
chromosome 6 open reading frame 223
chr3_-_112360116 0.28 ENST00000206423.3
ENST00000439685.2
CCDC80
coiled-coil domain containing 80
chr12_-_10978957 0.25 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr16_+_12059091 0.25 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr20_-_45976816 0.24 ENST00000441977.1
ZMYND8
zinc finger, MYND-type containing 8
chr2_-_73460334 0.24 ENST00000258083.2
PRADC1
protease-associated domain containing 1
chr5_+_31193847 0.24 ENST00000514738.1
ENST00000265071.2
CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr7_+_99717230 0.20 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chr14_-_104181771 0.20 ENST00000554913.1
ENST00000554974.1
ENST00000553361.1
ENST00000555055.1
ENST00000555964.1
ENST00000556682.1
ENST00000445556.1
ENST00000553332.1
ENST00000352127.7
XRCC3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr1_-_234667504 0.20 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
RP5-855F14.1
chr19_-_47137942 0.20 ENST00000300873.4
GNG8
guanine nucleotide binding protein (G protein), gamma 8
chr8_+_98881268 0.19 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
MATN2
matrilin 2
chr14_-_51027838 0.18 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr2_-_55237484 0.18 ENST00000394609.2
RTN4
reticulon 4
chr14_+_104182105 0.18 ENST00000311141.2
ZFYVE21
zinc finger, FYVE domain containing 21
chr9_-_3469181 0.18 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr19_+_45973120 0.18 ENST00000592811.1
ENST00000586615.1
FOSB
FBJ murine osteosarcoma viral oncogene homolog B
chr11_-_31531121 0.18 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr1_+_84767289 0.17 ENST00000394834.3
ENST00000370669.1
SAMD13
sterile alpha motif domain containing 13
chr6_-_26032288 0.17 ENST00000244661.2
HIST1H3B
histone cluster 1, H3b
chr8_+_98900132 0.17 ENST00000520016.1
MATN2
matrilin 2
chr7_+_138145076 0.17 ENST00000343526.4
TRIM24
tripartite motif containing 24
chr15_+_89164520 0.17 ENST00000332810.3
AEN
apoptosis enhancing nuclease
chr11_-_111794446 0.17 ENST00000527950.1
CRYAB
crystallin, alpha B
chr5_+_148737562 0.17 ENST00000274569.4
PCYOX1L
prenylcysteine oxidase 1 like
chr2_+_158114051 0.17 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chrX_-_71458802 0.16 ENST00000373657.1
ENST00000334463.3
ERCC6L
excision repair cross-complementing rodent repair deficiency, complementation group 6-like
chr13_-_67802549 0.16 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr6_+_26087509 0.16 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
HFE
hemochromatosis
chr7_+_77428066 0.15 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
PHTF2
putative homeodomain transcription factor 2
chr1_-_21625486 0.15 ENST00000481130.2
ECE1
endothelin converting enzyme 1
chr9_-_116840728 0.15 ENST00000265132.3
AMBP
alpha-1-microglobulin/bikunin precursor
chr13_-_96329048 0.15 ENST00000606011.1
ENST00000499499.2
DNAJC3-AS1
DNAJC3 antisense RNA 1 (head to head)
chr12_-_28122980 0.15 ENST00000395868.3
ENST00000534890.1
PTHLH
parathyroid hormone-like hormone
chr4_+_147096837 0.15 ENST00000296581.5
ENST00000502781.1
LSM6
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr3_+_149191723 0.14 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr16_+_69345243 0.14 ENST00000254950.11
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr19_-_52307357 0.14 ENST00000594900.1
FPR1
formyl peptide receptor 1
chr4_-_89442940 0.14 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr5_-_159827033 0.14 ENST00000523213.1
C5orf54
chromosome 5 open reading frame 54
chr11_+_77532155 0.14 ENST00000532481.1
ENST00000526415.1
ENST00000393427.2
ENST00000527134.1
ENST00000304716.8
AAMDC
adipogenesis associated, Mth938 domain containing
chr6_-_111927449 0.13 ENST00000368761.5
ENST00000392556.4
ENST00000340026.6
TRAF3IP2
TRAF3 interacting protein 2
chr9_-_5339873 0.13 ENST00000223862.1
ENST00000223858.4
RLN1
relaxin 1
chr13_+_110958124 0.13 ENST00000400163.2
COL4A2
collagen, type IV, alpha 2
chr14_-_55658323 0.13 ENST00000554067.1
ENST00000247191.2
DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr6_-_109702885 0.13 ENST00000504373.1
CD164
CD164 molecule, sialomucin
chr8_-_42698292 0.13 ENST00000529779.1
THAP1
THAP domain containing, apoptosis associated protein 1
chr19_+_50016610 0.13 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr1_+_62901968 0.13 ENST00000452143.1
ENST00000442679.1
ENST00000371146.1
USP1
ubiquitin specific peptidase 1
chr12_-_56693758 0.13 ENST00000547298.1
ENST00000551936.1
ENST00000551253.1
ENST00000551473.1
CS
citrate synthase
chr1_-_197115818 0.13 ENST00000367409.4
ENST00000294732.7
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr15_+_59910132 0.13 ENST00000559200.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr4_+_119200215 0.12 ENST00000602573.1
SNHG8
small nucleolar RNA host gene 8 (non-protein coding)
chr6_-_111927062 0.12 ENST00000359831.4
TRAF3IP2
TRAF3 interacting protein 2
chr12_+_28410128 0.12 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr3_-_178103144 0.12 ENST00000417383.1
ENST00000418585.1
ENST00000411727.1
ENST00000439810.1
RP11-33A14.1
RP11-33A14.1
chr5_+_150639360 0.12 ENST00000523004.1
GM2A
GM2 ganglioside activator
chr21_+_17909594 0.12 ENST00000441820.1
ENST00000602280.1
LINC00478
long intergenic non-protein coding RNA 478
chr5_+_136070614 0.12 ENST00000502421.1
CTB-1I21.1
CTB-1I21.1
chr1_+_117544366 0.12 ENST00000256652.4
ENST00000369470.1
CD101
CD101 molecule
chr19_+_50016411 0.12 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr11_+_34663913 0.12 ENST00000532302.1
EHF
ets homologous factor
chr15_-_72565340 0.12 ENST00000568360.1
PARP6
poly (ADP-ribose) polymerase family, member 6
chr6_+_26365443 0.12 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2
butyrophilin, subfamily 3, member A2
chrX_-_100129128 0.12 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
NOX1
NADPH oxidase 1
chr14_+_104182061 0.12 ENST00000216602.6
ZFYVE21
zinc finger, FYVE domain containing 21
chr17_-_57229155 0.12 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr14_+_74551650 0.11 ENST00000554938.1
LIN52
lin-52 homolog (C. elegans)
chr1_-_151762900 0.11 ENST00000440583.2
TDRKH
tudor and KH domain containing
chr12_-_88974236 0.11 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG
KIT ligand
chr18_+_46065393 0.11 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr8_+_22424551 0.11 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr15_-_64673630 0.11 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
KIAA0101
chr11_-_71823266 0.11 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
ANAPC15
anaphase promoting complex subunit 15
chr5_+_115177178 0.11 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chrX_+_77166172 0.11 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr16_+_53412368 0.11 ENST00000565189.1
RP11-44F14.2
RP11-44F14.2
chr12_+_7013897 0.11 ENST00000007969.8
ENST00000323702.5
LRRC23
leucine rich repeat containing 23
chr7_+_77428149 0.11 ENST00000415251.2
ENST00000275575.7
PHTF2
putative homeodomain transcription factor 2
chr15_+_58702742 0.11 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chr9_+_2159850 0.11 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_+_28261492 0.11 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr8_-_102803163 0.10 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD
neurocalcin delta
chr14_+_32798547 0.10 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr9_-_112970436 0.10 ENST00000400613.4
C9orf152
chromosome 9 open reading frame 152
chr7_-_72971934 0.10 ENST00000411832.1
BCL7B
B-cell CLL/lymphoma 7B
chr1_+_196912902 0.10 ENST00000476712.2
ENST00000367415.5
CFHR2
complement factor H-related 2
chr2_+_113299990 0.10 ENST00000537335.1
ENST00000417433.2
POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chr9_-_5304432 0.10 ENST00000416837.1
ENST00000308420.3
RLN2
relaxin 2
chr1_+_28261533 0.10 ENST00000411604.1
ENST00000373888.4
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr8_+_27238147 0.10 ENST00000412793.1
PTK2B
protein tyrosine kinase 2 beta
chr12_-_28123206 0.10 ENST00000542963.1
ENST00000535992.1
PTHLH
parathyroid hormone-like hormone
chr15_-_64673665 0.10 ENST00000300035.4
KIAA0101
KIAA0101
chr14_-_23426270 0.10 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS4
HAUS augmin-like complex, subunit 4
chr14_+_39944025 0.10 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
RP11-111A21.1
chr12_-_56694083 0.10 ENST00000552688.1
ENST00000548041.1
ENST00000551137.1
ENST00000551968.1
ENST00000542324.2
ENST00000546930.1
ENST00000549221.1
ENST00000550159.1
ENST00000550734.1
CS
citrate synthase
chr5_+_137673200 0.10 ENST00000434981.2
FAM53C
family with sequence similarity 53, member C
chr14_-_55658252 0.10 ENST00000395425.2
DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr20_-_50722183 0.10 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr1_-_211848899 0.10 ENST00000366998.3
ENST00000540251.1
ENST00000366999.4
NEK2
NIMA-related kinase 2
chr5_+_172068232 0.09 ENST00000520919.1
ENST00000522853.1
ENST00000369800.5
NEURL1B
neuralized E3 ubiquitin protein ligase 1B
chr20_-_50418972 0.09 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr10_+_94451574 0.09 ENST00000492654.2
HHEX
hematopoietically expressed homeobox
chr13_-_36788718 0.09 ENST00000317764.6
ENST00000379881.3
SOHLH2
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr9_-_77643307 0.09 ENST00000376834.3
ENST00000376830.3
C9orf41
chromosome 9 open reading frame 41
chr16_+_103816 0.09 ENST00000383018.3
ENST00000417493.1
SNRNP25
small nuclear ribonucleoprotein 25kDa (U11/U12)
chr14_-_38064198 0.09 ENST00000250448.2
FOXA1
forkhead box A1
chr1_+_28261621 0.09 ENST00000549094.1
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr8_+_107738240 0.09 ENST00000449762.2
ENST00000297447.6
OXR1
oxidation resistance 1
chr17_+_43238438 0.09 ENST00000593138.1
ENST00000586681.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr6_-_32908792 0.09 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr11_+_115498761 0.09 ENST00000424313.2
AP000997.1
AP000997.1
chrX_-_100129320 0.09 ENST00000372966.3
NOX1
NADPH oxidase 1
chr1_-_201140673 0.09 ENST00000367333.2
TMEM9
transmembrane protein 9
chr12_+_56473939 0.09 ENST00000450146.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chrX_+_72783026 0.09 ENST00000373504.6
ENST00000373502.5
CHIC1
cysteine-rich hydrophobic domain 1
chr4_+_119199904 0.09 ENST00000602483.1
ENST00000602819.1
SNHG8
small nucleolar RNA host gene 8 (non-protein coding)
chr13_-_46679144 0.09 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr3_+_151591422 0.09 ENST00000362032.5
SUCNR1
succinate receptor 1
chr12_+_56473910 0.09 ENST00000411731.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr5_+_162864575 0.09 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
CCNG1
cyclin G1
chr5_+_52776228 0.09 ENST00000256759.3
FST
follistatin
chr14_-_83262540 0.09 ENST00000554451.1
RP11-11K13.1
RP11-11K13.1
chr1_-_36916011 0.09 ENST00000356637.5
ENST00000354267.3
ENST00000235532.5
OSCP1
organic solute carrier partner 1
chr14_-_23426322 0.08 ENST00000555367.1
HAUS4
HAUS augmin-like complex, subunit 4
chr8_+_41386725 0.08 ENST00000276533.3
ENST00000520710.1
ENST00000518671.1
GINS4
GINS complex subunit 4 (Sld5 homolog)
chr4_+_3388057 0.08 ENST00000538395.1
RGS12
regulator of G-protein signaling 12
chr12_-_56694142 0.08 ENST00000550655.1
ENST00000548567.1
ENST00000551430.2
ENST00000351328.3
CS
citrate synthase
chr4_+_174089904 0.08 ENST00000265000.4
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr2_-_224467093 0.08 ENST00000305409.2
SCG2
secretogranin II
chr17_+_47448102 0.08 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr4_+_25915896 0.08 ENST00000514384.1
SMIM20
small integral membrane protein 20
chr14_-_23426337 0.08 ENST00000342454.8
ENST00000555986.1
ENST00000541587.1
ENST00000554516.1
ENST00000347758.2
ENST00000206474.7
ENST00000555040.1
HAUS4
HAUS augmin-like complex, subunit 4
chr7_-_130080977 0.08 ENST00000223208.5
CEP41
centrosomal protein 41kDa
chr14_+_74815116 0.08 ENST00000256362.4
VRTN
vertebrae development associated
chr10_+_5005598 0.08 ENST00000442997.1
AKR1C1
aldo-keto reductase family 1, member C1
chr1_+_43291220 0.08 ENST00000372514.3
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr12_+_107712173 0.08 ENST00000280758.5
ENST00000420571.2
BTBD11
BTB (POZ) domain containing 11
chr1_+_207277590 0.08 ENST00000367070.3
C4BPA
complement component 4 binding protein, alpha
chr11_-_117748138 0.08 ENST00000527717.1
FXYD6
FXYD domain containing ion transport regulator 6
chr10_-_33405600 0.08 ENST00000414308.1
RP11-342D11.3
RP11-342D11.3
chr1_+_62439037 0.08 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr5_+_81601166 0.08 ENST00000439350.1
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr22_+_42834029 0.08 ENST00000428765.1
CTA-126B4.7
CTA-126B4.7
chr11_+_34664014 0.08 ENST00000527935.1
EHF
ets homologous factor
chr20_+_43990576 0.08 ENST00000372727.1
ENST00000414310.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr18_+_32556892 0.08 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr9_+_116225999 0.08 ENST00000317613.6
RGS3
regulator of G-protein signaling 3
chr12_-_57328187 0.08 ENST00000293502.1
SDR9C7
short chain dehydrogenase/reductase family 9C, member 7
chr14_-_45252031 0.08 ENST00000556405.1
RP11-398E10.1
RP11-398E10.1
chr6_-_711395 0.08 ENST00000606285.1
RP11-532F6.3
RP11-532F6.3
chr12_-_121972556 0.07 ENST00000545022.1
KDM2B
lysine (K)-specific demethylase 2B
chr11_-_117747434 0.07 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD6
FXYD domain containing ion transport regulator 6
chr17_-_28661065 0.07 ENST00000328886.4
ENST00000538566.2
TMIGD1
transmembrane and immunoglobulin domain containing 1
chr9_-_136933134 0.07 ENST00000303407.7
BRD3
bromodomain containing 3
chr6_-_72130472 0.07 ENST00000426635.2
LINC00472
long intergenic non-protein coding RNA 472
chr16_+_58283814 0.07 ENST00000443128.2
ENST00000219299.4
CCDC113
coiled-coil domain containing 113
chr4_-_19458597 0.07 ENST00000505347.1
RP11-3J1.1
RP11-3J1.1
chr1_-_21620877 0.07 ENST00000527991.1
ECE1
endothelin converting enzyme 1
chr13_+_78315295 0.07 ENST00000351546.3
SLAIN1
SLAIN motif family, member 1
chr3_+_130569429 0.07 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr5_+_142286887 0.07 ENST00000451259.1
ARHGAP26
Rho GTPase activating protein 26
chr2_+_38152462 0.07 ENST00000354545.2
RMDN2
regulator of microtubule dynamics 2
chr12_+_52056548 0.07 ENST00000545061.1
ENST00000355133.3
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr4_+_66536248 0.07 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1
RP11-807H7.1
chr3_+_167453493 0.07 ENST00000295777.5
ENST00000472747.2
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr17_+_18086392 0.07 ENST00000541285.1
ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr15_-_65903407 0.07 ENST00000395644.4
ENST00000567744.1
ENST00000568573.1
ENST00000562830.1
ENST00000569491.1
ENST00000561769.1
VWA9
von Willebrand factor A domain containing 9
chr11_-_71823796 0.07 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
ANAPC15
anaphase promoting complex subunit 15
chr1_+_153746683 0.07 ENST00000271857.2
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr14_-_23426231 0.07 ENST00000556915.1
HAUS4
HAUS augmin-like complex, subunit 4
chr4_-_46911223 0.07 ENST00000396533.1
COX7B2
cytochrome c oxidase subunit VIIb2
chr2_+_128293323 0.07 ENST00000389524.4
ENST00000428314.1
MYO7B
myosin VIIB
chr10_+_135050908 0.07 ENST00000325980.9
VENTX
VENT homeobox
chr16_-_46655538 0.07 ENST00000303383.3
SHCBP1
SHC SH2-domain binding protein 1
chr2_-_220117867 0.07 ENST00000456818.1
ENST00000447205.1
TUBA4A
tubulin, alpha 4a
chr3_-_180397256 0.07 ENST00000442201.2
CCDC39
coiled-coil domain containing 39
chr1_+_196788887 0.07 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
CFHR1
CFHR2
complement factor H-related 1
complement factor H-related 2
chr1_+_236958554 0.07 ENST00000366577.5
ENST00000418145.2
MTR
5-methyltetrahydrofolate-homocysteine methyltransferase
chr15_+_89164560 0.06 ENST00000379231.3
ENST00000559528.1
AEN
apoptosis enhancing nuclease
chr9_-_75653627 0.06 ENST00000446946.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr7_+_127292234 0.06 ENST00000354725.3
SND1
staphylococcal nuclease and tudor domain containing 1
chr5_+_52776449 0.06 ENST00000396947.3
FST
follistatin
chr17_+_36508826 0.06 ENST00000580660.1
SOCS7
suppressor of cytokine signaling 7
chr7_-_55620433 0.06 ENST00000418904.1
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr13_-_46679185 0.06 ENST00000439329.3
CPB2
carboxypeptidase B2 (plasma)
chr6_-_32908765 0.06 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr15_+_75080883 0.06 ENST00000567571.1
CSK
c-src tyrosine kinase
chrX_+_154444643 0.06 ENST00000286428.5
VBP1
von Hippel-Lindau binding protein 1
chr12_-_118628350 0.06 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr15_+_69857515 0.06 ENST00000559477.1
RP11-279F6.1
RP11-279F6.1
chr4_+_129732419 0.06 ENST00000510308.1
PHF17
jade family PHD finger 1

Network of associatons between targets according to the STRING database.

First level regulatory network of EN1_ESX1_GBX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030070 insulin processing(GO:0030070)
0.1 0.2 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 0.5 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.2 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.1 0.2 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.1 0.3 GO:0034756 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759)
0.1 0.2 GO:2001190 peptide antigen assembly with MHC class II protein complex(GO:0002503) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 0.2 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.6 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0 0.2 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.2 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.1 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.0 0.1 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.0 0.2 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.0 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.1 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:2000537 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.1 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.0 0.0 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.0 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.1 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.1 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.2 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.0 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.0 GO:1900175 regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175)
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.1 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.0 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.0 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.0 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.0 GO:0051866 general adaptation syndrome(GO:0051866)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.2 GO:0071547 piP-body(GO:0071547)
0.0 0.2 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.0 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.3 GO:0004108 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.1 0.3 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.1 0.4 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.2 GO:0019862 IgA binding(GO:0019862)
0.0 0.1 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.0 0.1 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.0 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.2 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.0 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0047718 androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.0 0.0 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.0 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.0 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.0 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)