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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for ESR1

Z-value: 0.52

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Transcription factors associated with ESR1

Gene Symbol Gene ID Gene Info
ESR1
ENSG00000091831.17 estrogen receptor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ESR1hg19_v2_chr6_+_152130240_152130274-0.366.4e-01Click!

Activity profile of ESR1 motif

Sorted Z-values of ESR1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_-_47352477 0.24 ENST00000593412.1
PRED62
Uncharacterized protein
chr8_-_144674284 0.20 ENST00000528519.1
EEF1D
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr16_+_28857916 0.19 ENST00000563591.1
SH2B1
SH2B adaptor protein 1
chrX_-_21776281 0.17 ENST00000379494.3
SMPX
small muscle protein, X-linked
chr19_+_19516561 0.17 ENST00000457895.2
GATAD2A
GATA zinc finger domain containing 2A
chr1_-_38157877 0.17 ENST00000477060.1
ENST00000491981.1
ENST00000488137.1
C1orf109
chromosome 1 open reading frame 109
chr2_-_74779744 0.17 ENST00000409249.1
LOXL3
lysyl oxidase-like 3
chr11_-_9482010 0.17 ENST00000596206.1
AC132192.1
LOC644656 protein; Uncharacterized protein
chr22_+_44427230 0.16 ENST00000444029.1
PARVB
parvin, beta
chr11_+_62439126 0.15 ENST00000377953.3
C11orf83
chromosome 11 open reading frame 83
chr6_+_35265586 0.14 ENST00000542066.1
ENST00000316637.5
DEF6
differentially expressed in FDCP 6 homolog (mouse)
chr8_-_103136481 0.14 ENST00000524209.1
ENST00000517822.1
ENST00000523923.1
ENST00000521599.1
ENST00000521964.1
ENST00000311028.3
ENST00000518166.1
NCALD
neurocalcin delta
chr22_+_22723969 0.14 ENST00000390295.2
IGLV7-46
immunoglobulin lambda variable 7-46 (gene/pseudogene)
chr2_+_242750274 0.13 ENST00000405370.1
NEU4
sialidase 4
chr2_+_131328402 0.13 ENST00000409793.1
ENST00000409982.1
AC140481.2
Uncharacterized protein
chr16_-_51185149 0.13 ENST00000566102.1
ENST00000541611.1
SALL1
spalt-like transcription factor 1
chr12_-_124457163 0.13 ENST00000535556.1
CCDC92
coiled-coil domain containing 92
chr9_-_21368075 0.12 ENST00000449498.1
IFNA13
interferon, alpha 13
chr19_-_10613421 0.12 ENST00000393623.2
KEAP1
kelch-like ECH-associated protein 1
chr16_-_88772670 0.12 ENST00000562544.1
RNF166
ring finger protein 166
chr1_-_111970353 0.12 ENST00000369732.3
OVGP1
oviductal glycoprotein 1, 120kDa
chr7_+_140396946 0.11 ENST00000476470.1
ENST00000471136.1
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr22_+_22676808 0.11 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr22_-_32034376 0.11 ENST00000431201.1
PISD
phosphatidylserine decarboxylase
chr17_+_65027509 0.11 ENST00000375684.1
AC005544.1
Uncharacterized protein
chr4_+_89300158 0.10 ENST00000502870.1
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr20_+_48429233 0.10 ENST00000417961.1
SLC9A8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr14_+_103995546 0.10 ENST00000299202.4
TRMT61A
tRNA methyltransferase 61 homolog A (S. cerevisiae)
chr22_+_24199113 0.10 ENST00000405847.1
SLC2A11
solute carrier family 2 (facilitated glucose transporter), member 11
chr15_+_75335604 0.10 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr8_+_144640499 0.10 ENST00000525721.1
ENST00000534018.1
GSDMD
gasdermin D
chr16_-_19725899 0.10 ENST00000567367.1
KNOP1
lysine-rich nucleolar protein 1
chr22_-_32034409 0.10 ENST00000429683.1
PISD
phosphatidylserine decarboxylase
chr5_+_32710736 0.10 ENST00000415685.2
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr11_-_86383650 0.10 ENST00000526944.1
ENST00000530335.1
ENST00000543262.1
ENST00000524826.1
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr2_+_27719697 0.10 ENST00000264717.2
ENST00000424318.2
GCKR
glucokinase (hexokinase 4) regulator
chr19_-_11639910 0.10 ENST00000588998.1
ENST00000586149.1
ECSIT
ECSIT signalling integrator
chr4_-_89079817 0.09 ENST00000505480.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr12_+_123874589 0.09 ENST00000437502.1
SETD8
SET domain containing (lysine methyltransferase) 8
chr7_+_140396756 0.09 ENST00000460088.1
ENST00000472695.1
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr12_+_100967420 0.09 ENST00000266754.5
ENST00000547754.1
GAS2L3
growth arrest-specific 2 like 3
chr5_+_154135453 0.09 ENST00000517616.1
ENST00000518892.1
LARP1
La ribonucleoprotein domain family, member 1
chr7_-_99569468 0.09 ENST00000419575.1
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr14_+_52780998 0.09 ENST00000557436.1
PTGER2
prostaglandin E receptor 2 (subtype EP2), 53kDa
chr1_+_55446465 0.09 ENST00000371268.3
TMEM61
transmembrane protein 61
chr14_-_23791484 0.09 ENST00000594872.1
AL049829.1
Uncharacterized protein
chr20_+_42295745 0.09 ENST00000396863.4
ENST00000217026.4
MYBL2
v-myb avian myeloblastosis viral oncogene homolog-like 2
chr20_+_49411523 0.09 ENST00000371608.2
BCAS4
breast carcinoma amplified sequence 4
chr8_-_123793048 0.09 ENST00000607710.1
RP11-44N11.2
RP11-44N11.2
chr19_-_10445399 0.09 ENST00000592945.1
ICAM3
intercellular adhesion molecule 3
chr16_+_28857957 0.09 ENST00000567536.1
SH2B1
SH2B adaptor protein 1
chr7_+_79763271 0.09 ENST00000442586.1
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr11_+_134146635 0.09 ENST00000431683.2
GLB1L3
galactosidase, beta 1-like 3
chr19_+_1261106 0.09 ENST00000588411.1
CIRBP
cold inducible RNA binding protein
chr19_-_13068012 0.08 ENST00000316939.1
GADD45GIP1
growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr1_-_16763685 0.08 ENST00000540400.1
SPATA21
spermatogenesis associated 21
chr17_-_39677971 0.08 ENST00000393976.2
KRT15
keratin 15
chr19_-_11639931 0.08 ENST00000592312.1
ENST00000590480.1
ENST00000585318.1
ENST00000252440.7
ENST00000417981.2
ENST00000270517.7
ECSIT
ECSIT signalling integrator
chr6_+_41196052 0.08 ENST00000341495.2
TREML4
triggering receptor expressed on myeloid cells-like 4
chr3_-_52488048 0.08 ENST00000232975.3
TNNC1
troponin C type 1 (slow)
chr19_-_59010565 0.08 ENST00000594786.1
SLC27A5
solute carrier family 27 (fatty acid transporter), member 5
chr11_+_8704748 0.08 ENST00000526562.1
ENST00000525981.1
RPL27A
ribosomal protein L27a
chr8_+_144640477 0.08 ENST00000262580.4
GSDMD
gasdermin D
chr22_+_30821732 0.08 ENST00000355143.4
MTFP1
mitochondrial fission process 1
chr2_+_233243233 0.08 ENST00000392027.2
ALPP
alkaline phosphatase, placental
chr11_+_47270475 0.08 ENST00000481889.2
ENST00000436778.1
ENST00000531660.1
ENST00000407404.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr14_+_103995503 0.08 ENST00000389749.4
TRMT61A
tRNA methyltransferase 61 homolog A (S. cerevisiae)
chr11_-_62439012 0.08 ENST00000532208.1
ENST00000377954.2
ENST00000415855.2
ENST00000431002.2
ENST00000354588.3
C11orf48
chromosome 11 open reading frame 48
chr8_-_100905363 0.08 ENST00000524245.1
COX6C
cytochrome c oxidase subunit VIc
chrX_-_106959631 0.08 ENST00000486554.1
ENST00000372390.4
TSC22D3
TSC22 domain family, member 3
chr19_-_51869592 0.08 ENST00000596253.1
ENST00000309244.4
ETFB
electron-transfer-flavoprotein, beta polypeptide
chr19_-_36001386 0.08 ENST00000461300.1
DMKN
dermokine
chr7_+_149535455 0.08 ENST00000223210.4
ENST00000460379.1
ZNF862
zinc finger protein 862
chr19_+_58790314 0.08 ENST00000196548.5
ENST00000608843.1
ZNF8
ZNF8
Zinc finger protein 8
zinc finger protein 8
chr11_-_86383370 0.08 ENST00000526834.1
ENST00000359636.2
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr19_-_49567124 0.07 ENST00000301411.3
NTF4
neurotrophin 4
chr4_+_128982490 0.07 ENST00000394288.3
ENST00000432347.2
ENST00000264584.5
ENST00000441387.1
ENST00000427266.1
ENST00000354456.3
LARP1B
La ribonucleoprotein domain family, member 1B
chr3_-_47554791 0.07 ENST00000449409.1
ENST00000414236.1
ENST00000444760.1
ENST00000439305.1
ELP6
elongator acetyltransferase complex subunit 6
chrX_+_153770421 0.07 ENST00000369609.5
ENST00000369607.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr17_+_73629500 0.07 ENST00000375215.3
SMIM5
small integral membrane protein 5
chr19_+_8740061 0.07 ENST00000593792.1
CTD-2586B10.1
CTD-2586B10.1
chr1_-_20306909 0.07 ENST00000375111.3
ENST00000400520.3
PLA2G2A
phospholipase A2, group IIA (platelets, synovial fluid)
chr10_+_134210672 0.07 ENST00000305233.5
ENST00000368609.4
PWWP2B
PWWP domain containing 2B
chr17_-_73285293 0.07 ENST00000582778.1
ENST00000581988.1
ENST00000579207.1
ENST00000583332.1
ENST00000416858.2
ENST00000442286.2
ENST00000580151.1
ENST00000580994.1
ENST00000584438.1
ENST00000320362.3
ENST00000580273.1
SLC25A19
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr19_-_2090131 0.07 ENST00000591326.1
MOB3A
MOB kinase activator 3A
chr8_-_144691718 0.07 ENST00000377579.3
ENST00000433751.1
ENST00000220966.6
PYCRL
pyrroline-5-carboxylate reductase-like
chr15_+_101389945 0.07 ENST00000561231.1
ENST00000559331.1
ENST00000558254.1
RP11-66B24.2
RP11-66B24.2
chr20_+_3801162 0.07 ENST00000379573.2
ENST00000379567.2
ENST00000455742.1
ENST00000246041.2
AP5S1
adaptor-related protein complex 5, sigma 1 subunit
chr9_-_127177703 0.07 ENST00000259457.3
ENST00000536392.1
ENST00000441097.1
PSMB7
proteasome (prosome, macropain) subunit, beta type, 7
chr3_+_38017264 0.07 ENST00000436654.1
CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr16_+_28858004 0.07 ENST00000322610.8
SH2B1
SH2B adaptor protein 1
chr1_+_145726886 0.07 ENST00000443667.1
PDZK1
PDZ domain containing 1
chr11_+_47270436 0.07 ENST00000395397.3
ENST00000405576.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr19_+_47840346 0.07 ENST00000600626.1
C5AR2
complement component 5a receptor 2
chr1_+_245133656 0.07 ENST00000366521.3
EFCAB2
EF-hand calcium binding domain 2
chr20_+_48429356 0.07 ENST00000361573.2
ENST00000541138.1
ENST00000539601.1
SLC9A8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr16_+_50730910 0.07 ENST00000300589.2
NOD2
nucleotide-binding oligomerization domain containing 2
chr4_-_89080362 0.07 ENST00000503830.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr19_-_29218538 0.07 ENST00000592347.1
ENST00000586528.1
AC005307.3
AC005307.3
chr19_+_7562431 0.07 ENST00000361664.2
C19orf45
chromosome 19 open reading frame 45
chr7_-_6066183 0.07 ENST00000422786.1
EIF2AK1
eukaryotic translation initiation factor 2-alpha kinase 1
chr12_+_16064258 0.07 ENST00000524480.1
ENST00000531803.1
ENST00000532964.1
DERA
deoxyribose-phosphate aldolase (putative)
chr16_-_67427389 0.06 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
TPPP3
tubulin polymerization-promoting protein family member 3
chr9_+_129987488 0.06 ENST00000446764.1
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr2_+_219264466 0.06 ENST00000273062.2
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr12_-_56123444 0.06 ENST00000546457.1
ENST00000549117.1
CD63
CD63 molecule
chrX_-_1571759 0.06 ENST00000381317.3
ENST00000416733.2
ASMTL
acetylserotonin O-methyltransferase-like
chr1_+_6684918 0.06 ENST00000054650.4
THAP3
THAP domain containing, apoptosis associated protein 3
chr1_-_21620877 0.06 ENST00000527991.1
ECE1
endothelin converting enzyme 1
chr3_+_15469058 0.06 ENST00000432764.2
EAF1
ELL associated factor 1
chr1_+_52521928 0.06 ENST00000489308.2
BTF3L4
basic transcription factor 3-like 4
chr1_+_44444865 0.06 ENST00000372324.1
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr1_+_1217305 0.06 ENST00000470022.1
SCNN1D
sodium channel, non-voltage-gated 1, delta subunit
chr9_-_130637244 0.06 ENST00000373156.1
AK1
adenylate kinase 1
chr1_+_245133606 0.06 ENST00000447569.2
EFCAB2
EF-hand calcium binding domain 2
chr8_-_100905850 0.06 ENST00000520271.1
ENST00000522940.1
ENST00000523016.1
ENST00000517682.2
ENST00000297564.2
COX6C
cytochrome c oxidase subunit VIc
chr16_+_50308028 0.06 ENST00000566761.2
ADCY7
adenylate cyclase 7
chr4_-_155511887 0.06 ENST00000302053.3
ENST00000403106.3
FGA
fibrinogen alpha chain
chr5_+_149109825 0.06 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr19_-_14586125 0.06 ENST00000292513.3
PTGER1
prostaglandin E receptor 1 (subtype EP1), 42kDa
chr1_-_167906020 0.06 ENST00000458574.1
MPC2
mitochondrial pyruvate carrier 2
chr15_+_91418918 0.06 ENST00000560824.1
FURIN
furin (paired basic amino acid cleaving enzyme)
chr11_+_844406 0.06 ENST00000397404.1
TSPAN4
tetraspanin 4
chr19_+_7985198 0.06 ENST00000221573.6
ENST00000595637.1
SNAPC2
small nuclear RNA activating complex, polypeptide 2, 45kDa
chr1_+_19923454 0.06 ENST00000602662.1
ENST00000602293.1
ENST00000322753.6
MINOS1-NBL1
MINOS1
MINOS1-NBL1 readthrough
mitochondrial inner membrane organizing system 1
chr5_-_139726181 0.06 ENST00000507104.1
ENST00000230990.6
HBEGF
heparin-binding EGF-like growth factor
chr14_-_100841794 0.06 ENST00000556295.1
ENST00000554820.1
WARS
tryptophanyl-tRNA synthetase
chr17_-_26989136 0.06 ENST00000247020.4
SDF2
stromal cell-derived factor 2
chr3_-_15106747 0.06 ENST00000449354.2
ENST00000444840.2
ENST00000253686.2
MRPS25
mitochondrial ribosomal protein S25
chr19_-_13213954 0.06 ENST00000590974.1
LYL1
lymphoblastic leukemia derived sequence 1
chr19_+_1908013 0.06 ENST00000454697.1
ADAT3
adenosine deaminase, tRNA-specific 3
chr8_-_41522779 0.06 ENST00000522231.1
ENST00000314214.8
ENST00000348036.4
ENST00000457297.1
ENST00000522543.1
ANK1
ankyrin 1, erythrocytic
chr22_+_41258250 0.06 ENST00000544094.1
XPNPEP3
X-prolyl aminopeptidase (aminopeptidase P) 3, putative
chr10_+_112257596 0.06 ENST00000369583.3
DUSP5
dual specificity phosphatase 5
chr3_-_176914963 0.06 ENST00000450267.1
ENST00000431674.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr19_+_56111680 0.06 ENST00000301073.3
ZNF524
zinc finger protein 524
chr12_-_31158902 0.06 ENST00000544329.1
ENST00000418254.2
ENST00000222396.5
RP11-551L14.4
RP11-551L14.4
chr19_-_10614386 0.06 ENST00000171111.5
KEAP1
kelch-like ECH-associated protein 1
chr1_+_245133278 0.06 ENST00000366522.2
EFCAB2
EF-hand calcium binding domain 2
chr12_-_120806960 0.05 ENST00000257552.2
MSI1
musashi RNA-binding protein 1
chr1_+_203097407 0.05 ENST00000367235.1
ADORA1
adenosine A1 receptor
chr9_-_120177342 0.05 ENST00000361209.2
ASTN2
astrotactin 2
chr2_-_74776586 0.05 ENST00000420535.1
LOXL3
lysyl oxidase-like 3
chr11_-_1780261 0.05 ENST00000427721.1
RP11-295K3.1
RP11-295K3.1
chr4_+_25915896 0.05 ENST00000514384.1
SMIM20
small integral membrane protein 20
chr11_+_1295809 0.05 ENST00000598274.1
AC136297.1
Uncharacterized protein
chr9_+_101984577 0.05 ENST00000223641.4
SEC61B
Sec61 beta subunit
chr3_+_37903432 0.05 ENST00000443503.2
CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr16_+_75182376 0.05 ENST00000570010.1
ENST00000568079.1
ENST00000464850.1
ENST00000332307.4
ENST00000393430.2
ZFP1
ZFP1 zinc finger protein
chr8_+_40018977 0.05 ENST00000520487.1
RP11-470M17.2
RP11-470M17.2
chr17_-_40346477 0.05 ENST00000593209.1
ENST00000587427.1
ENST00000588352.1
ENST00000414034.3
ENST00000590249.1
GHDC
GH3 domain containing
chr17_-_27507377 0.05 ENST00000531253.1
MYO18A
myosin XVIIIA
chr16_+_89686991 0.05 ENST00000393092.3
DPEP1
dipeptidase 1 (renal)
chr9_-_95896550 0.05 ENST00000375446.4
NINJ1
ninjurin 1
chr15_-_76603727 0.05 ENST00000560595.1
ENST00000433983.2
ENST00000559386.1
ENST00000559602.1
ENST00000560726.1
ENST00000557943.1
ETFA
electron-transfer-flavoprotein, alpha polypeptide
chr10_+_131265443 0.05 ENST00000306010.7
MGMT
O-6-methylguanine-DNA methyltransferase
chr16_+_29690358 0.05 ENST00000395384.4
ENST00000562473.1
QPRT
quinolinate phosphoribosyltransferase
chr1_+_38259459 0.05 ENST00000373045.6
MANEAL
mannosidase, endo-alpha-like
chr17_-_27507395 0.05 ENST00000354329.4
ENST00000527372.1
MYO18A
myosin XVIIIA
chr11_+_2397418 0.05 ENST00000530648.1
CD81
CD81 molecule
chr16_-_2581409 0.05 ENST00000567119.1
ENST00000565480.1
ENST00000382350.1
CEMP1
cementum protein 1
chr16_+_2079637 0.05 ENST00000561844.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr5_-_175395283 0.05 ENST00000513482.1
ENST00000265097.4
THOC3
THO complex 3
chr17_-_73840774 0.05 ENST00000207549.4
UNC13D
unc-13 homolog D (C. elegans)
chr4_-_89080003 0.05 ENST00000237612.3
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr22_+_39853258 0.05 ENST00000341184.6
MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr2_+_183982255 0.05 ENST00000455063.1
NUP35
nucleoporin 35kDa
chr17_+_55173933 0.05 ENST00000539273.1
AKAP1
A kinase (PRKA) anchor protein 1
chr7_-_1609591 0.05 ENST00000288607.2
ENST00000404674.3
PSMG3
proteasome (prosome, macropain) assembly chaperone 3
chr8_-_101571964 0.05 ENST00000520552.1
ENST00000521345.1
ENST00000523000.1
ENST00000335659.3
ENST00000358990.3
ENST00000519597.1
ANKRD46
ankyrin repeat domain 46
chr17_-_79869340 0.05 ENST00000538936.2
PCYT2
phosphate cytidylyltransferase 2, ethanolamine
chr22_-_21579843 0.05 ENST00000405188.4
GGT2
gamma-glutamyltransferase 2
chr11_-_503521 0.05 ENST00000534797.1
RNH1
ribonuclease/angiogenin inhibitor 1
chr16_+_88772866 0.05 ENST00000453996.2
ENST00000312060.5
ENST00000378384.3
ENST00000567949.1
ENST00000564921.1
CTU2
cytosolic thiouridylase subunit 2 homolog (S. pombe)
chr6_-_44225231 0.05 ENST00000538577.1
ENST00000537814.1
ENST00000393810.1
ENST00000393812.3
SLC35B2
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
chr1_+_179851999 0.05 ENST00000527391.1
TOR1AIP1
torsin A interacting protein 1
chr20_+_56964169 0.05 ENST00000475243.1
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chrX_+_55101495 0.05 ENST00000374974.3
ENST00000374971.1
PAGE2B
P antigen family, member 2B
chr7_+_6071007 0.05 ENST00000409061.1
ANKRD61
ankyrin repeat domain 61
chr7_+_140396465 0.05 ENST00000476279.1
ENST00000247866.4
ENST00000461457.1
ENST00000465506.1
ENST00000204307.5
ENST00000464566.1
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr18_+_33552667 0.05 ENST00000333234.5
C18orf21
chromosome 18 open reading frame 21
chr1_+_246729724 0.05 ENST00000366513.4
ENST00000366512.3
CNST
consortin, connexin sorting protein
chr20_+_44441626 0.05 ENST00000372568.4
UBE2C
ubiquitin-conjugating enzyme E2C
chr19_-_18995029 0.05 ENST00000596048.1
CERS1
ceramide synthase 1
chr19_+_39936267 0.05 ENST00000359191.6
SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr17_+_6347729 0.05 ENST00000572447.1
FAM64A
family with sequence similarity 64, member A
chr17_+_27052892 0.05 ENST00000579671.1
ENST00000579060.1
NEK8
NIMA-related kinase 8
chr20_+_32581738 0.05 ENST00000333552.5
RALY
RALY heterogeneous nuclear ribonucleoprotein
chr19_+_39574945 0.05 ENST00000331256.5
PAPL
Iron/zinc purple acid phosphatase-like protein
chr11_+_111750206 0.05 ENST00000530214.1
ENST00000530799.1
C11orf1
chromosome 11 open reading frame 1
chr19_+_39936186 0.05 ENST00000432763.2
ENST00000402194.2
ENST00000601515.1
SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr11_-_75062829 0.05 ENST00000393505.4
ARRB1
arrestin, beta 1
chr6_+_33168637 0.05 ENST00000374677.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr11_+_844067 0.05 ENST00000397406.1
ENST00000409543.2
ENST00000525201.1
TSPAN4
tetraspanin 4
chr1_-_36916011 0.05 ENST00000356637.5
ENST00000354267.3
ENST00000235532.5
OSCP1
organic solute carrier partner 1
chr16_-_28621298 0.05 ENST00000566189.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr14_+_77790901 0.05 ENST00000553586.1
ENST00000555583.1
GSTZ1
glutathione S-transferase zeta 1
chr16_+_718147 0.05 ENST00000561929.1
RHOT2
ras homolog family member T2
chr9_-_35619539 0.05 ENST00000396757.1
CD72
CD72 molecule
chr11_+_64008525 0.05 ENST00000449942.2
FKBP2
FK506 binding protein 2, 13kDa

Network of associatons between targets according to the STRING database.

First level regulatory network of ESR1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:2000329 peptidyl-lysine oxidation(GO:0018057) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.1 GO:2000360 negative regulation of fertilization(GO:0060467) negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0 0.1 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.0 0.1 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.1 GO:0010160 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.0 0.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.1 GO:0032900 negative regulation of neurotrophin production(GO:0032900)
0.0 0.1 GO:0060584 activation of MAPK activity involved in innate immune response(GO:0035419) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.1 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.0 0.1 GO:0038178 complement component C5a signaling pathway(GO:0038178) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 0.2 GO:0070269 pyroptosis(GO:0070269)
0.0 0.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 0.0 GO:1902559 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.0 0.2 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.0 GO:0072720 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.2 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.0 GO:1902824 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.0 GO:1903452 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.0 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.1 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.0 GO:0070894 transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
0.0 0.1 GO:0002432 granuloma formation(GO:0002432)
0.0 0.0 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.0 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.0 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.1 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:1901091 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.0 0.0 GO:0070845 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.1 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.2 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0032044 DSIF complex(GO:0032044)
0.0 0.0 GO:0043227 membrane-bounded organelle(GO:0043227)
0.0 0.0 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.0 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.2 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.0 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.0 GO:0001534 radial spoke(GO:0001534)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.0 0.1 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.0 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.1 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.0 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.0 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.1 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.1 GO:0005124 scavenger receptor binding(GO:0005124)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.0 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.0 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.0 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.0 0.0 GO:0047291 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism