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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for GFI1

Z-value: 0.54

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Transcription factors associated with GFI1

Gene Symbol Gene ID Gene Info
GFI1
ENSG00000162676.7 growth factor independent 1 transcriptional repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GFI1hg19_v2_chr1_-_92949505_92949543-0.534.7e-01Click!

Activity profile of GFI1 motif

Sorted Z-values of GFI1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_119056178 0.38 ENST00000525131.1
ENST00000531114.1
ENST00000355547.5
ENST00000322712.4
PDZD3
PDZ domain containing 3
chr2_-_61389240 0.37 ENST00000606876.1
RP11-493E12.1
RP11-493E12.1
chr4_-_155533787 0.34 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG
fibrinogen gamma chain
chr11_-_8892900 0.31 ENST00000526155.1
ENST00000524757.1
ENST00000527392.1
ENST00000534665.1
ENST00000525169.1
ENST00000527516.1
ENST00000533471.1
ST5
suppression of tumorigenicity 5
chr17_+_4675175 0.27 ENST00000270560.3
TM4SF5
transmembrane 4 L six family member 5
chr15_+_96875657 0.25 ENST00000559679.1
ENST00000394171.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr9_+_2158485 0.23 ENST00000417599.1
ENST00000382185.1
ENST00000382183.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr16_+_12059091 0.23 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr4_+_89300158 0.21 ENST00000502870.1
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr9_+_2158443 0.21 ENST00000302401.3
ENST00000324954.5
ENST00000423555.1
ENST00000382186.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_+_154377669 0.20 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr17_+_1665253 0.18 ENST00000254722.4
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr19_-_10687948 0.18 ENST00000592285.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr19_+_51897742 0.18 ENST00000600765.1
CTD-2616J11.14
CTD-2616J11.14
chr17_-_27467418 0.17 ENST00000528564.1
MYO18A
myosin XVIIIA
chr17_+_76311791 0.16 ENST00000586321.1
AC061992.2
AC061992.2
chr3_-_112329110 0.16 ENST00000479368.1
CCDC80
coiled-coil domain containing 80
chr22_-_42322795 0.15 ENST00000291232.3
TNFRSF13C
tumor necrosis factor receptor superfamily, member 13C
chr14_-_22005062 0.15 ENST00000317492.5
SALL2
spalt-like transcription factor 2
chr19_-_10687907 0.15 ENST00000589348.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr19_+_45973360 0.15 ENST00000589593.1
FOSB
FBJ murine osteosarcoma viral oncogene homolog B
chr15_-_44069513 0.14 ENST00000433927.1
ELL3
elongation factor RNA polymerase II-like 3
chr7_+_16793160 0.14 ENST00000262067.4
TSPAN13
tetraspanin 13
chr8_+_62200509 0.14 ENST00000519846.1
ENST00000518592.1
ENST00000325897.4
CLVS1
clavesin 1
chr5_+_66254698 0.13 ENST00000405643.1
ENST00000407621.1
ENST00000432426.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr18_+_56532100 0.13 ENST00000588456.1
ENST00000589481.1
ENST00000591049.1
ZNF532
zinc finger protein 532
chr2_+_233390863 0.12 ENST00000449596.1
ENST00000543200.1
CHRND
cholinergic receptor, nicotinic, delta (muscle)
chr15_+_96876340 0.12 ENST00000453270.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr5_+_35856951 0.11 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R
interleukin 7 receptor
chr19_+_41281060 0.11 ENST00000594436.1
ENST00000597784.1
MIA
melanoma inhibitory activity
chr19_+_41281282 0.11 ENST00000263369.3
MIA
melanoma inhibitory activity
chr10_-_129924468 0.11 ENST00000368653.3
MKI67
marker of proliferation Ki-67
chr17_-_45056606 0.11 ENST00000322329.3
RPRML
reprimo-like
chr11_-_4629367 0.11 ENST00000533021.1
TRIM68
tripartite motif containing 68
chr2_+_120687335 0.11 ENST00000544261.1
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr10_-_129924611 0.11 ENST00000368654.3
MKI67
marker of proliferation Ki-67
chr6_-_32920794 0.11 ENST00000395305.3
ENST00000395303.3
ENST00000374843.4
ENST00000429234.1
HLA-DMA
XXbac-BPG181M17.5
major histocompatibility complex, class II, DM alpha
Uncharacterized protein
chr7_-_87104963 0.11 ENST00000359206.3
ENST00000358400.3
ENST00000265723.4
ABCB4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr8_+_58055238 0.10 ENST00000519314.1
ENST00000519241.1
RP11-513O17.2
RP11-513O17.2
chr4_-_467892 0.10 ENST00000506646.1
ENST00000505900.1
ZNF721
zinc finger protein 721
chr5_+_148206156 0.10 ENST00000305988.4
ADRB2
adrenoceptor beta 2, surface
chr11_-_125550726 0.10 ENST00000315608.3
ENST00000530048.1
ACRV1
acrosomal vesicle protein 1
chr11_+_34642656 0.10 ENST00000257831.3
ENST00000450654.2
EHF
ets homologous factor
chr11_-_4629388 0.10 ENST00000526337.1
ENST00000300747.5
TRIM68
tripartite motif containing 68
chr16_+_50308028 0.10 ENST00000566761.2
ADCY7
adenylate cyclase 7
chr17_+_68071389 0.10 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr9_-_123638633 0.10 ENST00000456291.1
PHF19
PHD finger protein 19
chr2_-_89157161 0.10 ENST00000390237.2
IGKC
immunoglobulin kappa constant
chr14_-_83262540 0.10 ENST00000554451.1
RP11-11K13.1
RP11-11K13.1
chr4_-_185655212 0.10 ENST00000541971.1
MLF1IP
centromere protein U
chr11_+_1049862 0.10 ENST00000534584.1
RP13-870H17.3
RP13-870H17.3
chrX_+_37639302 0.10 ENST00000545017.1
ENST00000536160.1
CYBB
cytochrome b-245, beta polypeptide
chr7_-_84121858 0.09 ENST00000448879.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr17_+_45908974 0.09 ENST00000269025.4
LRRC46
leucine rich repeat containing 46
chr19_-_10687983 0.09 ENST00000587069.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr3_-_158450475 0.09 ENST00000237696.5
RARRES1
retinoic acid receptor responder (tazarotene induced) 1
chr5_-_141338377 0.09 ENST00000510041.1
PCDH12
protocadherin 12
chr2_+_108994466 0.09 ENST00000272452.2
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr2_-_142888573 0.09 ENST00000434794.1
LRP1B
low density lipoprotein receptor-related protein 1B
chr1_-_54879140 0.09 ENST00000525990.1
SSBP3
single stranded DNA binding protein 3
chr1_-_114414316 0.09 ENST00000528414.1
ENST00000538253.1
ENST00000460620.1
ENST00000420377.2
ENST00000525799.1
ENST00000359785.5
PTPN22
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr19_+_36393367 0.08 ENST00000246551.4
HCST
hematopoietic cell signal transducer
chr12_-_50419177 0.08 ENST00000454520.2
ENST00000546595.1
ENST00000548824.1
ENST00000549777.1
ENST00000546723.1
ENST00000427314.2
ENST00000552157.1
ENST00000552310.1
ENST00000548644.1
ENST00000312377.5
ENST00000546786.1
ENST00000550149.1
ENST00000546764.1
ENST00000552004.1
ENST00000548320.1
ENST00000547905.1
ENST00000550651.1
ENST00000551145.1
ENST00000434422.1
ENST00000552921.1
RACGAP1
Rac GTPase activating protein 1
chr17_-_26694979 0.08 ENST00000438614.1
VTN
vitronectin
chr7_-_130066571 0.08 ENST00000492389.1
CEP41
centrosomal protein 41kDa
chr2_-_204400113 0.08 ENST00000319170.5
RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr9_-_95244781 0.08 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr4_-_144826682 0.08 ENST00000358615.4
ENST00000437468.2
GYPE
glycophorin E (MNS blood group)
chr1_-_109655377 0.08 ENST00000369948.3
C1orf194
chromosome 1 open reading frame 194
chr1_-_179834311 0.08 ENST00000553856.1
IFRG15
Homo sapiens torsin A interacting protein 2 (TOR1AIP2), transcript variant 1, mRNA.
chr11_-_64703354 0.08 ENST00000532246.1
ENST00000279168.2
GPHA2
glycoprotein hormone alpha 2
chr18_-_46895066 0.08 ENST00000583225.1
ENST00000584983.1
ENST00000583280.1
ENST00000581738.1
DYM
dymeclin
chr18_-_30050395 0.08 ENST00000269209.6
ENST00000399218.4
GAREM
GRB2 associated, regulator of MAPK1
chr5_+_111964133 0.08 ENST00000508879.1
ENST00000507565.1
RP11-159K7.2
RP11-159K7.2
chr11_-_71823266 0.08 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
ANAPC15
anaphase promoting complex subunit 15
chr21_+_38593701 0.08 ENST00000440629.1
AP001432.14
AP001432.14
chr1_-_110306562 0.08 ENST00000369805.3
EPS8L3
EPS8-like 3
chr17_-_62340581 0.08 ENST00000258991.3
ENST00000583738.1
ENST00000584379.1
TEX2
testis expressed 2
chr3_-_114343039 0.08 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr7_-_105332084 0.08 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr1_-_173793458 0.07 ENST00000356198.2
CENPL
centromere protein L
chr6_-_41673552 0.07 ENST00000419574.1
ENST00000445214.1
TFEB
transcription factor EB
chr1_+_164528616 0.07 ENST00000340699.3
PBX1
pre-B-cell leukemia homeobox 1
chr6_-_10412600 0.07 ENST00000379608.3
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr2_-_111291587 0.07 ENST00000437167.1
RGPD6
RANBP2-like and GRIP domain containing 6
chr19_+_47813110 0.07 ENST00000355085.3
C5AR1
complement component 5a receptor 1
chr17_-_39280419 0.07 ENST00000394014.1
KRTAP4-12
keratin associated protein 4-12
chr11_+_20044375 0.07 ENST00000525322.1
ENST00000530408.1
NAV2
neuron navigator 2
chr1_-_109655355 0.07 ENST00000369945.3
C1orf194
chromosome 1 open reading frame 194
chr17_-_56494908 0.07 ENST00000577716.1
RNF43
ring finger protein 43
chr4_+_48807155 0.07 ENST00000504654.1
OCIAD1
OCIA domain containing 1
chr11_-_8892464 0.07 ENST00000527347.1
ENST00000526241.1
ENST00000526126.1
ENST00000530938.1
ENST00000526057.1
ST5
suppression of tumorigenicity 5
chr2_-_231989808 0.07 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr17_-_18266818 0.07 ENST00000583780.1
SHMT1
serine hydroxymethyltransferase 1 (soluble)
chr2_+_11696464 0.07 ENST00000234142.5
GREB1
growth regulation by estrogen in breast cancer 1
chr21_+_17566643 0.07 ENST00000419952.1
ENST00000445461.2
LINC00478
long intergenic non-protein coding RNA 478
chrX_+_53449887 0.07 ENST00000375327.3
RIBC1
RIB43A domain with coiled-coils 1
chr7_+_114055052 0.07 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2
forkhead box P2
chr19_+_55417499 0.07 ENST00000291890.4
ENST00000447255.1
ENST00000598576.1
ENST00000594765.1
NCR1
natural cytotoxicity triggering receptor 1
chr7_+_45067265 0.07 ENST00000474617.1
CCM2
cerebral cavernous malformation 2
chr11_-_125550764 0.07 ENST00000527795.1
ACRV1
acrosomal vesicle protein 1
chr17_-_18266660 0.07 ENST00000582653.1
ENST00000352886.6
SHMT1
serine hydroxymethyltransferase 1 (soluble)
chr19_+_41281416 0.07 ENST00000597140.1
MIA
melanoma inhibitory activity
chr5_+_140174429 0.06 ENST00000520672.2
ENST00000378132.1
ENST00000526136.1
PCDHA2
protocadherin alpha 2
chr17_+_37856253 0.06 ENST00000540147.1
ENST00000584450.1
ERBB2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr16_+_2014941 0.06 ENST00000531523.1
SNHG9
small nucleolar RNA host gene 9 (non-protein coding)
chr17_-_57229155 0.06 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr1_+_46713404 0.06 ENST00000371975.4
ENST00000469835.1
RAD54L
RAD54-like (S. cerevisiae)
chr11_+_71900703 0.06 ENST00000393681.2
FOLR1
folate receptor 1 (adult)
chr17_-_18266797 0.06 ENST00000316694.3
ENST00000539052.1
SHMT1
serine hydroxymethyltransferase 1 (soluble)
chr19_-_49140609 0.06 ENST00000601104.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr19_-_13900972 0.06 ENST00000397557.1
AC008686.1
Uncharacterized protein
chr17_+_34171081 0.06 ENST00000585577.1
TAF15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
chr13_-_67802549 0.06 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr19_-_15311713 0.06 ENST00000601011.1
ENST00000263388.2
NOTCH3
notch 3
chr3_+_63898275 0.06 ENST00000538065.1
ATXN7
ataxin 7
chr9_-_75695323 0.06 ENST00000419959.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr17_-_56494882 0.06 ENST00000584437.1
RNF43
ring finger protein 43
chrX_-_54069253 0.06 ENST00000425862.1
ENST00000433120.1
PHF8
PHD finger protein 8
chr16_+_2014993 0.06 ENST00000564014.1
SNHG9
small nucleolar RNA host gene 9 (non-protein coding)
chr7_-_38948774 0.06 ENST00000395969.2
ENST00000414632.1
ENST00000310301.4
VPS41
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr16_-_53737722 0.06 ENST00000569716.1
ENST00000562588.1
ENST00000562230.1
ENST00000379925.3
ENST00000563746.1
ENST00000568653.3
RPGRIP1L
RPGRIP1-like
chr17_+_68071458 0.06 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr16_-_53737795 0.06 ENST00000262135.4
ENST00000564374.1
ENST00000566096.1
RPGRIP1L
RPGRIP1-like
chr6_-_135271260 0.06 ENST00000265605.2
ALDH8A1
aldehyde dehydrogenase 8 family, member A1
chr16_-_4838255 0.06 ENST00000591624.1
ENST00000396693.5
SEPT12
septin 12
chr19_+_48958766 0.06 ENST00000342291.2
KCNJ14
potassium inwardly-rectifying channel, subfamily J, member 14
chr18_-_48723690 0.06 ENST00000406189.3
MEX3C
mex-3 RNA binding family member C
chr1_+_153940741 0.06 ENST00000431292.1
CREB3L4
cAMP responsive element binding protein 3-like 4
chr2_-_99485825 0.06 ENST00000423771.1
KIAA1211L
KIAA1211-like
chr6_-_32908765 0.06 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr16_+_2533020 0.06 ENST00000562105.1
TBC1D24
TBC1 domain family, member 24
chr11_-_60720002 0.06 ENST00000538739.1
SLC15A3
solute carrier family 15 (oligopeptide transporter), member 3
chr14_-_23285011 0.06 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr17_-_56494713 0.06 ENST00000407977.2
RNF43
ring finger protein 43
chr18_+_55712915 0.06 ENST00000592846.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr12_+_57828521 0.06 ENST00000309668.2
INHBC
inhibin, beta C
chr5_+_176784837 0.06 ENST00000408923.3
RGS14
regulator of G-protein signaling 14
chr17_-_7018128 0.06 ENST00000380952.2
ENST00000254850.7
ASGR2
asialoglycoprotein receptor 2
chr1_+_176432298 0.06 ENST00000367661.3
ENST00000367662.3
PAPPA2
pappalysin 2
chr1_-_49242553 0.06 ENST00000371833.3
BEND5
BEN domain containing 5
chr3_-_158450231 0.06 ENST00000479756.1
RARRES1
retinoic acid receptor responder (tazarotene induced) 1
chr19_-_13227534 0.06 ENST00000588229.1
ENST00000357720.4
TRMT1
tRNA methyltransferase 1 homolog (S. cerevisiae)
chr6_-_135271219 0.06 ENST00000367847.2
ENST00000367845.2
ALDH8A1
aldehyde dehydrogenase 8 family, member A1
chr11_+_59522532 0.06 ENST00000337979.4
ENST00000535361.1
STX3
syntaxin 3
chr18_+_52385068 0.06 ENST00000586570.1
RAB27B
RAB27B, member RAS oncogene family
chr7_-_92146729 0.06 ENST00000541751.1
PEX1
peroxisomal biogenesis factor 1
chr11_-_104034827 0.05 ENST00000393158.2
PDGFD
platelet derived growth factor D
chr2_+_79412357 0.05 ENST00000466387.1
CTNNA2
catenin (cadherin-associated protein), alpha 2
chr2_+_87755054 0.05 ENST00000423846.1
LINC00152
long intergenic non-protein coding RNA 152
chr3_-_187388173 0.05 ENST00000287641.3
SST
somatostatin
chr6_+_37225540 0.05 ENST00000373491.3
TBC1D22B
TBC1 domain family, member 22B
chr6_-_32908792 0.05 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr14_-_95623607 0.05 ENST00000531162.1
ENST00000529720.1
ENST00000343455.3
DICER1
dicer 1, ribonuclease type III
chr16_-_70323422 0.05 ENST00000261772.8
AARS
alanyl-tRNA synthetase
chrX_-_41782683 0.05 ENST00000378163.1
ENST00000378154.1
CASK
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr17_+_37856214 0.05 ENST00000445658.2
ERBB2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr10_-_82049424 0.05 ENST00000372213.3
MAT1A
methionine adenosyltransferase I, alpha
chr19_-_44123734 0.05 ENST00000598676.1
ZNF428
zinc finger protein 428
chr19_-_13227463 0.05 ENST00000437766.1
ENST00000221504.8
TRMT1
tRNA methyltransferase 1 homolog (S. cerevisiae)
chr1_-_161039753 0.05 ENST00000368015.1
ARHGAP30
Rho GTPase activating protein 30
chr12_-_59314246 0.05 ENST00000320743.3
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr17_-_26695013 0.05 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr7_+_151771377 0.05 ENST00000434507.1
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr21_-_36421535 0.05 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
RUNX1
runt-related transcription factor 1
chr12_-_106697974 0.05 ENST00000553039.1
CKAP4
cytoskeleton-associated protein 4
chr12_+_54674482 0.05 ENST00000547708.1
ENST00000340913.6
ENST00000551702.1
ENST00000330752.8
ENST00000547276.1
HNRNPA1
heterogeneous nuclear ribonucleoprotein A1
chr4_+_86749045 0.05 ENST00000514229.1
ARHGAP24
Rho GTPase activating protein 24
chr4_-_113627966 0.05 ENST00000505632.1
RP11-148B6.2
RP11-148B6.2
chr3_+_149689066 0.05 ENST00000593416.1
AC117395.1
LOC646903 protein; Uncharacterized protein
chr17_-_7531121 0.05 ENST00000573566.1
ENST00000269298.5
SAT2
spermidine/spermine N1-acetyltransferase family member 2
chr17_-_39780819 0.05 ENST00000311208.8
KRT17
keratin 17
chr1_+_61542922 0.05 ENST00000407417.3
NFIA
nuclear factor I/A
chr7_-_1980128 0.05 ENST00000437877.1
MAD1L1
MAD1 mitotic arrest deficient-like 1 (yeast)
chr15_+_91498089 0.05 ENST00000394258.2
ENST00000555155.1
RCCD1
RCC1 domain containing 1
chr14_-_23285069 0.05 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr18_+_55711575 0.05 ENST00000356462.6
ENST00000400345.3
ENST00000589054.1
ENST00000256832.7
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr11_+_71900572 0.05 ENST00000312293.4
FOLR1
folate receptor 1 (adult)
chr12_-_58159361 0.05 ENST00000546567.1
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr6_-_31704282 0.05 ENST00000375784.3
ENST00000375779.2
CLIC1
chloride intracellular channel 1
chr17_+_26800296 0.05 ENST00000444914.3
ENST00000314669.5
SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr11_+_118272328 0.05 ENST00000524422.1
ATP5L
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
chr17_-_18266765 0.05 ENST00000354098.3
SHMT1
serine hydroxymethyltransferase 1 (soluble)
chr6_+_45296391 0.05 ENST00000371436.6
ENST00000576263.1
RUNX2
runt-related transcription factor 2
chr19_-_18337240 0.05 ENST00000262805.12
PDE4C
phosphodiesterase 4C, cAMP-specific
chr3_+_35680339 0.05 ENST00000450234.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr2_+_217082311 0.05 ENST00000597904.1
RP11-566E18.3
RP11-566E18.3
chrX_+_103294483 0.05 ENST00000355016.3
H2BFM
H2B histone family, member M
chr3_-_114477962 0.05 ENST00000471418.1
ZBTB20
zinc finger and BTB domain containing 20
chr1_+_104104379 0.05 ENST00000435302.1
AMY2B
amylase, alpha 2B (pancreatic)
chr15_+_42131011 0.05 ENST00000458483.1
PLA2G4B
phospholipase A2, group IVB (cytosolic)
chr1_+_165600436 0.05 ENST00000367888.4
ENST00000367885.1
ENST00000367884.2
MGST3
microsomal glutathione S-transferase 3
chr4_+_41937131 0.05 ENST00000504986.1
ENST00000508448.1
ENST00000513702.1
ENST00000325094.5
TMEM33
transmembrane protein 33
chr9_+_2159850 0.05 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr10_+_60936921 0.05 ENST00000373878.3
PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr2_+_26915584 0.05 ENST00000302909.3
KCNK3
potassium channel, subfamily K, member 3
chr19_-_44124019 0.05 ENST00000300811.3
ZNF428
zinc finger protein 428
chr21_-_36421401 0.05 ENST00000486278.2
RUNX1
runt-related transcription factor 1
chr1_+_173793777 0.05 ENST00000239457.5
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr18_-_78005231 0.05 ENST00000470488.2
ENST00000353265.3
PARD6G
par-6 family cell polarity regulator gamma

Network of associatons between targets according to the STRING database.

First level regulatory network of GFI1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.2 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.1 0.2 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.1 0.2 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.2 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.2 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.1 GO:0071231 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.0 0.1 GO:1901656 cellular response to mycotoxin(GO:0036146) glycoside transport(GO:1901656) cellular response to bile acid(GO:1903413)
0.0 0.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.1 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.1 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.0 0.1 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.2 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.1 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.1 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.1 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.1 GO:0038185 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.1 GO:2000437 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.0 0.1 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.0 GO:1901657 glycosyl compound metabolic process(GO:1901657)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.1 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.0 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.0 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.1 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.0 0.1 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.0 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.0 0.3 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 0.0 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0 0.1 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.1 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.0 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.0 GO:0061010 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.1 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.1 GO:0072103 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:1903936 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.0 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.0 GO:0030120 vesicle coat(GO:0030120)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.0 GO:0036457 keratohyalin granule(GO:0036457)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0030249 cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249)
0.1 0.2 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.2 GO:0070905 serine binding(GO:0070905)
0.0 0.1 GO:0031862 prostanoid receptor binding(GO:0031862)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 0.0 GO:0019808 polyamine binding(GO:0019808)
0.0 0.1 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.1 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.0 0.1 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.1 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.0 GO:0032090 Pyrin domain binding(GO:0032090)
0.0 0.0 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.0 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.0 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.1 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling