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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for GLIS3

Z-value: 0.25

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Transcription factors associated with GLIS3

Gene Symbol Gene ID Gene Info
GLIS3
ENSG00000107249.17 GLIS family zinc finger 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GLIS3hg19_v2_chr9_-_4299874_4299916-0.475.3e-01Click!

Activity profile of GLIS3 motif

Sorted Z-values of GLIS3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_4675175 0.32 ENST00000270560.3
TM4SF5
transmembrane 4 L six family member 5
chr11_+_68451943 0.21 ENST00000265643.3
GAL
galanin/GMAP prepropeptide
chr1_+_16062820 0.16 ENST00000294454.5
SLC25A34
solute carrier family 25, member 34
chr3_-_160167540 0.15 ENST00000496222.1
ENST00000471396.1
ENST00000471155.1
ENST00000309784.4
TRIM59
tripartite motif containing 59
chr5_+_172386517 0.13 ENST00000519522.1
RPL26L1
ribosomal protein L26-like 1
chr5_+_41925325 0.10 ENST00000296812.2
ENST00000281623.3
ENST00000509134.1
FBXO4
F-box protein 4
chr18_+_11752040 0.09 ENST00000423027.3
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr13_-_20767037 0.09 ENST00000382848.4
GJB2
gap junction protein, beta 2, 26kDa
chr19_+_1495362 0.09 ENST00000395479.4
REEP6
receptor accessory protein 6
chr19_+_41281060 0.09 ENST00000594436.1
ENST00000597784.1
MIA
melanoma inhibitory activity
chr5_+_72509751 0.08 ENST00000515556.1
ENST00000513379.1
ENST00000427584.2
RP11-60A8.1
RP11-60A8.1
chr14_+_105190514 0.08 ENST00000330877.2
ADSSL1
adenylosuccinate synthase like 1
chr9_-_139658965 0.08 ENST00000316144.5
LCN15
lipocalin 15
chr16_+_89686991 0.08 ENST00000393092.3
DPEP1
dipeptidase 1 (renal)
chr7_+_65958693 0.08 ENST00000445681.1
ENST00000452565.1
GS1-124K5.4
GS1-124K5.4
chr5_-_137090028 0.08 ENST00000314940.4
HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr1_-_53018654 0.08 ENST00000257177.4
ENST00000355809.4
ENST00000528642.1
ENST00000470626.1
ENST00000371544.3
ZCCHC11
zinc finger, CCHC domain containing 11
chr5_+_172386419 0.07 ENST00000265100.2
ENST00000519239.1
RPL26L1
ribosomal protein L26-like 1
chr1_-_22215192 0.07 ENST00000374673.3
HSPG2
heparan sulfate proteoglycan 2
chr1_-_247095236 0.07 ENST00000478568.1
AHCTF1
AT hook containing transcription factor 1
chr17_-_5015129 0.06 ENST00000575898.1
ENST00000416429.2
ZNF232
zinc finger protein 232
chr11_+_393428 0.06 ENST00000533249.1
ENST00000527442.1
PKP3
plakophilin 3
chr8_-_29120604 0.06 ENST00000521515.1
KIF13B
kinesin family member 13B
chr7_+_150758642 0.06 ENST00000488420.1
SLC4A2
solute carrier family 4 (anion exchanger), member 2
chr22_+_18834324 0.05 ENST00000342005.4
AC008132.13
Uncharacterized protein
chr17_-_33446820 0.05 ENST00000592577.1
ENST00000590016.1
ENST00000345365.6
ENST00000360276.3
ENST00000357906.3
RAD51D
RAD51 paralog D
chr17_-_73178599 0.05 ENST00000578238.1
SUMO2
small ubiquitin-like modifier 2
chr17_-_73179046 0.05 ENST00000314523.7
ENST00000420826.2
SUMO2
small ubiquitin-like modifier 2
chr20_+_18447771 0.05 ENST00000377603.4
POLR3F
polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
chr9_-_98279241 0.04 ENST00000437951.1
ENST00000375274.2
ENST00000430669.2
ENST00000468211.2
PTCH1
patched 1
chr4_+_164265035 0.04 ENST00000338566.3
NPY5R
neuropeptide Y receptor Y5
chr3_-_25824872 0.04 ENST00000308710.5
NGLY1
N-glycanase 1
chr1_-_53019059 0.04 ENST00000484723.2
ENST00000524582.1
ZCCHC11
zinc finger, CCHC domain containing 11
chr19_-_48673465 0.04 ENST00000598938.1
LIG1
ligase I, DNA, ATP-dependent
chr18_+_11751493 0.04 ENST00000269162.5
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr8_-_74791051 0.04 ENST00000453587.2
ENST00000602969.1
ENST00000602593.1
ENST00000419880.3
ENST00000517608.1
UBE2W
ubiquitin-conjugating enzyme E2W (putative)
chr17_+_80818231 0.04 ENST00000576996.1
TBCD
tubulin folding cofactor D
chr11_+_66886717 0.04 ENST00000398645.2
KDM2A
lysine (K)-specific demethylase 2A
chr7_-_50518022 0.04 ENST00000356889.4
ENST00000420829.1
ENST00000448788.1
ENST00000395556.2
ENST00000422854.1
ENST00000435566.1
ENST00000433017.1
FIGNL1
fidgetin-like 1
chr6_+_89791507 0.04 ENST00000354922.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr1_+_110527308 0.04 ENST00000369799.5
AHCYL1
adenosylhomocysteinase-like 1
chr17_-_3819751 0.03 ENST00000225538.3
P2RX1
purinergic receptor P2X, ligand-gated ion channel, 1
chr3_+_127348005 0.03 ENST00000342480.6
PODXL2
podocalyxin-like 2
chr6_+_44191290 0.03 ENST00000371755.3
ENST00000371740.5
ENST00000371731.1
ENST00000393841.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr1_-_157108266 0.03 ENST00000326786.4
ETV3
ets variant 3
chr6_+_44191507 0.03 ENST00000371724.1
ENST00000371713.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr1_+_59250815 0.03 ENST00000544621.1
ENST00000419531.2
RP4-794H19.2
long intergenic non-protein coding RNA 1135
chr1_-_42800860 0.03 ENST00000445886.1
ENST00000361346.1
ENST00000361776.1
FOXJ3
forkhead box J3
chr11_+_134855246 0.03 ENST00000597621.1
AP003062.1
CDNA FLJ27342 fis, clone TST02993; Uncharacterized protein
chr17_+_7792101 0.03 ENST00000358181.4
ENST00000330494.7
CHD3
chromodomain helicase DNA binding protein 3
chr6_+_24495067 0.03 ENST00000357578.3
ENST00000546278.1
ENST00000491546.1
ALDH5A1
aldehyde dehydrogenase 5 family, member A1
chr8_-_12051576 0.02 ENST00000524571.2
ENST00000533852.2
ENST00000533513.1
ENST00000448228.2
ENST00000534520.1
ENST00000321602.8
FAM86B1
family with sequence similarity 86, member B1
chr20_-_44718538 0.02 ENST00000290231.6
ENST00000372291.3
NCOA5
nuclear receptor coactivator 5
chr11_-_68671264 0.02 ENST00000362034.2
MRPL21
mitochondrial ribosomal protein L21
chr1_-_42801540 0.02 ENST00000372573.1
FOXJ3
forkhead box J3
chr19_-_14224969 0.02 ENST00000589994.1
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chrX_+_118370288 0.02 ENST00000535419.1
PGRMC1
progesterone receptor membrane component 1
chr20_-_23969416 0.02 ENST00000335694.4
GGTLC1
gamma-glutamyltransferase light chain 1
chr3_-_160167508 0.02 ENST00000479460.1
TRIM59
tripartite motif containing 59
chr11_+_68671310 0.02 ENST00000255078.3
ENST00000539224.1
IGHMBP2
immunoglobulin mu binding protein 2
chr9_-_130742792 0.01 ENST00000373095.1
FAM102A
family with sequence similarity 102, member A
chr1_+_33207381 0.01 ENST00000401073.2
KIAA1522
KIAA1522
chr7_+_23636992 0.01 ENST00000307471.3
ENST00000409765.1
CCDC126
coiled-coil domain containing 126
chr15_+_91478493 0.01 ENST00000418476.2
UNC45A
unc-45 homolog A (C. elegans)
chr4_-_84255935 0.01 ENST00000513463.1
HPSE
heparanase
chr9_-_88874519 0.01 ENST00000376001.3
ENST00000339137.3
C9orf153
chromosome 9 open reading frame 153
chr19_-_56092187 0.01 ENST00000325421.4
ENST00000592239.1
ZNF579
zinc finger protein 579
chrX_+_64887512 0.01 ENST00000360270.5
MSN
moesin
chr17_-_77925806 0.01 ENST00000574241.2
TBC1D16
TBC1 domain family, member 16
chr6_+_24495185 0.01 ENST00000348925.2
ALDH5A1
aldehyde dehydrogenase 5 family, member A1
chr22_+_50628999 0.01 ENST00000395827.1
TRABD
TraB domain containing
chr6_+_33172407 0.01 ENST00000374662.3
HSD17B8
hydroxysteroid (17-beta) dehydrogenase 8
chr17_+_5389605 0.01 ENST00000576988.1
ENST00000576570.1
ENST00000573759.1
MIS12
MIS12 kinetochore complex component
chr16_-_3285144 0.01 ENST00000431561.3
ENST00000396870.4
ZNF200
zinc finger protein 200
chr20_-_18447667 0.01 ENST00000262547.5
ENST00000329494.5
ENST00000357236.4
DZANK1
double zinc ribbon and ankyrin repeat domains 1
chr11_-_18813110 0.01 ENST00000396168.1
PTPN5
protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
chr18_+_3451584 0.00 ENST00000551541.1
TGIF1
TGFB-induced factor homeobox 1
chr3_-_25824925 0.00 ENST00000396649.3
ENST00000428257.1
ENST00000280700.5
NGLY1
N-glycanase 1
chr9_-_116061476 0.00 ENST00000441031.3
RNF183
ring finger protein 183
chr11_-_8680383 0.00 ENST00000299550.6
TRIM66
tripartite motif containing 66
chr2_-_241759622 0.00 ENST00000320389.7
ENST00000498729.2
KIF1A
kinesin family member 1A
chr1_+_1950763 0.00 ENST00000378585.4
GABRD
gamma-aminobutyric acid (GABA) A receptor, delta
chr2_-_241737128 0.00 ENST00000404283.3
KIF1A
kinesin family member 1A
chr21_-_46330545 0.00 ENST00000320216.6
ENST00000397852.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

Network of associatons between targets according to the STRING database.

First level regulatory network of GLIS3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0051795 positive regulation of catagen(GO:0051795)
0.0 0.1 GO:0043605 antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605)
0.0 0.1 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.1 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.0 GO:1903461 Okazaki fragment processing involved in mitotic DNA replication(GO:1903461)
0.0 0.0 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.1 GO:0008283 cell proliferation(GO:0008283)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.0 GO:0000224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity(GO:0000224)
0.0 0.0 GO:0001602 peptide YY receptor activity(GO:0001601) pancreatic polypeptide receptor activity(GO:0001602)