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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for GZF1

Z-value: 0.33

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Transcription factors associated with GZF1

Gene Symbol Gene ID Gene Info
GZF1
ENSG00000125812.11 GDNF inducible zinc finger protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GZF1hg19_v2_chr20_+_23342783_233429570.881.2e-01Click!

Activity profile of GZF1 motif

Sorted Z-values of GZF1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_114035026 0.27 ENST00000570269.1
RP11-553L6.5
RP11-553L6.5
chr2_-_150444300 0.25 ENST00000303319.5
MMADHC
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr3_+_30647994 0.22 ENST00000295754.5
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr2_-_150444116 0.21 ENST00000428879.1
ENST00000422782.2
MMADHC
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr12_+_102513950 0.20 ENST00000378128.3
ENST00000327680.2
ENST00000541394.1
ENST00000543784.1
PARPBP
PARP1 binding protein
chr10_+_89264625 0.20 ENST00000371996.4
ENST00000371994.4
MINPP1
multiple inositol-polyphosphate phosphatase 1
chr12_-_76478386 0.20 ENST00000535020.2
NAP1L1
nucleosome assembly protein 1-like 1
chr19_+_38880695 0.16 ENST00000587947.1
ENST00000338502.4
SPRED3
sprouty-related, EVH1 domain containing 3
chr4_+_2451700 0.15 ENST00000506607.1
RP11-503N18.3
Uncharacterized protein
chr1_-_226374373 0.15 ENST00000366812.5
ACBD3
acyl-CoA binding domain containing 3
chr12_-_76478417 0.14 ENST00000552342.1
NAP1L1
nucleosome assembly protein 1-like 1
chr1_+_32757718 0.14 ENST00000428704.1
HDAC1
histone deacetylase 1
chr5_+_170814803 0.13 ENST00000521672.1
ENST00000351986.6
ENST00000393820.2
ENST00000523622.1
NPM1
nucleophosmin (nucleolar phosphoprotein B23, numatrin)
chr3_+_30648066 0.12 ENST00000359013.4
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr15_+_44580955 0.11 ENST00000345795.2
ENST00000360824.3
CASC4
cancer susceptibility candidate 4
chr12_-_76478446 0.11 ENST00000393263.3
ENST00000548044.1
ENST00000547704.1
ENST00000431879.3
ENST00000549596.1
ENST00000550934.1
ENST00000551600.1
ENST00000547479.1
ENST00000547773.1
ENST00000544816.1
ENST00000542344.1
ENST00000548273.1
NAP1L1
nucleosome assembly protein 1-like 1
chr14_-_59950724 0.10 ENST00000481608.1
L3HYPDH
L-3-hydroxyproline dehydratase (trans-)
chr18_-_53303123 0.10 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chr13_+_98086445 0.09 ENST00000245304.4
RAP2A
RAP2A, member of RAS oncogene family
chr5_+_92919043 0.09 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr7_-_26904317 0.08 ENST00000345317.2
SKAP2
src kinase associated phosphoprotein 2
chr3_-_79816965 0.08 ENST00000464233.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr7_-_27183263 0.08 ENST00000222726.3
HOXA5
homeobox A5
chr17_-_70588936 0.08 ENST00000453722.2
LINC00511
long intergenic non-protein coding RNA 511
chr14_-_92413353 0.07 ENST00000556154.1
FBLN5
fibulin 5
chr10_+_14880364 0.07 ENST00000441647.1
HSPA14
heat shock 70kDa protein 14
chr1_-_11107280 0.06 ENST00000400897.3
ENST00000400898.3
MASP2
mannan-binding lectin serine peptidase 2
chr9_-_124976154 0.06 ENST00000482062.1
LHX6
LIM homeobox 6
chr7_-_105029812 0.05 ENST00000482897.1
SRPK2
SRSF protein kinase 2
chr7_-_105029329 0.05 ENST00000393651.3
ENST00000460391.1
SRPK2
SRSF protein kinase 2
chr12_+_107168418 0.05 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8B
RIC8 guanine nucleotide exchange factor B
chr3_-_87039662 0.04 ENST00000494229.1
VGLL3
vestigial like 3 (Drosophila)
chr10_-_126849626 0.04 ENST00000530884.1
CTBP2
C-terminal binding protein 2
chr19_+_36157715 0.04 ENST00000379013.2
ENST00000222275.2
UPK1A
uroplakin 1A
chr10_+_14880287 0.04 ENST00000437161.2
HSPA14
heat shock 70kDa protein 14
chr11_+_101918153 0.03 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70
chromosome 11 open reading frame 70
chr4_-_147442817 0.03 ENST00000507030.1
SLC10A7
solute carrier family 10, member 7
chr1_+_32757668 0.03 ENST00000373548.3
HDAC1
histone deacetylase 1
chr9_-_124976185 0.03 ENST00000464484.2
LHX6
LIM homeobox 6
chr19_-_14628645 0.03 ENST00000598235.1
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr6_+_30524663 0.03 ENST00000376560.3
PRR3
proline rich 3
chr14_-_53619816 0.03 ENST00000323669.5
ENST00000395606.1
ENST00000357758.3
DDHD1
DDHD domain containing 1
chr11_-_17498348 0.03 ENST00000389817.3
ENST00000302539.4
ABCC8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr10_-_16563870 0.03 ENST00000298943.3
C1QL3
complement component 1, q subcomponent-like 3
chr12_-_102513843 0.02 ENST00000551744.2
ENST00000552283.1
NUP37
nucleoporin 37kDa
chrX_+_153238220 0.02 ENST00000425274.1
TMEM187
transmembrane protein 187
chr9_-_14308004 0.02 ENST00000493697.1
NFIB
nuclear factor I/B
chr7_-_75115548 0.02 ENST00000453279.2
POM121C
POM121 transmembrane nucleoporin C
chr3_-_87040233 0.01 ENST00000398399.2
VGLL3
vestigial like 3 (Drosophila)
chr6_+_7108210 0.01 ENST00000467782.1
ENST00000334984.6
ENST00000349384.6
RREB1
ras responsive element binding protein 1
chr4_-_147442982 0.01 ENST00000511374.1
ENST00000264986.3
SLC10A7
solute carrier family 10, member 7
chr10_+_60028818 0.01 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr6_+_30525051 0.01 ENST00000376557.3
PRR3
proline rich 3
chr20_+_42086525 0.01 ENST00000244020.3
SRSF6
serine/arginine-rich splicing factor 6
chr8_+_23430157 0.01 ENST00000399967.3
FP15737
FP15737
chrX_+_54835493 0.01 ENST00000396224.1
MAGED2
melanoma antigen family D, 2
chr19_-_52150053 0.01 ENST00000599649.1
ENST00000429354.3
ENST00000360844.6
ENST00000222107.4
SIGLEC5
SIGLEC14
SIGLEC5
SIGLEC5
sialic acid binding Ig-like lectin 14
sialic acid binding Ig-like lectin 5
chr19_-_44384291 0.00 ENST00000324394.6
ZNF404
zinc finger protein 404
chr19_-_36545128 0.00 ENST00000538849.1
THAP8
THAP domain containing 8
chr16_+_87636474 0.00 ENST00000284262.2
JPH3
junctophilin 3
chr10_-_126849588 0.00 ENST00000411419.2
CTBP2
C-terminal binding protein 2
chr14_-_92413727 0.00 ENST00000267620.10
FBLN5
fibulin 5

Network of associatons between targets according to the STRING database.

First level regulatory network of GZF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0002661 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.1 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.0 0.5 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0060699 regulation of endoribonuclease activity(GO:0060699)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.2 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 0.1 GO:0047661 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.1 GO:0001855 complement component C4b binding(GO:0001855)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)