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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for HMGA1

Z-value: 3.42

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Transcription factors associated with HMGA1

Gene Symbol Gene ID Gene Info
HMGA1
ENSG00000137309.15 high mobility group AT-hook 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMGA1hg19_v2_chr6_+_34204642_34204664-0.445.6e-01Click!

Activity profile of HMGA1 motif

Sorted Z-values of HMGA1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_155484155 6.49 ENST00000509493.1
FGB
fibrinogen beta chain
chr2_-_228244013 4.93 ENST00000304568.3
TM4SF20
transmembrane 4 L six family member 20
chr12_-_71551652 4.71 ENST00000546561.1
TSPAN8
tetraspanin 8
chr7_-_35013217 4.05 ENST00000446375.1
DPY19L1
dpy-19-like 1 (C. elegans)
chr4_+_155484103 3.63 ENST00000302068.4
FGB
fibrinogen beta chain
chr9_-_47314222 3.42 ENST00000420228.1
ENST00000438517.1
ENST00000414020.1
AL953854.2
AL953854.2
chrY_+_15418467 3.31 ENST00000595988.1
AC010877.1
Uncharacterized protein
chr3_-_148939598 3.26 ENST00000455472.3
CP
ceruloplasmin (ferroxidase)
chr1_-_197036364 2.83 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr4_+_54927213 2.69 ENST00000595906.1
AC110792.1
HCG2027126; Uncharacterized protein
chr4_-_155533787 2.61 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG
fibrinogen gamma chain
chr1_+_241695670 2.57 ENST00000366557.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr13_+_113760098 2.50 ENST00000346342.3
ENST00000541084.1
ENST00000375581.3
F7
coagulation factor VII (serum prothrombin conversion accelerator)
chr5_+_92919043 2.48 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr1_+_81001398 2.46 ENST00000418041.1
ENST00000443104.1
RP5-887A10.1
RP5-887A10.1
chr9_-_3469181 2.24 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr17_-_64225508 2.11 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr1_+_196621002 1.95 ENST00000367429.4
ENST00000439155.2
CFH
complement factor H
chr15_-_99789736 1.93 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
TTC23
tetratricopeptide repeat domain 23
chr14_+_58797974 1.90 ENST00000417477.2
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr3_-_195310802 1.84 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr1_+_81106951 1.81 ENST00000443565.1
RP5-887A10.1
RP5-887A10.1
chr17_+_70036164 1.69 ENST00000602013.1
AC007461.1
Uncharacterized protein
chr7_-_16844611 1.66 ENST00000401412.1
ENST00000419304.2
AGR2
anterior gradient 2
chr17_-_64216748 1.63 ENST00000585162.1
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr10_-_101825151 1.61 ENST00000441382.1
CPN1
carboxypeptidase N, polypeptide 1
chr4_-_89442940 1.60 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr8_-_66701319 1.52 ENST00000379419.4
PDE7A
phosphodiesterase 7A
chr3_+_149191723 1.52 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr20_-_52612468 1.50 ENST00000422805.1
BCAS1
breast carcinoma amplified sequence 1
chr16_+_12059091 1.48 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr9_-_123812542 1.47 ENST00000223642.1
C5
complement component 5
chr8_+_107738240 1.44 ENST00000449762.2
ENST00000297447.6
OXR1
oxidation resistance 1
chr1_+_196621156 1.43 ENST00000359637.2
CFH
complement factor H
chr10_+_94594351 1.42 ENST00000371552.4
EXOC6
exocyst complex component 6
chr17_-_57229155 1.36 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr3_-_112360116 1.35 ENST00000206423.3
ENST00000439685.2
CCDC80
coiled-coil domain containing 80
chr4_-_164265984 1.32 ENST00000511901.1
NPY1R
neuropeptide Y receptor Y1
chr8_-_95274536 1.31 ENST00000297596.2
ENST00000396194.2
GEM
GTP binding protein overexpressed in skeletal muscle
chr11_+_93479588 1.30 ENST00000526335.1
C11orf54
chromosome 11 open reading frame 54
chr3_-_127541194 1.30 ENST00000453507.2
MGLL
monoglyceride lipase
chr16_+_21244986 1.29 ENST00000311620.5
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr4_-_71532339 1.26 ENST00000254801.4
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr4_-_110723335 1.26 ENST00000394634.2
CFI
complement factor I
chr4_-_110723194 1.25 ENST00000394635.3
CFI
complement factor I
chr8_+_27491381 1.22 ENST00000337221.4
SCARA3
scavenger receptor class A, member 3
chr5_+_68860949 1.22 ENST00000507595.1
GTF2H2C
general transcription factor IIH, polypeptide 2C
chr4_-_110723134 1.20 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr21_+_35552978 1.19 ENST00000428914.2
ENST00000609062.1
ENST00000609947.1
LINC00310
long intergenic non-protein coding RNA 310
chrX_+_37639264 1.18 ENST00000378588.4
CYBB
cytochrome b-245, beta polypeptide
chr5_+_68462944 1.15 ENST00000506572.1
CCNB1
cyclin B1
chr14_+_56078695 1.15 ENST00000416613.1
KTN1
kinectin 1 (kinesin receptor)
chr1_+_229440129 1.14 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr2_+_120687335 1.14 ENST00000544261.1
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr8_+_27491572 1.11 ENST00000301904.3
SCARA3
scavenger receptor class A, member 3
chr15_-_55657428 1.11 ENST00000568543.1
CCPG1
cell cycle progression 1
chr12_+_20963632 1.10 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr9_-_69229650 1.10 ENST00000416428.1
CBWD6
COBW domain containing 6
chr18_-_25616519 1.10 ENST00000399380.3
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr12_-_50419177 1.06 ENST00000454520.2
ENST00000546595.1
ENST00000548824.1
ENST00000549777.1
ENST00000546723.1
ENST00000427314.2
ENST00000552157.1
ENST00000552310.1
ENST00000548644.1
ENST00000312377.5
ENST00000546786.1
ENST00000550149.1
ENST00000546764.1
ENST00000552004.1
ENST00000548320.1
ENST00000547905.1
ENST00000550651.1
ENST00000551145.1
ENST00000434422.1
ENST00000552921.1
RACGAP1
Rac GTPase activating protein 1
chr18_+_3466248 1.06 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
RP11-838N2.4
chr3_-_148939835 1.06 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr5_-_125930929 1.06 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr16_+_53920795 1.05 ENST00000431610.2
ENST00000460382.1
FTO
fat mass and obesity associated
chr4_+_90033968 1.04 ENST00000317005.2
TIGD2
tigger transposable element derived 2
chr16_-_46649905 1.04 ENST00000569702.1
SHCBP1
SHC SH2-domain binding protein 1
chr4_-_105416039 1.04 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr15_+_76352178 1.04 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr4_+_95972822 1.04 ENST00000509540.1
ENST00000440890.2
BMPR1B
bone morphogenetic protein receptor, type IB
chr1_-_108231101 1.03 ENST00000544443.1
ENST00000415432.2
VAV3
vav 3 guanine nucleotide exchange factor
chr7_-_130066571 1.02 ENST00000492389.1
CEP41
centrosomal protein 41kDa
chr12_+_20963647 1.00 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr15_+_55611401 1.00 ENST00000566999.1
PIGB
phosphatidylinositol glycan anchor biosynthesis, class B
chr10_-_115423792 0.98 ENST00000369360.3
ENST00000360478.3
ENST00000359988.3
ENST00000369358.4
NRAP
nebulin-related anchoring protein
chr5_-_87516448 0.98 ENST00000511218.1
TMEM161B
transmembrane protein 161B
chr14_-_90085458 0.98 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3
forkhead box N3
chr12_+_69742121 0.98 ENST00000261267.2
ENST00000549690.1
ENST00000548839.1
LYZ
lysozyme
chr2_+_179318295 0.97 ENST00000442710.1
DFNB59
deafness, autosomal recessive 59
chr8_-_90993869 0.96 ENST00000517772.1
NBN
nibrin
chr14_-_70883708 0.96 ENST00000256366.4
SYNJ2BP
synaptojanin 2 binding protein
chr10_-_102045882 0.96 ENST00000579542.1
BLOC1S2
biogenesis of lysosomal organelles complex-1, subunit 2
chr12_-_102591604 0.95 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr3_+_142342228 0.95 ENST00000337777.3
PLS1
plastin 1
chr21_+_35553045 0.94 ENST00000416145.1
ENST00000430922.1
ENST00000419881.2
LINC00310
long intergenic non-protein coding RNA 310
chrX_-_20236970 0.93 ENST00000379548.4
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr15_-_63448973 0.92 ENST00000462430.1
RPS27L
ribosomal protein S27-like
chr18_+_47901365 0.92 ENST00000285116.3
SKA1
spindle and kinetochore associated complex subunit 1
chr6_-_151773232 0.91 ENST00000444024.1
ENST00000367303.4
RMND1
required for meiotic nuclear division 1 homolog (S. cerevisiae)
chr7_+_133615169 0.91 ENST00000541309.1
EXOC4
exocyst complex component 4
chr9_+_97562440 0.90 ENST00000395357.2
C9orf3
chromosome 9 open reading frame 3
chr5_+_145316120 0.88 ENST00000359120.4
SH3RF2
SH3 domain containing ring finger 2
chr4_+_142557771 0.88 ENST00000514653.1
IL15
interleukin 15
chr10_+_94590910 0.86 ENST00000371547.4
EXOC6
exocyst complex component 6
chr4_+_141294628 0.86 ENST00000512749.1
ENST00000608372.1
ENST00000506597.1
ENST00000394201.4
ENST00000510586.1
SCOC
short coiled-coil protein
chr2_+_103378472 0.86 ENST00000412401.2
TMEM182
transmembrane protein 182
chr3_-_151176497 0.86 ENST00000282466.3
IGSF10
immunoglobulin superfamily, member 10
chr21_+_17792672 0.85 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr12_-_10978957 0.84 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr1_+_78470530 0.84 ENST00000370763.5
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr18_+_72922710 0.83 ENST00000322038.5
TSHZ1
teashirt zinc finger homeobox 1
chr16_-_66907139 0.83 ENST00000561579.2
NAE1
NEDD8 activating enzyme E1 subunit 1
chr15_+_52155001 0.83 ENST00000544199.1
TMOD3
tropomodulin 3 (ubiquitous)
chrX_-_135962876 0.82 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RBMX
RNA binding motif protein, X-linked
chr11_+_1295809 0.81 ENST00000598274.1
AC136297.1
Uncharacterized protein
chr16_+_53412368 0.81 ENST00000565189.1
RP11-44F14.2
RP11-44F14.2
chr2_+_190541153 0.81 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ANKAR
ankyrin and armadillo repeat containing
chr8_+_107738343 0.80 ENST00000521592.1
OXR1
oxidation resistance 1
chr15_-_65117807 0.80 ENST00000559239.1
ENST00000268043.4
ENST00000333425.6
PIF1
PIF1 5'-to-3' DNA helicase
chr18_+_47901408 0.80 ENST00000398452.2
ENST00000417656.2
ENST00000488454.1
ENST00000494518.1
SKA1
spindle and kinetochore associated complex subunit 1
chr7_-_81635106 0.80 ENST00000443883.1
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr4_-_153303658 0.79 ENST00000296555.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chrX_+_37639302 0.79 ENST00000545017.1
ENST00000536160.1
CYBB
cytochrome b-245, beta polypeptide
chr4_+_142557717 0.78 ENST00000320650.4
ENST00000296545.7
IL15
interleukin 15
chr4_+_109571740 0.78 ENST00000361564.4
OSTC
oligosaccharyltransferase complex subunit (non-catalytic)
chr19_+_49458107 0.77 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BAX
BCL2-associated X protein
chr15_-_37390482 0.77 ENST00000559085.1
ENST00000397624.3
MEIS2
Meis homeobox 2
chr12_+_28410128 0.77 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr14_+_61449076 0.77 ENST00000526105.1
SLC38A6
solute carrier family 38, member 6
chr15_+_36887069 0.77 ENST00000566807.1
ENST00000567389.1
ENST00000562877.1
C15orf41
chromosome 15 open reading frame 41
chr15_+_69857515 0.77 ENST00000559477.1
RP11-279F6.1
RP11-279F6.1
chr6_-_119031228 0.77 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L
centrosomal protein 85kDa-like
chr1_+_174670143 0.76 ENST00000367687.1
ENST00000347255.2
RABGAP1L
RAB GTPase activating protein 1-like
chr4_-_159094194 0.76 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B
family with sequence similarity 198, member B
chr20_-_14318248 0.76 ENST00000378053.3
ENST00000341420.4
FLRT3
fibronectin leucine rich transmembrane protein 3
chr8_-_101733794 0.76 ENST00000523555.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr5_-_125930877 0.75 ENST00000510111.2
ENST00000509270.1
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chrX_-_11129229 0.75 ENST00000608176.1
ENST00000433747.2
ENST00000608576.1
ENST00000608916.1
RP11-120D5.1
RP11-120D5.1
chr7_-_140482926 0.75 ENST00000496384.2
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr1_-_220219775 0.75 ENST00000609181.1
EPRS
glutamyl-prolyl-tRNA synthetase
chr6_-_39197226 0.74 ENST00000359534.3
KCNK5
potassium channel, subfamily K, member 5
chr3_+_164924716 0.74 ENST00000470138.1
ENST00000498616.1
RP11-85M11.2
RP11-85M11.2
chr4_-_152147579 0.74 ENST00000304527.4
ENST00000455740.1
ENST00000424281.1
ENST00000409598.4
SH3D19
SH3 domain containing 19
chr7_+_36450169 0.74 ENST00000428612.1
ANLN
anillin, actin binding protein
chr6_+_26158343 0.73 ENST00000377777.4
ENST00000289316.2
HIST1H2BD
histone cluster 1, H2bd
chr22_-_29107919 0.73 ENST00000434810.1
ENST00000456369.1
CHEK2
checkpoint kinase 2
chr9_-_104145795 0.73 ENST00000259407.2
BAAT
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr2_-_152589670 0.73 ENST00000604864.1
ENST00000603639.1
NEB
nebulin
chr16_+_53483983 0.72 ENST00000544545.1
RBL2
retinoblastoma-like 2 (p130)
chr10_-_116444371 0.72 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr15_+_35270552 0.72 ENST00000391457.2
AC114546.1
HCG37415; PRO1914; Uncharacterized protein
chr5_+_162930114 0.72 ENST00000280969.5
MAT2B
methionine adenosyltransferase II, beta
chr6_-_26056695 0.72 ENST00000343677.2
HIST1H1C
histone cluster 1, H1c
chr15_+_63682335 0.71 ENST00000559379.1
ENST00000559821.1
RP11-321G12.1
RP11-321G12.1
chr10_-_38265517 0.71 ENST00000302609.7
ZNF25
zinc finger protein 25
chr1_+_219347203 0.71 ENST00000366927.3
LYPLAL1
lysophospholipase-like 1
chr1_+_53480598 0.70 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
SCP2
sterol carrier protein 2
chr11_+_28129795 0.70 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
METTL15
methyltransferase like 15
chr3_+_189349162 0.70 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63
tumor protein p63
chr3_-_149095652 0.70 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr2_+_162101247 0.69 ENST00000439050.1
ENST00000436506.1
AC009299.3
AC009299.3
chr9_-_39239171 0.68 ENST00000358144.2
CNTNAP3
contactin associated protein-like 3
chr4_-_83765613 0.67 ENST00000503937.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr7_+_116502605 0.66 ENST00000458284.2
ENST00000490693.1
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr2_+_113321939 0.66 ENST00000458012.2
POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chr1_-_40042073 0.66 ENST00000372858.3
PABPC4
poly(A) binding protein, cytoplasmic 4 (inducible form)
chrX_-_20237059 0.66 ENST00000457145.1
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr2_+_64069459 0.65 ENST00000445915.2
ENST00000475462.1
UGP2
UDP-glucose pyrophosphorylase 2
chr19_+_41509851 0.65 ENST00000593831.1
ENST00000330446.5
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr5_-_43515125 0.65 ENST00000509489.1
C5orf34
chromosome 5 open reading frame 34
chr12_+_14572070 0.65 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
ATF7IP
activating transcription factor 7 interacting protein
chr1_+_219347186 0.65 ENST00000366928.5
LYPLAL1
lysophospholipase-like 1
chr12_-_122879969 0.64 ENST00000540304.1
CLIP1
CAP-GLY domain containing linker protein 1
chr5_+_158690089 0.63 ENST00000296786.6
UBLCP1
ubiquitin-like domain containing CTD phosphatase 1
chr1_-_169555779 0.63 ENST00000367797.3
ENST00000367796.3
F5
coagulation factor V (proaccelerin, labile factor)
chr11_+_100784231 0.63 ENST00000531183.1
ARHGAP42
Rho GTPase activating protein 42
chr15_-_63449663 0.63 ENST00000439025.1
RPS27L
ribosomal protein S27-like
chr7_-_56119238 0.61 ENST00000275605.3
ENST00000395471.3
PSPH
phosphoserine phosphatase
chr1_+_215740709 0.61 ENST00000259154.4
KCTD3
potassium channel tetramerization domain containing 3
chr1_+_207943667 0.61 ENST00000462968.2
CD46
CD46 molecule, complement regulatory protein
chrX_-_41449204 0.61 ENST00000378179.3
CASK
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr5_-_135701164 0.61 ENST00000355180.3
ENST00000426057.2
ENST00000513104.1
TRPC7
transient receptor potential cation channel, subfamily C, member 7
chr6_+_76311568 0.61 ENST00000370014.3
SENP6
SUMO1/sentrin specific peptidase 6
chr17_+_38516907 0.61 ENST00000578774.1
CTD-2267D19.3
Uncharacterized protein
chr7_-_55620433 0.61 ENST00000418904.1
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr3_-_197300194 0.60 ENST00000358186.2
ENST00000431056.1
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr5_+_68513622 0.60 ENST00000512880.1
ENST00000602380.1
MRPS36
mitochondrial ribosomal protein S36
chr12_+_41086297 0.60 ENST00000551295.2
CNTN1
contactin 1
chr12_-_120189900 0.60 ENST00000546026.1
CIT
citron (rho-interacting, serine/threonine kinase 21)
chr16_+_53241854 0.59 ENST00000565803.1
CHD9
chromodomain helicase DNA binding protein 9
chr8_+_66619277 0.59 ENST00000521247.2
ENST00000527155.1
MTFR1
mitochondrial fission regulator 1
chr14_+_39736582 0.58 ENST00000556148.1
ENST00000348007.3
CTAGE5
CTAGE family, member 5
chr6_-_52859046 0.58 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
GSTA4
glutathione S-transferase alpha 4
chr6_-_116575226 0.58 ENST00000420283.1
TSPYL4
TSPY-like 4
chr6_+_10556215 0.58 ENST00000316170.3
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr13_-_45010939 0.57 ENST00000261489.2
TSC22D1
TSC22 domain family, member 1
chr2_-_225434538 0.57 ENST00000409096.1
CUL3
cullin 3
chr15_+_71228826 0.57 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
LRRC49
leucine rich repeat containing 49
chr15_+_57511609 0.56 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
TCF12
transcription factor 12
chr12_-_49581152 0.56 ENST00000550811.1
TUBA1A
tubulin, alpha 1a
chr9_+_2159850 0.56 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr13_+_108870714 0.56 ENST00000375898.3
ABHD13
abhydrolase domain containing 13
chr9_-_21142144 0.56 ENST00000380229.2
IFNW1
interferon, omega 1
chr1_+_179851410 0.56 ENST00000271583.3
ENST00000606911.2
TOR1AIP1
torsin A interacting protein 1
chr12_+_6602517 0.56 ENST00000315579.5
ENST00000539714.1
NCAPD2
non-SMC condensin I complex, subunit D2
chr10_-_69597810 0.56 ENST00000483798.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chrX_-_135962923 0.55 ENST00000565438.1
RBMX
RNA binding motif protein, X-linked
chr1_+_81771806 0.55 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr10_-_69597828 0.55 ENST00000339758.7
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr1_-_150980828 0.55 ENST00000361936.5
ENST00000361738.6
FAM63A
family with sequence similarity 63, member A
chr1_-_116926718 0.54 ENST00000598661.1
AL136376.1
Uncharacterized protein

Network of associatons between targets according to the STRING database.

First level regulatory network of HMGA1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:1905225 response to thyrotropin-releasing hormone(GO:1905225)
0.8 10.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.6 1.7 GO:0045062 extrathymic T cell selection(GO:0045062)
0.5 1.6 GO:0030070 insulin processing(GO:0030070)
0.5 1.8 GO:2000097 negative regulation of lipoprotein oxidation(GO:0034443) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.5 1.8 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.4 1.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.4 1.3 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.4 2.0 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.4 0.8 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.4 1.2 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.4 4.0 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.4 2.5 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.3 1.0 GO:0042245 RNA repair(GO:0042245)
0.3 1.3 GO:1904106 protein localization to microvillus(GO:1904106)
0.3 1.3 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.3 3.5 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.3 1.9 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.3 1.1 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.2 0.7 GO:0031106 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.2 0.7 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.2 1.7 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.2 1.1 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.2 1.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 1.5 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.2 1.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 0.7 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 0.5 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.2 0.7 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.2 2.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 0.8 GO:0060023 soft palate development(GO:0060023)
0.2 1.0 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.2 1.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 1.0 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.7 GO:0007525 somatic muscle development(GO:0007525)
0.1 1.5 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 0.4 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.1 0.5 GO:0032571 response to vitamin K(GO:0032571)
0.1 0.4 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 2.5 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.7 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 2.6 GO:0031639 plasminogen activation(GO:0031639)
0.1 1.4 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 1.5 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.8 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 0.8 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.1 0.6 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.3 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.1 0.3 GO:0006429 glutaminyl-tRNA aminoacylation(GO:0006425) leucyl-tRNA aminoacylation(GO:0006429)
0.1 0.4 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.3 GO:0033488 cholesterol biosynthetic process via 24,25-dihydrolanosterol(GO:0033488)
0.1 0.5 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.1 2.3 GO:0009650 UV protection(GO:0009650)
0.1 0.3 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.1 0.7 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.8 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1 0.3 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.1 0.4 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.6 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.1 0.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.6 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.3 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 1.0 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.1 0.4 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 0.7 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.3 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 0.3 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.3 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.3 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 0.2 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 2.5 GO:0006825 copper ion transport(GO:0006825)
0.1 0.7 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.6 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.9 GO:0007000 nucleolus organization(GO:0007000)
0.1 1.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.9 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.1 0.3 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.8 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 0.8 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.7 GO:0019530 taurine metabolic process(GO:0019530)
0.1 0.3 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.1 0.8 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 1.0 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 0.3 GO:1990535 neuron projection maintenance(GO:1990535)
0.1 0.5 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 1.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.6 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.1 0.4 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.5 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.5 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 2.6 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 0.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 0.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.8 GO:0042246 tissue regeneration(GO:0042246)
0.1 0.5 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.1 0.4 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.1 GO:0035357 peroxisome proliferator activated receptor signaling pathway(GO:0035357)
0.1 0.5 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 0.6 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 3.9 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 0.9 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.4 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.3 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.6 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.3 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 2.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 1.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.3 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.4 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.0 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0039533 regulation of MDA-5 signaling pathway(GO:0039533)
0.0 0.7 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 3.4 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.8 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 1.6 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 1.7 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.8 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.4 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.4 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.6 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.8 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.6 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.4 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.7 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 1.2 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.5 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.6 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.1 GO:0060667 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529) mammary gland specification(GO:0060594) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.4 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.4 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.4 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 1.0 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0021502 neural fold elevation formation(GO:0021502) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 1.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 2.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.3 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.1 GO:0006711 estrogen catabolic process(GO:0006711)
0.0 0.6 GO:0061045 negative regulation of wound healing(GO:0061045)
0.0 0.2 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.2 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 1.0 GO:0019835 cytolysis(GO:0019835)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.7 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.3 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.3 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.1 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.0 0.4 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.5 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.3 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.5 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.2 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 1.6 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.7 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.5 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.7 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.2 GO:0035973 aggrephagy(GO:0035973)
0.0 0.2 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.9 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 3.4 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.6 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.4 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.6 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:1903764 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.0 GO:0060142 positive regulation of myotube differentiation(GO:0010831) regulation of syncytium formation by plasma membrane fusion(GO:0060142) positive regulation of syncytium formation by plasma membrane fusion(GO:0060143) regulation of myoblast fusion(GO:1901739) positive regulation of myoblast fusion(GO:1901741)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.0 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.4 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0000050 urea cycle(GO:0000050)
0.0 0.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.1 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.5 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.1 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.9 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.4 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.5 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.5 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.0 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.0 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:1901838 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836) positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.1 GO:0045008 depyrimidination(GO:0045008)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 12.7 GO:0005577 fibrinogen complex(GO:0005577)
0.3 0.6 GO:0098576 lumenal side of membrane(GO:0098576)
0.2 0.7 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 1.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 1.4 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 1.3 GO:0005579 membrane attack complex(GO:0005579)
0.2 3.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.2 3.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 1.1 GO:0097149 centralspindlin complex(GO:0097149)
0.2 1.0 GO:0005927 muscle tendon junction(GO:0005927)
0.2 1.3 GO:0097452 GAIT complex(GO:0097452)
0.2 1.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.7 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.6 GO:0002079 inner acrosomal membrane(GO:0002079)
0.1 1.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 1.2 GO:0000439 core TFIIH complex(GO:0000439)
0.1 1.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.8 GO:1990357 terminal web(GO:1990357)
0.1 1.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.5 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.3 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.6 GO:0000799 nuclear condensin complex(GO:0000799)
0.1 0.3 GO:0036117 hyaluranon cable(GO:0036117)
0.1 0.5 GO:1990037 Lewy body core(GO:1990037)
0.1 0.8 GO:0032584 growth cone membrane(GO:0032584)
0.1 1.5 GO:0012505 endomembrane system(GO:0012505)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.2 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1 0.6 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.6 GO:0030478 actin cap(GO:0030478)
0.1 0.6 GO:0005827 polar microtubule(GO:0005827)
0.1 0.8 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.2 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.1 1.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 1.0 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 1.2 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.3 GO:1990246 uniplex complex(GO:1990246)
0.1 0.5 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 1.0 GO:0005916 fascia adherens(GO:0005916)
0.0 1.7 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 8.0 GO:0072562 blood microparticle(GO:0072562)
0.0 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.3 GO:0031673 H zone(GO:0031673)
0.0 0.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.8 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.7 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.0 3.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.6 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.6 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.2 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.6 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.1 GO:0034455 t-UTP complex(GO:0034455)
0.0 1.0 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.7 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 2.0 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 1.3 GO:0051233 spindle midzone(GO:0051233)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.8 GO:0035371 microtubule plus-end(GO:0035371)
0.0 2.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.4 GO:0071439 clathrin complex(GO:0071439)
0.0 0.4 GO:0044754 autolysosome(GO:0044754)
0.0 1.9 GO:0005657 replication fork(GO:0005657)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 1.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 2.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.8 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.8 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.2 GO:0042581 specific granule lumen(GO:0035580) specific granule(GO:0042581)
0.0 1.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.8 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.8 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.2 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.4 1.3 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.3 4.0 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 1.3 GO:0001602 peptide YY receptor activity(GO:0001601) pancreatic polypeptide receptor activity(GO:0001602)
0.3 0.8 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.3 0.8 GO:0033677 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.3 0.8 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.3 1.0 GO:0035514 DNA demethylase activity(GO:0035514)
0.3 0.8 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.2 1.0 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.2 2.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 0.7 GO:0070538 oleic acid binding(GO:0070538)
0.2 2.6 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.2 0.7 GO:0017130 poly(C) RNA binding(GO:0017130)
0.2 1.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 3.2 GO:0008494 translation activator activity(GO:0008494)
0.1 0.6 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 5.0 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 3.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 1.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.8 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.4 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 1.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.7 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.3 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.6 GO:0031208 POZ domain binding(GO:0031208)
0.1 0.3 GO:0031775 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.1 0.3 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.1 0.3 GO:0008398 sterol 14-demethylase activity(GO:0008398)
0.1 1.6 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.1 1.4 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.6 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.7 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 0.6 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.1 2.0 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.6 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.4 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.4 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.1 0.4 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 2.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 1.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.4 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.6 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 1.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 5.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 11.0 GO:0051087 chaperone binding(GO:0051087)
0.1 1.0 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.3 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.7 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.3 GO:0019863 IgE binding(GO:0019863)
0.1 0.2 GO:0070283 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.1 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.8 GO:0042731 PH domain binding(GO:0042731)
0.1 0.4 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 0.2 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.7 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 1.8 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 0.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 1.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.0 0.5 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 2.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.9 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.7 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.2 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 0.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.0 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.4 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.8 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 2.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.0 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.8 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.7 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.8 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0015248 sterol transporter activity(GO:0015248)
0.0 1.8 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.9 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.9 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.8 GO:0004871 signal transducer activity(GO:0004871)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 1.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.3 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.3 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.0 1.0 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.6 GO:0001848 complement binding(GO:0001848)
0.0 2.0 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.7 GO:0008009 chemokine activity(GO:0008009)
0.0 3.4 GO:0005178 integrin binding(GO:0005178)
0.0 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.3 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.3 GO:0004576 oligosaccharyl transferase activity(GO:0004576)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.3 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 1.3 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.8 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.2 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.0 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.6 GO:0005507 copper ion binding(GO:0005507)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 12.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 0.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 2.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 3.6 PID INSULIN PATHWAY Insulin Pathway
0.0 0.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 2.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 3.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.6 PID ATM PATHWAY ATM pathway
0.0 1.1 PID MYC PATHWAY C-MYC pathway
0.0 1.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 2.2 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.5 PID BMP PATHWAY BMP receptor signaling
0.0 0.6 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.2 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 16.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 8.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.3 2.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.9 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 2.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 4.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 3.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.9 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 1.2 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 2.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 2.0 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.0 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.1 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.3 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 1.6 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 4.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.8 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 2.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.7 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.5 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.8 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.9 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 2.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.9 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.1 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 1.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation