Project

A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for HNF1A_HNF1B

Z-value: 5.56

Motif logo

Transcription factors associated with HNF1A_HNF1B

Gene Symbol Gene ID Gene Info
ENSG00000135100.13 HNF1 homeobox A
ENSG00000108753.8 HNF1 homeobox B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HNF1Ahg19_v2_chr12_+_121416437_1214164790.982.4e-02Click!
HNF1Bhg19_v2_chr17_-_36105009_36105060-0.001.0e+00Click!

Activity profile of HNF1A_HNF1B motif

Sorted Z-values of HNF1A_HNF1B motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_64225508 12.50 ENST00000205948.6
apolipoprotein H (beta-2-glycoprotein I)
chr19_-_36304201 11.32 ENST00000301175.3
proline dehydrogenase (oxidase) 2
chr5_+_176514413 9.25 ENST00000513166.1
fibroblast growth factor receptor 4
chr9_-_123812542 8.90 ENST00000223642.1
complement component 5
chr10_+_115312766 8.12 ENST00000351270.3
hyaluronan binding protein 2
chr4_+_155484103 7.66 ENST00000302068.4
fibrinogen beta chain
chr1_+_48688357 7.57 ENST00000533824.1
ENST00000438567.2
ENST00000236495.5
ENST00000420136.2
solute carrier family 5 (sodium/sugar cotransporter), member 9
chr1_-_197036364 7.56 ENST00000367412.1
coagulation factor XIII, B polypeptide
chr2_+_38177575 7.40 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
regulator of microtubule dynamics 2
chr4_+_3443614 7.29 ENST00000382774.3
ENST00000511533.1
HGF activator
chr4_+_155484155 7.15 ENST00000509493.1
fibrinogen beta chain
chr10_+_99344071 7.05 ENST00000370647.4
ENST00000370646.4
4-hydroxy-2-oxoglutarate aldolase 1
chr9_-_116861337 6.66 ENST00000374118.3
kinesin family member 12
chr5_+_176513895 6.60 ENST00000503708.1
ENST00000393648.2
ENST00000514472.1
ENST00000502906.1
ENST00000292410.3
ENST00000510911.1
fibroblast growth factor receptor 4
chr7_-_50633078 6.45 ENST00000444124.2
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr16_+_20775024 6.37 ENST00000289416.5
acyl-CoA synthetase medium-chain family member 3
chr8_-_95220775 6.18 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
cadherin 17, LI cadherin (liver-intestine)
chr19_+_49467232 5.96 ENST00000599784.1
ENST00000594305.1
CTD-2639E6.9
chr4_-_155511887 5.81 ENST00000302053.3
ENST00000403106.3
fibrinogen alpha chain
chr20_-_7921090 5.77 ENST00000378789.3
hydroxyacid oxidase (glycolate oxidase) 1
chr1_+_207277632 5.56 ENST00000421786.1
complement component 4 binding protein, alpha
chr2_-_228244013 5.50 ENST00000304568.3
transmembrane 4 L six family member 20
chr1_+_18807424 5.43 ENST00000400664.1
kelch domain containing 7A
chr16_-_66952779 5.36 ENST00000570262.1
ENST00000394055.3
ENST00000299752.4
cadherin 16, KSP-cadherin
chr5_+_176513868 5.27 ENST00000292408.4
fibroblast growth factor receptor 4
chr4_-_110723335 5.19 ENST00000394634.2
complement factor I
chr1_+_207277590 5.07 ENST00000367070.3
complement component 4 binding protein, alpha
chr16_-_66952742 4.87 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
cadherin 16, KSP-cadherin
chr10_+_115312825 4.64 ENST00000537906.1
ENST00000541666.1
hyaluronan binding protein 2
chr4_+_141264597 4.33 ENST00000338517.4
ENST00000394203.3
ENST00000506322.1
short coiled-coil protein
chr4_-_110723194 4.23 ENST00000394635.3
complement factor I
chr20_+_43029911 4.18 ENST00000443598.2
ENST00000316099.4
ENST00000415691.2
hepatocyte nuclear factor 4, alpha
chr16_+_21244986 4.16 ENST00000311620.5
ankyrin repeat and sterile alpha motif domain containing 4B
chr4_-_110723134 4.15 ENST00000510800.1
ENST00000512148.1
complement factor I
chr8_-_17752996 4.13 ENST00000381841.2
ENST00000427924.1
fibrinogen-like 1
chr16_+_20775358 3.97 ENST00000440284.2
acyl-CoA synthetase medium-chain family member 3
chr10_+_101542462 3.94 ENST00000370449.4
ENST00000370434.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr5_-_138718973 3.88 ENST00000353963.3
ENST00000348729.3
solute carrier family 23 (ascorbic acid transporter), member 1
chr8_-_124749609 3.83 ENST00000262219.6
ENST00000419625.1
annexin A13
chr11_-_64660916 3.72 ENST00000413053.1
microRNA 194-2
chr16_-_69385681 3.50 ENST00000288025.3
transmembrane emp24 protein transport domain containing 6
chr2_-_47572105 3.05 ENST00000419035.1
ENST00000448713.1
ENST00000450550.1
ENST00000413185.2
AC073283.4
chr14_-_94759595 2.92 ENST00000261994.4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr11_-_111649015 2.91 ENST00000529841.1
RP11-108O10.2
chr10_+_99344104 2.85 ENST00000555577.1
ENST00000370649.3
phosphatidylinositol 4-kinase type 2 alpha
Phosphatidylinositol 4-kinase type 2-alpha; Uncharacterized protein
chr17_+_73642486 2.76 ENST00000579469.1
small integral membrane protein 6
chr12_-_39837192 2.64 ENST00000361961.3
ENST00000395670.3
kinesin family member 21A
chr14_-_94759408 2.49 ENST00000554723.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr14_-_94759361 2.48 ENST00000393096.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr19_+_50016610 2.31 ENST00000596975.1
Fc fragment of IgG, receptor, transporter, alpha
chr14_+_65170820 2.30 ENST00000555982.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr6_-_52628271 2.17 ENST00000493422.1
glutathione S-transferase alpha 2
chr17_+_73642315 2.15 ENST00000556126.2
small integral membrane protein 6
chr12_+_100867486 2.01 ENST00000548884.1
nuclear receptor subfamily 1, group H, member 4
chr14_-_94854926 1.98 ENST00000402629.1
ENST00000556091.1
ENST00000554720.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr1_-_207206092 1.94 ENST00000359470.5
ENST00000461135.2
chromosome 1 open reading frame 116
chr14_+_21156915 1.94 ENST00000397990.4
ENST00000555597.1
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr1_-_229406746 1.85 ENST00000429227.1
ENST00000436334.1
RP5-1061H20.4
chr19_-_49565254 1.84 ENST00000593537.1
neurotrophin 4
chr19_+_50016411 1.83 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
Fc fragment of IgG, receptor, transporter, alpha
chr20_+_42187682 1.80 ENST00000373092.3
ENST00000373077.1
serum/glucocorticoid regulated kinase 2
chr9_-_215744 1.75 ENST00000382387.2
chromosome 9 open reading frame 66
chr16_+_89696692 1.59 ENST00000261615.4
dipeptidase 1 (renal)
chr11_-_117695449 1.58 ENST00000292079.2
FXYD domain containing ion transport regulator 2
chr17_+_26800296 1.56 ENST00000444914.3
ENST00000314669.5
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr4_-_987164 1.46 ENST00000398520.2
solute carrier family 26 (anion exchanger), member 1
chr17_+_68071389 1.42 ENST00000283936.1
ENST00000392671.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr4_-_76944621 1.39 ENST00000306602.1
chemokine (C-X-C motif) ligand 10
chr6_+_161123270 1.29 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
plasminogen
chr1_+_84767289 1.28 ENST00000394834.3
ENST00000370669.1
sterile alpha motif domain containing 13
chr17_+_1646130 1.22 ENST00000453066.1
ENST00000324015.3
ENST00000450523.2
ENST00000453723.1
ENST00000382061.4
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr4_+_124571409 1.20 ENST00000514823.1
ENST00000511919.1
ENST00000508111.1
long intergenic non-protein coding RNA 1091
chr7_-_17598506 1.13 ENST00000451792.1
AC017060.1
chr16_-_75284758 1.09 ENST00000561970.1
breast cancer anti-estrogen resistance 1
chr12_+_100867694 1.09 ENST00000392986.3
ENST00000549996.1
nuclear receptor subfamily 1, group H, member 4
chr22_-_32651326 1.08 ENST00000266086.4
solute carrier family 5 (glucose activated ion channel), member 4
chr7_-_155601766 1.06 ENST00000430104.1
sonic hedgehog
chr20_+_42984330 1.05 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
hepatocyte nuclear factor 4, alpha
chr6_-_25874440 1.01 ENST00000361703.6
ENST00000397060.4
solute carrier family 17 (organic anion transporter), member 3
chr11_+_560956 1.00 ENST00000397582.3
ENST00000344375.4
ENST00000397583.3
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr22_+_45098067 0.98 ENST00000336985.6
ENST00000403696.1
ENST00000457960.1
ENST00000361473.5
proline rich 5 (renal)
PRR5-ARHGAP8 readthrough
chr17_+_26800648 0.94 ENST00000545060.1
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr4_-_987217 0.93 ENST00000361661.2
ENST00000398516.2
solute carrier family 26 (anion exchanger), member 1
chr22_-_38506619 0.92 ENST00000332536.5
ENST00000381669.3
BAI1-associated protein 2-like 2
chr2_+_234637754 0.91 ENST00000482026.1
ENST00000609767.1
UDP glucuronosyltransferase 1 family, polypeptide A3
UDP glucuronosyltransferase 1 family, polypeptide A8
chr17_+_26800756 0.91 ENST00000537681.1
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr12_+_100867733 0.88 ENST00000546380.1
nuclear receptor subfamily 1, group H, member 4
chr12_+_100897130 0.87 ENST00000551379.1
ENST00000188403.7
ENST00000551184.1
nuclear receptor subfamily 1, group H, member 4
chr1_+_229406847 0.82 ENST00000366690.4
RAB4A, member RAS oncogene family
chr7_+_152456904 0.82 ENST00000537264.1
ARP3 actin-related protein 3 homolog B (yeast)
chr14_-_65409502 0.78 ENST00000389614.5
glutathione peroxidase 2 (gastrointestinal)
chr7_+_141695633 0.78 ENST00000549489.2
maltase-glucoamylase (alpha-glucosidase)
chr14_+_39703084 0.76 ENST00000553728.1
cTAGE family member 5 isoform 4
chr7_+_152456829 0.76 ENST00000377776.3
ENST00000256001.8
ENST00000397282.2
ARP3 actin-related protein 3 homolog B (yeast)
chr9_+_140125385 0.76 ENST00000361134.2
solute carrier family 34 (type II sodium/phosphate contransporter), member 3
chr12_-_56615485 0.75 ENST00000549038.1
ENST00000552244.1
ring finger protein 41
chr17_+_48823975 0.74 ENST00000513969.1
ENST00000503728.1
LUC7-like 3 (S. cerevisiae)
chr13_+_96085847 0.74 ENST00000376873.3
claudin 10
chr13_-_41593425 0.74 ENST00000239882.3
E74-like factor 1 (ets domain transcription factor)
chr2_+_191792376 0.73 ENST00000409428.1
ENST00000409215.1
glutaminase
chr22_+_31002990 0.71 ENST00000423350.1
transcobalamin II
chr5_+_68860949 0.70 ENST00000507595.1
general transcription factor IIH, polypeptide 2C
chr17_+_68071458 0.69 ENST00000589377.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr16_-_87970122 0.68 ENST00000309893.2
carbonic anhydrase VA, mitochondrial
chr1_-_114430169 0.67 ENST00000393316.3
BCL2-like 15
chr4_-_69536346 0.66 ENST00000338206.5
UDP glucuronosyltransferase 2 family, polypeptide B15
chr14_-_65409438 0.65 ENST00000557049.1
glutathione peroxidase 2 (gastrointestinal)
chr4_-_100212132 0.65 ENST00000209668.2
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr10_-_75193308 0.64 ENST00000299432.2
MSS51 mitochondrial translational activator
chr4_-_109541539 0.64 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34 antisense RNA 1 (head to head)
chr4_-_1166954 0.63 ENST00000514490.1
ENST00000431380.1
ENST00000503765.1
spondin 2, extracellular matrix protein
chr4_-_166034029 0.63 ENST00000306480.6
transmembrane protein 192
chr7_+_130126165 0.63 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
mesoderm specific transcript
chr9_+_140125209 0.63 ENST00000538474.1
solute carrier family 34 (type II sodium/phosphate contransporter), member 3
chr7_+_141695671 0.62 ENST00000497673.1
ENST00000475668.2
maltase-glucoamylase (alpha-glucosidase)
chr11_+_46740730 0.58 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
coagulation factor II (thrombin)
chr18_-_70931689 0.58 ENST00000581862.1
Protein LOC400655
chr4_-_102267953 0.58 ENST00000523694.2
ENST00000507176.1
protein phosphatase 3, catalytic subunit, alpha isozyme
chr10_+_45406627 0.56 ENST00000389583.4
transmembrane protein 72
chr10_-_38146510 0.56 ENST00000395867.3
zinc finger protein 248
chr11_-_117170403 0.55 ENST00000504995.1
beta-site APP-cleaving enzyme 1
chr10_+_74451883 0.55 ENST00000373053.3
ENST00000357157.6
mitochondrial calcium uniporter
chr10_-_75226166 0.55 ENST00000544628.1
protein phosphatase 3, catalytic subunit, beta isozyme
chr19_+_6464243 0.53 ENST00000600229.1
ENST00000356762.3
crumbs homolog 3 (Drosophila)
chrX_+_120181457 0.52 ENST00000328078.1
glutamate dehydrogenase 2
chr6_-_113953705 0.51 ENST00000452675.1
RP11-367G18.1
chr3_+_107318157 0.50 ENST00000406780.1
bobby sox homolog (Drosophila)
chr19_-_43099070 0.50 ENST00000244336.5
carcinoembryonic antigen-related cell adhesion molecule 8
chr7_+_130126012 0.50 ENST00000341441.5
mesoderm specific transcript
chr10_-_52645416 0.49 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
APOBEC1 complementation factor
chr21_-_35340759 0.48 ENST00000607953.1
AP000569.9
chr17_+_41363854 0.47 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
transmembrane protein 106A
chr19_-_57678811 0.46 ENST00000554048.2
double homeobox A
chr10_-_38146482 0.45 ENST00000374648.3
zinc finger protein 248
chr16_+_22524379 0.43 ENST00000536620.1
nuclear pore complex interacting protein family, member B5
chr19_-_38916839 0.43 ENST00000433821.2
ENST00000426920.2
ENST00000587753.1
ENST00000454404.2
ENST00000293062.9
RAS guanyl releasing protein 4
chr10_-_101690650 0.43 ENST00000543621.1
dynamin binding protein
chr14_+_65171315 0.40 ENST00000394691.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr8_+_55047763 0.38 ENST00000260102.4
ENST00000519831.1
mitochondrial ribosomal protein L15
chr22_-_22337204 0.38 ENST00000430142.1
ENST00000357179.5
topoisomerase (DNA) III beta
chr12_+_20963632 0.38 ENST00000540853.1
ENST00000261196.2
solute carrier organic anion transporter family, member 1B3
chr7_-_47579188 0.37 ENST00000398879.1
ENST00000355730.3
ENST00000442536.2
ENST00000458317.2
tensin 3
chr12_+_20963647 0.36 ENST00000381545.3
solute carrier organic anion transporter family, member 1B3
chr2_+_175199674 0.35 ENST00000394967.2
Sp9 transcription factor
chr2_+_234627424 0.35 ENST00000373409.3
UDP glucuronosyltransferase 1 family, polypeptide A4
chr3_-_107596910 0.34 ENST00000464359.2
ENST00000464823.1
ENST00000466155.1
ENST00000473528.2
ENST00000608306.1
ENST00000488852.1
ENST00000608137.1
ENST00000608307.1
ENST00000609429.1
ENST00000601385.1
ENST00000475362.1
ENST00000600240.1
ENST00000600749.1
long intergenic non-protein coding RNA 635
chr3_-_192445289 0.33 ENST00000430714.1
ENST00000418610.1
ENST00000448795.1
ENST00000445105.2
fibroblast growth factor 12
chr20_+_42187608 0.33 ENST00000373100.1
serum/glucocorticoid regulated kinase 2
chr2_+_28718921 0.31 ENST00000327757.5
ENST00000422425.2
ENST00000404858.1
phospholipase B1
chr1_+_104159999 0.31 ENST00000414303.2
ENST00000423678.1
amylase, alpha 2A (pancreatic)
chr2_+_234621551 0.30 ENST00000608381.1
ENST00000373414.3
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr8_+_42873548 0.30 ENST00000533338.1
ENST00000534420.1
hook microtubule-tethering protein 3
Uncharacterized protein
chr3_-_49466686 0.29 ENST00000273598.3
ENST00000436744.2
nicolin 1
chr6_-_116833500 0.29 ENST00000356128.4
trafficking protein particle complex 3-like
chr5_-_111093167 0.28 ENST00000446294.2
ENST00000419114.2
neuronal regeneration related protein
chr22_+_31003190 0.28 ENST00000407817.3
transcobalamin II
chr5_+_67586465 0.27 ENST00000336483.5
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr22_+_31002779 0.27 ENST00000215838.3
transcobalamin II
chr19_+_41305085 0.26 ENST00000303961.4
egl-9 family hypoxia-inducible factor 2
chr6_+_31707725 0.26 ENST00000375755.3
ENST00000375742.3
ENST00000375750.3
ENST00000425703.1
ENST00000534153.4
ENST00000375703.3
ENST00000375740.3
mutS homolog 5
chr2_+_234526272 0.26 ENST00000373450.4
UDP glucuronosyltransferase 1 family, polypeptide A8
chr3_+_180319918 0.24 ENST00000296015.4
ENST00000491380.1
ENST00000412756.2
ENST00000382584.4
tetratricopeptide repeat domain 14
chr3_-_196911002 0.24 ENST00000452595.1
discs, large homolog 1 (Drosophila)
chr12_+_80838126 0.23 ENST00000266688.5
protein tyrosine phosphatase, receptor type, Q
chr4_+_108815402 0.22 ENST00000503385.1
sphingomyelin synthase 2
chr14_+_95027772 0.22 ENST00000555095.1
ENST00000298841.5
ENST00000554220.1
ENST00000553780.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr17_-_26733604 0.21 ENST00000584426.1
ENST00000584995.1
solute carrier family 46 (folate transporter), member 1
chrX_+_99899180 0.20 ENST00000373004.3
sushi-repeat containing protein, X-linked 2
chr3_+_66271410 0.18 ENST00000336733.6
solute carrier family 25 (S-adenosylmethionine carrier), member 26
chr19_-_11639931 0.16 ENST00000592312.1
ENST00000590480.1
ENST00000585318.1
ENST00000252440.7
ENST00000417981.2
ENST00000270517.7
ECSIT signalling integrator
chr7_-_44580861 0.16 ENST00000546276.1
ENST00000289547.4
ENST00000381160.3
ENST00000423141.1
NPC1-like 1
chr12_-_15865844 0.16 ENST00000543612.1
epidermal growth factor receptor pathway substrate 8
chr15_+_58724184 0.14 ENST00000433326.2
lipase, hepatic
chr3_-_137893721 0.14 ENST00000505015.2
ENST00000260803.4
debranching RNA lariats 1
chr2_-_180129484 0.13 ENST00000428443.3
SEC14 and spectrin domains 1
chr5_+_140571902 0.13 ENST00000239446.4
protocadherin beta 10
chr22_+_31003133 0.12 ENST00000405742.3
transcobalamin II
chr17_+_48823896 0.12 ENST00000511974.1
LUC7-like 3 (S. cerevisiae)
chr1_+_84630645 0.11 ENST00000394839.2
protein kinase, cAMP-dependent, catalytic, beta
chr14_+_39703112 0.10 ENST00000555143.1
ENST00000280082.3
melanoma inhibitory activity 2
chr22_-_22337154 0.09 ENST00000413067.2
ENST00000437929.1
ENST00000456075.1
ENST00000434517.1
ENST00000424393.1
ENST00000449704.1
ENST00000437103.1
topoisomerase (DNA) III beta
chr21_-_47575481 0.09 ENST00000291670.5
ENST00000397748.1
ENST00000359679.2
ENST00000355384.2
ENST00000397746.3
ENST00000397743.1
formimidoyltransferase cyclodeaminase
chr2_-_88427568 0.09 ENST00000393750.3
ENST00000295834.3
fatty acid binding protein 1, liver
chr2_-_74555350 0.08 ENST00000444570.1
solute carrier family 4 (sodium bicarbonate cotransporter), member 5
chr4_+_39408470 0.08 ENST00000257408.4
klotho beta
chr1_-_36020531 0.08 ENST00000440579.1
ENST00000494948.1
KIAA0319-like
chr12_-_56615693 0.07 ENST00000394013.2
ENST00000345093.4
ENST00000551711.1
ENST00000552656.1
ring finger protein 41
chr17_-_49021974 0.07 ENST00000501718.2
RP11-700H6.1
chr4_+_74269956 0.06 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
albumin
chr7_-_47578840 0.06 ENST00000450444.1
tensin 3
chr2_+_234601512 0.05 ENST00000305139.6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr11_+_64358722 0.05 ENST00000336464.7
solute carrier family 22 (organic anion/urate transporter), member 12
chr16_+_20462783 0.04 ENST00000574251.1
ENST00000576361.1
ENST00000417235.2
ENST00000573854.1
ENST00000424070.1
ENST00000536134.1
ENST00000219054.6
ENST00000575690.1
ENST00000571894.1
acyl-CoA synthetase medium-chain family member 2A
chr12_-_54653313 0.04 ENST00000550411.1
ENST00000439541.2
chromobox homolog 5
chr3_+_72200408 0.04 ENST00000473713.1
long intergenic non-protein coding RNA 870
chr8_+_21911054 0.04 ENST00000519850.1
ENST00000381470.3
dematin actin binding protein
chr4_-_74486109 0.04 ENST00000395777.2
Ras association (RalGDS/AF-6) domain family member 6
chr6_-_133084580 0.03 ENST00000525270.1
ENST00000530536.1
ENST00000524919.1
vanin 2
chr1_+_207262578 0.03 ENST00000243611.5
ENST00000367076.3
complement component 4 binding protein, beta
chr11_+_2405833 0.02 ENST00000527343.1
ENST00000464784.2
CD81 molecule

Network of associatons between targets according to the STRING database.

First level regulatory network of HNF1A_HNF1B

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 21.1 GO:1903412 response to bile acid(GO:1903412)
2.2 8.9 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
2.2 6.5 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) isoquinoline alkaloid metabolic process(GO:0033076)
1.8 5.5 GO:0016999 antibiotic metabolic process(GO:0016999)
1.7 18.4 GO:0046487 glyoxylate metabolic process(GO:0046487)
1.6 21.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
1.6 7.9 GO:0008218 bioluminescence(GO:0008218)
1.4 4.1 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
1.3 3.9 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
1.2 6.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
1.2 4.8 GO:0090293 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
1.2 15.6 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
1.0 4.2 GO:1904106 protein localization to microvillus(GO:1904106)
1.0 9.1 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.9 2.8 GO:0045575 basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.7 4.6 GO:0009441 glycolate metabolic process(GO:0009441)
0.6 1.8 GO:0008052 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.5 5.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.4 1.9 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.4 1.1 GO:0060738 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) positive regulation of immature T cell proliferation in thymus(GO:0033092) primary prostatic bud elongation(GO:0060516) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738) sclerotome development(GO:0061056)
0.3 1.7 GO:0044245 polysaccharide digestion(GO:0044245)
0.3 2.4 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.3 4.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.2 10.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 8.4 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.2 13.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 1.4 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.6 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.1 1.3 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.1 1.4 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.8 GO:0006789 bilirubin conjugation(GO:0006789)
0.1 1.4 GO:0015889 cobalamin transport(GO:0015889)
0.1 8.7 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.1 1.0 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.8 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 1.6 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.8 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.1 0.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 1.0 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.6 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.9 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 1.4 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.2 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.6 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.3 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.2 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.3 GO:0051026 chiasma assembly(GO:0051026)
0.0 1.1 GO:0010107 potassium ion import(GO:0010107)
0.0 1.1 GO:0035729 cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0 0.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.7 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0001897 cytolysis by symbiont of host cells(GO:0001897)
0.0 0.5 GO:0006265 DNA topological change(GO:0006265)
0.0 0.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 1.3 GO:0006953 acute-phase response(GO:0006953)
0.0 2.7 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0098856 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 6.8 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.1 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.8 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.6 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.3 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.4 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.4 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 26.0 GO:0005577 fibrinogen complex(GO:0005577)
1.5 8.9 GO:0005579 membrane attack complex(GO:0005579)
1.4 4.1 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.7 12.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.3 3.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.3 1.9 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 0.4 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.6 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.1 0.8 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 1.1 GO:0005955 calcineurin complex(GO:0005955)
0.1 4.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 0.6 GO:1990246 uniplex complex(GO:1990246)
0.1 8.4 GO:0005871 kinesin complex(GO:0005871)
0.1 5.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 3.9 GO:0009925 basal plasma membrane(GO:0009925)
0.1 9.1 GO:0044216 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1 1.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.7 GO:0000439 core TFIIH complex(GO:0000439)
0.1 1.9 GO:0031526 brush border membrane(GO:0031526)
0.1 0.9 GO:0071439 clathrin complex(GO:0071439)
0.1 19.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 5.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 26.3 GO:0030133 transport vesicle(GO:0030133)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 1.0 GO:0031932 TORC2 complex(GO:0031932)
0.0 7.4 GO:0000922 spindle pole(GO:0000922)
0.0 0.9 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.3 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 18.1 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.8 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.7 GO:0005902 microvillus(GO:0005902)
0.0 8.9 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 4.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.9 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:0032300 mismatch repair complex(GO:0032300)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 12.5 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
2.8 11.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
2.1 6.2 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
1.9 5.7 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
1.8 21.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
1.7 10.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
1.3 3.9 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
1.2 4.8 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
1.1 3.4 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
1.0 7.0 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.9 8.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.8 4.1 GO:0019770 IgG receptor activity(GO:0019770)
0.7 2.8 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.5 1.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.4 1.3 GO:1904854 proteasome core complex binding(GO:1904854)
0.3 1.8 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.3 1.7 GO:0016160 amylase activity(GO:0016160)
0.3 1.9 GO:0004522 ribonuclease A activity(GO:0004522)
0.3 0.8 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.2 3.9 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.2 8.9 GO:0008009 chemokine activity(GO:0008009)
0.2 1.6 GO:0070573 metallodipeptidase activity(GO:0070573)
0.1 11.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 2.4 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 0.6 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 2.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.5 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 1.4 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.1 GO:0043237 laminin-1 binding(GO:0043237)
0.1 1.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.6 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.6 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 6.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 0.7 GO:0004359 glutaminase activity(GO:0004359)
0.1 14.9 GO:0051087 chaperone binding(GO:0051087)
0.1 10.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 18.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 4.3 GO:0005504 fatty acid binding(GO:0005504)
0.1 2.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 0.3 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 2.5 GO:0001972 retinoic acid binding(GO:0001972)
0.1 8.4 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.5 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 1.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.3 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 4.9 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 20.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.2 10.6 PID CD40 PATHWAY CD40/CD40L signaling
0.2 18.1 PID FGF PATHWAY FGF signaling pathway
0.1 31.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.8 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 4.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 1.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 4.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.8 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.4 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.8 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 1.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.0 PID MTOR 4PATHWAY mTOR signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 28.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
1.3 21.1 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.8 22.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.5 8.2 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.4 6.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 5.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 2.8 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 1.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 3.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 0.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 2.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 3.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.8 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.7 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 1.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 5.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 2.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors