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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for HSFY2

Z-value: 0.69

Motif logo

Transcription factors associated with HSFY2

Gene Symbol Gene ID Gene Info
ENSG00000169953.11 heat shock transcription factor Y-linked 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSFY2hg19_v2_chrY_-_20935572_20935621-0.178.3e-01Click!

Activity profile of HSFY2 motif

Sorted Z-values of HSFY2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_101825151 0.77 ENST00000441382.1
carboxypeptidase N, polypeptide 1
chr3_-_20227619 0.53 ENST00000425061.1
ENST00000443724.1
ENST00000421451.1
ENST00000452020.1
ENST00000417364.1
ENST00000306698.2
ENST00000419233.2
ENST00000263753.4
ENST00000383774.1
ENST00000437051.1
ENST00000412868.1
ENST00000429446.3
ENST00000442720.1
shugoshin-like 1 (S. pombe)
chr19_-_42758040 0.44 ENST00000593944.1
Ets2 repressor factor
chr2_-_169769787 0.41 ENST00000451987.1
SPC25, NDC80 kinetochore complex component
chr1_-_197115818 0.38 ENST00000367409.4
ENST00000294732.7
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr3_-_129375556 0.37 ENST00000510323.1
transmembrane and coiled-coil domain family 1
chr4_+_113558272 0.35 ENST00000509061.1
ENST00000508577.1
ENST00000513553.1
La ribonucleoprotein domain family, member 7
chr10_+_35416223 0.34 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
cAMP responsive element modulator
chr4_-_13629269 0.34 ENST00000040738.5
biorientation of chromosomes in cell division 1-like 1
chr16_+_21312170 0.31 ENST00000338573.5
ENST00000561968.1
CRYM antisense RNA 1
chr10_+_104614008 0.29 ENST00000369883.3
chromosome 10 open reading frame 32
chr9_-_6015607 0.29 ENST00000259569.5
RAN binding protein 6
chr2_+_196521458 0.29 ENST00000409086.3
solute carrier family 39 (zinc transporter), member 10
chr1_+_145726886 0.28 ENST00000443667.1
PDZ domain containing 1
chr1_-_89458415 0.27 ENST00000321792.5
ENST00000370491.3
RNA binding motif protein, X-linked-like 1
cysteine conjugate-beta lyase 2
chr4_+_52917451 0.27 ENST00000295213.4
ENST00000419395.2
spermatogenesis associated 18
chr7_-_143599207 0.27 ENST00000355951.2
ENST00000479870.1
ENST00000478172.1
family with sequence similarity 115, member A
chr15_-_57025759 0.26 ENST00000267807.7
zinc finger protein 280D
chr10_-_43133950 0.26 ENST00000359467.3
zinc finger protein 33B
chr20_+_30327063 0.26 ENST00000300403.6
ENST00000340513.4
TPX2, microtubule-associated
chr10_-_102046098 0.25 ENST00000441611.1
biogenesis of lysosomal organelles complex-1, subunit 2
chr10_-_102046417 0.25 ENST00000370372.2
biogenesis of lysosomal organelles complex-1, subunit 2
chr19_-_52489923 0.25 ENST00000593596.1
ENST00000243644.4
ENST00000594929.1
ENST00000601430.1
zinc finger protein 350
chr6_-_73935163 0.25 ENST00000370388.3
KH homology domain containing 1-like
chr5_+_68485363 0.25 ENST00000283006.2
ENST00000515001.1
centromere protein H
chr17_-_74533963 0.24 ENST00000293230.5
cytoglobin
chr1_+_64014588 0.23 ENST00000371086.2
ENST00000340052.3
deleted in lymphocytic leukemia 2-like
chr1_+_62417957 0.23 ENST00000307297.7
ENST00000543708.1
InaD-like (Drosophila)
chr4_-_89080003 0.23 ENST00000237612.3
ATP-binding cassette, sub-family G (WHITE), member 2
chr19_+_36027660 0.22 ENST00000585510.1
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr13_-_46679185 0.22 ENST00000439329.3
carboxypeptidase B2 (plasma)
chr7_-_50633078 0.22 ENST00000444124.2
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr7_-_102252589 0.22 ENST00000520042.1
RAS p21 protein activator 4
chr7_-_7679633 0.21 ENST00000401447.1
replication protein A3, 14kDa
chr4_+_174818390 0.21 ENST00000509968.1
ENST00000512263.1
RP11-161D15.1
chr5_+_68485433 0.21 ENST00000502689.1
centromere protein H
chr8_+_27631903 0.21 ENST00000305188.8
establishment of sister chromatid cohesion N-acetyltransferase 2
chrX_+_43515467 0.21 ENST00000338702.3
ENST00000542639.1
monoamine oxidase A
chr14_-_70883708 0.21 ENST00000256366.4
synaptojanin 2 binding protein
chr1_-_93645818 0.21 ENST00000370280.1
ENST00000479918.1
transmembrane emp24 protein transport domain containing 5
chr7_+_79764104 0.20 ENST00000351004.3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr10_+_70587279 0.20 ENST00000298596.6
ENST00000399169.4
ENST00000399165.4
ENST00000399162.2
storkhead box 1
chr12_+_69753448 0.20 ENST00000247843.2
ENST00000548020.1
ENST00000549685.1
ENST00000552955.1
YEATS domain containing 4
chr10_-_81708854 0.20 ENST00000372292.3
surfactant protein D
chr17_-_38574169 0.20 ENST00000423485.1
topoisomerase (DNA) II alpha 170kDa
chr12_+_86268065 0.20 ENST00000551529.1
ENST00000256010.6
neurotensin
chrX_+_155110956 0.19 ENST00000286448.6
ENST00000262640.6
ENST00000460621.1
vesicle-associated membrane protein 7
chr1_-_150207017 0.19 ENST00000369119.3
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr19_-_38878632 0.19 ENST00000586599.1
ENST00000334928.6
ENST00000587676.1
gametogenetin
chr13_+_37581115 0.19 ENST00000481013.1
exosome component 8
chr17_+_28705921 0.18 ENST00000225719.4
carboxypeptidase D
chr8_+_120428546 0.18 ENST00000259526.3
nephroblastoma overexpressed
chr6_+_63921351 0.18 ENST00000370659.1
FK506 binding protein 1C
chr2_+_196521903 0.18 ENST00000541054.1
solute carrier family 39 (zinc transporter), member 10
chr16_+_53412368 0.18 ENST00000565189.1
RP11-44F14.2
chr1_-_89458287 0.18 ENST00000370485.2
cysteine conjugate-beta lyase 2
chr12_+_85430110 0.18 ENST00000393212.3
ENST00000393217.2
leucine-rich repeats and IQ motif containing 1
chr8_+_104310661 0.18 ENST00000522566.1
frizzled family receptor 6
chr4_-_113558014 0.17 ENST00000503172.1
ENST00000505019.1
ENST00000309071.5
chromosome 4 open reading frame 21
chr20_-_52612705 0.17 ENST00000434986.2
breast carcinoma amplified sequence 1
chr4_-_105416039 0.17 ENST00000394767.2
CXXC finger protein 4
chr3_+_3168600 0.17 ENST00000251607.6
ENST00000339437.6
ENST00000280591.6
ENST00000420393.1
tRNA nucleotidyl transferase, CCA-adding, 1
chr3_-_20227720 0.17 ENST00000412997.1
shugoshin-like 1 (S. pombe)
chr6_+_125524785 0.17 ENST00000392482.2
tumor protein D52-like 1
chr6_-_18249971 0.17 ENST00000507591.1
DEK oncogene
chrX_+_21857717 0.17 ENST00000379484.5
membrane-bound transcription factor peptidase, site 2
chr5_+_68860949 0.17 ENST00000507595.1
general transcription factor IIH, polypeptide 2C
chr2_+_33701684 0.17 ENST00000442390.1
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr12_-_71533055 0.17 ENST00000552128.1
tetraspanin 8
chr1_+_214776516 0.16 ENST00000366955.3
centromere protein F, 350/400kDa
chr1_+_111888890 0.16 ENST00000369738.4
primary cilia formation
chr11_+_22646739 0.16 ENST00000428556.2
AC103801.2
chr17_-_7590745 0.16 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
tumor protein p53
chr3_-_165555200 0.16 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
butyrylcholinesterase
chr5_+_42756903 0.16 ENST00000361970.5
ENST00000388827.4
coiled-coil domain containing 152
chr1_+_155583012 0.16 ENST00000462250.2
misato 1, mitochondrial distribution and morphology regulator
chr1_-_38157877 0.16 ENST00000477060.1
ENST00000491981.1
ENST00000488137.1
chromosome 1 open reading frame 109
chr10_-_70092671 0.16 ENST00000358769.2
ENST00000432941.1
ENST00000495025.2
phenazine biosynthesis-like protein domain containing
chr1_-_94344686 0.16 ENST00000528680.1
deoxynucleotidyltransferase, terminal, interacting protein 2
chr19_+_36705504 0.16 ENST00000456324.1
zinc finger protein 146
chr15_-_41624685 0.16 ENST00000560640.1
ENST00000220514.3
Opa interacting protein 5
chr1_-_26232522 0.16 ENST00000399728.1
stathmin 1
chr12_-_50419177 0.16 ENST00000454520.2
ENST00000546595.1
ENST00000548824.1
ENST00000549777.1
ENST00000546723.1
ENST00000427314.2
ENST00000552157.1
ENST00000552310.1
ENST00000548644.1
ENST00000312377.5
ENST00000546786.1
ENST00000550149.1
ENST00000546764.1
ENST00000552004.1
ENST00000548320.1
ENST00000547905.1
ENST00000550651.1
ENST00000551145.1
ENST00000434422.1
ENST00000552921.1
Rac GTPase activating protein 1
chr11_+_17281900 0.16 ENST00000530527.1
nucleobindin 2
chr6_-_26285737 0.16 ENST00000377727.1
ENST00000289352.1
histone cluster 1, H4h
chr7_-_91509972 0.15 ENST00000425936.1
mitochondrial transcription termination factor
chr1_-_146696901 0.15 ENST00000369272.3
ENST00000441068.2
flavin containing monooxygenase 5
chr8_+_38089198 0.15 ENST00000528358.1
ENST00000529642.1
ENST00000532222.1
ENST00000520272.2
DDHD domain containing 2
chr1_+_93646238 0.15 ENST00000448243.1
ENST00000370276.1
coiled-coil domain containing 18
chr9_+_99212403 0.15 ENST00000375251.3
ENST00000375249.4
hyaluronan binding protein 4
chr4_+_76871883 0.15 ENST00000599764.1
Uncharacterized protein
chr6_+_26538566 0.15 ENST00000377575.2
high mobility group nucleosomal binding domain 4
chrX_+_100353153 0.15 ENST00000423383.1
ENST00000218507.5
ENST00000403304.2
ENST00000435570.1
centromere protein I
chr1_+_196788887 0.15 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
complement factor H-related 1
complement factor H-related 2
chr5_+_111496631 0.15 ENST00000508590.1
EPB41L4A antisense RNA 1
chr15_-_45670924 0.15 ENST00000396659.3
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr10_-_102045882 0.15 ENST00000579542.1
biogenesis of lysosomal organelles complex-1, subunit 2
chr3_-_149093499 0.15 ENST00000472441.1
transmembrane 4 L six family member 1
chr2_+_196521845 0.15 ENST00000359634.5
ENST00000412905.1
solute carrier family 39 (zinc transporter), member 10
chr19_+_40502938 0.15 ENST00000599504.1
ENST00000596894.1
ENST00000601138.1
ENST00000600094.1
ENST00000347077.4
zinc finger protein 546
chr3_+_160394940 0.15 ENST00000320767.2
ADP-ribosylation factor-like 14
chr22_-_36013368 0.14 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
myoglobin
chr14_+_104177607 0.14 ENST00000429169.1
Uncharacterized protein; cDNA FLJ53535
chr9_-_77567743 0.14 ENST00000376854.5
chromosome 9 open reading frame 40
chr7_-_35840198 0.14 ENST00000412856.1
ENST00000437235.3
ENST00000424194.1
AC007551.3
chr3_-_57233966 0.14 ENST00000473921.1
ENST00000295934.3
HESX homeobox 1
chr4_-_104119528 0.14 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
centromere protein E, 312kDa
chr10_-_5227096 0.14 ENST00000488756.1
ENST00000334314.3
aldo-keto reductase family 1, member C-like 1
chr7_-_35077653 0.14 ENST00000310974.4
dpy-19-like 1 (C. elegans)
chr3_-_50336548 0.14 ENST00000450489.1
ENST00000513170.1
ENST00000450982.1
N-acetyltransferase 6 (GCN5-related)
hyaluronoglucosaminidase 3
chr6_+_122720681 0.14 ENST00000368455.4
ENST00000452194.1
heat shock transcription factor 2
chr2_+_205410723 0.14 ENST00000358768.2
ENST00000351153.1
ENST00000349953.3
par-3 family cell polarity regulator beta
chr7_-_102789629 0.13 ENST00000417955.1
ENST00000341533.4
ENST00000425379.1
N-acyl phosphatidylethanolamine phospholipase D
chr6_-_28321971 0.13 ENST00000396838.2
ENST00000426434.1
ENST00000434036.1
ENST00000439628.1
zinc finger and SCAN domain containing 31
chr12_+_10658489 0.13 ENST00000538173.1
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr9_+_116343192 0.13 ENST00000471324.2
regulator of G-protein signaling 3
chr3_-_187455680 0.13 ENST00000438077.1
B-cell CLL/lymphoma 6
chr19_-_4540486 0.13 ENST00000306390.6
leucine-rich alpha-2-glycoprotein 1
chr10_-_36812323 0.13 ENST00000543053.1
nicotinamide phosphoribosyltransferase-like
chr2_-_152589670 0.13 ENST00000604864.1
ENST00000603639.1
nebulin
chr17_-_61523622 0.13 ENST00000448884.2
ENST00000582297.1
ENST00000582034.1
ENST00000578072.1
ENST00000360793.3
cytochrome b561
chr8_-_74206673 0.13 ENST00000396465.1
ribosomal protein L7
chr11_+_86667117 0.13 ENST00000531827.1
RP11-736K20.6
chr15_+_49170083 0.13 ENST00000530028.2
EP300 interacting inhibitor of differentiation 1
chr11_-_506316 0.12 ENST00000532055.1
ENST00000531540.1
ribonuclease/angiogenin inhibitor 1
chr14_-_39639523 0.12 ENST00000330149.5
ENST00000554018.1
ENST00000347691.5
trafficking protein particle complex 6B
chr19_+_54372877 0.12 ENST00000414489.1
myeloid-associated differentiation marker
chr6_-_47009996 0.12 ENST00000371243.2
G protein-coupled receptor 110
chr22_-_41985865 0.12 ENST00000216259.7
phosphomannomutase 1
chr4_+_113558612 0.12 ENST00000505034.1
ENST00000324052.6
La ribonucleoprotein domain family, member 7
chr17_-_46178741 0.12 ENST00000581003.1
ENST00000225603.4
chromobox homolog 1
chr7_+_102389434 0.12 ENST00000409231.3
ENST00000418198.1
family with sequence similarity 185, member A
chrX_+_57618269 0.12 ENST00000374888.1
zinc finger, X-linked, duplicated B
chr2_-_3523507 0.12 ENST00000327435.6
acireductone dioxygenase 1
chr14_-_36789783 0.12 ENST00000605579.1
ENST00000604336.1
ENST00000359527.7
ENST00000603139.1
ENST00000318473.7
MAP3K12 binding inhibitory protein 1
chr12_+_62860581 0.12 ENST00000393632.2
ENST00000393630.3
ENST00000280379.6
ENST00000546600.1
ENST00000552738.1
ENST00000393629.2
ENST00000552115.1
MON2 homolog (S. cerevisiae)
chr20_-_4229721 0.12 ENST00000379453.4
adrenoceptor alpha 1D
chr2_-_70475701 0.12 ENST00000282574.4
TIA1 cytotoxic granule-associated RNA binding protein
chr17_+_42219267 0.12 ENST00000319977.4
ENST00000585683.1
chromosome 17 open reading frame 53
chr1_+_111991474 0.11 ENST00000369722.3
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
chr1_-_169455169 0.11 ENST00000367804.4
ENST00000236137.5
solute carrier family 19 (thiamine transporter), member 2
chr11_-_33774944 0.11 ENST00000532057.1
ENST00000531080.1
F-box protein 3
chr19_+_58341656 0.11 ENST00000442832.4
ENST00000594901.1
zinc finger protein 587B
chr5_-_34008130 0.11 ENST00000382085.3
ENST00000512079.1
ENST00000382068.3
ENST00000382072.2
alpha-methylacyl-CoA racemase
chr4_-_169931393 0.11 ENST00000504480.1
ENST00000306193.3
carbonyl reductase 4
chr17_+_42219383 0.11 ENST00000245382.6
chromosome 17 open reading frame 53
chr4_-_100871506 0.11 ENST00000296417.5
H2A histone family, member Z
chr3_-_52804872 0.11 ENST00000535191.1
ENST00000461689.1
ENST00000383721.4
ENST00000233027.5
NIMA-related kinase 4
chr2_-_70189397 0.11 ENST00000320256.4
aspartic peptidase, retroviral-like 1
chr8_-_66546373 0.11 ENST00000518908.1
ENST00000458464.2
ENST00000519352.1
armadillo repeat containing 1
chr11_+_111957497 0.11 ENST00000375549.3
ENST00000528182.1
ENST00000528048.1
ENST00000528021.1
ENST00000526592.1
ENST00000525291.1
succinate dehydrogenase complex, subunit D, integral membrane protein
chr14_-_23284703 0.11 ENST00000555911.1
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr18_+_21033239 0.11 ENST00000581585.1
ENST00000577501.1
RIO kinase 3
chr9_+_139871948 0.11 ENST00000224167.2
ENST00000457950.1
ENST00000371625.3
ENST00000371623.3
prostaglandin D2 synthase 21kDa (brain)
chr2_-_201753717 0.11 ENST00000409264.2
peptidylprolyl isomerase (cyclophilin)-like 3
chr13_+_100153665 0.11 ENST00000376387.4
transmembrane 9 superfamily member 2
chr7_-_38948774 0.11 ENST00000395969.2
ENST00000414632.1
ENST00000310301.4
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr8_+_95835438 0.11 ENST00000521860.1
ENST00000519457.1
ENST00000519053.1
ENST00000523731.1
ENST00000447247.1
integrator complex subunit 8
chr15_-_35280426 0.11 ENST00000559564.1
ENST00000356321.4
zinc finger protein 770
chr15_+_75074410 0.11 ENST00000439220.2
c-src tyrosine kinase
chr18_+_51795774 0.11 ENST00000579534.1
ENST00000406285.3
ENST00000577612.1
ENST00000579434.1
ENST00000583136.1
polymerase (DNA directed) iota
chr11_+_43702236 0.11 ENST00000531185.1
ENST00000278353.4
hydroxysteroid (17-beta) dehydrogenase 12
chr12_-_8088773 0.11 ENST00000544291.1
solute carrier family 2 (facilitated glucose transporter), member 3
chr8_+_22224811 0.11 ENST00000381237.1
solute carrier family 39 (zinc transporter), member 14
chr15_+_90118723 0.11 ENST00000560985.1
TOPBP1-interacting checkpoint and replication regulator
chr1_-_207226313 0.11 ENST00000367084.1
YOD1 deubiquitinase
chr5_+_271733 0.11 ENST00000264933.4
programmed cell death 6
chr2_-_55496344 0.11 ENST00000403721.1
ENST00000263629.4
mitochondrial translational initiation factor 2
chr12_+_19592602 0.11 ENST00000398864.3
ENST00000266508.9
AE binding protein 2
chr14_+_39734482 0.11 ENST00000554392.1
ENST00000555716.1
ENST00000341749.3
ENST00000557038.1
CTAGE family, member 5
chr11_+_61159832 0.11 ENST00000334888.5
ENST00000398979.3
transmembrane protein 216
chr8_+_17780346 0.11 ENST00000325083.8
pericentriolar material 1
chr16_+_81040103 0.11 ENST00000305850.5
ENST00000299572.5
centromere protein N
chr12_-_88535747 0.10 ENST00000309041.7
centrosomal protein 290kDa
chr8_-_17579726 0.10 ENST00000381861.3
microtubule associated tumor suppressor 1
chr16_-_18923035 0.10 ENST00000563836.1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr20_-_8000426 0.10 ENST00000527925.1
ENST00000246024.2
thioredoxin-related transmembrane protein 4
chr1_+_93297622 0.10 ENST00000315741.5
ribosomal protein L5
chr9_+_131037623 0.10 ENST00000495313.1
ENST00000372898.2
SWI5 recombination repair homolog (yeast)
chr17_-_2415169 0.10 ENST00000263092.6
ENST00000538844.1
ENST00000576976.1
methyltransferase like 16
chr1_+_111889212 0.10 ENST00000369737.4
primary cilia formation
chr2_-_70475586 0.10 ENST00000416149.2
TIA1 cytotoxic granule-associated RNA binding protein
chr8_-_74206133 0.10 ENST00000352983.2
ribosomal protein L7
chr19_+_19144384 0.10 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
armadillo repeat containing 6
chr1_-_21113105 0.10 ENST00000375000.1
ENST00000419490.1
ENST00000414993.1
ENST00000443615.1
ENST00000312239.5
heterochromatin protein 1, binding protein 3
chr6_+_37321748 0.10 ENST00000373479.4
ENST00000394443.4
ring finger protein 8, E3 ubiquitin protein ligase
chr9_-_39239171 0.10 ENST00000358144.2
contactin associated protein-like 3
chr3_-_148804275 0.10 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
helicase-like transcription factor
chr17_+_76311791 0.10 ENST00000586321.1
AC061992.2
chr12_-_11139511 0.10 ENST00000506868.1
taste receptor, type 2, member 50
chr1_+_186798073 0.10 ENST00000367466.3
ENST00000442353.2
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr12_+_100897130 0.10 ENST00000551379.1
ENST00000188403.7
ENST00000551184.1
nuclear receptor subfamily 1, group H, member 4
chr7_-_102789503 0.10 ENST00000465647.1
ENST00000418294.1
N-acyl phosphatidylethanolamine phospholipase D
chr7_+_86781677 0.10 ENST00000331242.7
ENST00000394702.3
ENST00000413276.2
ENST00000446796.2
ENST00000411766.2
ENST00000420131.1
ENST00000414630.2
ENST00000453049.1
ENST00000428819.1
ENST00000448598.1
ENST00000449088.3
ENST00000430405.3
cyclin D binding myb-like transcription factor 1
chr8_+_59323823 0.10 ENST00000399598.2
UBX domain protein 2B
chr6_+_52535878 0.10 ENST00000211314.4
transmembrane protein 14A
chr1_+_202830876 0.10 ENST00000456105.2
RP11-480I12.7
chr17_-_61523535 0.10 ENST00000584031.1
ENST00000392976.1
cytochrome b561
chr7_-_124405681 0.10 ENST00000303921.2
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr16_-_15188106 0.09 ENST00000429751.2
ENST00000564131.1
ENST00000563559.1
ENST00000198767.6
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)

Network of associatons between targets according to the STRING database.

First level regulatory network of HSFY2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0030070 insulin processing(GO:0030070)
0.1 0.4 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.6 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.1 0.3 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) isoquinoline alkaloid metabolic process(GO:0033076)
0.1 0.2 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.1 0.2 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.0 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.2 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.2 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.2 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.1 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.0 0.2 GO:0006601 creatine biosynthetic process(GO:0006601)
0.0 0.6 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.2 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.0 0.2 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.2 GO:1903998 response to isolation stress(GO:0035900) regulation of eating behavior(GO:1903998)
0.0 0.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.8 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.2 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.2 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.4 GO:0071600 otic vesicle morphogenesis(GO:0071600)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.0 0.1 GO:1990927 negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.1 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.1 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.2 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:1901656 cellular response to mycotoxin(GO:0036146) glycoside transport(GO:1901656) cellular response to bile acid(GO:1903413)
0.0 0.1 GO:2000213 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.3 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.2 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.2 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.1 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.2 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.0 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.2 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.2 GO:0071493 cellular response to UV-B(GO:0071493)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.2 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.2 GO:0030638 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.4 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.2 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.1 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.6 GO:0043486 histone exchange(GO:0043486)
0.0 0.1 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
0.0 0.5 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.0 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.0 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.0 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.2 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.0 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.3 GO:0031297 replication fork processing(GO:0031297)
0.0 0.2 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.1 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0 0.0 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.0 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.0 0.0 GO:0048371 lateral mesodermal cell differentiation(GO:0048371) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0090210 vitamin E metabolic process(GO:0042360) regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.0 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 0.4 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.3 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.4 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.1 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.1 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.0 0.1 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.5 GO:0010369 chromocenter(GO:0010369)
0.0 0.0 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.0 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.0 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 0.5 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.3 GO:0043203 axon hillock(GO:0043203)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.2 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.3 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 0.2 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 0.2 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.2 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.1 0.2 GO:0015068 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.1 0.2 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 1.0 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.0 0.2 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 0.2 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.1 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.4 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.2 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 1.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.3 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.1 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.0 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.0 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.0 GO:0019201 guanylate kinase activity(GO:0004385) phosphotransferase activity, phosphate group as acceptor(GO:0016776) nucleotide kinase activity(GO:0019201)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.0 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.0 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.1 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.0 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.2 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha