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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for IKZF2

Z-value: 0.68

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Transcription factors associated with IKZF2

Gene Symbol Gene ID Gene Info
IKZF2
ENSG00000030419.12 IKAROS family zinc finger 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IKZF2hg19_v2_chr2_-_214015111_214015179-0.722.8e-01Click!

Activity profile of IKZF2 motif

Sorted Z-values of IKZF2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_79115503 0.67 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr10_-_10504285 0.56 ENST00000602311.1
RP11-271F18.4
RP11-271F18.4
chr1_+_158979680 0.43 ENST00000368131.4
ENST00000340979.6
IFI16
interferon, gamma-inducible protein 16
chr1_+_158979686 0.43 ENST00000368132.3
ENST00000295809.7
IFI16
interferon, gamma-inducible protein 16
chr6_-_15586238 0.43 ENST00000462989.2
DTNBP1
dystrobrevin binding protein 1
chr8_-_23282820 0.41 ENST00000520871.1
LOXL2
lysyl oxidase-like 2
chr17_-_6915616 0.40 ENST00000575889.1
AC027763.2
Uncharacterized protein
chr3_+_156393349 0.39 ENST00000473702.1
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr15_+_45722727 0.35 ENST00000396650.2
ENST00000558435.1
ENST00000344300.3
C15orf48
chromosome 15 open reading frame 48
chr8_-_123706338 0.35 ENST00000521608.1
RP11-973F15.1
long intergenic non-protein coding RNA 1151
chr12_+_15154767 0.34 ENST00000542689.1
RP11-508P1.2
RP11-508P1.2
chr1_+_158979792 0.33 ENST00000359709.3
ENST00000430894.2
IFI16
interferon, gamma-inducible protein 16
chr17_+_39405939 0.33 ENST00000334109.2
KRTAP9-4
keratin associated protein 9-4
chr11_-_33891362 0.32 ENST00000395833.3
LMO2
LIM domain only 2 (rhombotin-like 1)
chr19_+_50433476 0.30 ENST00000596658.1
ATF5
activating transcription factor 5
chr6_+_126221034 0.30 ENST00000433571.1
NCOA7
nuclear receptor coactivator 7
chr1_-_161337662 0.29 ENST00000367974.1
C1orf192
chromosome 1 open reading frame 192
chr11_+_18417948 0.28 ENST00000542179.1
LDHA
lactate dehydrogenase A
chr13_-_34250861 0.27 ENST00000445227.1
ENST00000454681.2
RP11-141M1.3
RP11-141M1.3
chr13_-_30160925 0.27 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr19_-_39735646 0.26 ENST00000413851.2
IFNL3
interferon, lambda 3
chr2_+_120517717 0.26 ENST00000420482.1
ENST00000488279.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr1_-_57045228 0.26 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr17_-_15469590 0.24 ENST00000312127.2
CDRT1
CMT duplicated region transcript 1; Uncharacterized protein
chr12_-_122240792 0.24 ENST00000545885.1
ENST00000542933.1
ENST00000428029.2
ENST00000541694.1
ENST00000536662.1
ENST00000535643.1
ENST00000541657.1
AC084018.1
RHOF
AC084018.1
ras homolog family member F (in filopodia)
chr6_+_36839616 0.24 ENST00000359359.2
ENST00000510325.2
C6orf89
chromosome 6 open reading frame 89
chr1_-_157014865 0.23 ENST00000361409.2
ARHGEF11
Rho guanine nucleotide exchange factor (GEF) 11
chr1_-_67600639 0.23 ENST00000544837.1
ENST00000603691.1
C1orf141
chromosome 1 open reading frame 141
chr16_+_75033210 0.22 ENST00000566250.1
ENST00000567962.1
ZNRF1
zinc and ring finger 1, E3 ubiquitin protein ligase
chr19_+_10197463 0.22 ENST00000590378.1
ENST00000397881.3
C19orf66
chromosome 19 open reading frame 66
chr3_-_52931557 0.21 ENST00000504329.1
ENST00000355083.5
TMEM110-MUSTN1
TMEM110
TMEM110-MUSTN1 readthrough
transmembrane protein 110
chr3_+_171844762 0.20 ENST00000443501.1
FNDC3B
fibronectin type III domain containing 3B
chr7_-_127671674 0.20 ENST00000478726.1
LRRC4
leucine rich repeat containing 4
chr17_+_77019030 0.20 ENST00000580454.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr5_+_140180635 0.20 ENST00000522353.2
ENST00000532566.2
PCDHA3
protocadherin alpha 3
chr22_+_43011247 0.20 ENST00000602478.1
RNU12
RNA, U12 small nuclear
chr11_+_58938903 0.20 ENST00000532982.1
DTX4
deltex homolog 4 (Drosophila)
chr17_+_77018896 0.19 ENST00000578229.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr2_-_127963343 0.19 ENST00000335247.7
CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr12_-_8693539 0.19 ENST00000299663.3
CLEC4E
C-type lectin domain family 4, member E
chr14_+_35591020 0.19 ENST00000603611.1
KIAA0391
KIAA0391
chr12_-_8693469 0.18 ENST00000545274.1
ENST00000446457.2
CLEC4E
C-type lectin domain family 4, member E
chr17_-_39093672 0.18 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr20_+_58179582 0.18 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr11_+_126153001 0.18 ENST00000392678.3
ENST00000392680.2
TIRAP
toll-interleukin 1 receptor (TIR) domain containing adaptor protein
chr22_-_39640756 0.18 ENST00000331163.6
PDGFB
platelet-derived growth factor beta polypeptide
chr7_+_66800928 0.18 ENST00000430244.1
RP11-166O4.5
RP11-166O4.5
chr17_+_35294075 0.17 ENST00000254457.5
LHX1
LIM homeobox 1
chr11_+_18417813 0.17 ENST00000540430.1
ENST00000379412.5
LDHA
lactate dehydrogenase A
chrX_+_135252050 0.17 ENST00000449474.1
ENST00000345434.3
FHL1
four and a half LIM domains 1
chr3_-_121740969 0.17 ENST00000393631.1
ENST00000273691.3
ENST00000344209.5
ILDR1
immunoglobulin-like domain containing receptor 1
chr10_+_97759848 0.17 ENST00000424464.1
ENST00000410012.2
ENST00000344386.3
CC2D2B
coiled-coil and C2 domain containing 2B
chr5_+_34685805 0.16 ENST00000508315.1
RAI14
retinoic acid induced 14
chr6_+_149539053 0.16 ENST00000451095.1
RP1-111D6.3
RP1-111D6.3
chr9_-_16705069 0.16 ENST00000471301.2
BNC2
basonuclin 2
chr12_+_9144626 0.16 ENST00000543895.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr1_+_104615595 0.16 ENST00000418362.1
RP11-364B6.1
RP11-364B6.1
chr10_+_115511434 0.16 ENST00000369312.4
PLEKHS1
pleckstrin homology domain containing, family S member 1
chr7_-_127672146 0.16 ENST00000476782.1
LRRC4
leucine rich repeat containing 4
chr3_-_178865747 0.16 ENST00000435560.1
RP11-360P21.2
RP11-360P21.2
chr1_-_47655686 0.16 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr2_+_33661382 0.15 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr2_-_73520667 0.15 ENST00000545030.1
ENST00000436467.2
EGR4
early growth response 4
chr6_-_133055896 0.15 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3
vanin 3
chr12_-_26278030 0.15 ENST00000242728.4
BHLHE41
basic helix-loop-helix family, member e41
chrX_+_135251835 0.15 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr14_+_91709279 0.15 ENST00000554096.1
CTD-2547L24.3
HCG1816139; Uncharacterized protein
chr12_-_104443890 0.15 ENST00000547583.1
ENST00000360814.4
ENST00000546851.1
GLT8D2
glycosyltransferase 8 domain containing 2
chr14_+_35591928 0.15 ENST00000605870.1
ENST00000557404.3
KIAA0391
KIAA0391
chr11_+_47293795 0.15 ENST00000422579.1
MADD
MAP-kinase activating death domain
chr14_+_23025534 0.15 ENST00000557595.1
AE000662.92
Uncharacterized protein
chr2_-_190927447 0.15 ENST00000260950.4
MSTN
myostatin
chr14_+_63671105 0.15 ENST00000316754.3
RHOJ
ras homolog family member J
chrX_+_135251783 0.15 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr4_-_185303418 0.14 ENST00000610223.1
ENST00000608785.1
RP11-290F5.1
RP11-290F5.1
chr6_+_144665237 0.14 ENST00000421035.2
UTRN
utrophin
chr11_+_125464758 0.14 ENST00000529886.1
STT3A
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr7_+_93551011 0.14 ENST00000248564.5
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr22_-_36220420 0.14 ENST00000473487.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chrX_+_135230712 0.14 ENST00000535737.1
FHL1
four and a half LIM domains 1
chr15_-_55541227 0.13 ENST00000566877.1
RAB27A
RAB27A, member RAS oncogene family
chr8_-_36636676 0.13 ENST00000524132.1
ENST00000519451.1
RP11-962G15.1
RP11-962G15.1
chr13_+_49551020 0.13 ENST00000541916.1
FNDC3A
fibronectin type III domain containing 3A
chr14_+_35591735 0.12 ENST00000604948.1
ENST00000605201.1
ENST00000250377.7
ENST00000321130.10
ENST00000534898.4
KIAA0391
KIAA0391
chr8_+_97597148 0.12 ENST00000521590.1
SDC2
syndecan 2
chr4_-_134070250 0.12 ENST00000505289.1
ENST00000509715.1
RP11-9G1.3
RP11-9G1.3
chr11_-_46142948 0.12 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr20_+_42574317 0.12 ENST00000358131.5
TOX2
TOX high mobility group box family member 2
chr15_-_82338460 0.12 ENST00000558133.1
ENST00000329713.4
MEX3B
mex-3 RNA binding family member B
chr19_+_18451391 0.12 ENST00000269919.6
ENST00000604499.2
ENST00000595066.1
ENST00000252813.5
PGPEP1
pyroglutamyl-peptidase I
chr14_-_36988882 0.12 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr14_+_35591858 0.12 ENST00000603544.1
KIAA0391
KIAA0391
chr15_-_59665062 0.11 ENST00000288235.4
MYO1E
myosin IE
chr11_-_19263145 0.11 ENST00000532666.1
ENST00000527884.1
E2F8
E2F transcription factor 8
chr9_+_19049372 0.11 ENST00000380527.1
RRAGA
Ras-related GTP binding A
chr15_+_66679155 0.11 ENST00000307102.5
MAP2K1
mitogen-activated protein kinase kinase 1
chr2_+_101437487 0.11 ENST00000427413.1
ENST00000542504.1
NPAS2
neuronal PAS domain protein 2
chr17_+_57970469 0.11 ENST00000443572.2
ENST00000406116.3
ENST00000225577.4
ENST00000393021.3
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr1_+_230193521 0.11 ENST00000543760.1
GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr13_-_46756351 0.11 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chrX_-_15683147 0.11 ENST00000380342.3
TMEM27
transmembrane protein 27
chr1_-_242612726 0.11 ENST00000459864.1
PLD5
phospholipase D family, member 5
chr8_-_128231299 0.11 ENST00000500112.1
CCAT1
colon cancer associated transcript 1 (non-protein coding)
chr4_+_74347400 0.11 ENST00000226355.3
AFM
afamin
chr3_-_169487617 0.10 ENST00000330368.2
ACTRT3
actin-related protein T3
chr18_-_48351743 0.10 ENST00000588444.1
ENST00000256425.2
ENST00000428869.2
MRO
maestro
chr3_-_71294304 0.10 ENST00000498215.1
FOXP1
forkhead box P1
chr6_-_133055815 0.10 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3
vanin 3
chr22_-_50699701 0.10 ENST00000395780.1
MAPK12
mitogen-activated protein kinase 12
chr17_-_39211463 0.10 ENST00000542910.1
ENST00000398477.1
KRTAP2-2
keratin associated protein 2-2
chr17_-_56082455 0.10 ENST00000578794.1
RP11-159D12.5
Uncharacterized protein
chr4_-_120243545 0.10 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr19_-_51141196 0.10 ENST00000338916.4
SYT3
synaptotagmin III
chr8_+_39770803 0.10 ENST00000518237.1
IDO1
indoleamine 2,3-dioxygenase 1
chr4_-_71532601 0.10 ENST00000510614.1
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr14_-_35591156 0.10 ENST00000554361.1
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr6_+_106534192 0.10 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr6_-_112081113 0.10 ENST00000517419.1
FYN
FYN oncogene related to SRC, FGR, YES
chr1_-_157015162 0.10 ENST00000368194.3
ARHGEF11
Rho guanine nucleotide exchange factor (GEF) 11
chr10_+_121578211 0.09 ENST00000369080.3
INPP5F
inositol polyphosphate-5-phosphatase F
chr17_+_55055466 0.09 ENST00000262288.3
ENST00000572710.1
ENST00000575395.1
SCPEP1
serine carboxypeptidase 1
chr5_-_160973649 0.09 ENST00000393959.1
ENST00000517547.1
GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr2_-_101767715 0.09 ENST00000376840.4
ENST00000409318.1
TBC1D8
TBC1 domain family, member 8 (with GRAM domain)
chr22_+_46449674 0.09 ENST00000381051.2
FLJ27365
hsa-mir-4763
chr1_+_36038971 0.09 ENST00000373235.3
TFAP2E
transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
chr6_-_11779014 0.09 ENST00000229583.5
ADTRP
androgen-dependent TFPI-regulating protein
chr17_+_27047244 0.09 ENST00000394938.4
ENST00000394935.3
ENST00000355731.4
RPL23A
ribosomal protein L23a
chr6_-_11779403 0.09 ENST00000414691.3
ADTRP
androgen-dependent TFPI-regulating protein
chr4_+_26322185 0.08 ENST00000361572.6
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr6_-_11779174 0.08 ENST00000379413.2
ADTRP
androgen-dependent TFPI-regulating protein
chr1_+_112938803 0.08 ENST00000271277.6
CTTNBP2NL
CTTNBP2 N-terminal like
chr1_+_9711781 0.08 ENST00000536656.1
ENST00000377346.4
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
chr6_+_116691001 0.08 ENST00000537543.1
DSE
dermatan sulfate epimerase
chr6_+_32944119 0.08 ENST00000606059.1
BRD2
bromodomain containing 2
chrX_-_15619076 0.08 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr3_+_57882061 0.08 ENST00000461354.1
ENST00000466255.1
SLMAP
sarcolemma associated protein
chr16_+_21623958 0.08 ENST00000568826.1
METTL9
methyltransferase like 9
chr6_+_149539767 0.08 ENST00000606202.1
ENST00000536230.1
ENST00000445901.1
TAB2
RP1-111D6.3
TGF-beta activated kinase 1/MAP3K7 binding protein 2
RP1-111D6.3
chrX_+_48660287 0.08 ENST00000444343.2
ENST00000376610.2
ENST00000334136.5
ENST00000376619.2
HDAC6
histone deacetylase 6
chr8_-_102987548 0.08 ENST00000520690.1
NCALD
neurocalcin delta
chr12_-_80328905 0.08 ENST00000547330.1
PPP1R12A
protein phosphatase 1, regulatory subunit 12A
chr15_-_66679019 0.08 ENST00000568216.1
ENST00000562124.1
ENST00000570251.1
TIPIN
TIMELESS interacting protein
chr17_+_27046988 0.08 ENST00000496182.1
RPL23A
ribosomal protein L23a
chr17_-_48785216 0.08 ENST00000285243.6
ANKRD40
ankyrin repeat domain 40
chr3_-_71632894 0.08 ENST00000493089.1
FOXP1
forkhead box P1
chr6_+_33388013 0.08 ENST00000449372.2
SYNGAP1
synaptic Ras GTPase activating protein 1
chrX_+_48660107 0.08 ENST00000376643.2
HDAC6
histone deacetylase 6
chr17_-_17740325 0.07 ENST00000338854.5
SREBF1
sterol regulatory element binding transcription factor 1
chr17_+_6915730 0.07 ENST00000548577.1
RNASEK
ribonuclease, RNase K
chr16_-_73093597 0.07 ENST00000397992.5
ZFHX3
zinc finger homeobox 3
chr4_+_130017268 0.07 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
C4orf33
chromosome 4 open reading frame 33
chr7_-_111424506 0.07 ENST00000450156.1
ENST00000494651.2
DOCK4
dedicator of cytokinesis 4
chr10_-_79398250 0.07 ENST00000286627.5
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr17_-_6915646 0.07 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
AC027763.2
Uncharacterized protein
chr10_-_79789291 0.07 ENST00000372371.3
POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr12_-_118797475 0.07 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3
TAO kinase 3
chr19_-_41859814 0.07 ENST00000221930.5
TGFB1
transforming growth factor, beta 1
chr17_+_7387677 0.07 ENST00000322644.6
POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr9_-_73483926 0.07 ENST00000396283.1
ENST00000361823.5
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr19_+_18496957 0.07 ENST00000252809.3
GDF15
growth differentiation factor 15
chr12_-_49449107 0.07 ENST00000301067.7
KMT2D
lysine (K)-specific methyltransferase 2D
chr9_+_22646189 0.07 ENST00000436786.1
RP11-399D6.2
RP11-399D6.2
chr8_-_82024290 0.07 ENST00000220597.4
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr14_-_45431091 0.07 ENST00000579157.1
ENST00000396128.4
ENST00000556500.1
KLHL28
kelch-like family member 28
chr12_+_103981044 0.07 ENST00000388887.2
STAB2
stabilin 2
chr12_-_118796910 0.07 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr6_-_24721054 0.07 ENST00000378119.4
C6orf62
chromosome 6 open reading frame 62
chr1_+_161719552 0.07 ENST00000367943.4
DUSP12
dual specificity phosphatase 12
chr3_-_38992052 0.07 ENST00000302328.3
ENST00000450244.1
ENST00000444237.2
SCN11A
sodium channel, voltage-gated, type XI, alpha subunit
chr1_+_28995231 0.07 ENST00000373816.1
GMEB1
glucocorticoid modulatory element binding protein 1
chr19_-_31840438 0.07 ENST00000240587.4
TSHZ3
teashirt zinc finger homeobox 3
chr9_+_34989638 0.07 ENST00000453597.3
ENST00000335998.3
ENST00000312316.5
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr10_-_128975273 0.07 ENST00000424811.2
FAM196A
family with sequence similarity 196, member A
chrX_-_30993201 0.07 ENST00000288422.2
ENST00000378932.2
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr10_+_48189612 0.07 ENST00000453919.1
AGAP9
ArfGAP with GTPase domain, ankyrin repeat and PH domain 9
chr4_-_74486347 0.07 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr8_-_19459993 0.06 ENST00000454498.2
ENST00000520003.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr21_+_26934165 0.06 ENST00000456917.1
MIR155HG
MIR155 host gene (non-protein coding)
chr1_-_68698222 0.06 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr7_-_122840015 0.06 ENST00000194130.2
SLC13A1
solute carrier family 13 (sodium/sulfate symporter), member 1
chr1_+_2066387 0.06 ENST00000497183.1
PRKCZ
protein kinase C, zeta
chr18_-_47340297 0.06 ENST00000586485.1
ENST00000587994.1
ENST00000586100.1
ENST00000285093.10
ACAA2
acetyl-CoA acyltransferase 2
chr9_-_91793675 0.06 ENST00000375835.4
ENST00000375830.1
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr9_-_130667592 0.06 ENST00000447681.1
ST6GALNAC6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr16_+_20911722 0.06 ENST00000569023.1
LYRM1
LYR motif containing 1
chr17_-_38928414 0.06 ENST00000335552.4
KRT26
keratin 26
chr8_+_9183618 0.06 ENST00000518619.1
RP11-115J16.1
RP11-115J16.1
chr8_-_145754428 0.06 ENST00000527462.1
ENST00000313465.5
ENST00000524821.1
C8orf82
chromosome 8 open reading frame 82
chr19_+_11200038 0.06 ENST00000558518.1
ENST00000557933.1
ENST00000455727.2
ENST00000535915.1
ENST00000545707.1
ENST00000558013.1
LDLR
low density lipoprotein receptor
chrX_+_45364633 0.06 ENST00000435394.1
ENST00000609127.1
RP11-245M24.1
RP11-245M24.1
chr7_-_149158187 0.06 ENST00000247930.4
ZNF777
zinc finger protein 777
chr9_-_15250114 0.06 ENST00000507993.1
TTC39B
tetratricopeptide repeat domain 39B
chr17_-_57970074 0.06 ENST00000346141.6
TUBD1
tubulin, delta 1
chr17_+_7387919 0.06 ENST00000572844.1
POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr1_-_15850676 0.06 ENST00000440484.1
ENST00000333868.5
CASP9
caspase 9, apoptosis-related cysteine peptidase
chr1_+_172502244 0.06 ENST00000610051.1
SUCO
SUN domain containing ossification factor
chr13_+_97874574 0.06 ENST00000343600.4
ENST00000345429.6
ENST00000376673.3
MBNL2
muscleblind-like splicing regulator 2
chr12_+_53835425 0.06 ENST00000549924.1
PRR13
proline rich 13
chr3_+_46618727 0.06 ENST00000296145.5
TDGF1
teratocarcinoma-derived growth factor 1
chr19_+_7599128 0.06 ENST00000545201.2
PNPLA6
patatin-like phospholipase domain containing 6

Network of associatons between targets according to the STRING database.

First level regulatory network of IKZF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0018277 protein deamination(GO:0018277)
0.1 0.2 GO:2000338 interleukin-15 production(GO:0032618) chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338) positive regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000340)
0.1 0.2 GO:2000742 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.3 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.4 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.2 GO:1990936 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0 0.1 GO:0001172 transcription, RNA-templated(GO:0001172)
0.0 0.2 GO:0070843 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.0 GO:1903980 positive regulation of microglial cell activation(GO:1903980)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.5 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.1 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.0 0.3 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.4 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0052255 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.0 0.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:1904235 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.0 0.6 GO:0048569 post-embryonic organ development(GO:0048569)
0.0 0.3 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.1 GO:0061015 snRNA import into nucleus(GO:0061015)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.4 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 1.2 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.0 0.1 GO:1990709 presynaptic active zone organization(GO:1990709)
0.0 0.1 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.1 GO:0060374 mast cell differentiation(GO:0060374)
0.0 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.1 GO:0002035 brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.0 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.1 GO:1903979 negative regulation of microglial cell activation(GO:1903979)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.4 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.0 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555)
0.0 0.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.1 GO:0097101 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) blood vessel endothelial cell fate specification(GO:0097101) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.6 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.1 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.2 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.5 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.1 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.0 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.3 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.2 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.1 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism