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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for IRX3

Z-value: 1.56

Motif logo

Transcription factors associated with IRX3

Gene Symbol Gene ID Gene Info
ENSG00000177508.11 iroquois homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRX3hg19_v2_chr16_-_54320675_54320715-0.643.6e-01Click!

Activity profile of IRX3 motif

Sorted Z-values of IRX3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_150866779 2.05 ENST00000370353.3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr8_-_145060593 1.87 ENST00000313059.5
ENST00000524918.1
ENST00000313028.7
ENST00000525773.1
poly (ADP-ribose) polymerase family, member 10
chr10_+_91092241 1.77 ENST00000371811.4
interferon-induced protein with tetratricopeptide repeats 3
chr7_-_92777606 1.64 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
sterile alpha motif domain containing 9-like
chr1_-_186365908 1.21 ENST00000598663.1
Uncharacterized protein
chr22_-_50970919 1.19 ENST00000329363.4
ENST00000437588.1
outer dense fiber of sperm tails 3B
chr17_+_58018269 1.11 ENST00000591035.1
Uncharacterized protein
chr2_-_231090344 1.11 ENST00000540870.1
ENST00000416610.1
SP110 nuclear body protein
chr4_-_75695366 1.09 ENST00000512743.1
betacellulin
chr11_-_104905840 1.04 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr3_-_49851313 0.96 ENST00000333486.3
ubiquitin-like modifier activating enzyme 7
chr1_+_158979686 0.93 ENST00000368132.3
ENST00000295809.7
interferon, gamma-inducible protein 16
chr14_-_67878917 0.93 ENST00000216446.4
pleckstrin 2
chr17_-_34207295 0.86 ENST00000463941.1
ENST00000293272.3
chemokine (C-C motif) ligand 5
chr12_+_2912363 0.85 ENST00000544366.1
FK506 binding protein 4, 59kDa
chr12_+_75874460 0.85 ENST00000266659.3
GLI pathogenesis-related 1
chr2_+_101591314 0.82 ENST00000450763.1
neuronal PAS domain protein 2
chr21_+_42733870 0.80 ENST00000330714.3
ENST00000436410.1
ENST00000435611.1
myxovirus (influenza virus) resistance 2 (mouse)
chr19_-_38743878 0.75 ENST00000587515.1
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr3_-_122283100 0.72 ENST00000492382.1
ENST00000462315.1
poly (ADP-ribose) polymerase family, member 9
chr9_+_100174232 0.71 ENST00000355295.4
tudor domain containing 7
chr3_+_122399444 0.70 ENST00000474629.2
poly (ADP-ribose) polymerase family, member 14
chr7_-_41742697 0.69 ENST00000242208.4
inhibin, beta A
chr16_-_67224002 0.67 ENST00000563889.1
ENST00000564418.1
ENST00000545725.2
ENST00000314586.6
exocyst complex component 3-like 1
chr11_+_57365150 0.67 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr6_-_32784687 0.65 ENST00000447394.1
ENST00000438763.2
major histocompatibility complex, class II, DO beta
chr1_+_158985457 0.63 ENST00000567661.1
ENST00000474473.1
interferon, gamma-inducible protein 16
chr5_+_135385202 0.63 ENST00000514554.1
transforming growth factor, beta-induced, 68kDa
chr1_-_89488510 0.63 ENST00000564665.1
ENST00000370481.4
guanylate binding protein 3
chr11_-_60010556 0.63 ENST00000427611.2
membrane-spanning 4-domains, subfamily A, member 4E
chr3_-_122283079 0.63 ENST00000471785.1
ENST00000466126.1
poly (ADP-ribose) polymerase family, member 9
chr7_-_33080506 0.62 ENST00000381626.2
ENST00000409467.1
ENST00000449201.1
5'-nucleotidase, cytosolic IIIA
chr2_+_233527443 0.62 ENST00000410095.1
EF-hand domain family, member D1
chr22_-_36556821 0.61 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
apolipoprotein L, 3
chrX_+_78003204 0.60 ENST00000435339.3
ENST00000514744.1
lysophosphatidic acid receptor 4
chr3_-_185270383 0.60 ENST00000296252.4
lipase, member H
chrX_-_77150911 0.58 ENST00000373336.3
magnesium transporter 1
chr3_+_171561127 0.58 ENST00000334567.5
ENST00000450693.1
transmembrane protein 212
chr18_+_21529811 0.58 ENST00000588004.1
laminin, alpha 3
chr7_+_871559 0.57 ENST00000421580.1
Sad1 and UNC84 domain containing 1
chr5_+_175490540 0.57 ENST00000515817.1
family with sequence similarity 153, member B
chr11_-_104480019 0.56 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
chr12_-_10007448 0.56 ENST00000538152.1
C-type lectin domain family 2, member B
chr19_-_54974894 0.55 ENST00000333834.4
leukocyte receptor cluster (LRC) member 9
chr4_+_75480629 0.55 ENST00000380846.3
amphiregulin B
chr11_-_58035732 0.55 ENST00000395079.2
olfactory receptor, family 10, subfamily W, member 1
chr7_+_55086703 0.54 ENST00000455089.1
ENST00000342916.3
ENST00000344576.2
ENST00000420316.2
epidermal growth factor receptor
chr5_-_177207634 0.54 ENST00000513554.1
ENST00000440605.3
family with sequence similarity 153, member A
chr5_-_147211226 0.53 ENST00000296695.5
serine peptidase inhibitor, Kazal type 1
chr2_-_216878305 0.53 ENST00000263268.6
melanoregulin
chr8_-_74495065 0.52 ENST00000523533.1
staufen double-stranded RNA binding protein 2
chr20_+_35504522 0.52 ENST00000602922.1
ENST00000217320.3
TBC/LysM-associated domain containing 2
chr3_+_171844762 0.52 ENST00000443501.1
fibronectin type III domain containing 3B
chr8_+_95731904 0.52 ENST00000522422.1
dpy-19-like 4 (C. elegans)
chr1_+_149239529 0.52 ENST00000457216.2
RP11-403I13.4
chr21_-_43816052 0.52 ENST00000398405.1
transmembrane protease, serine 3
chr18_-_61329118 0.49 ENST00000332821.8
ENST00000283752.5
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr4_+_70894130 0.49 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
histatin 3
chr6_+_126221034 0.48 ENST00000433571.1
nuclear receptor coactivator 7
chr9_+_105757590 0.48 ENST00000374798.3
ENST00000487798.1
cylicin, basic protein of sperm head cytoskeleton 2
chr5_+_169011033 0.48 ENST00000513795.1
spindle apparatus coiled-coil protein 1
chr4_+_71091786 0.47 ENST00000317987.5
follicular dendritic cell secreted protein
chr10_+_35484793 0.46 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
cAMP responsive element modulator
chr11_-_61647935 0.45 ENST00000531956.1
fatty acid desaturase 3
chr1_+_113010056 0.45 ENST00000369686.5
wingless-type MMTV integration site family, member 2B
chrX_-_83757399 0.45 ENST00000373177.2
ENST00000297977.5
ENST00000506585.2
ENST00000449553.2
highly divergent homeobox
chr12_-_123565834 0.44 ENST00000546049.1
phosphatidylinositol transfer protein, membrane-associated 2
chr13_-_46716969 0.44 ENST00000435666.2
lymphocyte cytosolic protein 1 (L-plastin)
chr11_-_46113756 0.44 ENST00000531959.1
PHD finger protein 21A
chr2_+_33661382 0.44 ENST00000402538.3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr19_-_23456996 0.44 ENST00000594653.1
RP11-15H20.7
chr17_-_54893250 0.43 ENST00000397862.2
chromosome 17 open reading frame 67
chr11_-_63330842 0.42 ENST00000255695.1
HRAS-like suppressor 2
chr15_+_67420441 0.42 ENST00000558894.1
SMAD family member 3
chr12_-_49730970 0.42 ENST00000334221.3
complement component 1, q subcomponent-like 4
chr19_+_55591743 0.42 ENST00000588359.1
ENST00000245618.5
EPS8-like 1
chr5_+_34685805 0.42 ENST00000508315.1
retinoic acid induced 14
chr15_+_25200074 0.41 ENST00000390687.4
ENST00000584968.1
ENST00000346403.6
ENST00000554227.2
small nuclear ribonucleoprotein polypeptide N
chr12_+_57984965 0.40 ENST00000540759.2
ENST00000551772.1
ENST00000550465.1
ENST00000354947.5
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr17_-_29641104 0.40 ENST00000577894.1
ENST00000330927.4
ecotropic viral integration site 2B
chr3_+_122283064 0.40 ENST00000296161.4
deltex 3-like (Drosophila)
chr6_-_117747015 0.39 ENST00000368508.3
ENST00000368507.3
c-ros oncogene 1 , receptor tyrosine kinase
chr2_+_58655461 0.39 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
long intergenic non-protein coding RNA 1122
chr4_+_144312659 0.39 ENST00000509992.1
GRB2-associated binding protein 1
chr6_+_26217159 0.39 ENST00000303910.2
histone cluster 1, H2ae
chr19_+_9296279 0.39 ENST00000344248.2
olfactory receptor, family 7, subfamily D, member 2
chr10_+_90660832 0.39 ENST00000371924.1
STAM binding protein-like 1
chr18_+_616672 0.39 ENST00000338387.7
clusterin-like 1 (retinal)
chr4_+_75310851 0.39 ENST00000395748.3
ENST00000264487.2
amphiregulin
chrX_-_140673133 0.39 ENST00000370519.3
sperm protein associated with the nucleus, X-linked, family member A1
chr11_-_65150103 0.39 ENST00000294187.6
ENST00000398802.1
ENST00000360662.3
ENST00000377152.2
ENST00000530936.1
solute carrier family 25, member 45
chr17_+_61086917 0.38 ENST00000424789.2
ENST00000389520.4
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr4_+_185734773 0.38 ENST00000508020.1
Uncharacterized protein
chr14_+_89060739 0.38 ENST00000318308.6
zinc finger CCCH-type containing 14
chr8_+_132952112 0.38 ENST00000520362.1
ENST00000519656.1
EFR3 homolog A (S. cerevisiae)
chr7_-_99680171 0.37 ENST00000428683.1
zinc finger protein 3
chr3_-_185270342 0.37 ENST00000424591.2
lipase, member H
chr22_+_30821732 0.37 ENST00000355143.4
mitochondrial fission process 1
chr6_+_31105426 0.37 ENST00000547221.1
psoriasis susceptibility 1 candidate 1
chr17_-_15469590 0.36 ENST00000312127.2
CMT duplicated region transcript 1; Uncharacterized protein
chr5_-_64064508 0.36 ENST00000513458.4
SREK1-interacting protein 1
chr11_+_71276609 0.36 ENST00000398531.1
ENST00000376536.4
keratin associated protein 5-10
chr4_+_130017268 0.35 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
chromosome 4 open reading frame 33
chr17_-_38978847 0.35 ENST00000269576.5
keratin 10
chr1_-_46598284 0.35 ENST00000423209.1
ENST00000262741.5
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr9_-_4679419 0.35 ENST00000609131.1
ENST00000607997.1
RP11-6J24.6
chr10_+_118349920 0.35 ENST00000531984.1
pancreatic lipase-related protein 1
chr1_-_46598371 0.35 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr17_+_25958174 0.35 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
lectin, galactoside-binding, soluble, 9
chr11_+_114166536 0.34 ENST00000299964.3
nicotinamide N-methyltransferase
chr6_+_71104588 0.34 ENST00000418403.1
RP11-462G2.1
chr1_-_16302608 0.34 ENST00000375743.4
ENST00000375733.2
zinc finger and BTB domain containing 17
chr20_+_44330651 0.33 ENST00000305479.2
WAP four-disulfide core domain 13
chr2_+_228735763 0.33 ENST00000373666.2
dynein assembly factor with WDR repeat domains 1
chrX_+_15767971 0.32 ENST00000479740.1
ENST00000454127.2
carbonic anhydrase VB, mitochondrial
chr7_+_144052381 0.32 ENST00000498580.1
ENST00000056217.5
Rho guanine nucleotide exchange factor (GEF) 5
chr1_-_89641680 0.32 ENST00000294671.2
guanylate binding protein 7
chr11_-_104972158 0.32 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr12_-_91546926 0.32 ENST00000550758.1
decorin
chr4_+_74606223 0.32 ENST00000307407.3
ENST00000401931.1
interleukin 8
chr19_-_59070239 0.32 ENST00000595957.1
ENST00000253023.3
ubiquitin-conjugating enzyme E2M
chr12_-_78934441 0.31 ENST00000546865.1
ENST00000547089.1
RP11-171L9.1
chr1_+_156863470 0.31 ENST00000338302.3
ENST00000455314.1
ENST00000292357.7
platelet endothelial aggregation receptor 1
chrX_-_15683147 0.31 ENST00000380342.3
transmembrane protein 27
chr7_-_45957011 0.31 ENST00000417621.1
insulin-like growth factor binding protein 3
chr11_-_18062872 0.31 ENST00000250018.2
tryptophan hydroxylase 1
chr19_+_16940198 0.30 ENST00000248054.5
ENST00000596802.1
ENST00000379803.1
SIN3 transcription regulator family member B
chr12_-_96794143 0.30 ENST00000543119.2
cyclin-dependent kinase 17
chr4_-_76957214 0.30 ENST00000306621.3
chemokine (C-X-C motif) ligand 11
chr16_+_22518495 0.30 ENST00000541154.1
nuclear pore complex interacting protein family, member B5
chr4_-_70653673 0.29 ENST00000512870.1
sulfotransferase family, cytosolic, 1B, member 1
chr18_-_21166841 0.29 ENST00000269228.5
Niemann-Pick disease, type C1
chr22_+_39966758 0.29 ENST00000407673.1
ENST00000401624.1
ENST00000404898.1
ENST00000402142.3
ENST00000336649.4
ENST00000400164.3
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr3_+_151451707 0.29 ENST00000356517.3
arylacetamide deacetylase-like 2
chr17_+_60447579 0.29 ENST00000450662.2
EF-hand calcium binding domain 3
chr10_-_73497581 0.29 ENST00000398786.2
chromosome 10 open reading frame 105
chr1_-_89591749 0.29 ENST00000370466.3
guanylate binding protein 2, interferon-inducible
chr12_+_93115281 0.28 ENST00000549856.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr2_+_143635222 0.28 ENST00000375773.2
ENST00000409512.1
ENST00000410015.2
kynureninase
chr14_+_95047725 0.28 ENST00000554760.1
ENST00000554866.1
ENST00000329597.7
ENST00000556775.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr1_+_25664408 0.28 ENST00000374358.4
transmembrane protein 50A
chr11_+_4470525 0.28 ENST00000325719.4
olfactory receptor, family 52, subfamily K, member 2
chr10_-_14050522 0.28 ENST00000342409.2
FERM domain containing 4A
chr2_+_231090433 0.28 ENST00000486687.2
ENST00000350136.5
ENST00000392045.3
ENST00000417495.3
ENST00000343805.6
ENST00000420434.3
SP140 nuclear body protein
chr18_+_68002675 0.28 ENST00000584919.1
Uncharacterized protein
chr1_-_150669604 0.28 ENST00000427665.1
ENST00000540514.1
golgi phosphoprotein 3-like
chr1_-_197744763 0.28 ENST00000422998.1
DENN/MADD domain containing 1B
chr6_-_66417107 0.27 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
eyes shut homolog (Drosophila)
chr8_-_56987057 0.27 ENST00000518875.1
ribosomal protein S20
chr11_+_35201826 0.27 ENST00000531873.1
CD44 molecule (Indian blood group)
chr4_+_56212505 0.27 ENST00000505210.1
steroid 5 alpha-reductase 3
chr6_-_88038996 0.27 ENST00000525899.1
gap junction protein, beta 7, 25kDa
chr3_-_124606502 0.27 ENST00000483168.1
integrin, beta 5
chr16_-_25122735 0.27 ENST00000563176.1
RP11-449H11.1
chr3_+_100354442 0.27 ENST00000475887.1
G protein-coupled receptor 128
chr2_+_119699864 0.27 ENST00000541757.1
ENST00000412481.1
macrophage receptor with collagenous structure
chr7_-_122339162 0.27 ENST00000340112.2
ring finger protein 133
chr4_+_26344754 0.27 ENST00000515573.1
recombination signal binding protein for immunoglobulin kappa J region
chr19_-_52531600 0.27 ENST00000356322.6
ENST00000270649.6
zinc finger protein 614
chr12_+_117348742 0.27 ENST00000309909.5
ENST00000455858.2
F-box and WD repeat domain containing 8
chr20_-_33732952 0.26 ENST00000541621.1
ER degradation enhancer, mannosidase alpha-like 2
chr1_+_67632083 0.26 ENST00000347310.5
ENST00000371002.1
interleukin 23 receptor
chr3_+_173116225 0.26 ENST00000457714.1
neuroligin 1
chr5_-_152069089 0.26 ENST00000506723.2
AC091969.1
chr7_-_130597935 0.26 ENST00000447307.1
ENST00000418546.1
microRNA 29a
chr1_-_16302565 0.26 ENST00000537142.1
ENST00000448462.2
zinc finger and BTB domain containing 17
chr12_-_10251603 0.26 ENST00000457018.2
C-type lectin domain family 1, member A
chr17_-_29641084 0.26 ENST00000544462.1
ecotropic viral integration site 2B
chr6_-_112081113 0.25 ENST00000517419.1
FYN oncogene related to SRC, FGR, YES
chr1_-_31902614 0.25 ENST00000596131.1
HCG1787699; Uncharacterized protein
chr14_-_68159152 0.25 ENST00000554035.1
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
chr4_+_69962212 0.25 ENST00000508661.1
UDP glucuronosyltransferase 2 family, polypeptide B7
chr5_-_150138246 0.25 ENST00000518015.1
dynactin 4 (p62)
chr11_+_114310164 0.25 ENST00000544196.1
ENST00000539754.1
ENST00000539275.1
RNA exonuclease 2
chr1_+_1846519 0.25 ENST00000378604.3
calmodulin-like 6
chrX_+_36065053 0.25 ENST00000313548.4
calponin homology domain containing 2
chr8_+_12803176 0.25 ENST00000524591.2
KIAA1456
chr13_-_111522162 0.25 ENST00000538077.1
long intergenic non-protein coding RNA 346
chr6_-_75828774 0.25 ENST00000493109.2
collagen, type XII, alpha 1
chr19_+_20959098 0.25 ENST00000360204.5
ENST00000594534.1
zinc finger protein 66
chr13_+_21714653 0.25 ENST00000382533.4
Sin3A-associated protein, 18kDa
chr16_+_22501658 0.24 ENST00000415833.2
nuclear pore complex interacting protein family, member B5
chr5_+_147443534 0.24 ENST00000398454.1
ENST00000359874.3
ENST00000508733.1
ENST00000256084.7
serine peptidase inhibitor, Kazal type 5
chr2_-_233877912 0.24 ENST00000264051.3
neuronal guanine nucleotide exchange factor
chr13_+_50589390 0.24 ENST00000360473.4
ENST00000312942.1
potassium channel regulator
chr3_+_197677379 0.24 ENST00000442341.1
ribosomal protein L35a
chr12_+_76653611 0.24 ENST00000550380.1
RP11-54A9.1
chr7_-_45956856 0.24 ENST00000428530.1
insulin-like growth factor binding protein 3
chr7_-_99063769 0.24 ENST00000394186.3
ENST00000359832.4
ENST00000449683.1
ENST00000488775.1
ENST00000523680.1
ENST00000292475.3
ENST00000430982.1
ENST00000555673.1
ENST00000413834.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2
pentatricopeptide repeat domain 1
ATP5J2-PTCD1 readthrough
chr6_+_37012607 0.24 ENST00000423336.1
cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2
chr3_-_139195350 0.23 ENST00000232217.2
retinol binding protein 2, cellular
chr1_+_244227632 0.23 ENST00000598000.1
Uncharacterized protein; cDNA FLJ42623 fis, clone BRACE3015894
chr2_+_182850743 0.23 ENST00000409702.1
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr7_+_13141010 0.22 ENST00000443947.1
AC011288.2
chr22_+_51176624 0.22 ENST00000216139.5
ENST00000529621.1
acrosin
chrX_+_52513455 0.22 ENST00000446098.1
X antigen family, member 1C
chr7_+_76090993 0.22 ENST00000425780.1
ENST00000456590.1
ENST00000451769.1
ENST00000324432.5
ENST00000307569.8
ENST00000457529.1
ENST00000446600.1
ENST00000413936.2
ENST00000423646.1
ENST00000438930.1
ENST00000430490.2
deltex homolog 2 (Drosophila)
chr16_+_22524844 0.22 ENST00000538606.1
ENST00000424340.1
ENST00000517539.1
ENST00000528249.1
nuclear pore complex interacting protein family, member B5
chr19_-_38085633 0.22 ENST00000593133.1
ENST00000590751.1
ENST00000358744.3
ENST00000328550.2
ENST00000451802.2
zinc finger protein 571
chr17_+_38673270 0.22 ENST00000578280.1
RP5-1028K7.2

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0010847 regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213)
0.3 1.4 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.3 0.9 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.2 0.7 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.2 0.7 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.2 1.4 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 1.7 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.5 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 0.4 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.1 0.5 GO:0035425 autocrine signaling(GO:0035425)
0.1 1.0 GO:1902571 regulation of serine-type endopeptidase activity(GO:1900003) regulation of serine-type peptidase activity(GO:1902571)
0.1 0.3 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 0.3 GO:0002818 intracellular defense response(GO:0002818)
0.1 1.6 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.3 GO:0006711 estrogen catabolic process(GO:0006711)
0.1 0.4 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 0.4 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536) interleukin-23-mediated signaling pathway(GO:0038155)
0.1 0.3 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 1.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.5 GO:0061107 seminal vesicle development(GO:0061107)
0.1 0.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.3 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.2 GO:0021503 neural fold bending(GO:0021503)
0.1 0.4 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.1 0.3 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 0.3 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.1 0.4 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.2 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.1 0.3 GO:0036509 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.1 0.3 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.6 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.2 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.0 0.4 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.4 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.1 GO:0033504 floor plate development(GO:0033504)
0.0 0.2 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.2 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 1.1 GO:0035810 positive regulation of urine volume(GO:0035810)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.9 GO:0051775 response to redox state(GO:0051775)
0.0 0.8 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.2 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.7 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.4 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.2 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.2 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.5 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.6 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.6 GO:0015693 magnesium ion transport(GO:0015693)
0.0 1.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.8 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.2 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.0 0.6 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.2 GO:1905068 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.2 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 1.5 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.0 0.3 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.2 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.5 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.2 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.9 GO:0006825 copper ion transport(GO:0006825)
0.0 0.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.4 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.8 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:1904219 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.1 GO:2000861 negative regulation of macrophage chemotaxis(GO:0010760) estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.0 0.1 GO:0003051 brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.1 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.1 GO:0035588 purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588) G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.3 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.3 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.1 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.1 GO:0010829 negative regulation of glucose transport(GO:0010829)
0.0 0.4 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.2 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.6 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0032907 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.1 GO:0072564 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.3 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 1.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.7 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.8 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.3 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966) negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.2 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.2 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.4 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.6 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 0.5 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.2 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.0 0.4 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.4 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:1905246 protein retention in Golgi apparatus(GO:0045053) regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.1 GO:1903286 regulation of potassium ion import(GO:1903286)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.2 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.2 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.3 GO:0007097 nuclear migration(GO:0007097)
0.0 0.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.4 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.2 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 0.2 GO:0055075 potassium ion homeostasis(GO:0055075)
0.0 0.0 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.2 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.2 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.3 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.5 GO:0032402 establishment of melanosome localization(GO:0032401) melanosome transport(GO:0032402)
0.0 0.1 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.4 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.1 GO:0030335 positive regulation of cell migration(GO:0030335)
0.0 0.3 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.2 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.2 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.4 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.0 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.1 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.1 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0097179 protease inhibitor complex(GO:0097179)
0.2 0.7 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 0.5 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.2 0.5 GO:0033011 perinuclear theca(GO:0033011)
0.1 0.3 GO:0000806 Y chromosome(GO:0000806)
0.1 0.4 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 0.3 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 0.2 GO:0005595 collagen type XII trimer(GO:0005595)
0.1 0.3 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.1 0.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.5 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.6 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.2 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.2 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.7 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.7 GO:0033391 chromatoid body(GO:0033391)
0.0 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.3 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.2 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.6 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.0 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0019866 organelle inner membrane(GO:0019866)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005549 odorant binding(GO:0005549)
0.2 0.9 GO:0032767 copper-dependent protein binding(GO:0032767)
0.2 0.9 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.2 0.5 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.1 0.7 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.5 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.6 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.3 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.5 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.3 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 0.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.3 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.3 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.1 0.4 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1 3.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.3 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 0.7 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.2 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 1.4 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.4 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.4 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.2 GO:0004040 amidase activity(GO:0004040)
0.1 0.4 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.6 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 0.5 GO:0032190 acrosin binding(GO:0032190)
0.0 0.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0004513 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.0 0.3 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.2 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 0.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.6 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.2 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.2 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 1.0 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 1.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.1 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.6 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 2.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.3 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.0 GO:0016992 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.4 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.5 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.0 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.9 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.3 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.8 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.8 PID AURORA A PATHWAY Aurora A signaling
0.0 0.3 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.4 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.8 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 1.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 2.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.2 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.8 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.8 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions