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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for ISL2

Z-value: 0.85

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Transcription factors associated with ISL2

Gene Symbol Gene ID Gene Info
ISL2
ENSG00000159556.5 ISL LIM homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ISL2hg19_v2_chr15_+_76629064_766290730.963.7e-02Click!

Activity profile of ISL2 motif

Sorted Z-values of ISL2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_327537 1.30 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr4_+_169013666 0.96 ENST00000359299.3
ANXA10
annexin A10
chr19_-_3557570 0.78 ENST00000355415.2
MFSD12
major facilitator superfamily domain containing 12
chr5_-_139726181 0.67 ENST00000507104.1
ENST00000230990.6
HBEGF
heparin-binding EGF-like growth factor
chr14_-_67878917 0.67 ENST00000216446.4
PLEK2
pleckstrin 2
chr12_-_58212487 0.57 ENST00000549994.1
AVIL
advillin
chr15_+_90735145 0.57 ENST00000559792.1
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr12_+_14369524 0.55 ENST00000538329.1
RP11-134N1.2
RP11-134N1.2
chr10_-_128359074 0.55 ENST00000544758.1
C10orf90
chromosome 10 open reading frame 90
chr10_+_35484793 0.53 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr9_-_100854838 0.49 ENST00000538344.1
TRIM14
tripartite motif containing 14
chr1_+_152178320 0.49 ENST00000429352.1
RP11-107M16.2
RP11-107M16.2
chr1_-_190446759 0.45 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr4_-_120243545 0.42 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr6_+_151561085 0.41 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr5_-_173217931 0.40 ENST00000522731.1
CTB-43E15.4
CTB-43E15.4
chr19_+_4402659 0.39 ENST00000301280.5
ENST00000585854.1
CHAF1A
chromatin assembly factor 1, subunit A (p150)
chr2_-_231860596 0.38 ENST00000441063.1
ENST00000434094.1
ENST00000418330.1
ENST00000457803.1
ENST00000414876.1
ENST00000446741.1
ENST00000426904.1
AC105344.2
SPATA3 antisense RNA 1 (head to head)
chr2_-_87248975 0.37 ENST00000409310.2
ENST00000355705.3
PLGLB1
plasminogen-like B1
chr14_-_73997901 0.36 ENST00000557603.1
ENST00000556455.1
HEATR4
HEAT repeat containing 4
chr12_+_64798826 0.36 ENST00000540203.1
XPOT
exportin, tRNA
chr13_+_78315348 0.35 ENST00000441784.1
SLAIN1
SLAIN motif family, member 1
chr1_+_151253991 0.35 ENST00000443959.1
ZNF687
zinc finger protein 687
chr1_-_228613026 0.35 ENST00000366696.1
HIST3H3
histone cluster 3, H3
chr12_-_51422017 0.34 ENST00000394904.3
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr2_+_234826016 0.34 ENST00000324695.4
ENST00000433712.2
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr3_-_141747950 0.32 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr4_-_90756769 0.31 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr11_-_107729287 0.31 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr11_-_74800799 0.31 ENST00000305159.3
OR2AT4
olfactory receptor, family 2, subfamily AT, member 4
chr4_-_19458597 0.30 ENST00000505347.1
RP11-3J1.1
RP11-3J1.1
chr12_+_75784850 0.30 ENST00000550916.1
ENST00000435775.1
ENST00000378689.2
ENST00000378692.3
ENST00000320460.4
ENST00000547164.1
GLIPR1L2
GLI pathogenesis-related 1 like 2
chrX_-_55208866 0.28 ENST00000545075.1
MTRNR2L10
MT-RNR2-like 10
chr2_-_136633940 0.27 ENST00000264156.2
MCM6
minichromosome maintenance complex component 6
chr10_-_95241951 0.27 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
MYOF
myoferlin
chr3_-_121740969 0.27 ENST00000393631.1
ENST00000273691.3
ENST00000344209.5
ILDR1
immunoglobulin-like domain containing receptor 1
chr12_-_118628315 0.26 ENST00000540561.1
TAOK3
TAO kinase 3
chr11_-_62521614 0.26 ENST00000527994.1
ENST00000394807.3
ZBTB3
zinc finger and BTB domain containing 3
chr13_-_46716969 0.26 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr3_-_183145873 0.26 ENST00000447025.2
ENST00000414362.2
ENST00000328913.3
MCF2L2
MCF.2 cell line derived transforming sequence-like 2
chr2_-_158295915 0.26 ENST00000418920.1
CYTIP
cytohesin 1 interacting protein
chr5_+_40841276 0.25 ENST00000254691.5
CARD6
caspase recruitment domain family, member 6
chr1_-_178840157 0.25 ENST00000367629.1
ENST00000234816.2
ANGPTL1
angiopoietin-like 1
chr6_+_42989344 0.25 ENST00000244496.5
RRP36
ribosomal RNA processing 36 homolog (S. cerevisiae)
chr18_-_64271316 0.24 ENST00000540086.1
ENST00000580157.1
CDH19
cadherin 19, type 2
chr10_-_95242044 0.24 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
MYOF
myoferlin
chr19_+_14693888 0.24 ENST00000547437.1
ENST00000397439.2
ENST00000417570.1
CLEC17A
C-type lectin domain family 17, member A
chr2_-_217559517 0.23 ENST00000449583.1
IGFBP5
insulin-like growth factor binding protein 5
chr20_-_33735070 0.23 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr19_+_3185910 0.23 ENST00000588428.1
NCLN
nicalin
chr4_+_26344754 0.23 ENST00000515573.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr11_-_107729504 0.22 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr6_+_31105426 0.22 ENST00000547221.1
PSORS1C1
psoriasis susceptibility 1 candidate 1
chrX_-_100872911 0.21 ENST00000361910.4
ENST00000539247.1
ENST00000538627.1
ARMCX6
armadillo repeat containing, X-linked 6
chr11_-_62609281 0.21 ENST00000525239.1
ENST00000538098.2
WDR74
WD repeat domain 74
chr17_-_47786375 0.20 ENST00000511657.1
SLC35B1
solute carrier family 35, member B1
chr11_-_107729887 0.20 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr13_+_49551020 0.20 ENST00000541916.1
FNDC3A
fibronectin type III domain containing 3A
chr12_-_10282836 0.19 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A
C-type lectin domain family 7, member A
chrX_-_84634708 0.19 ENST00000373145.3
POF1B
premature ovarian failure, 1B
chr19_-_46234119 0.19 ENST00000317683.3
FBXO46
F-box protein 46
chrX_-_77225135 0.18 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr13_+_24144796 0.18 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr14_-_23058063 0.18 ENST00000538631.1
ENST00000543337.1
ENST00000250498.4
DAD1
defender against cell death 1
chr14_+_92789498 0.18 ENST00000531433.1
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr12_+_122356488 0.17 ENST00000397454.2
WDR66
WD repeat domain 66
chr1_-_168464875 0.17 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr5_+_102200948 0.17 ENST00000511477.1
ENST00000506006.1
ENST00000509832.1
PAM
peptidylglycine alpha-amidating monooxygenase
chr15_+_64680003 0.17 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr2_+_105050794 0.17 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chr4_-_69111401 0.17 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr2_-_217560248 0.16 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr2_+_234668894 0.16 ENST00000305208.5
ENST00000608383.1
ENST00000360418.3
UGT1A8
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr20_+_30102231 0.15 ENST00000335574.5
ENST00000340852.5
ENST00000398174.3
ENST00000376127.3
ENST00000344042.5
HM13
histocompatibility (minor) 13
chr1_-_21377383 0.15 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr17_-_48785216 0.15 ENST00000285243.6
ANKRD40
ankyrin repeat domain 40
chr7_-_45151272 0.15 ENST00000461363.1
ENST00000495078.1
ENST00000494076.1
ENST00000478532.1
ENST00000258770.3
ENST00000361278.3
TBRG4
transforming growth factor beta regulator 4
chr14_+_61449197 0.15 ENST00000533744.2
SLC38A6
solute carrier family 38, member 6
chr2_-_145277569 0.15 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chr4_+_25162253 0.15 ENST00000512921.1
PI4K2B
phosphatidylinositol 4-kinase type 2 beta
chr12_-_46121554 0.15 ENST00000609803.1
LINC00938
long intergenic non-protein coding RNA 938
chr15_+_48483736 0.13 ENST00000417307.2
ENST00000559641.1
CTXN2
SLC12A1
cortexin 2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr1_-_13390765 0.13 ENST00000357367.2
PRAMEF8
PRAME family member 8
chr14_-_90798273 0.13 ENST00000357904.3
NRDE2
NRDE-2, necessary for RNA interference, domain containing
chr2_+_88047606 0.12 ENST00000359481.4
PLGLB2
plasminogen-like B2
chr11_+_101983176 0.12 ENST00000524575.1
YAP1
Yes-associated protein 1
chr14_-_60043524 0.12 ENST00000537690.2
ENST00000281581.4
CCDC175
coiled-coil domain containing 175
chr15_+_79166065 0.12 ENST00000559690.1
ENST00000559158.1
MORF4L1
mortality factor 4 like 1
chrX_-_48931648 0.12 ENST00000376386.3
ENST00000376390.4
PRAF2
PRA1 domain family, member 2
chr6_-_47445214 0.11 ENST00000604014.1
RP11-385F7.1
RP11-385F7.1
chr1_-_232651312 0.11 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr18_-_3845293 0.11 ENST00000400145.2
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chrX_-_15332665 0.11 ENST00000537676.1
ENST00000344384.4
ASB11
ankyrin repeat and SOCS box containing 11
chr3_-_157221380 0.11 ENST00000468233.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr5_-_130500922 0.11 ENST00000513012.1
ENST00000508488.1
ENST00000506908.1
ENST00000304043.5
HINT1
histidine triad nucleotide binding protein 1
chr2_-_169887827 0.11 ENST00000263817.6
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr9_-_99540328 0.11 ENST00000223428.4
ENST00000375231.1
ENST00000374641.3
ZNF510
zinc finger protein 510
chr11_-_63376013 0.10 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chrX_-_32173579 0.09 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
DMD
dystrophin
chr7_-_107883678 0.09 ENST00000417701.1
NRCAM
neuronal cell adhesion molecule
chr3_+_169629354 0.09 ENST00000428432.2
ENST00000335556.3
SAMD7
sterile alpha motif domain containing 7
chr17_+_7155819 0.09 ENST00000570322.1
ENST00000576496.1
ENST00000574841.2
ELP5
elongator acetyltransferase complex subunit 5
chr18_-_64271363 0.09 ENST00000262150.2
CDH19
cadherin 19, type 2
chr1_-_95391315 0.09 ENST00000545882.1
ENST00000415017.1
CNN3
calponin 3, acidic
chr1_+_15668240 0.09 ENST00000444385.1
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr5_-_54988559 0.09 ENST00000502247.1
SLC38A9
solute carrier family 38, member 9
chr12_-_118628350 0.08 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr1_+_160370344 0.08 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr7_-_55930443 0.08 ENST00000388975.3
SEPT14
septin 14
chr4_+_26324474 0.08 ENST00000514675.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr2_-_166060382 0.08 ENST00000409101.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr10_-_74283694 0.08 ENST00000398763.4
ENST00000418483.2
ENST00000489666.2
MICU1
mitochondrial calcium uptake 1
chr1_-_223853348 0.08 ENST00000366872.5
CAPN8
calpain 8
chr9_-_28670283 0.08 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr5_+_40909354 0.07 ENST00000313164.9
C7
complement component 7
chr1_+_149871135 0.07 ENST00000369152.5
BOLA1
bolA family member 1
chr1_+_63063152 0.07 ENST00000371129.3
ANGPTL3
angiopoietin-like 3
chrX_+_102840408 0.07 ENST00000468024.1
ENST00000472484.1
ENST00000415568.2
ENST00000490644.1
ENST00000459722.1
ENST00000472745.1
ENST00000494801.1
ENST00000434216.2
ENST00000425011.1
TCEAL4
transcription elongation factor A (SII)-like 4
chr14_+_38677123 0.07 ENST00000267377.2
SSTR1
somatostatin receptor 1
chr3_+_159943362 0.07 ENST00000326474.3
C3orf80
chromosome 3 open reading frame 80
chr6_-_152639479 0.07 ENST00000356820.4
SYNE1
spectrin repeat containing, nuclear envelope 1
chr5_-_41794313 0.06 ENST00000512084.1
OXCT1
3-oxoacid CoA transferase 1
chr14_-_90798418 0.06 ENST00000354366.3
NRDE2
NRDE-2, necessary for RNA interference, domain containing
chr18_-_53303123 0.06 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chr15_-_42500351 0.06 ENST00000348544.4
ENST00000318006.5
VPS39
vacuolar protein sorting 39 homolog (S. cerevisiae)
chr8_+_92261516 0.06 ENST00000276609.3
ENST00000309536.2
SLC26A7
solute carrier family 26 (anion exchanger), member 7
chr3_+_134514093 0.06 ENST00000398015.3
EPHB1
EPH receptor B1
chr8_+_38662960 0.06 ENST00000524193.1
TACC1
transforming, acidic coiled-coil containing protein 1
chr21_+_39644305 0.06 ENST00000398930.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr2_-_85108363 0.06 ENST00000335459.5
TRABD2A
TraB domain containing 2A
chr11_+_12132117 0.06 ENST00000256194.4
MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
chrX_+_65384182 0.06 ENST00000441993.2
ENST00000419594.1
HEPH
hephaestin
chr20_-_50722183 0.05 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr19_-_36001113 0.05 ENST00000434389.1
DMKN
dermokine
chr10_-_29923893 0.05 ENST00000355867.4
SVIL
supervillin
chr10_-_5046042 0.05 ENST00000421196.3
ENST00000455190.1
AKR1C2
aldo-keto reductase family 1, member C2
chr8_-_116504448 0.05 ENST00000518018.1
TRPS1
trichorhinophalangeal syndrome I
chr12_-_10282742 0.05 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A
C-type lectin domain family 7, member A
chr11_+_73498898 0.05 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
MRPL48
mitochondrial ribosomal protein L48
chr12_-_54689532 0.05 ENST00000540264.2
ENST00000312156.4
NFE2
nuclear factor, erythroid 2
chr7_-_151330218 0.05 ENST00000476632.1
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chrX_+_65382433 0.04 ENST00000374727.3
HEPH
hephaestin
chr4_-_48116540 0.04 ENST00000506073.1
TXK
TXK tyrosine kinase
chr18_-_3845321 0.04 ENST00000539435.1
ENST00000400147.2
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr17_-_7307358 0.04 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
TMEM256
TMEM256-PLSCR3
transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr4_+_169418255 0.04 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr7_-_115670804 0.04 ENST00000320239.7
TFEC
transcription factor EC
chr2_+_74685413 0.04 ENST00000233615.2
WBP1
WW domain binding protein 1
chr2_+_32502952 0.03 ENST00000238831.4
YIPF4
Yip1 domain family, member 4
chr9_-_95166841 0.03 ENST00000262551.4
OGN
osteoglycin
chr21_+_39644395 0.02 ENST00000398934.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr13_+_24144509 0.02 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr8_-_30706608 0.02 ENST00000256246.2
TEX15
testis expressed 15
chrX_+_65382381 0.02 ENST00000519389.1
HEPH
hephaestin
chr7_-_115670792 0.02 ENST00000265440.7
ENST00000393485.1
TFEC
transcription factor EC
chr11_+_86085778 0.02 ENST00000354755.1
ENST00000278487.3
ENST00000531271.1
ENST00000445632.2
CCDC81
coiled-coil domain containing 81
chr9_-_21482312 0.01 ENST00000448696.3
IFNE
interferon, epsilon
chr1_+_149871171 0.01 ENST00000369150.1
BOLA1
bolA family member 1
chr2_-_190446738 0.01 ENST00000427419.1
ENST00000455320.1
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr7_+_13141097 0.01 ENST00000411542.1
AC011288.2
AC011288.2
chr12_-_95945246 0.01 ENST00000258499.3
USP44
ubiquitin specific peptidase 44
chrM_+_9207 0.00 ENST00000362079.2
MT-CO3
mitochondrially encoded cytochrome c oxidase III
chr17_+_4710391 0.00 ENST00000263088.6
ENST00000572940.1
PLD2
phospholipase D2
chr2_-_197675000 0.00 ENST00000342506.2
C2orf66
chromosome 2 open reading frame 66
chr1_-_238108575 0.00 ENST00000604646.1
MTRNR2L11
MT-RNR2-like 11 (pseudogene)
chr12_+_26164645 0.00 ENST00000542004.1
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8

Network of associatons between targets according to the STRING database.

First level regulatory network of ISL2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.4 GO:1904204 skeletal muscle hypertrophy(GO:0014734) regulation of skeletal muscle hypertrophy(GO:1904204)
0.1 0.3 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.3 GO:0015692 lead ion transport(GO:0015692)
0.1 0.2 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 0.2 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.2 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 1.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.5 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.3 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.4 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.2 GO:0018032 protein amidation(GO:0018032)
0.0 0.1 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0051389 inactivation of MAPKK activity(GO:0051389) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.5 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.1 GO:1904806 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.0 0.1 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.3 GO:0030155 regulation of cell adhesion(GO:0030155)
0.0 0.3 GO:0051290 protein heterotetramerization(GO:0051290)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.2 GO:0001534 radial spoke(GO:0001534)
0.1 0.3 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.4 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.3 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.2 GO:0042806 fucose binding(GO:0042806)
0.0 0.2 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.1 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.0 0.2 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.6 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle