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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for KLF15

Z-value: 0.58

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Transcription factors associated with KLF15

Gene Symbol Gene ID Gene Info
KLF15
ENSG00000163884.3 Kruppel like factor 15

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF15hg19_v2_chr3_-_126076264_1260763050.475.3e-01Click!

Activity profile of KLF15 motif

Sorted Z-values of KLF15 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_5832799 0.35 ENST00000322002.3
SOX11
SRY (sex determining region Y)-box 11
chr5_+_17217669 0.34 ENST00000322611.3
BASP1
brain abundant, membrane attached signal protein 1
chr19_-_10047219 0.33 ENST00000264833.4
OLFM2
olfactomedin 2
chr2_+_155554797 0.32 ENST00000295101.2
KCNJ3
potassium inwardly-rectifying channel, subfamily J, member 3
chr17_+_45771420 0.29 ENST00000578982.1
TBKBP1
TBK1 binding protein 1
chr16_+_81478775 0.27 ENST00000537098.3
CMIP
c-Maf inducing protein
chr14_+_93673574 0.26 ENST00000554232.1
ENST00000556871.1
ENST00000555113.1
UBR7
ubiquitin protein ligase E3 component n-recognin 7 (putative)
chr19_-_49362621 0.23 ENST00000594195.1
ENST00000595867.1
PLEKHA4
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr10_+_8096769 0.23 ENST00000346208.3
GATA3
GATA binding protein 3
chrX_+_53078465 0.22 ENST00000375466.2
GPR173
G protein-coupled receptor 173
chr22_-_50970506 0.21 ENST00000428989.2
ENST00000403326.1
ODF3B
outer dense fiber of sperm tails 3B
chr16_+_2802623 0.20 ENST00000576924.1
ENST00000575009.1
ENST00000576415.1
ENST00000571378.1
SRRM2
serine/arginine repetitive matrix 2
chr5_+_61602236 0.20 ENST00000514082.1
ENST00000407818.3
KIF2A
kinesin heavy chain member 2A
chr14_-_55738788 0.20 ENST00000556183.1
RP11-665C16.6
RP11-665C16.6
chr22_-_20792089 0.19 ENST00000405555.3
ENST00000266214.5
SCARF2
scavenger receptor class F, member 2
chr11_-_64410787 0.19 ENST00000301894.2
NRXN2
neurexin 2
chr17_-_36760865 0.19 ENST00000584266.1
SRCIN1
SRC kinase signaling inhibitor 1
chr18_-_51750948 0.19 ENST00000583046.1
ENST00000398398.2
MBD2
methyl-CpG binding domain protein 2
chr10_-_79397547 0.19 ENST00000481070.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr12_-_30907862 0.18 ENST00000541765.1
ENST00000537108.1
CAPRIN2
caprin family member 2
chr1_+_198126209 0.17 ENST00000367383.1
NEK7
NIMA-related kinase 7
chr19_-_47975143 0.17 ENST00000597014.1
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr9_-_117267717 0.17 ENST00000374057.3
DFNB31
deafness, autosomal recessive 31
chr11_+_74951948 0.16 ENST00000562197.2
TPBGL
trophoblast glycoprotein-like
chr17_-_78450398 0.16 ENST00000306773.4
NPTX1
neuronal pentraxin I
chr10_-_22292675 0.16 ENST00000376946.1
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr12_+_57854274 0.16 ENST00000528432.1
GLI1
GLI family zinc finger 1
chr2_-_230786679 0.16 ENST00000543084.1
ENST00000343290.5
ENST00000389044.4
ENST00000283943.5
TRIP12
thyroid hormone receptor interactor 12
chr2_-_200322723 0.15 ENST00000417098.1
SATB2
SATB homeobox 2
chr11_-_31839488 0.15 ENST00000419022.1
ENST00000379132.3
ENST00000379129.2
PAX6
paired box 6
chrX_-_48693955 0.15 ENST00000218230.5
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr22_+_19118321 0.15 ENST00000399635.2
TSSK2
testis-specific serine kinase 2
chr6_+_32811885 0.14 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAPSAR1
PSMB9
TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chr14_-_69445793 0.14 ENST00000538545.2
ENST00000394419.4
ACTN1
actinin, alpha 1
chr10_+_28822236 0.14 ENST00000347934.4
ENST00000354911.4
WAC
WW domain containing adaptor with coiled-coil
chr10_-_101380121 0.14 ENST00000370495.4
SLC25A28
solute carrier family 25 (mitochondrial iron transporter), member 28
chr5_+_131593364 0.14 ENST00000253754.3
ENST00000379018.3
PDLIM4
PDZ and LIM domain 4
chr11_-_65325664 0.14 ENST00000301873.5
LTBP3
latent transforming growth factor beta binding protein 3
chr4_+_39640787 0.14 ENST00000532680.1
RP11-539G18.2
RP11-539G18.2
chr19_-_46272106 0.13 ENST00000560168.1
SIX5
SIX homeobox 5
chr19_-_45661995 0.13 ENST00000438936.2
NKPD1
NTPase, KAP family P-loop domain containing 1
chr17_-_4545170 0.13 ENST00000576394.1
ENST00000574640.1
ALOX15
arachidonate 15-lipoxygenase
chr1_+_206680879 0.13 ENST00000355294.4
ENST00000367117.3
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr22_+_42470289 0.13 ENST00000419475.1
FAM109B
family with sequence similarity 109, member B
chr11_-_134095335 0.13 ENST00000534227.1
ENST00000532445.1
NCAPD3
non-SMC condensin II complex, subunit D3
chr2_+_45878790 0.13 ENST00000306156.3
PRKCE
protein kinase C, epsilon
chr8_+_81397876 0.12 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr10_+_28822417 0.12 ENST00000428935.1
ENST00000420266.1
WAC
WW domain containing adaptor with coiled-coil
chrX_-_19905703 0.12 ENST00000397821.3
SH3KBP1
SH3-domain kinase binding protein 1
chr3_-_88108212 0.12 ENST00000482016.1
CGGBP1
CGG triplet repeat binding protein 1
chr7_-_151107106 0.12 ENST00000334493.6
WDR86
WD repeat domain 86
chr22_-_50699972 0.12 ENST00000395778.3
MAPK12
mitogen-activated protein kinase 12
chr15_+_90728145 0.12 ENST00000561085.1
ENST00000379122.3
ENST00000332496.6
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr12_+_52404270 0.12 ENST00000552049.1
ENST00000546756.1
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr21_-_27107344 0.11 ENST00000457143.2
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr2_-_230786378 0.11 ENST00000430954.1
TRIP12
thyroid hormone receptor interactor 12
chr4_+_74702214 0.11 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chrX_+_154114635 0.11 ENST00000369446.2
F8A1
coagulation factor VIII-associated 1
chr2_-_198175495 0.11 ENST00000409153.1
ENST00000409919.1
ENST00000539527.1
ANKRD44
ankyrin repeat domain 44
chr8_+_21777243 0.11 ENST00000521303.1
XPO7
exportin 7
chr12_+_109592477 0.11 ENST00000544726.1
ACACB
acetyl-CoA carboxylase beta
chr19_-_46272462 0.11 ENST00000317578.6
SIX5
SIX homeobox 5
chr2_+_232573208 0.11 ENST00000409115.3
PTMA
prothymosin, alpha
chr19_-_47975417 0.11 ENST00000236877.6
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr19_-_14201507 0.11 ENST00000533683.2
SAMD1
sterile alpha motif domain containing 1
chr19_-_38806540 0.11 ENST00000592694.1
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr18_-_21977748 0.10 ENST00000399441.4
ENST00000319481.3
OSBPL1A
oxysterol binding protein-like 1A
chr17_-_4463856 0.10 ENST00000574584.1
ENST00000381550.3
ENST00000301395.3
GGT6
gamma-glutamyltransferase 6
chr1_-_179198702 0.10 ENST00000502732.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr16_+_30709530 0.10 ENST00000411466.2
SRCAP
Snf2-related CREBBP activator protein
chr1_-_244013384 0.10 ENST00000366539.1
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr22_+_39745930 0.10 ENST00000318801.4
ENST00000216155.7
ENST00000406293.3
ENST00000328933.5
SYNGR1
synaptogyrin 1
chr7_+_128312346 0.10 ENST00000480462.1
ENST00000378704.3
ENST00000477515.1
FAM71F2
family with sequence similarity 71, member F2
chr21_-_27107198 0.10 ENST00000400094.1
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr1_-_243418650 0.10 ENST00000522995.1
CEP170
centrosomal protein 170kDa
chr19_+_852291 0.10 ENST00000263621.1
ELANE
elastase, neutrophil expressed
chr17_+_42634844 0.10 ENST00000315323.3
FZD2
frizzled family receptor 2
chr7_-_100493482 0.10 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
ACHE
acetylcholinesterase (Yt blood group)
chr7_-_154863264 0.10 ENST00000395731.2
ENST00000543018.1
HTR5A-AS1
HTR5A antisense RNA 1
chr17_-_17399701 0.10 ENST00000225688.3
ENST00000579152.1
RASD1
RAS, dexamethasone-induced 1
chr3_-_49726104 0.10 ENST00000383728.3
ENST00000545762.1
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr13_-_52027134 0.09 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr19_-_38806560 0.09 ENST00000591755.1
ENST00000337679.8
ENST00000339413.6
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr7_+_92158083 0.09 ENST00000265732.5
ENST00000481551.1
ENST00000496410.1
RBM48
RNA binding motif protein 48
chr20_+_44650348 0.09 ENST00000454036.2
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr11_-_46142505 0.09 ENST00000524497.1
ENST00000418153.2
PHF21A
PHD finger protein 21A
chr1_-_110933663 0.09 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4
solute carrier family 16, member 4
chr11_-_46142615 0.09 ENST00000529734.1
ENST00000323180.6
PHF21A
PHD finger protein 21A
chr15_-_65067773 0.09 ENST00000300069.4
RBPMS2
RNA binding protein with multiple splicing 2
chr17_+_78234625 0.09 ENST00000508628.2
ENST00000582970.1
ENST00000456466.1
ENST00000319921.4
RNF213
ring finger protein 213
chr7_-_92157760 0.09 ENST00000248633.4
PEX1
peroxisomal biogenesis factor 1
chr2_+_74212073 0.09 ENST00000441217.1
AC073046.25
AC073046.25
chr1_+_37940153 0.09 ENST00000373087.6
ZC3H12A
zinc finger CCCH-type containing 12A
chr21_+_30671189 0.09 ENST00000286800.3
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr2_-_230786619 0.09 ENST00000389045.3
ENST00000409677.1
TRIP12
thyroid hormone receptor interactor 12
chr19_-_40790993 0.09 ENST00000596634.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr2_+_46926326 0.09 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr2_-_233792837 0.09 ENST00000373552.4
ENST00000409079.1
NGEF
neuronal guanine nucleotide exchange factor
chr19_+_8117636 0.09 ENST00000253451.4
ENST00000315626.4
CCL25
chemokine (C-C motif) ligand 25
chr19_-_4124079 0.09 ENST00000394867.4
ENST00000262948.5
MAP2K2
mitogen-activated protein kinase kinase 2
chr9_+_88556444 0.09 ENST00000376040.1
NAA35
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr2_+_39893043 0.08 ENST00000281961.2
TMEM178A
transmembrane protein 178A
chr10_+_8096631 0.08 ENST00000379328.3
GATA3
GATA binding protein 3
chr16_-_755726 0.08 ENST00000324361.5
FBXL16
F-box and leucine-rich repeat protein 16
chr1_+_150898733 0.08 ENST00000525956.1
SETDB1
SET domain, bifurcated 1
chr4_+_56719782 0.08 ENST00000381295.2
ENST00000346134.7
ENST00000349598.6
EXOC1
exocyst complex component 1
chr4_-_1657135 0.08 ENST00000489029.1
FAM53A
family with sequence similarity 53, member A
chr2_+_198669365 0.08 ENST00000428675.1
PLCL1
phospholipase C-like 1
chr20_-_62680984 0.08 ENST00000340356.7
SOX18
SRY (sex determining region Y)-box 18
chr11_-_62457371 0.08 ENST00000317449.4
LRRN4CL
LRRN4 C-terminal like
chr1_+_33283043 0.08 ENST00000373476.1
ENST00000373475.5
ENST00000529027.1
ENST00000398243.3
S100PBP
S100P binding protein
chr9_-_139891165 0.08 ENST00000494426.1
CLIC3
chloride intracellular channel 3
chr7_+_89841024 0.08 ENST00000394626.1
STEAP2
STEAP family member 2, metalloreductase
chr1_-_110933611 0.08 ENST00000472422.2
ENST00000437429.2
SLC16A4
solute carrier family 16, member 4
chr10_+_76871454 0.08 ENST00000372687.4
SAMD8
sterile alpha motif domain containing 8
chr19_-_6424783 0.08 ENST00000398148.3
KHSRP
KH-type splicing regulatory protein
chr12_+_120933859 0.08 ENST00000242577.6
ENST00000548214.1
ENST00000392508.2
DYNLL1
dynein, light chain, LC8-type 1
chr7_+_144052381 0.08 ENST00000498580.1
ENST00000056217.5
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr10_+_76871353 0.08 ENST00000542569.1
SAMD8
sterile alpha motif domain containing 8
chr7_-_92157747 0.08 ENST00000428214.1
ENST00000438045.1
PEX1
peroxisomal biogenesis factor 1
chr2_+_201171268 0.08 ENST00000423749.1
ENST00000428692.1
ENST00000457757.1
ENST00000453663.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr18_+_3449695 0.08 ENST00000343820.5
TGIF1
TGFB-induced factor homeobox 1
chr15_+_40544749 0.08 ENST00000559617.1
ENST00000560684.1
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr7_+_116139744 0.08 ENST00000343213.2
CAV2
caveolin 2
chr10_-_121356518 0.08 ENST00000369092.4
TIAL1
TIA1 cytotoxic granule-associated RNA binding protein-like 1
chr13_-_52026730 0.08 ENST00000420668.2
INTS6
integrator complex subunit 6
chr8_-_105601134 0.07 ENST00000276654.5
ENST00000424843.2
LRP12
low density lipoprotein receptor-related protein 12
chr14_+_92980111 0.07 ENST00000216487.7
ENST00000557762.1
RIN3
Ras and Rab interactor 3
chr2_-_45166338 0.07 ENST00000437916.2
RP11-89K21.1
RP11-89K21.1
chr19_-_11689752 0.07 ENST00000592659.1
ENST00000592828.1
ENST00000218758.5
ENST00000412435.2
ACP5
acid phosphatase 5, tartrate resistant
chr3_+_140770183 0.07 ENST00000310546.2
SPSB4
splA/ryanodine receptor domain and SOCS box containing 4
chr7_+_29519662 0.07 ENST00000424025.2
ENST00000439711.2
ENST00000421775.2
CHN2
chimerin 2
chr21_-_27107283 0.07 ENST00000284971.3
ENST00000400099.1
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr13_-_108867846 0.07 ENST00000442234.1
LIG4
ligase IV, DNA, ATP-dependent
chr6_-_29595779 0.07 ENST00000355973.3
ENST00000377012.4
GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr7_-_143059780 0.07 ENST00000409578.1
ENST00000409346.1
FAM131B
family with sequence similarity 131, member B
chr21_-_27107881 0.07 ENST00000400090.3
ENST00000400087.3
ENST00000400093.3
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr13_-_45151259 0.07 ENST00000493016.1
TSC22D1
TSC22 domain family, member 1
chr19_-_3062465 0.07 ENST00000327141.4
AES
amino-terminal enhancer of split
chr2_-_39347524 0.07 ENST00000395038.2
ENST00000402219.2
SOS1
son of sevenless homolog 1 (Drosophila)
chr2_-_9143786 0.07 ENST00000462696.1
ENST00000305997.3
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr12_+_120933904 0.07 ENST00000550178.1
ENST00000550845.1
ENST00000549989.1
ENST00000552870.1
DYNLL1
dynein, light chain, LC8-type 1
chr11_-_65641044 0.07 ENST00000527378.1
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr16_+_3162557 0.07 ENST00000382192.3
ENST00000219091.4
ENST00000444510.2
ENST00000414351.1
ZNF205
zinc finger protein 205
chr12_+_53774423 0.07 ENST00000426431.2
SP1
Sp1 transcription factor
chr3_-_185826286 0.07 ENST00000537818.1
ENST00000422039.1
ENST00000434744.1
ETV5
ets variant 5
chr19_-_47249679 0.07 ENST00000263280.6
STRN4
striatin, calmodulin binding protein 4
chr11_+_50257784 0.07 ENST00000529219.1
RP11-347H15.4
RP11-347H15.4
chr6_-_94129244 0.07 ENST00000369303.4
ENST00000369297.1
EPHA7
EPH receptor A7
chrX_+_119495934 0.07 ENST00000218008.3
ENST00000361319.3
ENST00000539306.1
ATP1B4
ATPase, Na+/K+ transporting, beta 4 polypeptide
chr5_-_131132658 0.07 ENST00000514667.1
ENST00000511848.1
ENST00000510461.1
CTC-432M15.3
FNIP1
Folliculin-interacting protein 1
folliculin interacting protein 1
chr2_+_232573222 0.06 ENST00000341369.7
ENST00000409683.1
PTMA
prothymosin, alpha
chr7_-_151217001 0.06 ENST00000262187.5
RHEB
Ras homolog enriched in brain
chr2_-_208030647 0.06 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr14_+_24837226 0.06 ENST00000554050.1
ENST00000554903.1
ENST00000554779.1
ENST00000250373.4
ENST00000553708.1
NFATC4
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
chr14_-_51562037 0.06 ENST00000338969.5
TRIM9
tripartite motif containing 9
chr9_+_137533615 0.06 ENST00000371817.3
COL5A1
collagen, type V, alpha 1
chr19_-_55866061 0.06 ENST00000588572.2
ENST00000593184.1
ENST00000589467.1
COX6B2
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr16_-_30107491 0.06 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
YPEL3
yippee-like 3 (Drosophila)
chr17_-_27332931 0.06 ENST00000442608.3
ENST00000335960.6
SEZ6
seizure related 6 homolog (mouse)
chr12_-_50101003 0.06 ENST00000550488.1
FMNL3
formin-like 3
chr1_-_21503337 0.06 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr16_+_30969055 0.06 ENST00000452917.1
SETD1A
SET domain containing 1A
chr21_-_40685504 0.06 ENST00000380800.3
BRWD1
bromodomain and WD repeat domain containing 1
chr13_+_98795434 0.06 ENST00000376586.2
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr11_+_119076745 0.06 ENST00000264033.4
CBL
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr3_-_27763803 0.06 ENST00000449599.1
EOMES
eomesodermin
chr16_+_50300427 0.06 ENST00000394697.2
ENST00000566433.2
ENST00000538642.1
ADCY7
adenylate cyclase 7
chr17_-_76921459 0.06 ENST00000262768.7
TIMP2
TIMP metallopeptidase inhibitor 2
chr7_+_89841000 0.06 ENST00000287908.3
STEAP2
STEAP family member 2, metalloreductase
chr2_-_153573965 0.06 ENST00000448428.1
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr14_-_73493784 0.06 ENST00000553891.1
ZFYVE1
zinc finger, FYVE domain containing 1
chr19_+_41082755 0.06 ENST00000291842.5
ENST00000600733.1
SHKBP1
SH3KBP1 binding protein 1
chr2_-_73511559 0.06 ENST00000521871.1
FBXO41
F-box protein 41
chr19_-_47975106 0.06 ENST00000539381.1
ENST00000594353.1
ENST00000542837.1
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr8_+_9413410 0.06 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr17_-_58469687 0.06 ENST00000590133.1
USP32
ubiquitin specific peptidase 32
chr10_+_114709999 0.05 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr2_-_70780770 0.05 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
TGFA
transforming growth factor, alpha
chr19_+_589893 0.05 ENST00000251287.2
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr11_-_117667806 0.05 ENST00000527706.1
ENST00000321322.6
DSCAML1
Down syndrome cell adhesion molecule like 1
chr17_-_4852332 0.05 ENST00000572383.1
PFN1
profilin 1
chr12_-_131323719 0.05 ENST00000392373.2
STX2
syntaxin 2
chr19_-_50400212 0.05 ENST00000391826.2
IL4I1
interleukin 4 induced 1
chr1_+_180199393 0.05 ENST00000263726.2
LHX4
LIM homeobox 4
chr15_+_72766651 0.05 ENST00000379887.4
ARIH1
ariadne RBR E3 ubiquitin protein ligase 1
chr1_+_203765437 0.05 ENST00000550078.1
ZBED6
zinc finger, BED-type containing 6
chr17_-_42277203 0.05 ENST00000587097.1
ATXN7L3
ataxin 7-like 3
chr2_-_198650037 0.05 ENST00000392296.4
BOLL
boule-like RNA-binding protein
chr11_-_72353451 0.05 ENST00000376450.3
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr3_+_101546827 0.05 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr19_-_42636617 0.05 ENST00000529067.1
ENST00000529952.1
ENST00000533720.1
ENST00000389341.5
ENST00000342301.4
POU2F2
POU class 2 homeobox 2
chr18_-_57364588 0.05 ENST00000439986.4
CCBE1
collagen and calcium binding EGF domains 1
chr17_-_27278445 0.05 ENST00000268756.3
ENST00000584685.1
PHF12
PHD finger protein 12
chr1_-_27930102 0.05 ENST00000247087.5
ENST00000374011.2
AHDC1
AT hook, DNA binding motif, containing 1
chr2_-_37193606 0.05 ENST00000379213.2
ENST00000263918.4
STRN
striatin, calmodulin binding protein
chr1_-_151689259 0.05 ENST00000420342.1
ENST00000290583.4
CELF3
CUGBP, Elav-like family member 3
chr18_+_48405419 0.05 ENST00000321341.5
ME2
malic enzyme 2, NAD(+)-dependent, mitochondrial
chr3_-_149688502 0.05 ENST00000481767.1
ENST00000475518.1
PFN2
profilin 2
chr19_+_45754505 0.05 ENST00000262891.4
ENST00000300843.4
MARK4
MAP/microtubule affinity-regulating kinase 4

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF15

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0061386 closure of optic fissure(GO:0061386)
0.1 0.3 GO:0061290 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) negative regulation of DNA demethylation(GO:1901536)
0.1 0.3 GO:0007356 thorax and anterior abdomen determination(GO:0007356) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.1 0.3 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 0.2 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.1 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.0 0.2 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.2 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.4 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.3 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.1 GO:0035668 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 0.1 GO:2000625 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.0 0.2 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.1 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.0 0.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.1 GO:1902462 mesenchymal stem cell proliferation(GO:0097168) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0060214 endocardium formation(GO:0060214)
0.0 0.1 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.1 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.3 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0070945 antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778) neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.0 GO:0015728 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.1 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.0 GO:0044727 chromatin reprogramming in the zygote(GO:0044725) DNA demethylation of male pronucleus(GO:0044727)
0.0 0.0 GO:0035981 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.0 0.3 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.2 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.0 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.0 GO:0019085 early viral transcription(GO:0019085)
0.0 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.1 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) positive regulation of dopamine receptor signaling pathway(GO:0060161) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.0 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.1 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726) regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.0 GO:0097106 postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107)
0.0 0.0 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.0 0.1 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.0 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.0 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.1 0.3 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0050473 hepoxilin-epoxide hydrolase activity(GO:0047977) arachidonate 15-lipoxygenase activity(GO:0050473)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.1 GO:0035276 ethanol binding(GO:0035276)
0.0 0.2 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.0 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.0 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network