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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for LHX2

Z-value: 0.32

Motif logo

Transcription factors associated with LHX2

Gene Symbol Gene ID Gene Info
ENSG00000106689.6 LIM homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX2hg19_v2_chr9_+_126777676_126777700-0.435.7e-01Click!

Activity profile of LHX2 motif

Sorted Z-values of LHX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_11129229 0.16 ENST00000608176.1
ENST00000433747.2
ENST00000608576.1
ENST00000608916.1
RP11-120D5.1
chr15_-_42565023 0.16 ENST00000566474.1
transmembrane protein 87A
chr2_-_55237484 0.14 ENST00000394609.2
reticulon 4
chr14_+_56078695 0.14 ENST00000416613.1
kinectin 1 (kinesin receptor)
chr12_-_25348007 0.13 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
cancer susceptibility candidate 1
chr9_-_77643307 0.13 ENST00000376834.3
ENST00000376830.3
chromosome 9 open reading frame 41
chrX_+_18725758 0.12 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
protein phosphatase, EF-hand calcium binding domain 1
chr2_+_200472779 0.11 ENST00000427045.1
ENST00000419243.1
AC093590.1
chr8_-_109260897 0.11 ENST00000521297.1
ENST00000519030.1
ENST00000521440.1
ENST00000518345.1
ENST00000519627.1
ENST00000220849.5
eukaryotic translation initiation factor 3, subunit E
chr4_-_105416039 0.11 ENST00000394767.2
CXXC finger protein 4
chrY_+_15418467 0.10 ENST00000595988.1
Uncharacterized protein
chr10_+_95326416 0.10 ENST00000371481.4
ENST00000371483.4
ENST00000604414.1
free fatty acid receptor 4
chr12_+_94071129 0.10 ENST00000552983.1
ENST00000332896.3
ENST00000552033.1
ENST00000548483.1
CASP2 and RIPK1 domain containing adaptor with death domain
chr12_-_10978957 0.10 ENST00000240619.2
taste receptor, type 2, member 10
chr12_+_41136144 0.09 ENST00000548005.1
ENST00000552248.1
contactin 1
chr2_-_55276320 0.09 ENST00000357376.3
reticulon 4
chr3_+_38017264 0.09 ENST00000436654.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr6_-_26043885 0.08 ENST00000357905.2
histone cluster 1, H2bb
chr6_+_26199737 0.08 ENST00000359985.1
histone cluster 1, H2bf
chr21_-_27423339 0.08 ENST00000415997.1
amyloid beta (A4) precursor protein
chr20_+_31870927 0.08 ENST00000253354.1
BPI fold containing family B, member 1
chr5_-_133702761 0.08 ENST00000521118.1
ENST00000265334.4
ENST00000435211.1
cyclin-dependent kinase-like 3
chr7_+_37960163 0.08 ENST00000199448.4
ENST00000559325.1
ENST00000423717.1
ependymin related 1
chr4_-_57253587 0.08 ENST00000513376.1
ENST00000602986.1
ENST00000434343.2
ENST00000451613.1
ENST00000205214.6
ENST00000502617.1
aminoadipate-semialdehyde dehydrogenase
chr9_+_108320392 0.08 ENST00000602661.1
ENST00000223528.2
ENST00000448551.2
ENST00000540160.1
fukutin
chr17_-_57229155 0.08 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr7_-_103848405 0.08 ENST00000447452.2
ENST00000545943.1
ENST00000297431.4
origin recognition complex, subunit 5
chr7_-_151217166 0.07 ENST00000496004.1
Ras homolog enriched in brain
chr5_-_150473127 0.07 ENST00000521001.1
TNFAIP3 interacting protein 1
chr3_+_49977894 0.07 ENST00000433811.1
RNA binding motif protein 6
chr1_-_232651312 0.07 ENST00000262861.4
signal-induced proliferation-associated 1 like 2
chr2_+_179318295 0.07 ENST00000442710.1
deafness, autosomal recessive 59
chr15_-_72521017 0.07 ENST00000561609.1
pyruvate kinase, muscle
chr7_-_54826869 0.06 ENST00000450622.1
Sec61 gamma subunit
chr12_-_118797475 0.06 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAO kinase 3
chr10_-_37891859 0.06 ENST00000544824.1
MT-RNR2-like 7
chr12_+_64173583 0.06 ENST00000261234.6
transmembrane protein 5
chr16_+_53412368 0.06 ENST00000565189.1
RP11-44F14.2
chr3_-_145940214 0.06 ENST00000481701.1
phospholipid scramblase 4
chr15_+_69854027 0.06 ENST00000498938.2
RP11-279F6.1
chr16_-_66864806 0.05 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
NEDD8 activating enzyme E1 subunit 1
chr5_-_159546396 0.05 ENST00000523662.1
ENST00000456329.3
ENST00000307063.7
PWWP domain containing 2A
chr6_-_26199471 0.05 ENST00000341023.1
histone cluster 1, H2ad
chr7_-_5998714 0.05 ENST00000539903.1
radial spoke head 10 homolog B (Chlamydomonas)
chr3_-_129513259 0.05 ENST00000329333.5
transmembrane and coiled-coil domain family 1
chr2_+_102953608 0.05 ENST00000311734.2
ENST00000409584.1
interleukin 1 receptor-like 1
chr7_-_54826920 0.05 ENST00000395535.3
ENST00000352861.4
Sec61 gamma subunit
chr2_-_55496174 0.05 ENST00000417363.1
ENST00000412530.1
ENST00000394600.3
ENST00000366137.2
ENST00000420637.1
mitochondrial translational initiation factor 2
chr21_-_35014027 0.05 ENST00000399442.1
ENST00000413017.2
ENST00000445393.1
ENST00000417979.1
ENST00000426935.1
ENST00000381540.3
ENST00000361534.2
ENST00000381554.3
crystallin, zeta (quinone reductase)-like 1
chr4_+_128554081 0.05 ENST00000335251.6
ENST00000296461.5
inturned planar cell polarity protein
chr17_-_62499334 0.05 ENST00000579996.1
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr8_+_22424551 0.04 ENST00000523348.1
sorbin and SH3 domain containing 3
chr7_-_65113280 0.04 ENST00000593865.1
Protein LOC100996407
chr8_-_82373809 0.04 ENST00000379071.2
fatty acid binding protein 9, testis
chr5_+_180682720 0.04 ENST00000599439.1
CDNA: FLJ23158 fis, clone LNG09623; Uncharacterized protein
chr10_-_90712520 0.04 ENST00000224784.6
actin, alpha 2, smooth muscle, aorta
chr18_+_32556892 0.04 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
microtubule-associated protein, RP/EB family, member 2
chr4_+_15471489 0.04 ENST00000424120.1
ENST00000413206.1
ENST00000438599.2
ENST00000511544.1
ENST00000512702.1
ENST00000507954.1
ENST00000515124.1
ENST00000503292.1
ENST00000503658.1
coiled-coil and C2 domain containing 2A
chr2_-_10587897 0.04 ENST00000405333.1
ENST00000443218.1
ornithine decarboxylase 1
chr5_+_118668846 0.04 ENST00000513374.1
tumor necrosis factor, alpha-induced protein 8
chr6_+_125524785 0.04 ENST00000392482.2
tumor protein D52-like 1
chrX_-_20074895 0.04 ENST00000543767.1
MAP7 domain containing 2
chr14_-_34420259 0.04 ENST00000250457.3
ENST00000547327.2
egl-9 family hypoxia-inducible factor 3
chr17_-_39216344 0.04 ENST00000391418.2
keratin associated protein 2-3
chr2_+_179317994 0.04 ENST00000375129.4
deafness, autosomal recessive 59
chr1_-_153518270 0.04 ENST00000354332.4
ENST00000368716.4
S100 calcium binding protein A4
chr8_+_76452097 0.04 ENST00000396423.2
hepatocyte nuclear factor 4, gamma
chr12_-_118796910 0.04 ENST00000541186.1
ENST00000539872.1
TAO kinase 3
chr11_-_62323702 0.04 ENST00000530285.1
AHNAK nucleoprotein
chr7_+_99717230 0.04 ENST00000262932.3
canopy FGF signaling regulator 4
chr10_-_116286656 0.04 ENST00000428430.1
ENST00000369266.3
ENST00000392952.3
actin binding LIM protein 1
chr12_+_122688090 0.04 ENST00000324189.4
ENST00000546192.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr3_+_119187785 0.04 ENST00000295588.4
ENST00000476573.1
protein O-glucosyltransferase 1
chr2_+_74648848 0.03 ENST00000409791.1
ENST00000426787.1
ENST00000348227.4
WD repeat domain 54
chr14_-_51027838 0.03 ENST00000555216.1
mitogen-activated protein kinase kinase kinase kinase 5
chr17_+_48823975 0.03 ENST00000513969.1
ENST00000503728.1
LUC7-like 3 (S. cerevisiae)
chr12_-_49245916 0.03 ENST00000552512.1
ENST00000551468.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
chr3_-_131221771 0.03 ENST00000510154.1
ENST00000507669.1
mitochondrial ribosomal protein L3
chr5_+_68860949 0.03 ENST00000507595.1
general transcription factor IIH, polypeptide 2C
chr21_+_34619079 0.03 ENST00000433395.2
AP000295.9
chr6_+_112408768 0.03 ENST00000368656.2
ENST00000604268.1
family with sequence similarity 229, member B
chr6_+_105404899 0.03 ENST00000345080.4
lin-28 homolog B (C. elegans)
chr1_+_219347203 0.03 ENST00000366927.3
lysophospholipase-like 1
chr6_-_76072719 0.03 ENST00000370020.1
filamin A interacting protein 1
chr20_+_43029911 0.03 ENST00000443598.2
ENST00000316099.4
ENST00000415691.2
hepatocyte nuclear factor 4, alpha
chr16_+_23652700 0.03 ENST00000300087.2
dynactin 5 (p25)
chr1_+_95616933 0.03 ENST00000604203.1
TMEM56-RWDD3 readthrough
chr1_-_168464875 0.03 ENST00000422253.1
RP5-968D22.3
chr3_-_149095652 0.03 ENST00000305366.3
transmembrane 4 L six family member 1
chr3_+_62936098 0.03 ENST00000475886.1
ENST00000465684.1
ENST00000465262.1
ENST00000468072.1
long intergenic non-protein coding RNA 698
chr16_-_23652570 0.02 ENST00000261584.4
partner and localizer of BRCA2
chr14_-_23395623 0.02 ENST00000556043.1
protein arginine methyltransferase 5
chr13_+_24844979 0.02 ENST00000454083.1
spermatogenesis associated 13
chr6_-_131291572 0.02 ENST00000529208.1
erythrocyte membrane protein band 4.1-like 2
chr13_+_78315466 0.02 ENST00000314070.5
ENST00000462234.1
SLAIN motif family, member 1
chr6_+_30848557 0.02 ENST00000460944.2
ENST00000324771.8
discoidin domain receptor tyrosine kinase 1
chr4_+_70894130 0.02 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
histatin 3
chr14_-_78083112 0.02 ENST00000216484.2
serine palmitoyltransferase, long chain base subunit 2
chr16_+_88636875 0.02 ENST00000569435.1
zinc finger CCCH-type containing 18
chrX_+_105937068 0.02 ENST00000324342.3
ring finger protein 128, E3 ubiquitin protein ligase
chr8_-_19459993 0.02 ENST00000454498.2
ENST00000520003.1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr7_-_112758589 0.02 ENST00000413744.1
ENST00000439551.1
ENST00000441359.1
long intergenic non-protein coding RNA 998
chr10_-_61900762 0.02 ENST00000355288.2
ankyrin 3, node of Ranvier (ankyrin G)
chr3_-_98619999 0.02 ENST00000449482.1
discoidin, CUB and LCCL domain containing 2
chr4_-_109541539 0.02 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34 antisense RNA 1 (head to head)
chr1_+_160709055 0.02 ENST00000368043.3
ENST00000368042.3
ENST00000458602.2
ENST00000458104.2
SLAM family member 7
chr2_-_175712270 0.02 ENST00000295497.7
ENST00000444394.1
chimerin 1
chr1_+_244515930 0.02 ENST00000366537.1
ENST00000308105.4
chromosome 1 open reading frame 100
chr13_+_73632897 0.02 ENST00000377687.4
Kruppel-like factor 5 (intestinal)
chr1_+_62439037 0.02 ENST00000545929.1
InaD-like (Drosophila)
chr11_+_113258495 0.02 ENST00000303941.3
ankyrin repeat and kinase domain containing 1
chr21_+_35014706 0.02 ENST00000399353.1
ENST00000444491.1
ENST00000381318.3
intersectin 1 (SH3 domain protein)
chr9_+_21440440 0.02 ENST00000276927.1
interferon, alpha 1
chr19_-_30199516 0.02 ENST00000591243.1
chromosome 19 open reading frame 12
chr21_+_35014783 0.02 ENST00000381291.4
ENST00000381285.4
ENST00000399367.3
ENST00000399352.1
ENST00000399355.2
ENST00000399349.1
intersectin 1 (SH3 domain protein)
chr6_-_26027480 0.02 ENST00000377364.3
histone cluster 1, H4b
chrX_+_11129388 0.02 ENST00000321143.4
ENST00000380763.3
ENST00000380762.4
holocytochrome c synthase
chr6_+_123038689 0.02 ENST00000354275.2
ENST00000368446.1
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr6_+_3259148 0.02 ENST00000419065.2
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
proteasome (prosome, macropain) assembly chaperone 4
chr4_-_153332886 0.02 ENST00000603841.1
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr19_+_42212501 0.02 ENST00000398599.4
carcinoembryonic antigen-related cell adhesion molecule 5
chr5_+_98109322 0.02 ENST00000513185.1
repulsive guidance molecule family member b
chr14_-_68159152 0.02 ENST00000554035.1
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
chr16_+_4606347 0.02 ENST00000444310.4
chromosome 16 open reading frame 96
chr2_+_12454437 0.01 ENST00000412606.1
AC096559.1
chr19_+_42212526 0.01 ENST00000598976.1
ENST00000435837.2
ENST00000221992.6
ENST00000405816.1
Uncharacterized protein
carcinoembryonic antigen-related cell adhesion molecule 5
chr10_-_69597828 0.01 ENST00000339758.7
DnaJ (Hsp40) homolog, subfamily C, member 12
chr11_-_104972158 0.01 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr13_+_19756173 0.01 ENST00000382988.2
RP11-408E5.4
chr16_+_333152 0.01 ENST00000219406.6
ENST00000404312.1
ENST00000456379.1
protein disulfide isomerase family A, member 2
chr9_-_98268883 0.01 ENST00000551630.1
ENST00000548420.1
patched 1
chr12_+_27932803 0.01 ENST00000381271.2
kelch-like family member 42
chr2_+_120436733 0.01 ENST00000401466.1
ENST00000424086.1
ENST00000272521.6
transmembrane protein 177
chr3_+_73110810 0.01 ENST00000533473.1
endogenous Bornavirus-like nucleoprotein 2
chr4_+_147096837 0.01 ENST00000296581.5
ENST00000502781.1
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr3_-_160823040 0.01 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr17_+_17082842 0.01 ENST00000579361.1
myosin phosphatase Rho interacting protein
chr18_+_3466248 0.01 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
chr9_-_139137648 0.01 ENST00000358701.5
quiescin Q6 sulfhydryl oxidase 2
chr9_-_125240235 0.01 ENST00000259357.2
olfactory receptor, family 1, subfamily J, member 1
chr12_-_118796971 0.01 ENST00000542902.1
TAO kinase 3
chr2_+_68962014 0.00 ENST00000467265.1
Rho GTPase activating protein 25
chr2_+_109204909 0.00 ENST00000393310.1
LIM and senescent cell antigen-like domains 1
chr1_+_84630574 0.00 ENST00000413538.1
ENST00000417530.1
protein kinase, cAMP-dependent, catalytic, beta
chr8_+_28748765 0.00 ENST00000355231.5
homeobox containing 1
chr20_+_57464200 0.00 ENST00000604005.1
GNAS complex locus
chr13_+_33160553 0.00 ENST00000315596.10
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr11_+_24518723 0.00 ENST00000336930.6
ENST00000529015.1
ENST00000533227.1
leucine zipper protein 2
chr3_+_57882024 0.00 ENST00000494088.1
sarcolemma associated protein
chr2_+_234627424 0.00 ENST00000373409.3
UDP glucuronosyltransferase 1 family, polypeptide A4
chr15_-_72563585 0.00 ENST00000287196.9
ENST00000260376.7
poly (ADP-ribose) polymerase family, member 6
chr16_+_31271274 0.00 ENST00000287497.8
ENST00000544665.3
integrin, alpha M (complement component 3 receptor 3 subunit)
chr5_+_137722255 0.00 ENST00000542866.1
lysine (K)-specific demethylase 3B
chr4_+_153021899 0.00 ENST00000509332.1
ENST00000504144.1
ENST00000499452.2
RP11-18H21.1
chr2_+_173686303 0.00 ENST00000397087.3
Rap guanine nucleotide exchange factor (GEF) 4
chr1_+_160709076 0.00 ENST00000359331.4
ENST00000495334.1
SLAM family member 7
chr11_-_31531121 0.00 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr11_+_31391381 0.00 ENST00000465995.1
ENST00000536040.1
DnaJ (Hsp40) homolog, subfamily C, member 24
chr14_+_100532771 0.00 ENST00000557153.1
Enah/Vasp-like
chr3_-_131221790 0.00 ENST00000512877.1
ENST00000264995.3
ENST00000511168.1
ENST00000425847.2
mitochondrial ribosomal protein L3
chr20_+_56964169 0.00 ENST00000475243.1
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr4_-_89951028 0.00 ENST00000506913.1
family with sequence similarity 13, member A
chr4_-_159956333 0.00 ENST00000434826.2
chromosome 4 open reading frame 45
chr1_+_145883868 0.00 ENST00000447947.2
G protein-coupled receptor 89C

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.0 0.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.1 GO:1902416 positive regulation of mRNA binding(GO:1902416)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.0 0.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.2 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)