Project

A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for LHX6

Z-value: 1.01

Motif logo

logo of

Transcription factors associated with LHX6

Gene Symbol Gene ID Gene Info
LHX6
ENSG00000106852.11 LIM homeobox 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX6hg19_v2_chr9_-_124990680_124990719-0.792.1e-01Click!

Activity profile of LHX6 motif

Sorted Z-values of LHX6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_5710919 1.77 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr7_+_37723336 1.75 ENST00000450180.1
GPR141
G protein-coupled receptor 141
chr12_-_56753858 1.68 ENST00000314128.4
ENST00000557235.1
ENST00000418572.2
STAT2
signal transducer and activator of transcription 2, 113kDa
chr11_-_102668879 1.05 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr11_-_33913708 0.97 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr11_-_121986923 0.83 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr6_+_29691198 0.77 ENST00000440587.2
ENST00000434407.2
HLA-F
major histocompatibility complex, class I, F
chr6_+_29691056 0.76 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
HLA-F
major histocompatibility complex, class I, F
chr6_+_30457244 0.76 ENST00000376630.4
HLA-E
major histocompatibility complex, class I, E
chr19_-_54663473 0.75 ENST00000222224.3
LENG1
leukocyte receptor cluster (LRC) member 1
chr10_+_6821545 0.59 ENST00000436383.1
LINC00707
long intergenic non-protein coding RNA 707
chr9_-_38424443 0.54 ENST00000377694.1
IGFBPL1
insulin-like growth factor binding protein-like 1
chr4_-_110736505 0.53 ENST00000609440.1
RP11-602N24.3
RP11-602N24.3
chr6_-_30684898 0.51 ENST00000422266.1
ENST00000416571.1
MDC1
mediator of DNA-damage checkpoint 1
chr3_-_42003613 0.49 ENST00000414606.1
ULK4
unc-51 like kinase 4
chr17_+_30089454 0.49 ENST00000577970.1
RP11-805L22.3
RP11-805L22.3
chr1_-_228613026 0.46 ENST00000366696.1
HIST3H3
histone cluster 3, H3
chr4_-_19458597 0.46 ENST00000505347.1
RP11-3J1.1
RP11-3J1.1
chr17_-_1532106 0.44 ENST00000301335.5
ENST00000382147.4
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr1_-_190446759 0.43 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr3_-_42003479 0.41 ENST00000420927.1
ULK4
unc-51 like kinase 4
chr16_+_31724618 0.38 ENST00000530881.1
ENST00000529515.1
ZNF720
zinc finger protein 720
chr11_+_67798090 0.38 ENST00000313468.5
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr14_-_76127519 0.37 ENST00000256319.6
C14orf1
chromosome 14 open reading frame 1
chr11_+_67798114 0.37 ENST00000453471.2
ENST00000528492.1
ENST00000526339.1
ENST00000525419.1
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr7_+_100209979 0.37 ENST00000493970.1
ENST00000379527.2
MOSPD3
motile sperm domain containing 3
chr6_-_167040731 0.36 ENST00000265678.4
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr7_+_100210133 0.36 ENST00000393950.2
ENST00000424091.2
MOSPD3
motile sperm domain containing 3
chr2_-_198540751 0.35 ENST00000429081.1
RFTN2
raftlin family member 2
chr17_-_1531635 0.35 ENST00000571650.1
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr16_+_55512742 0.34 ENST00000568715.1
ENST00000219070.4
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr21_-_22175341 0.34 ENST00000416768.1
ENST00000452561.1
ENST00000419299.1
ENST00000437238.1
LINC00320
long intergenic non-protein coding RNA 320
chr10_+_103986085 0.34 ENST00000370005.3
ELOVL3
ELOVL fatty acid elongase 3
chr17_+_74261413 0.34 ENST00000587913.1
UBALD2
UBA-like domain containing 2
chr11_-_133826852 0.34 ENST00000533871.2
ENST00000321016.8
IGSF9B
immunoglobulin superfamily, member 9B
chr12_+_64798826 0.34 ENST00000540203.1
XPOT
exportin, tRNA
chr6_+_34204642 0.33 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr14_-_99947121 0.32 ENST00000329331.3
ENST00000436070.2
SETD3
SET domain containing 3
chr11_+_57435441 0.31 ENST00000528177.1
ZDHHC5
zinc finger, DHHC-type containing 5
chr7_+_100209725 0.31 ENST00000223054.4
MOSPD3
motile sperm domain containing 3
chr20_+_32782375 0.31 ENST00000568305.1
ASIP
agouti signaling protein
chr19_+_7694623 0.30 ENST00000594797.1
ENST00000456958.3
ENST00000601406.1
PET100
PET100 homolog (S. cerevisiae)
chr19_-_42916499 0.30 ENST00000601189.1
ENST00000599211.1
LIPE
lipase, hormone-sensitive
chr4_+_158493642 0.30 ENST00000507108.1
ENST00000455598.1
ENST00000509450.1
RP11-364P22.1
RP11-364P22.1
chr17_-_73937028 0.29 ENST00000586631.2
FBF1
Fas (TNFRSF6) binding factor 1
chr1_-_232598163 0.28 ENST00000308942.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr12_-_95611149 0.28 ENST00000549499.1
ENST00000343958.4
ENST00000546711.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr14_+_100842735 0.28 ENST00000554998.1
ENST00000402312.3
ENST00000335290.6
ENST00000554175.1
WDR25
WD repeat domain 25
chr2_+_220143989 0.28 ENST00000336576.5
DNAJB2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr5_+_115358088 0.28 ENST00000600981.3
CTD-2287O16.3
CTD-2287O16.3
chr5_+_154181816 0.28 ENST00000518677.1
LARP1
La ribonucleoprotein domain family, member 1
chr2_+_220144052 0.28 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
DNAJB2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr6_+_122931366 0.27 ENST00000368452.2
ENST00000368448.1
ENST00000392490.1
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr21_-_22175450 0.27 ENST00000435279.2
LINC00320
long intergenic non-protein coding RNA 320
chr19_-_40931891 0.27 ENST00000357949.4
SERTAD1
SERTA domain containing 1
chr20_+_18488137 0.26 ENST00000450074.1
ENST00000262544.2
ENST00000336714.3
ENST00000377475.3
SEC23B
Sec23 homolog B (S. cerevisiae)
chr19_-_7694417 0.26 ENST00000358368.4
ENST00000534844.1
XAB2
XPA binding protein 2
chr19_+_12902289 0.26 ENST00000302754.4
JUNB
jun B proto-oncogene
chr17_+_72772621 0.26 ENST00000335464.5
ENST00000417024.2
ENST00000578764.1
ENST00000582773.1
ENST00000582330.1
TMEM104
transmembrane protein 104
chr2_+_201936458 0.26 ENST00000237889.4
NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr14_-_100842588 0.26 ENST00000556645.1
ENST00000556209.1
ENST00000556504.1
ENST00000556435.1
ENST00000554772.1
ENST00000553581.1
ENST00000553769.2
ENST00000554605.1
ENST00000557722.1
ENST00000553413.1
ENST00000553524.1
ENST00000358655.4
WARS
tryptophanyl-tRNA synthetase
chr9_+_71944241 0.26 ENST00000257515.8
FAM189A2
family with sequence similarity 189, member A2
chr14_-_52535712 0.26 ENST00000216286.5
ENST00000541773.1
NID2
nidogen 2 (osteonidogen)
chrX_-_47509887 0.26 ENST00000247161.3
ENST00000592066.1
ENST00000376983.3
ELK1
ELK1, member of ETS oncogene family
chr5_+_142149932 0.25 ENST00000274498.4
ARHGAP26
Rho GTPase activating protein 26
chr1_-_21620877 0.24 ENST00000527991.1
ECE1
endothelin converting enzyme 1
chr6_-_30585009 0.24 ENST00000376511.2
PPP1R10
protein phosphatase 1, regulatory subunit 10
chr12_-_22063787 0.24 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr1_+_44115814 0.24 ENST00000372396.3
KDM4A
lysine (K)-specific demethylase 4A
chr10_-_28571015 0.24 ENST00000375719.3
ENST00000375732.1
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr13_+_19756173 0.24 ENST00000382988.2
RP11-408E5.4
RP11-408E5.4
chr19_-_53400813 0.23 ENST00000595635.1
ENST00000594741.1
ENST00000597111.1
ENST00000593618.1
ENST00000597909.1
ZNF320
zinc finger protein 320
chr7_+_150929550 0.23 ENST00000482173.1
ENST00000495645.1
ENST00000035307.2
CHPF2
chondroitin polymerizing factor 2
chr10_+_13141441 0.23 ENST00000263036.5
OPTN
optineurin
chr4_+_144312659 0.23 ENST00000509992.1
GAB1
GRB2-associated binding protein 1
chr6_+_46661575 0.22 ENST00000450697.1
TDRD6
tudor domain containing 6
chr10_+_71561630 0.22 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
COL13A1
collagen, type XIII, alpha 1
chr22_+_42017459 0.22 ENST00000405878.1
XRCC6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr19_+_48949087 0.22 ENST00000598711.1
GRWD1
glutamate-rich WD repeat containing 1
chr11_+_67798363 0.22 ENST00000525628.1
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr3_-_47018219 0.22 ENST00000292314.2
ENST00000546280.1
CCDC12
coiled-coil domain containing 12
chr10_+_13141585 0.21 ENST00000378764.2
OPTN
optineurin
chr10_-_46168156 0.21 ENST00000374371.2
ENST00000335258.7
ZFAND4
zinc finger, AN1-type domain 4
chr20_+_54967409 0.21 ENST00000415828.1
ENST00000217109.4
ENST00000428552.1
CSTF1
cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr5_-_171881362 0.21 ENST00000519643.1
SH3PXD2B
SH3 and PX domains 2B
chr17_+_12569306 0.21 ENST00000425538.1
MYOCD
myocardin
chr19_+_19303008 0.21 ENST00000353145.1
ENST00000421262.3
ENST00000303088.4
ENST00000456252.3
ENST00000593273.1
RFXANK
regulatory factor X-associated ankyrin-containing protein
chr6_-_31125850 0.21 ENST00000507751.1
ENST00000448162.2
ENST00000502557.1
ENST00000503420.1
ENST00000507892.1
ENST00000507226.1
ENST00000513222.1
ENST00000503934.1
ENST00000396263.2
ENST00000508683.1
ENST00000428174.1
ENST00000448141.2
ENST00000507829.1
ENST00000455279.2
ENST00000376266.5
CCHCR1
coiled-coil alpha-helical rod protein 1
chr14_-_99947168 0.21 ENST00000331768.5
SETD3
SET domain containing 3
chr7_+_120590803 0.20 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
ING3
inhibitor of growth family, member 3
chr11_-_128894053 0.20 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr3_-_53164423 0.20 ENST00000467048.1
ENST00000394738.3
ENST00000296292.3
RFT1
RFT1 homolog (S. cerevisiae)
chr22_+_42017280 0.20 ENST00000402580.3
ENST00000428575.2
ENST00000359308.4
XRCC6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr16_-_55866997 0.20 ENST00000360526.3
ENST00000361503.4
CES1
carboxylesterase 1
chr17_-_72772462 0.20 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
NAT9
N-acetyltransferase 9 (GCN5-related, putative)
chr18_+_60190682 0.20 ENST00000588676.1
ZCCHC2
zinc finger, CCHC domain containing 2
chr9_+_34646624 0.20 ENST00000450095.2
ENST00000556278.1
GALT
GALT
galactose-1-phosphate uridylyltransferase
Uncharacterized protein
chr6_-_33385655 0.20 ENST00000440279.3
ENST00000607266.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr14_+_32798462 0.20 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr9_+_1050331 0.19 ENST00000382255.3
ENST00000382251.3
ENST00000412350.2
DMRT2
doublesex and mab-3 related transcription factor 2
chr10_+_97709725 0.19 ENST00000472454.2
RP11-248J23.6
Protein LOC100652732
chr6_-_30685214 0.19 ENST00000425072.1
MDC1
mediator of DNA-damage checkpoint 1
chr19_-_19302931 0.19 ENST00000444486.3
ENST00000514819.3
ENST00000585679.1
ENST00000162023.5
MEF2BNB-MEF2B
MEF2BNB
MEF2B
MEF2BNB-MEF2B readthrough
MEF2B neighbor
myocyte enhancer factor 2B
chr10_-_99205607 0.19 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
EXOSC1
exosome component 1
chr17_+_12569472 0.19 ENST00000343344.4
MYOCD
myocardin
chr11_+_57435219 0.18 ENST00000527985.1
ENST00000287169.3
ZDHHC5
zinc finger, DHHC-type containing 5
chr6_+_160542821 0.18 ENST00000366963.4
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr10_+_71562180 0.18 ENST00000517713.1
ENST00000522165.1
ENST00000520133.1
COL13A1
collagen, type XIII, alpha 1
chr4_-_113558079 0.18 ENST00000445203.2
C4orf21
chromosome 4 open reading frame 21
chrX_+_19362011 0.18 ENST00000379806.5
ENST00000545074.1
ENST00000540249.1
ENST00000423505.1
ENST00000417819.1
ENST00000422285.2
ENST00000355808.5
ENST00000379805.3
PDHA1
pyruvate dehydrogenase (lipoamide) alpha 1
chr5_+_174151536 0.17 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chr22_-_42017021 0.17 ENST00000263256.6
DESI1
desumoylating isopeptidase 1
chr17_+_80416050 0.17 ENST00000579198.1
ENST00000390006.4
ENST00000580296.1
NARF
nuclear prelamin A recognition factor
chr20_+_5731083 0.17 ENST00000445603.1
ENST00000442185.1
C20orf196
chromosome 20 open reading frame 196
chr6_-_33385870 0.17 ENST00000488034.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr16_-_66583994 0.17 ENST00000564917.1
TK2
thymidine kinase 2, mitochondrial
chr18_+_616672 0.17 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr6_-_33385902 0.17 ENST00000374500.5
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr12_-_91546926 0.17 ENST00000550758.1
DCN
decorin
chr3_-_157221357 0.17 ENST00000494677.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr22_+_42017123 0.16 ENST00000360079.3
XRCC6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr11_-_102651343 0.16 ENST00000279441.4
ENST00000539681.1
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr5_-_110848253 0.16 ENST00000505803.1
ENST00000502322.1
STARD4
StAR-related lipid transfer (START) domain containing 4
chr12_-_45270077 0.16 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NELL2
NEL-like 2 (chicken)
chr9_+_34646651 0.16 ENST00000378842.3
GALT
galactose-1-phosphate uridylyltransferase
chr6_+_36165133 0.16 ENST00000446974.1
ENST00000454960.1
BRPF3
bromodomain and PHD finger containing, 3
chrM_+_10758 0.16 ENST00000361381.2
MT-ND4
mitochondrially encoded NADH dehydrogenase 4
chr4_-_103749179 0.16 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr6_-_33385823 0.16 ENST00000494751.1
ENST00000374496.3
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr18_+_60190226 0.16 ENST00000269499.5
ZCCHC2
zinc finger, CCHC domain containing 2
chr12_-_49418407 0.16 ENST00000526209.1
KMT2D
lysine (K)-specific methyltransferase 2D
chr1_-_1709845 0.16 ENST00000341426.5
ENST00000344463.4
NADK
NAD kinase
chr1_-_13390765 0.16 ENST00000357367.2
PRAMEF8
PRAME family member 8
chr12_-_9760482 0.15 ENST00000229402.3
KLRB1
killer cell lectin-like receptor subfamily B, member 1
chr6_-_27880174 0.15 ENST00000303324.2
OR2B2
olfactory receptor, family 2, subfamily B, member 2
chr4_-_69111401 0.15 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr6_-_62996066 0.15 ENST00000281156.4
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr6_+_26402465 0.15 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1
butyrophilin, subfamily 3, member A1
chr19_+_46236509 0.15 ENST00000457052.2
AC074212.3
Uncharacterized protein
chr3_-_101039402 0.15 ENST00000193391.7
IMPG2
interphotoreceptor matrix proteoglycan 2
chr12_+_7014064 0.15 ENST00000443597.2
LRRC23
leucine rich repeat containing 23
chr6_-_167040693 0.14 ENST00000366863.2
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr15_-_44116873 0.14 ENST00000267812.3
MFAP1
microfibrillar-associated protein 1
chr10_+_13142225 0.14 ENST00000378747.3
OPTN
optineurin
chr6_+_26183958 0.14 ENST00000356530.3
HIST1H2BE
histone cluster 1, H2be
chr2_-_20551983 0.13 ENST00000442400.1
PUM2
pumilio RNA-binding family member 2
chr6_-_33385854 0.13 ENST00000488478.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr3_+_102153859 0.13 ENST00000306176.1
ENST00000466937.1
ZPLD1
zona pellucida-like domain containing 1
chr18_+_61143994 0.13 ENST00000382771.4
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr3_+_115342349 0.13 ENST00000393780.3
GAP43
growth associated protein 43
chr13_+_37006421 0.13 ENST00000255465.4
CCNA1
cyclin A1
chr22_+_17956618 0.13 ENST00000262608.8
CECR2
cat eye syndrome chromosome region, candidate 2
chr16_-_66584059 0.13 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
TK2
thymidine kinase 2, mitochondrial
chr10_+_71561649 0.13 ENST00000398978.3
ENST00000354547.3
ENST00000357811.3
COL13A1
collagen, type XIII, alpha 1
chr10_-_72142345 0.13 ENST00000373224.1
ENST00000446961.1
ENST00000358141.2
ENST00000357631.2
LRRC20
leucine rich repeat containing 20
chr17_+_66511540 0.12 ENST00000588188.2
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr1_+_15986364 0.12 ENST00000345034.1
RSC1A1
regulatory solute carrier protein, family 1, member 1
chr17_+_80416482 0.11 ENST00000309794.11
ENST00000345415.7
ENST00000457415.3
ENST00000584411.1
ENST00000412079.2
ENST00000577432.1
NARF
nuclear prelamin A recognition factor
chr17_+_42786051 0.11 ENST00000315005.3
DBF4B
DBF4 homolog B (S. cerevisiae)
chr20_+_35807512 0.11 ENST00000373622.5
RPN2
ribophorin II
chr8_-_7243080 0.11 ENST00000400156.4
ZNF705G
zinc finger protein 705G
chr3_+_129207033 0.11 ENST00000507221.1
IFT122
intraflagellar transport 122 homolog (Chlamydomonas)
chr17_+_73452695 0.11 ENST00000582186.1
ENST00000582455.1
ENST00000581252.1
ENST00000579208.1
KIAA0195
KIAA0195
chrX_+_15525426 0.11 ENST00000342014.6
BMX
BMX non-receptor tyrosine kinase
chr7_-_127983877 0.11 ENST00000415472.2
ENST00000478061.1
ENST00000223073.2
ENST00000459726.1
RBM28
RNA binding motif protein 28
chr20_+_35807449 0.11 ENST00000237530.6
RPN2
ribophorin II
chr3_-_157221128 0.11 ENST00000392833.2
ENST00000362010.2
VEPH1
ventricular zone expressed PH domain-containing 1
chr7_-_14029515 0.11 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ETV1
ets variant 1
chr19_-_14889349 0.11 ENST00000315576.3
ENST00000392967.2
ENST00000346057.1
ENST00000353876.1
ENST00000353005.1
EMR2
egf-like module containing, mucin-like, hormone receptor-like 2
chr6_+_53948328 0.11 ENST00000370876.2
MLIP
muscular LMNA-interacting protein
chr4_+_144354644 0.11 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr14_+_76127529 0.11 ENST00000556977.1
ENST00000557636.1
ENST00000286650.5
ENST00000298832.9
TTLL5
tubulin tyrosine ligase-like family, member 5
chr6_+_39760129 0.11 ENST00000274867.4
DAAM2
dishevelled associated activator of morphogenesis 2
chr17_-_47841485 0.11 ENST00000506156.1
ENST00000240364.2
FAM117A
family with sequence similarity 117, member A
chr8_+_92261516 0.11 ENST00000276609.3
ENST00000309536.2
SLC26A7
solute carrier family 26 (anion exchanger), member 7
chr1_-_48866517 0.11 ENST00000371841.1
SPATA6
spermatogenesis associated 6
chr7_+_149571045 0.11 ENST00000479613.1
ENST00000606024.1
ENST00000464662.1
ENST00000425642.2
ATP6V0E2
ATPase, H+ transporting V0 subunit e2
chr3_+_40498783 0.10 ENST00000338970.6
ENST00000396203.2
ENST00000416518.1
RPL14
ribosomal protein L14
chr3_+_156799587 0.10 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chr20_+_49126881 0.10 ENST00000371621.3
ENST00000541713.1
PTPN1
protein tyrosine phosphatase, non-receptor type 1
chr18_-_65184217 0.10 ENST00000310045.7
DSEL
dermatan sulfate epimerase-like
chr2_-_74619152 0.10 ENST00000440727.1
ENST00000409240.1
DCTN1
dynactin 1
chr20_-_50418947 0.10 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr11_-_35287243 0.10 ENST00000464522.2
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr1_+_100817262 0.10 ENST00000455467.1
CDC14A
cell division cycle 14A
chr13_+_37006398 0.10 ENST00000418263.1
CCNA1
cyclin A1
chr19_-_14606900 0.10 ENST00000393029.3
ENST00000393028.1
ENST00000393033.4
ENST00000345425.2
ENST00000586027.1
ENST00000591349.1
ENST00000587210.1
GIPC1
GIPC PDZ domain containing family, member 1
chr20_+_54967663 0.10 ENST00000452950.1
CSTF1
cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr4_-_89951028 0.10 ENST00000506913.1
FAM13A
family with sequence similarity 13, member A
chr6_-_49681235 0.10 ENST00000339139.4
CRISP2
cysteine-rich secretory protein 2
chr2_-_74618964 0.09 ENST00000417090.1
ENST00000409868.1
DCTN1
dynactin 1
chr3_-_99569821 0.09 ENST00000487087.1
FILIP1L
filamin A interacting protein 1-like
chr3_-_157221380 0.09 ENST00000468233.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr12_-_45269430 0.09 ENST00000395487.2
NELL2
NEL-like 2 (chicken)
chr12_+_7013897 0.09 ENST00000007969.8
ENST00000323702.5
LRRC23
leucine rich repeat containing 23
chr3_-_105588231 0.09 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr3_-_180397256 0.09 ENST00000442201.2
CCDC39
coiled-coil domain containing 39
chr17_-_4871085 0.09 ENST00000575142.1
ENST00000206020.3
SPAG7
sperm associated antigen 7
chr17_+_73452545 0.09 ENST00000314256.7
KIAA0195
KIAA0195
chr9_-_35103105 0.09 ENST00000452248.2
ENST00000356493.5
STOML2
stomatin (EPB72)-like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX6

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:2000564 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) CD8-positive, alpha-beta T cell proliferation(GO:0035740) protection from natural killer cell mediated cytotoxicity(GO:0042270) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.2 1.5 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.4 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.1 0.6 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.4 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 0.6 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.1 0.1 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 0.3 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.1 0.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.4 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.1 GO:0010877 lipid transport involved in lipid storage(GO:0010877)
0.1 0.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.3 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.1 0.3 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986) oncogene-induced cell senescence(GO:0090402)
0.1 0.1 GO:0070997 neuron death(GO:0070997)
0.1 0.2 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.1 0.3 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.1 0.1 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.3 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 1.8 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.3 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.2 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 1.0 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.3 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.3 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.3 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.7 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0061055 myotome development(GO:0061055)
0.0 0.1 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.0 0.2 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.4 GO:0032596 protein transport into membrane raft(GO:0032596)
0.0 0.2 GO:0001555 oocyte growth(GO:0001555)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.9 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 1.0 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.2 GO:0046836 glycolipid transport(GO:0046836)
0.0 0.2 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.3 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:1904179 positive regulation of adipose tissue development(GO:1904179)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.0 GO:0001897 cytolysis by symbiont of host cells(GO:0001897)
0.0 0.1 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.3 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.5 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.8 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.1 GO:1901142 insulin metabolic process(GO:1901142)
0.0 0.1 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.2 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 1.8 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.1 GO:0097646 positive regulation of protein kinase A signaling(GO:0010739) dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:0016198 axon choice point recognition(GO:0016198)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.6 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.6 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.3 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.0 0.2 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.3 GO:0035976 AP1 complex(GO:0035976)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 1.9 GO:0015030 Cajal body(GO:0015030)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 1.5 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0046979 TAP2 binding(GO:0046979)
0.1 0.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.8 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.3 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1 0.2 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.3 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1 0.2 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375)
0.1 0.6 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.3 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.3 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0008841 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.0 1.7 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.4 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.0 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.8 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 1.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.8 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.7 PID ATM PATHWAY ATM pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.7 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 1.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.9 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism