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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for MAFA

Z-value: 0.29

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Transcription factors associated with MAFA

Gene Symbol Gene ID Gene Info
ENSG00000182759.3 MAF bZIP transcription factor A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MAFAhg19_v2_chr8_-_144512576_1445125760.316.9e-01Click!

Activity profile of MAFA motif

Sorted Z-values of MAFA motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_118826999 0.15 ENST00000264031.2
uroplakin 2
chr19_-_4124079 0.12 ENST00000394867.4
ENST00000262948.5
mitogen-activated protein kinase kinase 2
chr16_+_58074069 0.12 ENST00000570065.1
matrix metallopeptidase 15 (membrane-inserted)
chr16_+_67312049 0.11 ENST00000565899.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr15_+_90744533 0.11 ENST00000411539.2
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr9_-_100000957 0.09 ENST00000366109.2
ENST00000607322.1
RP11-498P14.5
chr11_-_104817919 0.09 ENST00000533252.1
caspase 4, apoptosis-related cysteine peptidase
chr16_-_21436459 0.08 ENST00000448012.2
ENST00000504841.2
ENST00000419180.2
nuclear pore complex interacting protein family, member B3
chr7_-_150754935 0.08 ENST00000297518.4
cyclin-dependent kinase 5
chr16_+_22524844 0.08 ENST00000538606.1
ENST00000424340.1
ENST00000517539.1
ENST00000528249.1
nuclear pore complex interacting protein family, member B5
chr9_+_100000717 0.08 ENST00000375205.2
ENST00000357054.1
ENST00000395220.1
ENST00000375202.2
ENST00000411667.2
coiled-coil domain containing 180
chr7_+_100860949 0.07 ENST00000305105.2
zinc finger, HIT-type containing 1
chr8_-_89339705 0.07 ENST00000286614.6
matrix metallopeptidase 16 (membrane-inserted)
chr16_-_29415350 0.07 ENST00000524087.1
nuclear pore complex interacting protein family, member B11
chr3_+_52422899 0.07 ENST00000480649.1
dynein, axonemal, heavy chain 1
chr19_-_33182616 0.07 ENST00000592431.1
CTD-2538C1.2
chr16_+_56225248 0.07 ENST00000262493.6
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr10_+_102505954 0.07 ENST00000556085.1
ENST00000427256.1
paired box 2
chr1_+_200842083 0.07 ENST00000304244.2
G protein-coupled receptor 25
chr16_-_29517141 0.06 ENST00000550665.1
Uncharacterized protein
chr16_-_21868739 0.06 ENST00000415645.2
nuclear pore complex interacting protein family, member B4
chr8_+_85095769 0.06 ENST00000518566.1
RALY RNA binding protein-like
chr10_-_118897567 0.06 ENST00000369206.5
ventral anterior homeobox 1
chr11_-_66103932 0.06 ENST00000311320.4
Ras and Rab interactor 1
chrX_+_68725084 0.06 ENST00000252338.4
family with sequence similarity 155, member B
chr22_+_48972118 0.06 ENST00000358295.5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr10_-_49701686 0.06 ENST00000417247.2
Rho GTPase activating protein 22
chr9_-_130889990 0.06 ENST00000449878.1
prostaglandin E synthase 2
chr7_-_86849836 0.05 ENST00000455575.1
transmembrane protein 243, mitochondrial
chr19_+_54641444 0.05 ENST00000221232.5
ENST00000358389.3
CCR4-NOT transcription complex, subunit 3
chr10_-_102289611 0.05 ENST00000299166.4
ENST00000370320.4
ENST00000531258.1
ENST00000370322.1
ENST00000535773.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
SEC31 homolog B (S. cerevisiae)
chr11_-_66103867 0.05 ENST00000424433.2
Ras and Rab interactor 1
chr19_+_38880695 0.05 ENST00000587947.1
ENST00000338502.4
sprouty-related, EVH1 domain containing 3
chr8_+_85095553 0.05 ENST00000521268.1
RALY RNA binding protein-like
chr1_+_110754094 0.05 ENST00000369787.3
ENST00000413138.3
ENST00000438661.2
potassium voltage-gated channel, Shaw-related subfamily, member 4
chr15_+_90744745 0.05 ENST00000558051.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr11_+_777562 0.05 ENST00000530083.1
Protein LOC100506518
chr6_+_42896865 0.05 ENST00000372836.4
ENST00000394142.3
canopy FGF signaling regulator 3
chr20_-_30795511 0.05 ENST00000246229.4
pleiomorphic adenoma gene-like 2
chr7_-_155160629 0.05 ENST00000378120.5
B-cell acute lymphoblastic leukemia expressed
chr7_-_22234381 0.05 ENST00000458533.1
Rap guanine nucleotide exchange factor (GEF) 5
chr7_-_135412925 0.05 ENST00000354042.4
solute carrier family 13 (sodium/sulfate symporter), member 4
chr11_-_75380165 0.04 ENST00000304771.3
microtubule-associated protein 6
chr3_+_184016986 0.04 ENST00000417952.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr18_+_77623668 0.04 ENST00000316249.3
potassium voltage-gated channel, subfamily G, member 2
chrX_-_92928557 0.04 ENST00000373079.3
ENST00000475430.2
nucleosome assembly protein 1-like 3
chr13_-_103426081 0.04 ENST00000376022.1
ENST00000376021.4
testis expressed 30
chr17_-_76128488 0.04 ENST00000322914.3
transmembrane channel-like 6
chr1_-_38325256 0.04 ENST00000373036.4
metal-regulatory transcription factor 1
chr3_+_140770183 0.04 ENST00000310546.2
splA/ryanodine receptor domain and SOCS box containing 4
chr17_-_39316983 0.04 ENST00000390661.3
keratin associated protein 4-4
chr7_-_151433342 0.04 ENST00000433631.2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr19_+_6740888 0.04 ENST00000596673.1
thyroid hormone receptor interactor 10
chr22_-_28197486 0.04 ENST00000302326.4
meningioma (disrupted in balanced translocation) 1
chr5_-_94620239 0.04 ENST00000515393.1
multiple C2 domains, transmembrane 1
chr10_-_135171510 0.04 ENST00000278025.4
ENST00000368552.3
fucose mutarotase
chr20_-_43743790 0.04 ENST00000307971.4
ENST00000372789.4
WAP four-disulfide core domain 5
chr20_+_306221 0.04 ENST00000342665.2
SRY (sex determining region Y)-box 12
chr6_-_24489842 0.04 ENST00000230036.1
glycosylphosphatidylinositol specific phospholipase D1
chr5_+_138629628 0.04 ENST00000508689.1
ENST00000514528.1
matrin 3
chr19_+_33182823 0.03 ENST00000397061.3
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr7_-_73133959 0.03 ENST00000395155.3
ENST00000395154.3
ENST00000222812.3
ENST00000395156.3
syntaxin 1A (brain)
chr8_-_114389353 0.03 ENST00000343508.3
CUB and Sushi multiple domains 3
chr19_+_12949251 0.03 ENST00000251472.4
microtubule associated serine/threonine kinase 1
chr7_-_30029328 0.03 ENST00000425819.2
ENST00000409570.1
secernin 1
chr9_-_28670283 0.03 ENST00000379992.2
leucine rich repeat and Ig domain containing 2
chrX_-_153141434 0.03 ENST00000407935.2
ENST00000439496.1
L1 cell adhesion molecule
chr10_-_79397391 0.03 ENST00000286628.8
ENST00000406533.3
ENST00000354353.5
ENST00000404857.1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr19_+_36103631 0.03 ENST00000203166.5
ENST00000379045.2
HAUS augmin-like complex, subunit 5
chr17_+_38465441 0.03 ENST00000577646.1
ENST00000254066.5
retinoic acid receptor, alpha
chr7_-_100860851 0.03 ENST00000223127.3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr5_-_114505591 0.03 ENST00000508894.1
tripartite motif containing 36
chr11_-_93276514 0.03 ENST00000526869.1
single-pass membrane protein with coiled-coil domains 4
chr6_+_97372596 0.03 ENST00000369261.4
kelch-like family member 32
chr19_-_37958318 0.03 ENST00000316950.6
ENST00000591710.1
zinc finger protein 569
chr1_+_163039143 0.03 ENST00000531057.1
ENST00000527809.1
ENST00000367908.4
regulator of G-protein signaling 4
chr3_+_131100515 0.03 ENST00000537561.1
ENST00000359850.3
ENST00000521288.1
ENST00000502852.1
nudix (nucleoside diphosphate linked moiety X)-type motif 16
chrX_-_1511617 0.03 ENST00000381401.5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr1_+_221054584 0.03 ENST00000549319.1
H2.0-like homeobox
chr16_-_89119355 0.03 ENST00000537498.1
CTD-2555A7.2
chr19_+_21541732 0.03 ENST00000311015.3
zinc finger protein 738
chr7_+_142749417 0.02 ENST00000418316.1
olfactory receptor, family 6, subfamily V, member 1
chr5_+_60933634 0.02 ENST00000505642.1
chromosome 5 open reading frame 64
chr1_-_45956800 0.02 ENST00000538496.1
testis-specific kinase 2
chr2_+_85811525 0.02 ENST00000306384.4
vesicle-associated membrane protein 5
chr5_-_114505624 0.02 ENST00000513154.1
tripartite motif containing 36
chrX_-_153141783 0.02 ENST00000458029.1
L1 cell adhesion molecule
chr4_-_22517620 0.02 ENST00000502482.1
ENST00000334304.5
G protein-coupled receptor 125
chrX_-_53310791 0.02 ENST00000375365.2
IQ motif and Sec7 domain 2
chr15_-_90456114 0.02 ENST00000398333.3
C15orf38-AP3S2 readthrough
chr1_-_45956868 0.02 ENST00000451835.2
testis-specific kinase 2
chr13_-_103426112 0.02 ENST00000376032.4
ENST00000376029.3
testis expressed 30
chr11_-_70507901 0.02 ENST00000449833.2
ENST00000357171.3
ENST00000449116.2
SH3 and multiple ankyrin repeat domains 2
chr1_-_54872059 0.02 ENST00000371320.3
single stranded DNA binding protein 3
chrY_-_1461617 0.02 ENSTR0000381401.5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr6_-_74161977 0.02 ENST00000370318.1
ENST00000370315.3
Mab-21 domain containing 1
chr3_-_49823941 0.02 ENST00000321599.4
ENST00000395238.1
ENST00000468463.1
ENST00000460540.1
inositol hexakisphosphate kinase 1
chr10_-_135171178 0.02 ENST00000368551.1
fucose mutarotase
chr15_+_80696666 0.02 ENST00000303329.4
aryl-hydrocarbon receptor nuclear translocator 2
chr9_+_131549610 0.02 ENST00000223865.8
TBC1 domain family, member 13
chr4_-_10118348 0.02 ENST00000502702.1
WD repeat domain 1
chr10_-_118897806 0.02 ENST00000277905.2
ventral anterior homeobox 1
chr1_-_216978709 0.02 ENST00000360012.3
estrogen-related receptor gamma
chr1_-_13331692 0.02 ENST00000353410.5
ENST00000376173.3
PRAME family member 3
chr17_-_39781054 0.02 ENST00000463128.1
keratin 17
chr20_-_23066953 0.02 ENST00000246006.4
CD93 molecule
chr20_+_306177 0.02 ENST00000544632.1
SRY (sex determining region Y)-box 12
chr9_+_2621798 0.02 ENST00000382100.3
very low density lipoprotein receptor
chrX_-_65859096 0.01 ENST00000456230.2
ectodysplasin A2 receptor
chr10_-_79397479 0.01 ENST00000404771.3
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr5_-_179285785 0.01 ENST00000520698.1
ENST00000518235.1
ENST00000376931.2
ENST00000518219.1
ENST00000521333.1
ENST00000523084.1
chromosome 5 open reading frame 45
chr16_+_28996572 0.01 ENST00000360872.5
ENST00000566177.1
ENST00000354453.4
linker for activation of T cells
chr1_-_63782888 0.01 ENST00000436475.2
long intergenic non-protein coding RNA 466
chr9_-_127905736 0.01 ENST00000336505.6
ENST00000373549.4
suppressor of cancer cell invasion
chr11_+_72929319 0.01 ENST00000393597.2
ENST00000311131.2
purinergic receptor P2Y, G-protein coupled, 2
chr14_+_81421861 0.01 ENST00000298171.2
thyroid stimulating hormone receptor
chr11_+_72929402 0.01 ENST00000393596.2
purinergic receptor P2Y, G-protein coupled, 2
chr11_+_111411384 0.01 ENST00000375615.3
ENST00000525126.1
ENST00000436913.2
ENST00000533265.1
layilin
chr12_+_108525517 0.01 ENST00000332082.4
WSC domain containing 2
chr11_-_57518848 0.01 ENST00000436147.3
BTB (POZ) domain containing 18
chr5_+_138629337 0.01 ENST00000394805.3
ENST00000512876.1
ENST00000513678.1
matrin 3
chr16_-_87525651 0.01 ENST00000268616.4
zinc finger, CCHC domain containing 14
chr10_+_124221036 0.01 ENST00000368984.3
HtrA serine peptidase 1
chr2_+_191745535 0.01 ENST00000320717.3
glutaminase
chr5_-_39270725 0.01 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYN binding protein
chr11_-_57177586 0.01 ENST00000529411.1
Uncharacterized protein
chr12_-_22487618 0.01 ENST00000404299.3
ENST00000396037.4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr14_+_81421355 0.01 ENST00000541158.2
thyroid stimulating hormone receptor
chr19_-_51141196 0.01 ENST00000338916.4
synaptotagmin III
chr10_+_120967072 0.01 ENST00000392870.2
G protein-coupled receptor kinase 5
chr9_+_2621950 0.01 ENST00000382096.1
very low density lipoprotein receptor
chr5_+_179286013 0.01 ENST00000499601.2
Uncharacterized protein
chr12_-_105478339 0.01 ENST00000424857.2
ENST00000258494.9
aldehyde dehydrogenase 1 family, member L2
chr6_-_99797522 0.01 ENST00000389677.5
failed axon connections homolog (Drosophila)
chr16_+_28996364 0.00 ENST00000564277.1
linker for activation of T cells
chr17_+_25936862 0.00 ENST00000582410.1
kinase suppressor of ras 1
chr4_-_151936865 0.00 ENST00000535741.1
LPS-responsive vesicle trafficking, beach and anchor containing
chr11_+_107461948 0.00 ENST00000265840.7
ENST00000443271.2
ELMO/CED-12 domain containing 1
chr11_+_111412053 0.00 ENST00000530962.1
layilin
chr5_-_118324200 0.00 ENST00000515439.3
ENST00000510708.1
DTW domain containing 2
chr1_+_202091980 0.00 ENST00000367282.5
G protein-coupled receptor 37 like 1
chr12_+_54943134 0.00 ENST00000243052.3
phosphodiesterase 1B, calmodulin-dependent
chr16_-_46865047 0.00 ENST00000394806.2
chromosome 16 open reading frame 87
chr11_+_33563618 0.00 ENST00000526400.1
KIAA1549-like
chr6_+_22221010 0.00 ENST00000567753.1
RP11-524C21.2
chr2_+_102624977 0.00 ENST00000441002.1
interleukin 1 receptor, type II
chr15_-_23086394 0.00 ENST00000337435.4
non imprinted in Prader-Willi/Angelman syndrome 1
chrX_-_153141302 0.00 ENST00000361699.4
ENST00000543994.1
ENST00000370057.3
ENST00000538883.1
ENST00000361981.3
L1 cell adhesion molecule
chr17_-_41623009 0.00 ENST00000393664.2
ets variant 4
chr16_-_67514982 0.00 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr4_+_72053017 0.00 ENST00000351898.6
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr14_+_24605389 0.00 ENST00000382708.3
ENST00000561435.1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr1_+_156124162 0.00 ENST00000368282.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

Network of associatons between targets according to the STRING database.

First level regulatory network of MAFA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.0 GO:0044416 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.0 0.0 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 0.0 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.0 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.1 GO:0097169 AIM2 inflammasome complex(GO:0097169)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.0 0.0 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)