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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for MIXL1_GSX1_BSX_MEOX2_LHX4

Z-value: 0.50

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Transcription factors associated with MIXL1_GSX1_BSX_MEOX2_LHX4

Gene Symbol Gene ID Gene Info
MIXL1
ENSG00000185155.7 Mix paired-like homeobox
GSX1
ENSG00000169840.4 GS homeobox 1
BSX
ENSG00000188909.4 brain specific homeobox
MEOX2
ENSG00000106511.5 mesenchyme homeobox 2
LHX4
ENSG00000121454.4 LIM homeobox 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MEOX2hg19_v2_chr7_-_15726296_157264370.782.2e-01Click!
LHX4hg19_v2_chr1_+_180199393_1801994260.762.4e-01Click!
MIXL1hg19_v2_chr1_+_226411319_226411366-0.623.8e-01Click!

Activity profile of MIXL1_GSX1_BSX_MEOX2_LHX4 motif

Sorted Z-values of MIXL1_GSX1_BSX_MEOX2_LHX4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_66536248 0.61 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1
RP11-807H7.1
chr2_+_179318295 0.42 ENST00000442710.1
DFNB59
deafness, autosomal recessive 59
chr12_+_28410128 0.41 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr5_-_148929848 0.38 ENST00000504676.1
ENST00000515435.1
CSNK1A1
casein kinase 1, alpha 1
chr17_-_64225508 0.37 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr5_+_68860949 0.36 ENST00000507595.1
GTF2H2C
general transcription factor IIH, polypeptide 2C
chr17_-_57229155 0.36 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr7_-_99716914 0.35 ENST00000431404.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr16_+_53133070 0.33 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr5_+_31193847 0.31 ENST00000514738.1
ENST00000265071.2
CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr7_+_77428066 0.30 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
PHTF2
putative homeodomain transcription factor 2
chr1_-_242612779 0.29 ENST00000427495.1
PLD5
phospholipase D family, member 5
chr12_-_74686314 0.28 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
RP11-81H3.2
RP11-81H3.2
chr6_+_153552455 0.26 ENST00000392385.2
AL590867.1
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr13_-_41593425 0.26 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr5_-_142780280 0.25 ENST00000424646.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr6_-_116833500 0.25 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr10_-_36812323 0.24 ENST00000543053.1
NAMPTL
nicotinamide phosphoribosyltransferase-like
chr18_-_33709268 0.24 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr6_+_76330355 0.24 ENST00000483859.2
SENP6
SUMO1/sentrin specific peptidase 6
chr6_-_109702885 0.23 ENST00000504373.1
CD164
CD164 molecule, sialomucin
chr6_-_32157947 0.23 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr10_-_104866395 0.23 ENST00000458345.1
NT5C2
5'-nucleotidase, cytosolic II
chr2_-_136678123 0.23 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr15_-_37393406 0.22 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr17_-_39341594 0.22 ENST00000398472.1
KRTAP4-1
keratin associated protein 4-1
chr13_-_86373536 0.22 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chrX_+_107334895 0.22 ENST00000372232.3
ENST00000345734.3
ENST00000372254.3
ATG4A
autophagy related 4A, cysteine peptidase
chr1_-_242612726 0.21 ENST00000459864.1
PLD5
phospholipase D family, member 5
chrM_+_10464 0.21 ENST00000361335.1
MT-ND4L
mitochondrially encoded NADH dehydrogenase 4L
chr7_-_111424506 0.21 ENST00000450156.1
ENST00000494651.2
DOCK4
dedicator of cytokinesis 4
chr2_-_44550441 0.20 ENST00000420756.1
ENST00000444696.1
PREPL
prolyl endopeptidase-like
chr1_-_183538319 0.20 ENST00000420553.1
ENST00000419402.1
NCF2
neutrophil cytosolic factor 2
chr17_-_78194716 0.20 ENST00000576707.1
SGSH
N-sulfoglucosamine sulfohydrolase
chr14_+_20187174 0.19 ENST00000557414.1
OR4N2
olfactory receptor, family 4, subfamily N, member 2
chr4_+_183065793 0.19 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chr17_-_39156138 0.19 ENST00000391587.1
KRTAP3-2
keratin associated protein 3-2
chr8_+_38831683 0.19 ENST00000302495.4
HTRA4
HtrA serine peptidase 4
chrM_+_8366 0.19 ENST00000361851.1
MT-ATP8
mitochondrially encoded ATP synthase 8
chr7_-_33102399 0.18 ENST00000242210.7
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr2_-_55647057 0.18 ENST00000436346.1
CCDC88A
coiled-coil domain containing 88A
chr3_+_148447887 0.18 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr7_-_104909435 0.18 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr1_+_180601139 0.18 ENST00000367590.4
ENST00000367589.3
XPR1
xenotropic and polytropic retrovirus receptor 1
chr3_+_130569429 0.17 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr11_-_117748138 0.17 ENST00000527717.1
FXYD6
FXYD domain containing ion transport regulator 6
chr12_-_94673956 0.17 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr1_+_212475148 0.17 ENST00000537030.3
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr13_-_36788718 0.17 ENST00000317764.6
ENST00000379881.3
SOHLH2
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr12_-_15815626 0.16 ENST00000540613.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr6_-_52859046 0.16 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
GSTA4
glutathione S-transferase alpha 4
chr1_+_204494618 0.16 ENST00000367180.1
ENST00000391947.2
MDM4
Mdm4 p53 binding protein homolog (mouse)
chr12_-_25150409 0.16 ENST00000549262.1
C12orf77
chromosome 12 open reading frame 77
chr7_-_33102338 0.16 ENST00000610140.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr10_-_71169031 0.16 ENST00000373307.1
TACR2
tachykinin receptor 2
chr14_-_57960545 0.16 ENST00000526336.1
ENST00000216445.3
C14orf105
chromosome 14 open reading frame 105
chr6_-_32908792 0.16 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr9_+_22646189 0.15 ENST00000436786.1
RP11-399D6.2
RP11-399D6.2
chr4_-_89442940 0.15 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr7_-_143599207 0.15 ENST00000355951.2
ENST00000479870.1
ENST00000478172.1
FAM115A
family with sequence similarity 115, member A
chr11_-_111649015 0.15 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr13_+_110958124 0.15 ENST00000400163.2
COL4A2
collagen, type IV, alpha 2
chr4_-_76649546 0.15 ENST00000508510.1
ENST00000509561.1
ENST00000499709.2
ENST00000511868.1
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr7_-_77427676 0.15 ENST00000257663.3
TMEM60
transmembrane protein 60
chr11_-_129062093 0.14 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr7_-_111424462 0.14 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr14_-_57960456 0.14 ENST00000534126.1
ENST00000422976.2
C14orf105
chromosome 14 open reading frame 105
chr11_-_117747607 0.14 ENST00000540359.1
ENST00000539526.1
FXYD6
FXYD domain containing ion transport regulator 6
chr17_-_38928414 0.14 ENST00000335552.4
KRT26
keratin 26
chr8_-_90996459 0.14 ENST00000517337.1
ENST00000409330.1
NBN
nibrin
chr6_+_130339710 0.14 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr17_-_33390667 0.14 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr10_+_86184676 0.14 ENST00000543283.1
CCSER2
coiled-coil serine-rich protein 2
chr8_+_98900132 0.14 ENST00000520016.1
MATN2
matrilin 2
chr22_+_31002990 0.14 ENST00000423350.1
TCN2
transcobalamin II
chr4_+_76649753 0.13 ENST00000603759.1
USO1
USO1 vesicle transport factor
chr12_-_110937351 0.13 ENST00000552130.2
VPS29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr5_-_89770582 0.13 ENST00000316610.6
MBLAC2
metallo-beta-lactamase domain containing 2
chr10_+_24497704 0.13 ENST00000376456.4
ENST00000458595.1
KIAA1217
KIAA1217
chr1_-_68698197 0.13 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr8_+_42873548 0.13 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chr3_+_149191723 0.13 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr7_+_77428149 0.13 ENST00000415251.2
ENST00000275575.7
PHTF2
putative homeodomain transcription factor 2
chr2_-_17981462 0.13 ENST00000402989.1
ENST00000428868.1
SMC6
structural maintenance of chromosomes 6
chr14_+_57671888 0.13 ENST00000391612.1
AL391152.1
AL391152.1
chr2_-_228582709 0.13 ENST00000541617.1
ENST00000409456.2
ENST00000409287.1
ENST00000258403.3
SLC19A3
solute carrier family 19 (thiamine transporter), member 3
chr11_-_117747434 0.13 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD6
FXYD domain containing ion transport regulator 6
chr7_-_151217166 0.13 ENST00000496004.1
RHEB
Ras homolog enriched in brain
chr5_+_66300446 0.13 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr1_+_229440129 0.13 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chrX_+_95939638 0.12 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
DIAPH2
diaphanous-related formin 2
chr4_+_174089904 0.12 ENST00000265000.4
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr14_-_92247032 0.12 ENST00000556661.1
ENST00000553676.1
ENST00000554560.1
CATSPERB
catsper channel auxiliary subunit beta
chr8_+_101170563 0.12 ENST00000520508.1
ENST00000388798.2
SPAG1
sperm associated antigen 1
chr3_-_69129501 0.12 ENST00000540295.1
ENST00000415609.2
ENST00000361055.4
ENST00000349511.4
UBA3
ubiquitin-like modifier activating enzyme 3
chr12_+_20963632 0.12 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr12_+_1099675 0.12 ENST00000545318.2
ERC1
ELKS/RAB6-interacting/CAST family member 1
chr3_+_138340067 0.12 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr18_-_21891460 0.12 ENST00000357041.4
OSBPL1A
oxysterol binding protein-like 1A
chr4_+_169418195 0.12 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr17_-_62499334 0.11 ENST00000579996.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chrX_+_107334983 0.11 ENST00000457035.1
ENST00000545696.1
ATG4A
autophagy related 4A, cysteine peptidase
chr12_-_88974236 0.11 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG
KIT ligand
chr14_+_62164340 0.11 ENST00000557538.1
ENST00000539097.1
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chrX_-_73511908 0.11 ENST00000455395.1
FTX
FTX transcript, XIST regulator (non-protein coding)
chr12_+_16500599 0.11 ENST00000535309.1
ENST00000540056.1
ENST00000396209.1
ENST00000540126.1
MGST1
microsomal glutathione S-transferase 1
chr12_+_44229846 0.11 ENST00000551577.1
ENST00000266534.3
TMEM117
transmembrane protein 117
chr8_-_17533838 0.11 ENST00000400046.1
MTUS1
microtubule associated tumor suppressor 1
chrM_-_14670 0.11 ENST00000361681.2
MT-ND6
mitochondrially encoded NADH dehydrogenase 6
chr5_-_87516448 0.11 ENST00000511218.1
TMEM161B
transmembrane protein 161B
chr2_-_208031943 0.11 ENST00000421199.1
ENST00000457962.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chrX_-_71458802 0.11 ENST00000373657.1
ENST00000334463.3
ERCC6L
excision repair cross-complementing rodent repair deficiency, complementation group 6-like
chr2_-_190446738 0.10 ENST00000427419.1
ENST00000455320.1
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr19_-_7698599 0.10 ENST00000311069.5
PCP2
Purkinje cell protein 2
chr12_+_16500571 0.10 ENST00000543076.1
ENST00000396210.3
MGST1
microsomal glutathione S-transferase 1
chr14_+_67831576 0.10 ENST00000555876.1
EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr20_+_5987890 0.10 ENST00000378868.4
CRLS1
cardiolipin synthase 1
chr4_-_176733897 0.10 ENST00000393658.2
GPM6A
glycoprotein M6A
chr2_+_38152462 0.10 ENST00000354545.2
RMDN2
regulator of microtubule dynamics 2
chr3_+_136649311 0.10 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr21_+_25801041 0.10 ENST00000453784.2
ENST00000423581.1
AP000476.1
AP000476.1
chr10_-_115904361 0.10 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr12_+_32832203 0.10 ENST00000553257.1
ENST00000549701.1
ENST00000358214.5
ENST00000266481.6
ENST00000551476.1
ENST00000550154.1
ENST00000547312.1
ENST00000414834.2
ENST00000381000.4
ENST00000548750.1
DNM1L
dynamin 1-like
chr16_+_12059091 0.10 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr14_+_101359265 0.10 ENST00000599197.1
AL117190.3
Esophagus cancer-related gene-2 interaction susceptibility protein; Uncharacterized protein
chr2_+_109204743 0.10 ENST00000332345.6
LIMS1
LIM and senescent cell antigen-like domains 1
chrX_+_134654540 0.10 ENST00000370752.4
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr8_+_26150628 0.10 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr3_-_165555200 0.10 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr7_-_27169801 0.10 ENST00000511914.1
HOXA4
homeobox A4
chr7_-_99277610 0.10 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
CYP3A5
cytochrome P450, family 3, subfamily A, polypeptide 5
chr7_+_23719749 0.10 ENST00000409192.3
ENST00000344962.4
ENST00000409653.1
ENST00000409994.3
FAM221A
family with sequence similarity 221, member A
chr19_-_58485895 0.10 ENST00000314391.3
C19orf18
chromosome 19 open reading frame 18
chr10_+_118349920 0.10 ENST00000531984.1
PNLIPRP1
pancreatic lipase-related protein 1
chr6_+_168418553 0.10 ENST00000354419.2
ENST00000351261.3
KIF25
kinesin family member 25
chr16_-_3350614 0.09 ENST00000268674.2
TIGD7
tigger transposable element derived 7
chr14_+_101295638 0.09 ENST00000523671.2
MEG3
maternally expressed 3 (non-protein coding)
chr9_-_5830768 0.09 ENST00000381506.3
ERMP1
endoplasmic reticulum metallopeptidase 1
chr5_+_102200948 0.09 ENST00000511477.1
ENST00000506006.1
ENST00000509832.1
PAM
peptidylglycine alpha-amidating monooxygenase
chr12_+_20963647 0.09 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr1_+_205682497 0.09 ENST00000598338.1
AC119673.1
AC119673.1
chr17_+_78518617 0.09 ENST00000537330.1
ENST00000570891.1
RPTOR
regulatory associated protein of MTOR, complex 1
chr12_-_10978957 0.09 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr5_+_137722255 0.09 ENST00000542866.1
KDM3B
lysine (K)-specific demethylase 3B
chr4_-_109541539 0.09 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr6_+_41010293 0.09 ENST00000373161.1
ENST00000373158.2
ENST00000470917.1
TSPO2
translocator protein 2
chr5_-_95297534 0.09 ENST00000513343.1
ENST00000431061.2
ELL2
elongation factor, RNA polymerase II, 2
chr16_-_66864806 0.09 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
NAE1
NEDD8 activating enzyme E1 subunit 1
chr6_+_149887377 0.09 ENST00000367419.5
GINM1
glycoprotein integral membrane 1
chr7_-_35013217 0.09 ENST00000446375.1
DPY19L1
dpy-19-like 1 (C. elegans)
chr14_-_38064198 0.09 ENST00000250448.2
FOXA1
forkhead box A1
chr3_-_143567262 0.09 ENST00000474151.1
ENST00000316549.6
SLC9A9
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr9_-_75488984 0.09 ENST00000423171.1
ENST00000449235.1
ENST00000453787.1
RP11-151D14.1
RP11-151D14.1
chr15_-_55700457 0.09 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
CCPG1
cell cycle progression 1
chr2_+_170440844 0.09 ENST00000260970.3
ENST00000433207.1
ENST00000409714.3
ENST00000462903.1
PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr16_+_53483983 0.08 ENST00000544545.1
RBL2
retinoblastoma-like 2 (p130)
chr4_+_76649797 0.08 ENST00000538159.1
ENST00000514213.2
USO1
USO1 vesicle transport factor
chr12_+_107712173 0.08 ENST00000280758.5
ENST00000420571.2
BTBD11
BTB (POZ) domain containing 11
chr1_-_45956822 0.08 ENST00000372086.3
ENST00000341771.6
TESK2
testis-specific kinase 2
chr19_-_51522955 0.08 ENST00000358789.3
KLK10
kallikrein-related peptidase 10
chr9_+_67977438 0.08 ENST00000456982.1
RP11-195B21.3
Protein LOC644249
chr5_-_159846066 0.08 ENST00000519349.1
ENST00000520664.1
SLU7
SLU7 splicing factor homolog (S. cerevisiae)
chr2_-_61697862 0.08 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr10_-_33405600 0.08 ENST00000414308.1
RP11-342D11.3
RP11-342D11.3
chr2_+_200472779 0.08 ENST00000427045.1
ENST00000419243.1
AC093590.1
AC093590.1
chr1_-_159832438 0.08 ENST00000368100.1
VSIG8
V-set and immunoglobulin domain containing 8
chr16_-_66764119 0.08 ENST00000569320.1
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr4_-_89205879 0.08 ENST00000608933.1
ENST00000315194.4
ENST00000514204.1
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr5_+_140201183 0.08 ENST00000529619.1
ENST00000529859.1
ENST00000378126.3
PCDHA5
protocadherin alpha 5
chr12_+_16500037 0.08 ENST00000536371.1
ENST00000010404.2
MGST1
microsomal glutathione S-transferase 1
chr4_+_90033968 0.08 ENST00000317005.2
TIGD2
tigger transposable element derived 2
chr2_-_152118276 0.08 ENST00000409092.1
RBM43
RNA binding motif protein 43
chr7_-_92747269 0.08 ENST00000446617.1
ENST00000379958.2
SAMD9
sterile alpha motif domain containing 9
chr14_+_36295504 0.08 ENST00000216807.7
BRMS1L
breast cancer metastasis-suppressor 1-like
chr3_-_194188956 0.08 ENST00000256031.4
ENST00000446356.1
ATP13A3
ATPase type 13A3
chr21_-_39705323 0.08 ENST00000436845.1
AP001422.3
AP001422.3
chr6_+_4087664 0.08 ENST00000430835.2
C6orf201
chromosome 6 open reading frame 201
chr4_-_76944621 0.08 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr19_+_52772832 0.08 ENST00000593703.1
ENST00000601711.1
ENST00000599581.1
ZNF766
zinc finger protein 766
chr17_+_15604513 0.08 ENST00000481540.1
ZNF286A
Homo sapiens zinc finger protein 286A (ZNF286A), transcript variant 6, mRNA.
chrX_+_95939711 0.08 ENST00000373049.4
ENST00000324765.8
DIAPH2
diaphanous-related formin 2
chr5_+_66300464 0.08 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr4_-_87770416 0.08 ENST00000273905.6
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter), member 6
chr8_-_109260897 0.08 ENST00000521297.1
ENST00000519030.1
ENST00000521440.1
ENST00000518345.1
ENST00000519627.1
ENST00000220849.5
EIF3E
eukaryotic translation initiation factor 3, subunit E
chr1_-_68698222 0.08 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr4_+_165675197 0.07 ENST00000515485.1
RP11-294O2.2
RP11-294O2.2
chr4_-_155533787 0.07 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG
fibrinogen gamma chain
chr4_+_95128748 0.07 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr2_+_190541153 0.07 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ANKAR
ankyrin and armadillo repeat containing
chr8_-_42396185 0.07 ENST00000518717.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr8_-_19614810 0.07 ENST00000524213.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr9_+_125281420 0.07 ENST00000340750.1
OR1J4
olfactory receptor, family 1, subfamily J, member 4
chr18_-_21977748 0.07 ENST00000399441.4
ENST00000319481.3
OSBPL1A
oxysterol binding protein-like 1A
chr8_-_82373809 0.07 ENST00000379071.2
FABP9
fatty acid binding protein 9, testis
chr14_+_65016620 0.07 ENST00000298705.1
PPP1R36
protein phosphatase 1, regulatory subunit 36
chrX_-_106243451 0.07 ENST00000355610.4
ENST00000535534.1
MORC4
MORC family CW-type zinc finger 4
chr9_-_15250114 0.07 ENST00000507993.1
TTC39B
tetratricopeptide repeat domain 39B
chr7_+_138145076 0.07 ENST00000343526.4
TRIM24
tripartite motif containing 24
chr6_-_161695042 0.07 ENST00000366908.5
ENST00000366911.5
ENST00000366905.3
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr6_-_39693111 0.07 ENST00000373215.3
ENST00000538893.1
ENST00000287152.7
ENST00000373216.3
KIF6
kinesin family member 6

Network of associatons between targets according to the STRING database.

First level regulatory network of MIXL1_GSX1_BSX_MEOX2_LHX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.2 GO:2001190 peptide antigen assembly with MHC class II protein complex(GO:0002503) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.3 GO:0051697 protein delipidation(GO:0051697)
0.0 0.2 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.4 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.2 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.0 0.1 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0 0.1 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.1 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.6 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.2 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.0 GO:0034756 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759)
0.0 0.4 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.0 0.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.1 GO:0070839 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.4 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.1 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.2 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.0 GO:0042040 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.1 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.0 0.0 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:0018032 protein amidation(GO:0018032)
0.0 0.1 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.0 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.0 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.0 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.0 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.0 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.0 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.0 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.0 GO:2000426 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.0 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.0 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.2 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.1 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.0 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0 0.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.0 GO:0051257 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.0 0.0 GO:0015855 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.0 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.0 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.0 0.2 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.0 GO:0051598 meiotic recombination checkpoint(GO:0051598)
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.0 0.0 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.0 0.0 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.0 GO:1902997 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) astrocyte end-foot(GO:0097450)
0.0 0.4 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.2 GO:0032010 phagolysosome(GO:0032010)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.4 GO:0042627 chylomicron(GO:0042627)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.0 GO:0005715 late recombination nodule(GO:0005715)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.0 GO:0097224 sperm connecting piece(GO:0097224)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.2 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.1 0.2 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 0.3 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.2 GO:0016826 N-sulfoglucosamine sulfohydrolase activity(GO:0016250) hydrolase activity, acting on acid sulfur-nitrogen bonds(GO:0016826)
0.1 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.3 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.0 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.0 GO:0031862 prostanoid receptor binding(GO:0031862)
0.0 0.3 GO:0043295 glutathione binding(GO:0043295)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.0 GO:0019115 benzaldehyde dehydrogenase activity(GO:0019115)
0.0 0.0 GO:0015254 pyrimidine nucleobase transmembrane transporter activity(GO:0005350) glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.0 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.2 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.0 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling