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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for MSX2
Z-value: 0.73
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Transcription factors associated with MSX2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MSX2 | hg19_v2_chr5_+_174151536_174151610 | 0.70 | 3.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr15_+_41245160 Show fit | 0.89 |
ENST00000444189.2
ENST00000446533.3 |
ChaC, cation transport regulator homolog 1 (E. coli) |
|
| chr17_+_74261413 Show fit | 0.54 |
ENST00000587913.1
|
UBA-like domain containing 2 |
|
| chr17_-_43045439 Show fit | 0.50 |
ENST00000253407.3
|
complement component 1, q subcomponent-like 1 |
|
| chr1_-_228613026 Show fit | 0.41 |
ENST00000366696.1
|
histone cluster 3, H3 |
|
| chr7_+_100209979 Show fit | 0.36 |
ENST00000493970.1
ENST00000379527.2 |
motile sperm domain containing 3 |
|
| chr15_+_80351910 Show fit | 0.35 |
ENST00000261749.6
ENST00000561060.1 |
zinc finger, AN1-type domain 6 |
|
| chr17_+_74261277 Show fit | 0.34 |
ENST00000327490.6
|
UBA-like domain containing 2 |
|
| chr19_+_4007644 Show fit | 0.34 |
ENST00000262971.2
|
protein inhibitor of activated STAT, 4 |
|
| chr12_-_10022735 Show fit | 0.34 |
ENST00000228438.2
|
C-type lectin domain family 2, member B |
|
| chr7_+_100210133 Show fit | 0.33 |
ENST00000393950.2
ENST00000424091.2 |
motile sperm domain containing 3 |
Network of associatons between targets according to the STRING database.
First level regulatory network of MSX2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | GO:0006751 | glutathione catabolic process(GO:0006751) |
| 0.2 | 0.5 | GO:0061743 | motor learning(GO:0061743) maintenance of synapse structure(GO:0099558) |
| 0.0 | 0.4 | GO:0030242 | pexophagy(GO:0030242) |
| 0.0 | 0.4 | GO:0032460 | negative regulation of protein oligomerization(GO:0032460) |
| 0.1 | 0.3 | GO:0061357 | positive regulation of Wnt protein secretion(GO:0061357) |
| 0.1 | 0.3 | GO:0001560 | regulation of cell growth by extracellular stimulus(GO:0001560) |
| 0.0 | 0.3 | GO:1902231 | positive regulation of keratinocyte apoptotic process(GO:1902174) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 0.0 | 0.3 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.0 | 0.3 | GO:0035090 | maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199) |
| 0.1 | 0.2 | GO:0042938 | dipeptide transport(GO:0042938) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0044301 | climbing fiber(GO:0044301) |
| 0.1 | 0.4 | GO:0034272 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272) |
| 0.0 | 0.4 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.0 | 0.2 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 0.0 | 0.2 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.0 | 0.1 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.0 | 0.1 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.9 | GO:0003839 | gamma-glutamylcyclotransferase activity(GO:0003839) |
| 0.0 | 0.3 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.0 | 0.3 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
| 0.0 | 0.3 | GO:0050694 | galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694) |
| 0.1 | 0.2 | GO:0047536 | 2-aminoadipate transaminase activity(GO:0047536) |
| 0.0 | 0.2 | GO:0015563 | uptake transmembrane transporter activity(GO:0015563) |
| 0.0 | 0.2 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.0 | 0.2 | GO:0070569 | uridylyltransferase activity(GO:0070569) |
| 0.0 | 0.2 | GO:0005537 | mannose binding(GO:0005537) |
| 0.0 | 0.1 | GO:0008892 | guanine deaminase activity(GO:0008892) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.0 | 0.4 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.0 | 0.1 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.0 | 0.1 | REACTOME OPSINS | Genes involved in Opsins |