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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for NHLH1

Z-value: 1.25

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Transcription factors associated with NHLH1

Gene Symbol Gene ID Gene Info
NHLH1
ENSG00000171786.5 nescient helix-loop-helix 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NHLH1hg19_v2_chr1_+_160336851_1603368680.653.5e-01Click!

Activity profile of NHLH1 motif

Sorted Z-values of NHLH1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_7005785 1.43 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr11_-_64764435 0.91 ENST00000534177.1
ENST00000301887.4
BATF2
basic leucine zipper transcription factor, ATF-like 2
chr14_-_37051798 0.77 ENST00000258829.5
NKX2-8
NK2 homeobox 8
chr4_+_89299994 0.76 ENST00000264346.7
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr4_+_89299885 0.68 ENST00000380265.5
ENST00000273960.3
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr19_+_35521572 0.64 ENST00000262631.5
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chr3_-_45187843 0.63 ENST00000296129.1
ENST00000425231.2
CDCP1
CUB domain containing protein 1
chr16_+_77246337 0.56 ENST00000563157.1
SYCE1L
synaptonemal complex central element protein 1-like
chr19_+_35521616 0.55 ENST00000595652.1
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chr6_-_134861089 0.53 ENST00000606039.1
RP11-557H15.4
RP11-557H15.4
chr20_-_23669590 0.52 ENST00000217423.3
CST4
cystatin S
chr6_+_126112001 0.52 ENST00000392477.2
NCOA7
nuclear receptor coactivator 7
chr15_+_90735145 0.49 ENST00000559792.1
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr7_-_100808843 0.47 ENST00000249330.2
VGF
VGF nerve growth factor inducible
chr17_-_54991369 0.46 ENST00000537230.1
TRIM25
tripartite motif containing 25
chr19_-_40730820 0.46 ENST00000513948.1
CNTD2
cyclin N-terminal domain containing 2
chr10_-_101380121 0.45 ENST00000370495.4
SLC25A28
solute carrier family 25 (mitochondrial iron transporter), member 28
chr5_+_49962772 0.45 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr2_+_196522032 0.45 ENST00000418005.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr10_+_102758105 0.44 ENST00000429732.1
LZTS2
leucine zipper, putative tumor suppressor 2
chr17_+_38171614 0.43 ENST00000583218.1
ENST00000394149.3
CSF3
colony stimulating factor 3 (granulocyte)
chr16_-_89268070 0.41 ENST00000562855.2
SLC22A31
solute carrier family 22, member 31
chr4_-_80994210 0.40 ENST00000403729.2
ANTXR2
anthrax toxin receptor 2
chr14_-_101053739 0.39 ENST00000554140.1
BEGAIN
brain-enriched guanylate kinase-associated
chr19_+_1286097 0.39 ENST00000215368.2
EFNA2
ephrin-A2
chr1_+_113217309 0.38 ENST00000544796.1
ENST00000369644.1
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr7_+_130794846 0.37 ENST00000421797.2
MKLN1
muskelin 1, intracellular mediator containing kelch motifs
chr1_-_47184745 0.37 ENST00000544071.1
EFCAB14
EF-hand calcium binding domain 14
chr6_-_38607673 0.37 ENST00000481247.1
BTBD9
BTB (POZ) domain containing 9
chr19_+_35521699 0.36 ENST00000415950.3
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chrX_-_47004437 0.36 ENST00000276062.8
NDUFB11
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
chr17_+_74261413 0.35 ENST00000587913.1
UBALD2
UBA-like domain containing 2
chr11_-_6341724 0.35 ENST00000530979.1
PRKCDBP
protein kinase C, delta binding protein
chr6_-_43596899 0.35 ENST00000307126.5
ENST00000452781.1
GTPBP2
GTP binding protein 2
chr19_+_4304685 0.34 ENST00000601006.1
FSD1
fibronectin type III and SPRY domain containing 1
chr2_+_8822113 0.34 ENST00000396290.1
ENST00000331129.3
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr14_+_64971438 0.33 ENST00000555321.1
ZBTB1
zinc finger and BTB domain containing 1
chr12_-_54779511 0.33 ENST00000551109.1
ENST00000546970.1
ZNF385A
zinc finger protein 385A
chr17_-_54991395 0.33 ENST00000316881.4
TRIM25
tripartite motif containing 25
chr17_+_80193644 0.32 ENST00000582946.1
SLC16A3
solute carrier family 16 (monocarboxylate transporter), member 3
chr5_-_94620239 0.32 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chr12_+_122064673 0.31 ENST00000537188.1
ORAI1
ORAI calcium release-activated calcium modulator 1
chr19_-_17445613 0.31 ENST00000159087.4
ANO8
anoctamin 8
chr20_-_31172598 0.30 ENST00000201961.2
C20orf112
chromosome 20 open reading frame 112
chr20_+_49348109 0.30 ENST00000396039.1
PARD6B
par-6 family cell polarity regulator beta
chr1_+_161692449 0.30 ENST00000367946.3
ENST00000367945.1
ENST00000336830.5
ENST00000367944.3
ENST00000392158.1
FCRLB
Fc receptor-like B
chr20_-_35274548 0.29 ENST00000262866.4
SLA2
Src-like-adaptor 2
chr19_+_41107249 0.29 ENST00000396819.3
LTBP4
latent transforming growth factor beta binding protein 4
chr17_+_39382900 0.29 ENST00000377721.3
ENST00000455970.2
KRTAP9-2
keratin associated protein 9-2
chr7_-_100808394 0.29 ENST00000445482.2
VGF
VGF nerve growth factor inducible
chr11_-_10830463 0.29 ENST00000527419.1
ENST00000530211.1
ENST00000530702.1
ENST00000524932.1
ENST00000532570.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr11_-_6341844 0.29 ENST00000303927.3
PRKCDBP
protein kinase C, delta binding protein
chr2_-_175202151 0.28 ENST00000595354.1
AC018470.1
Uncharacterized protein FLJ46347
chr3_-_5229982 0.28 ENST00000600805.1
AC026202.1
Uncharacterized protein
chr12_-_113658826 0.28 ENST00000546692.1
IQCD
IQ motif containing D
chr9_-_131940526 0.27 ENST00000372491.2
IER5L
immediate early response 5-like
chr16_+_330581 0.27 ENST00000219409.3
ARHGDIG
Rho GDP dissociation inhibitor (GDI) gamma
chr4_+_75311019 0.27 ENST00000502307.1
AREG
amphiregulin
chr6_-_160148356 0.27 ENST00000401980.3
ENST00000545162.1
SOD2
superoxide dismutase 2, mitochondrial
chr19_+_39989580 0.26 ENST00000596614.1
ENST00000205143.4
DLL3
delta-like 3 (Drosophila)
chr15_-_56209306 0.26 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
NEDD4
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr19_-_38743878 0.26 ENST00000587515.1
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr12_-_54813229 0.26 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chrX_-_45710920 0.25 ENST00000456532.1
RP5-1158E12.3
RP5-1158E12.3
chr14_+_102027688 0.25 ENST00000510508.4
ENST00000359323.3
DIO3
deiodinase, iodothyronine, type III
chr2_-_232791038 0.25 ENST00000295440.2
ENST00000409852.1
NPPC
natriuretic peptide C
chr7_-_138720763 0.25 ENST00000275766.1
ZC3HAV1L
zinc finger CCCH-type, antiviral 1-like
chr6_+_145118873 0.25 ENST00000432686.1
ENST00000417142.1
UTRN
utrophin
chr22_-_50964849 0.25 ENST00000543927.1
ENST00000423348.1
SCO2
SCO2 cytochrome c oxidase assembly protein
chr4_+_75310851 0.25 ENST00000395748.3
ENST00000264487.2
AREG
amphiregulin
chr6_+_31895467 0.25 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr12_-_74686314 0.25 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
RP11-81H3.2
RP11-81H3.2
chr22_-_36850991 0.25 ENST00000442579.1
RP5-1119A7.14
RP5-1119A7.14
chr9_-_100459639 0.25 ENST00000375128.4
XPA
xeroderma pigmentosum, complementation group A
chr6_+_31895480 0.24 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2
CFB
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr1_+_113217345 0.24 ENST00000357443.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr8_+_86376081 0.24 ENST00000285379.5
CA2
carbonic anhydrase II
chr22_+_19705928 0.24 ENST00000383045.3
ENST00000438754.2
SEPT5
septin 5
chr19_-_40732594 0.24 ENST00000430325.2
ENST00000433940.1
CNTD2
cyclin N-terminal domain containing 2
chr1_-_33336414 0.24 ENST00000373471.3
ENST00000609187.1
FNDC5
fibronectin type III domain containing 5
chr12_-_72057638 0.24 ENST00000552037.1
ENST00000378743.3
ZFC3H1
zinc finger, C3H1-type containing
chr20_-_48770244 0.23 ENST00000371650.5
ENST00000371652.4
ENST00000557021.1
TMEM189
transmembrane protein 189
chr17_+_48638371 0.23 ENST00000360761.4
ENST00000352832.5
ENST00000354983.4
CACNA1G
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr19_-_47104118 0.23 ENST00000593888.1
ENST00000602017.1
AC011551.3
PPP5D1
Uncharacterized protein
PPP5 tetratricopeptide repeat domain containing 1
chr2_-_102003987 0.23 ENST00000324768.5
CREG2
cellular repressor of E1A-stimulated genes 2
chr14_+_90863364 0.23 ENST00000447653.3
ENST00000553542.1
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr4_-_54930790 0.23 ENST00000263921.3
CHIC2
cysteine-rich hydrophobic domain 2
chr19_+_13228917 0.23 ENST00000586171.1
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr17_+_7338737 0.23 ENST00000323206.1
ENST00000396568.1
TMEM102
transmembrane protein 102
chr4_-_41216619 0.23 ENST00000508676.1
ENST00000506352.1
ENST00000295974.8
APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr17_-_31620006 0.22 ENST00000225823.2
ASIC2
acid-sensing (proton-gated) ion channel 2
chr1_-_244013384 0.22 ENST00000366539.1
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr1_-_197744763 0.22 ENST00000422998.1
DENND1B
DENN/MADD domain containing 1B
chr17_-_71228357 0.22 ENST00000583024.1
ENST00000403627.3
ENST00000405159.3
ENST00000581110.1
FAM104A
family with sequence similarity 104, member A
chr4_+_153457404 0.22 ENST00000604157.1
ENST00000594836.1
MIR4453
microRNA 4453
chr1_+_150039877 0.22 ENST00000419023.1
VPS45
vacuolar protein sorting 45 homolog (S. cerevisiae)
chr2_+_58655461 0.22 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1
long intergenic non-protein coding RNA 1122
chr20_+_30193083 0.22 ENST00000376112.3
ENST00000376105.3
ID1
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
chr5_-_95297534 0.22 ENST00000513343.1
ENST00000431061.2
ELL2
elongation factor, RNA polymerase II, 2
chr18_-_51750948 0.22 ENST00000583046.1
ENST00000398398.2
MBD2
methyl-CpG binding domain protein 2
chr19_-_19051103 0.22 ENST00000542541.2
ENST00000433218.2
HOMER3
homer homolog 3 (Drosophila)
chr17_-_27278445 0.21 ENST00000268756.3
ENST00000584685.1
PHF12
PHD finger protein 12
chr12_-_72057571 0.21 ENST00000548100.1
ZFC3H1
zinc finger, C3H1-type containing
chr9_-_4679419 0.21 ENST00000609131.1
ENST00000607997.1
RP11-6J24.6
RP11-6J24.6
chr2_+_10442993 0.21 ENST00000423674.1
ENST00000307845.3
HPCAL1
hippocalcin-like 1
chr6_+_146056706 0.20 ENST00000603994.1
RP3-466P17.1
RP3-466P17.1
chr7_-_100171270 0.20 ENST00000538735.1
SAP25
Sin3A-associated protein, 25kDa
chr11_-_10829851 0.20 ENST00000532082.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr17_-_73401728 0.20 ENST00000316804.5
ENST00000316615.5
GRB2
growth factor receptor-bound protein 2
chr1_-_226065330 0.20 ENST00000436966.1
TMEM63A
transmembrane protein 63A
chr12_-_113658892 0.20 ENST00000299732.2
ENST00000416617.2
IQCD
IQ motif containing D
chr20_-_48770174 0.20 ENST00000341698.2
TMEM189-UBE2V1
TMEM189-UBE2V1 readthrough
chr5_-_169816638 0.20 ENST00000521859.1
ENST00000274629.4
KCNMB1
potassium large conductance calcium-activated channel, subfamily M, beta member 1
chr3_-_133614597 0.19 ENST00000285208.4
ENST00000460865.3
RAB6B
RAB6B, member RAS oncogene family
chr9_-_127905736 0.19 ENST00000336505.6
ENST00000373549.4
SCAI
suppressor of cancer cell invasion
chr9_+_101569944 0.19 ENST00000375011.3
GALNT12
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12)
chr12_+_57984965 0.19 ENST00000540759.2
ENST00000551772.1
ENST00000550465.1
ENST00000354947.5
PIP4K2C
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr16_+_1756162 0.19 ENST00000250894.4
ENST00000356010.5
MAPK8IP3
mitogen-activated protein kinase 8 interacting protein 3
chr17_-_16395455 0.19 ENST00000409083.3
FAM211A
family with sequence similarity 211, member A
chr7_+_72848092 0.19 ENST00000344575.3
FZD9
frizzled family receptor 9
chr15_+_74833518 0.19 ENST00000346246.5
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chrX_-_19905703 0.19 ENST00000397821.3
SH3KBP1
SH3-domain kinase binding protein 1
chr17_+_74261277 0.19 ENST00000327490.6
UBALD2
UBA-like domain containing 2
chr1_-_91487806 0.19 ENST00000361321.5
ZNF644
zinc finger protein 644
chrX_-_84634737 0.19 ENST00000262753.4
POF1B
premature ovarian failure, 1B
chr17_-_56606639 0.19 ENST00000579371.1
SEPT4
septin 4
chr20_-_30433396 0.19 ENST00000375978.3
FOXS1
forkhead box S1
chr13_+_49550015 0.19 ENST00000492622.2
FNDC3A
fibronectin type III domain containing 3A
chr9_+_110045418 0.19 ENST00000419616.1
RAD23B
RAD23 homolog B (S. cerevisiae)
chr1_-_47134085 0.19 ENST00000371937.4
ENST00000574428.1
ENST00000329231.4
ATPAF1
ATP synthase mitochondrial F1 complex assembly factor 1
chr18_+_9913977 0.19 ENST00000400000.2
ENST00000340541.4
VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr21_-_46293586 0.18 ENST00000445724.2
ENST00000397887.3
PTTG1IP
pituitary tumor-transforming 1 interacting protein
chr1_+_150039787 0.18 ENST00000535106.1
VPS45
vacuolar protein sorting 45 homolog (S. cerevisiae)
chr17_-_31204124 0.18 ENST00000579584.1
ENST00000318217.5
ENST00000583621.1
MYO1D
myosin ID
chr2_+_23608064 0.18 ENST00000486442.1
KLHL29
kelch-like family member 29
chr3_+_159481988 0.18 ENST00000472451.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr5_+_176873446 0.18 ENST00000507881.1
PRR7
proline rich 7 (synaptic)
chr1_-_85155939 0.18 ENST00000603677.1
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr12_+_52404270 0.18 ENST00000552049.1
ENST00000546756.1
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr2_-_178937478 0.18 ENST00000286063.6
PDE11A
phosphodiesterase 11A
chr20_+_49348081 0.18 ENST00000371610.2
PARD6B
par-6 family cell polarity regulator beta
chr12_-_6579808 0.18 ENST00000535180.1
ENST00000400911.3
VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr5_-_59064458 0.18 ENST00000502575.1
ENST00000507116.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr11_-_64512273 0.18 ENST00000377497.3
ENST00000377487.1
ENST00000430645.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr1_-_92351666 0.17 ENST00000465892.2
ENST00000417833.2
TGFBR3
transforming growth factor, beta receptor III
chr2_+_233734994 0.17 ENST00000331342.2
C2orf82
chromosome 2 open reading frame 82
chr2_+_7005959 0.17 ENST00000442639.1
RSAD2
radical S-adenosyl methionine domain containing 2
chr10_-_27529779 0.17 ENST00000426079.1
ACBD5
acyl-CoA binding domain containing 5
chr3_-_172428959 0.17 ENST00000475381.1
ENST00000538775.1
ENST00000273512.3
ENST00000543711.1
NCEH1
neutral cholesterol ester hydrolase 1
chr8_-_98290087 0.17 ENST00000322128.3
TSPYL5
TSPY-like 5
chr7_-_77045617 0.17 ENST00000257626.7
GSAP
gamma-secretase activating protein
chr14_-_64971288 0.17 ENST00000394715.1
ZBTB25
zinc finger and BTB domain containing 25
chr17_-_56606705 0.17 ENST00000317268.3
SEPT4
septin 4
chr3_+_96533621 0.17 ENST00000542517.1
ENST00000506569.1
EPHA6
EPH receptor A6
chr19_+_39989535 0.17 ENST00000356433.5
DLL3
delta-like 3 (Drosophila)
chr2_-_233352531 0.17 ENST00000304546.1
ECEL1
endothelin converting enzyme-like 1
chr7_-_105925367 0.17 ENST00000354289.4
NAMPT
nicotinamide phosphoribosyltransferase
chr13_-_26625169 0.17 ENST00000319420.3
SHISA2
shisa family member 2
chr19_+_17416609 0.17 ENST00000602206.1
MRPL34
mitochondrial ribosomal protein L34
chr19_-_49944806 0.17 ENST00000221485.3
SLC17A7
solute carrier family 17 (vesicular glutamate transporter), member 7
chr17_+_4981535 0.17 ENST00000318833.3
ZFP3
ZFP3 zinc finger protein
chr21_+_38071430 0.17 ENST00000290399.6
SIM2
single-minded family bHLH transcription factor 2
chr3_-_68981685 0.16 ENST00000495737.1
ENST00000295569.7
FAM19A4
family with sequence similarity 19 (chemokine (C-C motif)-like), member A4
chr5_+_176873789 0.16 ENST00000323249.3
ENST00000502922.1
PRR7
proline rich 7 (synaptic)
chr14_-_24584138 0.16 ENST00000558280.1
ENST00000561028.1
NRL
neural retina leucine zipper
chr1_-_52344416 0.16 ENST00000544028.1
NRD1
nardilysin (N-arginine dibasic convertase)
chr21_+_34442439 0.16 ENST00000382348.1
ENST00000333063.5
OLIG1
oligodendrocyte transcription factor 1
chr12_-_118406777 0.16 ENST00000339824.5
KSR2
kinase suppressor of ras 2
chr16_+_11439286 0.16 ENST00000312499.5
ENST00000576027.1
RMI2
RecQ mediated genome instability 2
chr7_+_7811992 0.16 ENST00000406829.1
RPA3-AS1
RPA3 antisense RNA 1
chr19_+_46001697 0.16 ENST00000451287.2
ENST00000324688.4
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr10_+_105036909 0.16 ENST00000369849.4
INA
internexin neuronal intermediate filament protein, alpha
chr4_-_168155730 0.16 ENST00000502330.1
ENST00000357154.3
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr2_+_196521845 0.16 ENST00000359634.5
ENST00000412905.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr17_-_56606664 0.16 ENST00000580844.1
SEPT4
septin 4
chr2_+_16080659 0.16 ENST00000281043.3
MYCN
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr2_+_47168313 0.15 ENST00000319190.5
ENST00000394850.2
ENST00000536057.1
TTC7A
tetratricopeptide repeat domain 7A
chr11_+_62556596 0.15 ENST00000526546.1
TMEM179B
transmembrane protein 179B
chr3_-_78719376 0.15 ENST00000495961.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr19_-_45737469 0.15 ENST00000413988.1
EXOC3L2
exocyst complex component 3-like 2
chr2_-_73511407 0.15 ENST00000520530.2
FBXO41
F-box protein 41
chr1_-_19536744 0.15 ENST00000375267.2
ENST00000375217.2
ENST00000375226.2
ENST00000375254.3
UBR4
ubiquitin protein ligase E3 component n-recognin 4
chr1_+_157963063 0.15 ENST00000360089.4
ENST00000368173.3
ENST00000392272.2
KIRREL
kin of IRRE like (Drosophila)
chr17_-_79792909 0.15 ENST00000330261.4
ENST00000570394.1
PPP1R27
protein phosphatase 1, regulatory subunit 27
chr1_-_11107280 0.15 ENST00000400897.3
ENST00000400898.3
MASP2
mannan-binding lectin serine peptidase 2
chr1_+_20915409 0.15 ENST00000375071.3
CDA
cytidine deaminase
chr6_-_30712313 0.15 ENST00000376377.2
ENST00000259874.5
IER3
immediate early response 3
chr1_+_39456895 0.15 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
AKIRIN1
akirin 1
chr19_+_1941117 0.15 ENST00000255641.8
CSNK1G2
casein kinase 1, gamma 2
chrX_+_107069063 0.15 ENST00000262843.6
MID2
midline 2
chr17_+_66255310 0.15 ENST00000448504.2
ARSG
arylsulfatase G
chr16_+_3014269 0.14 ENST00000575885.1
ENST00000571007.1
ENST00000319500.6
KREMEN2
kringle containing transmembrane protein 2
chr17_-_73401567 0.14 ENST00000392562.1
GRB2
growth factor receptor-bound protein 2
chr6_-_75915757 0.14 ENST00000322507.8
COL12A1
collagen, type XII, alpha 1
chr1_+_161185032 0.14 ENST00000367992.3
ENST00000289902.1
FCER1G
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
chr2_+_191045656 0.14 ENST00000443551.2
C2orf88
chromosome 2 open reading frame 88
chr1_+_27113963 0.14 ENST00000430292.1
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chrX_-_134049262 0.14 ENST00000370783.3
MOSPD1
motile sperm domain containing 1
chr8_-_17270809 0.14 ENST00000180173.5
ENST00000521857.1
MTMR7
myotubularin related protein 7
chr12_+_121088291 0.14 ENST00000351200.2
CABP1
calcium binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of NHLH1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.4 1.4 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1 0.4 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.1 0.2 GO:0098876 Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.1 0.5 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.4 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1 0.5 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.1 0.2 GO:0042938 dipeptide transport(GO:0042938)
0.1 0.2 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.1 0.3 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1 0.2 GO:1903413 cellular response to bile acid(GO:1903413)
0.1 0.5 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.1 0.3 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.1 0.6 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.2 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.1 0.4 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.3 GO:0003069 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1 0.2 GO:0007468 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.2 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.4 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.3 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.1 GO:0033024 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894) positive regulation of mast cell cytokine production(GO:0032765) mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.2 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.0 0.3 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.3 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 0.1 GO:0032804 viral protein processing(GO:0019082) negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.3 GO:0003419 growth plate cartilage chondrocyte proliferation(GO:0003419)
0.0 0.1 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.0 1.0 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.2 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.2 GO:1990523 bone regeneration(GO:1990523)
0.0 0.2 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of negative chemotaxis(GO:0050925)
0.0 0.9 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.2 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.0 0.2 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.1 GO:0006311 meiotic gene conversion(GO:0006311)
0.0 0.1 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.1 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.0 0.1 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.1 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.3 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.0 0.1 GO:0043311 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.0 0.2 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154) positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.0 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.2 GO:0018032 protein amidation(GO:0018032)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.0 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0008057 eye pigment granule organization(GO:0008057)
0.0 0.1 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.2 GO:1903243 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.0 0.3 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.0 0.0 GO:1904378 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.2 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.2 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.8 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.3 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.6 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:2000397 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.1 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936) granulocyte colony-stimulating factor production(GO:0071611) regulation of granulocyte colony-stimulating factor production(GO:0071655) positive regulation of granulocyte colony-stimulating factor production(GO:0071657) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
0.0 0.2 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.1 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.1 GO:0035900 response to isolation stress(GO:0035900)
0.0 0.4 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.1 GO:0060214 endocardium formation(GO:0060214)
0.0 0.1 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.0 0.1 GO:0046836 glycolipid transport(GO:0046836)
0.0 0.0 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.1 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.1 GO:0035864 response to potassium ion(GO:0035864)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.0 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.2 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.1 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838)
0.0 0.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.4 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.1 GO:0060503 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.1 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.0 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.0 GO:0034699 response to luteinizing hormone(GO:0034699)
0.0 0.3 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.2 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.0 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.0 0.5 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.1 GO:2001038 regulation of cellular response to drug(GO:2001038)
0.0 0.1 GO:1904526 regulation of microtubule binding(GO:1904526)
0.0 0.0 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.0 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.0 0.1 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.2 GO:0030057 desmosome(GO:0030057)
0.1 0.3 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.3 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.1 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.2 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0042565 RNA nuclear export complex(GO:0042565)
0.0 0.6 GO:0097227 sperm annulus(GO:0097227)
0.0 0.1 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.6 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.2 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0 0.7 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.4 1.4 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.3 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.2 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.1 0.2 GO:0001855 complement component C4b binding(GO:0001855)
0.0 0.2 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.3 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.8 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.4 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.3 GO:0050815 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.0 0.3 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.1 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.1 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.1 GO:0030395 lactose binding(GO:0030395)
0.0 0.1 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.2 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.2 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.4 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 1.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.0 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.0 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.0 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.0 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.6 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.3 PID FOXO PATHWAY FoxO family signaling
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.5 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.8 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.6 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins