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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for NKX2-4

Z-value: 1.52

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Transcription factors associated with NKX2-4

Gene Symbol Gene ID Gene Info
NKX2-4
ENSG00000125816.4 NK2 homeobox 4

Activity profile of NKX2-4 motif

Sorted Z-values of NKX2-4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_38177575 1.41 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
RMDN2
regulator of microtubule dynamics 2
chr14_+_32414059 1.30 ENST00000553330.1
RP11-187E13.1
Uncharacterized protein
chr4_-_155533787 1.00 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG
fibrinogen gamma chain
chr11_-_104035088 0.98 ENST00000302251.5
PDGFD
platelet derived growth factor D
chr16_+_12059091 0.98 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr3_+_118905564 0.78 ENST00000460625.1
UPK1B
uroplakin 1B
chr4_+_72204755 0.75 ENST00000512686.1
ENST00000340595.3
SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr19_-_40440533 0.75 ENST00000221347.6
FCGBP
Fc fragment of IgG binding protein
chr4_+_155484155 0.75 ENST00000509493.1
FGB
fibrinogen beta chain
chr4_+_90033968 0.74 ENST00000317005.2
TIGD2
tigger transposable element derived 2
chr12_-_71533055 0.73 ENST00000552128.1
TSPAN8
tetraspanin 8
chr2_+_109065634 0.73 ENST00000409821.1
GCC2
GRIP and coiled-coil domain containing 2
chr6_-_73935163 0.72 ENST00000370388.3
KHDC1L
KH homology domain containing 1-like
chr1_+_95583479 0.70 ENST00000455656.1
ENST00000604534.1
TMEM56
RP11-57H12.6
transmembrane protein 56
TMEM56-RWDD3 readthrough
chr3_-_49066811 0.70 ENST00000442157.1
ENST00000326739.4
IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr3_-_112329110 0.67 ENST00000479368.1
CCDC80
coiled-coil domain containing 80
chr1_-_197036364 0.65 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr2_-_36779411 0.62 ENST00000406220.1
AC007401.2
Uncharacterized protein
chr17_-_38574169 0.62 ENST00000423485.1
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr10_-_18944123 0.61 ENST00000606425.1
RP11-139J15.7
Uncharacterized protein
chr17_-_19062424 0.60 ENST00000399083.1
AC007952.6
Uncharacterized protein
chr16_+_3062457 0.59 ENST00000445369.2
CLDN9
claudin 9
chr18_+_9136758 0.58 ENST00000383440.2
ENST00000262126.4
ENST00000577992.1
ANKRD12
ankyrin repeat domain 12
chr22_+_25465786 0.54 ENST00000401395.1
KIAA1671
KIAA1671
chr2_+_120687335 0.54 ENST00000544261.1
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr2_-_85828867 0.53 ENST00000425160.1
TMEM150A
transmembrane protein 150A
chr10_+_99332529 0.52 ENST00000455090.1
ANKRD2
ankyrin repeat domain 2 (stretch responsive muscle)
chr12_+_123237321 0.51 ENST00000280557.6
ENST00000455982.2
DENR
density-regulated protein
chr15_+_75315896 0.50 ENST00000342932.3
ENST00000564923.1
ENST00000569562.1
ENST00000568649.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr1_+_61869748 0.49 ENST00000357977.5
NFIA
nuclear factor I/A
chr13_-_43566301 0.49 ENST00000398762.3
ENST00000313640.7
ENST00000313624.7
EPSTI1
epithelial stromal interaction 1 (breast)
chrX_-_84363974 0.48 ENST00000395409.3
ENST00000332921.5
ENST00000509231.1
SATL1
spermidine/spermine N1-acetyl transferase-like 1
chr15_+_34394257 0.47 ENST00000397766.2
PGBD4
piggyBac transposable element derived 4
chr9_-_3469181 0.47 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr11_+_107992518 0.47 ENST00000527942.1
ACAT1
acetyl-CoA acetyltransferase 1
chr2_+_161993465 0.47 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr6_+_27925019 0.46 ENST00000244623.1
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr7_+_134551583 0.46 ENST00000435928.1
CALD1
caldesmon 1
chr2_-_220025263 0.45 ENST00000457600.1
NHEJ1
nonhomologous end-joining factor 1
chr21_+_40177143 0.45 ENST00000360214.3
ETS2
v-ets avian erythroblastosis virus E26 oncogene homolog 2
chr11_-_506316 0.45 ENST00000532055.1
ENST00000531540.1
RNH1
ribonuclease/angiogenin inhibitor 1
chr14_+_64680854 0.45 ENST00000458046.2
SYNE2
spectrin repeat containing, nuclear envelope 2
chr12_-_12503156 0.45 ENST00000543314.1
ENST00000396349.3
MANSC1
MANSC domain containing 1
chr7_+_65552756 0.44 ENST00000450043.1
AC068533.7
AC068533.7
chr11_-_105892937 0.44 ENST00000301919.4
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
MSANTD4
Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
chr7_-_17980091 0.44 ENST00000409389.1
ENST00000409604.1
ENST00000428135.3
SNX13
sorting nexin 13
chr15_-_31523036 0.43 ENST00000559094.1
ENST00000558388.2
RP11-16E12.2
RP11-16E12.2
chr2_+_53994927 0.43 ENST00000295304.4
CHAC2
ChaC, cation transport regulator homolog 2 (E. coli)
chrX_+_70443050 0.43 ENST00000361726.6
GJB1
gap junction protein, beta 1, 32kDa
chr11_+_33037652 0.42 ENST00000311388.3
DEPDC7
DEP domain containing 7
chr14_-_23451845 0.41 ENST00000262713.2
AJUBA
ajuba LIM protein
chr3_+_30647994 0.41 ENST00000295754.5
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr5_+_175298573 0.40 ENST00000512824.1
CPLX2
complexin 2
chr11_+_61976137 0.40 ENST00000244930.4
SCGB2A1
secretoglobin, family 2A, member 1
chr17_+_4634705 0.40 ENST00000575284.1
ENST00000573708.1
ENST00000293777.5
MED11
mediator complex subunit 11
chr9_-_86432547 0.39 ENST00000376365.3
ENST00000376371.2
GKAP1
G kinase anchoring protein 1
chr12_-_58329819 0.39 ENST00000551421.1
RP11-620J15.3
RP11-620J15.3
chr6_+_42018251 0.39 ENST00000372978.3
ENST00000494547.1
ENST00000456846.2
ENST00000372982.4
ENST00000472818.1
ENST00000372977.3
TAF8
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr18_-_28622699 0.38 ENST00000360428.4
DSC3
desmocollin 3
chr19_-_42758040 0.38 ENST00000593944.1
ERF
Ets2 repressor factor
chr15_+_36887069 0.38 ENST00000566807.1
ENST00000567389.1
ENST00000562877.1
C15orf41
chromosome 15 open reading frame 41
chr4_-_100242549 0.37 ENST00000305046.8
ENST00000394887.3
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
chr1_-_89458287 0.37 ENST00000370485.2
CCBL2
cysteine conjugate-beta lyase 2
chr19_-_12444491 0.37 ENST00000293725.5
ZNF563
zinc finger protein 563
chr18_-_28622774 0.37 ENST00000434452.1
DSC3
desmocollin 3
chr9_+_140119618 0.37 ENST00000359069.2
C9orf169
chromosome 9 open reading frame 169
chr1_+_161136180 0.36 ENST00000352210.5
ENST00000367999.4
ENST00000544598.1
ENST00000535223.1
ENST00000432542.2
PPOX
protoporphyrinogen oxidase
chr15_-_63448973 0.36 ENST00000462430.1
RPS27L
ribosomal protein S27-like
chr17_-_5138099 0.35 ENST00000571800.1
ENST00000574081.1
ENST00000399600.4
ENST00000574297.1
SCIMP
SLP adaptor and CSK interacting membrane protein
chr4_+_3388057 0.35 ENST00000538395.1
RGS12
regulator of G-protein signaling 12
chr14_-_81408093 0.35 ENST00000555265.1
CEP128
centrosomal protein 128kDa
chr4_-_682769 0.34 ENST00000507165.1
MFSD7
major facilitator superfamily domain containing 7
chr6_-_149806105 0.34 ENST00000389942.5
ENST00000416573.2
ENST00000542614.1
ENST00000409806.3
ZC3H12D
zinc finger CCCH-type containing 12D
chr14_-_23451467 0.34 ENST00000555074.1
ENST00000361265.4
RP11-298I3.5
AJUBA
RP11-298I3.5
ajuba LIM protein
chr1_+_64239657 0.34 ENST00000371080.1
ENST00000371079.1
ROR1
receptor tyrosine kinase-like orphan receptor 1
chr8_+_97597148 0.34 ENST00000521590.1
SDC2
syndecan 2
chr7_-_86848933 0.34 ENST00000423734.1
TMEM243
transmembrane protein 243, mitochondrial
chr7_-_55606346 0.33 ENST00000545390.1
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr2_+_205410723 0.33 ENST00000358768.2
ENST00000351153.1
ENST00000349953.3
PARD3B
par-3 family cell polarity regulator beta
chr6_-_28303901 0.33 ENST00000439158.1
ENST00000446474.1
ENST00000414431.1
ENST00000344279.6
ENST00000453745.1
ZSCAN31
zinc finger and SCAN domain containing 31
chr9_-_36258326 0.33 ENST00000447283.2
GNE
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr12_-_102591604 0.33 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr5_-_78808617 0.32 ENST00000282260.6
ENST00000508576.1
ENST00000535690.1
HOMER1
homer homolog 1 (Drosophila)
chr4_+_96012614 0.32 ENST00000264568.4
BMPR1B
bone morphogenetic protein receptor, type IB
chr1_+_196788887 0.32 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
CFHR1
CFHR2
complement factor H-related 1
complement factor H-related 2
chr3_+_186158169 0.31 ENST00000435548.1
ENST00000421006.1
RP11-78H24.1
RP11-78H24.1
chrX_-_154563889 0.31 ENST00000369449.2
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr1_-_70671216 0.31 ENST00000370952.3
LRRC40
leucine rich repeat containing 40
chr14_-_96830207 0.31 ENST00000359933.4
ATG2B
autophagy related 2B
chr12_+_27863706 0.31 ENST00000081029.3
ENST00000538315.1
ENST00000542791.1
MRPS35
mitochondrial ribosomal protein S35
chr12_+_50451331 0.31 ENST00000228468.4
ASIC1
acid-sensing (proton-gated) ion channel 1
chr17_+_19122674 0.31 ENST00000436914.1
AC106017.1
Uncharacterized protein
chr2_-_3521518 0.31 ENST00000382093.5
ADI1
acireductone dioxygenase 1
chr4_-_68411275 0.31 ENST00000273853.6
CENPC
centromere protein C
chr12_+_50451462 0.31 ENST00000447966.2
ASIC1
acid-sensing (proton-gated) ion channel 1
chr8_-_65730127 0.31 ENST00000522106.1
RP11-1D12.2
RP11-1D12.2
chr7_-_102252589 0.30 ENST00000520042.1
RASA4
RAS p21 protein activator 4
chr19_+_41856816 0.30 ENST00000539627.1
TMEM91
transmembrane protein 91
chr22_-_18923655 0.30 ENST00000438924.1
ENST00000457083.1
ENST00000420436.1
ENST00000334029.2
ENST00000357068.6
PRODH
proline dehydrogenase (oxidase) 1
chr6_+_37225540 0.30 ENST00000373491.3
TBC1D22B
TBC1 domain family, member 22B
chr4_+_169418195 0.29 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr17_+_18996287 0.29 ENST00000399091.1
ENST00000443876.1
ENST00000428928.1
AC007952.5
Uncharacterized protein ENSP00000382042
chr3_+_189349162 0.29 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63
tumor protein p63
chr8_+_104310661 0.29 ENST00000522566.1
FZD6
frizzled family receptor 6
chr15_+_42694573 0.29 ENST00000397200.4
ENST00000569827.1
CAPN3
calpain 3, (p94)
chr14_+_96829886 0.29 ENST00000556095.1
GSKIP
GSK3B interacting protein
chr11_-_44972418 0.29 ENST00000525680.1
ENST00000528290.1
ENST00000530035.1
TP53I11
tumor protein p53 inducible protein 11
chr6_+_26158343 0.29 ENST00000377777.4
ENST00000289316.2
HIST1H2BD
histone cluster 1, H2bd
chr11_+_35965531 0.28 ENST00000528989.1
ENST00000524419.1
ENST00000315571.5
LDLRAD3
low density lipoprotein receptor class A domain containing 3
chr12_+_133757995 0.28 ENST00000536435.2
ENST00000228289.5
ENST00000541211.2
ENST00000500625.3
ENST00000539248.2
ENST00000542711.2
ENST00000536899.2
ENST00000542986.2
ENST00000537565.1
ENST00000541975.2
ZNF268
zinc finger protein 268
chr11_+_34642656 0.28 ENST00000257831.3
ENST00000450654.2
EHF
ets homologous factor
chr11_-_44972476 0.28 ENST00000527685.1
ENST00000308212.5
TP53I11
tumor protein p53 inducible protein 11
chr3_+_148847371 0.27 ENST00000296051.2
ENST00000460120.1
HPS3
Hermansky-Pudlak syndrome 3
chr5_-_42811986 0.27 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr7_-_86849025 0.27 ENST00000257637.3
TMEM243
transmembrane protein 243, mitochondrial
chr17_+_46918925 0.27 ENST00000502761.1
CALCOCO2
calcium binding and coiled-coil domain 2
chr8_-_141774467 0.27 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
PTK2
protein tyrosine kinase 2
chr16_-_31161380 0.27 ENST00000569305.1
ENST00000418068.2
ENST00000268281.4
PRSS36
protease, serine, 36
chr17_+_66244071 0.27 ENST00000580548.1
ENST00000580753.1
ENST00000392720.2
ENST00000359783.4
ENST00000584837.1
ENST00000579724.1
ENST00000584494.1
ENST00000580837.1
AMZ2
archaelysin family metallopeptidase 2
chr17_-_63822563 0.27 ENST00000317442.8
CEP112
centrosomal protein 112kDa
chr7_-_54826869 0.26 ENST00000450622.1
SEC61G
Sec61 gamma subunit
chr16_-_12062333 0.26 ENST00000597717.1
AC007216.2
Uncharacterized protein
chr14_-_105708942 0.26 ENST00000549655.1
BRF1
BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
chr9_-_99616642 0.26 ENST00000478850.1
ENST00000481138.1
ZNF782
zinc finger protein 782
chr3_-_88108192 0.26 ENST00000309534.6
CGGBP1
CGG triplet repeat binding protein 1
chr2_-_85581623 0.26 ENST00000449375.1
ENST00000409984.2
ENST00000457495.2
ENST00000263854.6
RETSAT
retinol saturase (all-trans-retinol 13,14-reductase)
chr3_+_159706537 0.26 ENST00000305579.2
ENST00000480787.1
ENST00000466512.1
IL12A
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
chr15_-_83474806 0.26 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
FSD2
fibronectin type III and SPRY domain containing 2
chr2_-_225434538 0.26 ENST00000409096.1
CUL3
cullin 3
chr8_-_74206673 0.26 ENST00000396465.1
RPL7
ribosomal protein L7
chr10_-_115423792 0.26 ENST00000369360.3
ENST00000360478.3
ENST00000359988.3
ENST00000369358.4
NRAP
nebulin-related anchoring protein
chr1_-_12908578 0.26 ENST00000317869.6
HNRNPCL1
heterogeneous nuclear ribonucleoprotein C-like 1
chr12_-_39837192 0.26 ENST00000361961.3
ENST00000395670.3
KIF21A
kinesin family member 21A
chr19_+_46531127 0.25 ENST00000601033.1
CTC-344H19.4
CTC-344H19.4
chr4_+_86749045 0.25 ENST00000514229.1
ARHGAP24
Rho GTPase activating protein 24
chr10_+_60094735 0.25 ENST00000373910.4
UBE2D1
ubiquitin-conjugating enzyme E2D 1
chr16_-_31100284 0.25 ENST00000280606.6
PRSS53
protease, serine, 53
chr14_+_56078695 0.25 ENST00000416613.1
KTN1
kinectin 1 (kinesin receptor)
chr8_+_22429205 0.25 ENST00000520207.1
SORBS3
sorbin and SH3 domain containing 3
chr2_+_145425534 0.25 ENST00000432608.1
ENST00000597655.1
ENST00000598659.1
ENST00000600679.1
ENST00000601277.1
ENST00000451027.1
ENST00000445791.1
ENST00000596540.1
ENST00000596230.1
ENST00000594471.1
ENST00000598248.1
ENST00000597469.1
ENST00000431734.1
ENST00000595686.1
TEX41
testis expressed 41 (non-protein coding)
chr17_-_15168624 0.25 ENST00000312280.3
ENST00000494511.1
ENST00000580584.1
PMP22
peripheral myelin protein 22
chr2_+_201677390 0.25 ENST00000447069.1
BZW1
basic leucine zipper and W2 domains 1
chr17_+_57297807 0.25 ENST00000284116.4
ENST00000581140.1
ENST00000581276.1
GDPD1
glycerophosphodiester phosphodiesterase domain containing 1
chr12_+_124069070 0.25 ENST00000262225.3
ENST00000438031.2
TMED2
transmembrane emp24 domain trafficking protein 2
chr6_+_35265586 0.24 ENST00000542066.1
ENST00000316637.5
DEF6
differentially expressed in FDCP 6 homolog (mouse)
chr13_+_53216565 0.24 ENST00000357495.2
HNRNPA1L2
heterogeneous nuclear ribonucleoprotein A1-like 2
chr17_+_75277492 0.24 ENST00000427177.1
ENST00000591198.1
SEPT9
septin 9
chr5_+_154135453 0.24 ENST00000517616.1
ENST00000518892.1
LARP1
La ribonucleoprotein domain family, member 1
chr11_+_34999328 0.24 ENST00000526309.1
PDHX
pyruvate dehydrogenase complex, component X
chr11_-_14521349 0.24 ENST00000534234.1
COPB1
coatomer protein complex, subunit beta 1
chr2_+_36923830 0.24 ENST00000379242.3
ENST00000389975.3
VIT
vitrin
chr11_-_44972390 0.24 ENST00000395648.3
ENST00000531928.2
TP53I11
tumor protein p53 inducible protein 11
chr2_+_179316163 0.24 ENST00000409117.3
DFNB59
deafness, autosomal recessive 59
chr5_-_34919094 0.23 ENST00000341754.4
RAD1
RAD1 homolog (S. pombe)
chr14_+_24702099 0.23 ENST00000420554.2
GMPR2
guanosine monophosphate reductase 2
chr19_-_20748614 0.23 ENST00000596797.1
ZNF737
zinc finger protein 737
chr2_+_37571845 0.23 ENST00000537448.1
QPCT
glutaminyl-peptide cyclotransferase
chr2_+_103378472 0.23 ENST00000412401.2
TMEM182
transmembrane protein 182
chr7_-_92463210 0.23 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr3_-_56950407 0.23 ENST00000496106.1
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr14_+_24702073 0.22 ENST00000399440.2
GMPR2
guanosine monophosphate reductase 2
chr1_-_115301235 0.22 ENST00000525878.1
CSDE1
cold shock domain containing E1, RNA-binding
chr10_+_52094298 0.22 ENST00000595931.1
AC069547.1
HCG1745369; PRO3073; Uncharacterized protein
chr9_+_131445928 0.22 ENST00000372692.4
SET
SET nuclear oncogene
chr5_+_139505520 0.22 ENST00000333305.3
IGIP
IgA-inducing protein
chr11_+_93479588 0.22 ENST00000526335.1
C11orf54
chromosome 11 open reading frame 54
chr16_+_524850 0.22 ENST00000450428.1
ENST00000452814.1
RAB11FIP3
RAB11 family interacting protein 3 (class II)
chr11_-_4719072 0.22 ENST00000396950.3
ENST00000532598.1
OR51E2
olfactory receptor, family 51, subfamily E, member 2
chr1_-_160492994 0.21 ENST00000368055.1
ENST00000368057.3
ENST00000368059.3
SLAMF6
SLAM family member 6
chr17_-_19648416 0.21 ENST00000426645.2
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr5_-_68339648 0.21 ENST00000479830.2
CTC-498J12.1
CTC-498J12.1
chr12_-_104532062 0.21 ENST00000240055.3
NFYB
nuclear transcription factor Y, beta
chr19_+_41620335 0.21 ENST00000331105.2
CYP2F1
cytochrome P450, family 2, subfamily F, polypeptide 1
chr12_+_58176525 0.21 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
TSFM
Ts translation elongation factor, mitochondrial
chr9_+_124048864 0.21 ENST00000545652.1
GSN
gelsolin
chr17_-_62493131 0.21 ENST00000539111.2
POLG2
polymerase (DNA directed), gamma 2, accessory subunit
chr12_-_7261772 0.20 ENST00000545280.1
ENST00000543933.1
ENST00000545337.1
ENST00000544702.1
ENST00000266542.4
C1RL
complement component 1, r subcomponent-like
chr3_-_69249863 0.20 ENST00000478263.1
ENST00000462512.1
FRMD4B
FERM domain containing 4B
chr17_-_15587602 0.20 ENST00000416464.2
ENST00000578237.1
ENST00000581200.1
TRIM16
tripartite motif containing 16
chr3_+_101504200 0.20 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr5_+_175298674 0.20 ENST00000514150.1
CPLX2
complexin 2
chr7_-_86849883 0.20 ENST00000433078.1
TMEM243
transmembrane protein 243, mitochondrial
chr4_-_175443943 0.20 ENST00000296522.6
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr8_+_145159846 0.20 ENST00000532522.1
ENST00000527572.1
ENST00000527058.1
MAF1
MAF1 homolog (S. cerevisiae)
chr14_+_24702127 0.20 ENST00000557854.1
ENST00000348719.7
ENST00000559104.1
ENST00000456667.3
GMPR2
guanosine monophosphate reductase 2
chr6_-_136610911 0.20 ENST00000530767.1
ENST00000527759.1
ENST00000527536.1
ENST00000529826.1
ENST00000531224.1
ENST00000353331.4
BCLAF1
BCL2-associated transcription factor 1
chr19_+_59055412 0.19 ENST00000593582.1
TRIM28
tripartite motif containing 28
chr16_-_3137080 0.19 ENST00000574387.1
ENST00000571404.1
RP11-473M20.9
RP11-473M20.9
chr2_-_105953912 0.19 ENST00000610036.1
RP11-332H14.2
RP11-332H14.2
chrX_+_49091920 0.19 ENST00000376227.3
CCDC22
coiled-coil domain containing 22
chr17_-_34329084 0.19 ENST00000354059.4
ENST00000536149.1
CCL15
CCL14
chemokine (C-C motif) ligand 15
chemokine (C-C motif) ligand 14
chr17_-_37844267 0.19 ENST00000579146.1
ENST00000378011.4
ENST00000429199.2
ENST00000300658.4
PGAP3
post-GPI attachment to proteins 3
chr3_+_156807663 0.19 ENST00000467995.1
ENST00000474477.1
ENST00000471719.1
LINC00881
long intergenic non-protein coding RNA 881
chr2_+_161993412 0.19 ENST00000259075.2
ENST00000432002.1
TANK
TRAF family member-associated NFKB activator
chr7_-_104909435 0.19 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr14_+_24701819 0.19 ENST00000560139.1
ENST00000559910.1
GMPR2
guanosine monophosphate reductase 2
chr16_+_57496299 0.18 ENST00000219252.5
POLR2C
polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
chr2_-_103353277 0.18 ENST00000258436.5
MFSD9
major facilitator superfamily domain containing 9
chr11_-_64856497 0.18 ENST00000524632.1
ENST00000530719.1
AP003068.6
transmembrane protein 262
chr12_+_133758115 0.18 ENST00000541009.2
ENST00000592241.1
ZNF268
zinc finger protein 268

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.2 0.7 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.2 0.5 GO:0002188 translation reinitiation(GO:0002188)
0.2 0.5 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.2 0.5 GO:0046356 acetyl-CoA catabolic process(GO:0046356)
0.2 0.5 GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1 0.4 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.1 0.6 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.7 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.7 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.2 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1 0.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.3 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.1 0.1 GO:0044268 angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.1 0.3 GO:0008218 bioluminescence(GO:0008218)
0.1 0.3 GO:1901073 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.1 0.5 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.1 0.6 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.2 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 1.7 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.1 0.2 GO:0051598 meiotic recombination checkpoint(GO:0051598)
0.1 0.3 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1 0.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.3 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.4 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.3 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.2 GO:1901536 negative regulation of DNA demethylation(GO:1901536)
0.0 0.3 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.3 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.2 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.2 GO:0034255 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.2 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.0 0.1 GO:0000921 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.0 0.3 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.3 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.2 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.3 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.0 1.1 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.2 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.5 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.2 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.3 GO:2000508 regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0 0.2 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.1 GO:1903936 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 0.2 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.3 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.2 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.3 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.7 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.1 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.3 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384) tRNA transcription(GO:0009304)
0.0 0.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.3 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.4 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.4 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.3 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.1 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.4 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.5 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:1904628 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697) negative regulation of monocyte differentiation(GO:0045656) response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.3 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.3 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.3 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.1 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.0 0.2 GO:0001787 natural killer cell proliferation(GO:0001787)
0.0 0.1 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.0 GO:2000196 positive regulation of female gonad development(GO:2000196) regulation of progesterone secretion(GO:2000870)
0.0 0.2 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.2 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.0 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.1 GO:0044211 CTP salvage(GO:0044211)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.2 1.1 GO:1902560 GMP reductase complex(GO:1902560)
0.1 1.7 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.2 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.1 0.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.3 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 0.6 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.4 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 0.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.3 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.1 0.4 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 1.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.7 GO:0030478 actin cap(GO:0030478)
0.0 0.3 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.3 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.2 GO:1990423 RZZ complex(GO:1990423)
0.0 0.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.3 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.5 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.6 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.9 GO:0000791 euchromatin(GO:0000791)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.4 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.2 0.5 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 0.5 GO:0004145 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.2 1.1 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.7 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.4 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.6 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.3 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.1 0.4 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.5 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 0.7 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.3 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.1 0.2 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.2 GO:0000994 RNA polymerase III core binding(GO:0000994)
0.1 0.3 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.1 0.4 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.2 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 0.3 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.2 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.0 0.2 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.3 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.5 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.0 0.2 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 1.0 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.3 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.4 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.5 GO:0008494 translation activator activity(GO:0008494)
0.0 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0070330 aromatase activity(GO:0070330)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.3 GO:0055103 ligase regulator activity(GO:0055103)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation