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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for NKX2-6

Z-value: 0.89

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Transcription factors associated with NKX2-6

Gene Symbol Gene ID Gene Info
NKX2-6
ENSG00000180053.6 NK2 homeobox 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-6hg19_v2_chr8_-_23563922_235641110.277.3e-01Click!

Activity profile of NKX2-6 motif

Sorted Z-values of NKX2-6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_113354341 0.97 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr4_+_17579110 0.79 ENST00000606142.1
LAP3
leucine aminopeptidase 3
chr4_+_89299885 0.67 ENST00000380265.5
ENST00000273960.3
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr11_-_104480019 0.63 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
RP11-886D15.1
chr8_-_145086922 0.56 ENST00000530478.1
PARP10
poly (ADP-ribose) polymerase family, member 10
chr4_-_129491686 0.42 ENST00000514265.1
RP11-184M15.1
RP11-184M15.1
chr13_-_30951282 0.40 ENST00000420219.1
LINC00426
long intergenic non-protein coding RNA 426
chr3_-_42003613 0.39 ENST00000414606.1
ULK4
unc-51 like kinase 4
chr9_-_4859260 0.34 ENST00000599351.1
AL158147.2
HCG2011465; Uncharacterized protein
chr19_+_50433476 0.31 ENST00000596658.1
ATF5
activating transcription factor 5
chr19_-_44174330 0.31 ENST00000340093.3
PLAUR
plasminogen activator, urokinase receptor
chr10_-_6019552 0.31 ENST00000379977.3
ENST00000397251.3
ENST00000397248.2
IL15RA
interleukin 15 receptor, alpha
chr5_+_34757309 0.29 ENST00000397449.1
RAI14
retinoic acid induced 14
chr18_+_68002675 0.29 ENST00000584919.1
RP11-41O4.1
Uncharacterized protein
chr5_-_43412418 0.28 ENST00000537013.1
ENST00000361115.4
CCL28
chemokine (C-C motif) ligand 28
chr19_-_44174305 0.27 ENST00000601723.1
ENST00000339082.3
PLAUR
plasminogen activator, urokinase receptor
chr11_+_65265141 0.26 ENST00000534336.1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr10_-_6019984 0.25 ENST00000525219.2
IL15RA
interleukin 15 receptor, alpha
chr7_+_142498725 0.24 ENST00000466254.1
TRBC2
T cell receptor beta constant 2
chr9_-_19065082 0.24 ENST00000415524.1
HAUS6
HAUS augmin-like complex, subunit 6
chr8_-_133637624 0.24 ENST00000522789.1
LRRC6
leucine rich repeat containing 6
chr11_-_62521614 0.23 ENST00000527994.1
ENST00000394807.3
ZBTB3
zinc finger and BTB domain containing 3
chr6_+_126102292 0.23 ENST00000368357.3
NCOA7
nuclear receptor coactivator 7
chr17_+_33914424 0.22 ENST00000590432.1
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr10_-_6019455 0.22 ENST00000530685.1
ENST00000397255.3
ENST00000379971.1
ENST00000528354.1
ENST00000397250.2
ENST00000429135.2
IL15RA
interleukin 15 receptor, alpha
chr17_+_33914276 0.21 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr9_+_127023704 0.21 ENST00000373596.1
ENST00000425237.1
NEK6
NIMA-related kinase 6
chr18_+_39535239 0.21 ENST00000585528.1
PIK3C3
phosphatidylinositol 3-kinase, catalytic subunit type 3
chr3_+_171561127 0.21 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr6_+_24775641 0.20 ENST00000378054.2
ENST00000476555.1
GMNN
geminin, DNA replication inhibitor
chr15_+_43425672 0.20 ENST00000260403.2
TMEM62
transmembrane protein 62
chr6_-_72129806 0.20 ENST00000413945.1
ENST00000602878.1
ENST00000436803.1
ENST00000421704.1
ENST00000441570.1
LINC00472
long intergenic non-protein coding RNA 472
chr17_+_33914460 0.19 ENST00000537622.2
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr15_-_41120896 0.19 ENST00000299174.5
ENST00000427255.2
PPP1R14D
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr20_-_36793663 0.19 ENST00000536701.1
ENST00000536724.1
TGM2
transglutaminase 2
chr2_+_70142232 0.19 ENST00000540449.1
MXD1
MAX dimerization protein 1
chr4_-_77996032 0.18 ENST00000505609.1
CCNI
cyclin I
chr14_+_23654525 0.18 ENST00000399910.1
ENST00000492621.1
C14orf164
chromosome 14 open reading frame 164
chr1_+_16767195 0.18 ENST00000504551.2
ENST00000457722.2
ENST00000406746.1
ENST00000443980.2
NECAP2
NECAP endocytosis associated 2
chr3_-_42003479 0.18 ENST00000420927.1
ULK4
unc-51 like kinase 4
chr4_-_14889791 0.18 ENST00000509654.1
ENST00000515031.1
ENST00000505089.2
LINC00504
long intergenic non-protein coding RNA 504
chr17_-_26903900 0.18 ENST00000395319.3
ENST00000581807.1
ENST00000584086.1
ENST00000395321.2
ALDOC
aldolase C, fructose-bisphosphate
chr2_+_87769459 0.17 ENST00000414030.1
ENST00000437561.1
LINC00152
long intergenic non-protein coding RNA 152
chr1_+_205225319 0.17 ENST00000329800.7
TMCC2
transmembrane and coiled-coil domain family 2
chr12_+_13061894 0.17 ENST00000540125.1
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr9_-_111882195 0.17 ENST00000374586.3
TMEM245
transmembrane protein 245
chr10_-_4720301 0.16 ENST00000449712.1
LINC00704
long intergenic non-protein coding RNA 704
chr17_+_25621102 0.16 ENST00000581440.1
ENST00000262394.2
ENST00000583742.1
ENST00000579733.1
ENST00000583193.1
ENST00000581185.1
ENST00000427287.2
ENST00000348811.2
WSB1
WD repeat and SOCS box containing 1
chr6_-_110012380 0.16 ENST00000424296.2
ENST00000341338.6
ENST00000368948.2
ENST00000285397.5
AK9
adenylate kinase 9
chr4_-_156875003 0.16 ENST00000433477.3
CTSO
cathepsin O
chr1_-_1763721 0.16 ENST00000437146.1
GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr17_+_57807062 0.16 ENST00000587259.1
VMP1
vacuole membrane protein 1
chr8_-_36636676 0.16 ENST00000524132.1
ENST00000519451.1
RP11-962G15.1
RP11-962G15.1
chr17_-_55911970 0.16 ENST00000581805.1
ENST00000580960.1
RP11-60A24.3
RP11-60A24.3
chr1_+_16767167 0.16 ENST00000337132.5
NECAP2
NECAP endocytosis associated 2
chr20_+_54967663 0.15 ENST00000452950.1
CSTF1
cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr8_-_62602327 0.15 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH
aspartate beta-hydroxylase
chr12_-_8088773 0.15 ENST00000544291.1
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr6_+_122793058 0.15 ENST00000392491.2
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr12_-_56236690 0.15 ENST00000322569.4
MMP19
matrix metallopeptidase 19
chr17_+_60501228 0.15 ENST00000311506.5
METTL2A
methyltransferase like 2A
chr7_+_133812052 0.15 ENST00000285928.2
LRGUK
leucine-rich repeats and guanylate kinase domain containing
chr19_-_49843539 0.14 ENST00000602554.1
ENST00000358234.4
CTC-301O7.4
CTC-301O7.4
chr22_+_22723969 0.14 ENST00000390295.2
IGLV7-46
immunoglobulin lambda variable 7-46 (gene/pseudogene)
chr17_+_41150290 0.14 ENST00000589037.1
ENST00000253788.5
RPL27
ribosomal protein L27
chr5_+_173763250 0.14 ENST00000515513.1
ENST00000507361.1
ENST00000510234.1
RP11-267A15.1
RP11-267A15.1
chr14_-_30766223 0.14 ENST00000549360.1
ENST00000508469.2
CTD-2251F13.1
CTD-2251F13.1
chr12_+_70219052 0.13 ENST00000552032.2
ENST00000547771.2
MYRFL
myelin regulatory factor-like
chr2_+_70142189 0.13 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr6_+_109169591 0.12 ENST00000368972.3
ENST00000392644.4
ARMC2
armadillo repeat containing 2
chr11_-_6640585 0.12 ENST00000533371.1
ENST00000528657.1
ENST00000436873.2
ENST00000299427.6
TPP1
tripeptidyl peptidase I
chr1_+_169337172 0.12 ENST00000367807.3
ENST00000367808.3
ENST00000329281.2
ENST00000420531.1
BLZF1
basic leucine zipper nuclear factor 1
chr10_-_91403625 0.11 ENST00000322191.6
ENST00000342512.3
ENST00000371774.2
PANK1
pantothenate kinase 1
chr3_+_132316081 0.11 ENST00000249887.2
ACKR4
atypical chemokine receptor 4
chr1_-_17231271 0.11 ENST00000606899.1
RP11-108M9.6
RP11-108M9.6
chr17_+_80517216 0.11 ENST00000531030.1
ENST00000526383.2
FOXK2
forkhead box K2
chr1_-_149785236 0.11 ENST00000331491.1
HIST2H3D
histone cluster 2, H3d
chr13_+_115000521 0.11 ENST00000252457.5
ENST00000375308.1
CDC16
cell division cycle 16
chr9_+_125281420 0.10 ENST00000340750.1
OR1J4
olfactory receptor, family 1, subfamily J, member 4
chr19_-_49552006 0.10 ENST00000391869.3
CGB1
chorionic gonadotropin, beta polypeptide 1
chr14_-_50778872 0.10 ENST00000555610.1
ENST00000261699.4
L2HGDH
L-2-hydroxyglutarate dehydrogenase
chr8_-_121457608 0.10 ENST00000306185.3
MRPL13
mitochondrial ribosomal protein L13
chr6_+_12007897 0.10 ENST00000437559.1
RP11-456H18.2
RP11-456H18.2
chr11_-_76381029 0.10 ENST00000407242.2
ENST00000421973.1
LRRC32
leucine rich repeat containing 32
chr17_+_41150479 0.10 ENST00000589913.1
RPL27
ribosomal protein L27
chr17_-_56606705 0.10 ENST00000317268.3
SEPT4
septin 4
chr8_+_42396712 0.10 ENST00000518574.1
ENST00000417410.2
ENST00000414154.2
SMIM19
small integral membrane protein 19
chr15_-_34394008 0.10 ENST00000527822.1
ENST00000528949.1
EMC7
ER membrane protein complex subunit 7
chr1_-_200638964 0.09 ENST00000367348.3
ENST00000447706.2
ENST00000331314.6
DDX59
DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
chr11_-_64527425 0.09 ENST00000377432.3
PYGM
phosphorylase, glycogen, muscle
chr3_+_140981456 0.09 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr5_-_111091948 0.09 ENST00000447165.2
NREP
neuronal regeneration related protein
chr20_-_1373726 0.08 ENST00000400137.4
FKBP1A
FK506 binding protein 1A, 12kDa
chr1_-_31902614 0.08 ENST00000596131.1
AC114494.1
HCG1787699; Uncharacterized protein
chr19_-_51611623 0.08 ENST00000421832.2
CTU1
cytosolic thiouridylase subunit 1
chr19_+_42746927 0.08 ENST00000378108.1
AC006486.1
AC006486.1
chr17_-_56606639 0.08 ENST00000579371.1
SEPT4
septin 4
chr3_+_32726774 0.08 ENST00000538368.1
CNOT10
CCR4-NOT transcription complex, subunit 10
chr13_+_44453969 0.08 ENST00000325686.6
LACC1
laccase (multicopper oxidoreductase) domain containing 1
chr8_+_20054878 0.08 ENST00000276390.2
ENST00000519667.1
ATP6V1B2
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
chr1_+_144989309 0.08 ENST00000596396.1
AL590452.1
Uncharacterized protein
chr5_-_133510456 0.08 ENST00000520417.1
SKP1
S-phase kinase-associated protein 1
chr15_-_55563072 0.08 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A
RAB27A, member RAS oncogene family
chr3_-_157824292 0.08 ENST00000483851.2
SHOX2
short stature homeobox 2
chr15_-_28344439 0.08 ENST00000431101.1
ENST00000445578.1
ENST00000353809.5
ENST00000382996.2
ENST00000354638.3
OCA2
oculocutaneous albinism II
chr19_+_50148087 0.07 ENST00000601038.1
ENST00000595242.1
SCAF1
SR-related CTD-associated factor 1
chr19_-_37663572 0.07 ENST00000588354.1
ENST00000292841.5
ENST00000355533.2
ENST00000356958.4
ZNF585A
zinc finger protein 585A
chr3_-_160167301 0.07 ENST00000494486.1
TRIM59
tripartite motif containing 59
chr22_+_31160239 0.07 ENST00000445781.1
ENST00000401475.1
OSBP2
oxysterol binding protein 2
chr17_-_56606664 0.07 ENST00000580844.1
SEPT4
septin 4
chr8_+_42396936 0.07 ENST00000416469.2
SMIM19
small integral membrane protein 19
chr11_-_111383064 0.07 ENST00000525791.1
ENST00000456861.2
ENST00000356018.2
BTG4
B-cell translocation gene 4
chr19_+_39903185 0.07 ENST00000409794.3
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr1_-_21377447 0.07 ENST00000374937.3
ENST00000264211.8
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr7_+_75511362 0.07 ENST00000428119.1
RHBDD2
rhomboid domain containing 2
chr9_+_96846740 0.07 ENST00000288976.3
PTPDC1
protein tyrosine phosphatase domain containing 1
chr9_-_70465758 0.06 ENST00000489273.1
CBWD5
COBW domain containing 5
chr14_+_52164820 0.06 ENST00000554167.1
FRMD6
FERM domain containing 6
chr12_-_44152551 0.06 ENST00000416848.2
ENST00000550784.1
ENST00000547156.1
ENST00000549868.1
ENST00000553166.1
ENST00000551923.1
ENST00000431332.3
ENST00000344862.5
PUS7L
pseudouridylate synthase 7 homolog (S. cerevisiae)-like
chr2_+_203776937 0.06 ENST00000402905.3
ENST00000414490.1
ENST00000431787.1
ENST00000444724.1
ENST00000414857.1
ENST00000430899.1
ENST00000445120.1
ENST00000441569.1
ENST00000432024.1
ENST00000443740.1
ENST00000414439.1
ENST00000428585.1
ENST00000545253.1
ENST00000545262.1
ENST00000447539.1
ENST00000456821.2
ENST00000434998.1
ENST00000320443.8
CARF
calcium responsive transcription factor
chr7_-_38389573 0.06 ENST00000390344.2
TRGV5
T cell receptor gamma variable 5
chr17_-_29624343 0.06 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr3_+_100428268 0.06 ENST00000240851.4
TFG
TRK-fused gene
chr3_+_113609472 0.06 ENST00000472026.1
ENST00000462838.1
GRAMD1C
GRAM domain containing 1C
chr9_+_134065519 0.06 ENST00000531600.1
NUP214
nucleoporin 214kDa
chr3_-_39196049 0.06 ENST00000514182.1
CSRNP1
cysteine-serine-rich nuclear protein 1
chr19_-_42746714 0.06 ENST00000222330.3
GSK3A
glycogen synthase kinase 3 alpha
chr2_+_12246664 0.05 ENST00000449986.1
AC096559.1
AC096559.1
chr15_+_84841242 0.05 ENST00000558195.1
RP11-182J1.16
ubiquitin-conjugating enzyme E2Q family member 2-like
chr21_-_31311818 0.05 ENST00000535441.1
ENST00000309434.7
ENST00000327783.4
ENST00000389124.2
ENST00000389125.3
ENST00000399913.1
GRIK1
glutamate receptor, ionotropic, kainate 1
chr11_+_94277017 0.05 ENST00000358752.2
FUT4
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chr17_+_38334501 0.05 ENST00000541245.1
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr17_+_58755184 0.05 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3
breast carcinoma amplified sequence 3
chr1_+_156338993 0.05 ENST00000368249.1
ENST00000368246.2
ENST00000537040.1
ENST00000400992.2
ENST00000255013.3
ENST00000451864.2
RHBG
Rh family, B glycoprotein (gene/pseudogene)
chr16_+_22178282 0.05 ENST00000330898.4
SDR42E2
short chain dehydrogenase/reductase family 42E, member 2
chr7_-_6865826 0.05 ENST00000538180.1
CCZ1B
CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
chr12_-_56236711 0.05 ENST00000409200.3
MMP19
matrix metallopeptidase 19
chr1_-_19578003 0.05 ENST00000375199.3
ENST00000375208.3
ENST00000356068.2
ENST00000477853.1
EMC1
ER membrane protein complex subunit 1
chr2_-_163099885 0.05 ENST00000443424.1
FAP
fibroblast activation protein, alpha
chr7_-_150777949 0.05 ENST00000482571.1
FASTK
Fas-activated serine/threonine kinase
chrX_+_139791917 0.05 ENST00000607004.1
ENST00000370535.3
LINC00632
long intergenic non-protein coding RNA 632
chr1_+_113010056 0.05 ENST00000369686.5
WNT2B
wingless-type MMTV integration site family, member 2B
chr8_-_121457332 0.05 ENST00000518918.1
MRPL13
mitochondrial ribosomal protein L13
chr20_-_36661826 0.05 ENST00000373448.2
ENST00000373447.3
TTI1
TELO2 interacting protein 1
chr11_-_64684672 0.04 ENST00000377264.3
ENST00000421419.2
ATG2A
autophagy related 2A
chr6_+_42584847 0.04 ENST00000372883.3
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr2_-_25565377 0.04 ENST00000264709.3
ENST00000406659.3
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr12_-_76377795 0.04 ENST00000552856.1
RP11-114H23.1
RP11-114H23.1
chr1_-_78444776 0.04 ENST00000370767.1
ENST00000421641.1
FUBP1
far upstream element (FUSE) binding protein 1
chr2_+_109335929 0.04 ENST00000283195.6
RANBP2
RAN binding protein 2
chr1_+_202431859 0.04 ENST00000391959.3
ENST00000367270.4
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr19_-_43835582 0.04 ENST00000595748.1
CTC-490G23.2
CTC-490G23.2
chr22_-_24096630 0.04 ENST00000248948.3
VPREB3
pre-B lymphocyte 3
chr11_+_118754475 0.04 ENST00000292174.4
CXCR5
chemokine (C-X-C motif) receptor 5
chr8_+_27629459 0.04 ENST00000523566.1
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr11_-_129817356 0.03 ENST00000526082.1
PRDM10
PR domain containing 10
chr22_+_23229960 0.03 ENST00000526893.1
ENST00000532223.2
ENST00000531372.1
IGLL5
immunoglobulin lambda-like polypeptide 5
chr7_-_112430647 0.03 ENST00000312814.6
TMEM168
transmembrane protein 168
chr19_-_14992264 0.03 ENST00000327462.2
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chr20_-_1373682 0.03 ENST00000381724.3
FKBP1A
FK506 binding protein 1A, 12kDa
chr1_-_36863481 0.03 ENST00000315732.2
LSM10
LSM10, U7 small nuclear RNA associated
chr2_-_182521823 0.03 ENST00000410087.3
ENST00000409440.3
CERKL
ceramide kinase-like
chr2_-_180871780 0.03 ENST00000410053.3
ENST00000295749.6
ENST00000404136.2
CWC22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr9_+_74729511 0.03 ENST00000545168.1
GDA
guanine deaminase
chr15_+_81475047 0.03 ENST00000559388.1
IL16
interleukin 16
chr17_+_49337881 0.03 ENST00000225298.7
UTP18
UTP18 small subunit (SSU) processome component homolog (yeast)
chr12_-_15103621 0.03 ENST00000536592.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr6_-_32977345 0.03 ENST00000450833.2
ENST00000374813.1
ENST00000229829.5
HLA-DOA
major histocompatibility complex, class II, DO alpha
chr17_-_34890759 0.03 ENST00000431794.3
MYO19
myosin XIX
chr3_-_81811312 0.03 ENST00000429644.2
GBE1
glucan (1,4-alpha-), branching enzyme 1
chr4_-_79860506 0.03 ENST00000295462.3
ENST00000380645.4
ENST00000512733.1
PAQR3
progestin and adipoQ receptor family member III
chr5_-_177210399 0.03 ENST00000510276.1
FAM153A
family with sequence similarity 153, member A
chr11_-_129817448 0.03 ENST00000304538.6
PRDM10
PR domain containing 10
chr10_-_105437909 0.03 ENST00000540321.1
SH3PXD2A
SH3 and PX domains 2A
chr8_-_17942432 0.03 ENST00000381733.4
ENST00000314146.10
ASAH1
N-acylsphingosine amidohydrolase (acid ceramidase) 1
chr17_-_39341594 0.03 ENST00000398472.1
KRTAP4-1
keratin associated protein 4-1
chr7_+_5938386 0.03 ENST00000537980.1
CCZ1
CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
chr12_-_50290839 0.03 ENST00000552863.1
FAIM2
Fas apoptotic inhibitory molecule 2
chr14_+_31494672 0.03 ENST00000542754.2
ENST00000313566.6
AP4S1
adaptor-related protein complex 4, sigma 1 subunit
chr19_-_40950182 0.03 ENST00000596456.1
SERTAD3
SERTA domain containing 3
chr12_-_50294033 0.03 ENST00000552669.1
FAIM2
Fas apoptotic inhibitory molecule 2
chrX_-_153637612 0.03 ENST00000369807.1
ENST00000369808.3
DNASE1L1
deoxyribonuclease I-like 1
chrX_-_47341928 0.03 ENST00000313116.7
ZNF41
zinc finger protein 41
chr5_+_147443534 0.03 ENST00000398454.1
ENST00000359874.3
ENST00000508733.1
ENST00000256084.7
SPINK5
serine peptidase inhibitor, Kazal type 5
chr17_-_34890732 0.03 ENST00000268852.9
MYO19
myosin XIX
chr16_+_69373323 0.03 ENST00000254940.5
NIP7
NIP7, nucleolar pre-rRNA processing protein
chr5_+_52083730 0.03 ENST00000282588.6
ENST00000274311.2
ITGA1
PELO
integrin, alpha 1
pelota homolog (Drosophila)
chr3_+_100428188 0.02 ENST00000418917.2
ENST00000490574.1
TFG
TRK-fused gene
chr5_-_9903938 0.02 ENST00000511616.1
CTD-2143L24.1
CTD-2143L24.1
chr5_+_175487692 0.02 ENST00000510151.1
FAM153B
family with sequence similarity 153, member B
chr9_-_125240235 0.02 ENST00000259357.2
OR1J1
olfactory receptor, family 1, subfamily J, member 1
chr22_-_50523760 0.02 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr1_+_159796534 0.02 ENST00000289707.5
SLAMF8
SLAM family member 8
chr7_+_5938351 0.02 ENST00000325974.6
CCZ1
CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
chr17_-_49337392 0.02 ENST00000376381.2
ENST00000586178.1
MBTD1
mbt domain containing 1
chr11_-_8816375 0.02 ENST00000530580.1
ST5
suppression of tumorigenicity 5
chr17_-_34890709 0.02 ENST00000544606.1
MYO19
myosin XIX
chr1_-_169337176 0.02 ENST00000472647.1
ENST00000367811.3
NME7
NME/NM23 family member 7
chr7_+_110731062 0.02 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chr19_+_7701985 0.02 ENST00000595950.1
ENST00000441779.2
ENST00000221283.5
ENST00000414284.2
STXBP2
syntaxin binding protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.1 0.6 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 0.6 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.3 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.2 GO:0061569 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.2 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.2 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.2 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.2 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 0.1 GO:0043474 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.2 GO:0001554 luteolysis(GO:0001554)
0.0 0.3 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.0 GO:0097325 melanocyte proliferation(GO:0097325)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0071879 UDP-glucose catabolic process(GO:0006258) positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.6 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.2 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.0 GO:0006147 guanine catabolic process(GO:0006147)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.0 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.0 0.0 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.6 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.0 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.0 0.6 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.1 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.0 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.0 0.2 GO:0097227 sperm annulus(GO:0097227)
0.0 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0030125 clathrin vesicle coat(GO:0030125)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.1 1.0 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.2 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.6 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.0 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.0 GO:0008892 guanine deaminase activity(GO:0008892)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane