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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for NKX3-2

Z-value: 0.93

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Transcription factors associated with NKX3-2

Gene Symbol Gene ID Gene Info
NKX3-2
ENSG00000109705.7 NK3 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX3-2hg19_v2_chr4_-_13546632_135466740.346.6e-01Click!

Activity profile of NKX3-2 motif

Sorted Z-values of NKX3-2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_42160486 0.48 ENST00000427054.1
AC104654.2
AC104654.2
chr12_-_113658892 0.35 ENST00000299732.2
ENST00000416617.2
IQCD
IQ motif containing D
chr19_+_54609230 0.35 ENST00000420296.1
NDUFA3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
chr12_-_54978086 0.33 ENST00000553113.1
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr12_+_34175398 0.32 ENST00000538927.1
ALG10
ALG10, alpha-1,2-glucosyltransferase
chrX_+_48660565 0.32 ENST00000413163.2
ENST00000441703.1
ENST00000426196.1
HDAC6
histone deacetylase 6
chr6_+_32821924 0.29 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr2_+_145780725 0.28 ENST00000451478.1
TEX41
testis expressed 41 (non-protein coding)
chrX_+_48660107 0.27 ENST00000376643.2
HDAC6
histone deacetylase 6
chr19_+_18544045 0.27 ENST00000599699.2
SSBP4
single stranded DNA binding protein 4
chr19_+_7694623 0.26 ENST00000594797.1
ENST00000456958.3
ENST00000601406.1
PET100
PET100 homolog (S. cerevisiae)
chr1_+_119957554 0.26 ENST00000543831.1
ENST00000433745.1
ENST00000369416.3
HSD3B2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr2_-_25451065 0.25 ENST00000606328.1
RP11-458N5.1
RP11-458N5.1
chr9_-_131940526 0.25 ENST00000372491.2
IER5L
immediate early response 5-like
chr22_+_38453207 0.22 ENST00000404072.3
ENST00000424694.1
PICK1
protein interacting with PRKCA 1
chr2_-_188312971 0.21 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
CALCRL
calcitonin receptor-like
chr11_+_59705928 0.21 ENST00000398992.1
OOSP1
oocyte secreted protein 1
chr3_+_48481658 0.20 ENST00000438607.2
TMA7
translation machinery associated 7 homolog (S. cerevisiae)
chrX_+_48660287 0.20 ENST00000444343.2
ENST00000376610.2
ENST00000334136.5
ENST00000376619.2
HDAC6
histone deacetylase 6
chr6_+_26156551 0.20 ENST00000304218.3
HIST1H1E
histone cluster 1, H1e
chr9_+_35906176 0.20 ENST00000354323.2
HRCT1
histidine rich carboxyl terminus 1
chr10_-_131762105 0.20 ENST00000368648.3
ENST00000355311.5
EBF3
early B-cell factor 3
chr3_-_146262293 0.20 ENST00000448205.1
PLSCR1
phospholipid scramblase 1
chr5_-_175965008 0.19 ENST00000537487.1
RNF44
ring finger protein 44
chr12_-_21928515 0.19 ENST00000537950.1
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr15_-_40401062 0.19 ENST00000354670.4
ENST00000559701.1
ENST00000557870.1
ENST00000558774.1
BMF
Bcl2 modifying factor
chr1_+_26606608 0.19 ENST00000319041.6
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr19_-_10444188 0.19 ENST00000293677.6
RAVER1
ribonucleoprotein, PTB-binding 1
chr9_-_95244781 0.18 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr6_+_80129989 0.18 ENST00000429444.1
RP1-232L24.3
RP1-232L24.3
chr8_+_67624653 0.18 ENST00000521198.2
SGK3
serum/glucocorticoid regulated kinase family, member 3
chr1_-_1590418 0.17 ENST00000341028.7
CDK11B
cyclin-dependent kinase 11B
chr12_+_4382917 0.17 ENST00000261254.3
CCND2
cyclin D2
chr19_-_5680231 0.17 ENST00000587950.1
C19orf70
chromosome 19 open reading frame 70
chr19_-_38747172 0.17 ENST00000347262.4
ENST00000591585.1
ENST00000301242.4
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr7_-_102119342 0.16 ENST00000393794.3
ENST00000292614.5
POLR2J
polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
chr6_+_37012607 0.16 ENST00000423336.1
COX6A1P2
cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2
chr11_+_76813886 0.16 ENST00000529803.1
OMP
olfactory marker protein
chr2_+_220379052 0.15 ENST00000347842.3
ENST00000358078.4
ASIC4
acid-sensing (proton-gated) ion channel family member 4
chr5_+_179220979 0.15 ENST00000292596.10
ENST00000401985.3
LTC4S
leukotriene C4 synthase
chr1_+_10509971 0.15 ENST00000320498.4
CORT
cortistatin
chr19_+_40477062 0.15 ENST00000455878.2
PSMC4
proteasome (prosome, macropain) 26S subunit, ATPase, 4
chr20_+_1115821 0.15 ENST00000435720.1
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr2_+_177015950 0.14 ENST00000306324.3
HOXD4
homeobox D4
chr22_-_21356375 0.14 ENST00000215742.4
ENST00000399133.2
THAP7
THAP domain containing 7
chr11_+_89867681 0.14 ENST00000534061.1
NAALAD2
N-acetylated alpha-linked acidic dipeptidase 2
chr22_+_38453378 0.14 ENST00000437453.1
ENST00000356976.3
PICK1
protein interacting with PRKCA 1
chr7_+_30174668 0.14 ENST00000415604.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr3_-_112218378 0.14 ENST00000334529.5
BTLA
B and T lymphocyte associated
chr9_+_134065506 0.14 ENST00000483497.2
NUP214
nucleoporin 214kDa
chr12_+_109569155 0.14 ENST00000539864.1
ACACB
acetyl-CoA carboxylase beta
chr20_+_2276639 0.13 ENST00000381458.5
TGM3
transglutaminase 3
chr22_-_31328881 0.13 ENST00000445980.1
MORC2
MORC family CW-type zinc finger 2
chr2_-_25016251 0.13 ENST00000328379.5
PTRHD1
peptidyl-tRNA hydrolase domain containing 1
chr7_+_73106926 0.13 ENST00000453316.1
WBSCR22
Williams Beuren syndrome chromosome region 22
chr2_+_25016282 0.13 ENST00000260662.1
CENPO
centromere protein O
chr14_-_67859422 0.13 ENST00000556532.1
PLEK2
pleckstrin 2
chr5_-_137514333 0.13 ENST00000411594.2
ENST00000430331.1
BRD8
bromodomain containing 8
chr6_+_42928485 0.13 ENST00000372808.3
GNMT
glycine N-methyltransferase
chr19_-_5680202 0.12 ENST00000590389.1
C19orf70
chromosome 19 open reading frame 70
chr3_+_169629354 0.12 ENST00000428432.2
ENST00000335556.3
SAMD7
sterile alpha motif domain containing 7
chr1_-_202858227 0.12 ENST00000367262.3
RABIF
RAB interacting factor
chr1_-_226065330 0.12 ENST00000436966.1
TMEM63A
transmembrane protein 63A
chr1_-_155145721 0.12 ENST00000295682.4
KRTCAP2
keratinocyte associated protein 2
chr2_-_38978492 0.12 ENST00000409276.1
ENST00000446327.2
ENST00000313117.6
SRSF7
serine/arginine-rich splicing factor 7
chr3_-_146262428 0.12 ENST00000486631.1
PLSCR1
phospholipid scramblase 1
chr1_+_156756667 0.12 ENST00000526188.1
ENST00000454659.1
PRCC
papillary renal cell carcinoma (translocation-associated)
chr18_-_3220106 0.12 ENST00000356443.4
ENST00000400569.3
MYOM1
myomesin 1
chr3_-_50541028 0.12 ENST00000266039.3
ENST00000435965.1
ENST00000395083.1
CACNA2D2
calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr11_+_64879317 0.12 ENST00000526809.1
ENST00000279263.7
ENST00000524986.1
ENST00000534371.1
ENST00000540748.1
ENST00000525385.1
ENST00000345348.5
ENST00000531321.1
ENST00000529414.1
ENST00000526085.1
ENST00000530750.1
TM7SF2
transmembrane 7 superfamily member 2
chr22_+_31489344 0.12 ENST00000404574.1
SMTN
smoothelin
chr8_-_37707356 0.12 ENST00000520601.1
ENST00000521170.1
ENST00000220659.6
BRF2
BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
chr7_+_110731062 0.12 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chrX_+_51928002 0.11 ENST00000375626.3
MAGED4
melanoma antigen family D, 4
chr19_+_36545833 0.11 ENST00000401500.2
ENST00000270301.7
ENST00000427823.2
WDR62
WD repeat domain 62
chr2_+_149402009 0.11 ENST00000457184.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr10_+_35415851 0.11 ENST00000374726.3
CREM
cAMP responsive element modulator
chr6_-_32821599 0.11 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr18_+_21464737 0.11 ENST00000586751.1
LAMA3
laminin, alpha 3
chrX_-_15332665 0.11 ENST00000537676.1
ENST00000344384.4
ASB11
ankyrin repeat and SOCS box containing 11
chr12_+_6309963 0.11 ENST00000382515.2
CD9
CD9 molecule
chr20_+_2821366 0.11 ENST00000453689.1
ENST00000417508.1
VPS16
vacuolar protein sorting 16 homolog (S. cerevisiae)
chr16_+_73420942 0.11 ENST00000554640.1
ENST00000562661.1
ENST00000561875.1
RP11-140I24.1
RP11-140I24.1
chr9_+_34458851 0.11 ENST00000545019.1
DNAI1
dynein, axonemal, intermediate chain 1
chr12_-_68845165 0.11 ENST00000360485.3
ENST00000441255.2
RP11-81H14.2
RP11-81H14.2
chr17_-_74137374 0.11 ENST00000322957.6
FOXJ1
forkhead box J1
chr17_+_7482785 0.11 ENST00000250092.6
ENST00000380498.6
ENST00000584502.1
CD68
CD68 molecule
chr3_-_116163830 0.11 ENST00000333617.4
LSAMP
limbic system-associated membrane protein
chr11_-_119993979 0.11 ENST00000524816.3
ENST00000525327.1
TRIM29
tripartite motif containing 29
chr19_+_48867652 0.11 ENST00000344846.2
SYNGR4
synaptogyrin 4
chr9_+_116263778 0.11 ENST00000394646.3
RGS3
regulator of G-protein signaling 3
chr17_-_7145475 0.11 ENST00000571129.1
ENST00000571253.1
ENST00000573928.1
GABARAP
GABA(A) receptor-associated protein
chr15_-_90777277 0.11 ENST00000328649.6
CIB1
calcium and integrin binding 1 (calmyrin)
chr19_+_39109735 0.11 ENST00000593149.1
ENST00000248342.4
ENST00000538434.1
ENST00000588934.1
ENST00000545173.2
ENST00000589307.1
ENST00000586513.1
ENST00000591409.1
ENST00000592558.1
EIF3K
eukaryotic translation initiation factor 3, subunit K
chr15_+_81475047 0.11 ENST00000559388.1
IL16
interleukin 16
chr2_+_62132781 0.11 ENST00000311832.5
COMMD1
copper metabolism (Murr1) domain containing 1
chr1_-_217262969 0.11 ENST00000361525.3
ESRRG
estrogen-related receptor gamma
chr1_-_156710916 0.11 ENST00000368211.4
MRPL24
mitochondrial ribosomal protein L24
chr16_-_28222797 0.11 ENST00000569951.1
ENST00000565698.1
XPO6
exportin 6
chr3_+_48507210 0.11 ENST00000433541.1
ENST00000422277.2
ENST00000436480.2
ENST00000444177.1
TREX1
three prime repair exonuclease 1
chr14_+_78227105 0.10 ENST00000439131.2
ENST00000355883.3
ENST00000557011.1
ENST00000556047.1
C14orf178
chromosome 14 open reading frame 178
chr12_-_120765565 0.10 ENST00000423423.3
ENST00000308366.4
PLA2G1B
phospholipase A2, group IB (pancreas)
chr1_+_162351503 0.10 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chr19_-_6720686 0.10 ENST00000245907.6
C3
complement component 3
chr8_-_49833978 0.10 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr8_+_86376081 0.10 ENST00000285379.5
CA2
carbonic anhydrase II
chr6_+_24357131 0.10 ENST00000274766.1
KAAG1
kidney associated antigen 1
chr9_-_80645520 0.10 ENST00000411677.1
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr14_-_24610779 0.10 ENST00000560403.1
ENST00000419198.2
ENST00000216799.4
EMC9
ER membrane protein complex subunit 9
chr20_+_2821340 0.10 ENST00000380445.3
ENST00000380469.3
VPS16
vacuolar protein sorting 16 homolog (S. cerevisiae)
chr11_-_26593649 0.10 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr19_-_18548921 0.10 ENST00000545187.1
ENST00000578352.1
ISYNA1
inositol-3-phosphate synthase 1
chr10_-_17171817 0.09 ENST00000377833.4
CUBN
cubilin (intrinsic factor-cobalamin receptor)
chr12_+_53693466 0.09 ENST00000267103.5
ENST00000548632.1
C12orf10
chromosome 12 open reading frame 10
chr4_-_168155700 0.09 ENST00000357545.4
ENST00000512648.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr17_+_30593195 0.09 ENST00000431505.2
ENST00000269051.4
ENST00000538145.1
RHBDL3
rhomboid, veinlet-like 3 (Drosophila)
chr11_+_66045634 0.09 ENST00000528852.1
ENST00000311445.6
CNIH2
cornichon family AMPA receptor auxiliary protein 2
chr10_-_46168156 0.09 ENST00000374371.2
ENST00000335258.7
ZFAND4
zinc finger, AN1-type domain 4
chr19_+_14672755 0.09 ENST00000594545.1
TECR
trans-2,3-enoyl-CoA reductase
chr3_-_100551141 0.09 ENST00000478235.1
ENST00000471901.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr2_-_208489707 0.09 ENST00000448007.2
ENST00000432416.1
ENST00000411432.1
METTL21A
methyltransferase like 21A
chr11_+_2421718 0.09 ENST00000380996.5
ENST00000333256.6
ENST00000380992.1
ENST00000437110.1
ENST00000435795.1
TSSC4
tumor suppressing subtransferable candidate 4
chr11_-_107590383 0.09 ENST00000525934.1
ENST00000531293.1
SLN
sarcolipin
chr7_-_8276508 0.09 ENST00000401396.1
ENST00000317367.5
ICA1
islet cell autoantigen 1, 69kDa
chr5_-_137514288 0.09 ENST00000454473.1
ENST00000418329.1
ENST00000455658.2
ENST00000230901.5
ENST00000402931.1
BRD8
bromodomain containing 8
chr1_-_78444738 0.09 ENST00000436586.2
ENST00000370768.2
FUBP1
far upstream element (FUSE) binding protein 1
chr7_-_22862406 0.09 ENST00000372879.4
TOMM7
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr2_+_74229812 0.09 ENST00000305799.7
TET3
tet methylcytosine dioxygenase 3
chr21_-_33985127 0.08 ENST00000290155.3
C21orf59
chromosome 21 open reading frame 59
chr6_-_27279949 0.08 ENST00000444565.1
ENST00000377451.2
POM121L2
POM121 transmembrane nucleoporin-like 2
chr4_-_168155730 0.08 ENST00000502330.1
ENST00000357154.3
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr9_+_34458771 0.08 ENST00000437363.1
ENST00000242317.4
DNAI1
dynein, axonemal, intermediate chain 1
chr12_-_113658826 0.08 ENST00000546692.1
IQCD
IQ motif containing D
chr2_-_85625857 0.08 ENST00000453973.1
CAPG
capping protein (actin filament), gelsolin-like
chr6_-_30080876 0.08 ENST00000376734.3
TRIM31
tripartite motif containing 31
chrX_-_49965663 0.08 ENST00000376056.2
ENST00000376058.2
ENST00000358526.2
AKAP4
A kinase (PRKA) anchor protein 4
chr2_-_70780770 0.08 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
TGFA
transforming growth factor, alpha
chr10_+_105005644 0.08 ENST00000441178.2
RP11-332O19.5
ribulose-5-phosphate-3-epimerase-like 1
chr8_-_29592736 0.08 ENST00000518623.1
LINC00589
long intergenic non-protein coding RNA 589
chr4_-_4228616 0.08 ENST00000296358.4
OTOP1
otopetrin 1
chr21_-_43816052 0.08 ENST00000398405.1
TMPRSS3
transmembrane protease, serine 3
chr17_-_42295870 0.08 ENST00000526094.1
ENST00000529383.1
ENST00000530828.1
UBTF
upstream binding transcription factor, RNA polymerase I
chr10_+_47746929 0.08 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2
AL603965.1
annexin A8-like 2
Protein LOC100996760
chr10_-_47173994 0.08 ENST00000414655.2
ENST00000545298.1
ENST00000359178.4
ENST00000358140.4
ENST00000503031.1
ANXA8L1
LINC00842
annexin A8-like 1
long intergenic non-protein coding RNA 842
chr21_+_33671160 0.08 ENST00000303645.5
MRAP
melanocortin 2 receptor accessory protein
chr3_+_177545563 0.08 ENST00000434309.1
RP11-91K9.1
RP11-91K9.1
chr11_+_35222629 0.08 ENST00000526553.1
CD44
CD44 molecule (Indian blood group)
chr6_-_32784687 0.08 ENST00000447394.1
ENST00000438763.2
HLA-DOB
major histocompatibility complex, class II, DO beta
chr20_+_53092232 0.08 ENST00000395939.1
DOK5
docking protein 5
chr2_-_27294500 0.08 ENST00000447619.1
ENST00000429985.1
ENST00000456793.1
OST4
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr11_-_128737163 0.08 ENST00000324003.3
ENST00000392665.2
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr14_+_64565442 0.08 ENST00000553308.1
SYNE2
spectrin repeat containing, nuclear envelope 2
chr12_+_57984943 0.08 ENST00000422156.3
PIP4K2C
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr7_+_90339169 0.08 ENST00000436577.2
CDK14
cyclin-dependent kinase 14
chrX_-_103087136 0.08 ENST00000243298.2
RAB9B
RAB9B, member RAS oncogene family
chr1_-_31769595 0.08 ENST00000263694.4
SNRNP40
small nuclear ribonucleoprotein 40kDa (U5)
chr15_+_75640068 0.07 ENST00000565051.1
ENST00000564257.1
ENST00000567005.1
NEIL1
nei endonuclease VIII-like 1 (E. coli)
chr19_-_17185848 0.07 ENST00000593360.1
HAUS8
HAUS augmin-like complex, subunit 8
chr12_-_62586543 0.07 ENST00000416284.3
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr11_+_67250490 0.07 ENST00000528641.2
ENST00000279146.3
AIP
aryl hydrocarbon receptor interacting protein
chr12_-_95397442 0.07 ENST00000547157.1
ENST00000547986.1
ENST00000327772.2
NDUFA12
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr20_+_53092123 0.07 ENST00000262593.5
DOK5
docking protein 5
chr1_+_149230680 0.07 ENST00000443018.1
RP11-403I13.5
RP11-403I13.5
chr12_-_57037284 0.07 ENST00000551570.1
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr8_-_16859690 0.07 ENST00000180166.5
FGF20
fibroblast growth factor 20
chr14_-_50778931 0.07 ENST00000555423.1
ENST00000421284.3
L2HGDH
L-2-hydroxyglutarate dehydrogenase
chr12_+_50794891 0.07 ENST00000517559.1
LARP4
La ribonucleoprotein domain family, member 4
chr18_-_13915530 0.07 ENST00000327606.3
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr8_-_49834299 0.07 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr7_+_129007964 0.07 ENST00000460109.1
ENST00000474594.1
ENST00000446212.1
AHCYL2
adenosylhomocysteinase-like 2
chr7_+_120629653 0.07 ENST00000450913.2
ENST00000340646.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr3_-_112218205 0.07 ENST00000383680.4
BTLA
B and T lymphocyte associated
chr3_+_111697843 0.07 ENST00000534857.1
ENST00000273359.3
ENST00000494817.1
ABHD10
abhydrolase domain containing 10
chr18_+_59000815 0.07 ENST00000262717.4
CDH20
cadherin 20, type 2
chr7_-_79082867 0.07 ENST00000419488.1
ENST00000354212.4
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr20_+_54987168 0.07 ENST00000360314.3
CASS4
Cas scaffolding protein family member 4
chr1_+_164528437 0.07 ENST00000485769.1
PBX1
pre-B-cell leukemia homeobox 1
chr12_+_57984965 0.07 ENST00000540759.2
ENST00000551772.1
ENST00000550465.1
ENST00000354947.5
PIP4K2C
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr14_+_23016437 0.07 ENST00000478163.3
TRAC
T cell receptor alpha constant
chr10_-_95360983 0.07 ENST00000371464.3
RBP4
retinol binding protein 4, plasma
chr10_-_75571341 0.07 ENST00000309979.6
NDST2
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr20_-_62493217 0.07 ENST00000601296.1
C20ORF135
C20ORF135
chr6_-_33663474 0.07 ENST00000594414.1
SBP1
SBP1; Uncharacterized protein
chr11_-_64511789 0.07 ENST00000419843.1
ENST00000394430.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr17_-_73150629 0.07 ENST00000356033.4
ENST00000405458.3
ENST00000409753.3
HN1
hematological and neurological expressed 1
chr5_-_115872142 0.07 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr17_-_46507537 0.07 ENST00000336915.6
SKAP1
src kinase associated phosphoprotein 1
chr16_-_20566616 0.07 ENST00000569163.1
ACSM2B
acyl-CoA synthetase medium-chain family member 2B
chr2_+_145780767 0.07 ENST00000599358.1
ENST00000596278.1
ENST00000596747.1
ENST00000608652.1
ENST00000609705.1
ENST00000608432.1
ENST00000596970.1
ENST00000602041.1
ENST00000601578.1
ENST00000596034.1
ENST00000414195.2
ENST00000594837.1
TEX41
testis expressed 41 (non-protein coding)
chr7_-_102213030 0.07 ENST00000511313.1
ENST00000513438.1
ENST00000513506.1
POLR2J3
polymerase (RNA) II (DNA directed) polypeptide J3
chr11_-_59436453 0.06 ENST00000300146.9
PATL1
protein associated with topoisomerase II homolog 1 (yeast)
chr19_+_843314 0.06 ENST00000544537.2
PRTN3
proteinase 3
chr10_-_75571566 0.06 ENST00000299641.4
NDST2
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr17_-_60883993 0.06 ENST00000583803.1
ENST00000456609.2
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr8_-_123706338 0.06 ENST00000521608.1
RP11-973F15.1
long intergenic non-protein coding RNA 1151
chr10_+_35416090 0.06 ENST00000354759.3
CREM
cAMP responsive element modulator
chr5_+_112074029 0.06 ENST00000512211.2
APC
adenomatous polyposis coli
chr5_-_59481406 0.06 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_-_48018680 0.06 ENST00000513178.1
CNGA1
cyclic nucleotide gated channel alpha 1
chr17_+_18855470 0.06 ENST00000395647.2
ENST00000395642.1
ENST00000417251.2
ENST00000395643.2
ENST00000395645.3
SLC5A10
solute carrier family 5 (sodium/sugar cotransporter), member 10

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX3-2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0070846 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.1 0.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.4 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.0 0.1 GO:0038163 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.3 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.0 0.1 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.0 0.1 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.1 GO:0044727 chromatin reprogramming in the zygote(GO:0044725) DNA demethylation of male pronucleus(GO:0044727)
0.0 0.1 GO:0046967 cytosol to ER transport(GO:0046967)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.0 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.0 0.2 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.1 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.1 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.1 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.2 GO:0030913 paranodal junction assembly(GO:0030913)
0.0 0.3 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.1 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.1 GO:0016333 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0 0.1 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.1 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.2 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.0 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.0 0.3 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.0 GO:2000690 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.1 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.0 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.2 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.1 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.3 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.1 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 1.2 GO:0016235 aggresome(GO:0016235)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.0 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:0005610 laminin-5 complex(GO:0005610)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 0.3 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 0.3 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.2 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.2 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.2 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0070996 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783) type 1 melanocortin receptor binding(GO:0070996)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0005333 acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0046979 TAP2 binding(GO:0046979)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.0 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.0 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation