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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for NR4A1

Z-value: 1.54

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Transcription factors associated with NR4A1

Gene Symbol Gene ID Gene Info
NR4A1
ENSG00000123358.15 nuclear receptor subfamily 4 group A member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR4A1hg19_v2_chr12_+_52450298_52450388-0.821.8e-01Click!

Activity profile of NR4A1 motif

Sorted Z-values of NR4A1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_126409159 2.02 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
C5orf63
chromosome 5 open reading frame 63
chr17_-_66287257 1.25 ENST00000327268.4
SLC16A6
solute carrier family 16, member 6
chr14_+_101295638 1.13 ENST00000523671.2
MEG3
maternally expressed 3 (non-protein coding)
chr5_-_141703713 1.00 ENST00000511815.1
SPRY4
sprouty homolog 4 (Drosophila)
chr14_-_101295407 0.96 ENST00000596284.1
AL117190.2
AL117190.2
chr10_-_128359074 0.95 ENST00000544758.1
C10orf90
chromosome 10 open reading frame 90
chr6_+_31895480 0.84 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2
CFB
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr6_+_31895467 0.83 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr14_-_77495007 0.83 ENST00000238647.3
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr5_+_73109339 0.69 ENST00000296799.4
ARHGEF28
Rho guanine nucleotide exchange factor (GEF) 28
chr3_-_117716418 0.68 ENST00000484092.1
RP11-384F7.2
RP11-384F7.2
chr19_+_4153598 0.68 ENST00000078445.2
ENST00000252587.3
ENST00000595923.1
ENST00000602257.1
ENST00000602147.1
CREB3L3
cAMP responsive element binding protein 3-like 3
chr14_-_104387888 0.66 ENST00000286953.3
C14orf2
chromosome 14 open reading frame 2
chr7_-_99774945 0.64 ENST00000292377.2
GPC2
glypican 2
chr2_-_25194476 0.61 ENST00000534855.1
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr17_+_9745786 0.59 ENST00000304773.5
GLP2R
glucagon-like peptide 2 receptor
chr17_-_66287310 0.58 ENST00000582867.1
SLC16A6
solute carrier family 16, member 6
chr17_-_38928414 0.55 ENST00000335552.4
KRT26
keratin 26
chr6_-_43595039 0.54 ENST00000307114.7
GTPBP2
GTP binding protein 2
chr8_+_145065521 0.53 ENST00000534791.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chrX_+_33744503 0.52 ENST00000439992.1
RP11-305F18.1
RP11-305F18.1
chr1_+_156589198 0.51 ENST00000456112.1
HAPLN2
hyaluronan and proteoglycan link protein 2
chr19_+_6372444 0.50 ENST00000245812.3
ALKBH7
alkB, alkylation repair homolog 7 (E. coli)
chr14_+_101295948 0.50 ENST00000452514.2
MEG3
maternally expressed 3 (non-protein coding)
chr10_-_17171817 0.50 ENST00000377833.4
CUBN
cubilin (intrinsic factor-cobalamin receptor)
chr17_+_41150290 0.49 ENST00000589037.1
ENST00000253788.5
RPL27
ribosomal protein L27
chr8_+_145065705 0.47 ENST00000533044.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr2_+_228678550 0.46 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr12_+_109577202 0.45 ENST00000377848.3
ENST00000377854.5
ACACB
acetyl-CoA carboxylase beta
chr13_-_33112956 0.45 ENST00000505213.1
N4BP2L2
NEDD4 binding protein 2-like 2
chr14_+_35591735 0.44 ENST00000604948.1
ENST00000605201.1
ENST00000250377.7
ENST00000321130.10
ENST00000534898.4
KIAA0391
KIAA0391
chr22_-_51017084 0.43 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr19_+_17416609 0.43 ENST00000602206.1
MRPL34
mitochondrial ribosomal protein L34
chr22_-_51016846 0.41 ENST00000312108.7
ENST00000395650.2
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr14_-_24711470 0.40 ENST00000559969.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr17_+_41150479 0.40 ENST00000589913.1
RPL27
ribosomal protein L27
chr12_+_54378849 0.40 ENST00000515593.1
HOXC10
homeobox C10
chr11_-_111649074 0.39 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr3_+_14989076 0.39 ENST00000413118.1
ENST00000425241.1
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr19_+_49713991 0.39 ENST00000597316.1
TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr15_-_41120896 0.37 ENST00000299174.5
ENST00000427255.2
PPP1R14D
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr6_+_31895254 0.34 ENST00000299367.5
ENST00000442278.2
C2
complement component 2
chr10_-_75351088 0.34 ENST00000451492.1
ENST00000413442.1
USP54
ubiquitin specific peptidase 54
chr19_+_17416457 0.33 ENST00000252602.1
MRPL34
mitochondrial ribosomal protein L34
chrX_-_48823165 0.32 ENST00000419374.1
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr2_+_234216454 0.32 ENST00000447536.1
ENST00000409110.1
SAG
S-antigen; retina and pineal gland (arrestin)
chr6_+_30594619 0.31 ENST00000318999.7
ENST00000376485.4
ENST00000376478.2
ENST00000319027.5
ENST00000376483.4
ENST00000329992.8
ENST00000330083.5
ATAT1
alpha tubulin acetyltransferase 1
chr1_-_161102421 0.30 ENST00000490843.2
ENST00000368006.3
ENST00000392188.1
ENST00000545495.1
DEDD
death effector domain containing
chr8_+_99439214 0.30 ENST00000287042.4
KCNS2
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2
chr4_-_89744365 0.30 ENST00000513837.1
ENST00000503556.1
FAM13A
family with sequence similarity 13, member A
chr5_+_127039075 0.30 ENST00000514853.2
CTC-228N24.1
CTC-228N24.1
chr10_-_103815874 0.29 ENST00000370033.4
ENST00000311122.5
C10orf76
chromosome 10 open reading frame 76
chr2_+_26568965 0.28 ENST00000260585.7
ENST00000447170.1
EPT1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr5_+_159895275 0.28 ENST00000517927.1
MIR146A
microRNA 146a
chr2_+_27282134 0.28 ENST00000441931.1
AGBL5
ATP/GTP binding protein-like 5
chr2_+_162016827 0.27 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TANK
TRAF family member-associated NFKB activator
chr13_-_33112899 0.27 ENST00000267068.3
ENST00000357505.6
ENST00000399396.3
N4BP2L2
NEDD4 binding protein 2-like 2
chr12_-_118490217 0.27 ENST00000542304.1
WSB2
WD repeat and SOCS box containing 2
chr4_-_89744314 0.27 ENST00000508369.1
FAM13A
family with sequence similarity 13, member A
chr14_-_35591433 0.26 ENST00000261475.5
ENST00000555644.1
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr12_-_94673956 0.25 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chrX_-_132095419 0.24 ENST00000370836.2
ENST00000521489.1
HS6ST2
heparan sulfate 6-O-sulfotransferase 2
chr1_-_33815486 0.24 ENST00000373418.3
PHC2
polyhomeotic homolog 2 (Drosophila)
chr20_+_31755934 0.23 ENST00000354932.5
BPIFA2
BPI fold containing family A, member 2
chr3_+_67048721 0.23 ENST00000295568.4
ENST00000484414.1
ENST00000460576.1
ENST00000417314.2
KBTBD8
kelch repeat and BTB (POZ) domain containing 8
chr7_+_99933730 0.23 ENST00000610247.1
PILRB
paired immunoglobin-like type 2 receptor beta
chr1_+_64059332 0.23 ENST00000540265.1
PGM1
phosphoglucomutase 1
chrX_-_108868390 0.22 ENST00000372101.2
KCNE1L
KCNE1-like
chr3_-_150966902 0.22 ENST00000424796.2
P2RY14
purinergic receptor P2Y, G-protein coupled, 14
chr4_-_159080806 0.22 ENST00000590648.1
FAM198B
family with sequence similarity 198, member B
chr18_+_43753974 0.22 ENST00000282059.6
ENST00000321319.6
C18orf25
chromosome 18 open reading frame 25
chr4_-_89744457 0.22 ENST00000395002.2
FAM13A
family with sequence similarity 13, member A
chr14_+_35591020 0.21 ENST00000603611.1
KIAA0391
KIAA0391
chr1_+_236849754 0.21 ENST00000542672.1
ENST00000366578.4
ACTN2
actinin, alpha 2
chr19_+_11546440 0.21 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
PRKCSH
protein kinase C substrate 80K-H
chr5_-_124084493 0.21 ENST00000509799.1
ZNF608
zinc finger protein 608
chr17_+_7123207 0.21 ENST00000584103.1
ENST00000579886.2
ACADVL
acyl-CoA dehydrogenase, very long chain
chr10_+_35484793 0.21 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr13_-_33112823 0.21 ENST00000504114.1
N4BP2L2
NEDD4 binding protein 2-like 2
chr1_+_104293028 0.20 ENST00000370079.3
AMY1C
amylase, alpha 1C (salivary)
chr4_-_40632140 0.20 ENST00000514782.1
RBM47
RNA binding motif protein 47
chr14_+_29236269 0.20 ENST00000313071.4
FOXG1
forkhead box G1
chr7_+_6048856 0.20 ENST00000223029.3
ENST00000400479.2
ENST00000395236.2
AIMP2
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr14_-_104387831 0.19 ENST00000557040.1
ENST00000414262.2
ENST00000555030.1
ENST00000554713.1
ENST00000553430.1
C14orf2
chromosome 14 open reading frame 2
chr4_+_159593271 0.18 ENST00000512251.1
ENST00000511912.1
ETFDH
electron-transferring-flavoprotein dehydrogenase
chr19_+_11546153 0.18 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
PRKCSH
protein kinase C substrate 80K-H
chr6_-_130536774 0.17 ENST00000532763.1
SAMD3
sterile alpha motif domain containing 3
chr1_+_14075903 0.17 ENST00000343137.4
ENST00000503842.1
ENST00000407521.3
ENST00000505823.1
PRDM2
PR domain containing 2, with ZNF domain
chr16_+_81272287 0.16 ENST00000425577.2
ENST00000564552.1
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr11_-_46638378 0.16 ENST00000529192.1
HARBI1
harbinger transposase derived 1
chr2_-_178257401 0.16 ENST00000464747.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr22_-_31364187 0.16 ENST00000215862.4
ENST00000397641.3
MORC2
MORC family CW-type zinc finger 2
chr2_+_162016804 0.16 ENST00000392749.2
ENST00000440506.1
TANK
TRAF family member-associated NFKB activator
chr6_+_53948328 0.15 ENST00000370876.2
MLIP
muscular LMNA-interacting protein
chr10_-_33625154 0.15 ENST00000265371.4
NRP1
neuropilin 1
chr11_+_86748957 0.15 ENST00000526733.1
ENST00000532959.1
TMEM135
transmembrane protein 135
chr12_-_95467267 0.15 ENST00000330677.7
NR2C1
nuclear receptor subfamily 2, group C, member 1
chr13_-_30880979 0.14 ENST00000414289.1
KATNAL1
katanin p60 subunit A-like 1
chr15_-_42783303 0.14 ENST00000565380.1
ENST00000564754.1
ZNF106
zinc finger protein 106
chr19_+_11546093 0.14 ENST00000591462.1
PRKCSH
protein kinase C substrate 80K-H
chr8_-_120685608 0.13 ENST00000427067.2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr10_+_26986582 0.12 ENST00000376215.5
ENST00000376203.5
PDSS1
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr16_+_9185450 0.12 ENST00000327827.7
C16orf72
chromosome 16 open reading frame 72
chr12_+_32654965 0.12 ENST00000472289.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr7_+_119913688 0.12 ENST00000331113.4
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr2_-_207024134 0.11 ENST00000457011.1
ENST00000440274.1
ENST00000432169.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr4_+_176986978 0.11 ENST00000508596.1
ENST00000393643.2
WDR17
WD repeat domain 17
chr3_-_113465065 0.11 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr20_-_42815733 0.10 ENST00000342272.3
JPH2
junctophilin 2
chr17_-_36499693 0.10 ENST00000342292.4
GPR179
G protein-coupled receptor 179
chr12_+_93963590 0.10 ENST00000340600.2
SOCS2
suppressor of cytokine signaling 2
chr17_-_7307358 0.10 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
TMEM256
TMEM256-PLSCR3
transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr2_+_207024306 0.09 ENST00000236957.5
ENST00000392221.1
ENST00000392222.2
ENST00000445505.1
EEF1B2
eukaryotic translation elongation factor 1 beta 2
chr12_-_16758873 0.09 ENST00000535535.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr14_+_35591509 0.09 ENST00000604073.1
KIAA0391
KIAA0391
chr8_-_92053042 0.09 ENST00000520014.1
TMEM55A
transmembrane protein 55A
chr5_-_142784888 0.09 ENST00000514699.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr12_-_16758835 0.09 ENST00000541295.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr11_+_278365 0.09 ENST00000534750.1
NLRP6
NLR family, pyrin domain containing 6
chr14_-_35591156 0.09 ENST00000554361.1
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr17_+_48423453 0.09 ENST00000017003.2
ENST00000509778.1
ENST00000507602.1
XYLT2
xylosyltransferase II
chr3_+_51741072 0.09 ENST00000395052.3
GRM2
glutamate receptor, metabotropic 2
chr7_-_81399678 0.09 ENST00000412881.1
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr1_-_161102367 0.08 ENST00000464113.1
DEDD
death effector domain containing
chr1_+_2398876 0.08 ENST00000449969.1
PLCH2
phospholipase C, eta 2
chr12_+_21679220 0.08 ENST00000256969.2
C12orf39
chromosome 12 open reading frame 39
chr12_+_32655110 0.08 ENST00000546442.1
ENST00000583694.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr7_-_6048702 0.08 ENST00000265849.7
PMS2
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
chr7_-_105517021 0.08 ENST00000318724.4
ENST00000419735.3
ATXN7L1
ataxin 7-like 1
chr7_+_120969045 0.07 ENST00000222462.2
WNT16
wingless-type MMTV integration site family, member 16
chr6_+_31895287 0.07 ENST00000447952.2
C2
complement component 2
chr7_-_81399438 0.07 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr10_-_69991865 0.07 ENST00000373673.3
ATOH7
atonal homolog 7 (Drosophila)
chr5_-_27038683 0.07 ENST00000511822.1
ENST00000231021.4
CDH9
cadherin 9, type 2 (T1-cadherin)
chr12_-_16759711 0.07 ENST00000447609.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr2_-_207024233 0.06 ENST00000423725.1
ENST00000233190.6
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr12_-_109219937 0.06 ENST00000546697.1
SSH1
slingshot protein phosphatase 1
chr17_-_2169425 0.06 ENST00000570606.1
ENST00000354901.4
SMG6
SMG6 nonsense mediated mRNA decay factor
chr20_-_42816206 0.06 ENST00000372980.3
JPH2
junctophilin 2
chr12_+_49687425 0.05 ENST00000257860.4
PRPH
peripherin
chr5_-_142784101 0.05 ENST00000503201.1
ENST00000502892.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr7_-_6048650 0.05 ENST00000382321.4
ENST00000406569.3
PMS2
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
chr7_-_81399287 0.05 ENST00000354224.6
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chrX_-_43741594 0.05 ENST00000536181.1
ENST00000378069.4
MAOB
monoamine oxidase B
chr7_-_107443652 0.05 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3
solute carrier family 26 (anion exchanger), member 3
chr2_+_162016916 0.05 ENST00000405852.1
TANK
TRAF family member-associated NFKB activator
chr3_+_138340049 0.04 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr3_-_138763734 0.04 ENST00000413199.1
ENST00000502927.2
PRR23C
proline rich 23C
chr9_+_1051481 0.04 ENST00000358146.2
ENST00000259622.6
DMRT2
doublesex and mab-3 related transcription factor 2
chr9_+_137987825 0.04 ENST00000545657.1
OLFM1
olfactomedin 1
chr14_-_95624227 0.04 ENST00000526495.1
DICER1
dicer 1, ribonuclease type III
chr6_+_44126545 0.04 ENST00000532171.1
ENST00000398776.1
ENST00000542245.1
CAPN11
calpain 11
chr12_-_118490403 0.04 ENST00000535496.1
WSB2
WD repeat and SOCS box containing 2
chr6_+_133561725 0.04 ENST00000452339.2
EYA4
eyes absent homolog 4 (Drosophila)
chr4_-_40632757 0.04 ENST00000511902.1
ENST00000505220.1
RBM47
RNA binding motif protein 47
chr7_+_12610338 0.03 ENST00000417018.1
SCIN
scinderin
chr11_+_120971882 0.03 ENST00000392793.1
TECTA
tectorin alpha
chr11_-_113577014 0.03 ENST00000544634.1
ENST00000539732.1
ENST00000538770.1
ENST00000536856.1
ENST00000544476.1
TMPRSS5
transmembrane protease, serine 5
chr1_+_174769006 0.02 ENST00000489615.1
RABGAP1L
RAB GTPase activating protein 1-like
chr6_-_152958521 0.02 ENST00000367255.5
ENST00000265368.4
ENST00000448038.1
ENST00000341594.5
SYNE1
spectrin repeat containing, nuclear envelope 1
chr14_-_35591679 0.02 ENST00000557278.1
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr12_+_50794891 0.02 ENST00000517559.1
LARP4
La ribonucleoprotein domain family, member 4
chr12_+_21525818 0.02 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
IAPP
islet amyloid polypeptide
chr4_-_74088800 0.02 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr14_+_32476072 0.02 ENST00000556949.1
RP11-187E13.2
Uncharacterized protein
chr19_-_16606988 0.01 ENST00000269881.3
CALR3
calreticulin 3
chr7_-_81399411 0.01 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr17_-_29624343 0.01 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr3_+_29322437 0.01 ENST00000434693.2
RBMS3
RNA binding motif, single stranded interacting protein 3
chr19_-_41256207 0.01 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
C19orf54
chromosome 19 open reading frame 54
chr12_+_32655048 0.00 ENST00000427716.2
ENST00000266482.3
FGD4
FYVE, RhoGEF and PH domain containing 4
chr14_-_95623607 0.00 ENST00000531162.1
ENST00000529720.1
ENST00000343455.3
DICER1
dicer 1, ribonuclease type III
chr10_-_75634326 0.00 ENST00000322635.3
ENST00000444854.2
ENST00000423381.1
ENST00000322680.3
ENST00000394762.2
CAMK2G
calcium/calmodulin-dependent protein kinase II gamma

Network of associatons between targets according to the STRING database.

First level regulatory network of NR4A1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0045362 interleukin-1 biosynthetic process(GO:0042222) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.9 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 0.4 GO:1990736 positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.1 1.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.5 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.1 0.5 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 0.5 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.1 0.5 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.8 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 0.2 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.1 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.7 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 0.2 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.4 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.1 0.4 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 0.5 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.7 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.4 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.2 GO:0061552 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.3 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.1 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.0 0.3 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0 1.0 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.7 GO:0002675 positive regulation of acute inflammatory response(GO:0002675)
0.0 0.2 GO:0046223 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.2 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.1 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.1 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.2 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.0 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.3 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.1 0.5 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.4 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.0 0.2 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.4 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.8 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 0.2 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.5 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.2 GO:0051373 FATZ binding(GO:0051373)
0.1 0.3 GO:0002046 opsin binding(GO:0002046)
0.1 0.2 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 1.7 GO:0001848 complement binding(GO:0001848)
0.0 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.7 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.2 GO:0015065 uridine nucleotide receptor activity(GO:0015065) UDP-activated nucleotide receptor activity(GO:0045029) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 1.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.1 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.9 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.0 GO:0004530 deoxyribonuclease I activity(GO:0004530)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 ST G ALPHA S PATHWAY G alpha s Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.6 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE