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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for PAX4

Z-value: 0.92

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Transcription factors associated with PAX4

Gene Symbol Gene ID Gene Info
PAX4
ENSG00000106331.10 paired box 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX4hg19_v2_chr7_-_127255724_127255780-0.861.4e-01Click!

Activity profile of PAX4 motif

Sorted Z-values of PAX4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_121477039 1.73 ENST00000257570.5
OASL
2'-5'-oligoadenylate synthetase-like
chr12_-_121476959 1.66 ENST00000339275.5
OASL
2'-5'-oligoadenylate synthetase-like
chr7_-_139763521 1.51 ENST00000263549.3
PARP12
poly (ADP-ribose) polymerase family, member 12
chr2_-_191878162 0.92 ENST00000540176.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr15_-_40401062 0.80 ENST00000354670.4
ENST00000559701.1
ENST00000557870.1
ENST00000558774.1
BMF
Bcl2 modifying factor
chr2_-_42160486 0.72 ENST00000427054.1
AC104654.2
AC104654.2
chr18_-_8337038 0.61 ENST00000594251.1
AP001094.1
Uncharacterized protein
chr5_-_126409159 0.52 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
C5orf63
chromosome 5 open reading frame 63
chr7_-_99756293 0.51 ENST00000316937.3
ENST00000456769.1
C7orf43
chromosome 7 open reading frame 43
chr14_+_78227105 0.50 ENST00000439131.2
ENST00000355883.3
ENST00000557011.1
ENST00000556047.1
C14orf178
chromosome 14 open reading frame 178
chr7_+_69064566 0.48 ENST00000403018.2
AUTS2
autism susceptibility candidate 2
chr6_+_31553978 0.47 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
LST1
leukocyte specific transcript 1
chr16_-_67224002 0.46 ENST00000563889.1
ENST00000564418.1
ENST00000545725.2
ENST00000314586.6
EXOC3L1
exocyst complex component 3-like 1
chr10_-_69991865 0.46 ENST00000373673.3
ATOH7
atonal homolog 7 (Drosophila)
chr2_+_202937972 0.43 ENST00000541917.1
ENST00000295844.3
AC079354.1
uncharacterized protein KIAA2012
chr7_-_108097144 0.42 ENST00000418239.1
NRCAM
neuronal cell adhesion molecule
chrX_-_52260355 0.42 ENST00000375602.1
ENST00000399800.3
XAGE1A
X antigen family, member 1A
chr2_+_232316906 0.42 ENST00000370380.2
AC017104.2
Uncharacterized protein
chr9_+_19049372 0.40 ENST00000380527.1
RRAGA
Ras-related GTP binding A
chr19_+_2977444 0.39 ENST00000246112.4
ENST00000453329.1
ENST00000482627.1
ENST00000452088.1
TLE6
transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
chrX_+_52511761 0.39 ENST00000399795.3
ENST00000375589.1
XAGE1C
X antigen family, member 1C
chr11_-_65314905 0.38 ENST00000527339.1
LTBP3
latent transforming growth factor beta binding protein 3
chr1_+_101702417 0.38 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chr5_+_150157444 0.37 ENST00000526627.1
SMIM3
small integral membrane protein 3
chrX_-_52533295 0.37 ENST00000375578.1
ENST00000396497.3
XAGE1D
X antigen family, member 1D
chrX_+_52238810 0.36 ENST00000437949.2
ENST00000375616.1
XAGE1B
X antigen family, member 1B
chr3_-_71632894 0.36 ENST00000493089.1
FOXP1
forkhead box P1
chr1_-_153585539 0.35 ENST00000368706.4
S100A16
S100 calcium binding protein A16
chr6_-_32806506 0.35 ENST00000374897.2
ENST00000452392.2
TAP2
TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Uncharacterized protein
chr12_-_109221160 0.35 ENST00000326470.5
SSH1
slingshot protein phosphatase 1
chr6_-_10694766 0.35 ENST00000460742.2
ENST00000259983.3
ENST00000379586.1
C6orf52
chromosome 6 open reading frame 52
chrX_-_52546189 0.33 ENST00000375570.1
ENST00000429372.2
XAGE1E
X antigen family, member 1E
chr11_+_114549108 0.33 ENST00000389586.4
ENST00000375475.5
NXPE2
neurexophilin and PC-esterase domain family, member 2
chr3_-_197476560 0.33 ENST00000273582.5
KIAA0226
KIAA0226
chr14_-_50053081 0.31 ENST00000396020.3
ENST00000245458.6
RPS29
ribosomal protein S29
chr8_+_145215928 0.31 ENST00000528919.1
MROH1
maestro heat-like repeat family member 1
chr7_+_133812052 0.31 ENST00000285928.2
LRGUK
leucine-rich repeats and guanylate kinase domain containing
chrX_-_47004878 0.31 ENST00000377811.3
NDUFB11
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
chr21_+_43933946 0.30 ENST00000352133.2
SLC37A1
solute carrier family 37 (glucose-6-phosphate transporter), member 1
chr9_+_134103496 0.30 ENST00000498010.1
ENST00000476004.1
ENST00000528406.1
NUP214
nucleoporin 214kDa
chr8_-_116681123 0.29 ENST00000519674.1
TRPS1
trichorhinophalangeal syndrome I
chr11_+_114168085 0.28 ENST00000541754.1
NNMT
nicotinamide N-methyltransferase
chr22_+_23229960 0.28 ENST00000526893.1
ENST00000532223.2
ENST00000531372.1
IGLL5
immunoglobulin lambda-like polypeptide 5
chr22_-_31688431 0.28 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr12_-_120763739 0.27 ENST00000549767.1
PLA2G1B
phospholipase A2, group IB (pancreas)
chr17_+_16284104 0.27 ENST00000577958.1
ENST00000302182.3
ENST00000577640.1
UBB
ubiquitin B
chr18_+_3448455 0.27 ENST00000549780.1
TGIF1
TGFB-induced factor homeobox 1
chr8_+_11666649 0.27 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr17_+_7184986 0.26 ENST00000317370.8
ENST00000571308.1
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chr5_+_143584814 0.26 ENST00000507359.3
KCTD16
potassium channel tetramerization domain containing 16
chr8_-_134309335 0.26 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
NDRG1
N-myc downstream regulated 1
chr6_-_32806483 0.25 ENST00000374899.4
TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr2_-_136875712 0.25 ENST00000241393.3
CXCR4
chemokine (C-X-C motif) receptor 4
chr7_+_80267973 0.24 ENST00000394788.3
ENST00000447544.2
CD36
CD36 molecule (thrombospondin receptor)
chr15_+_63340647 0.24 ENST00000404484.4
TPM1
tropomyosin 1 (alpha)
chr18_-_53255766 0.24 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr22_-_31688381 0.24 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr19_-_48016023 0.24 ENST00000598615.1
ENST00000597118.1
NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr19_-_36391434 0.23 ENST00000396901.1
ENST00000585925.1
NFKBID
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
chr6_+_133135580 0.23 ENST00000230050.3
RPS12
ribosomal protein S12
chr17_-_77005813 0.22 ENST00000590370.1
ENST00000591625.1
CANT1
calcium activated nucleotidase 1
chr15_+_63340553 0.22 ENST00000334895.5
TPM1
tropomyosin 1 (alpha)
chr19_-_51142540 0.22 ENST00000598997.1
SYT3
synaptotagmin III
chr16_+_14980632 0.22 ENST00000565655.1
NOMO1
NODAL modulator 1
chr17_+_7253667 0.22 ENST00000570504.1
ENST00000574499.1
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr19_+_9361606 0.22 ENST00000456448.1
OR7E24
olfactory receptor, family 7, subfamily E, member 24
chr15_-_60690932 0.21 ENST00000559818.1
ANXA2
annexin A2
chr2_-_217560248 0.21 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr1_-_153348067 0.21 ENST00000368737.3
S100A12
S100 calcium binding protein A12
chr11_-_59578202 0.21 ENST00000300151.4
MRPL16
mitochondrial ribosomal protein L16
chr4_+_14113592 0.21 ENST00000502759.1
ENST00000511200.1
ENST00000512754.1
ENST00000506739.1
LINC01085
long intergenic non-protein coding RNA 1085
chr2_+_201173667 0.20 ENST00000409755.3
SPATS2L
spermatogenesis associated, serine-rich 2-like
chrX_-_131623874 0.20 ENST00000436215.1
MBNL3
muscleblind-like splicing regulator 3
chr3_+_111805182 0.20 ENST00000430855.1
ENST00000431717.2
ENST00000264848.5
C3orf52
chromosome 3 open reading frame 52
chr11_+_1874200 0.20 ENST00000311604.3
LSP1
lymphocyte-specific protein 1
chrX_-_49121165 0.20 ENST00000376207.4
ENST00000376199.2
FOXP3
forkhead box P3
chrX_-_131623982 0.20 ENST00000370844.1
MBNL3
muscleblind-like splicing regulator 3
chr10_+_74653330 0.20 ENST00000334011.5
OIT3
oncoprotein induced transcript 3
chr12_-_66035968 0.20 ENST00000537250.1
RP11-230G5.2
RP11-230G5.2
chr7_+_72848092 0.19 ENST00000344575.3
FZD9
frizzled family receptor 9
chr21_+_26934165 0.19 ENST00000456917.1
MIR155HG
MIR155 host gene (non-protein coding)
chr17_-_77005860 0.19 ENST00000591773.1
ENST00000588611.1
ENST00000586916.2
ENST00000592033.1
ENST00000588075.1
ENST00000302345.2
ENST00000591811.1
CANT1
calcium activated nucleotidase 1
chr19_-_4457776 0.19 ENST00000301281.6
UBXN6
UBX domain protein 6
chr2_-_136873735 0.19 ENST00000409817.1
CXCR4
chemokine (C-X-C motif) receptor 4
chr2_-_217559517 0.19 ENST00000449583.1
IGFBP5
insulin-like growth factor binding protein 5
chr4_-_140544386 0.19 ENST00000561977.1
RP11-308D13.3
RP11-308D13.3
chr17_+_43299241 0.18 ENST00000328118.3
FMNL1
formin-like 1
chr1_-_155145721 0.18 ENST00000295682.4
KRTCAP2
keratinocyte associated protein 2
chr10_+_33271469 0.18 ENST00000414157.1
RP11-462L8.1
RP11-462L8.1
chr3_-_127872625 0.18 ENST00000464873.1
RUVBL1
RuvB-like AAA ATPase 1
chr2_+_12857043 0.18 ENST00000381465.2
TRIB2
tribbles pseudokinase 2
chr4_+_169575875 0.18 ENST00000503457.1
PALLD
palladin, cytoskeletal associated protein
chr19_-_49955050 0.18 ENST00000262265.5
PIH1D1
PIH1 domain containing 1
chr12_+_56546223 0.17 ENST00000550443.1
ENST00000207437.5
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr19_+_14544099 0.17 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
PKN1
protein kinase N1
chr1_+_41157361 0.16 ENST00000427410.2
ENST00000447388.3
ENST00000425457.2
ENST00000453631.1
ENST00000456393.2
NFYC
nuclear transcription factor Y, gamma
chr7_-_96339132 0.16 ENST00000413065.1
SHFM1
split hand/foot malformation (ectrodactyly) type 1
chr12_-_48164812 0.16 ENST00000549151.1
ENST00000548919.1
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr1_+_244816371 0.15 ENST00000263831.7
DESI2
desumoylating isopeptidase 2
chrX_+_47004599 0.15 ENST00000329236.7
RBM10
RNA binding motif protein 10
chr6_-_49755019 0.15 ENST00000304801.3
PGK2
phosphoglycerate kinase 2
chr4_+_47487285 0.15 ENST00000273859.3
ENST00000504445.1
ATP10D
ATPase, class V, type 10D
chr12_+_121570631 0.15 ENST00000546057.1
ENST00000377162.2
ENST00000328963.5
ENST00000535250.1
ENST00000541446.1
P2RX7
purinergic receptor P2X, ligand-gated ion channel, 7
chr7_+_26191809 0.15 ENST00000056233.3
NFE2L3
nuclear factor, erythroid 2-like 3
chr17_+_16284399 0.15 ENST00000535788.1
UBB
ubiquitin B
chr12_+_50017184 0.14 ENST00000548825.2
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr10_+_6186847 0.14 ENST00000536985.1
ENST00000379789.4
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr11_-_62368696 0.14 ENST00000527204.1
MTA2
metastasis associated 1 family, member 2
chr11_-_64545222 0.13 ENST00000433274.2
ENST00000432725.1
SF1
splicing factor 1
chr2_+_231860830 0.13 ENST00000424440.1
ENST00000452881.1
ENST00000433428.2
ENST00000455816.1
ENST00000440792.1
ENST00000423134.1
SPATA3
spermatogenesis associated 3
chr5_-_58882219 0.13 ENST00000505453.1
ENST00000360047.5
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_+_41157421 0.13 ENST00000372654.1
NFYC
nuclear transcription factor Y, gamma
chr19_-_49955096 0.13 ENST00000595550.1
PIH1D1
PIH1 domain containing 1
chr1_+_15480197 0.13 ENST00000400796.3
ENST00000434578.2
ENST00000376008.2
TMEM51
transmembrane protein 51
chr2_-_85839146 0.13 ENST00000306336.5
ENST00000409734.3
C2orf68
chromosome 2 open reading frame 68
chr4_-_85419603 0.13 ENST00000295886.4
NKX6-1
NK6 homeobox 1
chr19_-_51143075 0.13 ENST00000600079.1
ENST00000593901.1
SYT3
synaptotagmin III
chr17_-_77005801 0.12 ENST00000392446.5
CANT1
calcium activated nucleotidase 1
chr18_-_3874247 0.12 ENST00000581699.1
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr5_+_173473662 0.12 ENST00000519717.1
NSG2
Neuron-specific protein family member 2
chr1_-_201140673 0.12 ENST00000367333.2
TMEM9
transmembrane protein 9
chr10_+_102295616 0.12 ENST00000299163.6
HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chrM_+_5824 0.12 ENST00000361624.2
MT-CO1
mitochondrially encoded cytochrome c oxidase I
chrX_+_47004639 0.12 ENST00000345781.6
RBM10
RNA binding motif protein 10
chr1_-_25291475 0.12 ENST00000338888.3
ENST00000399916.1
RUNX3
runt-related transcription factor 3
chr11_-_62995986 0.12 ENST00000403374.2
SLC22A25
solute carrier family 22, member 25
chr6_+_31553901 0.12 ENST00000418507.2
ENST00000438075.2
ENST00000376100.3
ENST00000376111.4
LST1
leukocyte specific transcript 1
chr9_-_20622478 0.12 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr17_+_73089382 0.12 ENST00000538213.2
ENST00000584118.1
SLC16A5
solute carrier family 16 (monocarboxylate transporter), member 5
chr13_+_76334795 0.11 ENST00000526202.1
ENST00000465261.2
LMO7
LIM domain 7
chr4_+_75023816 0.11 ENST00000395759.2
ENST00000331145.6
ENST00000359107.5
ENST00000325278.6
MTHFD2L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
chr2_+_85839218 0.11 ENST00000448971.1
ENST00000442708.1
ENST00000450066.2
USP39
ubiquitin specific peptidase 39
chr6_-_25042231 0.11 ENST00000510784.2
FAM65B
family with sequence similarity 65, member B
chr14_+_76072096 0.11 ENST00000555058.1
FLVCR2
feline leukemia virus subgroup C cellular receptor family, member 2
chr1_-_151032040 0.11 ENST00000540998.1
ENST00000357235.5
CDC42SE1
CDC42 small effector 1
chrM_+_8527 0.11 ENST00000361899.2
MT-ATP6
mitochondrially encoded ATP synthase 6
chr11_-_35440796 0.10 ENST00000278379.3
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr2_+_203879568 0.10 ENST00000449802.1
NBEAL1
neurobeachin-like 1
chr19_-_10420459 0.10 ENST00000403352.1
ENST00000403903.3
ZGLP1
zinc finger, GATA-like protein 1
chr15_+_80445113 0.10 ENST00000407106.1
ENST00000261755.5
FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr18_-_53255379 0.10 ENST00000565908.2
TCF4
transcription factor 4
chr19_+_49622646 0.10 ENST00000334186.4
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr12_+_122181529 0.10 ENST00000541467.1
TMEM120B
transmembrane protein 120B
chr16_+_50730910 0.10 ENST00000300589.2
NOD2
nucleotide-binding oligomerization domain containing 2
chr12_-_118406028 0.10 ENST00000425217.1
KSR2
kinase suppressor of ras 2
chrX_+_110187513 0.10 ENST00000446737.1
ENST00000425146.1
PAK3
p21 protein (Cdc42/Rac)-activated kinase 3
chr4_+_174292058 0.09 ENST00000296504.3
SAP30
Sin3A-associated protein, 30kDa
chr8_+_104892639 0.09 ENST00000436393.2
RIMS2
regulating synaptic membrane exocytosis 2
chr17_+_72270380 0.09 ENST00000582036.1
ENST00000307504.5
DNAI2
dynein, axonemal, intermediate chain 2
chr4_+_30723003 0.09 ENST00000543491.1
PCDH7
protocadherin 7
chr7_-_96339167 0.09 ENST00000444799.1
ENST00000417009.1
ENST00000248566.2
SHFM1
split hand/foot malformation (ectrodactyly) type 1
chr22_-_39151463 0.09 ENST00000405510.1
ENST00000433561.1
SUN2
Sad1 and UNC84 domain containing 2
chr19_+_49891475 0.09 ENST00000447857.3
CCDC155
coiled-coil domain containing 155
chr8_+_21946681 0.09 ENST00000289921.7
FAM160B2
family with sequence similarity 160, member B2
chr17_-_41116454 0.09 ENST00000427569.2
ENST00000430739.1
AARSD1
alanyl-tRNA synthetase domain containing 1
chr8_-_145653885 0.09 ENST00000531032.1
ENST00000292510.4
ENST00000377348.2
ENST00000530790.1
ENST00000533806.1
VPS28
vacuolar protein sorting 28 homolog (S. cerevisiae)
chr11_-_31391276 0.09 ENST00000452803.1
DCDC1
doublecortin domain containing 1
chrX_-_131547596 0.09 ENST00000538204.1
ENST00000370849.3
MBNL3
muscleblind-like splicing regulator 3
chr19_+_13134772 0.09 ENST00000587760.1
ENST00000585575.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr18_-_32957260 0.09 ENST00000587422.1
ENST00000306346.1
ENST00000589332.1
ENST00000586687.1
ENST00000585522.1
ZNF396
zinc finger protein 396
chr12_+_56546363 0.09 ENST00000551834.1
ENST00000552568.1
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr12_+_31812121 0.09 ENST00000395763.3
METTL20
methyltransferase like 20
chr13_+_76334567 0.09 ENST00000321797.8
LMO7
LIM domain 7
chr1_-_72748417 0.08 ENST00000357731.5
NEGR1
neuronal growth regulator 1
chr5_-_159766528 0.08 ENST00000505287.2
CCNJL
cyclin J-like
chr1_-_202776392 0.08 ENST00000235790.4
KDM5B
lysine (K)-specific demethylase 5B
chr19_-_49622348 0.08 ENST00000408991.2
C19orf73
chromosome 19 open reading frame 73
chr9_-_123676827 0.08 ENST00000546084.1
TRAF1
TNF receptor-associated factor 1
chrX_+_65384052 0.08 ENST00000336279.5
ENST00000458621.1
HEPH
hephaestin
chr12_-_45269430 0.08 ENST00000395487.2
NELL2
NEL-like 2 (chicken)
chr8_+_22844995 0.08 ENST00000524077.1
RHOBTB2
Rho-related BTB domain containing 2
chr4_+_140586922 0.08 ENST00000265498.1
ENST00000506797.1
MGST2
microsomal glutathione S-transferase 2
chr18_+_29769978 0.08 ENST00000269202.6
ENST00000581447.1
MEP1B
meprin A, beta
chr6_+_152130240 0.08 ENST00000427531.2
ESR1
estrogen receptor 1
chr17_-_17480779 0.08 ENST00000395782.1
PEMT
phosphatidylethanolamine N-methyltransferase
chr8_+_143781513 0.08 ENST00000292430.6
ENST00000561179.1
ENST00000518841.1
ENST00000519387.1
LY6K
lymphocyte antigen 6 complex, locus K
chr5_+_119799927 0.08 ENST00000407149.2
ENST00000379551.2
PRR16
proline rich 16
chr15_+_80445232 0.07 ENST00000561421.1
FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chrX_-_131547625 0.07 ENST00000394311.2
MBNL3
muscleblind-like splicing regulator 3
chr18_-_60986613 0.07 ENST00000444484.1
BCL2
B-cell CLL/lymphoma 2
chr13_+_37247934 0.07 ENST00000315190.3
SERTM1
serine-rich and transmembrane domain containing 1
chr12_-_95044309 0.07 ENST00000261226.4
TMCC3
transmembrane and coiled-coil domain family 3
chr15_+_69373184 0.07 ENST00000558147.1
ENST00000440444.1
LINC00277
long intergenic non-protein coding RNA 277
chr10_-_14920599 0.07 ENST00000609399.1
RP11-398C13.6
RP11-398C13.6
chr5_-_13944652 0.07 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chr7_+_100482595 0.07 ENST00000448764.1
SRRT
serrate RNA effector molecule homolog (Arabidopsis)
chr12_-_16762971 0.07 ENST00000540590.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr18_-_3874271 0.07 ENST00000400149.3
ENST00000400155.1
ENST00000400150.3
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr11_+_22689648 0.07 ENST00000278187.3
GAS2
growth arrest-specific 2
chr6_+_31515337 0.07 ENST00000376148.4
ENST00000376145.4
NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr1_-_208084729 0.06 ENST00000310833.7
ENST00000356522.4
CD34
CD34 molecule
chr12_-_16762802 0.06 ENST00000534946.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr2_+_99797636 0.06 ENST00000409145.1
MRPL30
mitochondrial ribosomal protein L30
chr7_-_86595190 0.06 ENST00000398276.2
ENST00000416314.1
ENST00000425689.1
KIAA1324L
KIAA1324-like
chr5_-_20575959 0.06 ENST00000507958.1
CDH18
cadherin 18, type 2
chr17_-_42295870 0.06 ENST00000526094.1
ENST00000529383.1
ENST00000530828.1
UBTF
upstream binding transcription factor, RNA polymerase I
chr6_-_32083106 0.06 ENST00000442721.1
TNXB
tenascin XB
chr6_-_113754604 0.06 ENST00000421737.1
RP1-124C6.1
RP1-124C6.1
chr1_-_228594490 0.06 ENST00000366699.3
ENST00000284551.6
TRIM11
tripartite motif containing 11
chr17_+_45771420 0.06 ENST00000578982.1
TBKBP1
TBK1 binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.2 0.6 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.1 0.4 GO:1904204 skeletal muscle hypertrophy(GO:0014734) regulation of skeletal muscle hypertrophy(GO:1904204)
0.1 0.4 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.5 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.3 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.5 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.3 GO:1903939 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.1 0.3 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.2 GO:0002913 tolerance induction dependent upon immune response(GO:0002461) positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.1 0.4 GO:1902462 mesenchymal stem cell proliferation(GO:0097168) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.4 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.2 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.1 0.5 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.4 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 0.2 GO:0052362 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.1 0.3 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.4 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.1 GO:0043132 positive regulation of gamma-aminobutyric acid secretion(GO:0014054) NAD transport(GO:0043132)
0.0 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.4 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.2 GO:0030822 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.2 GO:1990523 bone regeneration(GO:1990523)
0.0 0.4 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.2 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.2 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.8 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 3.4 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.1 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.0 0.4 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.1 GO:0043375 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.5 GO:0021554 optic nerve development(GO:0021554)
0.0 0.2 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)
0.0 0.3 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0071657 macrophage colony-stimulating factor production(GO:0036301) granulocyte colony-stimulating factor production(GO:0071611) regulation of granulocyte colony-stimulating factor production(GO:0071655) positive regulation of granulocyte colony-stimulating factor production(GO:0071657) regulation of macrophage colony-stimulating factor production(GO:1901256) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
0.0 0.3 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.0 0.1 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:2000861 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721) estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.1 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.6 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0015747 urate transport(GO:0015747)
0.0 0.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.0 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.2 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.0 0.0 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.1 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0042825 TAP complex(GO:0042825)
0.1 0.4 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.3 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.5 GO:0097255 R2TP complex(GO:0097255)
0.0 0.2 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.8 GO:0032059 bleb(GO:0032059)
0.0 0.4 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.3 GO:0002177 manchette(GO:0002177)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.0 GO:0031251 PAN complex(GO:0031251)
0.0 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.5 GO:0000145 exocyst(GO:0000145)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 0.5 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.6 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 0.5 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 0.3 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.1 0.3 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.2 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.4 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.3 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 0.4 GO:0046625 sphingolipid binding(GO:0046625)
0.0 1.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.1 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.0 0.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.1 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.9 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.4 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.1 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.1 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.3 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.8 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 3.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)