Project

A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for PBX2

Z-value: 0.78

Motif logo

logo of

Transcription factors associated with PBX2

Gene Symbol Gene ID Gene Info
PBX2
ENSG00000204304.7 PBX homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PBX2hg19_v2_chr6_-_32157947_32157992-0.039.7e-01Click!

Activity profile of PBX2 motif

Sorted Z-values of PBX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_1128781 0.51 ENST00000293897.4
ENST00000562758.1
SSTR5
somatostatin receptor 5
chr14_-_55658323 0.47 ENST00000554067.1
ENST00000247191.2
DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr9_-_128246769 0.41 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr1_-_26231589 0.36 ENST00000374291.1
STMN1
stathmin 1
chrX_+_56590002 0.34 ENST00000338222.5
UBQLN2
ubiquilin 2
chr14_-_55658252 0.34 ENST00000395425.2
DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr12_-_28124903 0.33 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH
parathyroid hormone-like hormone
chr4_-_100065440 0.32 ENST00000508393.1
ENST00000265512.7
ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide
chr3_-_52864680 0.31 ENST00000406595.1
ENST00000485816.1
ENST00000434759.3
ENST00000346281.5
ENST00000266041.4
ITIH4
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr2_+_44396000 0.31 ENST00000409895.4
ENST00000409432.3
ENST00000282412.4
ENST00000378551.2
ENST00000345249.4
PPM1B
protein phosphatase, Mg2+/Mn2+ dependent, 1B
chr11_+_62432777 0.25 ENST00000532971.1
METTL12
methyltransferase like 12
chr17_+_7758374 0.24 ENST00000301599.6
ENST00000574668.1
TMEM88
transmembrane protein 88
chr1_+_62417957 0.24 ENST00000307297.7
ENST00000543708.1
INADL
InaD-like (Drosophila)
chr4_+_71019903 0.22 ENST00000344526.5
C4orf40
chromosome 4 open reading frame 40
chr11_-_111794446 0.21 ENST00000527950.1
CRYAB
crystallin, alpha B
chr7_+_134528635 0.21 ENST00000445569.2
CALD1
caldesmon 1
chr12_+_53835508 0.20 ENST00000551003.1
ENST00000549068.1
ENST00000549740.1
ENST00000546581.1
ENST00000549581.1
ENST00000541275.1
PRR13
PCBP2
proline rich 13
poly(rC) binding protein 2
chr14_-_54317532 0.19 ENST00000418927.1
AL162759.1
AL162759.1
chr2_+_20646824 0.19 ENST00000272233.4
RHOB
ras homolog family member B
chr7_-_32529973 0.19 ENST00000410044.1
ENST00000409987.1
ENST00000409782.1
ENST00000450169.2
LSM5
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chrX_+_119737806 0.17 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chr12_+_53835539 0.17 ENST00000547368.1
ENST00000379786.4
ENST00000551945.1
PRR13
proline rich 13
chr22_+_42017987 0.16 ENST00000405506.1
XRCC6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr2_-_99917639 0.15 ENST00000308528.4
LYG1
lysozyme G-like 1
chr5_-_39462390 0.14 ENST00000511792.1
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr14_+_58765305 0.13 ENST00000445108.1
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr11_+_68228186 0.12 ENST00000393799.2
ENST00000393800.2
ENST00000528635.1
ENST00000533127.1
ENST00000529907.1
ENST00000529344.1
ENST00000534534.1
ENST00000524845.1
ENST00000265637.4
ENST00000524904.1
ENST00000393801.3
ENST00000265636.5
ENST00000529710.1
PPP6R3
protein phosphatase 6, regulatory subunit 3
chr4_+_71017791 0.12 ENST00000502294.1
C4orf40
chromosome 4 open reading frame 40
chr1_+_101702417 0.11 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chr12_+_53835383 0.11 ENST00000429243.2
PRR13
proline rich 13
chr12_-_120189900 0.10 ENST00000546026.1
CIT
citron (rho-interacting, serine/threonine kinase 21)
chr12_-_39734783 0.09 ENST00000552961.1
KIF21A
kinesin family member 21A
chr4_-_100065419 0.08 ENST00000504125.1
ENST00000505590.1
ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide
chr10_-_45474237 0.08 ENST00000448778.1
ENST00000298295.3
C10orf10
chromosome 10 open reading frame 10
chr2_+_234602305 0.08 ENST00000406651.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr3_+_129159039 0.07 ENST00000507564.1
ENST00000431818.2
ENST00000504021.1
ENST00000349441.2
ENST00000348417.2
ENST00000440957.2
IFT122
intraflagellar transport 122 homolog (Chlamydomonas)
chr2_-_31440377 0.07 ENST00000444918.2
ENST00000403897.3
CAPN14
calpain 14
chr9_-_20382446 0.07 ENST00000380321.1
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr1_-_39339777 0.06 ENST00000397572.2
MYCBP
MYC binding protein
chr2_+_27255806 0.06 ENST00000238788.9
ENST00000404032.3
TMEM214
transmembrane protein 214
chr3_+_129158926 0.06 ENST00000347300.2
ENST00000296266.3
IFT122
intraflagellar transport 122 homolog (Chlamydomonas)
chr12_-_28125638 0.06 ENST00000545234.1
PTHLH
parathyroid hormone-like hormone
chr16_-_11492366 0.05 ENST00000595360.1
CTD-3088G3.8
Protein LOC388210
chr22_-_30642728 0.05 ENST00000403987.3
LIF
leukemia inhibitory factor
chr1_+_56880606 0.05 ENST00000451914.1
RP4-710M16.2
RP4-710M16.2
chr6_+_160211481 0.05 ENST00000367034.4
MRPL18
mitochondrial ribosomal protein L18
chr7_-_112727774 0.04 ENST00000297146.3
ENST00000501255.2
GPR85
G protein-coupled receptor 85
chr17_-_29151794 0.04 ENST00000324238.6
CRLF3
cytokine receptor-like factor 3
chr17_+_8191815 0.03 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RANGRF
RAN guanine nucleotide release factor
chr14_+_64854958 0.03 ENST00000555709.2
ENST00000554739.1
ENST00000554768.1
ENST00000216605.8
MTHFD1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
chr12_+_53835425 0.02 ENST00000549924.1
PRR13
proline rich 13
chr10_+_69869237 0.02 ENST00000373675.3
MYPN
myopalladin
chr10_+_47894572 0.02 ENST00000355876.5
FAM21B
family with sequence similarity 21, member B
chr14_+_58765103 0.01 ENST00000355431.3
ENST00000348476.3
ENST00000395168.3
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr10_+_124320156 0.01 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
DMBT1
deleted in malignant brain tumors 1
chr16_+_1832902 0.01 ENST00000262302.9
ENST00000563136.1
ENST00000565987.1
ENST00000543305.1
ENST00000568287.1
ENST00000565134.1
NUBP2
nucleotide binding protein 2
chr1_+_207038699 0.01 ENST00000367098.1
IL20
interleukin 20
chr2_-_190044480 0.01 ENST00000374866.3
COL5A2
collagen, type V, alpha 2

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 0.8 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.3 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.4 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.4 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.3 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.1 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.2 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.4 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.0 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.4 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0019115 benzaldehyde dehydrogenase activity(GO:0019115)
0.1 0.5 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.4 GO:0070300 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) phosphatidic acid binding(GO:0070300)
0.0 0.0 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation