ISMARA results: PBX2

Project

A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

Navigation

Downloads

Results for PBX2

Z-value: 0.78

Motif logo

Transcription factors associated with PBX2

Gene Symbol	Gene ID	Gene Info
PBX2 Ensembl NCBI GeneCards UniProt	ENSG00000204304.7	PBX homeobox 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
PBX2	hg19_v2_chr6_-_32157947_32157992	-0.03	9.7e-01	Click!

Activity profile of PBX2 motif

Sorted Z-values of PBX2 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr16_+_1128781 Show fit	0.51	ENST00000293897.4 ENST00000562758.1	SSTR5 Ensembl NCBI GeneCards UniProt Show fit	somatostatin receptor 5
chr14_-_55658323 Show fit	0.47	ENST00000554067.1 ENST00000247191.2	DLGAP5 Ensembl NCBI GeneCards UniProt Show fit	discs, large (Drosophila) homolog-associated protein 5
chr9_-_128246769 Show fit	0.41	ENST00000444226.1	MAPKAP1 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase associated protein 1
chr1_-_26231589 Show fit	0.36	ENST00000374291.1	STMN1 Ensembl NCBI GeneCards UniProt Show fit	stathmin 1
chrX_+_56590002 Show fit	0.34	ENST00000338222.5	UBQLN2 Ensembl NCBI GeneCards UniProt Show fit	ubiquilin 2
chr14_-_55658252 Show fit	0.34	ENST00000395425.2	DLGAP5 Ensembl NCBI GeneCards UniProt Show fit	discs, large (Drosophila) homolog-associated protein 5
chr12_-_28124903 Show fit	0.33	ENST00000395872.1 ENST00000354417.3 ENST00000201015.4	PTHLH Ensembl NCBI GeneCards UniProt Show fit	parathyroid hormone-like hormone
chr4_-_100065440 Show fit	0.32	ENST00000508393.1 ENST00000265512.7	ADH4 Ensembl NCBI GeneCards UniProt Show fit	alcohol dehydrogenase 4 (class II), pi polypeptide
chr3_-_52864680 Show fit	0.31	ENST00000406595.1 ENST00000485816.1 ENST00000434759.3 ENST00000346281.5 ENST00000266041.4	ITIH4 Ensembl NCBI GeneCards UniProt Show fit	inter-alpha-trypsin inhibitor heavy chain family, member 4
chr2_+_44396000 Show fit	0.31	ENST00000409895.4 ENST00000409432.3 ENST00000282412.4 ENST00000378551.2 ENST00000345249.4	PPM1B Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase, Mg2+/Mn2+ dependent, 1B

Showing 1 to 10 of 58 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX2

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	GO:0007079	mitotic chromosome movement towards spindle pole(GO:0007079)
0.1	0.5	GO:0038170	somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1	0.4	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1	0.4	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0	0.4	GO:0006069	ethanol oxidation(GO:0006069)
0.0	0.4	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.1	0.3	GO:1904020	regulation of G-protein coupled receptor internalization(GO:1904020)
0.0	0.3	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.1	0.2	GO:0002188	translation reinitiation(GO:0002188)
0.0	0.2	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)

Showing 1 to 10 of 18 entries

Gene overrepresentation in cellular_component category:

Search:

Show entries

Total log-likelihood	Term	Description
0.8	GO:0031616	spindle pole centrosome(GO:0031616)
0.4	GO:0031932	TORC2 complex(GO:0031932)
0.3	GO:0031089	platelet dense granule lumen(GO:0031089)
0.2	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.2	GO:0043564	Ku70:Ku80 complex(GO:0043564)
0.2	GO:0030478	actin cap(GO:0030478)
0.2	GO:0097512	cardiac myofibril(GO:0097512)
0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	GO:0030991	intraciliary transport particle A(GO:0030991)

Showing 1 to 9 of 9 entries

Gene overrepresentation in molecular_function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0004994	somatostatin receptor activity(GO:0004994)
0.1	0.4	GO:0019115	benzaldehyde dehydrogenase activity(GO:0019115)
0.0	0.4	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.4	GO:0070300	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) phosphatidic acid binding(GO:0070300)
0.0	0.2	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.0	0.2	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0	0.2	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.1	GO:0005146	leukemia inhibitory factor receptor binding(GO:0005146)
0.0	0.1	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.0	GO:0004487	methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)

Showing 1 to 10 of 10 entries

Gene overrepresentation in C2:CP:REACTOME category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.4	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation

Showing 1 to 1 of 1 entries

Results for PBX2

Z-value: 0.78

Motif logo

Transcription factors associated with PBX2

Activity-expression correlation:

Activity profile of PBX2 motif

Sorted Z-values of PBX2 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX2

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP:REACTOME category: