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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for PKNOX1_TGIF2

Z-value: 0.94

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Transcription factors associated with PKNOX1_TGIF2

Gene Symbol Gene ID Gene Info
PKNOX1
ENSG00000160199.10 PBX/knotted 1 homeobox 1
TGIF2
ENSG00000118707.5 TGFB induced factor homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PKNOX1hg19_v2_chr21_+_44394620_443947370.919.1e-02Click!
TGIF2hg19_v2_chr20_+_35202909_35203075-0.574.3e-01Click!

Activity profile of PKNOX1_TGIF2 motif

Sorted Z-values of PKNOX1_TGIF2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_63989004 1.05 ENST00000371088.4
EFCAB7
EF-hand calcium binding domain 7
chr12_+_62654155 0.84 ENST00000312635.6
ENST00000393654.3
ENST00000549237.1
USP15
ubiquitin specific peptidase 15
chr1_-_63988846 0.77 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
ITGB3BP
integrin beta 3 binding protein (beta3-endonexin)
chr18_-_52626622 0.67 ENST00000591504.1
CCDC68
coiled-coil domain containing 68
chr12_+_95611536 0.65 ENST00000549002.1
VEZT
vezatin, adherens junctions transmembrane protein
chr3_-_52719888 0.64 ENST00000458294.1
PBRM1
polybromo 1
chr9_+_111696664 0.64 ENST00000374624.3
ENST00000445175.1
FAM206A
family with sequence similarity 206, member A
chr7_+_76139741 0.63 ENST00000334348.3
ENST00000419923.2
ENST00000448265.3
ENST00000443097.2
UPK3B
uroplakin 3B
chr11_+_6411636 0.59 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr2_-_203103185 0.52 ENST00000409205.1
SUMO1
small ubiquitin-like modifier 1
chr4_-_175443788 0.51 ENST00000541923.1
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr6_+_26124373 0.51 ENST00000377791.2
ENST00000602637.1
HIST1H2AC
histone cluster 1, H2ac
chr18_-_54318353 0.50 ENST00000590954.1
ENST00000540155.1
TXNL1
thioredoxin-like 1
chr11_+_827553 0.48 ENST00000528542.2
ENST00000450448.1
EFCAB4A
EF-hand calcium binding domain 4A
chr2_+_191208601 0.47 ENST00000413239.1
ENST00000431594.1
ENST00000444194.1
INPP1
inositol polyphosphate-1-phosphatase
chr1_-_247171347 0.46 ENST00000339986.7
ENST00000487338.2
ZNF695
zinc finger protein 695
chr17_-_64225508 0.46 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr10_-_118764862 0.41 ENST00000260777.10
KIAA1598
KIAA1598
chr7_+_79765071 0.38 ENST00000457358.2
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr7_+_76139833 0.37 ENST00000257632.5
UPK3B
uroplakin 3B
chr9_-_123605177 0.37 ENST00000373904.5
ENST00000210313.3
PSMD5
proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
chr11_-_67415048 0.36 ENST00000529256.1
ACY3
aspartoacylase (aminocyclase) 3
chr3_-_3221358 0.36 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
CRBN
cereblon
chr15_-_37391614 0.36 ENST00000219869.9
MEIS2
Meis homeobox 2
chr3_-_142166904 0.35 ENST00000264951.4
XRN1
5'-3' exoribonuclease 1
chr17_+_68071389 0.35 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr8_-_8318847 0.35 ENST00000521218.1
CTA-398F10.2
CTA-398F10.2
chr6_-_160209471 0.34 ENST00000539948.1
TCP1
t-complex 1
chr1_+_246729815 0.34 ENST00000366511.1
CNST
consortin, connexin sorting protein
chr6_+_111195973 0.33 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
AMD1
adenosylmethionine decarboxylase 1
chr8_-_99837856 0.32 ENST00000518165.1
ENST00000419617.2
STK3
serine/threonine kinase 3
chr4_+_128886584 0.32 ENST00000513371.1
C4orf29
chromosome 4 open reading frame 29
chr8_+_72755367 0.32 ENST00000537896.1
RP11-383H13.1
Protein LOC100132891; cDNA FLJ53548
chr9_-_132805430 0.32 ENST00000446176.2
ENST00000355681.3
ENST00000420781.1
FNBP1
formin binding protein 1
chr15_-_76352069 0.32 ENST00000305435.10
ENST00000563910.1
NRG4
neuregulin 4
chr9_-_33447584 0.32 ENST00000297991.4
AQP3
aquaporin 3 (Gill blood group)
chr5_+_173763250 0.31 ENST00000515513.1
ENST00000507361.1
ENST00000510234.1
RP11-267A15.1
RP11-267A15.1
chr16_+_2588012 0.31 ENST00000354836.5
ENST00000389224.3
PDPK1
3-phosphoinositide dependent protein kinase-1
chr1_+_24286287 0.30 ENST00000334351.7
ENST00000374468.1
PNRC2
proline-rich nuclear receptor coactivator 2
chr4_+_166300084 0.29 ENST00000402744.4
CPE
carboxypeptidase E
chr5_-_55008072 0.29 ENST00000512208.1
SLC38A9
solute carrier family 38, member 9
chr21_+_35553045 0.28 ENST00000416145.1
ENST00000430922.1
ENST00000419881.2
LINC00310
long intergenic non-protein coding RNA 310
chr1_+_104104379 0.28 ENST00000435302.1
AMY2B
amylase, alpha 2B (pancreatic)
chr1_-_54872059 0.28 ENST00000371320.3
SSBP3
single stranded DNA binding protein 3
chr2_-_61765732 0.28 ENST00000443240.1
ENST00000436018.1
XPO1
exportin 1 (CRM1 homolog, yeast)
chr12_+_69201923 0.28 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr17_+_78518617 0.27 ENST00000537330.1
ENST00000570891.1
RPTOR
regulatory associated protein of MTOR, complex 1
chr3_-_52719912 0.27 ENST00000420148.1
PBRM1
polybromo 1
chr7_-_156685841 0.27 ENST00000354505.4
ENST00000540390.1
LMBR1
limb development membrane protein 1
chr11_+_6411670 0.27 ENST00000530395.1
ENST00000527275.1
SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr2_+_118846008 0.27 ENST00000245787.4
INSIG2
insulin induced gene 2
chr15_+_96904487 0.26 ENST00000600790.1
AC087477.1
Uncharacterized protein
chr15_-_37392086 0.25 ENST00000561208.1
MEIS2
Meis homeobox 2
chr3_-_142166796 0.25 ENST00000392981.2
XRN1
5'-3' exoribonuclease 1
chr15_+_49913175 0.25 ENST00000403028.3
DTWD1
DTW domain containing 1
chr8_+_97657449 0.25 ENST00000220763.5
CPQ
carboxypeptidase Q
chr15_+_43477455 0.25 ENST00000300213.4
CCNDBP1
cyclin D-type binding-protein 1
chr11_+_60552797 0.24 ENST00000308287.1
MS4A10
membrane-spanning 4-domains, subfamily A, member 10
chr5_+_43603229 0.24 ENST00000344920.4
ENST00000512996.2
NNT
nicotinamide nucleotide transhydrogenase
chr2_-_61765315 0.24 ENST00000406957.1
ENST00000401558.2
XPO1
exportin 1 (CRM1 homolog, yeast)
chr7_-_104909435 0.23 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr16_+_2587998 0.23 ENST00000441549.3
ENST00000268673.7
PDPK1
3-phosphoinositide dependent protein kinase-1
chr14_-_94856987 0.23 ENST00000449399.3
ENST00000404814.4
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr17_-_70053866 0.22 ENST00000540802.1
RP11-84E24.2
RP11-84E24.2
chr11_+_120207787 0.22 ENST00000397843.2
ENST00000356641.3
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr18_-_54305658 0.22 ENST00000586262.1
ENST00000217515.6
TXNL1
thioredoxin-like 1
chr14_+_103566481 0.22 ENST00000380069.3
EXOC3L4
exocyst complex component 3-like 4
chr7_-_156803329 0.21 ENST00000252971.6
MNX1
motor neuron and pancreas homeobox 1
chr4_-_114682224 0.21 ENST00000342666.5
ENST00000515496.1
ENST00000514328.1
ENST00000508738.1
ENST00000379773.2
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr3_-_33481835 0.21 ENST00000283629.3
UBP1
upstream binding protein 1 (LBP-1a)
chr9_-_123639445 0.21 ENST00000312189.6
PHF19
PHD finger protein 19
chr15_+_49913201 0.21 ENST00000329873.5
ENST00000558653.1
ENST00000559164.1
ENST00000560632.1
ENST00000559405.1
ENST00000251250.6
DTWD1
DTW domain containing 1
chr10_-_11574274 0.21 ENST00000277575.5
USP6NL
USP6 N-terminal like
chr6_-_131949200 0.21 ENST00000539158.1
ENST00000368058.1
MED23
mediator complex subunit 23
chr1_+_154966058 0.21 ENST00000392487.1
LENEP
lens epithelial protein
chr14_-_94857004 0.21 ENST00000557492.1
ENST00000448921.1
ENST00000437397.1
ENST00000355814.4
ENST00000393088.4
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr19_-_12512062 0.21 ENST00000595766.1
ENST00000430385.3
ZNF799
zinc finger protein 799
chr12_+_10658489 0.21 ENST00000538173.1
EIF2S3L
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chrX_+_16804544 0.20 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr1_+_186649754 0.20 ENST00000608917.1
RP5-973M2.2
RP5-973M2.2
chr5_-_154230130 0.20 ENST00000519501.1
ENST00000518651.1
ENST00000517938.1
ENST00000520461.1
FAXDC2
fatty acid hydroxylase domain containing 2
chr10_+_28822636 0.20 ENST00000442148.1
ENST00000448193.1
WAC
WW domain containing adaptor with coiled-coil
chr8_+_97506033 0.20 ENST00000518385.1
SDC2
syndecan 2
chr3_-_52488048 0.20 ENST00000232975.3
TNNC1
troponin C type 1 (slow)
chr10_+_49514698 0.20 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
MAPK8
mitogen-activated protein kinase 8
chr2_+_191208196 0.19 ENST00000392329.2
ENST00000322522.4
ENST00000430311.1
ENST00000541441.1
INPP1
inositol polyphosphate-1-phosphatase
chr10_-_124768300 0.19 ENST00000368886.5
IKZF5
IKAROS family zinc finger 5 (Pegasus)
chr3_-_169587621 0.19 ENST00000523069.1
ENST00000316428.5
ENST00000264676.5
LRRC31
leucine rich repeat containing 31
chr8_-_17752912 0.19 ENST00000398054.1
ENST00000381840.2
FGL1
fibrinogen-like 1
chr2_+_233925064 0.19 ENST00000359570.5
ENST00000538935.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr4_+_57774042 0.18 ENST00000309042.7
REST
RE1-silencing transcription factor
chr2_-_74780176 0.18 ENST00000409549.1
LOXL3
lysyl oxidase-like 3
chr9_-_100459639 0.18 ENST00000375128.4
XPA
xeroderma pigmentosum, complementation group A
chr6_-_131949305 0.17 ENST00000368053.4
ENST00000354577.4
ENST00000403834.3
ENST00000540546.1
ENST00000368068.3
ENST00000368060.3
MED23
mediator complex subunit 23
chr5_-_81046904 0.17 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chr12_-_31882027 0.17 ENST00000541931.1
ENST00000535408.1
AMN1
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr10_-_118765081 0.17 ENST00000392903.2
ENST00000355371.4
KIAA1598
KIAA1598
chr12_-_31881944 0.17 ENST00000537562.1
ENST00000537960.1
ENST00000536761.1
ENST00000542781.1
ENST00000457428.2
AMN1
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr9_-_6470375 0.17 ENST00000355513.4
C9orf38
chromosome 9 open reading frame 38
chr17_+_68071458 0.17 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr21_-_34144157 0.17 ENST00000331923.4
PAXBP1
PAX3 and PAX7 binding protein 1
chr15_+_36871983 0.17 ENST00000437989.2
ENST00000569302.1
C15orf41
chromosome 15 open reading frame 41
chr1_+_203765437 0.17 ENST00000550078.1
ZBED6
zinc finger, BED-type containing 6
chr5_-_74348371 0.17 ENST00000503568.1
RP11-229C3.2
RP11-229C3.2
chr12_+_11081828 0.17 ENST00000381847.3
ENST00000396400.3
PRH2
proline-rich protein HaeIII subfamily 2
chr2_+_217082311 0.17 ENST00000597904.1
RP11-566E18.3
RP11-566E18.3
chr17_-_29151686 0.17 ENST00000544695.1
CRLF3
cytokine receptor-like factor 3
chr12_-_104531785 0.17 ENST00000551727.1
NFYB
nuclear transcription factor Y, beta
chr8_-_17555164 0.16 ENST00000297488.6
MTUS1
microtubule associated tumor suppressor 1
chr2_-_203103281 0.16 ENST00000392244.3
ENST00000409181.1
ENST00000409712.1
ENST00000409498.2
ENST00000409368.1
ENST00000392245.1
ENST00000392246.2
SUMO1
small ubiquitin-like modifier 1
chr12_+_69186125 0.16 ENST00000399333.3
AC124890.1
HCG1774533, isoform CRA_a; PRO2268; Uncharacterized protein
chr19_-_45663408 0.16 ENST00000317951.4
NKPD1
NTPase, KAP family P-loop domain containing 1
chr19_-_46145696 0.16 ENST00000588172.1
EML2
echinoderm microtubule associated protein like 2
chr13_+_73302047 0.15 ENST00000377814.2
ENST00000377815.3
ENST00000390667.5
BORA
bora, aurora kinase A activator
chr17_+_39346139 0.15 ENST00000398470.1
ENST00000318329.5
KRTAP9-1
keratin associated protein 9-1
chr4_+_8183793 0.15 ENST00000509119.1
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr15_+_68346501 0.15 ENST00000249636.6
PIAS1
protein inhibitor of activated STAT, 1
chr21_+_35552978 0.15 ENST00000428914.2
ENST00000609062.1
ENST00000609947.1
LINC00310
long intergenic non-protein coding RNA 310
chr8_-_141774467 0.15 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
PTK2
protein tyrosine kinase 2
chr4_-_83483094 0.15 ENST00000508701.1
ENST00000454948.3
TMEM150C
transmembrane protein 150C
chr4_-_83483360 0.15 ENST00000449862.2
TMEM150C
transmembrane protein 150C
chr15_+_43477580 0.14 ENST00000356633.5
CCNDBP1
cyclin D-type binding-protein 1
chr10_+_114710516 0.14 ENST00000542695.1
ENST00000346198.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr12_-_121734489 0.14 ENST00000412367.2
ENST00000402834.4
ENST00000404169.3
CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr16_+_2587965 0.14 ENST00000342085.4
ENST00000566659.1
PDPK1
3-phosphoinositide dependent protein kinase-1
chr19_-_12551849 0.14 ENST00000595562.1
ENST00000301547.5
CTD-3105H18.16
ZNF443
Uncharacterized protein
zinc finger protein 443
chr8_+_72755796 0.14 ENST00000524152.1
RP11-383H13.1
Protein LOC100132891; cDNA FLJ53548
chr3_+_38017264 0.14 ENST00000436654.1
CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr16_-_30457048 0.14 ENST00000500504.2
ENST00000542752.1
SEPHS2
selenophosphate synthetase 2
chr5_-_81046922 0.13 ENST00000514493.1
ENST00000320672.4
SSBP2
single-stranded DNA binding protein 2
chr6_+_54173227 0.13 ENST00000259782.4
ENST00000370864.3
TINAG
tubulointerstitial nephritis antigen
chr6_-_101329191 0.13 ENST00000324723.6
ENST00000369162.2
ENST00000522650.1
ASCC3
activating signal cointegrator 1 complex subunit 3
chr14_-_94759408 0.13 ENST00000554723.1
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr19_+_11877838 0.13 ENST00000357901.4
ENST00000454339.2
ZNF441
zinc finger protein 441
chr4_+_48485341 0.13 ENST00000273861.4
SLC10A4
solute carrier family 10, member 4
chr4_-_140477928 0.13 ENST00000274031.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr7_+_94536898 0.13 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr2_-_3504587 0.13 ENST00000415131.1
ADI1
acireductone dioxygenase 1
chr7_+_39605966 0.13 ENST00000223273.2
ENST00000448268.1
ENST00000432096.2
YAE1D1
Yae1 domain containing 1
chr6_-_41673552 0.13 ENST00000419574.1
ENST00000445214.1
TFEB
transcription factor EB
chr3_-_149093499 0.12 ENST00000472441.1
TM4SF1
transmembrane 4 L six family member 1
chr5_-_52405564 0.12 ENST00000510818.2
ENST00000396954.3
ENST00000508922.1
ENST00000361377.4
ENST00000582677.1
ENST00000584946.1
ENST00000450852.3
MOCS2
molybdenum cofactor synthesis 2
chr14_-_94759361 0.12 ENST00000393096.1
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr6_-_135818844 0.12 ENST00000524469.1
ENST00000367800.4
ENST00000327035.6
ENST00000457866.2
ENST00000265602.6
AHI1
Abelson helper integration site 1
chr10_+_51565188 0.12 ENST00000430396.2
ENST00000374087.4
ENST00000414907.2
NCOA4
nuclear receptor coactivator 4
chr12_-_31479045 0.12 ENST00000539409.1
ENST00000395766.1
FAM60A
family with sequence similarity 60, member A
chr1_-_242612779 0.12 ENST00000427495.1
PLD5
phospholipase D family, member 5
chr9_-_99180597 0.12 ENST00000375256.4
ZNF367
zinc finger protein 367
chr4_-_175443943 0.12 ENST00000296522.6
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr16_-_20817753 0.12 ENST00000389345.5
ENST00000300005.3
ENST00000357967.4
ENST00000569729.1
ERI2
ERI1 exoribonuclease family member 2
chr6_-_35656685 0.12 ENST00000539068.1
ENST00000540787.1
FKBP5
FK506 binding protein 5
chr11_-_8832521 0.12 ENST00000530438.1
ST5
suppression of tumorigenicity 5
chr5_+_118406796 0.11 ENST00000503802.1
DMXL1
Dmx-like 1
chr21_-_34143971 0.11 ENST00000290178.4
PAXBP1
PAX3 and PAX7 binding protein 1
chr13_+_76413852 0.11 ENST00000533809.2
LMO7
LIM domain 7
chr3_+_45636219 0.11 ENST00000273317.4
LIMD1
LIM domains containing 1
chr9_-_123638633 0.11 ENST00000456291.1
PHF19
PHD finger protein 19
chr21_-_30257669 0.11 ENST00000303775.5
ENST00000351429.3
N6AMT1
N-6 adenine-specific DNA methyltransferase 1 (putative)
chr9_-_123639304 0.11 ENST00000436309.1
PHF19
PHD finger protein 19
chr7_+_38217920 0.11 ENST00000396013.1
ENST00000440144.1
ENST00000453225.1
ENST00000429075.1
STARD3NL
STARD3 N-terminal like
chr12_+_95611569 0.11 ENST00000261219.6
ENST00000551472.1
ENST00000552821.1
VEZT
vezatin, adherens junctions transmembrane protein
chr17_+_8316442 0.11 ENST00000582812.1
NDEL1
nudE neurodevelopment protein 1-like 1
chr13_-_41837620 0.11 ENST00000379477.1
ENST00000452359.1
ENST00000379480.4
ENST00000430347.2
MTRF1
mitochondrial translational release factor 1
chr6_+_112375462 0.11 ENST00000361714.1
WISP3
WNT1 inducible signaling pathway protein 3
chr14_+_61995722 0.11 ENST00000556347.1
RP11-47I22.4
RP11-47I22.4
chr7_+_73442487 0.11 ENST00000380575.4
ENST00000380584.4
ENST00000458204.1
ENST00000357036.5
ENST00000417091.1
ENST00000429192.1
ENST00000442310.1
ENST00000380553.4
ENST00000380576.5
ENST00000428787.1
ENST00000320399.6
ELN
elastin
chr7_+_106810165 0.11 ENST00000468401.1
ENST00000497535.1
ENST00000485846.1
HBP1
HMG-box transcription factor 1
chr15_-_31283798 0.11 ENST00000435680.1
ENST00000425768.1
MTMR10
myotubularin related protein 10
chr9_-_139345270 0.11 ENST00000398335.1
SEC16A
SEC16 homolog A (S. cerevisiae)
chr1_-_225615599 0.11 ENST00000421383.1
ENST00000272163.4
LBR
lamin B receptor
chr9_-_86432547 0.10 ENST00000376365.3
ENST00000376371.2
GKAP1
G kinase anchoring protein 1
chr2_-_18770812 0.10 ENST00000359846.2
ENST00000304081.4
ENST00000600945.1
ENST00000532967.1
ENST00000444297.2
NT5C1B
NT5C1B-RDH14
5'-nucleotidase, cytosolic IB
NT5C1B-RDH14 readthrough
chr12_+_69004619 0.10 ENST00000250559.9
ENST00000393436.5
ENST00000425247.2
ENST00000489473.2
ENST00000422358.2
ENST00000541167.1
ENST00000538283.1
ENST00000341355.5
ENST00000537460.1
ENST00000450214.2
ENST00000545270.1
ENST00000538980.1
ENST00000542018.1
ENST00000543393.1
RAP1B
RAP1B, member of RAS oncogene family
chr19_+_11750566 0.10 ENST00000344893.3
ZNF833P
zinc finger protein 833, pseudogene
chr3_+_63897605 0.10 ENST00000487717.1
ATXN7
ataxin 7
chr7_+_38217818 0.10 ENST00000009041.7
ENST00000544203.1
ENST00000434197.1
STARD3NL
STARD3 N-terminal like
chr14_+_101359265 0.10 ENST00000599197.1
AL117190.3
Esophagus cancer-related gene-2 interaction susceptibility protein; Uncharacterized protein
chr17_-_77967433 0.10 ENST00000571872.1
TBC1D16
TBC1 domain family, member 16
chr5_-_132073111 0.10 ENST00000403231.1
KIF3A
kinesin family member 3A
chr6_-_32920794 0.10 ENST00000395305.3
ENST00000395303.3
ENST00000374843.4
ENST00000429234.1
HLA-DMA
XXbac-BPG181M17.5
major histocompatibility complex, class II, DM alpha
Uncharacterized protein
chr17_-_42767115 0.10 ENST00000315286.8
ENST00000588210.1
ENST00000457422.2
CCDC43
coiled-coil domain containing 43
chr2_-_190446738 0.10 ENST00000427419.1
ENST00000455320.1
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr2_-_152589670 0.10 ENST00000604864.1
ENST00000603639.1
NEB
nebulin
chr16_+_16484691 0.10 ENST00000344087.4
NPIPA7
nuclear pore complex interacting protein family, member A7
chr14_-_94856951 0.10 ENST00000553327.1
ENST00000556955.1
ENST00000557118.1
ENST00000440909.1
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr10_+_94608245 0.10 ENST00000443748.2
ENST00000260762.6
EXOC6
exocyst complex component 6
chr4_+_123653807 0.10 ENST00000314218.3
ENST00000542236.1
BBS12
Bardet-Biedl syndrome 12
chr1_-_70671216 0.10 ENST00000370952.3
LRRC40
leucine rich repeat containing 40
chr9_-_115653176 0.10 ENST00000374228.4
SLC46A2
solute carrier family 46, member 2
chr15_-_77197620 0.09 ENST00000565970.1
ENST00000563290.1
ENST00000565372.1
ENST00000564177.1
ENST00000568382.1
ENST00000563919.1
SCAPER
S-phase cyclin A-associated protein in the ER
chrX_-_148713365 0.09 ENST00000511776.1
ENST00000507237.1
TMEM185A
transmembrane protein 185A
chr4_+_88928777 0.09 ENST00000237596.2
PKD2
polycystic kidney disease 2 (autosomal dominant)
chr4_-_140477910 0.09 ENST00000404104.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr1_+_28844648 0.09 ENST00000373832.1
ENST00000373831.3
RCC1
regulator of chromosome condensation 1
chr2_-_86790472 0.09 ENST00000409727.1
CHMP3
charged multivesicular body protein 3
chr1_-_186649543 0.09 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr7_+_23637763 0.09 ENST00000410069.1
CCDC126
coiled-coil domain containing 126
chr14_+_62164340 0.09 ENST00000557538.1
ENST00000539097.1
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr2_+_198380289 0.09 ENST00000233892.4
ENST00000409916.1
MOB4
MOB family member 4, phocein
chr17_+_75396637 0.09 ENST00000590825.1
SEPT9
septin 9

Network of associatons between targets according to the STRING database.

First level regulatory network of PKNOX1_TGIF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.7 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.1 0.6 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 0.9 GO:0023021 termination of signal transduction(GO:0023021)
0.1 0.3 GO:0030070 insulin processing(GO:0030070)
0.1 0.3 GO:2000742 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.3 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.4 GO:0008218 bioluminescence(GO:0008218)
0.1 0.3 GO:0051836 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.1 0.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.2 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.7 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 0.2 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.1 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.2 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.2 GO:0061110 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.1 0.3 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.1 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.3 GO:0070295 renal water absorption(GO:0070295)
0.1 0.7 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.2 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.2 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.0 0.1 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.5 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.1 GO:0039007 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.0 0.2 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.4 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.2 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.5 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.1 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.1 GO:1904048 positive regulation of long term synaptic depression(GO:1900454) regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.0 0.3 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.1 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.1 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.4 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.1 GO:0050758 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.3 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0070839 divalent metal ion export(GO:0070839)
0.0 0.3 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.1 GO:0072194 detection of endogenous stimulus(GO:0009726) kidney smooth muscle tissue development(GO:0072194)
0.0 0.3 GO:0010629 negative regulation of gene expression(GO:0010629)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.8 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.0 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.0 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.1 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.0 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.0 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.3 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.0 GO:2000870 positive regulation of female gonad development(GO:2000196) regulation of progesterone secretion(GO:2000870)
0.0 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.3 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.0 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0043291 RAVE complex(GO:0043291)
0.0 0.1 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 0.5 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.5 GO:0042627 chylomicron(GO:0042627)
0.0 0.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.4 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.8 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0044754 autolysosome(GO:0044754)
0.0 0.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.2 0.7 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.2 0.5 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.7 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.1 0.3 GO:0019808 polyamine binding(GO:0019808)
0.1 0.7 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.3 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 0.3 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.1 0.6 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.2 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.3 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.7 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.1 0.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.7 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.1 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 0.4 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 0.2 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.1 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0031014 troponin T binding(GO:0031014)
0.0 0.2 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.0 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.0 GO:0001515 opioid peptide activity(GO:0001515)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.7 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.4 PID S1P S1P4 PATHWAY S1P4 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.8 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.9 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling