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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for PKNOX2

Z-value: 0.65

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Transcription factors associated with PKNOX2

Gene Symbol Gene ID Gene Info
PKNOX2
ENSG00000165495.11 PBX/knotted 1 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PKNOX2hg19_v2_chr11_+_125034586_1250346040.831.7e-01Click!

Activity profile of PKNOX2 motif

Sorted Z-values of PKNOX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_247171347 0.91 ENST00000339986.7
ENST00000487338.2
ZNF695
zinc finger protein 695
chr12_+_62654155 0.54 ENST00000312635.6
ENST00000393654.3
ENST00000549237.1
USP15
ubiquitin specific peptidase 15
chr3_-_52719888 0.49 ENST00000458294.1
PBRM1
polybromo 1
chr6_+_26124373 0.46 ENST00000377791.2
ENST00000602637.1
HIST1H2AC
histone cluster 1, H2ac
chr16_+_2880369 0.45 ENST00000572863.1
ZG16B
zymogen granule protein 16B
chr7_-_156803329 0.41 ENST00000252971.6
MNX1
motor neuron and pancreas homeobox 1
chr10_+_49514698 0.41 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
MAPK8
mitogen-activated protein kinase 8
chr11_+_6411636 0.40 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr6_+_111195973 0.38 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
AMD1
adenosylmethionine decarboxylase 1
chr12_+_69201923 0.36 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr18_-_52626622 0.36 ENST00000591504.1
CCDC68
coiled-coil domain containing 68
chrX_+_16804544 0.34 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr2_-_61765315 0.34 ENST00000406957.1
ENST00000401558.2
XPO1
exportin 1 (CRM1 homolog, yeast)
chr6_-_101329191 0.33 ENST00000324723.6
ENST00000369162.2
ENST00000522650.1
ASCC3
activating signal cointegrator 1 complex subunit 3
chrX_-_80377118 0.33 ENST00000373250.3
HMGN5
high mobility group nucleosome binding domain 5
chr10_-_124768300 0.33 ENST00000368886.5
IKZF5
IKAROS family zinc finger 5 (Pegasus)
chr1_+_154966058 0.31 ENST00000392487.1
LENEP
lens epithelial protein
chr3_-_33481835 0.30 ENST00000283629.3
UBP1
upstream binding protein 1 (LBP-1a)
chr9_-_123639445 0.29 ENST00000312189.6
PHF19
PHD finger protein 19
chr15_-_37392086 0.29 ENST00000561208.1
MEIS2
Meis homeobox 2
chr4_-_157892055 0.29 ENST00000422544.2
PDGFC
platelet derived growth factor C
chr4_-_83483094 0.28 ENST00000508701.1
ENST00000454948.3
TMEM150C
transmembrane protein 150C
chr8_-_99837856 0.27 ENST00000518165.1
ENST00000419617.2
STK3
serine/threonine kinase 3
chr11_+_120207787 0.27 ENST00000397843.2
ENST00000356641.3
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr11_+_6411670 0.27 ENST00000530395.1
ENST00000527275.1
SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr15_+_96904487 0.26 ENST00000600790.1
AC087477.1
Uncharacterized protein
chr9_-_33447584 0.26 ENST00000297991.4
AQP3
aquaporin 3 (Gill blood group)
chrX_-_80377162 0.25 ENST00000430960.1
ENST00000447319.1
HMGN5
high mobility group nucleosome binding domain 5
chr3_+_113667354 0.24 ENST00000491556.1
ZDHHC23
zinc finger, DHHC-type containing 23
chr2_+_202316392 0.24 ENST00000194530.3
ENST00000392249.2
STRADB
STE20-related kinase adaptor beta
chr4_+_169418195 0.23 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr3_+_32147997 0.23 ENST00000282541.5
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr5_-_81046904 0.23 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chr8_+_72755796 0.22 ENST00000524152.1
RP11-383H13.1
Protein LOC100132891; cDNA FLJ53548
chr10_+_94608245 0.22 ENST00000443748.2
ENST00000260762.6
EXOC6
exocyst complex component 6
chr8_+_57124245 0.22 ENST00000521831.1
ENST00000355315.3
ENST00000303759.3
ENST00000517636.1
ENST00000517933.1
ENST00000518801.1
ENST00000523975.1
ENST00000396723.5
ENST00000523061.1
ENST00000521524.1
CHCHD7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr2_+_191208601 0.22 ENST00000413239.1
ENST00000431594.1
ENST00000444194.1
INPP1
inositol polyphosphate-1-phosphatase
chr5_-_81046922 0.22 ENST00000514493.1
ENST00000320672.4
SSBP2
single-stranded DNA binding protein 2
chr11_-_8832521 0.22 ENST00000530438.1
ST5
suppression of tumorigenicity 5
chr9_-_132805430 0.21 ENST00000446176.2
ENST00000355681.3
ENST00000420781.1
FNBP1
formin binding protein 1
chr10_-_101945771 0.21 ENST00000370408.2
ENST00000407654.3
ERLIN1
ER lipid raft associated 1
chr9_-_123639304 0.21 ENST00000436309.1
PHF19
PHD finger protein 19
chr17_+_68071389 0.21 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr4_-_157892498 0.20 ENST00000502773.1
PDGFC
platelet derived growth factor C
chr4_+_140222609 0.20 ENST00000296543.5
ENST00000398947.1
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr7_-_104909435 0.20 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr5_+_118407053 0.19 ENST00000311085.8
ENST00000539542.1
DMXL1
Dmx-like 1
chr4_+_166300084 0.19 ENST00000402744.4
CPE
carboxypeptidase E
chr18_-_54318353 0.19 ENST00000590954.1
ENST00000540155.1
TXNL1
thioredoxin-like 1
chr16_-_1275257 0.19 ENST00000234798.4
TPSG1
tryptase gamma 1
chr14_+_61995722 0.18 ENST00000556347.1
RP11-47I22.4
RP11-47I22.4
chr12_+_62654119 0.18 ENST00000353364.3
ENST00000549523.1
ENST00000280377.5
USP15
ubiquitin specific peptidase 15
chr17_-_29151686 0.17 ENST00000544695.1
CRLF3
cytokine receptor-like factor 3
chr8_+_72755367 0.17 ENST00000537896.1
RP11-383H13.1
Protein LOC100132891; cDNA FLJ53548
chr17_-_27405875 0.17 ENST00000359450.6
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr4_+_128703295 0.17 ENST00000296464.4
ENST00000508549.1
HSPA4L
heat shock 70kDa protein 4-like
chr3_+_14474178 0.17 ENST00000452775.1
SLC6A6
solute carrier family 6 (neurotransmitter transporter), member 6
chr6_+_150070831 0.17 ENST00000367380.5
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr6_-_116575226 0.17 ENST00000420283.1
TSPYL4
TSPY-like 4
chr2_+_64681103 0.16 ENST00000464281.1
LGALSL
lectin, galactoside-binding-like
chr16_-_30457048 0.16 ENST00000500504.2
ENST00000542752.1
SEPHS2
selenophosphate synthetase 2
chr5_-_52405564 0.16 ENST00000510818.2
ENST00000396954.3
ENST00000508922.1
ENST00000361377.4
ENST00000582677.1
ENST00000584946.1
ENST00000450852.3
MOCS2
molybdenum cofactor synthesis 2
chr6_-_149867122 0.15 ENST00000253329.2
PPIL4
peptidylprolyl isomerase (cyclophilin)-like 4
chr16_+_2880254 0.15 ENST00000570670.1
ZG16B
zymogen granule protein 16B
chr2_-_61765732 0.15 ENST00000443240.1
ENST00000436018.1
XPO1
exportin 1 (CRM1 homolog, yeast)
chr3_-_101395936 0.15 ENST00000461821.1
ZBTB11
zinc finger and BTB domain containing 11
chr3_-_3221358 0.15 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
CRBN
cereblon
chr13_-_48575376 0.15 ENST00000434484.1
SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr1_-_54872059 0.14 ENST00000371320.3
SSBP3
single stranded DNA binding protein 3
chr22_-_30234218 0.14 ENST00000307790.3
ENST00000542393.1
ENST00000397771.2
ASCC2
activating signal cointegrator 1 complex subunit 2
chr6_+_17600576 0.14 ENST00000259963.3
FAM8A1
family with sequence similarity 8, member A1
chr5_-_81046841 0.13 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2
single-stranded DNA binding protein 2
chr9_-_140142181 0.13 ENST00000484720.1
FAM166A
family with sequence similarity 166, member A
chr6_-_101329157 0.13 ENST00000369143.2
ASCC3
activating signal cointegrator 1 complex subunit 3
chr1_-_100598444 0.13 ENST00000535161.1
ENST00000287482.5
SASS6
spindle assembly 6 homolog (C. elegans)
chr2_-_74780176 0.13 ENST00000409549.1
LOXL3
lysyl oxidase-like 3
chr3_-_127541679 0.13 ENST00000265052.5
MGLL
monoglyceride lipase
chr9_+_128510454 0.12 ENST00000491787.3
ENST00000447726.2
PBX3
pre-B-cell leukemia homeobox 3
chr14_-_21994525 0.11 ENST00000538754.1
SALL2
spalt-like transcription factor 2
chr2_-_73460334 0.11 ENST00000258083.2
PRADC1
protease-associated domain containing 1
chr20_+_43514320 0.11 ENST00000372839.3
ENST00000428262.1
ENST00000445830.1
YWHAB
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
chr2_+_113033164 0.11 ENST00000409871.1
ENST00000343936.4
ZC3H6
zinc finger CCCH-type containing 6
chr17_+_78518617 0.11 ENST00000537330.1
ENST00000570891.1
RPTOR
regulatory associated protein of MTOR, complex 1
chr6_+_108881012 0.11 ENST00000343882.6
FOXO3
forkhead box O3
chr17_+_39868577 0.11 ENST00000329402.3
GAST
gastrin
chr5_+_118406796 0.10 ENST00000503802.1
DMXL1
Dmx-like 1
chr18_-_54305658 0.10 ENST00000586262.1
ENST00000217515.6
TXNL1
thioredoxin-like 1
chr17_+_68071458 0.09 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr9_-_123639600 0.09 ENST00000373896.3
PHF19
PHD finger protein 19
chr8_+_133787586 0.09 ENST00000395379.1
ENST00000395386.2
ENST00000337920.4
PHF20L1
PHD finger protein 20-like 1
chr2_+_191208196 0.09 ENST00000392329.2
ENST00000322522.4
ENST00000430311.1
ENST00000541441.1
INPP1
inositol polyphosphate-1-phosphatase
chr11_-_64013288 0.09 ENST00000542235.1
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr2_-_202316260 0.09 ENST00000332624.3
TRAK2
trafficking protein, kinesin binding 2
chr10_+_51565188 0.08 ENST00000430396.2
ENST00000374087.4
ENST00000414907.2
NCOA4
nuclear receptor coactivator 4
chr9_-_140142222 0.08 ENST00000344774.4
ENST00000388932.2
FAM166A
family with sequence similarity 166, member A
chr17_-_3499125 0.08 ENST00000399759.3
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr3_+_46742823 0.08 ENST00000326431.3
TMIE
transmembrane inner ear
chr2_-_190446738 0.08 ENST00000427419.1
ENST00000455320.1
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr12_+_49621658 0.07 ENST00000541364.1
TUBA1C
tubulin, alpha 1c
chr2_+_64681219 0.07 ENST00000238875.5
LGALSL
lectin, galactoside-binding-like
chr5_-_132073111 0.07 ENST00000403231.1
KIF3A
kinesin family member 3A
chr3_-_127541194 0.06 ENST00000453507.2
MGLL
monoglyceride lipase
chr12_-_121734489 0.06 ENST00000412367.2
ENST00000402834.4
ENST00000404169.3
CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr17_-_40337470 0.06 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr4_-_157892167 0.06 ENST00000541126.1
PDGFC
platelet derived growth factor C
chr5_+_72509751 0.06 ENST00000515556.1
ENST00000513379.1
ENST00000427584.2
RP11-60A8.1
RP11-60A8.1
chr19_+_41281060 0.06 ENST00000594436.1
ENST00000597784.1
MIA
melanoma inhibitory activity
chr14_-_21994337 0.06 ENST00000537235.1
ENST00000450879.2
SALL2
spalt-like transcription factor 2
chrX_-_39923656 0.05 ENST00000413905.1
BCOR
BCL6 corepressor
chr15_+_57668695 0.05 ENST00000281282.5
CGNL1
cingulin-like 1
chr15_+_68346501 0.05 ENST00000249636.6
PIAS1
protein inhibitor of activated STAT, 1
chr4_-_100871506 0.05 ENST00000296417.5
H2AFZ
H2A histone family, member Z
chr19_+_7733929 0.05 ENST00000221515.2
RETN
resistin
chr10_+_28822636 0.05 ENST00000442148.1
ENST00000448193.1
WAC
WW domain containing adaptor with coiled-coil
chr2_+_113321939 0.05 ENST00000458012.2
POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chr11_-_1782625 0.05 ENST00000438213.1
CTSD
cathepsin D
chr6_-_84418841 0.05 ENST00000369694.2
ENST00000195649.6
SNAP91
synaptosomal-associated protein, 91kDa
chr1_+_66258846 0.04 ENST00000341517.4
PDE4B
phosphodiesterase 4B, cAMP-specific
chr6_+_150070857 0.04 ENST00000544496.1
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr9_-_99637820 0.04 ENST00000289032.8
ENST00000535338.1
ZNF782
zinc finger protein 782
chr6_+_37225540 0.04 ENST00000373491.3
TBC1D22B
TBC1 domain family, member 22B
chr2_-_18770812 0.04 ENST00000359846.2
ENST00000304081.4
ENST00000600945.1
ENST00000532967.1
ENST00000444297.2
NT5C1B
NT5C1B-RDH14
5'-nucleotidase, cytosolic IB
NT5C1B-RDH14 readthrough
chr16_+_50776021 0.03 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
CYLD
cylindromatosis (turban tumor syndrome)
chr9_+_133454943 0.03 ENST00000319725.9
FUBP3
far upstream element (FUSE) binding protein 3
chrX_-_148713440 0.03 ENST00000536359.1
ENST00000316916.8
TMEM185A
transmembrane protein 185A
chr16_+_2880296 0.03 ENST00000571723.1
ZG16B
zymogen granule protein 16B
chr1_-_35658736 0.02 ENST00000357214.5
SFPQ
splicing factor proline/glutamine-rich
chr13_+_20268547 0.02 ENST00000601204.1
AL354808.2
AL354808.2
chr3_-_52719912 0.02 ENST00000420148.1
PBRM1
polybromo 1
chr2_-_219524193 0.01 ENST00000450560.1
ENST00000449707.1
ENST00000432460.1
ENST00000411696.2
ZNF142
zinc finger protein 142
chr11_-_46867780 0.01 ENST00000529230.1
ENST00000415402.1
ENST00000312055.5
CKAP5
cytoskeleton associated protein 5
chr17_+_8316442 0.01 ENST00000582812.1
NDEL1
nudE neurodevelopment protein 1-like 1
chrX_+_41548220 0.01 ENST00000378142.4
GPR34
G protein-coupled receptor 34
chr2_-_202316169 0.01 ENST00000430254.1
TRAK2
trafficking protein, kinesin binding 2
chr17_+_38474489 0.01 ENST00000394089.2
ENST00000425707.3
RARA
retinoic acid receptor, alpha
chr22_+_20905269 0.01 ENST00000457322.1
MED15
mediator complex subunit 15
chr3_+_23244780 0.01 ENST00000396703.1
UBE2E2
ubiquitin-conjugating enzyme E2E 2
chr10_+_70661014 0.00 ENST00000373585.3
DDX50
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr2_+_219524473 0.00 ENST00000439945.1
ENST00000431802.1
BCS1L
BC1 (ubiquinol-cytochrome c reductase) synthesis-like

Network of associatons between targets according to the STRING database.

First level regulatory network of PKNOX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.4 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.1 0.4 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.4 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.7 GO:0023021 termination of signal transduction(GO:0023021)
0.1 0.2 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.2 GO:0030070 insulin processing(GO:0030070)
0.1 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.2 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.6 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.3 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.6 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.1 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.2 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.3 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0070839 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:2000870 positive regulation of female gonad development(GO:2000196) regulation of progesterone secretion(GO:2000870)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.6 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.2 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.1 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.0 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.1 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.0 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.5 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.2 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0043291 RAVE complex(GO:0043291)
0.1 0.2 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 0.5 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.7 GO:0042599 lamellar body(GO:0042599)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.4 GO:0019808 polyamine binding(GO:0019808)
0.1 0.4 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 0.7 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.2 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 0.3 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.3 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.1 0.2 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.2 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.1 0.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.5 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.6 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.7 PID TRAIL PATHWAY TRAIL signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.3 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1