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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for POU5F1_POU2F3

Z-value: 1.00

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Transcription factors associated with POU5F1_POU2F3

Gene Symbol Gene ID Gene Info
ENSG00000204531.11 POU class 5 homeobox 1
ENSG00000137709.5 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU5F1hg19_v2_chr6_-_31138439_311384750.307.0e-01Click!
POU2F3hg19_v2_chr11_+_120107344_120107351-0.148.6e-01Click!

Activity profile of POU5F1_POU2F3 motif

Sorted Z-values of POU5F1_POU2F3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_80457385 1.33 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
high mobility group nucleosome binding domain 5
chr17_+_38171681 0.96 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
colony stimulating factor 3 (granulocyte)
chr17_+_38171614 0.81 ENST00000583218.1
ENST00000394149.3
colony stimulating factor 3 (granulocyte)
chr10_+_91061712 0.76 ENST00000371826.3
interferon-induced protein with tetratricopeptide repeats 2
chr12_+_113344582 0.71 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr6_-_26124138 0.70 ENST00000314332.5
ENST00000396984.1
histone cluster 1, H2bc
chr18_+_77867177 0.64 ENST00000560752.1
ADNP homeobox 2
chr12_+_113344811 0.63 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_+_113354341 0.57 ENST00000553152.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr6_-_32784687 0.57 ENST00000447394.1
ENST00000438763.2
major histocompatibility complex, class II, DO beta
chr8_+_39759794 0.55 ENST00000518804.1
ENST00000519154.1
ENST00000522495.1
ENST00000522840.1
indoleamine 2,3-dioxygenase 1
chr10_+_106113515 0.54 ENST00000369704.3
ENST00000312902.5
coiled-coil domain containing 147
chr12_+_93096619 0.51 ENST00000397833.3
chromosome 12 open reading frame 74
chr2_+_5832799 0.50 ENST00000322002.3
SRY (sex determining region Y)-box 11
chr6_+_26217159 0.47 ENST00000303910.2
histone cluster 1, H2ae
chr19_-_44123734 0.47 ENST00000598676.1
zinc finger protein 428
chr12_+_113344755 0.44 ENST00000550883.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr19_-_1021113 0.43 ENST00000333175.5
ENST00000356663.3
transmembrane protein 259
chr14_-_23446003 0.43 ENST00000553911.1
ajuba LIM protein
chr12_-_7245018 0.43 ENST00000543835.1
ENST00000535233.2
complement component 1, r subcomponent
chr7_+_26438187 0.43 ENST00000439120.1
ENST00000430548.1
ENST00000421862.1
ENST00000449537.1
ENST00000420774.1
ENST00000418758.2
AC004540.5
chr16_+_56642489 0.42 ENST00000561491.1
metallothionein 2A
chr12_+_93115281 0.41 ENST00000549856.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr2_-_177684007 0.41 ENST00000451851.1
AC092162.1
chr7_-_17500294 0.41 ENST00000439046.1
AC019117.2
chr7_-_100183742 0.41 ENST00000310300.6
leucine-rich repeats and calponin homology (CH) domain containing 4
chr12_-_7245080 0.41 ENST00000541042.1
ENST00000540242.1
complement component 1, r subcomponent
chr6_-_26033796 0.39 ENST00000259791.2
histone cluster 1, H2ab
chr5_-_175965008 0.39 ENST00000537487.1
ring finger protein 44
chrX_+_154114635 0.39 ENST00000369446.2
coagulation factor VIII-associated 1
chr11_+_313503 0.39 ENST00000528780.1
ENST00000328221.5
interferon induced transmembrane protein 1
chr9_-_32526299 0.39 ENST00000379882.1
ENST00000379883.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr3_-_107777208 0.38 ENST00000398258.3
CD47 molecule
chr6_-_83775442 0.38 ENST00000369745.5
ubiquitin protein ligase E3D
chr1_+_28206150 0.36 ENST00000456990.1
thymocyte selection associated family member 2
chr12_-_7245152 0.36 ENST00000542220.2
complement component 1, r subcomponent
chr2_-_158182105 0.35 ENST00000409925.1
ermin, ERM-like protein
chr11_+_12108410 0.34 ENST00000527997.1
RP13-631K18.5
chr1_+_17575584 0.34 ENST00000375460.3
peptidyl arginine deiminase, type III
chr6_+_131571535 0.34 ENST00000474850.2
A kinase (PRKA) anchor protein 7
chr1_+_79115503 0.34 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
interferon-induced protein 44
chr2_-_158182322 0.33 ENST00000420719.2
ENST00000409216.1
ermin, ERM-like protein
chr15_+_67358163 0.33 ENST00000327367.4
SMAD family member 3
chr12_-_123187890 0.32 ENST00000328880.5
hydroxycarboxylic acid receptor 2
chr3_-_122283100 0.32 ENST00000492382.1
ENST00000462315.1
poly (ADP-ribose) polymerase family, member 9
chr19_+_39903185 0.31 ENST00000409794.3
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr6_+_26273144 0.31 ENST00000377733.2
histone cluster 1, H2bi
chr11_-_115375107 0.30 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
cell adhesion molecule 1
chr20_+_34556488 0.30 ENST00000373973.3
ENST00000349339.1
ENST00000538900.1
cyclic nucleotide binding domain containing 2
chr2_-_102003987 0.30 ENST00000324768.5
cellular repressor of E1A-stimulated genes 2
chr12_+_93096759 0.30 ENST00000544406.2
chromosome 12 open reading frame 74
chr1_-_149783914 0.30 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
histone cluster 2, H2bf
chr9_+_35658262 0.30 ENST00000378407.3
ENST00000378406.1
ENST00000426546.2
ENST00000327351.2
ENST00000421582.2
coiled-coil domain containing 107
chr12_-_56359802 0.29 ENST00000548803.1
ENST00000449260.2
ENST00000550447.1
ENST00000547137.1
ENST00000546543.1
ENST00000550464.1
premelanosome protein
chr14_+_65007177 0.29 ENST00000247207.6
heat shock 70kDa protein 2
chr9_-_35658007 0.28 ENST00000602361.1
RNA component of mitochondrial RNA processing endoribonuclease
chr5_+_49961727 0.28 ENST00000505697.2
ENST00000503750.2
ENST00000514342.2
poly (ADP-ribose) polymerase family, member 8
chr5_+_49962772 0.28 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
poly (ADP-ribose) polymerase family, member 8
chr3_-_122283079 0.27 ENST00000471785.1
ENST00000466126.1
poly (ADP-ribose) polymerase family, member 9
chr5_+_73109339 0.27 ENST00000296799.4
Rho guanine nucleotide exchange factor (GEF) 28
chrX_+_154611749 0.27 ENST00000369505.3
coagulation factor VIII-associated 2
chr17_-_19015945 0.27 ENST00000573866.2
small nucleolar RNA, C/D box 3D
chr19_-_1132207 0.26 ENST00000438103.2
strawberry notch homolog 2 (Drosophila)
chr15_+_41245160 0.26 ENST00000444189.2
ENST00000446533.3
ChaC, cation transport regulator homolog 1 (E. coli)
chr7_+_129007964 0.26 ENST00000460109.1
ENST00000474594.1
ENST00000446212.1
adenosylhomocysteinase-like 2
chr19_+_18726786 0.26 ENST00000594709.1
transmembrane protein 59-like
chr9_+_132099158 0.26 ENST00000444125.1
RP11-65J3.1
chr16_+_82660635 0.25 ENST00000567445.1
ENST00000446376.2
cadherin 13
chr1_-_60392452 0.25 ENST00000371204.3
cytochrome P450, family 2, subfamily J, polypeptide 2
chr6_+_83072923 0.25 ENST00000535040.1
trophoblast glycoprotein
chrX_+_33744503 0.25 ENST00000439992.1
RP11-305F18.1
chr22_+_43011247 0.25 ENST00000602478.1
RNA, U12 small nuclear
chr16_+_56716336 0.25 ENST00000394485.4
ENST00000562939.1
metallothionein 1X
chr3_-_46068969 0.25 ENST00000542109.1
ENST00000395946.2
chemokine (C motif) receptor 1
chr12_-_7245125 0.24 ENST00000542285.1
ENST00000540610.1
complement component 1, r subcomponent
chr6_-_27782548 0.24 ENST00000333151.3
histone cluster 1, H2aj
chr11_-_124806297 0.24 ENST00000298251.4
hepatic and glial cell adhesion molecule
chr17_+_19091325 0.24 ENST00000584923.1
small nucleolar RNA, C/D box 3A
chr3_-_172241250 0.24 ENST00000420541.2
ENST00000241261.2
tumor necrosis factor (ligand) superfamily, member 10
chr15_-_60695071 0.23 ENST00000557904.1
annexin A2
chr18_-_59274139 0.23 ENST00000586949.1
RP11-879F14.2
chr6_-_41254403 0.23 ENST00000589614.1
ENST00000334475.6
ENST00000591620.1
ENST00000244709.4
triggering receptor expressed on myeloid cells 1
chr11_-_18258342 0.23 ENST00000278222.4
serum amyloid A4, constitutive
chr12_-_116714564 0.23 ENST00000548743.1
mediator complex subunit 13-like
chr8_+_58658679 0.23 ENST00000518934.1
CTD-2339F6.1
chr7_-_93520191 0.22 ENST00000545378.1
tissue factor pathway inhibitor 2
chr6_+_83073334 0.22 ENST00000369750.3
trophoblast glycoprotein
chr7_-_93520259 0.22 ENST00000222543.5
tissue factor pathway inhibitor 2
chr3_+_182983126 0.22 ENST00000481531.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr17_+_40118805 0.22 ENST00000591072.1
ENST00000587679.1
ENST00000393888.1
ENST00000441615.2
2',3'-cyclic nucleotide 3' phosphodiesterase
chr3_-_122283424 0.22 ENST00000477522.2
ENST00000360356.2
poly (ADP-ribose) polymerase family, member 9
chr18_+_63417864 0.22 ENST00000536984.2
cadherin 7, type 2
chr7_+_141478242 0.22 ENST00000247881.2
taste receptor, type 2, member 4
chr6_+_31588478 0.22 ENST00000376007.4
ENST00000376033.2
proline-rich coiled-coil 2A
chr11_+_69455855 0.22 ENST00000227507.2
ENST00000536559.1
cyclin D1
chr7_+_47834908 0.22 ENST00000418326.2
chromosome 7 open reading frame 69
chr7_+_141490017 0.21 ENST00000247883.4
taste receptor, type 2, member 5
chr19_-_18508396 0.21 ENST00000595840.1
ENST00000339007.3
leucine rich repeat containing 25
chr19_-_44124019 0.21 ENST00000300811.3
zinc finger protein 428
chr4_+_70916119 0.21 ENST00000246896.3
ENST00000511674.1
histatin 1
chr12_+_122064673 0.21 ENST00000537188.1
ORAI calcium release-activated calcium modulator 1
chr19_-_23456996 0.21 ENST00000594653.1
RP11-15H20.7
chr2_+_47922958 0.21 ENST00000606499.1
mutS homolog 6
chr4_-_95264008 0.21 ENST00000295256.5
hematopoietic prostaglandin D synthase
chr8_-_23712312 0.21 ENST00000290271.2
stanniocalcin 1
chr2_-_68547061 0.21 ENST00000263655.3
cannabinoid receptor interacting protein 1
chr7_-_33080506 0.21 ENST00000381626.2
ENST00000409467.1
ENST00000449201.1
5'-nucleotidase, cytosolic IIIA
chr13_-_41111323 0.21 ENST00000595486.1
Uncharacterized protein
chr4_+_2043689 0.21 ENST00000382878.3
ENST00000409248.4
chromosome 4 open reading frame 48
chr14_+_79745746 0.20 ENST00000281127.7
neurexin 3
chr22_+_46449674 0.20 ENST00000381051.2
hsa-mir-4763
chr14_+_71679350 0.20 ENST00000553621.1
RP6-91H8.1
chr7_+_22766766 0.20 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
interleukin 6 (interferon, beta 2)
chr4_-_176733897 0.20 ENST00000393658.2
glycoprotein M6A
chr10_+_81891416 0.20 ENST00000372270.2
placenta-specific 9
chr17_+_27369918 0.19 ENST00000323372.4
pipecolic acid oxidase
chr2_+_233734994 0.19 ENST00000331342.2
chromosome 2 open reading frame 82
chr17_-_38978847 0.19 ENST00000269576.5
keratin 10
chr2_-_207082748 0.19 ENST00000407325.2
ENST00000411719.1
G protein-coupled receptor 1
chr19_-_18392422 0.19 ENST00000252818.3
jun D proto-oncogene
chr3_+_183817967 0.19 ENST00000335304.2
ENST00000431041.1
ENST00000436361.2
ENST00000440596.2
5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
chr1_-_153348067 0.19 ENST00000368737.3
S100 calcium binding protein A12
chr3_-_48594248 0.19 ENST00000545984.1
ENST00000232375.3
ENST00000416568.1
ENST00000383734.2
ENST00000541519.1
ENST00000412035.1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr5_-_73936544 0.19 ENST00000509127.2
ectodermal-neural cortex 1 (with BTB domain)
chr20_-_56265680 0.19 ENST00000414037.1
prostate transmembrane protein, androgen induced 1
chr5_+_159895275 0.18 ENST00000517927.1
microRNA 146a
chr3_-_185270383 0.18 ENST00000296252.4
lipase, member H
chr6_+_166945369 0.18 ENST00000598601.1
CDNA FLJ25492 fis, clone CBR01389; Uncharacterized protein
chr6_+_31895480 0.18 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr6_+_27833034 0.18 ENST00000357320.2
histone cluster 1, H2al
chr1_+_45140360 0.18 ENST00000418644.1
ENST00000458657.2
ENST00000441519.1
ENST00000535358.1
ENST00000445071.1
chromosome 1 open reading frame 228
chr19_-_17516449 0.17 ENST00000252593.6
bone marrow stromal cell antigen 2
chr6_+_31895467 0.17 ENST00000556679.1
ENST00000456570.1
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr17_-_38520067 0.17 ENST00000337376.4
ENST00000578689.1
gap junction protein, delta 3, 31.9kDa
chr16_-_88752889 0.17 ENST00000332281.5
snail family zinc finger 3
chrX_-_154688276 0.17 ENST00000369445.2
coagulation factor VIII-associated 3
chr7_+_13141010 0.17 ENST00000443947.1
AC011288.2
chr17_-_63557309 0.17 ENST00000580513.1
axin 2
chr15_+_63334831 0.17 ENST00000288398.6
ENST00000358278.3
ENST00000560445.1
ENST00000403994.3
ENST00000357980.4
ENST00000559556.1
ENST00000559397.1
ENST00000267996.7
ENST00000560970.1
tropomyosin 1 (alpha)
chr11_+_64085560 0.17 ENST00000265462.4
ENST00000352435.4
ENST00000347941.4
peroxiredoxin 5
chr5_+_140593509 0.17 ENST00000341948.4
protocadherin beta 13
chr5_-_39270725 0.17 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYN binding protein
chr1_-_217262969 0.17 ENST00000361525.3
estrogen-related receptor gamma
chr16_+_82660560 0.17 ENST00000268613.10
ENST00000565636.1
ENST00000431540.3
ENST00000428848.3
cadherin 13
chr14_+_55033815 0.17 ENST00000554335.1
sterile alpha motif domain containing 4A
chr1_-_8000872 0.17 ENST00000377507.3
tumor necrosis factor receptor superfamily, member 9
chr4_-_99578789 0.17 ENST00000511651.1
ENST00000505184.1
tetraspanin 5
chr12_+_7053228 0.17 ENST00000540506.2
chromosome 12 open reading frame 57
chr22_+_44319648 0.17 ENST00000423180.2
patatin-like phospholipase domain containing 3
chr1_-_149858227 0.17 ENST00000369155.2
histone cluster 2, H2be
chr15_-_80263506 0.17 ENST00000335661.6
BCL2-related protein A1
chr3_+_122283064 0.17 ENST00000296161.4
deltex 3-like (Drosophila)
chr5_-_138780159 0.17 ENST00000512473.1
ENST00000515581.1
ENST00000515277.1
DnaJ (Hsp40) homolog, subfamily C, member 18
chr15_+_67458357 0.16 ENST00000537194.2
SMAD family member 3
chr1_+_164528437 0.16 ENST00000485769.1
pre-B-cell leukemia homeobox 1
chr18_+_18943554 0.16 ENST00000580732.2
growth regulation by estrogen in breast cancer-like
chrX_-_84634737 0.16 ENST00000262753.4
premature ovarian failure, 1B
chr1_+_185126598 0.16 ENST00000450350.1
SWT1 RNA endoribonuclease homolog (S. cerevisiae)
chr6_-_143266297 0.16 ENST00000367603.2
human immunodeficiency virus type I enhancer binding protein 2
chrX_+_134654540 0.16 ENST00000370752.4
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr4_+_71091786 0.16 ENST00000317987.5
follicular dendritic cell secreted protein
chr9_-_131940526 0.16 ENST00000372491.2
immediate early response 5-like
chr21_-_16125773 0.16 ENST00000454128.2
AF127936.3
chr8_-_112248400 0.16 ENST00000519506.1
ENST00000522778.1
RP11-946L20.4
chr12_+_43086018 0.16 ENST00000550177.1
RP11-25I15.3
chr12_+_72080253 0.16 ENST00000549735.1
transmembrane protein 19
chr11_+_32154200 0.16 ENST00000525133.1
RP1-65P5.5
chr18_-_52989525 0.16 ENST00000457482.3
transcription factor 4
chr6_+_160693591 0.16 ENST00000419196.1
RP1-276N6.2
chr3_-_185270342 0.16 ENST00000424591.2
lipase, member H
chr8_-_23282797 0.15 ENST00000524144.1
lysyl oxidase-like 2
chr16_-_75285380 0.15 ENST00000393420.6
ENST00000162330.5
breast cancer anti-estrogen resistance 1
chr22_-_24096630 0.15 ENST00000248948.3
pre-B lymphocyte 3
chr19_-_19281054 0.15 ENST00000424583.2
ENST00000410050.1
ENST00000409224.1
ENST00000409447.2
myocyte enhancer factor 2B
chr17_+_40118773 0.15 ENST00000472031.1
2',3'-cyclic nucleotide 3' phosphodiesterase
chr12_-_95611149 0.15 ENST00000549499.1
ENST00000343958.4
ENST00000546711.1
FYVE, RhoGEF and PH domain containing 6
chr16_-_11730213 0.15 ENST00000576334.1
ENST00000574848.1
lipopolysaccharide-induced TNF factor
chr8_+_23386305 0.15 ENST00000519973.1
solute carrier family 25 (mitochondrial iron transporter), member 37
chr1_-_213020991 0.15 ENST00000332912.3
chromosome 1 open reading frame 227
chrX_+_23801280 0.15 ENST00000379251.3
ENST00000379253.3
ENST00000379254.1
ENST00000379270.4
spermidine/spermine N1-acetyltransferase 1
chr22_+_21987005 0.15 ENST00000607942.1
ENST00000425975.1
ENST00000292779.3
coiled-coil domain containing 116
chr6_+_24357131 0.15 ENST00000274766.1
kidney associated antigen 1
chr1_-_98515395 0.14 ENST00000424528.2
MIR137 host gene (non-protein coding)
chr12_+_132312931 0.14 ENST00000360564.1
ENST00000545671.1
ENST00000545790.1
matrix metallopeptidase 17 (membrane-inserted)
chr17_-_10707410 0.14 ENST00000581851.1
long intergenic non-protein coding RNA 675
chr1_+_244227632 0.14 ENST00000598000.1
Uncharacterized protein; cDNA FLJ42623 fis, clone BRACE3015894
chr11_-_64511575 0.14 ENST00000431822.1
ENST00000377486.3
ENST00000394432.3
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr2_+_242127924 0.14 ENST00000402530.3
ENST00000274979.8
ENST00000402430.3
anoctamin 7
chr19_-_3971050 0.14 ENST00000545797.2
ENST00000596311.1
death-associated protein kinase 3
chr22_-_36556821 0.14 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
apolipoprotein L, 3
chr7_+_47834880 0.14 ENST00000258776.4
chromosome 7 open reading frame 69
chr19_+_38880695 0.14 ENST00000587947.1
ENST00000338502.4
sprouty-related, EVH1 domain containing 3
chr7_-_47520869 0.14 ENST00000415929.1
tensin 3
chr1_-_196577489 0.14 ENST00000609185.1
ENST00000451324.2
ENST00000367433.5
ENST00000367431.4
potassium channel, subfamily T, member 2
chr5_+_158527485 0.14 ENST00000517335.1
RP11-175K6.1
chr15_+_65337708 0.14 ENST00000334287.2
solute carrier family 51, beta subunit
chr17_+_73084038 0.14 ENST00000578376.1
ENST00000329783.4
solute carrier family 16 (monocarboxylate transporter), member 5
chr9_-_15472730 0.14 ENST00000481862.1
PC4 and SFRS1 interacting protein 1
chrX_+_36053908 0.14 ENST00000378660.2
calponin homology domain containing 2
chr5_-_90610200 0.14 ENST00000511918.1
ENST00000513626.1
ENST00000607854.1
lung cancer associated transcript 1 (non-protein coding)
RP11-213H15.4

Network of associatons between targets according to the STRING database.

First level regulatory network of POU5F1_POU2F3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 GO:0030223 neutrophil differentiation(GO:0030223)
0.2 0.6 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.2 0.6 GO:0036269 swimming behavior(GO:0036269)
0.2 0.5 GO:0061386 closure of optic fissure(GO:0061386)
0.1 0.4 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.4 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 0.4 GO:0044147 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.1 0.4 GO:0036343 psychomotor behavior(GO:0036343)
0.1 0.4 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1 0.2 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.1 0.8 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.8 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.3 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.3 GO:0018277 protein deamination(GO:0018277)
0.1 0.5 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.1 0.1 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.1 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.2 GO:0001834 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1 0.1 GO:0001711 endodermal cell fate commitment(GO:0001711) endodermal cell fate specification(GO:0001714)
0.1 0.2 GO:0099545 trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.1 0.2 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731)
0.1 0.2 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 0.1 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.1 0.3 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.1 0.3 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.8 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.1 GO:0097237 cellular response to toxic substance(GO:0097237)
0.1 0.1 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.2 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.1 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.0 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.2 GO:0036018 cellular response to erythropoietin(GO:0036018)
0.0 1.6 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.3 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.1 GO:0030822 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.0 GO:0060067 cervix development(GO:0060067)
0.0 0.1 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.1 GO:0038163 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163) regulation of male germ cell proliferation(GO:2000254)
0.0 0.1 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.2 GO:2001183 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.1 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.1 GO:0045006 DNA deamination(GO:0045006)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.1 GO:1990709 maintenance of synapse structure(GO:0099558) presynaptic active zone organization(GO:1990709)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.2 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.2 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 2.7 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0097052 L-kynurenine metabolic process(GO:0097052)
0.0 0.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.2 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.1 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773) lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0 0.1 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0042335 cuticle development(GO:0042335) hypophysis morphogenesis(GO:0048850)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0006173 dADP biosynthetic process(GO:0006173)
0.0 0.2 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.1 GO:0018032 protein amidation(GO:0018032)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.1 GO:1903217 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.2 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.1 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:1903824 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.4 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.0 GO:0090402 senescence-associated heterochromatin focus assembly(GO:0035986) oncogene-induced cell senescence(GO:0090402)
0.0 0.3 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:2000468 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:0009635 response to herbicide(GO:0009635) L-arginine import(GO:0043091) arginine import(GO:0090467)
0.0 0.1 GO:2000691 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.1 GO:0034093 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.3 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:2000006 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.1 GO:0038155 positive regulation of activation of Janus kinase activity(GO:0010536) interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.2 GO:0044557 relaxation of smooth muscle(GO:0044557)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.0 GO:0032606 regulation of type I interferon production(GO:0032479) type I interferon production(GO:0032606)
0.0 0.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:0072554 blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.1 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.1 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.2 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.1 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.3 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.0 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.0 0.0 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.0 0.0 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0035910 N-terminal peptidyl-lysine acetylation(GO:0018076) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.0 0.0 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.1 GO:0070458 establishment of blood-nerve barrier(GO:0008065) cellular detoxification of nitrogen compound(GO:0070458)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0002396 MHC protein complex assembly(GO:0002396) MHC class II protein complex assembly(GO:0002399)
0.0 0.1 GO:0042756 drinking behavior(GO:0042756)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 1.1 GO:2000257 regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.0 0.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.2 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0 0.1 GO:0002606 positive regulation of antigen processing and presentation(GO:0002579) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.4 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 0.0 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) renal water absorption(GO:0070295)
0.0 0.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.0 GO:1904796 regulation of core promoter binding(GO:1904796)
0.0 0.1 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0032596 protein transport into membrane raft(GO:0032596)
0.0 0.2 GO:0031033 myosin filament organization(GO:0031033)
0.0 0.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.2 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:1900122 positive regulation of receptor binding(GO:1900122)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.4 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 0.8 GO:0033269 internode region of axon(GO:0033269)
0.1 0.2 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.4 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0061200 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203) clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.2 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.3 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.1 GO:1990923 PET complex(GO:1990923)
0.0 0.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.1 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.3 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.0 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.6 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 0.5 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.1 0.1 GO:0035325 Toll-like receptor binding(GO:0035325)
0.1 0.4 GO:0055100 adiponectin binding(GO:0055100)
0.1 0.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.3 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.4 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.3 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.6 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.1 GO:0004145 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.5 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0032143 single thymine insertion binding(GO:0032143)
0.0 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.1 GO:0016297 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.0 GO:0004517 nitric-oxide synthase activity(GO:0004517) tetrahydrobiopterin binding(GO:0034617)
0.0 0.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 1.0 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.1 GO:0042007 interleukin-18 binding(GO:0042007)
0.0 0.2 GO:0042835 BRE binding(GO:0042835)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.1 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 1.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.4 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.1 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.1 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.0 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.2 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016) thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:1902271 D3 vitamins binding(GO:1902271)
0.0 0.1 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.0 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.1 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.1 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.0 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.0 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.0 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 0.1 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.2 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0008443 phosphofructokinase activity(GO:0008443)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.0 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.0 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.0 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.4 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.2 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.0 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease