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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for PPARA

Z-value: 0.63

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Transcription factors associated with PPARA

Gene Symbol Gene ID Gene Info
PPARA
ENSG00000186951.12 peroxisome proliferator activated receptor alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PPARAhg19_v2_chr22_+_46546494_46546525-0.237.7e-01Click!

Activity profile of PPARA motif

Sorted Z-values of PPARA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_21492331 0.61 ENST00000533984.1
ENST00000532213.2
AL161668.5
AL161668.5
chr22_+_22676808 0.59 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr12_-_124873357 0.50 ENST00000448614.1
NCOR2
nuclear receptor corepressor 2
chr10_-_10504285 0.35 ENST00000602311.1
RP11-271F18.4
RP11-271F18.4
chr12_-_6665200 0.28 ENST00000336604.4
ENST00000396840.2
ENST00000356896.4
IFFO1
intermediate filament family orphan 1
chr22_+_47158578 0.27 ENST00000355704.3
TBC1D22A
TBC1 domain family, member 22A
chr17_+_7533439 0.27 ENST00000441599.2
ENST00000380450.4
ENST00000416273.3
ENST00000575903.1
ENST00000576830.1
ENST00000571153.1
ENST00000575618.1
ENST00000576152.1
SHBG
sex hormone-binding globulin
chr18_-_43678241 0.27 ENST00000593152.2
ENST00000589252.1
ENST00000590665.1
ENST00000398752.6
ATP5A1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr10_+_81065975 0.27 ENST00000446377.2
ZMIZ1
zinc finger, MIZ-type containing 1
chrX_-_21776281 0.26 ENST00000379494.3
SMPX
small muscle protein, X-linked
chr17_-_42988004 0.26 ENST00000586125.1
ENST00000591880.1
GFAP
glial fibrillary acidic protein
chr15_+_75335604 0.25 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr3_-_117716418 0.23 ENST00000484092.1
RP11-384F7.2
RP11-384F7.2
chr22_-_39239987 0.22 ENST00000333039.2
NPTXR
neuronal pentraxin receptor
chr22_+_37959647 0.22 ENST00000415670.1
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr12_+_93963590 0.21 ENST00000340600.2
SOCS2
suppressor of cytokine signaling 2
chr4_-_40632140 0.21 ENST00000514782.1
RBM47
RNA binding motif protein 47
chr1_-_16532985 0.20 ENST00000441785.1
ENST00000449495.1
ARHGEF19
Rho guanine nucleotide exchange factor (GEF) 19
chr2_-_231860596 0.20 ENST00000441063.1
ENST00000434094.1
ENST00000418330.1
ENST00000457803.1
ENST00000414876.1
ENST00000446741.1
ENST00000426904.1
AC105344.2
SPATA3 antisense RNA 1 (head to head)
chr16_+_3704822 0.20 ENST00000414110.2
DNASE1
deoxyribonuclease I
chr20_+_43343886 0.19 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr19_-_51289374 0.19 ENST00000563228.1
CTD-2568A17.1
CTD-2568A17.1
chr17_-_30470154 0.19 ENST00000398832.2
AC090616.2
Uncharacterized protein
chr10_+_77056181 0.19 ENST00000526759.1
ENST00000533822.1
ZNF503-AS1
ZNF503 antisense RNA 1
chrX_+_18725758 0.19 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1
protein phosphatase, EF-hand calcium binding domain 1
chr5_+_133451254 0.19 ENST00000517851.1
ENST00000521639.1
ENST00000522375.1
ENST00000378560.4
ENST00000432532.2
ENST00000520958.1
ENST00000518915.1
ENST00000395023.1
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr3_+_188817891 0.19 ENST00000412373.1
TPRG1
tumor protein p63 regulated 1
chr17_-_1553346 0.19 ENST00000301336.6
RILP
Rab interacting lysosomal protein
chr6_-_149969871 0.19 ENST00000335643.8
ENST00000444282.1
KATNA1
katanin p60 (ATPase containing) subunit A 1
chr5_+_172332220 0.18 ENST00000518247.1
ENST00000326654.2
ERGIC1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr5_-_139930713 0.18 ENST00000602657.1
SRA1
steroid receptor RNA activator 1
chr14_+_75894391 0.18 ENST00000419727.2
JDP2
Jun dimerization protein 2
chr18_-_12377001 0.18 ENST00000590811.1
AFG3L2
AFG3-like AAA ATPase 2
chr8_+_94929273 0.17 ENST00000518573.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr22_+_51176624 0.17 ENST00000216139.5
ENST00000529621.1
ACR
acrosin
chr16_-_30997533 0.17 ENST00000602217.1
AC135048.1
Uncharacterized protein
chr19_-_36019123 0.17 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
SBSN
suprabasin
chr1_+_153600869 0.17 ENST00000292169.1
ENST00000368696.3
ENST00000436839.1
S100A1
S100 calcium binding protein A1
chr22_+_39101728 0.17 ENST00000216044.5
ENST00000484657.1
GTPBP1
GTP binding protein 1
chr1_+_45140400 0.17 ENST00000453711.1
C1orf228
chromosome 1 open reading frame 228
chr19_-_55881741 0.16 ENST00000264563.2
ENST00000590625.1
ENST00000585513.1
IL11
interleukin 11
chr6_+_30749649 0.16 ENST00000422944.1
HCG20
HLA complex group 20 (non-protein coding)
chr11_+_3877412 0.16 ENST00000527651.1
STIM1
stromal interaction molecule 1
chr22_+_32149927 0.16 ENST00000437411.1
ENST00000535622.1
ENST00000536766.1
ENST00000400242.3
ENST00000266091.3
ENST00000400249.2
ENST00000400246.1
ENST00000382105.2
DEPDC5
DEP domain containing 5
chr12_-_25348007 0.16 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
CASC1
cancer susceptibility candidate 1
chr11_+_77899842 0.16 ENST00000530267.1
USP35
ubiquitin specific peptidase 35
chr7_-_20826504 0.16 ENST00000418710.2
ENST00000361443.4
SP8
Sp8 transcription factor
chr6_-_149969829 0.16 ENST00000367411.2
KATNA1
katanin p60 (ATPase containing) subunit A 1
chr15_-_44487408 0.16 ENST00000402883.1
ENST00000417257.1
FRMD5
FERM domain containing 5
chr2_-_207023918 0.16 ENST00000455934.2
ENST00000449699.1
ENST00000454195.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr2_+_65663812 0.15 ENST00000606978.1
ENST00000377977.3
ENST00000536804.1
AC074391.1
AC074391.1
chr19_-_12912601 0.15 ENST00000334482.5
PRDX2
peroxiredoxin 2
chr19_-_49371711 0.15 ENST00000355496.5
ENST00000263265.6
PLEKHA4
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr17_+_74536115 0.15 ENST00000592014.1
PRCD
progressive rod-cone degeneration
chr9_-_35685452 0.15 ENST00000607559.1
TPM2
tropomyosin 2 (beta)
chr2_-_202316169 0.15 ENST00000430254.1
TRAK2
trafficking protein, kinesin binding 2
chr22_+_23237555 0.15 ENST00000390321.2
IGLC1
immunoglobulin lambda constant 1 (Mcg marker)
chr8_+_86376081 0.15 ENST00000285379.5
CA2
carbonic anhydrase II
chr20_+_19870167 0.15 ENST00000440354.2
RIN2
Ras and Rab interactor 2
chr6_-_34664612 0.15 ENST00000374023.3
ENST00000374026.3
C6orf106
chromosome 6 open reading frame 106
chr15_-_72767490 0.15 ENST00000565181.1
RP11-1007O24.3
RP11-1007O24.3
chr12_+_56511943 0.14 ENST00000257940.2
ENST00000552345.1
ENST00000551880.1
ENST00000546903.1
ENST00000551790.1
ZC3H10
ESYT1
zinc finger CCCH-type containing 10
extended synaptotagmin-like protein 1
chr17_+_7483761 0.14 ENST00000584180.1
CD68
CD68 molecule
chr16_+_69139467 0.14 ENST00000569188.1
HAS3
hyaluronan synthase 3
chr19_+_35629702 0.14 ENST00000351325.4
FXYD1
FXYD domain containing ion transport regulator 1
chr15_-_44486632 0.14 ENST00000484674.1
FRMD5
FERM domain containing 5
chr5_+_135383008 0.14 ENST00000508767.1
ENST00000604555.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr5_-_149682447 0.14 ENST00000328668.7
ARSI
arylsulfatase family, member I
chr17_+_7517264 0.14 ENST00000593717.1
ENST00000572182.1
ENST00000574539.1
ENST00000576728.1
ENST00000575314.1
ENST00000570547.1
ENST00000572262.1
ENST00000576478.1
AC007421.1
SHBG
AC007421.1
sex hormone-binding globulin
chr11_+_57308979 0.14 ENST00000457912.1
SMTNL1
smoothelin-like 1
chr17_+_40440481 0.14 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A
signal transducer and activator of transcription 5A
chr14_-_69444957 0.14 ENST00000556571.1
ENST00000553659.1
ENST00000555616.1
ACTN1
actinin, alpha 1
chr20_+_58179582 0.14 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr20_+_44462749 0.14 ENST00000372541.1
SNX21
sorting nexin family member 21
chr12_-_15865844 0.14 ENST00000543612.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr20_+_44486246 0.13 ENST00000255152.2
ENST00000454862.2
ZSWIM3
zinc finger, SWIM-type containing 3
chr2_-_207024134 0.13 ENST00000457011.1
ENST00000440274.1
ENST00000432169.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr8_-_42698292 0.13 ENST00000529779.1
THAP1
THAP domain containing, apoptosis associated protein 1
chr21_+_43823983 0.13 ENST00000291535.6
ENST00000450356.1
ENST00000319294.6
ENST00000398367.1
UBASH3A
ubiquitin associated and SH3 domain containing A
chr8_+_96037255 0.13 ENST00000286687.4
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr3_+_14444063 0.13 ENST00000454876.2
ENST00000360861.3
ENST00000416216.2
SLC6A6
solute carrier family 6 (neurotransmitter transporter), member 6
chr10_+_99185917 0.13 ENST00000334828.5
PGAM1
phosphoglycerate mutase 1 (brain)
chr9_+_21440440 0.13 ENST00000276927.1
IFNA1
interferon, alpha 1
chr6_+_13272904 0.13 ENST00000379335.3
ENST00000379329.1
PHACTR1
phosphatase and actin regulator 1
chr13_-_41635512 0.13 ENST00000405737.2
ELF1
E74-like factor 1 (ets domain transcription factor)
chr11_+_57365150 0.13 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr3_-_110612323 0.13 ENST00000383686.2
RP11-553A10.1
Uncharacterized protein
chr19_+_54466179 0.13 ENST00000270458.2
CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr8_+_97597148 0.13 ENST00000521590.1
SDC2
syndecan 2
chr15_-_78423567 0.13 ENST00000561190.1
ENST00000559645.1
ENST00000560618.1
ENST00000559054.1
CIB2
calcium and integrin binding family member 2
chr22_+_47158518 0.13 ENST00000337137.4
ENST00000380995.1
ENST00000407381.3
TBC1D22A
TBC1 domain family, member 22A
chr9_+_132388566 0.12 ENST00000372480.1
NTMT1
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chrX_+_44732757 0.12 ENST00000377967.4
ENST00000536777.1
ENST00000382899.4
ENST00000543216.1
KDM6A
lysine (K)-specific demethylase 6A
chr9_-_16705069 0.12 ENST00000471301.2
BNC2
basonuclin 2
chr6_+_36839616 0.12 ENST00000359359.2
ENST00000510325.2
C6orf89
chromosome 6 open reading frame 89
chr14_+_61654271 0.12 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH
protein kinase C, eta
chr14_+_73525265 0.12 ENST00000525161.1
RBM25
RNA binding motif protein 25
chr14_-_31889737 0.12 ENST00000382464.2
HEATR5A
HEAT repeat containing 5A
chr11_+_73498973 0.12 ENST00000537007.1
MRPL48
mitochondrial ribosomal protein L48
chr3_+_63638372 0.12 ENST00000496807.1
SNTN
sentan, cilia apical structure protein
chr12_+_109577202 0.12 ENST00000377848.3
ENST00000377854.5
ACACB
acetyl-CoA carboxylase beta
chr17_-_41174367 0.12 ENST00000587173.1
VAT1
vesicle amine transport 1
chr12_-_46121554 0.12 ENST00000609803.1
LINC00938
long intergenic non-protein coding RNA 938
chr11_-_45928830 0.12 ENST00000449465.1
C11orf94
chromosome 11 open reading frame 94
chr11_-_34379546 0.12 ENST00000435224.2
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chr7_+_35756186 0.12 ENST00000430518.1
AC018647.3
AC018647.3
chr8_-_107782463 0.12 ENST00000311955.3
ABRA
actin-binding Rho activating protein
chr17_-_70417365 0.12 ENST00000580948.1
LINC00511
long intergenic non-protein coding RNA 511
chr1_+_206858328 0.12 ENST00000367103.3
MAPKAPK2
mitogen-activated protein kinase-activated protein kinase 2
chr12_+_54378849 0.12 ENST00000515593.1
HOXC10
homeobox C10
chr4_-_65275162 0.12 ENST00000381210.3
ENST00000507440.1
TECRL
trans-2,3-enoyl-CoA reductase-like
chr1_-_33815486 0.12 ENST00000373418.3
PHC2
polyhomeotic homolog 2 (Drosophila)
chr6_-_2751146 0.11 ENST00000268446.5
ENST00000274643.7
MYLK4
myosin light chain kinase family, member 4
chr19_+_41699135 0.11 ENST00000542619.1
ENST00000600561.1
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr11_+_111957497 0.11 ENST00000375549.3
ENST00000528182.1
ENST00000528048.1
ENST00000528021.1
ENST00000526592.1
ENST00000525291.1
SDHD
succinate dehydrogenase complex, subunit D, integral membrane protein
chrX_-_152989798 0.11 ENST00000441714.1
ENST00000442093.1
ENST00000429550.1
ENST00000345046.6
BCAP31
B-cell receptor-associated protein 31
chr11_-_1783633 0.11 ENST00000367196.3
CTSD
cathepsin D
chr5_+_218356 0.11 ENST00000264932.6
ENST00000504309.1
ENST00000510361.1
SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr8_+_110656344 0.11 ENST00000499579.1
RP11-422N16.3
Uncharacterized protein
chr2_-_198364552 0.11 ENST00000439605.1
ENST00000418022.1
HSPD1
heat shock 60kDa protein 1 (chaperonin)
chr2_+_228678550 0.11 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr17_+_79670386 0.11 ENST00000333676.3
ENST00000571730.1
ENST00000541223.1
MRPL12
SLC25A10
SLC25A10
mitochondrial ribosomal protein L12
Mitochondrial dicarboxylate carrier; Uncharacterized protein; cDNA FLJ60124, highly similar to Mitochondrial dicarboxylate carrier
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr20_+_35807714 0.11 ENST00000373632.4
RPN2
ribophorin II
chr17_+_2699697 0.11 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
RAP1GAP2
RAP1 GTPase activating protein 2
chr3_-_110612059 0.11 ENST00000485473.1
RP11-553A10.1
Uncharacterized protein
chr6_+_31939608 0.11 ENST00000375331.2
ENST00000375333.2
STK19
serine/threonine kinase 19
chr3_-_124839648 0.11 ENST00000430155.2
SLC12A8
solute carrier family 12, member 8
chr7_-_105029812 0.11 ENST00000482897.1
SRPK2
SRSF protein kinase 2
chr22_+_21321447 0.11 ENST00000434714.1
AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr17_-_74722536 0.11 ENST00000585429.1
JMJD6
jumonji domain containing 6
chr12_-_96184913 0.11 ENST00000538383.1
NTN4
netrin 4
chr19_+_49109990 0.11 ENST00000321762.1
SPACA4
sperm acrosome associated 4
chr7_+_129007964 0.11 ENST00000460109.1
ENST00000474594.1
ENST00000446212.1
AHCYL2
adenosylhomocysteinase-like 2
chr12_-_109219937 0.11 ENST00000546697.1
SSH1
slingshot protein phosphatase 1
chr22_-_29784519 0.10 ENST00000357586.2
ENST00000356015.2
ENST00000432560.2
ENST00000317368.7
AP1B1
adaptor-related protein complex 1, beta 1 subunit
chr16_+_28874860 0.10 ENST00000545570.1
SH2B1
SH2B adaptor protein 1
chr12_-_16760195 0.10 ENST00000546281.1
ENST00000537757.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_-_103574024 0.10 ENST00000512756.1
ENST00000370096.3
ENST00000358392.2
ENST00000353414.4
COL11A1
collagen, type XI, alpha 1
chr1_+_199996733 0.10 ENST00000236914.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr11_+_57435441 0.10 ENST00000528177.1
ZDHHC5
zinc finger, DHHC-type containing 5
chr6_-_31107127 0.10 ENST00000259845.4
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr2_+_232457569 0.10 ENST00000313965.2
C2orf57
chromosome 2 open reading frame 57
chr8_-_145550337 0.10 ENST00000531896.1
DGAT1
diacylglycerol O-acyltransferase 1
chr19_+_10197463 0.10 ENST00000590378.1
ENST00000397881.3
C19orf66
chromosome 19 open reading frame 66
chr17_-_39216344 0.10 ENST00000391418.2
KRTAP2-3
keratin associated protein 2-3
chr6_+_149068464 0.10 ENST00000367463.4
UST
uronyl-2-sulfotransferase
chr20_+_45947246 0.10 ENST00000599904.1
AL031666.2
HCG2018772; Uncharacterized protein; cDNA FLJ31609 fis, clone NT2RI2002852
chr10_+_104178946 0.10 ENST00000432590.1
FBXL15
F-box and leucine-rich repeat protein 15
chrX_-_108868390 0.10 ENST00000372101.2
KCNE1L
KCNE1-like
chr6_-_36953833 0.10 ENST00000538808.1
ENST00000460219.1
ENST00000373616.5
ENST00000373627.5
MTCH1
mitochondrial carrier 1
chr11_+_77899920 0.10 ENST00000528910.1
ENST00000529308.1
USP35
ubiquitin specific peptidase 35
chr8_-_94928861 0.10 ENST00000607097.1
MIR378D2
microRNA 378d-2
chrX_+_47050798 0.10 ENST00000412206.1
ENST00000427561.1
UBA1
ubiquitin-like modifier activating enzyme 1
chr15_+_92397051 0.10 ENST00000424469.2
SLCO3A1
solute carrier organic anion transporter family, member 3A1
chr12_+_54426637 0.10 ENST00000312492.2
HOXC5
homeobox C5
chr1_-_150693318 0.10 ENST00000442853.1
ENST00000368995.4
ENST00000368993.2
ENST00000361824.2
ENST00000322343.7
HORMAD1
HORMA domain containing 1
chr1_-_19536744 0.10 ENST00000375267.2
ENST00000375217.2
ENST00000375226.2
ENST00000375254.3
UBR4
ubiquitin protein ligase E3 component n-recognin 4
chr1_-_229569834 0.10 ENST00000366684.3
ENST00000366683.2
ACTA1
actin, alpha 1, skeletal muscle
chr17_+_74536164 0.10 ENST00000586148.1
PRCD
progressive rod-cone degeneration
chr1_-_201140673 0.10 ENST00000367333.2
TMEM9
transmembrane protein 9
chr5_-_173217931 0.09 ENST00000522731.1
CTB-43E15.4
CTB-43E15.4
chr2_+_152214098 0.09 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr6_+_36973406 0.09 ENST00000274963.8
FGD2
FYVE, RhoGEF and PH domain containing 2
chr3_-_50340996 0.09 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
HYAL1
hyaluronoglucosaminidase 1
chr1_+_19923454 0.09 ENST00000602662.1
ENST00000602293.1
ENST00000322753.6
MINOS1-NBL1
MINOS1
MINOS1-NBL1 readthrough
mitochondrial inner membrane organizing system 1
chr1_+_169077133 0.09 ENST00000494797.1
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr1_-_35325318 0.09 ENST00000423898.1
ENST00000456842.1
SMIM12
small integral membrane protein 12
chr17_-_79900255 0.09 ENST00000330655.3
ENST00000582198.1
MYADML2
PYCR1
myeloid-associated differentiation marker-like 2
pyrroline-5-carboxylate reductase 1
chr17_+_13972807 0.09 ENST00000429152.2
ENST00000261643.3
ENST00000536205.1
ENST00000537334.1
COX10
cytochrome c oxidase assembly homolog 10 (yeast)
chr9_-_16728161 0.09 ENST00000603713.1
ENST00000603313.1
BNC2
basonuclin 2
chr14_-_23395623 0.09 ENST00000556043.1
PRMT5
protein arginine methyltransferase 5
chr12_-_48214345 0.09 ENST00000433685.1
ENST00000447463.1
ENST00000427332.2
HDAC7
histone deacetylase 7
chr5_+_179125907 0.09 ENST00000247461.4
ENST00000452673.2
ENST00000502498.1
ENST00000507307.1
ENST00000513246.1
ENST00000502673.1
ENST00000506654.1
ENST00000512607.2
ENST00000510810.1
CANX
calnexin
chr14_+_75894714 0.09 ENST00000559060.1
JDP2
Jun dimerization protein 2
chr1_-_154164534 0.09 ENST00000271850.7
ENST00000368530.2
TPM3
tropomyosin 3
chr5_+_129240151 0.09 ENST00000305031.4
CHSY3
chondroitin sulfate synthase 3
chr17_+_19281787 0.09 ENST00000482850.1
MAPK7
mitogen-activated protein kinase 7
chr2_+_134877740 0.09 ENST00000409645.1
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr11_-_66103932 0.09 ENST00000311320.4
RIN1
Ras and Rab interactor 1
chr8_-_53626974 0.09 ENST00000435644.2
ENST00000518710.1
ENST00000025008.5
ENST00000517963.1
RB1CC1
RB1-inducible coiled-coil 1
chr15_+_67418047 0.09 ENST00000540846.2
SMAD3
SMAD family member 3
chr17_+_73975292 0.09 ENST00000397640.1
ENST00000416485.1
ENST00000588202.1
ENST00000590676.1
ENST00000586891.1
TEN1
TEN1 CST complex subunit
chr17_-_74722672 0.09 ENST00000397625.4
ENST00000445478.2
JMJD6
jumonji domain containing 6
chr20_+_3776371 0.09 ENST00000245960.5
CDC25B
cell division cycle 25B
chr1_-_157014865 0.09 ENST00000361409.2
ARHGEF11
Rho guanine nucleotide exchange factor (GEF) 11
chr22_+_30792980 0.09 ENST00000403484.1
ENST00000405717.3
ENST00000402592.3
SEC14L2
SEC14-like 2 (S. cerevisiae)
chr12_+_6833323 0.09 ENST00000544725.1
COPS7A
COP9 signalosome subunit 7A
chr16_-_74734742 0.09 ENST00000308807.7
ENST00000573267.1
MLKL
mixed lineage kinase domain-like
chr7_+_45613958 0.09 ENST00000297323.7
ADCY1
adenylate cyclase 1 (brain)
chr3_-_141747950 0.09 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr22_-_38699003 0.09 ENST00000451964.1
CSNK1E
casein kinase 1, epsilon
chrX_+_70521584 0.09 ENST00000373829.3
ENST00000538820.1
ITGB1BP2
integrin beta 1 binding protein (melusin) 2
chr4_+_108852697 0.09 ENST00000508453.1
CYP2U1
cytochrome P450, family 2, subfamily U, polypeptide 1
chr12_+_6976687 0.09 ENST00000396705.5
TPI1
triosephosphate isomerase 1
chr1_+_155179012 0.09 ENST00000609421.1
MTX1
metaxin 1
chr1_-_150849047 0.09 ENST00000354396.2
ENST00000505755.1
ARNT
aryl hydrocarbon receptor nuclear translocator
chr10_-_127464390 0.09 ENST00000368808.3
MMP21
matrix metallopeptidase 21
chr5_+_154181816 0.09 ENST00000518677.1
LARP1
La ribonucleoprotein domain family, member 1
chr15_+_65337708 0.09 ENST00000334287.2
SLC51B
solute carrier family 51, beta subunit
chr9_+_115983808 0.09 ENST00000374210.6
ENST00000374212.4
SLC31A1
solute carrier family 31 (copper transporter), member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of PPARA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 0.2 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.1 GO:0045041 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.1 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.2 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
0.0 0.1 GO:0035568 N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138) regulation of homologous chromosome segregation(GO:0060629)
0.0 0.3 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0002339 B cell selection(GO:0002339) B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.1 GO:0045362 interleukin-1 biosynthetic process(GO:0042222) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.1 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0 0.2 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.1 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.2 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.2 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.2 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:0071423 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.2 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0045208 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.3 GO:1903278 regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278)
0.0 0.1 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.1 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.0 0.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0042746 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.0 0.1 GO:2000909 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.0 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.0 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.1 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.0 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.0 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.4 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.0 GO:2000374 regulation of oxygen metabolic process(GO:2000374)
0.0 0.1 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.2 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.2 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.2 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.1 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.0 GO:0021503 neural fold bending(GO:0021503)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.1 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.2 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.1 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.1 GO:0043129 surfactant homeostasis(GO:0043129)
0.0 0.0 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.0 0.1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.2 GO:0036117 hyaluranon cable(GO:0036117)
0.1 0.3 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.2 GO:0005745 m-AAA complex(GO:0005745)
0.1 0.4 GO:0070470 plasma membrane respiratory chain complex I(GO:0045272) plasma membrane respiratory chain(GO:0070470)
0.0 0.3 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.0 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.0 0.0 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.2 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.3 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.4 GO:0005497 androgen binding(GO:0005497)
0.0 0.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.2 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.2 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.1 GO:1990175 EH domain binding(GO:1990175)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.0 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.0 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.0 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.0 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.0 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.0 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.0 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.0 GO:0000035 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators