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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for PTF1A

Z-value: 1.43

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Transcription factors associated with PTF1A

Gene Symbol Gene ID Gene Info
PTF1A
ENSG00000168267.5 pancreas associated transcription factor 1a

Activity profile of PTF1A motif

Sorted Z-values of PTF1A motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_113344811 1.65 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_+_113344582 1.44 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_+_113344755 1.37 ENST00000550883.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr1_+_23037323 1.33 ENST00000544305.1
ENST00000374630.3
ENST00000400191.3
ENST00000374632.3
EPHB2
EPH receptor B2
chr4_-_129491686 1.29 ENST00000514265.1
RP11-184M15.1
RP11-184M15.1
chr2_-_106777040 1.13 ENST00000444193.1
ENST00000416298.1
UXS1
UDP-glucuronate decarboxylase 1
chr3_-_172241250 1.12 ENST00000420541.2
ENST00000241261.2
TNFSF10
tumor necrosis factor (ligand) superfamily, member 10
chr1_+_150480551 1.07 ENST00000369049.4
ENST00000369047.4
ECM1
extracellular matrix protein 1
chr12_+_2912363 1.03 ENST00000544366.1
FKBP4
FK506 binding protein 4, 59kDa
chr1_+_150480576 0.87 ENST00000346569.6
ECM1
extracellular matrix protein 1
chr10_-_10504285 0.77 ENST00000602311.1
RP11-271F18.4
RP11-271F18.4
chr19_+_29493486 0.73 ENST00000589821.1
CTD-2081K17.2
CTD-2081K17.2
chr15_+_41099919 0.65 ENST00000561617.1
ZFYVE19
zinc finger, FYVE domain containing 19
chr18_+_33877654 0.64 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
FHOD3
formin homology 2 domain containing 3
chr19_+_11670245 0.61 ENST00000585493.1
ZNF627
zinc finger protein 627
chr15_+_41099788 0.61 ENST00000299173.10
ENST00000566407.1
ZFYVE19
zinc finger, FYVE domain containing 19
chr2_-_1748214 0.60 ENST00000433670.1
ENST00000425171.1
ENST00000252804.4
PXDN
peroxidasin homolog (Drosophila)
chr6_-_46620522 0.58 ENST00000275016.2
CYP39A1
cytochrome P450, family 39, subfamily A, polypeptide 1
chr14_+_67656110 0.57 ENST00000524532.1
ENST00000530728.1
FAM71D
family with sequence similarity 71, member D
chr17_+_67498295 0.56 ENST00000589295.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr11_-_61735103 0.54 ENST00000529191.1
ENST00000529631.1
ENST00000530019.1
ENST00000529548.1
ENST00000273550.7
FTH1
ferritin, heavy polypeptide 1
chr8_+_32405728 0.52 ENST00000523079.1
ENST00000338921.4
ENST00000356819.4
ENST00000287845.5
ENST00000341377.5
NRG1
neuregulin 1
chr5_-_173217931 0.50 ENST00000522731.1
CTB-43E15.4
CTB-43E15.4
chr2_-_239140011 0.50 ENST00000409376.1
ENST00000409070.1
ENST00000409942.1
AC016757.3
Protein LOC151174
chr12_+_75784850 0.49 ENST00000550916.1
ENST00000435775.1
ENST00000378689.2
ENST00000378692.3
ENST00000320460.4
ENST00000547164.1
GLIPR1L2
GLI pathogenesis-related 1 like 2
chr12_+_112451222 0.49 ENST00000552052.1
ERP29
endoplasmic reticulum protein 29
chr1_-_205649580 0.48 ENST00000367145.3
SLC45A3
solute carrier family 45, member 3
chr20_+_42544782 0.48 ENST00000423191.2
ENST00000372999.1
TOX2
TOX high mobility group box family member 2
chr8_+_32405785 0.45 ENST00000287842.3
NRG1
neuregulin 1
chr6_-_134499037 0.44 ENST00000528577.1
SGK1
serum/glucocorticoid regulated kinase 1
chr3_+_101546827 0.44 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr19_-_44258733 0.43 ENST00000597586.1
ENST00000596714.1
SMG9
SMG9 nonsense mediated mRNA decay factor
chr17_-_61778528 0.42 ENST00000584645.1
LIMD2
LIM domain containing 2
chr16_+_2802623 0.42 ENST00000576924.1
ENST00000575009.1
ENST00000576415.1
ENST00000571378.1
SRRM2
serine/arginine repetitive matrix 2
chr19_+_54496132 0.41 ENST00000346968.2
CACNG6
calcium channel, voltage-dependent, gamma subunit 6
chr1_-_9129598 0.41 ENST00000535586.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr11_-_45687128 0.40 ENST00000308064.2
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr17_+_79859985 0.39 ENST00000333383.7
NPB
neuropeptide B
chr2_-_196933536 0.38 ENST00000312428.6
ENST00000410072.1
DNAH7
dynein, axonemal, heavy chain 7
chr4_+_81951957 0.36 ENST00000282701.2
BMP3
bone morphogenetic protein 3
chr3_-_88108212 0.36 ENST00000482016.1
CGGBP1
CGG triplet repeat binding protein 1
chr2_-_27435125 0.36 ENST00000414408.1
ENST00000310574.3
SLC5A6
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr19_+_29493456 0.36 ENST00000591143.1
ENST00000592653.1
CTD-2081K17.2
CTD-2081K17.2
chrX_+_15808569 0.35 ENST00000380308.3
ENST00000307771.7
ZRSR2
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
chr19_-_17014408 0.34 ENST00000594249.1
CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chrX_+_48242863 0.34 ENST00000376886.2
ENST00000375517.3
SSX4
synovial sarcoma, X breakpoint 4
chr14_-_35099315 0.34 ENST00000396526.3
ENST00000396534.3
ENST00000355110.5
ENST00000557265.1
SNX6
sorting nexin 6
chr15_+_68924327 0.34 ENST00000543950.1
CORO2B
coronin, actin binding protein, 2B
chr8_-_135725205 0.33 ENST00000523399.1
ENST00000377838.3
ZFAT
zinc finger and AT hook domain containing
chr1_+_178694300 0.32 ENST00000367635.3
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr4_-_123843597 0.32 ENST00000510735.1
ENST00000304430.5
NUDT6
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr15_+_91446961 0.32 ENST00000559965.1
MAN2A2
mannosidase, alpha, class 2A, member 2
chr12_+_31079652 0.32 ENST00000546076.1
ENST00000535215.1
ENST00000544427.1
ENST00000261177.9
TSPAN11
tetraspanin 11
chr8_-_145641864 0.32 ENST00000276833.5
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr21_+_44073916 0.32 ENST00000349112.3
ENST00000398224.3
PDE9A
phosphodiesterase 9A
chr17_+_68047418 0.31 ENST00000586373.1
ENST00000588782.1
LINC01028
long intergenic non-protein coding RNA 1028
chr22_-_50523760 0.30 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr3_-_12883026 0.29 ENST00000396953.2
ENST00000457131.1
ENST00000435983.1
ENST00000273223.6
ENST00000396957.1
ENST00000429711.2
RPL32
ribosomal protein L32
chr21_+_44073860 0.29 ENST00000335512.4
ENST00000539837.1
ENST00000291539.6
ENST00000380328.2
ENST00000398232.3
ENST00000398234.3
ENST00000398236.3
ENST00000328862.6
ENST00000335440.6
ENST00000398225.3
ENST00000398229.3
ENST00000398227.3
PDE9A
phosphodiesterase 9A
chr15_+_84841242 0.29 ENST00000558195.1
RP11-182J1.16
ubiquitin-conjugating enzyme E2Q family member 2-like
chr11_+_71276609 0.29 ENST00000398531.1
ENST00000376536.4
KRTAP5-10
keratin associated protein 5-10
chr11_-_64052111 0.29 ENST00000394532.3
ENST00000394531.3
ENST00000309032.3
BAD
BCL2-associated agonist of cell death
chr16_+_2802316 0.28 ENST00000301740.8
SRRM2
serine/arginine repetitive matrix 2
chr2_-_228497888 0.28 ENST00000264387.4
ENST00000409066.1
C2orf83
chromosome 2 open reading frame 83
chr17_-_33415837 0.28 ENST00000414419.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr17_-_73892992 0.27 ENST00000540128.1
ENST00000269383.3
TRIM65
tripartite motif containing 65
chr19_+_45254529 0.27 ENST00000444487.1
BCL3
B-cell CLL/lymphoma 3
chr10_+_43572475 0.27 ENST00000355710.3
ENST00000498820.1
ENST00000340058.5
RET
ret proto-oncogene
chr2_-_86422523 0.27 ENST00000442664.2
ENST00000409051.2
ENST00000449247.2
IMMT
inner membrane protein, mitochondrial
chr1_+_178694362 0.26 ENST00000367634.2
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr6_-_2962331 0.26 ENST00000380524.1
SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr15_+_81225699 0.26 ENST00000560027.1
KIAA1199
KIAA1199
chr6_-_62996066 0.25 ENST00000281156.4
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr1_+_157963391 0.25 ENST00000359209.6
ENST00000416935.2
KIRREL
kin of IRRE like (Drosophila)
chr8_-_145642203 0.24 ENST00000526658.1
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr1_+_40204538 0.24 ENST00000324379.5
ENST00000356511.2
ENST00000497370.1
ENST00000470213.1
ENST00000372835.5
ENST00000372830.1
PPIE
peptidylprolyl isomerase E (cyclophilin E)
chr19_+_54495542 0.24 ENST00000252729.2
ENST00000352529.1
CACNG6
calcium channel, voltage-dependent, gamma subunit 6
chr10_-_28571015 0.23 ENST00000375719.3
ENST00000375732.1
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr1_-_9129895 0.23 ENST00000473209.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr8_-_22089533 0.21 ENST00000321613.3
PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr2_+_173600565 0.21 ENST00000397081.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr14_-_35099377 0.21 ENST00000362031.4
SNX6
sorting nexin 6
chr19_-_48389651 0.20 ENST00000222002.3
SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr17_+_12692774 0.20 ENST00000379672.5
ENST00000340825.3
ARHGAP44
Rho GTPase activating protein 44
chr12_+_112451120 0.20 ENST00000261735.3
ENST00000455836.1
ERP29
endoplasmic reticulum protein 29
chr2_+_173600514 0.20 ENST00000264111.6
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr8_-_110660975 0.19 ENST00000528045.1
SYBU
syntabulin (syntaxin-interacting)
chr4_-_87278857 0.18 ENST00000509464.1
ENST00000511167.1
MAPK10
mitogen-activated protein kinase 10
chr2_+_85922491 0.18 ENST00000526018.1
GNLY
granulysin
chr11_+_64052266 0.18 ENST00000539851.1
GPR137
G protein-coupled receptor 137
chr2_-_71454185 0.18 ENST00000244221.8
PAIP2B
poly(A) binding protein interacting protein 2B
chr2_+_120187465 0.18 ENST00000409826.1
ENST00000417645.1
TMEM37
transmembrane protein 37
chr12_+_109826524 0.17 ENST00000431443.2
MYO1H
myosin IH
chr1_+_151682909 0.17 ENST00000326413.3
ENST00000442233.2
RIIAD1
AL589765.1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
Uncharacterized protein; cDNA FLJ36032 fis, clone TESTI2017069
chr20_-_48732472 0.17 ENST00000340309.3
ENST00000415862.2
ENST00000371677.3
ENST00000420027.2
UBE2V1
ubiquitin-conjugating enzyme E2 variant 1
chr8_-_22089845 0.17 ENST00000454243.2
PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr1_-_45956868 0.17 ENST00000451835.2
TESK2
testis-specific kinase 2
chr3_+_35681081 0.16 ENST00000428373.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr19_+_6464502 0.16 ENST00000308243.7
CRB3
crumbs homolog 3 (Drosophila)
chr17_+_67498538 0.16 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr4_-_89744365 0.16 ENST00000513837.1
ENST00000503556.1
FAM13A
family with sequence similarity 13, member A
chr2_+_3393453 0.15 ENST00000441983.1
TRAPPC12
trafficking protein particle complex 12
chrX_-_134305322 0.15 ENST00000276241.6
ENST00000344129.2
CXorf48
cancer/testis antigen 55
chr16_-_65155833 0.15 ENST00000566827.1
ENST00000394156.3
ENST00000562998.1
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr12_+_12966250 0.15 ENST00000352940.4
ENST00000358007.3
ENST00000544400.1
DDX47
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr22_-_17640110 0.15 ENST00000399852.3
ENST00000336737.4
CECR5
cat eye syndrome chromosome region, candidate 5
chr11_+_64052454 0.14 ENST00000539833.1
GPR137
G protein-coupled receptor 137
chr2_-_27434611 0.14 ENST00000408041.1
SLC5A6
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr14_-_38028689 0.14 ENST00000553425.1
RP11-356O9.2
RP11-356O9.2
chr11_+_8704748 0.14 ENST00000526562.1
ENST00000525981.1
RPL27A
ribosomal protein L27a
chr10_+_43633914 0.14 ENST00000374466.3
ENST00000374464.1
CSGALNACT2
chondroitin sulfate N-acetylgalactosaminyltransferase 2
chr6_-_24877490 0.14 ENST00000540914.1
ENST00000378023.4
FAM65B
family with sequence similarity 65, member B
chr5_+_125800836 0.13 ENST00000511134.1
GRAMD3
GRAM domain containing 3
chrX_-_13956497 0.13 ENST00000398361.3
GPM6B
glycoprotein M6B
chr1_-_45956800 0.12 ENST00000538496.1
TESK2
testis-specific kinase 2
chr19_-_1168936 0.12 ENST00000587655.1
SBNO2
strawberry notch homolog 2 (Drosophila)
chr7_+_6714599 0.12 ENST00000328239.7
ENST00000542006.1
AC073343.1
Uncharacterized protein
chr4_-_89744314 0.12 ENST00000508369.1
FAM13A
family with sequence similarity 13, member A
chr17_+_6918064 0.12 ENST00000546760.1
ENST00000552402.1
C17orf49
chromosome 17 open reading frame 49
chr17_-_33416231 0.12 ENST00000584655.1
ENST00000447669.2
ENST00000315249.7
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr3_-_193272874 0.12 ENST00000342695.4
ATP13A4
ATPase type 13A4
chr3_+_40518599 0.12 ENST00000314686.5
ENST00000447116.2
ENST00000429348.2
ENST00000456778.1
ZNF619
zinc finger protein 619
chr1_-_33647267 0.11 ENST00000291416.5
TRIM62
tripartite motif containing 62
chr1_+_171454639 0.11 ENST00000392078.3
ENST00000426496.2
PRRC2C
proline-rich coiled-coil 2C
chr6_-_127780510 0.10 ENST00000487331.2
ENST00000483725.3
KIAA0408
KIAA0408
chr8_+_97773457 0.10 ENST00000521142.1
CPQ
carboxypeptidase Q
chr5_+_132149017 0.10 ENST00000378693.2
SOWAHA
sosondowah ankyrin repeat domain family member A
chr5_-_39425290 0.10 ENST00000545653.1
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr14_+_70346125 0.10 ENST00000361956.3
ENST00000381280.4
SMOC1
SPARC related modular calcium binding 1
chr18_-_53177984 0.10 ENST00000543082.1
TCF4
transcription factor 4
chr12_+_53689309 0.10 ENST00000351500.3
ENST00000550846.1
ENST00000334478.4
ENST00000549759.1
PFDN5
prefoldin subunit 5
chr11_+_64052294 0.10 ENST00000536667.1
GPR137
G protein-coupled receptor 137
chr22_-_50051151 0.10 ENST00000400023.1
ENST00000444628.1
C22orf34
chromosome 22 open reading frame 34
chr17_-_42143963 0.09 ENST00000585388.1
ENST00000293406.3
LSM12
LSM12 homolog (S. cerevisiae)
chr4_+_40198527 0.09 ENST00000381799.5
RHOH
ras homolog family member H
chr4_-_89744457 0.09 ENST00000395002.2
FAM13A
family with sequence similarity 13, member A
chr16_+_5121814 0.08 ENST00000262374.5
ENST00000586840.1
ALG1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr13_-_31736132 0.08 ENST00000429785.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr1_-_40782347 0.08 ENST00000417105.1
COL9A2
collagen, type IX, alpha 2
chr17_+_67498396 0.08 ENST00000588110.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr6_-_24489842 0.08 ENST00000230036.1
GPLD1
glycosylphosphatidylinositol specific phospholipase D1
chr8_+_11351876 0.08 ENST00000529894.1
BLK
B lymphoid tyrosine kinase
chr4_-_175750364 0.07 ENST00000340217.5
ENST00000274093.3
GLRA3
glycine receptor, alpha 3
chr6_-_41715128 0.07 ENST00000356667.4
ENST00000373025.3
ENST00000425343.2
PGC
progastricsin (pepsinogen C)
chr1_+_100503643 0.06 ENST00000370152.3
HIAT1
hippocampus abundant transcript 1
chr3_-_169587621 0.06 ENST00000523069.1
ENST00000316428.5
ENST00000264676.5
LRRC31
leucine rich repeat containing 31
chr5_+_173315283 0.06 ENST00000265085.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr8_+_11351494 0.06 ENST00000259089.4
BLK
B lymphoid tyrosine kinase
chr2_+_27435179 0.05 ENST00000606999.1
ENST00000405489.3
ATRAID
all-trans retinoic acid-induced differentiation factor
chr4_-_5990166 0.05 ENST00000324058.5
C4orf50
chromosome 4 open reading frame 50
chr5_-_39425068 0.05 ENST00000515700.1
ENST00000339788.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr21_+_39668831 0.05 ENST00000419868.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr17_-_3461092 0.05 ENST00000301365.4
ENST00000572519.1
TRPV3
transient receptor potential cation channel, subfamily V, member 3
chr19_-_46526304 0.05 ENST00000008938.4
PGLYRP1
peptidoglycan recognition protein 1
chr2_-_237416181 0.05 ENST00000409907.3
IQCA1
IQ motif containing with AAA domain 1
chr2_-_237416071 0.05 ENST00000309507.5
ENST00000431676.2
IQCA1
IQ motif containing with AAA domain 1
chr5_-_39425222 0.05 ENST00000320816.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr17_-_36499693 0.04 ENST00000342292.4
GPR179
G protein-coupled receptor 179
chr11_+_64052692 0.04 ENST00000377702.4
GPR137
G protein-coupled receptor 137
chr13_-_111522162 0.04 ENST00000538077.1
LINC00346
long intergenic non-protein coding RNA 346
chr4_+_184826418 0.04 ENST00000308497.4
ENST00000438269.1
STOX2
storkhead box 2
chr3_+_51663407 0.04 ENST00000432863.1
ENST00000296477.3
RAD54L2
RAD54-like 2 (S. cerevisiae)
chr1_+_178694408 0.03 ENST00000324778.5
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr5_-_16916624 0.03 ENST00000513882.1
MYO10
myosin X
chr11_-_1629693 0.03 ENST00000399685.1
KRTAP5-3
keratin associated protein 5-3
chr13_-_79979952 0.03 ENST00000438724.1
RBM26
RNA binding motif protein 26
chr9_-_19033185 0.03 ENST00000380534.4
FAM154A
family with sequence similarity 154, member A
chr9_-_116061145 0.02 ENST00000416588.2
RNF183
ring finger protein 183
chr3_-_122712079 0.02 ENST00000393583.2
SEMA5B
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
chr10_-_74856608 0.02 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
P4HA1
prolyl 4-hydroxylase, alpha polypeptide I
chr16_-_15950868 0.02 ENST00000396324.3
ENST00000452625.2
ENST00000576790.2
ENST00000300036.5
MYH11
myosin, heavy chain 11, smooth muscle
chr13_+_113812956 0.02 ENST00000375547.2
ENST00000342783.4
PROZ
protein Z, vitamin K-dependent plasma glycoprotein
chr4_-_82393009 0.02 ENST00000436139.2
RASGEF1B
RasGEF domain family, member 1B
chr16_-_2004683 0.02 ENST00000268661.7
RPL3L
ribosomal protein L3-like
chr19_-_11039261 0.02 ENST00000590329.1
ENST00000587943.1
ENST00000585858.1
ENST00000586748.1
ENST00000586575.1
ENST00000253031.2
YIPF2
Yip1 domain family, member 2
chr7_-_72993033 0.01 ENST00000305632.5
TBL2
transducin (beta)-like 2
chr11_+_207477 0.01 ENST00000526104.1
RIC8A
RIC8 guanine nucleotide exchange factor A
chr7_-_99097863 0.01 ENST00000426306.2
ENST00000337673.6
ZNF394
zinc finger protein 394
chr20_+_30697298 0.01 ENST00000398022.2
TM9SF4
transmembrane 9 superfamily protein member 4
chr2_-_95831158 0.01 ENST00000447814.1
ZNF514
zinc finger protein 514
chr13_-_79979919 0.01 ENST00000267229.7
RBM26
RNA binding motif protein 26
chr1_-_9129735 0.01 ENST00000377424.4
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr22_+_24999114 0.01 ENST00000412658.1
ENST00000445029.1
ENST00000419133.1
ENST00000400382.1
ENST00000438643.2
ENST00000452551.1
ENST00000400383.1
ENST00000412898.1
ENST00000400380.1
ENST00000455483.1
ENST00000430289.1
GGT1
gamma-glutamyltransferase 1
chr7_+_150688166 0.01 ENST00000461406.1
NOS3
nitric oxide synthase 3 (endothelial cell)
chr9_-_138853156 0.00 ENST00000371756.3
UBAC1
UBA domain containing 1
chr1_-_45956822 0.00 ENST00000372086.3
ENST00000341771.6
TESK2
testis-specific kinase 2
chr9_+_4985228 0.00 ENST00000381652.3
JAK2
Janus kinase 2
chr12_-_75603643 0.00 ENST00000549446.1
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr8_+_97773202 0.00 ENST00000519484.1
CPQ
carboxypeptidase Q

Network of associatons between targets according to the STRING database.

First level regulatory network of PTF1A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.4 1.1 GO:0033319 UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320)
0.2 1.3 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.2 0.8 GO:0072709 cellular response to sorbitol(GO:0072709)
0.2 0.8 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 0.7 GO:0043335 protein unfolding(GO:0043335)
0.1 0.5 GO:0015770 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 0.6 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 1.0 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.3 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.3 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1 0.6 GO:1990539 fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.1 0.5 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.1 1.9 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 0.6 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 0.5 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 0.4 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.2 GO:0002818 intracellular defense response(GO:0002818)
0.1 0.3 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.3 GO:0097021 positive regulation of metanephric glomerulus development(GO:0072300) lymphocyte migration into lymphoid organs(GO:0097021)
0.0 4.5 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.3 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.2 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 1.0 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.8 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0 0.1 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 0.6 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.2 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.1 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.4 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.1 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.3 GO:0001654 eye development(GO:0001654)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.3 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.0 GO:0002325 natural killer cell differentiation involved in immune response(GO:0002325) regulation of natural killer cell differentiation involved in immune response(GO:0032826) regulation of cytolysis in other organism(GO:0051710)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.4 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.3 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.1 0.4 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.1 1.9 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.4 GO:0036156 inner dynein arm(GO:0036156)
0.1 0.3 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.5 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 0.2 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 0.4 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.0 0.9 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.7 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 1.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0048040 UDP-glucuronate decarboxylase activity(GO:0048040)
0.4 4.5 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.3 1.9 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.3 1.0 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 1.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.5 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.6 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 1.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.3 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.3 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.1 0.5 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 0.6 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.5 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.4 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.5 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.7 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 1.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.7 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 1.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.6 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.6 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.0 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0 0.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.8 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 1.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.8 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects