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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for RAD21_SMC3

Z-value: 0.83

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Transcription factors associated with RAD21_SMC3

Gene Symbol Gene ID Gene Info
RAD21
ENSG00000164754.8 RAD21 cohesin complex component
SMC3
ENSG00000108055.9 structural maintenance of chromosomes 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RAD21hg19_v2_chr8_-_117886732_117886767-0.584.2e-01Click!
SMC3hg19_v2_chr10_+_112327425_112327516-0.277.3e-01Click!

Activity profile of RAD21_SMC3 motif

Sorted Z-values of RAD21_SMC3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_302918 0.59 ENST00000599994.1
AC187652.1
Protein LOC100996433
chr2_+_27309605 0.53 ENST00000260599.6
ENST00000260598.5
ENST00000429697.1
KHK
ketohexokinase (fructokinase)
chr16_+_29127282 0.51 ENST00000562902.1
RP11-426C22.5
RP11-426C22.5
chr11_-_8285405 0.45 ENST00000335790.3
ENST00000534484.1
LMO1
LIM domain only 1 (rhombotin 1)
chr18_-_26941900 0.45 ENST00000577674.1
CTD-2515C13.2
CTD-2515C13.2
chr19_-_36001386 0.43 ENST00000461300.1
DMKN
dermokine
chr18_+_43753500 0.38 ENST00000587591.1
ENST00000588730.1
C18orf25
chromosome 18 open reading frame 25
chr22_+_22723969 0.37 ENST00000390295.2
IGLV7-46
immunoglobulin lambda variable 7-46 (gene/pseudogene)
chr20_+_36531499 0.37 ENST00000373458.3
ENST00000373461.4
ENST00000373459.4
VSTM2L
V-set and transmembrane domain containing 2 like
chr19_+_41313017 0.36 ENST00000595621.1
ENST00000595051.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr2_+_20866424 0.35 ENST00000272224.3
GDF7
growth differentiation factor 7
chr17_-_36891830 0.35 ENST00000578487.1
PCGF2
polycomb group ring finger 2
chr16_+_84002234 0.34 ENST00000305202.4
NECAB2
N-terminal EF-hand calcium binding protein 2
chr19_+_4791722 0.33 ENST00000269856.3
FEM1A
fem-1 homolog a (C. elegans)
chr2_-_154335300 0.33 ENST00000325926.3
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr1_-_146989697 0.33 ENST00000437831.1
LINC00624
long intergenic non-protein coding RNA 624
chr12_+_58176525 0.32 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
TSFM
Ts translation elongation factor, mitochondrial
chr4_-_41884620 0.32 ENST00000504870.1
LINC00682
long intergenic non-protein coding RNA 682
chr2_+_11273179 0.31 ENST00000381585.3
ENST00000405022.3
C2orf50
chromosome 2 open reading frame 50
chrX_-_27417088 0.31 ENST00000608735.1
ENST00000422048.1
RP11-268G12.1
RP11-268G12.1
chr17_+_73629500 0.30 ENST00000375215.3
SMIM5
small integral membrane protein 5
chr5_-_125930929 0.30 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr11_-_117102768 0.30 ENST00000532301.1
PCSK7
proprotein convertase subtilisin/kexin type 7
chr11_+_118826999 0.30 ENST00000264031.2
UPK2
uroplakin 2
chr12_+_82752283 0.30 ENST00000548200.1
METTL25
methyltransferase like 25
chr11_+_73675873 0.30 ENST00000537753.1
ENST00000542350.1
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr9_-_139258159 0.30 ENST00000371739.3
DNLZ
DNL-type zinc finger
chr11_-_117103208 0.29 ENST00000320934.3
ENST00000530269.1
PCSK7
proprotein convertase subtilisin/kexin type 7
chr17_+_7591747 0.28 ENST00000534050.1
WRAP53
WD repeat containing, antisense to TP53
chr16_+_69345243 0.28 ENST00000254950.11
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr5_-_139726181 0.27 ENST00000507104.1
ENST00000230990.6
HBEGF
heparin-binding EGF-like growth factor
chr16_+_48657361 0.27 ENST00000565072.1
RP11-42I10.1
RP11-42I10.1
chr6_-_44225231 0.27 ENST00000538577.1
ENST00000537814.1
ENST00000393810.1
ENST00000393812.3
SLC35B2
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
chr19_-_55652290 0.26 ENST00000589745.1
TNNT1
troponin T type 1 (skeletal, slow)
chr15_+_31508174 0.26 ENST00000559292.2
ENST00000557928.1
RP11-16E12.1
RP11-16E12.1
chr12_-_51663959 0.26 ENST00000604188.1
ENST00000398453.3
SMAGP
small cell adhesion glycoprotein
chr9_+_127615733 0.26 ENST00000373574.1
WDR38
WD repeat domain 38
chr16_+_30759700 0.25 ENST00000328273.7
PHKG2
phosphorylase kinase, gamma 2 (testis)
chr11_+_2421718 0.25 ENST00000380996.5
ENST00000333256.6
ENST00000380992.1
ENST00000437110.1
ENST00000435795.1
TSSC4
tumor suppressing subtransferable candidate 4
chr20_-_30311703 0.25 ENST00000450273.1
ENST00000456404.1
ENST00000420488.1
ENST00000439267.1
BCL2L1
BCL2-like 1
chr16_+_30406721 0.24 ENST00000320159.2
ZNF48
zinc finger protein 48
chr14_-_23292596 0.24 ENST00000554741.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr11_-_66103932 0.24 ENST00000311320.4
RIN1
Ras and Rab interactor 1
chr20_+_3801162 0.23 ENST00000379573.2
ENST00000379567.2
ENST00000455742.1
ENST00000246041.2
AP5S1
adaptor-related protein complex 5, sigma 1 subunit
chr12_-_120638902 0.23 ENST00000551150.1
ENST00000313104.5
ENST00000547191.1
ENST00000546989.1
ENST00000392514.4
ENST00000228306.4
ENST00000550856.1
RPLP0
ribosomal protein, large, P0
chr3_+_49209023 0.23 ENST00000332780.2
KLHDC8B
kelch domain containing 8B
chr17_+_7591639 0.23 ENST00000396463.2
WRAP53
WD repeat containing, antisense to TP53
chr2_+_232316906 0.23 ENST00000370380.2
AC017104.2
Uncharacterized protein
chr11_+_46368956 0.23 ENST00000543978.1
DGKZ
diacylglycerol kinase, zeta
chr4_+_56814968 0.22 ENST00000422247.2
CEP135
centrosomal protein 135kDa
chr16_-_22012419 0.22 ENST00000537222.2
ENST00000424898.2
ENST00000286143.6
PDZD9
PDZ domain containing 9
chr19_+_36027660 0.21 ENST00000585510.1
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr17_-_7518145 0.21 ENST00000250113.7
ENST00000571597.1
FXR2
fragile X mental retardation, autosomal homolog 2
chr2_-_24307635 0.21 ENST00000313482.4
TP53I3
tumor protein p53 inducible protein 3
chr10_-_76995675 0.21 ENST00000469299.1
COMTD1
catechol-O-methyltransferase domain containing 1
chr5_+_172571445 0.21 ENST00000231668.9
ENST00000351486.5
ENST00000352523.6
ENST00000393770.4
BNIP1
BCL2/adenovirus E1B 19kDa interacting protein 1
chr10_-_103603677 0.21 ENST00000358038.3
KCNIP2
Kv channel interacting protein 2
chr11_-_72504637 0.21 ENST00000536377.1
ENST00000359373.5
STARD10
ARAP1
StAR-related lipid transfer (START) domain containing 10
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr11_-_66104237 0.20 ENST00000530056.1
RIN1
Ras and Rab interactor 1
chr17_+_38137050 0.20 ENST00000264639.4
PSMD3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr7_+_73082152 0.20 ENST00000324941.4
ENST00000451519.1
VPS37D
vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr15_-_64338521 0.20 ENST00000457488.1
ENST00000558069.1
DAPK2
death-associated protein kinase 2
chr17_+_63133587 0.20 ENST00000449996.3
ENST00000262406.9
RGS9
regulator of G-protein signaling 9
chr12_-_120763739 0.20 ENST00000549767.1
PLA2G1B
phospholipase A2, group IB (pancreas)
chr12_+_110338323 0.20 ENST00000312777.5
ENST00000536408.2
TCHP
trichoplein, keratin filament binding
chr8_+_142264664 0.20 ENST00000518520.1
RP11-10J21.3
Uncharacterized protein
chr3_-_183602515 0.19 ENST00000449306.1
ENST00000435888.1
ENST00000311101.5
ENST00000317096.4
PARL
presenilin associated, rhomboid-like
chr17_-_34122596 0.19 ENST00000250144.8
MMP28
matrix metallopeptidase 28
chr16_-_2390704 0.19 ENST00000301732.5
ENST00000382381.3
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr5_-_125930877 0.19 ENST00000510111.2
ENST00000509270.1
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr1_-_36615051 0.19 ENST00000373163.1
TRAPPC3
trafficking protein particle complex 3
chr16_-_30997533 0.19 ENST00000602217.1
AC135048.1
Uncharacterized protein
chr15_-_44487408 0.19 ENST00000402883.1
ENST00000417257.1
FRMD5
FERM domain containing 5
chr13_-_88323514 0.19 ENST00000441617.1
MIR4500HG
MIR4500 host gene (non-protein coding)
chr12_+_110338063 0.18 ENST00000405876.4
TCHP
trichoplein, keratin filament binding
chr11_-_68611721 0.18 ENST00000561996.1
CPT1A
carnitine palmitoyltransferase 1A (liver)
chr5_-_175461683 0.18 ENST00000514861.1
THOC3
THO complex 3
chr7_+_6629701 0.18 ENST00000359073.5
C7orf26
chromosome 7 open reading frame 26
chr10_-_15762124 0.18 ENST00000378076.3
ITGA8
integrin, alpha 8
chr17_-_33469299 0.18 ENST00000586869.1
ENST00000360831.5
ENST00000442241.4
NLE1
notchless homolog 1 (Drosophila)
chr19_-_1848451 0.18 ENST00000170168.4
REXO1
REX1, RNA exonuclease 1 homolog (S. cerevisiae)
chr11_+_46369077 0.18 ENST00000456247.2
ENST00000421244.2
ENST00000318201.8
DGKZ
diacylglycerol kinase, zeta
chr17_+_74864476 0.18 ENST00000301618.4
ENST00000569840.2
MGAT5B
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
chr9_-_139258235 0.18 ENST00000371738.3
DNLZ
DNL-type zinc finger
chr19_+_49496705 0.18 ENST00000595090.1
RUVBL2
RuvB-like AAA ATPase 2
chr19_+_41860047 0.17 ENST00000604123.1
TMEM91
transmembrane protein 91
chr17_-_19266045 0.17 ENST00000395616.3
B9D1
B9 protein domain 1
chr1_+_151129135 0.17 ENST00000602841.1
SCNM1
sodium channel modifier 1
chr19_+_38893751 0.17 ENST00000588262.1
ENST00000252530.5
ENST00000343358.7
FAM98C
family with sequence similarity 98, member C
chr16_+_58074069 0.17 ENST00000570065.1
MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr10_+_104154229 0.17 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr2_-_24307162 0.17 ENST00000413037.1
ENST00000407482.1
TP53I3
tumor protein p53 inducible protein 3
chr9_+_131901710 0.17 ENST00000524946.2
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr1_+_212208919 0.17 ENST00000366991.4
ENST00000542077.1
DTL
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr14_+_54976603 0.16 ENST00000557317.1
CGRRF1
cell growth regulator with ring finger domain 1
chr11_+_58938903 0.16 ENST00000532982.1
DTX4
deltex homolog 4 (Drosophila)
chr12_+_82752275 0.16 ENST00000248306.3
METTL25
methyltransferase like 25
chr16_+_22308717 0.16 ENST00000299853.5
ENST00000564209.1
ENST00000565358.1
ENST00000418581.2
ENST00000564883.1
ENST00000359210.4
ENST00000563024.1
POLR3E
polymerase (RNA) III (DNA directed) polypeptide E (80kD)
chr19_-_19051927 0.16 ENST00000600077.1
HOMER3
homer homolog 3 (Drosophila)
chrX_-_30326445 0.16 ENST00000378963.1
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr1_+_193091080 0.16 ENST00000367435.3
CDC73
cell division cycle 73
chr9_+_34646651 0.16 ENST00000378842.3
GALT
galactose-1-phosphate uridylyltransferase
chr11_+_46368975 0.15 ENST00000527911.1
DGKZ
diacylglycerol kinase, zeta
chr9_-_134615443 0.15 ENST00000372195.1
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr17_-_1090599 0.15 ENST00000544583.2
ABR
active BCR-related
chr15_+_75074410 0.15 ENST00000439220.2
CSK
c-src tyrosine kinase
chr4_-_140216948 0.15 ENST00000265500.4
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr14_+_105190514 0.15 ENST00000330877.2
ADSSL1
adenylosuccinate synthase like 1
chr19_-_36001286 0.15 ENST00000602679.1
ENST00000492341.2
ENST00000472252.2
ENST00000602781.1
ENST00000402589.2
ENST00000458071.1
ENST00000436012.1
ENST00000443640.1
ENST00000450261.1
ENST00000467637.1
ENST00000480502.1
ENST00000474928.1
ENST00000414866.2
ENST00000392206.2
ENST00000488892.1
DMKN
dermokine
chr11_-_119599794 0.15 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr19_-_6279932 0.15 ENST00000252674.7
MLLT1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr19_+_5690297 0.15 ENST00000582463.1
ENST00000579446.1
ENST00000394580.2
RPL36
ribosomal protein L36
chr22_-_22307199 0.15 ENST00000397495.4
ENST00000263212.5
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr17_-_76183111 0.15 ENST00000405273.1
ENST00000590862.1
ENST00000590430.1
ENST00000586613.1
TK1
thymidine kinase 1, soluble
chr2_+_239067597 0.15 ENST00000546354.1
FAM132B
family with sequence similarity 132, member B
chr9_+_131903916 0.14 ENST00000419582.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr19_+_23945768 0.14 ENST00000486528.1
ENST00000496398.1
RPSAP58
ribosomal protein SA pseudogene 58
chr22_-_22292934 0.14 ENST00000538191.1
ENST00000424647.1
ENST00000407142.1
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr2_-_232395169 0.14 ENST00000305141.4
NMUR1
neuromedin U receptor 1
chr9_+_139685782 0.14 ENST00000290079.8
ENST00000456614.2
TMEM141
RP11-216L13.17
transmembrane protein 141
RP11-216L13.17
chr15_+_63340734 0.14 ENST00000560959.1
TPM1
tropomyosin 1 (alpha)
chr17_-_79827808 0.14 ENST00000580685.1
ARHGDIA
Rho GDP dissociation inhibitor (GDI) alpha
chr1_-_113249678 0.14 ENST00000369633.2
ENST00000425265.2
ENST00000369632.2
ENST00000436685.2
RHOC
ras homolog family member C
chr19_+_49496782 0.14 ENST00000601968.1
ENST00000596837.1
RUVBL2
RuvB-like AAA ATPase 2
chr10_-_6019984 0.14 ENST00000525219.2
IL15RA
interleukin 15 receptor, alpha
chr19_+_5690207 0.14 ENST00000347512.3
RPL36
ribosomal protein L36
chr16_+_29827832 0.14 ENST00000609618.1
PAGR1
PAXIP1-associated glutamate-rich protein 1
chr14_+_52118694 0.14 ENST00000554778.1
FRMD6
FERM domain containing 6
chr11_-_17410869 0.14 ENST00000528731.1
KCNJ11
potassium inwardly-rectifying channel, subfamily J, member 11
chr4_+_186392597 0.14 ENST00000512874.1
RP11-279O9.4
Uncharacterized protein
chr19_+_10527449 0.14 ENST00000592685.1
ENST00000380702.2
PDE4A
phosphodiesterase 4A, cAMP-specific
chr1_+_29563011 0.14 ENST00000345512.3
ENST00000373779.3
ENST00000356870.3
ENST00000323874.8
ENST00000428026.2
ENST00000460170.2
PTPRU
protein tyrosine phosphatase, receptor type, U
chr20_-_1447467 0.14 ENST00000353088.2
ENST00000350991.4
NSFL1C
NSFL1 (p97) cofactor (p47)
chr15_-_44092295 0.14 ENST00000249714.3
ENST00000299969.6
ENST00000319327.6
SERINC4
serine incorporator 4
chr1_+_154244987 0.14 ENST00000328703.7
ENST00000457918.2
ENST00000483970.2
ENST00000435087.1
ENST00000532105.1
HAX1
HCLS1 associated protein X-1
chr19_-_55653259 0.14 ENST00000593194.1
TNNT1
troponin T type 1 (skeletal, slow)
chr19_-_19754404 0.13 ENST00000587205.1
ENST00000445806.2
ENST00000203556.4
GMIP
GEM interacting protein
chr2_-_74710078 0.13 ENST00000290418.4
CCDC142
coiled-coil domain containing 142
chr11_+_64216546 0.13 ENST00000316124.2
AP003774.4
HCG1652096, isoform CRA_a; Uncharacterized protein; cDNA FLJ37045 fis, clone BRACE2012185
chr10_+_81107216 0.13 ENST00000394579.3
ENST00000225174.3
PPIF
peptidylprolyl isomerase F
chr16_+_29827285 0.13 ENST00000320330.6
PAGR1
PAXIP1 associated glutamate-rich protein 1
chr19_+_12949251 0.13 ENST00000251472.4
MAST1
microtubule associated serine/threonine kinase 1
chr17_+_41561317 0.13 ENST00000540306.1
ENST00000262415.3
ENST00000605777.1
DHX8
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr10_-_79789291 0.13 ENST00000372371.3
POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr11_+_120039685 0.13 ENST00000530303.1
ENST00000319763.1
AP000679.2
Uncharacterized protein
chr6_+_151186554 0.13 ENST00000367321.3
ENST00000367307.4
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr7_+_6629621 0.13 ENST00000344417.5
C7orf26
chromosome 7 open reading frame 26
chr1_+_200860122 0.13 ENST00000532631.1
ENST00000451872.2
C1orf106
chromosome 1 open reading frame 106
chr6_-_41703296 0.12 ENST00000373033.1
TFEB
transcription factor EB
chr11_+_777562 0.12 ENST00000530083.1
AP006621.5
Protein LOC100506518
chr22_-_32808194 0.12 ENST00000451746.2
ENST00000216038.5
RTCB
RNA 2',3'-cyclic phosphate and 5'-OH ligase
chr15_-_45480147 0.12 ENST00000560734.1
SHF
Src homology 2 domain containing F
chr6_+_35310312 0.12 ENST00000448077.2
ENST00000360694.3
ENST00000418635.2
ENST00000444397.1
PPARD
peroxisome proliferator-activated receptor delta
chr8_+_42948641 0.12 ENST00000518991.1
ENST00000331373.5
POMK
protein-O-mannose kinase
chr7_+_6655225 0.12 ENST00000457543.3
ZNF853
zinc finger protein 853
chr5_+_176514413 0.12 ENST00000513166.1
FGFR4
fibroblast growth factor receptor 4
chr18_+_596982 0.12 ENST00000579912.1
ENST00000400606.2
ENST00000540035.1
CLUL1
clusterin-like 1 (retinal)
chr12_-_89413456 0.12 ENST00000500381.2
RP11-13A1.1
RP11-13A1.1
chr1_-_145589424 0.12 ENST00000334513.5
NUDT17
nudix (nucleoside diphosphate linked moiety X)-type motif 17
chr8_-_30670053 0.12 ENST00000518564.1
PPP2CB
protein phosphatase 2, catalytic subunit, beta isozyme
chr12_+_49208234 0.12 ENST00000540990.1
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr16_+_75032901 0.11 ENST00000335325.4
ENST00000320619.6
ZNRF1
zinc and ring finger 1, E3 ubiquitin protein ligase
chr7_+_1126461 0.11 ENST00000297469.3
GPER1
G protein-coupled estrogen receptor 1
chr15_+_63340775 0.11 ENST00000559281.1
ENST00000317516.7
TPM1
tropomyosin 1 (alpha)
chr8_-_27850180 0.11 ENST00000380385.2
ENST00000301906.4
ENST00000354914.3
SCARA5
scavenger receptor class A, member 5 (putative)
chr12_-_51663728 0.11 ENST00000603864.1
ENST00000605426.1
SMAGP
small cell adhesion glycoprotein
chr9_-_123239632 0.11 ENST00000416449.1
CDK5RAP2
CDK5 regulatory subunit associated protein 2
chr12_-_7245125 0.11 ENST00000542285.1
ENST00000540610.1
C1R
complement component 1, r subcomponent
chr15_-_45480153 0.11 ENST00000560471.1
ENST00000560540.1
SHF
Src homology 2 domain containing F
chr5_-_141257954 0.11 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
PCDH1
protocadherin 1
chr1_-_109655355 0.11 ENST00000369945.3
C1orf194
chromosome 1 open reading frame 194
chr16_+_67678818 0.11 ENST00000334583.6
RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr2_-_166060552 0.11 ENST00000283254.7
ENST00000453007.1
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr12_-_56320887 0.11 ENST00000398213.4
WIBG
within bgcn homolog (Drosophila)
chr1_-_113249734 0.10 ENST00000484054.3
ENST00000369636.2
ENST00000369637.1
ENST00000285735.2
ENST00000369638.2
RHOC
ras homolog family member C
chr16_+_89642120 0.10 ENST00000268720.5
ENST00000319518.8
CPNE7
copine VII
chr5_-_146833222 0.10 ENST00000534907.1
DPYSL3
dihydropyrimidinase-like 3
chr17_-_61778528 0.10 ENST00000584645.1
LIMD2
LIM domain containing 2
chr6_-_83775489 0.10 ENST00000369747.3
UBE3D
ubiquitin protein ligase E3D
chr19_+_16222678 0.10 ENST00000586682.1
RAB8A
RAB8A, member RAS oncogene family
chr22_+_22901750 0.10 ENST00000407120.1
LL22NC03-63E9.3
Uncharacterized protein
chr10_-_15413035 0.10 ENST00000378116.4
ENST00000455654.1
FAM171A1
family with sequence similarity 171, member A1
chr7_+_1126437 0.10 ENST00000413368.1
ENST00000397092.1
GPER1
G protein-coupled estrogen receptor 1
chr1_-_6614565 0.10 ENST00000377705.5
NOL9
nucleolar protein 9
chr1_-_150533969 0.10 ENST00000369035.2
ADAMTSL4-AS1
ADAMTSL4 antisense RNA 1
chr19_-_58400148 0.10 ENST00000595048.1
ENST00000600634.1
ENST00000595295.1
ENST00000596604.1
ENST00000597342.1
ENST00000597807.1
ZNF814
zinc finger protein 814
chr7_-_22539771 0.10 ENST00000406890.2
ENST00000424363.1
STEAP1B
STEAP family member 1B
chr11_+_61447845 0.10 ENST00000257215.5
DAGLA
diacylglycerol lipase, alpha
chr16_-_790887 0.10 ENST00000540986.1
NARFL
nuclear prelamin A recognition factor-like
chr2_-_166060571 0.10 ENST00000360093.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr8_-_145550571 0.10 ENST00000332324.4
DGAT1
diacylglycerol O-acyltransferase 1
chr8_-_42358742 0.10 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr1_+_10490127 0.10 ENST00000602787.1
ENST00000602296.1
ENST00000400900.2
APITD1
APITD1-CORT
apoptosis-inducing, TAF9-like domain 1
APITD1-CORT readthrough
chr17_+_19912640 0.10 ENST00000395527.4
ENST00000583482.2
ENST00000583528.1
ENST00000583463.1
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr17_-_34890037 0.10 ENST00000589404.1
MYO19
myosin XIX
chr17_-_19265982 0.10 ENST00000268841.6
ENST00000261499.4
ENST00000575478.1
B9D1
B9 protein domain 1
chr14_-_93582148 0.10 ENST00000267615.6
ENST00000553452.1
ITPK1
inositol-tetrakisphosphate 1-kinase
chrX_-_71497077 0.10 ENST00000373626.3
RPS4X
ribosomal protein S4, X-linked
chr17_-_33446735 0.10 ENST00000460118.2
ENST00000335858.7
RAD51D
RAD51 paralog D
chr16_-_88851618 0.10 ENST00000301015.9
PIEZO1
piezo-type mechanosensitive ion channel component 1

Network of associatons between targets according to the STRING database.

First level regulatory network of RAD21_SMC3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0032203 telomere formation via telomerase(GO:0032203)
0.1 0.4 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.5 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 0.3 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.1 0.3 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.3 GO:1902559 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.1 0.5 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.3 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 0.5 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.2 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264)
0.1 0.2 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.1 0.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.3 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.4 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 0.3 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.2 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.1 0.3 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.2 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.2 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.3 GO:1903412 response to bile acid(GO:1903412)
0.0 0.4 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.2 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.3 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.0 0.2 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.2 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.2 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.2 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.1 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.0 0.1 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.2 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:0098917 diacylglycerol catabolic process(GO:0046340) retrograde trans-synaptic signaling(GO:0098917)
0.0 0.2 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.6 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.3 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.4 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.1 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.0 0.4 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.1 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.1 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.2 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.5 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.3 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.1 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.0 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.1 GO:0051351 positive regulation of ligase activity(GO:0051351)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 GO:0016234 inclusion body(GO:0016234)
0.1 0.1 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.0 0.2 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.4 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.0 0.3 GO:0097255 R2TP complex(GO:0097255)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0097361 CIA complex(GO:0097361)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.4 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0032153 cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.4 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031862 prostanoid receptor binding(GO:0031862)
0.1 0.1 GO:0016723 cupric reductase activity(GO:0008823) oxidoreductase activity, oxidizing metal ions(GO:0016722) oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.3 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.2 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.1 0.2 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.1 0.2 GO:0047325 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.1 0.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.0 0.3 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.4 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.3 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.4 GO:0031014 troponin T binding(GO:0031014)
0.0 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0004797 thymidine kinase activity(GO:0004797)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.1 GO:0030984 kininogen binding(GO:0030984)
0.0 0.1 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.6 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.0 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.7 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.0 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.0 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.5 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.8 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis