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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for REL

Z-value: 0.98

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Transcription factors associated with REL

Gene Symbol Gene ID Gene Info
REL
ENSG00000162924.9 REL proto-oncogene, NF-kB subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RELhg19_v2_chr2_+_61108650_61108687-0.435.7e-01Click!

Activity profile of REL motif

Sorted Z-values of REL motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_191885686 1.35 ENST00000432058.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr6_+_138188351 0.86 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr6_+_138188551 0.80 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr6_+_138188378 0.79 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr8_-_23712312 0.75 ENST00000290271.2
STC1
stanniocalcin 1
chr5_-_150467221 0.71 ENST00000522226.1
TNIP1
TNFAIP3 interacting protein 1
chr2_-_163175133 0.65 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr11_+_102188272 0.59 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr19_+_4229495 0.58 ENST00000221847.5
EBI3
Epstein-Barr virus induced 3
chr5_-_150460914 0.56 ENST00000389378.2
TNIP1
TNFAIP3 interacting protein 1
chr4_-_76957214 0.55 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr14_+_103589789 0.52 ENST00000558056.1
ENST00000560869.1
TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr3_+_183967409 0.51 ENST00000324557.4
ENST00000402825.3
ECE2
endothelin converting enzyme 2
chr17_-_15469590 0.50 ENST00000312127.2
CDRT1
CMT duplicated region transcript 1; Uncharacterized protein
chr10_+_104155450 0.50 ENST00000471698.1
ENST00000189444.6
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr10_+_99609996 0.50 ENST00000370602.1
GOLGA7B
golgin A7 family, member B
chr6_-_32821599 0.49 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr4_-_74864386 0.48 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr6_+_32821924 0.47 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr18_+_21529811 0.45 ENST00000588004.1
LAMA3
laminin, alpha 3
chr22_+_22676808 0.43 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr14_-_24616426 0.43 ENST00000216802.5
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr5_+_118604385 0.42 ENST00000274456.6
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr5_-_150466692 0.41 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNIP1
TNFAIP3 interacting protein 1
chr11_+_102188224 0.39 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chr9_-_136344197 0.39 ENST00000414172.1
ENST00000371897.4
SLC2A6
solute carrier family 2 (facilitated glucose transporter), member 6
chr19_-_46272462 0.39 ENST00000317578.6
SIX5
SIX homeobox 5
chr17_+_40440481 0.38 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A
signal transducer and activator of transcription 5A
chr15_+_67430339 0.37 ENST00000439724.3
SMAD3
SMAD family member 3
chr14_+_24616588 0.37 ENST00000324103.6
ENST00000559260.1
RNF31
ring finger protein 31
chr18_+_33877654 0.36 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
FHOD3
formin homology 2 domain containing 3
chr10_-_18948208 0.35 ENST00000607346.1
ARL5B-AS1
ARL5B antisense RNA 1
chr20_-_45530365 0.35 ENST00000414085.1
RP11-323C15.2
RP11-323C15.2
chr1_-_6453426 0.35 ENST00000545482.1
ACOT7
acyl-CoA thioesterase 7
chr10_+_104154229 0.33 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr9_-_84303269 0.33 ENST00000418319.1
TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr22_+_46546406 0.32 ENST00000440343.1
ENST00000415785.1
PPARA
peroxisome proliferator-activated receptor alpha
chr19_-_46272106 0.32 ENST00000560168.1
SIX5
SIX homeobox 5
chr4_+_74735102 0.31 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr2_+_201987200 0.31 ENST00000425030.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr19_+_41725088 0.30 ENST00000301178.4
AXL
AXL receptor tyrosine kinase
chr12_+_51632638 0.30 ENST00000549732.2
DAZAP2
DAZ associated protein 2
chr22_+_46067678 0.29 ENST00000381061.4
ENST00000252934.5
ATXN10
ataxin 10
chr19_+_35940486 0.29 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr14_+_103243813 0.29 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
TRAF3
TNF receptor-associated factor 3
chr10_-_97050777 0.28 ENST00000329399.6
PDLIM1
PDZ and LIM domain 1
chr6_+_15401075 0.28 ENST00000541660.1
JARID2
jumonji, AT rich interactive domain 2
chr3_-_156878482 0.28 ENST00000295925.4
CCNL1
cyclin L1
chr18_+_21452964 0.28 ENST00000587184.1
LAMA3
laminin, alpha 3
chr16_+_27325202 0.28 ENST00000395762.2
ENST00000562142.1
ENST00000561742.1
ENST00000543915.2
ENST00000449195.1
ENST00000380922.3
ENST00000563002.1
IL4R
interleukin 4 receptor
chr8_-_123793048 0.28 ENST00000607710.1
RP11-44N11.2
RP11-44N11.2
chr11_+_10476851 0.28 ENST00000396553.2
AMPD3
adenosine monophosphate deaminase 3
chr1_-_27816556 0.28 ENST00000536657.1
WASF2
WAS protein family, member 2
chr18_+_21452804 0.27 ENST00000269217.6
LAMA3
laminin, alpha 3
chr16_+_31044812 0.27 ENST00000313843.3
STX4
syntaxin 4
chr14_-_35873856 0.27 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr1_+_16767195 0.27 ENST00000504551.2
ENST00000457722.2
ENST00000406746.1
ENST00000443980.2
NECAP2
NECAP endocytosis associated 2
chr20_+_43803517 0.27 ENST00000243924.3
PI3
peptidase inhibitor 3, skin-derived
chr5_+_14143728 0.27 ENST00000344204.4
ENST00000537187.1
TRIO
trio Rho guanine nucleotide exchange factor
chr19_+_41725140 0.27 ENST00000359092.3
AXL
AXL receptor tyrosine kinase
chr12_-_96793142 0.26 ENST00000552262.1
ENST00000551816.1
ENST00000552496.1
CDK17
cyclin-dependent kinase 17
chr4_-_185395191 0.26 ENST00000510814.1
ENST00000507523.1
ENST00000506230.1
IRF2
interferon regulatory factor 2
chr11_-_74800799 0.26 ENST00000305159.3
OR2AT4
olfactory receptor, family 2, subfamily AT, member 4
chr2_-_113594279 0.25 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr15_+_57891609 0.25 ENST00000569089.1
MYZAP
myocardial zonula adherens protein
chr1_-_89738528 0.25 ENST00000343435.5
GBP5
guanylate binding protein 5
chr11_-_61734599 0.24 ENST00000532601.1
FTH1
ferritin, heavy polypeptide 1
chr14_-_103589246 0.23 ENST00000558224.1
ENST00000560742.1
LINC00677
long intergenic non-protein coding RNA 677
chr2_+_228678550 0.23 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr16_-_88717482 0.23 ENST00000261623.3
CYBA
cytochrome b-245, alpha polypeptide
chr12_-_76425368 0.22 ENST00000602540.1
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr6_-_44233361 0.22 ENST00000275015.5
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr2_+_202047596 0.22 ENST00000286186.6
ENST00000360132.3
CASP10
caspase 10, apoptosis-related cysteine peptidase
chr10_+_13142075 0.21 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
OPTN
optineurin
chr2_+_102314161 0.21 ENST00000425019.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr17_-_4852332 0.21 ENST00000572383.1
PFN1
profilin 1
chr1_-_226595648 0.20 ENST00000366790.3
PARP1
poly (ADP-ribose) polymerase 1
chr16_+_67282853 0.20 ENST00000299798.11
SLC9A5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr10_+_13141585 0.20 ENST00000378764.2
OPTN
optineurin
chr16_+_27324983 0.20 ENST00000566117.1
IL4R
interleukin 4 receptor
chr2_-_220094031 0.19 ENST00000443140.1
ENST00000432520.1
ENST00000409618.1
ATG9A
autophagy related 9A
chr1_-_209824643 0.19 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr3_+_101546827 0.19 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr10_+_90750493 0.19 ENST00000357339.2
ENST00000355279.2
FAS
Fas cell surface death receptor
chr21_+_34775181 0.19 ENST00000290219.6
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr14_+_75988768 0.19 ENST00000286639.6
BATF
basic leucine zipper transcription factor, ATF-like
chr14_-_35099315 0.19 ENST00000396526.3
ENST00000396534.3
ENST00000355110.5
ENST00000557265.1
SNX6
sorting nexin 6
chr21_+_34775698 0.19 ENST00000381995.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr1_-_9189144 0.18 ENST00000414642.2
GPR157
G protein-coupled receptor 157
chr5_-_149792295 0.18 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr2_+_16080659 0.18 ENST00000281043.3
MYCN
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr2_+_220094479 0.18 ENST00000323348.5
ENST00000453432.1
ENST00000409849.1
ENST00000416565.1
ENST00000410034.3
ENST00000447157.1
ANKZF1
ankyrin repeat and zinc finger domain containing 1
chr18_+_3252265 0.18 ENST00000580887.1
ENST00000536605.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr1_-_8086343 0.18 ENST00000474874.1
ENST00000469499.1
ENST00000377482.5
ERRFI1
ERBB receptor feedback inhibitor 1
chr3_-_139108463 0.17 ENST00000512242.1
COPB2
coatomer protein complex, subunit beta 2 (beta prime)
chr9_+_101705893 0.17 ENST00000375001.3
COL15A1
collagen, type XV, alpha 1
chr2_+_202047843 0.17 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
CASP10
caspase 10, apoptosis-related cysteine peptidase
chr11_-_65359947 0.17 ENST00000597463.1
AP001362.1
Uncharacterized protein
chr5_+_10564432 0.17 ENST00000296657.5
ANKRD33B
ankyrin repeat domain 33B
chr10_+_13142225 0.17 ENST00000378747.3
OPTN
optineurin
chr14_-_69446034 0.17 ENST00000193403.6
ACTN1
actinin, alpha 1
chr4_+_185395947 0.17 ENST00000605834.1
RP11-326I11.3
RP11-326I11.3
chr1_+_144339738 0.17 ENST00000538264.1
AL592284.1
Protein LOC642441
chr17_+_40985407 0.17 ENST00000586114.1
ENST00000590720.1
ENST00000585805.1
ENST00000541124.1
ENST00000441946.2
ENST00000591152.1
ENST00000589469.1
ENST00000293362.3
ENST00000592169.1
PSME3
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr2_-_177502659 0.16 ENST00000295549.4
AC017048.3
long intergenic non-protein coding RNA 1116
chr21_+_34775772 0.16 ENST00000405436.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr17_+_26662730 0.16 ENST00000226225.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr11_+_66406149 0.16 ENST00000578778.1
ENST00000483858.1
ENST00000398692.4
ENST00000510173.2
ENST00000506523.2
ENST00000530235.1
ENST00000532968.1
RBM4
RNA binding motif protein 4
chr3_-_156878540 0.16 ENST00000461804.1
CCNL1
cyclin L1
chr9_+_127054254 0.16 ENST00000422297.1
NEK6
NIMA-related kinase 6
chr11_-_128392085 0.16 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chrX_-_153599578 0.16 ENST00000360319.4
ENST00000344736.4
FLNA
filamin A, alpha
chr2_+_204193129 0.15 ENST00000417864.1
ABI2
abl-interactor 2
chr6_+_29910301 0.15 ENST00000376809.5
ENST00000376802.2
HLA-A
major histocompatibility complex, class I, A
chr3_+_47844615 0.15 ENST00000348968.4
DHX30
DEAH (Asp-Glu-Ala-His) box helicase 30
chr9_+_130911723 0.15 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2
lipocalin 2
chr9_-_115095851 0.15 ENST00000343327.2
PTBP3
polypyrimidine tract binding protein 3
chr1_-_235813290 0.15 ENST00000391854.2
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr17_-_76356148 0.15 ENST00000587578.1
ENST00000330871.2
SOCS3
suppressor of cytokine signaling 3
chr17_+_40440094 0.15 ENST00000546010.2
STAT5A
signal transducer and activator of transcription 5A
chrX_+_115567767 0.14 ENST00000371900.4
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr9_+_130547958 0.14 ENST00000421939.1
ENST00000373265.2
CDK9
cyclin-dependent kinase 9
chr6_+_32121908 0.14 ENST00000375143.2
ENST00000424499.1
PPT2
palmitoyl-protein thioesterase 2
chr22_+_46731596 0.14 ENST00000381019.3
TRMU
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
chr2_-_220094294 0.14 ENST00000436856.1
ENST00000428226.1
ENST00000409422.1
ENST00000431715.1
ENST00000457841.1
ENST00000439812.1
ENST00000361242.4
ENST00000396761.2
ATG9A
autophagy related 9A
chr1_-_113249948 0.14 ENST00000339083.7
ENST00000369642.3
RHOC
ras homolog family member C
chr1_+_110453109 0.14 ENST00000525659.1
CSF1
colony stimulating factor 1 (macrophage)
chr4_+_74702214 0.14 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr12_+_56211703 0.14 ENST00000243045.5
ENST00000552672.1
ENST00000550836.1
ORMDL2
ORM1-like 2 (S. cerevisiae)
chr16_+_3014217 0.13 ENST00000572045.1
KREMEN2
kringle containing transmembrane protein 2
chr15_+_44719790 0.13 ENST00000558791.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr9_+_130911770 0.13 ENST00000372998.1
LCN2
lipocalin 2
chr5_+_154136702 0.13 ENST00000524248.1
LARP1
La ribonucleoprotein domain family, member 1
chr19_+_11466062 0.13 ENST00000251473.5
ENST00000591329.1
ENST00000586380.1
DKFZP761J1410
Lipid phosphate phosphatase-related protein type 2
chr2_+_204193149 0.13 ENST00000422511.2
ABI2
abl-interactor 2
chr8_+_42128861 0.13 ENST00000518983.1
IKBKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr2_+_120301997 0.13 ENST00000602047.1
PCDP1
Primary ciliary dyskinesia protein 1
chr2_+_208394794 0.13 ENST00000536726.1
ENST00000374397.4
ENST00000452474.1
CREB1
cAMP responsive element binding protein 1
chr19_-_4831701 0.12 ENST00000248244.5
TICAM1
toll-like receptor adaptor molecule 1
chr16_-_75498553 0.12 ENST00000569276.1
ENST00000357613.4
ENST00000561878.1
ENST00000566980.1
ENST00000567194.1
TMEM170A
RP11-77K12.1
transmembrane protein 170A
Uncharacterized protein
chr4_-_134070250 0.12 ENST00000505289.1
ENST00000509715.1
RP11-9G1.3
RP11-9G1.3
chr1_-_29508321 0.12 ENST00000546138.1
SRSF4
serine/arginine-rich splicing factor 4
chr12_+_51633061 0.12 ENST00000551313.1
DAZAP2
DAZ associated protein 2
chr8_-_49833978 0.12 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr1_-_32403903 0.12 ENST00000344035.6
ENST00000356536.3
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr6_-_131291572 0.12 ENST00000529208.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr13_+_53602894 0.12 ENST00000219022.2
OLFM4
olfactomedin 4
chr11_-_72492878 0.12 ENST00000535054.1
ENST00000545082.1
STARD10
StAR-related lipid transfer (START) domain containing 10
chr1_+_235530675 0.12 ENST00000366601.3
ENST00000406207.1
ENST00000543662.1
TBCE
tubulin folding cofactor E
chr4_-_103749179 0.12 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr12_-_57504069 0.12 ENST00000543873.2
ENST00000554663.1
ENST00000557635.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr14_-_35099377 0.11 ENST00000362031.4
SNX6
sorting nexin 6
chr4_-_185395672 0.11 ENST00000393593.3
IRF2
interferon regulatory factor 2
chr19_+_41256764 0.11 ENST00000243563.3
ENST00000601253.1
ENST00000597353.1
ENST00000599362.1
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr11_+_66406088 0.11 ENST00000310092.7
ENST00000396053.4
ENST00000408993.2
RBM4
RNA binding motif protein 4
chr5_-_141703713 0.11 ENST00000511815.1
SPRY4
sprouty homolog 4 (Drosophila)
chr3_+_197518100 0.11 ENST00000438796.2
ENST00000414675.2
ENST00000441090.2
ENST00000334859.4
ENST00000425562.2
LRCH3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr22_-_39151434 0.11 ENST00000439339.1
SUN2
Sad1 and UNC84 domain containing 2
chr17_-_6338472 0.11 ENST00000570466.1
ENST00000576776.1
ENST00000576307.1
ENST00000381129.3
ENST00000250087.5
AIPL1
aryl hydrocarbon receptor interacting protein-like 1
chr1_-_27816641 0.11 ENST00000430629.2
WASF2
WAS protein family, member 2
chr15_+_44719970 0.11 ENST00000558966.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr16_-_2059748 0.10 ENST00000562103.1
ENST00000431526.1
ZNF598
zinc finger protein 598
chr4_-_146101304 0.10 ENST00000447906.2
OTUD4
OTU domain containing 4
chr6_-_31774714 0.10 ENST00000375661.5
LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr15_-_74753443 0.10 ENST00000567435.1
ENST00000564488.1
ENST00000565130.1
ENST00000563081.1
ENST00000565335.1
ENST00000395081.2
ENST00000361351.4
UBL7
ubiquitin-like 7 (bone marrow stromal cell-derived)
chr2_-_128145498 0.10 ENST00000409179.2
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr21_-_34915084 0.10 ENST00000426819.1
GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr10_+_30723045 0.10 ENST00000542547.1
ENST00000415139.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr9_+_127054217 0.10 ENST00000394199.2
ENST00000546191.1
NEK6
NIMA-related kinase 6
chr8_-_49834299 0.10 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr9_-_34637806 0.10 ENST00000477726.1
SIGMAR1
sigma non-opioid intracellular receptor 1
chr6_+_32121789 0.09 ENST00000437001.2
ENST00000375137.2
PPT2
palmitoyl-protein thioesterase 2
chr3_+_57261859 0.09 ENST00000495803.1
ENST00000444459.1
APPL1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr22_+_46731676 0.09 ENST00000424260.2
TRMU
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
chr2_+_87808725 0.09 ENST00000413202.1
LINC00152
long intergenic non-protein coding RNA 152
chr7_+_102715315 0.09 ENST00000428183.2
ENST00000323716.3
ENST00000441711.2
ENST00000454559.1
ENST00000425331.1
ENST00000541300.1
ARMC10
armadillo repeat containing 10
chr12_-_117537240 0.09 ENST00000392545.4
ENST00000541210.1
ENST00000335209.7
TESC
tescalcin
chr4_-_54930790 0.09 ENST00000263921.3
CHIC2
cysteine-rich hydrophobic domain 2
chr3_+_141596371 0.09 ENST00000495216.1
ATP1B3
ATPase, Na+/K+ transporting, beta 3 polypeptide
chr17_-_37382105 0.09 ENST00000333461.5
STAC2
SH3 and cysteine rich domain 2
chr4_+_26322185 0.09 ENST00000361572.6
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr16_-_88717423 0.09 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
CYBA
cytochrome b-245, alpha polypeptide
chr6_-_30080863 0.08 ENST00000540829.1
TRIM31
tripartite motif containing 31
chr20_+_44746939 0.08 ENST00000372276.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr1_-_32229934 0.08 ENST00000398542.1
BAI2
brain-specific angiogenesis inhibitor 2
chr2_+_208394455 0.08 ENST00000430624.1
CREB1
cAMP responsive element binding protein 1
chr17_-_8286484 0.08 ENST00000582556.1
ENST00000584164.1
ENST00000293842.5
ENST00000584343.1
ENST00000578812.1
ENST00000583011.1
RPL26
ribosomal protein L26
chr1_-_8000872 0.08 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr19_-_14064114 0.08 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
PODNL1
podocan-like 1
chr3_+_52719936 0.08 ENST00000418458.1
ENST00000394799.2
GNL3
guanine nucleotide binding protein-like 3 (nucleolar)
chr4_-_74904398 0.07 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr16_-_122619 0.07 ENST00000262316.6
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr7_+_143771275 0.07 ENST00000408898.2
OR2A25
olfactory receptor, family 2, subfamily A, member 25
chr1_+_207262170 0.07 ENST00000367078.3
C4BPB
complement component 4 binding protein, beta
chr15_+_44719996 0.07 ENST00000559793.1
ENST00000558968.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr1_+_6845384 0.07 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr2_-_68694390 0.07 ENST00000377957.3
FBXO48
F-box protein 48
chr2_-_27357479 0.07 ENST00000406567.3
ENST00000260643.2
PREB
prolactin regulatory element binding
chr7_+_18548878 0.07 ENST00000456174.2
HDAC9
histone deacetylase 9
chr2_-_114647327 0.07 ENST00000602760.1
RP11-141B14.1
RP11-141B14.1

Network of associatons between targets according to the STRING database.

First level regulatory network of REL

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0072573 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.3 1.3 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.3 1.7 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.2 0.2 GO:0045210 FasL biosynthetic process(GO:0045210)
0.2 0.8 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.2 0.7 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.2 0.7 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.5 GO:0046967 cytosol to ER transport(GO:0046967)
0.1 0.5 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 0.3 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.1 0.6 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.1 0.3 GO:0043309 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.3 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.3 GO:0036116 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.2 GO:0072616 interleukin-18 secretion(GO:0072616)
0.1 1.0 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.1 1.0 GO:0060536 cartilage morphogenesis(GO:0060536)
0.1 0.1 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.1 0.2 GO:0045362 interleukin-1 biosynthetic process(GO:0042222) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.4 GO:0023035 CD40 signaling pathway(GO:0023035)
0.1 0.6 GO:0014805 smooth muscle adaptation(GO:0014805)
0.1 0.4 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.1 0.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 0.6 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.3 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.1 GO:1902534 single-organism membrane invagination(GO:1902534)
0.1 0.3 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.5 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.4 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.2 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 1.2 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.3 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.5 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.3 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.2 GO:1903243 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.0 1.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.4 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.2 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.1 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)
0.0 0.3 GO:1903943 negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.3 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.1 GO:1901355 cellular response to rapamycin(GO:0072752) response to rapamycin(GO:1901355)
0.0 0.2 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.2 GO:0030578 PML body organization(GO:0030578)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.6 GO:0010002 cardioblast differentiation(GO:0010002)
0.0 0.2 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.3 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.3 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.2 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 0.2 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.4 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.1 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.5 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:0098502 DNA dephosphorylation(GO:0098502)
0.0 0.1 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.2 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.4 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.3 GO:0007620 copulation(GO:0007620)
0.0 0.1 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.1 GO:0032415 regulation of sodium:proton antiporter activity(GO:0032415) positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.1 GO:1902231 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0032907 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.0 GO:1902523 activation of MAPK activity involved in innate immune response(GO:0035419) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.1 GO:0003360 brainstem development(GO:0003360)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 1.2 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.6 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.5 GO:0042825 TAP complex(GO:0042825)
0.1 0.4 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.2 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.1 0.5 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.2 GO:0031523 Myb complex(GO:0031523)
0.0 0.3 GO:0097422 tubular endosome(GO:0097422)
0.0 0.8 GO:0097342 ripoptosome(GO:0097342)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.5 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.6 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.6 GO:0033643 host cell part(GO:0033643)
0.0 0.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.3 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.2 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 2.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.5 GO:0004913 interleukin-4 receptor activity(GO:0004913)
0.1 1.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.3 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.1 0.5 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 0.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.5 GO:0046979 TAP2 binding(GO:0046979)
0.1 0.3 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.4 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 0.4 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 1.3 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.1 GO:0004644 phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.0 2.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.3 GO:0034452 dynactin binding(GO:0034452)
0.0 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.5 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 5.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.1 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.5 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID CD40 PATHWAY CD40/CD40L signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.9 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 3.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.1 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage