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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for RREB1

Z-value: 0.93

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Transcription factors associated with RREB1

Gene Symbol Gene ID Gene Info
RREB1
ENSG00000124782.15 ras responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RREB1hg19_v2_chr6_+_7108210_71082640.396.1e-01Click!

Activity profile of RREB1 motif

Sorted Z-values of RREB1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_37976082 1.29 ENST00000215886.4
LGALS2
lectin, galactoside-binding, soluble, 2
chr17_-_7082861 0.67 ENST00000269299.3
ASGR1
asialoglycoprotein receptor 1
chr1_+_212782012 0.64 ENST00000341491.4
ENST00000366985.1
ATF3
activating transcription factor 3
chr9_-_116861337 0.61 ENST00000374118.3
KIF12
kinesin family member 12
chr15_+_21145765 0.57 ENST00000553416.1
CT60
cancer/testis antigen 60 (non-protein coding)
chr7_+_91570240 0.55 ENST00000394564.1
AKAP9
A kinase (PRKA) anchor protein 9
chr11_+_86511569 0.54 ENST00000441050.1
PRSS23
protease, serine, 23
chr11_-_75062829 0.45 ENST00000393505.4
ARRB1
arrestin, beta 1
chr11_-_75062730 0.43 ENST00000420843.2
ENST00000360025.3
ARRB1
arrestin, beta 1
chr3_+_187461442 0.42 ENST00000450760.1
RP11-211G3.2
RP11-211G3.2
chr11_+_111896320 0.41 ENST00000531306.1
ENST00000537636.1
DLAT
dihydrolipoamide S-acetyltransferase
chr11_+_111896090 0.41 ENST00000393051.1
DLAT
dihydrolipoamide S-acetyltransferase
chr6_-_86353510 0.40 ENST00000444272.1
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr17_-_72864739 0.39 ENST00000579893.1
ENST00000544854.1
FDXR
ferredoxin reductase
chrX_-_77041685 0.39 ENST00000373344.5
ENST00000395603.3
ATRX
alpha thalassemia/mental retardation syndrome X-linked
chr20_+_57875457 0.37 ENST00000337938.2
ENST00000311585.7
ENST00000371028.2
EDN3
endothelin 3
chr12_-_53297432 0.36 ENST00000546900.1
KRT8
keratin 8
chr5_+_92228 0.36 ENST00000512035.1
CTD-2231H16.1
CTD-2231H16.1
chr5_+_78908388 0.34 ENST00000296783.3
PAPD4
PAP associated domain containing 4
chr9_-_14313893 0.34 ENST00000380921.3
ENST00000380959.3
NFIB
nuclear factor I/B
chr8_+_26149274 0.34 ENST00000522535.1
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr7_+_91570165 0.33 ENST00000356239.3
ENST00000359028.2
ENST00000358100.2
AKAP9
A kinase (PRKA) anchor protein 9
chrX_+_151867214 0.33 ENST00000329342.5
ENST00000412733.1
ENST00000457643.1
MAGEA6
melanoma antigen family A, 6
chr19_+_41305612 0.33 ENST00000594380.1
ENST00000593397.1
ENST00000601733.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr2_-_32236002 0.32 ENST00000404530.1
MEMO1
mediator of cell motility 1
chr19_-_36288740 0.32 ENST00000564335.1
ENST00000567313.1
ENST00000433059.1
AC002398.5
AC002398.5
chr12_+_96588368 0.31 ENST00000547860.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr5_+_78908233 0.31 ENST00000453514.1
ENST00000423041.2
ENST00000504233.1
ENST00000428308.2
PAPD4
PAP associated domain containing 4
chr2_+_85661918 0.30 ENST00000340326.2
SH2D6
SH2 domain containing 6
chr22_+_41968007 0.30 ENST00000460790.1
CSDC2
cold shock domain containing C2, RNA binding
chr19_+_40973049 0.30 ENST00000598249.1
ENST00000338932.3
ENST00000344104.3
SPTBN4
spectrin, beta, non-erythrocytic 4
chr6_-_136847610 0.30 ENST00000454590.1
ENST00000432797.2
MAP7
microtubule-associated protein 7
chr19_-_30206128 0.30 ENST00000392276.1
ENST00000592153.1
ENST00000323670.9
C19orf12
chromosome 19 open reading frame 12
chr7_+_94537542 0.29 ENST00000433881.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr16_+_68771128 0.28 ENST00000261769.5
ENST00000422392.2
CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr1_-_113392399 0.28 ENST00000449572.2
ENST00000433505.1
RP11-426L16.8
RP11-426L16.8
chr2_+_102686820 0.28 ENST00000409929.1
ENST00000424272.1
IL1R1
interleukin 1 receptor, type I
chrX_-_100604184 0.28 ENST00000372902.3
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chrX_-_131352152 0.27 ENST00000342983.2
RAP2C
RAP2C, member of RAS oncogene family
chr13_-_76056250 0.27 ENST00000377636.3
ENST00000431480.2
ENST00000377625.2
ENST00000425511.1
TBC1D4
TBC1 domain family, member 4
chr11_+_34073195 0.26 ENST00000341394.4
CAPRIN1
cell cycle associated protein 1
chr22_-_44894178 0.26 ENST00000341255.3
LDOC1L
leucine zipper, down-regulated in cancer 1-like
chr12_-_8088773 0.26 ENST00000544291.1
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr7_-_51384451 0.25 ENST00000441453.1
ENST00000265136.7
ENST00000395542.2
ENST00000395540.2
COBL
cordon-bleu WH2 repeat protein
chrX_-_119249819 0.25 ENST00000217999.2
RHOXF1
Rhox homeobox family, member 1
chr15_+_77712993 0.25 ENST00000336216.4
ENST00000381714.3
ENST00000558651.1
HMG20A
high mobility group 20A
chr18_+_56531584 0.24 ENST00000590287.1
ZNF532
zinc finger protein 532
chr7_+_1022973 0.24 ENST00000340150.6
CYP2W1
cytochrome P450, family 2, subfamily W, polypeptide 1
chr19_-_44084586 0.24 ENST00000599693.1
ENST00000598165.1
XRCC1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr12_-_44152551 0.24 ENST00000416848.2
ENST00000550784.1
ENST00000547156.1
ENST00000549868.1
ENST00000553166.1
ENST00000551923.1
ENST00000431332.3
ENST00000344862.5
PUS7L
pseudouridylate synthase 7 homolog (S. cerevisiae)-like
chrX_-_14891150 0.24 ENST00000452869.1
ENST00000398334.1
ENST00000324138.3
FANCB
Fanconi anemia, complementation group B
chr3_+_141205852 0.24 ENST00000286364.3
ENST00000452898.1
RASA2
RAS p21 protein activator 2
chr7_+_152456904 0.24 ENST00000537264.1
ACTR3B
ARP3 actin-related protein 3 homolog B (yeast)
chr12_+_54447637 0.23 ENST00000609810.1
ENST00000430889.2
HOXC4
HOXC4
homeobox C4
Homeobox protein Hox-C4
chr19_+_41305740 0.23 ENST00000596517.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr8_+_144816303 0.22 ENST00000533004.1
FAM83H-AS1
FAM83H antisense RNA 1 (head to head)
chr2_+_28974531 0.22 ENST00000420282.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr7_+_1022811 0.21 ENST00000308919.7
CYP2W1
cytochrome P450, family 2, subfamily W, polypeptide 1
chr2_-_128432639 0.21 ENST00000545738.2
ENST00000355119.4
ENST00000409808.2
LIMS2
LIM and senescent cell antigen-like domains 2
chr19_+_41036371 0.21 ENST00000392023.1
SPTBN4
spectrin, beta, non-erythrocytic 4
chr7_+_152456829 0.21 ENST00000377776.3
ENST00000256001.8
ENST00000397282.2
ACTR3B
ARP3 actin-related protein 3 homolog B (yeast)
chr17_-_7082668 0.21 ENST00000573083.1
ENST00000574388.1
ASGR1
asialoglycoprotein receptor 1
chr19_-_30205963 0.21 ENST00000392278.2
C19orf12
chromosome 19 open reading frame 12
chr16_-_85146040 0.21 ENST00000539556.1
FAM92B
family with sequence similarity 92, member B
chr9_+_35906176 0.21 ENST00000354323.2
HRCT1
histidine rich carboxyl terminus 1
chr5_+_150591678 0.20 ENST00000523466.1
GM2A
GM2 ganglioside activator
chr6_-_86352982 0.20 ENST00000369622.3
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr11_-_8739383 0.20 ENST00000531060.1
ST5
suppression of tumorigenicity 5
chr5_+_175299743 0.20 ENST00000502265.1
CPLX2
complexin 2
chr16_+_58533951 0.20 ENST00000566192.1
ENST00000565088.1
ENST00000568640.1
ENST00000563978.1
ENST00000569923.1
ENST00000356752.4
ENST00000563799.1
ENST00000562999.1
ENST00000570248.1
ENST00000562731.1
ENST00000568424.1
NDRG4
NDRG family member 4
chrX_-_151938171 0.20 ENST00000393902.3
ENST00000417212.1
ENST00000370278.3
MAGEA3
melanoma antigen family A, 3
chr16_+_67143828 0.19 ENST00000563853.2
ENST00000569914.1
ENST00000569600.1
C16orf70
chromosome 16 open reading frame 70
chr12_-_7261772 0.19 ENST00000545280.1
ENST00000543933.1
ENST00000545337.1
ENST00000544702.1
ENST00000266542.4
C1RL
complement component 1, r subcomponent-like
chr8_+_90914859 0.19 ENST00000520659.1
OSGIN2
oxidative stress induced growth inhibitor family member 2
chr7_-_65113280 0.19 ENST00000593865.1
AC104057.1
Protein LOC100996407
chr3_-_48471454 0.19 ENST00000296440.6
ENST00000448774.2
PLXNB1
plexin B1
chr4_-_77996032 0.19 ENST00000505609.1
CCNI
cyclin I
chr12_-_56101647 0.19 ENST00000347027.6
ENST00000257879.6
ENST00000257880.7
ENST00000394230.2
ENST00000394229.2
ITGA7
integrin, alpha 7
chr12_+_123849462 0.18 ENST00000543072.1
hsa-mir-8072
hsa-mir-8072
chr14_+_57735614 0.18 ENST00000261558.3
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr13_-_77601282 0.18 ENST00000355619.5
FBXL3
F-box and leucine-rich repeat protein 3
chr19_-_42759300 0.18 ENST00000222329.4
ERF
Ets2 repressor factor
chr18_-_45456693 0.18 ENST00000587421.1
SMAD2
SMAD family member 2
chr2_+_128377550 0.18 ENST00000437387.1
ENST00000409090.1
MYO7B
myosin VIIB
chr19_+_41305627 0.17 ENST00000593525.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr8_-_22550815 0.17 ENST00000317216.2
EGR3
early growth response 3
chr12_-_48213735 0.17 ENST00000417902.1
ENST00000417107.1
HDAC7
histone deacetylase 7
chr2_+_219264762 0.17 ENST00000452977.1
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr17_+_15604513 0.17 ENST00000481540.1
ZNF286A
Homo sapiens zinc finger protein 286A (ZNF286A), transcript variant 6, mRNA.
chr11_-_118789613 0.17 ENST00000532899.1
BCL9L
B-cell CLL/lymphoma 9-like
chr17_-_73840614 0.17 ENST00000586108.1
UNC13D
unc-13 homolog D (C. elegans)
chr7_-_102257139 0.17 ENST00000521076.1
ENST00000462172.1
ENST00000522801.1
ENST00000449970.2
ENST00000262940.7
RASA4
RAS p21 protein activator 4
chr12_-_121973974 0.17 ENST00000538379.1
ENST00000541318.1
ENST00000541511.1
KDM2B
lysine (K)-specific demethylase 2B
chr12_-_12715266 0.16 ENST00000228862.2
DUSP16
dual specificity phosphatase 16
chr1_+_61548374 0.16 ENST00000485903.2
ENST00000371185.2
ENST00000371184.2
NFIA
nuclear factor I/A
chrX_+_149737046 0.16 ENST00000370396.2
ENST00000542741.1
ENST00000543350.1
ENST00000424519.1
ENST00000413012.2
MTM1
myotubularin 1
chr19_-_41220540 0.16 ENST00000594490.1
ADCK4
aarF domain containing kinase 4
chr1_+_61548225 0.16 ENST00000371187.3
NFIA
nuclear factor I/A
chr1_+_110091189 0.16 ENST00000369851.4
GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr11_-_17498348 0.16 ENST00000389817.3
ENST00000302539.4
ABCC8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr20_-_25062767 0.15 ENST00000429762.3
ENST00000444511.2
ENST00000376707.3
VSX1
visual system homeobox 1
chr12_+_118454500 0.15 ENST00000537315.1
ENST00000229043.3
ENST00000484086.2
ENST00000420967.1
ENST00000454402.2
ENST00000392542.2
ENST00000535092.1
RFC5
replication factor C (activator 1) 5, 36.5kDa
chr17_+_7788104 0.15 ENST00000380358.4
CHD3
chromodomain helicase DNA binding protein 3
chr9_-_14322319 0.15 ENST00000606230.1
NFIB
nuclear factor I/B
chr19_-_49140609 0.15 ENST00000601104.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr2_-_61765315 0.15 ENST00000406957.1
ENST00000401558.2
XPO1
exportin 1 (CRM1 homolog, yeast)
chr3_+_140660634 0.15 ENST00000446041.2
ENST00000507429.1
ENST00000324194.6
SLC25A36
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36
chr8_-_145578505 0.15 ENST00000526263.1
ENST00000398633.3
TMEM249
transmembrane protein 249
chr18_-_21242729 0.15 ENST00000585908.2
ANKRD29
ankyrin repeat domain 29
chr20_+_816695 0.14 ENST00000246100.3
FAM110A
family with sequence similarity 110, member A
chr17_+_1733276 0.14 ENST00000254719.5
RPA1
replication protein A1, 70kDa
chr10_+_17271266 0.14 ENST00000224237.5
VIM
vimentin
chr19_+_3366547 0.14 ENST00000341919.3
ENST00000590282.1
ENST00000443272.2
NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr8_+_90914757 0.14 ENST00000451899.2
OSGIN2
oxidative stress induced growth inhibitor family member 2
chr12_-_123849374 0.14 ENST00000602398.1
ENST00000602750.1
SBNO1
strawberry notch homolog 1 (Drosophila)
chr2_-_202508169 0.14 ENST00000409883.2
TMEM237
transmembrane protein 237
chr5_+_139505520 0.14 ENST00000333305.3
IGIP
IgA-inducing protein
chr2_-_179343226 0.14 ENST00000434643.2
FKBP7
FK506 binding protein 7
chr7_+_97840739 0.14 ENST00000609256.1
BHLHA15
basic helix-loop-helix family, member a15
chr16_-_1275257 0.14 ENST00000234798.4
TPSG1
tryptase gamma 1
chr9_-_13279563 0.14 ENST00000541718.1
MPDZ
multiple PDZ domain protein
chr4_+_56719782 0.14 ENST00000381295.2
ENST00000346134.7
ENST00000349598.6
EXOC1
exocyst complex component 1
chr12_+_49212514 0.14 ENST00000301050.2
ENST00000548279.1
ENST00000547230.1
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr17_-_73840415 0.13 ENST00000592386.1
ENST00000412096.2
ENST00000586147.1
UNC13D
unc-13 homolog D (C. elegans)
chr7_-_752074 0.13 ENST00000360274.4
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr10_-_103603523 0.13 ENST00000370046.1
KCNIP2
Kv channel interacting protein 2
chr19_+_41305330 0.13 ENST00000593972.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr10_+_13628921 0.13 ENST00000378572.3
PRPF18
pre-mRNA processing factor 18
chr4_+_190992087 0.13 ENST00000553598.1
DUX4L7
double homeobox 4 like 7
chr7_+_114562172 0.13 ENST00000393486.1
ENST00000257724.3
MDFIC
MyoD family inhibitor domain containing
chr19_-_3029011 0.12 ENST00000590536.1
ENST00000587137.1
ENST00000455444.2
ENST00000262953.6
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr9_+_84304628 0.12 ENST00000437181.1
RP11-154D17.1
RP11-154D17.1
chr16_-_28303360 0.12 ENST00000501520.1
RP11-57A19.2
RP11-57A19.2
chr20_-_58508359 0.12 ENST00000446834.1
SYCP2
synaptonemal complex protein 2
chr19_+_55999916 0.12 ENST00000587166.1
ENST00000389623.6
SSC5D
scavenger receptor cysteine rich domain containing (5 domains)
chr9_-_136933615 0.12 ENST00000371834.2
BRD3
bromodomain containing 3
chr20_+_62697564 0.12 ENST00000458442.1
TCEA2
transcription elongation factor A (SII), 2
chrX_+_17755563 0.12 ENST00000380045.3
ENST00000380041.3
ENST00000380043.3
ENST00000398080.1
SCML1
sex comb on midleg-like 1 (Drosophila)
chr13_+_60971427 0.12 ENST00000535286.1
ENST00000377881.2
TDRD3
tudor domain containing 3
chr11_-_6495082 0.12 ENST00000536344.1
TRIM3
tripartite motif containing 3
chr5_-_133512654 0.12 ENST00000522552.1
SKP1
S-phase kinase-associated protein 1
chr17_+_35849937 0.11 ENST00000394389.4
DUSP14
dual specificity phosphatase 14
chr11_-_57089774 0.11 ENST00000527207.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr1_+_164528866 0.11 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr12_+_44152740 0.11 ENST00000440781.2
ENST00000431837.1
ENST00000550616.1
ENST00000448290.2
ENST00000551736.1
IRAK4
interleukin-1 receptor-associated kinase 4
chr12_-_57522813 0.11 ENST00000556155.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr6_+_149638876 0.11 ENST00000392282.1
TAB2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr3_+_57094469 0.11 ENST00000334325.1
SPATA12
spermatogenesis associated 12
chr6_+_37321748 0.11 ENST00000373479.4
ENST00000394443.4
RNF8
ring finger protein 8, E3 ubiquitin protein ligase
chr12_+_861717 0.11 ENST00000535572.1
WNK1
WNK lysine deficient protein kinase 1
chr1_-_23857698 0.11 ENST00000361729.2
E2F2
E2F transcription factor 2
chr2_+_46926326 0.11 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr16_+_69958887 0.11 ENST00000568684.1
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr1_-_204380919 0.11 ENST00000367188.4
PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr11_-_57089671 0.11 ENST00000532437.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr16_+_30418910 0.11 ENST00000566625.1
ZNF771
zinc finger protein 771
chr17_+_55333876 0.11 ENST00000284073.2
MSI2
musashi RNA-binding protein 2
chr3_-_125094093 0.10 ENST00000484491.1
ENST00000492394.1
ENST00000471196.1
ENST00000468369.1
ENST00000544464.1
ENST00000485866.1
ENST00000360647.4
ZNF148
zinc finger protein 148
chr19_+_41305406 0.10 ENST00000406058.2
ENST00000593726.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chrX_+_47082408 0.10 ENST00000518022.1
ENST00000276052.6
CDK16
cyclin-dependent kinase 16
chr17_-_73840774 0.10 ENST00000207549.4
UNC13D
unc-13 homolog D (C. elegans)
chr17_+_38296576 0.10 ENST00000264645.7
CASC3
cancer susceptibility candidate 3
chr20_+_34700333 0.10 ENST00000441639.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr9_-_140335789 0.10 ENST00000344119.2
ENST00000371506.2
ENTPD8
ectonucleoside triphosphate diphosphohydrolase 8
chr11_-_8739566 0.10 ENST00000533020.1
ST5
suppression of tumorigenicity 5
chr12_+_62654119 0.10 ENST00000353364.3
ENST00000549523.1
ENST00000280377.5
USP15
ubiquitin specific peptidase 15
chr11_+_7506713 0.10 ENST00000329293.3
ENST00000534244.1
OLFML1
olfactomedin-like 1
chr14_+_100485712 0.10 ENST00000544450.2
EVL
Enah/Vasp-like
chr12_+_62654155 0.10 ENST00000312635.6
ENST00000393654.3
ENST00000549237.1
USP15
ubiquitin specific peptidase 15
chr19_-_18995029 0.10 ENST00000596048.1
CERS1
ceramide synthase 1
chr1_+_24104869 0.10 ENST00000246151.4
PITHD1
PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
chr10_-_103603568 0.10 ENST00000356640.2
KCNIP2
Kv channel interacting protein 2
chr20_+_57875658 0.10 ENST00000371025.3
EDN3
endothelin 3
chr16_-_4588762 0.09 ENST00000562334.1
ENST00000562579.1
ENST00000567695.1
ENST00000563507.1
CDIP1
cell death-inducing p53 target 1
chr3_-_49203744 0.09 ENST00000321895.6
CCDC71
coiled-coil domain containing 71
chr15_-_70390213 0.09 ENST00000557997.1
ENST00000317509.8
ENST00000442299.2
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr22_-_46450024 0.09 ENST00000396008.2
ENST00000333761.1
C22orf26
chromosome 22 open reading frame 26
chr13_+_24734880 0.09 ENST00000382095.4
SPATA13
spermatogenesis associated 13
chr8_-_144655141 0.09 ENST00000398882.3
MROH6
maestro heat-like repeat family member 6
chr2_-_46769694 0.09 ENST00000522587.1
ATP6V1E2
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
chr8_-_145331153 0.09 ENST00000377412.4
KM-PA-2
KM-PA-2 protein; Uncharacterized protein
chr1_-_228604454 0.09 ENST00000456946.2
TRIM17
tripartite motif containing 17
chr1_-_212004090 0.08 ENST00000366997.4
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr10_-_71930222 0.08 ENST00000458634.2
ENST00000373239.2
ENST00000373242.2
ENST00000373241.4
SAR1A
SAR1 homolog A (S. cerevisiae)
chr5_-_133512683 0.08 ENST00000353411.6
SKP1
S-phase kinase-associated protein 1
chr11_-_64703354 0.08 ENST00000532246.1
ENST00000279168.2
GPHA2
glycoprotein hormone alpha 2
chr2_-_37551846 0.08 ENST00000443187.1
PRKD3
protein kinase D3
chr9_-_13279589 0.08 ENST00000319217.7
MPDZ
multiple PDZ domain protein
chr5_+_169758393 0.08 ENST00000521471.1
ENST00000518357.1
ENST00000436248.3
CTB-114C7.3
CTB-114C7.3
chr1_-_150944411 0.08 ENST00000368949.4
CERS2
ceramide synthase 2
chr3_+_133524459 0.08 ENST00000484684.1
SRPRB
signal recognition particle receptor, B subunit
chr2_-_74570520 0.08 ENST00000394019.2
ENST00000346834.4
ENST00000359484.4
ENST00000423644.1
ENST00000377634.4
ENST00000436454.1
SLC4A5
solute carrier family 4 (sodium bicarbonate cotransporter), member 5
chr16_+_30969055 0.08 ENST00000452917.1
SETD1A
SET domain containing 1A
chr4_+_190992387 0.08 ENST00000554906.2
ENST00000553820.2
DUX4L7
double homeobox 4 like 7
chr11_-_61124266 0.08 ENST00000539890.1
CYB561A3
cytochrome b561 family, member A3
chr11_-_85779971 0.08 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chr17_-_1733114 0.08 ENST00000305513.7
SMYD4
SET and MYND domain containing 4
chrX_+_51636629 0.08 ENST00000375722.1
ENST00000326587.7
ENST00000375695.2
MAGED1
melanoma antigen family D, 1
chr18_+_9334755 0.08 ENST00000262120.5
TWSG1
twisted gastrulation BMP signaling modulator 1
chr12_+_57522692 0.08 ENST00000554174.1
LRP1
low density lipoprotein receptor-related protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of RREB1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.9 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.9 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.4 GO:0002432 granuloma formation(GO:0002432)
0.1 0.4 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.5 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.1 0.2 GO:1904875 regulation of DNA ligase activity(GO:1904875)
0.1 0.2 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.6 GO:0071484 cellular response to light intensity(GO:0071484)
0.1 0.3 GO:1904048 positive regulation of long term synaptic depression(GO:1900454) regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.1 0.8 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.2 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.5 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.3 GO:0001757 somite specification(GO:0001757)
0.1 0.3 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.4 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.5 GO:0043385 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.0 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.3 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.3 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.2 GO:0045208 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.8 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.2 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.0 0.2 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.3 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.1 GO:0072720 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.0 0.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.1 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.1 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.0 0.1 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 0.1 GO:0071048 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.4 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.5 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0014011 Schwann cell proliferation involved in axon regeneration(GO:0014011) negative regulation of Schwann cell migration(GO:1900148) regulation of Schwann cell proliferation involved in axon regeneration(GO:1905044) negative regulation of Schwann cell proliferation involved in axon regeneration(GO:1905045)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.2 GO:1904970 brush border assembly(GO:1904970)
0.0 0.1 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.2 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.2 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.3 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.0 0.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:1902363 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.0 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.0 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.1 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.1 GO:0045629 positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0072553 terminal button organization(GO:0072553)
0.0 0.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.3 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.5 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.2 GO:2001135 regulation of endocytic recycling(GO:2001135)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.2 0.6 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.2 0.8 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.4 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 0.6 GO:0097452 GAIT complex(GO:0097452)
0.1 0.5 GO:0070852 cell body fiber(GO:0070852)
0.1 0.2 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.3 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.2 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.8 GO:0031143 pseudopodium(GO:0031143)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.1 GO:0071020 post-spliceosomal complex(GO:0071020)
0.0 0.2 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0055028 cortical microtubule(GO:0055028)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.9 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0005642 annulate lamellae(GO:0005642)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.3 0.8 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.2 1.3 GO:0016936 galactoside binding(GO:0016936)
0.1 0.4 GO:0015039 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.1 1.0 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.9 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 0.4 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.5 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.3 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.6 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.2 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.3 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.6 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.0 0.5 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072) transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.6 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.0 GO:0032090 Pyrin domain binding(GO:0032090)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)
0.0 0.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.9 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 1.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.9 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.3 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.6 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.2 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation