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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for RUNX1_RUNX2

Z-value: 1.34

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Transcription factors associated with RUNX1_RUNX2

Gene Symbol Gene ID Gene Info
RUNX1
ENSG00000159216.14 RUNX family transcription factor 1
RUNX2
ENSG00000124813.16 RUNX family transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RUNX1hg19_v2_chr21_-_36262032_362620870.811.9e-01Click!
RUNX2hg19_v2_chr6_+_45296048_45296106-0.326.8e-01Click!

Activity profile of RUNX1_RUNX2 motif

Sorted Z-values of RUNX1_RUNX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_1606513 1.05 ENST00000382171.2
KRTAP5-1
keratin associated protein 5-1
chr4_+_89300158 0.64 ENST00000502870.1
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr8_-_102803163 0.62 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD
neurocalcin delta
chr6_-_34524049 0.57 ENST00000374037.3
SPDEF
SAM pointed domain containing ETS transcription factor
chr6_+_27925019 0.56 ENST00000244623.1
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr6_-_34524093 0.56 ENST00000544425.1
SPDEF
SAM pointed domain containing ETS transcription factor
chr12_-_58145889 0.50 ENST00000547853.1
CDK4
cyclin-dependent kinase 4
chr2_-_61389240 0.50 ENST00000606876.1
RP11-493E12.1
RP11-493E12.1
chr14_+_100531615 0.45 ENST00000392920.3
EVL
Enah/Vasp-like
chr11_+_86502085 0.42 ENST00000527521.1
PRSS23
protease, serine, 23
chr17_+_28443819 0.41 ENST00000479218.2
NSRP1
nuclear speckle splicing regulatory protein 1
chr9_-_116840728 0.39 ENST00000265132.3
AMBP
alpha-1-microglobulin/bikunin precursor
chr20_-_23967432 0.38 ENST00000286890.4
ENST00000278765.4
GGTLC1
gamma-glutamyltransferase light chain 1
chr14_+_74551650 0.37 ENST00000554938.1
LIN52
lin-52 homolog (C. elegans)
chr10_+_115312766 0.35 ENST00000351270.3
HABP2
hyaluronan binding protein 2
chr22_+_42665742 0.35 ENST00000332965.3
ENST00000415205.1
ENST00000446578.1
Z83851.3
Z83851.3
chr4_+_48807155 0.34 ENST00000504654.1
OCIAD1
OCIA domain containing 1
chr18_+_52385068 0.34 ENST00000586570.1
RAB27B
RAB27B, member RAS oncogene family
chr21_+_17909594 0.32 ENST00000441820.1
ENST00000602280.1
LINC00478
long intergenic non-protein coding RNA 478
chr9_+_131902346 0.32 ENST00000432124.1
ENST00000435305.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr15_+_49170083 0.32 ENST00000530028.2
EID1
EP300 interacting inhibitor of differentiation 1
chr11_+_826136 0.32 ENST00000528315.1
ENST00000533803.1
EFCAB4A
EF-hand calcium binding domain 4A
chr11_+_62475130 0.31 ENST00000294117.5
GNG3
guanine nucleotide binding protein (G protein), gamma 3
chr15_-_44069513 0.30 ENST00000433927.1
ELL3
elongation factor RNA polymerase II-like 3
chr6_-_31745037 0.30 ENST00000375688.4
VWA7
von Willebrand factor A domain containing 7
chr5_+_35856951 0.28 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R
interleukin 7 receptor
chr1_-_114414316 0.27 ENST00000528414.1
ENST00000538253.1
ENST00000460620.1
ENST00000420377.2
ENST00000525799.1
ENST00000359785.5
PTPN22
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr16_-_66952779 0.27 ENST00000570262.1
ENST00000394055.3
ENST00000299752.4
CDH16
cadherin 16, KSP-cadherin
chr11_+_115498761 0.27 ENST00000424313.2
AP000997.1
AP000997.1
chr19_-_52489923 0.26 ENST00000593596.1
ENST00000243644.4
ENST00000594929.1
ENST00000601430.1
ZNF350
zinc finger protein 350
chr3_+_186330712 0.26 ENST00000411641.2
ENST00000273784.5
AHSG
alpha-2-HS-glycoprotein
chr4_-_156297919 0.26 ENST00000450097.1
MAP9
microtubule-associated protein 9
chr16_-_66952742 0.26 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
CDH16
cadherin 16, KSP-cadherin
chr5_-_108063949 0.25 ENST00000606054.1
LINC01023
long intergenic non-protein coding RNA 1023
chr3_+_189507460 0.25 ENST00000434928.1
TP63
tumor protein p63
chr5_-_138725594 0.25 ENST00000302125.8
MZB1
marginal zone B and B1 cell-specific protein
chr14_-_94789663 0.25 ENST00000557225.1
ENST00000341584.3
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr6_-_31745085 0.24 ENST00000375686.3
ENST00000447450.1
VWA7
von Willebrand factor A domain containing 7
chr21_-_36421535 0.24 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
RUNX1
runt-related transcription factor 1
chr4_+_76481258 0.24 ENST00000311623.4
ENST00000435974.2
C4orf26
chromosome 4 open reading frame 26
chr11_+_6411670 0.24 ENST00000530395.1
ENST00000527275.1
SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr17_-_62009621 0.24 ENST00000349817.2
ENST00000392795.3
CD79B
CD79b molecule, immunoglobulin-associated beta
chr15_+_86098670 0.24 ENST00000558811.1
AKAP13
A kinase (PRKA) anchor protein 13
chr19_-_51875894 0.24 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
NKG7
natural killer cell group 7 sequence
chr20_-_25062767 0.23 ENST00000429762.3
ENST00000444511.2
ENST00000376707.3
VSX1
visual system homeobox 1
chr6_+_43968306 0.23 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223
chromosome 6 open reading frame 223
chr17_-_56494713 0.23 ENST00000407977.2
RNF43
ring finger protein 43
chr1_+_179050512 0.23 ENST00000367627.3
TOR3A
torsin family 3, member A
chr1_+_150954493 0.23 ENST00000368947.4
ANXA9
annexin A9
chr12_-_53594227 0.23 ENST00000550743.2
ITGB7
integrin, beta 7
chr11_+_1718425 0.23 ENST00000382160.1
KRTAP5-6
keratin associated protein 5-6
chr12_+_7072354 0.23 ENST00000537269.1
U47924.27
U47924.27
chr6_-_39399087 0.22 ENST00000229913.5
ENST00000541946.1
ENST00000394362.1
KIF6
kinesin family member 6
chr17_-_56494908 0.22 ENST00000577716.1
RNF43
ring finger protein 43
chr7_-_7782204 0.22 ENST00000418534.2
AC007161.5
AC007161.5
chr12_+_54384370 0.22 ENST00000504315.1
HOXC6
homeobox C6
chr14_+_39944025 0.22 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
RP11-111A21.1
chr14_+_64680854 0.22 ENST00000458046.2
SYNE2
spectrin repeat containing, nuclear envelope 2
chr11_-_64013663 0.22 ENST00000392210.2
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr16_-_57513657 0.22 ENST00000566936.1
ENST00000568617.1
ENST00000567276.1
ENST00000569548.1
ENST00000569250.1
ENST00000564378.1
DOK4
docking protein 4
chr16_-_85969774 0.21 ENST00000598933.1
RP11-542M13.3
RP11-542M13.3
chr17_-_46115122 0.21 ENST00000006101.4
COPZ2
coatomer protein complex, subunit zeta 2
chr1_+_152486950 0.21 ENST00000368790.3
CRCT1
cysteine-rich C-terminal 1
chr17_+_73629500 0.21 ENST00000375215.3
SMIM5
small integral membrane protein 5
chr20_+_31870927 0.20 ENST00000253354.1
BPIFB1
BPI fold containing family B, member 1
chr1_+_179051160 0.20 ENST00000367625.4
ENST00000352445.6
TOR3A
torsin family 3, member A
chr14_+_100531738 0.20 ENST00000555706.1
EVL
Enah/Vasp-like
chr17_+_70036164 0.20 ENST00000602013.1
AC007461.1
Uncharacterized protein
chr10_+_89124746 0.20 ENST00000465545.1
NUTM2D
NUT family member 2D
chr1_-_1891537 0.20 ENST00000493316.1
ENST00000461752.2
C1orf222
chromosome 1 open reading frame 222
chr3_+_189507523 0.20 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
TP63
tumor protein p63
chr21_-_36421626 0.20 ENST00000300305.3
RUNX1
runt-related transcription factor 1
chr12_-_49581152 0.20 ENST00000550811.1
TUBA1A
tubulin, alpha 1a
chr11_-_87908600 0.19 ENST00000531138.1
ENST00000526372.1
ENST00000243662.6
RAB38
RAB38, member RAS oncogene family
chr7_+_139025875 0.19 ENST00000297534.6
C7orf55
chromosome 7 open reading frame 55
chr6_-_30709980 0.19 ENST00000416018.1
ENST00000445853.1
ENST00000413165.1
ENST00000418160.1
FLOT1
flotillin 1
chr2_+_26785409 0.19 ENST00000329615.3
ENST00000409392.1
C2orf70
chromosome 2 open reading frame 70
chr11_+_6411636 0.19 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr5_-_138725560 0.19 ENST00000412103.2
ENST00000457570.2
MZB1
marginal zone B and B1 cell-specific protein
chr19_-_36233332 0.19 ENST00000592537.1
ENST00000246532.1
ENST00000344990.3
ENST00000588992.1
IGFLR1
IGF-like family receptor 1
chr7_+_45067265 0.19 ENST00000474617.1
CCM2
cerebral cavernous malformation 2
chr14_+_105212297 0.19 ENST00000556623.1
ENST00000555674.1
ADSSL1
adenylosuccinate synthase like 1
chr20_+_44637526 0.18 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr20_+_55108302 0.18 ENST00000371325.1
FAM209B
family with sequence similarity 209, member B
chr17_+_2264983 0.18 ENST00000574650.1
SGSM2
small G protein signaling modulator 2
chr15_+_49170281 0.18 ENST00000560490.1
EID1
EP300 interacting inhibitor of differentiation 1
chr17_+_73780852 0.18 ENST00000589666.1
UNK
unkempt family zinc finger
chr15_-_37393406 0.18 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr17_-_56494882 0.18 ENST00000584437.1
RNF43
ring finger protein 43
chr15_+_31508174 0.18 ENST00000559292.2
ENST00000557928.1
RP11-16E12.1
RP11-16E12.1
chr11_-_6462210 0.18 ENST00000265983.3
HPX
hemopexin
chr3_+_189507432 0.18 ENST00000354600.5
TP63
tumor protein p63
chr11_-_58345569 0.18 ENST00000528954.1
ENST00000528489.1
LPXN
leupaxin
chr11_-_117699413 0.18 ENST00000528014.1
FXYD2
FXYD domain containing ion transport regulator 2
chr12_-_58027138 0.18 ENST00000341156.4
B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr5_+_39520499 0.18 ENST00000604954.1
CTD-2078B5.2
CTD-2078B5.2
chr4_+_178230985 0.18 ENST00000264596.3
NEIL3
nei endonuclease VIII-like 3 (E. coli)
chr1_+_145726886 0.18 ENST00000443667.1
PDZK1
PDZ domain containing 1
chr22_+_22988816 0.17 ENST00000480559.1
ENST00000448514.1
GGTLC2
gamma-glutamyltransferase light chain 2
chr17_+_73539232 0.17 ENST00000580925.1
LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr1_-_21948906 0.17 ENST00000374761.2
ENST00000599760.1
RAP1GAP
RAP1 GTPase activating protein
chr9_-_133769225 0.17 ENST00000343079.1
QRFP
pyroglutamylated RFamide peptide
chr16_+_28875126 0.17 ENST00000359285.5
ENST00000538342.1
SH2B1
SH2B adaptor protein 1
chr7_+_76054224 0.17 ENST00000394857.3
ZP3
zona pellucida glycoprotein 3 (sperm receptor)
chrX_-_30327495 0.17 ENST00000453287.1
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr1_+_17866290 0.17 ENST00000361221.3
ENST00000452522.1
ENST00000434513.1
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr15_+_73976545 0.17 ENST00000318443.5
ENST00000537340.2
ENST00000318424.5
CD276
CD276 molecule
chr2_-_20212422 0.16 ENST00000421259.2
ENST00000407540.3
MATN3
matrilin 3
chr2_+_128175997 0.16 ENST00000234071.3
ENST00000429925.1
ENST00000442644.1
ENST00000453608.2
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr17_+_78193443 0.16 ENST00000577155.1
SLC26A11
solute carrier family 26 (anion exchanger), member 11
chr12_-_49333446 0.16 ENST00000537495.1
AC073610.5
Uncharacterized protein
chr17_-_43025005 0.16 ENST00000587309.1
ENST00000593135.1
ENST00000339151.4
KIF18B
kinesin family member 18B
chr22_+_47016277 0.16 ENST00000406902.1
GRAMD4
GRAM domain containing 4
chr9_-_35079911 0.15 ENST00000448890.1
FANCG
Fanconi anemia, complementation group G
chr14_+_77244349 0.15 ENST00000554743.1
VASH1
vasohibin 1
chr16_+_28875268 0.15 ENST00000395532.4
SH2B1
SH2B adaptor protein 1
chr11_+_102552041 0.15 ENST00000537079.1
RP11-817J15.3
Uncharacterized protein
chr9_-_130635741 0.15 ENST00000223836.10
AK1
adenylate kinase 1
chr1_+_221051699 0.15 ENST00000366903.6
HLX
H2.0-like homeobox
chr16_-_70712229 0.15 ENST00000562883.2
MTSS1L
metastasis suppressor 1-like
chr16_-_28608424 0.15 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr1_-_153517473 0.15 ENST00000368715.1
S100A4
S100 calcium binding protein A4
chr6_+_31515337 0.15 ENST00000376148.4
ENST00000376145.4
NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr22_-_21580582 0.15 ENST00000424627.1
GGT2
gamma-glutamyltransferase 2
chr3_+_57541975 0.14 ENST00000487257.1
ENST00000311180.8
PDE12
phosphodiesterase 12
chr6_+_31514622 0.14 ENST00000376146.4
NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr6_-_107235287 0.14 ENST00000436659.1
ENST00000428750.1
ENST00000427903.1
RP1-60O19.1
RP1-60O19.1
chr3_-_187454281 0.14 ENST00000232014.4
BCL6
B-cell CLL/lymphoma 6
chrX_-_51239425 0.14 ENST00000375992.3
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr12_+_65996599 0.14 ENST00000539116.1
ENST00000541391.1
RP11-221N13.3
RP11-221N13.3
chr17_-_19265982 0.14 ENST00000268841.6
ENST00000261499.4
ENST00000575478.1
B9D1
B9 protein domain 1
chr1_+_156211753 0.14 ENST00000368272.4
BGLAP
bone gamma-carboxyglutamate (gla) protein
chr12_-_58027002 0.14 ENST00000449184.3
B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr2_-_242211359 0.14 ENST00000444092.1
HDLBP
high density lipoprotein binding protein
chr1_+_1217305 0.14 ENST00000470022.1
SCNN1D
sodium channel, non-voltage-gated 1, delta subunit
chr10_+_99205959 0.14 ENST00000352634.4
ENST00000353979.3
ENST00000370842.2
ENST00000345745.5
ZDHHC16
zinc finger, DHHC-type containing 16
chr1_+_159272111 0.14 ENST00000368114.1
FCER1A
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
chr17_+_50939459 0.14 ENST00000412360.1
AC102948.2
Uncharacterized protein
chr6_+_13272904 0.14 ENST00000379335.3
ENST00000379329.1
PHACTR1
phosphatase and actin regulator 1
chr15_-_65117807 0.14 ENST00000559239.1
ENST00000268043.4
ENST00000333425.6
PIF1
PIF1 5'-to-3' DNA helicase
chr3_+_187957646 0.14 ENST00000457242.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr1_+_174843548 0.14 ENST00000478442.1
ENST00000465412.1
RABGAP1L
RAB GTPase activating protein 1-like
chrX_-_54209640 0.14 ENST00000375180.2
ENST00000328235.4
ENST00000477084.1
FAM120C
family with sequence similarity 120C
chr22_+_24105394 0.14 ENST00000305199.5
ENST00000382821.3
C22orf15
chromosome 22 open reading frame 15
chr8_-_25281747 0.13 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr22_-_42342692 0.13 ENST00000404067.1
ENST00000402338.1
CENPM
centromere protein M
chr13_-_43566301 0.13 ENST00000398762.3
ENST00000313640.7
ENST00000313624.7
EPSTI1
epithelial stromal interaction 1 (breast)
chr10_+_96698406 0.13 ENST00000260682.6
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9
chrX_+_22056165 0.13 ENST00000535894.1
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr16_+_89686991 0.13 ENST00000393092.3
DPEP1
dipeptidase 1 (renal)
chr16_-_10788770 0.13 ENST00000283025.2
TEKT5
tektin 5
chr19_-_55836697 0.13 ENST00000438693.1
ENST00000591570.1
TMEM150B
transmembrane protein 150B
chr1_+_11333546 0.13 ENST00000376804.2
UBIAD1
UbiA prenyltransferase domain containing 1
chr2_-_217560248 0.13 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr16_-_28608364 0.13 ENST00000533150.1
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr5_+_138611798 0.13 ENST00000502394.1
MATR3
matrin 3
chr17_-_79008373 0.13 ENST00000577066.1
ENST00000573167.1
BAIAP2-AS1
BAIAP2 antisense RNA 1 (head to head)
chr14_-_81425828 0.13 ENST00000555529.1
ENST00000556042.1
ENST00000556981.1
CEP128
centrosomal protein 128kDa
chr19_-_55836669 0.13 ENST00000326652.4
TMEM150B
transmembrane protein 150B
chr11_-_67141090 0.13 ENST00000312438.7
CLCF1
cardiotrophin-like cytokine factor 1
chr16_+_29674540 0.13 ENST00000436527.1
ENST00000360121.3
ENST00000449759.1
SPN
QPRT
sialophorin
quinolinate phosphoribosyltransferase
chr19_-_49567124 0.13 ENST00000301411.3
NTF4
neurotrophin 4
chr3_-_52188397 0.13 ENST00000474012.1
ENST00000296484.2
POC1A
POC1 centriolar protein A
chr17_-_42031300 0.13 ENST00000592796.1
PYY
peptide YY
chr22_-_30661807 0.13 ENST00000403389.1
OSM
oncostatin M
chr17_-_37309480 0.13 ENST00000539608.1
PLXDC1
plexin domain containing 1
chr5_-_137071756 0.13 ENST00000394937.3
ENST00000309755.4
KLHL3
kelch-like family member 3
chr21_+_35107346 0.13 ENST00000456489.1
ITSN1
intersectin 1 (SH3 domain protein)
chr1_+_154966058 0.13 ENST00000392487.1
LENEP
lens epithelial protein
chr1_-_150978953 0.13 ENST00000493834.2
FAM63A
family with sequence similarity 63, member A
chr6_-_30710447 0.13 ENST00000456573.2
FLOT1
flotillin 1
chr3_+_187461442 0.13 ENST00000450760.1
RP11-211G3.2
RP11-211G3.2
chrX_+_119005399 0.13 ENST00000371437.4
NDUFA1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
chr15_+_84116106 0.13 ENST00000535412.1
ENST00000324537.5
SH3GL3
SH3-domain GRB2-like 3
chr8_+_145162629 0.13 ENST00000323662.8
KIAA1875
KIAA1875
chr17_+_34087888 0.13 ENST00000586491.1
ENST00000588628.1
ENST00000285023.4
C17orf50
chromosome 17 open reading frame 50
chr10_+_99332198 0.13 ENST00000307518.5
ENST00000298808.5
ENST00000370655.1
ANKRD2
ankyrin repeat domain 2 (stretch responsive muscle)
chr1_+_196621156 0.13 ENST00000359637.2
CFH
complement factor H
chr2_+_38177575 0.13 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
RMDN2
regulator of microtubule dynamics 2
chr11_-_65548265 0.12 ENST00000532090.2
AP5B1
adaptor-related protein complex 5, beta 1 subunit
chr11_-_75062829 0.12 ENST00000393505.4
ARRB1
arrestin, beta 1
chr17_+_41994576 0.12 ENST00000588043.2
FAM215A
family with sequence similarity 215, member A (non-protein coding)
chr1_-_204165610 0.12 ENST00000367194.4
KISS1
KiSS-1 metastasis-suppressor
chr1_+_24018269 0.12 ENST00000374550.3
RPL11
ribosomal protein L11
chr20_+_32782375 0.12 ENST00000568305.1
ASIP
agouti signaling protein
chr17_+_73996987 0.12 ENST00000588812.1
ENST00000448471.1
CDK3
cyclin-dependent kinase 3
chr6_+_147981838 0.12 ENST00000427015.1
ENST00000432506.1
RP11-307P5.1
RP11-307P5.1
chr13_+_113622810 0.12 ENST00000397030.1
MCF2L
MCF.2 cell line derived transforming sequence-like
chr12_+_57828521 0.12 ENST00000309668.2
INHBC
inhibin, beta C
chr22_+_39378375 0.12 ENST00000402182.3
ENST00000333467.3
APOBEC3B
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
chr4_-_84035868 0.12 ENST00000426923.2
ENST00000509973.1
PLAC8
placenta-specific 8
chr12_-_10601963 0.12 ENST00000543893.1
KLRC1
killer cell lectin-like receptor subfamily C, member 1
chr10_-_135150367 0.12 ENST00000368555.3
ENST00000252939.4
ENST00000368558.1
ENST00000368556.2
CALY
calcyon neuron-specific vesicular protein
chr16_+_85942594 0.12 ENST00000566369.1
IRF8
interferon regulatory factor 8
chr2_+_149402009 0.12 ENST00000457184.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr11_-_75062730 0.12 ENST00000420843.2
ENST00000360025.3
ARRB1
arrestin, beta 1
chr3_-_182703688 0.12 ENST00000466812.1
ENST00000487822.1
ENST00000460412.1
ENST00000469954.1
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1
chr15_-_56757329 0.12 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr9_+_139839711 0.12 ENST00000224181.3
C8G
complement component 8, gamma polypeptide
chr8_-_103136481 0.12 ENST00000524209.1
ENST00000517822.1
ENST00000523923.1
ENST00000521599.1
ENST00000521964.1
ENST00000311028.3
ENST00000518166.1
NCALD
neurocalcin delta

Network of associatons between targets according to the STRING database.

First level regulatory network of RUNX1_RUNX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 1.0 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.1 0.6 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.3 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 0.5 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.1 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.6 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.1 0.3 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.1 0.5 GO:0023021 termination of signal transduction(GO:0023021)
0.1 0.2 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.1 0.4 GO:0071543 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 0.2 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.1 0.2 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1 0.2 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.3 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.4 GO:0032226 positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.0 0.2 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.5 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0043605 antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605)
0.0 0.1 GO:0061193 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.0 0.6 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.3 GO:0046618 drug export(GO:0046618)
0.0 0.2 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.2 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.0 0.3 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.2 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.2 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.2 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.1 GO:0097195 pilomotor reflex(GO:0097195)
0.0 0.4 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.7 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.1 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.3 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:1904604 regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
0.0 0.4 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0014734 skeletal muscle hypertrophy(GO:0014734) regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.0 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.1 GO:0045399 positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.1 GO:1904106 protein localization to microvillus(GO:1904106)
0.0 0.1 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0003095 pressure natriuresis(GO:0003095)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.0 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.0 0.1 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.1 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.0 0.2 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.1 GO:0060455 negative regulation of gastric acid secretion(GO:0060455) positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.0 0.1 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.0 0.1 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.1 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.2 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.1 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.0 0.1 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.1 GO:0009233 menaquinone metabolic process(GO:0009233)
0.0 0.1 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.2 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 0.3 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.2 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.1 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.1 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.0 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0 0.1 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
0.0 0.1 GO:1904970 brush border assembly(GO:1904970)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.1 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.2 GO:0048289 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293) positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.2 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:1905007 positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905007)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.0 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.0 0.1 GO:0019075 virus maturation(GO:0019075)
0.0 0.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.1 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.1 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.0 0.1 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.1 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.4 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.1 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.2 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.1 GO:0042412 taurine biosynthetic process(GO:0042412)
0.0 0.3 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644) necroptotic signaling pathway(GO:0097527)
0.0 0.1 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.0 0.2 GO:0070269 pyroptosis(GO:0070269)
0.0 0.0 GO:0035696 monocyte extravasation(GO:0035696) regulation of fertilization(GO:0080154) activation of meiosis(GO:0090427) regulation of monocyte extravasation(GO:2000437)
0.0 0.1 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.0 0.0 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.1 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.0 GO:1904172 regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.0 0.0 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.0 GO:0003284 septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289)
0.0 0.1 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.1 GO:0071926 endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.1 GO:1990523 bone regeneration(GO:1990523)
0.0 0.2 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.0 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.0 GO:0060214 endocardium formation(GO:0060214)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.1 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.0 0.2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.2 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.0 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.0 0.0 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.0 0.1 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.1 GO:0014738 regulation of muscle hyperplasia(GO:0014738) negative regulation of muscle hyperplasia(GO:0014740)
0.0 0.0 GO:0002290 gamma-delta T cell activation involved in immune response(GO:0002290) Fc receptor mediated inhibitory signaling pathway(GO:0002774) negative regulation of interferon-beta secretion(GO:0035548) negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.0 0.0 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.0 0.0 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.0 0.0 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.0 0.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.0 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.1 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.0 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.2 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.2 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0032490 detection of molecule of bacterial origin(GO:0032490)
0.0 0.0 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:0001889 liver development(GO:0001889) hepaticobiliary system development(GO:0061008)
0.0 0.1 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.0 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.0 0.1 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.0 0.0 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.0 0.0 GO:2000677 regulation of transcription regulatory region DNA binding(GO:2000677)
0.0 0.1 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.1 GO:0090166 histone H3-S10 phosphorylation(GO:0043987) Golgi disassembly(GO:0090166)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.1 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.0 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.0 GO:0001897 cytolysis by symbiont of host cells(GO:0001897)
0.0 0.0 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.0 GO:0009624 response to nematode(GO:0009624)
0.0 0.1 GO:0030238 male sex determination(GO:0030238)
0.0 0.0 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.2 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 0.0 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.0 GO:0006173 dADP biosynthetic process(GO:0006173)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.1 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.1 GO:0043473 pigmentation(GO:0043473)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.0 GO:0072249 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.0 GO:0002432 granuloma formation(GO:0002432)
0.0 0.1 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.0 GO:0046471 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.0 GO:1903365 regulation of fear response(GO:1903365) regulation of behavioral fear response(GO:2000822)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.2 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.7 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.2 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.2 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.2 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:0042022 interleukin-12 receptor complex(GO:0042022)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 1.8 GO:0045095 keratin filament(GO:0045095)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.6 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:1990423 RZZ complex(GO:1990423)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.3 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.3 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.3 GO:0042627 chylomicron(GO:0042627)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.4 GO:0042599 lamellar body(GO:0042599)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.0 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0071020 post-spliceosomal complex(GO:0071020)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.0 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.2 GO:0072559 NLRP3 inflammasome complex(GO:0072559)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.1 0.3 GO:0019862 IgA binding(GO:0019862)
0.1 0.2 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.4 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.2 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.4 GO:0052842 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.2 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 0.3 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.7 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.0 0.2 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.2 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0016517 interleukin-12 receptor activity(GO:0016517)
0.0 0.7 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.2 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.1 GO:1904599 advanced glycation end-product binding(GO:1904599)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0031782 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.6 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.1 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.1 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) thyroid hormone receptor activity(GO:0004887) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.0 GO:0045118 azole transporter activity(GO:0045118)
0.0 0.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.2 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.1 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 0.3 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.9 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.0 GO:0030984 kininogen binding(GO:0030984)
0.0 0.0 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.0 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.0 0.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.1 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0001602 peptide YY receptor activity(GO:0001601) pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.2 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.1 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.0 GO:0032396 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107) HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) inhibitory MHC class I receptor activity(GO:0032396)
0.0 0.0 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.1 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.5 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.0 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.0 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.0 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.0 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.0 GO:0019808 polyamine binding(GO:0019808)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.0 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0001851 complement component C3b binding(GO:0001851)
0.0 0.0 GO:0070984 SET domain binding(GO:0070984)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.0 ST ADRENERGIC Adrenergic Pathway
0.0 1.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.0 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway