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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for SHOX2_HOXC5

Z-value: 0.74

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Transcription factors associated with SHOX2_HOXC5

Gene Symbol Gene ID Gene Info
SHOX2
ENSG00000168779.15 short stature homeobox 2
HOXC5
ENSG00000172789.3 homeobox C5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SHOX2hg19_v2_chr3_-_157824292_1578243340.613.9e-01Click!
HOXC5hg19_v2_chr12_+_54426637_54426637-0.109.0e-01Click!

Activity profile of SHOX2_HOXC5 motif

Sorted Z-values of SHOX2_HOXC5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_139763521 0.68 ENST00000263549.3
PARP12
poly (ADP-ribose) polymerase family, member 12
chr22_-_32766972 0.57 ENST00000382084.4
ENST00000382086.2
RFPL3S
RFPL3 antisense
chr11_+_5710919 0.56 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr11_+_5712234 0.51 ENST00000414641.1
TRIM22
tripartite motif containing 22
chr5_+_53686658 0.47 ENST00000512618.1
LINC01033
long intergenic non-protein coding RNA 1033
chr19_-_3557570 0.44 ENST00000355415.2
MFSD12
major facilitator superfamily domain containing 12
chr11_-_33913708 0.43 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr12_-_25150373 0.42 ENST00000549828.1
C12orf77
chromosome 12 open reading frame 77
chr11_-_121986923 0.42 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr10_+_90562705 0.41 ENST00000539337.1
LIPM
lipase, family member M
chr2_-_158345341 0.40 ENST00000435117.1
CYTIP
cytohesin 1 interacting protein
chr4_-_19458597 0.40 ENST00000505347.1
RP11-3J1.1
RP11-3J1.1
chr5_-_119669160 0.39 ENST00000514240.1
CTC-552D5.1
CTC-552D5.1
chr7_+_37723336 0.38 ENST00000450180.1
GPR141
G protein-coupled receptor 141
chr11_-_327537 0.35 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr12_+_34175398 0.35 ENST00000538927.1
ALG10
ALG10, alpha-1,2-glucosyltransferase
chr14_-_67878917 0.33 ENST00000216446.4
PLEK2
pleckstrin 2
chr2_-_87248975 0.33 ENST00000409310.2
ENST00000355705.3
PLGLB1
plasminogen-like B1
chr14_-_73997901 0.33 ENST00000557603.1
ENST00000556455.1
HEATR4
HEAT repeat containing 4
chr11_-_321050 0.32 ENST00000399808.4
IFITM3
interferon induced transmembrane protein 3
chr11_-_104817919 0.32 ENST00000533252.1
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr2_+_182850551 0.31 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr6_+_24126350 0.31 ENST00000378491.4
ENST00000378478.1
ENST00000378477.2
NRSN1
neurensin 1
chr7_-_105926058 0.31 ENST00000417537.1
NAMPT
nicotinamide phosphoribosyltransferase
chr10_+_91152303 0.29 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr11_-_104972158 0.28 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr15_+_62853562 0.28 ENST00000561311.1
TLN2
talin 2
chr8_+_39972170 0.28 ENST00000521257.1
RP11-359E19.2
RP11-359E19.2
chr18_-_51750948 0.28 ENST00000583046.1
ENST00000398398.2
MBD2
methyl-CpG binding domain protein 2
chr2_-_70352421 0.27 ENST00000414141.1
AC016700.5
AC016700.5
chr5_-_55412774 0.27 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chrM_+_10758 0.27 ENST00000361381.2
MT-ND4
mitochondrially encoded NADH dehydrogenase 4
chr1_+_28199047 0.26 ENST00000373925.1
ENST00000328928.7
ENST00000373927.3
ENST00000427466.1
ENST00000442118.1
ENST00000373921.3
THEMIS2
thymocyte selection associated family member 2
chr4_+_75174180 0.26 ENST00000413830.1
EPGN
epithelial mitogen
chr9_-_100684845 0.26 ENST00000375119.3
C9orf156
chromosome 9 open reading frame 156
chr11_-_104905840 0.25 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr6_-_27835357 0.25 ENST00000331442.3
HIST1H1B
histone cluster 1, H1b
chr10_-_13043697 0.25 ENST00000378825.3
CCDC3
coiled-coil domain containing 3
chr1_+_20878932 0.25 ENST00000332947.4
FAM43B
family with sequence similarity 43, member B
chr22_-_32767017 0.25 ENST00000400234.1
RFPL3S
RFPL3 antisense
chr4_-_110736505 0.24 ENST00000609440.1
RP11-602N24.3
RP11-602N24.3
chr1_+_151253991 0.24 ENST00000443959.1
ZNF687
zinc finger protein 687
chr12_+_26348246 0.24 ENST00000422622.2
SSPN
sarcospan
chr16_+_14802801 0.24 ENST00000526520.1
ENST00000531598.2
NPIPA3
nuclear pore complex interacting protein family, member A3
chr5_-_126409159 0.23 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
C5orf63
chromosome 5 open reading frame 63
chr1_+_225600404 0.23 ENST00000366845.2
AC092811.1
AC092811.1
chr11_-_58611957 0.23 ENST00000532258.1
GLYATL2
glycine-N-acyltransferase-like 2
chr3_+_136676851 0.23 ENST00000309741.5
IL20RB
interleukin 20 receptor beta
chr2_-_228497888 0.23 ENST00000264387.4
ENST00000409066.1
C2orf83
chromosome 2 open reading frame 83
chr1_-_6420737 0.23 ENST00000541130.1
ENST00000377845.3
ACOT7
acyl-CoA thioesterase 7
chr21_-_22175341 0.23 ENST00000416768.1
ENST00000452561.1
ENST00000419299.1
ENST00000437238.1
LINC00320
long intergenic non-protein coding RNA 320
chr18_+_52385068 0.23 ENST00000586570.1
RAB27B
RAB27B, member RAS oncogene family
chr22_+_39966758 0.22 ENST00000407673.1
ENST00000401624.1
ENST00000404898.1
ENST00000402142.3
ENST00000336649.4
ENST00000400164.3
CACNA1I
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr17_-_72772425 0.22 ENST00000578822.1
NAT9
N-acetyltransferase 9 (GCN5-related, putative)
chr14_+_94577074 0.22 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
IFI27
interferon, alpha-inducible protein 27
chr1_-_201140673 0.22 ENST00000367333.2
TMEM9
transmembrane protein 9
chr22_+_50981079 0.22 ENST00000609268.1
CTA-384D8.34
CTA-384D8.34
chr4_+_75174204 0.22 ENST00000332112.4
ENST00000514968.1
ENST00000503098.1
ENST00000502358.1
ENST00000509145.1
ENST00000505212.1
EPGN
epithelial mitogen
chr7_-_92777606 0.21 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr1_-_204135450 0.21 ENST00000272190.8
ENST00000367195.2
REN
renin
chr11_-_104916034 0.21 ENST00000528513.1
ENST00000375706.2
ENST00000375704.3
CARD16
caspase recruitment domain family, member 16
chr2_+_228736335 0.21 ENST00000440997.1
ENST00000545118.1
DAW1
dynein assembly factor with WDR repeat domains 1
chr7_-_149158187 0.21 ENST00000247930.4
ZNF777
zinc finger protein 777
chr10_+_6779326 0.20 ENST00000417112.1
RP11-554I8.2
RP11-554I8.2
chr1_-_190446759 0.20 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr20_-_33735070 0.20 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr7_-_150020578 0.20 ENST00000478393.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr17_-_42992856 0.20 ENST00000588316.1
ENST00000435360.2
ENST00000586793.1
ENST00000588735.1
ENST00000588037.1
ENST00000592320.1
ENST00000253408.5
GFAP
glial fibrillary acidic protein
chr14_-_77542485 0.20 ENST00000556781.1
ENST00000557526.1
ENST00000555512.1
RP11-7F17.3
RP11-7F17.3
chr5_-_177207634 0.20 ENST00000513554.1
ENST00000440605.3
FAM153A
family with sequence similarity 153, member A
chr22_+_18632666 0.19 ENST00000215794.7
USP18
ubiquitin specific peptidase 18
chr14_+_32798462 0.19 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr16_-_66584059 0.19 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
TK2
thymidine kinase 2, mitochondrial
chr14_+_35591928 0.19 ENST00000605870.1
ENST00000557404.3
KIAA0391
KIAA0391
chr10_+_35484793 0.19 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr2_+_232316906 0.19 ENST00000370380.2
AC017104.2
Uncharacterized protein
chr1_-_183559693 0.19 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
NCF2
neutrophil cytosolic factor 2
chr2_+_219110149 0.19 ENST00000456575.1
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr11_-_102668879 0.19 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr6_+_55192267 0.19 ENST00000340465.2
GFRAL
GDNF family receptor alpha like
chr21_-_19858196 0.19 ENST00000422787.1
TMPRSS15
transmembrane protease, serine 15
chr6_-_133035185 0.19 ENST00000367928.4
VNN1
vanin 1
chr22_+_46476192 0.19 ENST00000443490.1
FLJ27365
hsa-mir-4763
chr3_-_151047327 0.18 ENST00000325602.5
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr19_+_54466179 0.18 ENST00000270458.2
CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr17_+_7155819 0.18 ENST00000570322.1
ENST00000576496.1
ENST00000574841.2
ELP5
elongator acetyltransferase complex subunit 5
chr14_-_46185155 0.18 ENST00000555442.1
RP11-369C8.1
RP11-369C8.1
chr21_+_33671160 0.18 ENST00000303645.5
MRAP
melanocortin 2 receptor accessory protein
chr7_-_6570817 0.18 ENST00000435185.1
GRID2IP
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein
chr17_-_72772462 0.18 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
NAT9
N-acetyltransferase 9 (GCN5-related, putative)
chr15_-_75248954 0.18 ENST00000499788.2
RPP25
ribonuclease P/MRP 25kDa subunit
chr2_+_234826016 0.17 ENST00000324695.4
ENST00000433712.2
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr11_-_74800799 0.17 ENST00000305159.3
OR2AT4
olfactory receptor, family 2, subfamily AT, member 4
chr16_-_29934558 0.17 ENST00000568995.1
ENST00000566413.1
KCTD13
potassium channel tetramerization domain containing 13
chr11_-_104827425 0.17 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr8_+_39770803 0.17 ENST00000518237.1
IDO1
indoleamine 2,3-dioxygenase 1
chr7_-_22862406 0.17 ENST00000372879.4
TOMM7
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr5_-_173217931 0.17 ENST00000522731.1
CTB-43E15.4
CTB-43E15.4
chr15_-_78913628 0.17 ENST00000348639.3
CHRNA3
cholinergic receptor, nicotinic, alpha 3 (neuronal)
chr20_-_48747662 0.17 ENST00000371656.2
TMEM189
transmembrane protein 189
chr1_-_33430286 0.17 ENST00000373456.7
ENST00000356990.5
ENST00000235150.4
RNF19B
ring finger protein 19B
chr6_+_161123270 0.17 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
PLG
plasminogen
chr1_+_161494036 0.17 ENST00000309758.4
HSPA6
heat shock 70kDa protein 6 (HSP70B')
chr2_-_225811747 0.17 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr18_+_616672 0.17 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr5_+_140593509 0.16 ENST00000341948.4
PCDHB13
protocadherin beta 13
chr3_-_114790179 0.16 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr6_+_160542821 0.16 ENST00000366963.4
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr4_-_70518941 0.16 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1
UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr7_-_25702669 0.16 ENST00000446840.1
AC003090.1
AC003090.1
chr22_+_21996549 0.16 ENST00000248958.4
SDF2L1
stromal cell-derived factor 2-like 1
chrX_-_100872911 0.16 ENST00000361910.4
ENST00000539247.1
ENST00000538627.1
ARMCX6
armadillo repeat containing, X-linked 6
chr12_+_75874580 0.16 ENST00000456650.3
GLIPR1
GLI pathogenesis-related 1
chr8_-_93978216 0.16 ENST00000517751.1
ENST00000524107.1
TRIQK
triple QxxK/R motif containing
chr12_-_70093235 0.15 ENST00000266661.4
BEST3
bestrophin 3
chr17_-_43045439 0.15 ENST00000253407.3
C1QL1
complement component 1, q subcomponent-like 1
chr13_-_30160925 0.15 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr5_+_81575281 0.15 ENST00000380167.4
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chrX_-_15332665 0.15 ENST00000537676.1
ENST00000344384.4
ASB11
ankyrin repeat and SOCS box containing 11
chr12_+_14369524 0.15 ENST00000538329.1
RP11-134N1.2
RP11-134N1.2
chr13_+_24144796 0.15 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr14_+_32798547 0.15 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr11_+_122733011 0.15 ENST00000533709.1
CRTAM
cytotoxic and regulatory T cell molecule
chr1_+_159272111 0.15 ENST00000368114.1
FCER1A
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
chr14_+_39944025 0.15 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
RP11-111A21.1
chr1_+_12976450 0.15 ENST00000361079.2
PRAMEF7
PRAME family member 7
chr12_-_31478428 0.15 ENST00000543615.1
FAM60A
family with sequence similarity 60, member A
chr19_+_45417921 0.15 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
APOC1
apolipoprotein C-I
chr15_+_66679155 0.15 ENST00000307102.5
MAP2K1
mitogen-activated protein kinase kinase 1
chr6_-_32557610 0.15 ENST00000360004.5
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
chr19_+_4247070 0.14 ENST00000262962.7
CCDC94
coiled-coil domain containing 94
chr11_+_74811578 0.14 ENST00000531713.1
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chrX_+_10126488 0.14 ENST00000380829.1
ENST00000421085.2
ENST00000454850.1
CLCN4
chloride channel, voltage-sensitive 4
chr2_-_114461655 0.14 ENST00000424612.1
AC017074.2
AC017074.2
chr13_+_111837279 0.14 ENST00000467053.1
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr14_+_56584414 0.14 ENST00000559044.1
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr2_+_220143989 0.14 ENST00000336576.5
DNAJB2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr4_+_158493642 0.14 ENST00000507108.1
ENST00000455598.1
ENST00000509450.1
RP11-364P22.1
RP11-364P22.1
chr14_+_103851712 0.14 ENST00000440884.3
ENST00000416682.2
ENST00000429436.2
ENST00000303622.9
MARK3
MAP/microtubule affinity-regulating kinase 3
chr7_-_87856303 0.14 ENST00000394641.3
SRI
sorcin
chr14_+_24641062 0.14 ENST00000311457.3
ENST00000557806.1
ENST00000559919.1
REC8
REC8 meiotic recombination protein
chr16_+_22524844 0.14 ENST00000538606.1
ENST00000424340.1
ENST00000517539.1
ENST00000528249.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr5_+_175490540 0.14 ENST00000515817.1
FAM153B
family with sequence similarity 153, member B
chr3_-_186524144 0.14 ENST00000427785.1
RFC4
replication factor C (activator 1) 4, 37kDa
chr1_-_67600639 0.14 ENST00000544837.1
ENST00000603691.1
C1orf141
chromosome 1 open reading frame 141
chr17_+_61473104 0.14 ENST00000583016.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr12_-_22063787 0.14 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr3_+_52245458 0.14 ENST00000459884.1
ALAS1
aminolevulinate, delta-, synthase 1
chr5_-_139726181 0.14 ENST00000507104.1
ENST00000230990.6
HBEGF
heparin-binding EGF-like growth factor
chr15_+_25068773 0.14 ENST00000400100.1
ENST00000400098.1
SNRPN
small nuclear ribonucleoprotein polypeptide N
chrX_-_13835147 0.14 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr11_-_128894053 0.14 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr1_-_92952433 0.14 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chrX_-_55208866 0.14 ENST00000545075.1
MTRNR2L10
MT-RNR2-like 10
chr5_+_140480083 0.14 ENST00000231130.2
PCDHB3
protocadherin beta 3
chrX_+_100224676 0.13 ENST00000450049.2
ARL13A
ADP-ribosylation factor-like 13A
chr12_-_91546926 0.13 ENST00000550758.1
DCN
decorin
chr19_+_2785458 0.13 ENST00000307741.6
ENST00000585338.1
THOP1
thimet oligopeptidase 1
chr3_-_52719546 0.13 ENST00000439181.1
ENST00000449505.1
PBRM1
polybromo 1
chr11_-_58612168 0.13 ENST00000287275.1
GLYATL2
glycine-N-acyltransferase-like 2
chr5_-_81574160 0.13 ENST00000510210.1
ENST00000512493.1
ENST00000507980.1
ENST00000511844.1
ENST00000510019.1
RPS23
ribosomal protein S23
chr2_+_101591314 0.13 ENST00000450763.1
NPAS2
neuronal PAS domain protein 2
chr22_-_50970919 0.13 ENST00000329363.4
ENST00000437588.1
ODF3B
outer dense fiber of sperm tails 3B
chr22_+_17956618 0.13 ENST00000262608.8
CECR2
cat eye syndrome chromosome region, candidate 2
chr11_-_85376121 0.13 ENST00000527447.1
CREBZF
CREB/ATF bZIP transcription factor
chrX_-_21776281 0.13 ENST00000379494.3
SMPX
small muscle protein, X-linked
chr8_-_41166953 0.13 ENST00000220772.3
SFRP1
secreted frizzled-related protein 1
chr19_-_54618650 0.13 ENST00000391757.1
TFPT
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr5_+_140227357 0.13 ENST00000378122.3
PCDHA9
protocadherin alpha 9
chr1_-_13390765 0.13 ENST00000357367.2
PRAMEF8
PRAME family member 8
chr11_-_4414880 0.13 ENST00000254436.7
ENST00000543625.1
TRIM21
tripartite motif containing 21
chr2_-_136633940 0.13 ENST00000264156.2
MCM6
minichromosome maintenance complex component 6
chr18_+_22040620 0.13 ENST00000426880.2
HRH4
histamine receptor H4
chr17_-_57158523 0.13 ENST00000581468.1
TRIM37
tripartite motif containing 37
chr17_+_41561317 0.13 ENST00000540306.1
ENST00000262415.3
ENST00000605777.1
DHX8
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr7_-_100493482 0.12 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
ACHE
acetylcholinesterase (Yt blood group)
chr17_+_66511540 0.12 ENST00000588188.2
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr5_+_140514782 0.12 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr17_+_79650962 0.12 ENST00000329138.4
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr5_-_94417314 0.12 ENST00000505208.1
MCTP1
multiple C2 domains, transmembrane 1
chr9_+_19049372 0.12 ENST00000380527.1
RRAGA
Ras-related GTP binding A
chr19_-_58951496 0.12 ENST00000254166.3
ZNF132
zinc finger protein 132
chr2_+_182850743 0.12 ENST00000409702.1
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr1_+_158979680 0.12 ENST00000368131.4
ENST00000340979.6
IFI16
interferon, gamma-inducible protein 16
chr17_-_19015945 0.12 ENST00000573866.2
SNORD3D
small nucleolar RNA, C/D box 3D
chr7_+_137761167 0.12 ENST00000432161.1
AKR1D1
aldo-keto reductase family 1, member D1
chr6_+_3259148 0.12 ENST00000419065.2
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr17_+_19091325 0.12 ENST00000584923.1
SNORD3A
small nucleolar RNA, C/D box 3A
chr1_+_158979686 0.12 ENST00000368132.3
ENST00000295809.7
IFI16
interferon, gamma-inducible protein 16
chr12_+_75874460 0.12 ENST00000266659.3
GLIPR1
GLI pathogenesis-related 1
chr16_-_66583994 0.12 ENST00000564917.1
TK2
thymidine kinase 2, mitochondrial
chr3_-_101039402 0.12 ENST00000193391.7
IMPG2
interphotoreceptor matrix proteoglycan 2
chrX_+_19362011 0.12 ENST00000379806.5
ENST00000545074.1
ENST00000540249.1
ENST00000423505.1
ENST00000417819.1
ENST00000422285.2
ENST00000355808.5
ENST00000379805.3
PDHA1
pyruvate dehydrogenase (lipoamide) alpha 1
chr1_+_158979792 0.12 ENST00000359709.3
ENST00000430894.2
IFI16
interferon, gamma-inducible protein 16
chr11_-_65149422 0.12 ENST00000526432.1
ENST00000527174.1
SLC25A45
solute carrier family 25, member 45
chr19_-_54619006 0.12 ENST00000391759.1
TFPT
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr7_+_96634850 0.12 ENST00000518156.2
DLX6
distal-less homeobox 6
chr12_+_75874984 0.12 ENST00000550491.1
GLIPR1
GLI pathogenesis-related 1
chr5_-_94417186 0.12 ENST00000312216.8
ENST00000512425.1
MCTP1
multiple C2 domains, transmembrane 1
chr7_+_100551239 0.11 ENST00000319509.7
MUC3A
mucin 3A, cell surface associated

Network of associatons between targets according to the STRING database.

First level regulatory network of SHOX2_HOXC5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.3 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.1 0.3 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 0.3 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.1 0.6 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.3 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 0.2 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.1 0.2 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.3 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.2 GO:0036269 swimming behavior(GO:0036269)
0.1 0.2 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 0.2 GO:0061743 motor learning(GO:0061743) maintenance of synapse structure(GO:0099558)
0.0 0.1 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.2 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.2 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0 0.2 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.0 GO:0003292 cardiac septum cell differentiation(GO:0003292) atrioventricular node cell differentiation(GO:0060922) atrioventricular node cell development(GO:0060928)
0.0 0.2 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.0 0.1 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.0 0.1 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:0061580 colon epithelial cell migration(GO:0061580)
0.0 0.1 GO:0050912 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.0 0.1 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731)
0.0 0.1 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.2 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.1 GO:0001897 cytolysis by symbiont of host cells(GO:0001897)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.0 GO:0042542 response to hydrogen peroxide(GO:0042542)
0.0 0.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) negative regulation of heart rate(GO:0010459) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.1 GO:0017143 insecticide metabolic process(GO:0017143) cellular response to luteinizing hormone stimulus(GO:0071373)
0.0 0.2 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.3 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.1 GO:0015822 mitochondrial ornithine transport(GO:0000066) ornithine transport(GO:0015822)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.1 GO:0009183 purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
0.0 0.7 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.1 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.2 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.3 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.1 GO:0003095 pressure natriuresis(GO:0003095)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.0 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.0 0.1 GO:0002669 tolerance induction dependent upon immune response(GO:0002461) positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.4 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.4 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.2 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0015920 leukocyte chemotaxis involved in inflammatory response(GO:0002232) lipopolysaccharide transport(GO:0015920)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.1 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.0 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.0 0.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.1 GO:0046098 guanine metabolic process(GO:0046098)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.1 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.0 GO:0043474 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.1 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0050705 regulation of interleukin-1 alpha secretion(GO:0050705)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.0 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.0 GO:2000224 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.0 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.1 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.0 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.0 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.0 0.2 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.0 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.3 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.0 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.1 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070) positive regulation of glucose mediated signaling pathway(GO:1902661)
0.0 0.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.2 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.0 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.0 0.4 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.8 GO:0070206 protein trimerization(GO:0070206)
0.0 0.1 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.0 GO:1904875 regulation of DNA ligase activity(GO:1904875)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.2 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.2 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.2 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.2 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.1 GO:0044301 climbing fiber(GO:0044301)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.5 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.2 GO:0032010 phagolysosome(GO:0032010)
0.0 0.2 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.3 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.0 GO:0036502 Derlin-1-VIMP complex(GO:0036502)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 0.4 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 0.3 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.4 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.1 0.2 GO:0070996 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783) type 1 melanocortin receptor binding(GO:0070996)
0.1 0.2 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375)
0.1 1.2 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.2 GO:1904854 proteasome core complex binding(GO:1904854)
0.1 0.3 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.5 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.2 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.2 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.1 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0008124 phenylalanine 4-monooxygenase activity(GO:0004505) 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.0 0.1 GO:1902271 D3 vitamins binding(GO:1902271)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.3 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.2 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.0 0.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.4 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.0 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0004040 amidase activity(GO:0004040)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.0 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.1 GO:0004132 dCMP deaminase activity(GO:0004132)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.1 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.0 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.0 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.0 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350) glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
0.0 0.1 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.0 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.0 GO:0035240 dopamine binding(GO:0035240)
0.0 0.1 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.0 GO:0070035 ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.0 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex