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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for SOX10_SOX15

Z-value: 1.02

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Transcription factors associated with SOX10_SOX15

Gene Symbol Gene ID Gene Info
SOX10
ENSG00000100146.12 SRY-box transcription factor 10
SOX15
ENSG00000129194.3 SRY-box transcription factor 15

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX15hg19_v2_chr17_-_7493390_7493488-0.168.4e-01Click!

Activity profile of SOX10_SOX15 motif

Sorted Z-values of SOX10_SOX15 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_76649546 1.09 ENST00000508510.1
ENST00000509561.1
ENST00000499709.2
ENST00000511868.1
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr12_+_95611536 0.99 ENST00000549002.1
VEZT
vezatin, adherens junctions transmembrane protein
chr6_+_64282447 0.92 ENST00000370650.2
ENST00000578299.1
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr5_+_31193847 0.86 ENST00000514738.1
ENST00000265071.2
CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr3_-_148939598 0.80 ENST00000455472.3
CP
ceruloplasmin (ferroxidase)
chr12_-_42631529 0.71 ENST00000548917.1
YAF2
YY1 associated factor 2
chr2_-_37501692 0.68 ENST00000443977.1
PRKD3
protein kinase D3
chr1_-_26233423 0.64 ENST00000357865.2
STMN1
stathmin 1
chr22_-_39052300 0.64 ENST00000355830.6
FAM227A
family with sequence similarity 227, member A
chr10_-_75351088 0.63 ENST00000451492.1
ENST00000413442.1
USP54
ubiquitin specific peptidase 54
chr15_+_57210961 0.57 ENST00000557843.1
TCF12
transcription factor 12
chr9_-_123476612 0.54 ENST00000426959.1
MEGF9
multiple EGF-like-domains 9
chr14_-_50583271 0.53 ENST00000395860.2
ENST00000395859.2
VCPKMT
valosin containing protein lysine (K) methyltransferase
chrX_+_80457442 0.53 ENST00000373212.5
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr5_+_149865377 0.53 ENST00000522491.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr3_-_167813672 0.51 ENST00000470487.1
GOLIM4
golgi integral membrane protein 4
chr4_+_95128748 0.51 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr4_+_95128996 0.51 ENST00000457823.2
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr1_+_228337553 0.50 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa
chr14_-_65409438 0.49 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr4_+_95129061 0.48 ENST00000354268.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr4_-_140477910 0.47 ENST00000404104.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr12_+_8849773 0.47 ENST00000541044.1
RIMKLB
ribosomal modification protein rimK-like family member B
chr14_-_31495569 0.46 ENST00000357479.5
ENST00000355683.5
STRN3
striatin, calmodulin binding protein 3
chr6_+_83777374 0.43 ENST00000349129.2
ENST00000237163.5
ENST00000536812.1
DOPEY1
dopey family member 1
chr20_+_60718785 0.41 ENST00000421564.1
ENST00000450482.1
ENST00000331758.3
SS18L1
synovial sarcoma translocation gene on chromosome 18-like 1
chr11_-_8892464 0.41 ENST00000527347.1
ENST00000526241.1
ENST00000526126.1
ENST00000530938.1
ENST00000526057.1
ST5
suppression of tumorigenicity 5
chr14_-_80678512 0.40 ENST00000553968.1
DIO2
deiodinase, iodothyronine, type II
chr4_-_140477928 0.38 ENST00000274031.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr6_-_64029879 0.38 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN
lengsin, lens protein with glutamine synthetase domain
chr2_+_70056762 0.38 ENST00000282570.3
GMCL1
germ cell-less, spermatogenesis associated 1
chr15_+_52043813 0.36 ENST00000435126.2
TMOD2
tropomodulin 2 (neuronal)
chr14_-_65409502 0.36 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr6_-_134861089 0.35 ENST00000606039.1
RP11-557H15.4
RP11-557H15.4
chr15_+_57210818 0.34 ENST00000438423.2
ENST00000267811.5
ENST00000452095.2
ENST00000559609.1
ENST00000333725.5
TCF12
transcription factor 12
chrX_-_45629661 0.33 ENST00000602507.1
ENST00000602461.1
RP6-99M1.2
RP6-99M1.2
chr3_+_151986709 0.33 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
MBNL1
muscleblind-like splicing regulator 1
chrX_-_63425561 0.32 ENST00000374869.3
ENST00000330258.3
AMER1
APC membrane recruitment protein 1
chr10_-_99094458 0.32 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr1_-_93645818 0.32 ENST00000370280.1
ENST00000479918.1
TMED5
transmembrane emp24 protein transport domain containing 5
chr3_-_123339343 0.32 ENST00000578202.1
MYLK
myosin light chain kinase
chr3_+_189349162 0.31 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63
tumor protein p63
chr1_-_65533390 0.31 ENST00000448344.1
RP4-535B20.1
RP4-535B20.1
chrX_-_131352152 0.30 ENST00000342983.2
RAP2C
RAP2C, member of RAS oncogene family
chr14_+_38065052 0.30 ENST00000556845.1
TTC6
tetratricopeptide repeat domain 6
chr5_-_138718973 0.30 ENST00000353963.3
ENST00000348729.3
SLC23A1
solute carrier family 23 (ascorbic acid transporter), member 1
chr11_-_76155618 0.30 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr12_+_50479101 0.30 ENST00000551966.1
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr1_+_93913713 0.29 ENST00000604705.1
ENST00000370253.2
FNBP1L
formin binding protein 1-like
chr15_+_52311398 0.29 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr2_-_204400013 0.28 ENST00000374489.2
ENST00000374488.2
ENST00000308091.4
ENST00000453034.1
ENST00000420371.1
RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr15_+_52043758 0.28 ENST00000249700.4
ENST00000539962.2
TMOD2
tropomodulin 2 (neuronal)
chr3_-_27525826 0.28 ENST00000454389.1
ENST00000440156.1
ENST00000437179.1
ENST00000446700.1
ENST00000455077.1
ENST00000435667.2
ENST00000388777.4
ENST00000425128.2
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr7_+_23146271 0.28 ENST00000545771.1
KLHL7
kelch-like family member 7
chr6_+_122720681 0.28 ENST00000368455.4
ENST00000452194.1
HSF2
heat shock transcription factor 2
chr4_+_76649797 0.27 ENST00000538159.1
ENST00000514213.2
USO1
USO1 vesicle transport factor
chr3_+_181429704 0.27 ENST00000431565.2
ENST00000325404.1
SOX2
SRY (sex determining region Y)-box 2
chr4_+_154387480 0.27 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
KIAA0922
KIAA0922
chr6_+_43968306 0.27 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223
chromosome 6 open reading frame 223
chr13_-_41593425 0.26 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr9_-_123476719 0.26 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr16_+_30934376 0.26 ENST00000562798.1
ENST00000471231.2
FBXL19
F-box and leucine-rich repeat protein 19
chr17_-_49124230 0.26 ENST00000510283.1
ENST00000510855.1
SPAG9
sperm associated antigen 9
chr2_+_27070964 0.26 ENST00000288699.6
DPYSL5
dihydropyrimidinase-like 5
chr15_+_101402041 0.26 ENST00000558475.1
ENST00000558641.1
ENST00000559673.1
RP11-66B24.1
RP11-66B24.1
chr6_-_111888474 0.25 ENST00000368735.1
TRAF3IP2
TRAF3 interacting protein 2
chr18_-_74728998 0.24 ENST00000359645.3
ENST00000397875.3
ENST00000397869.3
ENST00000578193.1
ENST00000578873.1
ENST00000397866.4
ENST00000528160.1
ENST00000527041.1
ENST00000526111.1
ENST00000397865.5
ENST00000382582.3
MBP
myelin basic protein
chr16_+_53242350 0.24 ENST00000565442.1
CHD9
chromodomain helicase DNA binding protein 9
chr17_+_27920486 0.24 ENST00000394859.3
ANKRD13B
ankyrin repeat domain 13B
chr4_+_90033968 0.24 ENST00000317005.2
TIGD2
tigger transposable element derived 2
chr2_-_118943930 0.23 ENST00000449075.1
ENST00000414886.1
ENST00000449819.1
AC093901.1
AC093901.1
chr4_+_76649753 0.23 ENST00000603759.1
USO1
USO1 vesicle transport factor
chr5_+_149865838 0.23 ENST00000519157.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr10_+_114710211 0.23 ENST00000349937.2
ENST00000369397.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr8_+_21777159 0.23 ENST00000434536.1
ENST00000252512.9
XPO7
exportin 7
chr11_-_66445219 0.23 ENST00000525754.1
ENST00000531969.1
ENST00000524637.1
ENST00000531036.2
ENST00000310046.4
RBM4B
RNA binding motif protein 4B
chr4_-_164534657 0.23 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr14_-_71107921 0.23 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
CTD-2540L5.5
CTD-2540L5.6
chr5_+_137514834 0.22 ENST00000508792.1
ENST00000504621.1
KIF20A
kinesin family member 20A
chr2_-_85625857 0.22 ENST00000453973.1
CAPG
capping protein (actin filament), gelsolin-like
chr12_-_58145889 0.22 ENST00000547853.1
CDK4
cyclin-dependent kinase 4
chr6_+_119215308 0.22 ENST00000229595.5
ASF1A
anti-silencing function 1A histone chaperone
chr15_-_80695917 0.22 ENST00000559008.1
RP11-210M15.2
Uncharacterized protein
chr2_+_32288657 0.22 ENST00000345662.1
SPAST
spastin
chr4_+_113152978 0.22 ENST00000309703.6
AP1AR
adaptor-related protein complex 1 associated regulatory protein
chr2_-_70475701 0.22 ENST00000282574.4
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr12_+_11081828 0.22 ENST00000381847.3
ENST00000396400.3
PRH2
proline-rich protein HaeIII subfamily 2
chr16_-_15736881 0.22 ENST00000540441.2
KIAA0430
KIAA0430
chr2_+_69240302 0.22 ENST00000303714.4
ANTXR1
anthrax toxin receptor 1
chr15_-_52944231 0.22 ENST00000546305.2
FAM214A
family with sequence similarity 214, member A
chr14_-_67981916 0.21 ENST00000357461.2
TMEM229B
transmembrane protein 229B
chr3_-_57583052 0.21 ENST00000496292.1
ENST00000489843.1
ARF4
ADP-ribosylation factor 4
chr3_-_148939835 0.21 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr10_+_114709999 0.21 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr7_+_102553430 0.21 ENST00000339431.4
ENST00000249377.4
LRRC17
leucine rich repeat containing 17
chr2_+_181845843 0.21 ENST00000602710.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr10_-_14613968 0.21 ENST00000488576.1
ENST00000472095.1
FAM107B
family with sequence similarity 107, member B
chr11_-_111781610 0.21 ENST00000525823.1
CRYAB
crystallin, alpha B
chr1_-_114355083 0.20 ENST00000261441.5
RSBN1
round spermatid basic protein 1
chrX_-_106960285 0.20 ENST00000503515.1
ENST00000372397.2
TSC22D3
TSC22 domain family, member 3
chr4_+_106067943 0.20 ENST00000380013.4
ENST00000394764.1
ENST00000413648.2
TET2
tet methylcytosine dioxygenase 2
chr16_+_53483983 0.20 ENST00000544545.1
RBL2
retinoblastoma-like 2 (p130)
chr16_-_30798492 0.20 ENST00000262525.4
ZNF629
zinc finger protein 629
chr8_-_80993010 0.20 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
TPD52
tumor protein D52
chr1_+_183774240 0.20 ENST00000360851.3
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr1_+_93645314 0.20 ENST00000343253.7
CCDC18
coiled-coil domain containing 18
chr10_-_735553 0.20 ENST00000280886.6
ENST00000423550.1
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr10_-_70092671 0.20 ENST00000358769.2
ENST00000432941.1
ENST00000495025.2
PBLD
phenazine biosynthesis-like protein domain containing
chr3_-_48470838 0.20 ENST00000358459.4
ENST00000358536.4
PLXNB1
plexin B1
chr5_-_111092930 0.20 ENST00000257435.7
NREP
neuronal regeneration related protein
chr5_-_14871866 0.20 ENST00000284268.6
ANKH
ANKH inorganic pyrophosphate transport regulator
chr6_+_30689350 0.20 ENST00000330914.3
TUBB
tubulin, beta class I
chr20_+_48884002 0.19 ENST00000425497.1
ENST00000445003.1
RP11-290F20.3
RP11-290F20.3
chr2_-_70475730 0.19 ENST00000445587.1
ENST00000433529.2
ENST00000415783.2
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr7_+_74379083 0.19 ENST00000361825.7
GATSL1
GATS protein-like 1
chr19_+_13228917 0.19 ENST00000586171.1
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr10_-_70092635 0.19 ENST00000309049.4
PBLD
phenazine biosynthesis-like protein domain containing
chr17_-_46623441 0.19 ENST00000330070.4
HOXB2
homeobox B2
chr19_+_1249869 0.19 ENST00000591446.2
MIDN
midnolin
chr12_-_71551868 0.19 ENST00000247829.3
TSPAN8
tetraspanin 8
chr5_+_137514687 0.19 ENST00000394894.3
KIF20A
kinesin family member 20A
chr2_+_120517174 0.18 ENST00000263708.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr12_-_2966193 0.18 ENST00000382678.3
AC005841.1
Uncharacterized protein ENSP00000372125
chr11_-_111781454 0.18 ENST00000533280.1
CRYAB
crystallin, alpha B
chr22_+_31742875 0.18 ENST00000504184.2
AC005003.1
CDNA FLJ20464 fis, clone KAT06158; HCG1777549; Uncharacterized protein
chrX_-_135962876 0.18 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RBMX
RNA binding motif protein, X-linked
chr5_-_135701164 0.18 ENST00000355180.3
ENST00000426057.2
ENST00000513104.1
TRPC7
transient receptor potential cation channel, subfamily C, member 7
chr1_+_68150744 0.18 ENST00000370986.4
ENST00000370985.3
GADD45A
growth arrest and DNA-damage-inducible, alpha
chr12_-_105478339 0.17 ENST00000424857.2
ENST00000258494.9
ALDH1L2
aldehyde dehydrogenase 1 family, member L2
chr7_+_116660246 0.17 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
ST7
suppression of tumorigenicity 7
chr12_+_53443963 0.17 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr2_-_47572105 0.17 ENST00000419035.1
ENST00000448713.1
ENST00000450550.1
ENST00000413185.2
AC073283.4
AC073283.4
chr5_-_111092873 0.17 ENST00000509025.1
ENST00000515855.1
NREP
neuronal regeneration related protein
chr6_+_151358048 0.17 ENST00000450635.1
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr12_+_53443680 0.17 ENST00000314250.6
ENST00000451358.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr3_-_149688971 0.17 ENST00000498307.1
ENST00000489155.1
PFN2
profilin 2
chr4_+_113152881 0.17 ENST00000274000.5
AP1AR
adaptor-related protein complex 1 associated regulatory protein
chr14_-_67981870 0.16 ENST00000555994.1
TMEM229B
transmembrane protein 229B
chr6_+_108881012 0.16 ENST00000343882.6
FOXO3
forkhead box O3
chr9_+_103235365 0.16 ENST00000374879.4
TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr7_+_30185406 0.16 ENST00000324489.5
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr2_+_32288725 0.16 ENST00000315285.3
SPAST
spastin
chr14_-_91884115 0.16 ENST00000389857.6
CCDC88C
coiled-coil domain containing 88C
chr8_-_17579726 0.16 ENST00000381861.3
MTUS1
microtubule associated tumor suppressor 1
chr12_-_102591604 0.16 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr7_+_29234101 0.16 ENST00000435288.2
CHN2
chimerin 2
chr14_-_51027838 0.16 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr5_+_78532003 0.15 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr1_-_204436344 0.15 ENST00000367184.2
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr21_-_40720995 0.15 ENST00000380749.5
HMGN1
high mobility group nucleosome binding domain 1
chr22_-_23484246 0.15 ENST00000216036.4
RTDR1
rhabdoid tumor deletion region gene 1
chr7_-_32111009 0.15 ENST00000396184.3
ENST00000396189.2
ENST00000321453.7
PDE1C
phosphodiesterase 1C, calmodulin-dependent 70kDa
chr1_-_6479963 0.15 ENST00000377836.4
ENST00000487437.1
ENST00000489730.1
ENST00000377834.4
HES2
hes family bHLH transcription factor 2
chr1_-_151431909 0.14 ENST00000361398.3
ENST00000271715.2
POGZ
pogo transposable element with ZNF domain
chrX_+_37639302 0.14 ENST00000545017.1
ENST00000536160.1
CYBB
cytochrome b-245, beta polypeptide
chr6_+_87865262 0.14 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292
zinc finger protein 292
chr18_+_20494078 0.14 ENST00000579124.1
ENST00000577588.1
ENST00000582354.1
ENST00000581819.1
RBBP8
retinoblastoma binding protein 8
chrX_+_129473859 0.14 ENST00000424447.1
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr2_-_37899323 0.14 ENST00000295324.3
ENST00000457889.1
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr11_-_102323489 0.14 ENST00000361236.3
TMEM123
transmembrane protein 123
chr5_+_137514403 0.14 ENST00000513276.1
KIF20A
kinesin family member 20A
chr5_+_65222438 0.14 ENST00000380938.2
ERBB2IP
erbb2 interacting protein
chr6_-_29527702 0.13 ENST00000377050.4
UBD
ubiquitin D
chr21_-_16437126 0.13 ENST00000318948.4
NRIP1
nuclear receptor interacting protein 1
chr11_-_102323740 0.13 ENST00000398136.2
TMEM123
transmembrane protein 123
chr21_-_16437255 0.13 ENST00000400199.1
ENST00000400202.1
NRIP1
nuclear receptor interacting protein 1
chr9_+_128510454 0.13 ENST00000491787.3
ENST00000447726.2
PBX3
pre-B-cell leukemia homeobox 3
chr9_-_119162885 0.13 ENST00000445861.2
PAPPA-AS1
PAPPA antisense RNA 1
chr15_+_58724184 0.13 ENST00000433326.2
LIPC
lipase, hepatic
chr1_+_166808667 0.13 ENST00000537173.1
ENST00000536514.1
ENST00000449930.1
POGK
pogo transposable element with KRAB domain
chr17_+_53046096 0.13 ENST00000376352.2
ENST00000299341.4
ENST00000405898.1
ENST00000434978.2
ENST00000398391.2
STXBP4
syntaxin binding protein 4
chr7_-_94953878 0.13 ENST00000222381.3
PON1
paraoxonase 1
chr21_-_40720974 0.13 ENST00000380748.1
HMGN1
high mobility group nucleosome binding domain 1
chr6_+_74405804 0.13 ENST00000287097.5
CD109
CD109 molecule
chr7_+_73868439 0.13 ENST00000424337.2
GTF2IRD1
GTF2I repeat domain containing 1
chr6_+_74405501 0.13 ENST00000437994.2
ENST00000422508.2
CD109
CD109 molecule
chr12_+_104359576 0.13 ENST00000392872.3
ENST00000436021.2
TDG
thymine-DNA glycosylase
chr10_+_97803151 0.13 ENST00000403870.3
ENST00000265992.5
ENST00000465148.2
ENST00000534974.1
CCNJ
cyclin J
chr3_-_167813132 0.13 ENST00000309027.4
GOLIM4
golgi integral membrane protein 4
chr3_-_52719888 0.13 ENST00000458294.1
PBRM1
polybromo 1
chr5_-_141338377 0.13 ENST00000510041.1
PCDH12
protocadherin 12
chr20_-_52645231 0.13 ENST00000448484.1
BCAS1
breast carcinoma amplified sequence 1
chr5_-_138780159 0.13 ENST00000512473.1
ENST00000515581.1
ENST00000515277.1
DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chrX_+_70443050 0.13 ENST00000361726.6
GJB1
gap junction protein, beta 1, 32kDa
chr4_-_5890145 0.13 ENST00000397890.2
CRMP1
collapsin response mediator protein 1
chr21_+_30671690 0.12 ENST00000399921.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr12_-_12419703 0.12 ENST00000543091.1
ENST00000261349.4
LRP6
low density lipoprotein receptor-related protein 6
chr14_-_50999190 0.12 ENST00000557390.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr14_+_97263641 0.12 ENST00000216639.3
VRK1
vaccinia related kinase 1
chr4_-_40516560 0.12 ENST00000513473.1
RBM47
RNA binding motif protein 47
chr11_-_111781554 0.12 ENST00000526167.1
ENST00000528961.1
CRYAB
crystallin, alpha B
chrX_+_84498989 0.12 ENST00000395402.1
ZNF711
zinc finger protein 711
chr21_+_35553045 0.12 ENST00000416145.1
ENST00000430922.1
ENST00000419881.2
LINC00310
long intergenic non-protein coding RNA 310
chr10_-_14614311 0.12 ENST00000479731.1
ENST00000468492.1
FAM107B
family with sequence similarity 107, member B
chr15_+_62359175 0.12 ENST00000355522.5
C2CD4A
C2 calcium-dependent domain containing 4A
chr7_-_15601595 0.12 ENST00000342526.3
AGMO
alkylglycerol monooxygenase
chr11_-_64013663 0.12 ENST00000392210.2
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr2_-_86564740 0.12 ENST00000540790.1
ENST00000428491.1
REEP1
receptor accessory protein 1
chr11_-_117166276 0.12 ENST00000510630.1
ENST00000392937.6
BACE1
beta-site APP-cleaving enzyme 1
chr14_-_95236551 0.12 ENST00000238558.3
GSC
goosecoid homeobox

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX10_SOX15

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0060996 dendritic spine development(GO:0060996) regulation of dendritic spine development(GO:0060998) positive regulation of dendritic spine development(GO:0060999)
0.1 0.6 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.4 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1 0.4 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.3 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.4 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.3 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.6 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.7 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.2 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.1 0.6 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.7 GO:0006477 protein sulfation(GO:0006477)
0.1 0.9 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 1.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.4 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.2 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.3 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.2 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 1.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.2 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.1 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.1 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.1 GO:0035261 external genitalia morphogenesis(GO:0035261)
0.0 0.4 GO:0051013 microtubule severing(GO:0051013)
0.0 0.4 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.3 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.3 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.2 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.0 0.2 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.6 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 1.0 GO:0006825 copper ion transport(GO:0006825)
0.0 0.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.1 GO:1904586 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.0 0.5 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:0008057 eye pigment granule organization(GO:0008057)
0.0 0.3 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.1 GO:1903452 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.1 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.0 0.4 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0003192 mitral valve formation(GO:0003192)
0.0 0.1 GO:1902811 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.5 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.0 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.4 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.1 GO:0046661 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546) male sex differentiation(GO:0046661)
0.0 0.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.1 GO:0090166 histone-threonine phosphorylation(GO:0035405) Golgi disassembly(GO:0090166)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.0 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.0 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.2 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.0 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0072501 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.3 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.3 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.1 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.4 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.5 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 1.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.7 GO:0071565 nBAF complex(GO:0071565)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 1.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290) Flemming body(GO:0090543)
0.0 0.1 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.1 0.8 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.3 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.1 0.4 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.3 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.4 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 1.0 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.5 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 0.4 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.1 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.0 0.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.7 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.8 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.6 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 1.4 GO:0016279 protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.1 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.0 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade