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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for SOX7

Z-value: 1.01

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Transcription factors associated with SOX7

Gene Symbol Gene ID Gene Info
SOX7
ENSG00000171056.6 SRY-box transcription factor 7
SOX7
ENSG00000258724.1 SRY-box transcription factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX7hg19_v2_chr8_-_10588010_10588030-0.722.8e-01Click!

Activity profile of SOX7 motif

Sorted Z-values of SOX7 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_190445499 1.31 ENST00000261024.2
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr12_-_57443886 1.07 ENST00000300119.3
MYO1A
myosin IA
chr2_-_152118276 0.88 ENST00000409092.1
RBM43
RNA binding motif protein 43
chr21_+_34144411 0.86 ENST00000382375.4
ENST00000453404.1
ENST00000382378.1
ENST00000477513.1
C21orf49
chromosome 21 open reading frame 49
chr1_+_100598691 0.73 ENST00000370143.1
ENST00000370141.2
TRMT13
tRNA methyltransferase 13 homolog (S. cerevisiae)
chr12_-_90049878 0.72 ENST00000359142.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chrY_+_14813160 0.69 ENST00000338981.3
USP9Y
ubiquitin specific peptidase 9, Y-linked
chr12_-_90049828 0.60 ENST00000261173.2
ENST00000348959.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr4_-_39034542 0.59 ENST00000344606.6
TMEM156
transmembrane protein 156
chr8_-_102803163 0.56 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD
neurocalcin delta
chr12_+_64173583 0.50 ENST00000261234.6
TMEM5
transmembrane protein 5
chr10_-_71169031 0.50 ENST00000373307.1
TACR2
tachykinin receptor 2
chr19_-_21950332 0.48 ENST00000598026.1
ZNF100
zinc finger protein 100
chr12_-_39734783 0.45 ENST00000552961.1
KIF21A
kinesin family member 21A
chr19_-_5784610 0.43 ENST00000390672.2
ENST00000419421.2
PRR22
proline rich 22
chr10_+_122610687 0.41 ENST00000263461.6
WDR11
WD repeat domain 11
chr2_+_179317994 0.41 ENST00000375129.4
DFNB59
deafness, autosomal recessive 59
chr1_+_10509971 0.40 ENST00000320498.4
CORT
cortistatin
chr3_-_123411191 0.38 ENST00000354792.5
ENST00000508240.1
MYLK
myosin light chain kinase
chr6_-_86303833 0.31 ENST00000505648.1
SNX14
sorting nexin 14
chr10_-_12084770 0.28 ENST00000357604.5
UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr19_-_38916839 0.28 ENST00000433821.2
ENST00000426920.2
ENST00000587753.1
ENST00000454404.2
ENST00000293062.9
RASGRP4
RAS guanyl releasing protein 4
chr19_+_37837185 0.27 ENST00000541583.2
HKR1
HKR1, GLI-Kruppel zinc finger family member
chr15_+_63414760 0.27 ENST00000557972.1
LACTB
lactamase, beta
chr10_+_5005445 0.27 ENST00000380872.4
AKR1C1
aldo-keto reductase family 1, member C1
chr6_+_29555683 0.26 ENST00000383640.2
OR2H2
olfactory receptor, family 2, subfamily H, member 2
chr14_+_60712463 0.25 ENST00000325642.3
ENST00000529574.1
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr3_+_107318157 0.25 ENST00000406780.1
BBX
bobby sox homolog (Drosophila)
chr11_-_62474803 0.24 ENST00000533982.1
ENST00000360796.5
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr10_-_5652705 0.23 ENST00000425246.1
RP11-336A10.5
RP11-336A10.5
chr16_-_28303360 0.21 ENST00000501520.1
RP11-57A19.2
RP11-57A19.2
chr19_+_37837218 0.20 ENST00000591134.1
HKR1
HKR1, GLI-Kruppel zinc finger family member
chr15_+_66585950 0.20 ENST00000525109.1
DIS3L
DIS3 mitotic control homolog (S. cerevisiae)-like
chr17_-_65235916 0.19 ENST00000579861.1
HELZ
helicase with zinc finger
chr6_-_111804905 0.18 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr12_-_57328187 0.18 ENST00000293502.1
SDR9C7
short chain dehydrogenase/reductase family 9C, member 7
chr12_-_58027138 0.18 ENST00000341156.4
B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr14_-_31856397 0.18 ENST00000538864.2
ENST00000550366.1
HEATR5A
HEAT repeat containing 5A
chr18_+_32820990 0.18 ENST00000601719.1
ENST00000591206.1
ENST00000330501.7
ENST00000261333.6
ENST00000355632.4
ENST00000585800.1
ZNF397
zinc finger protein 397
chr1_-_54303934 0.18 ENST00000537333.1
NDC1
NDC1 transmembrane nucleoporin
chr19_-_38916822 0.16 ENST00000586305.1
RASGRP4
RAS guanyl releasing protein 4
chr1_+_100598742 0.14 ENST00000370139.1
TRMT13
tRNA methyltransferase 13 homolog (S. cerevisiae)
chr17_-_28661065 0.14 ENST00000328886.4
ENST00000538566.2
TMIGD1
transmembrane and immunoglobulin domain containing 1
chr5_-_95158644 0.14 ENST00000237858.6
GLRX
glutaredoxin (thioltransferase)
chr17_+_80858418 0.13 ENST00000574422.1
TBCD
tubulin folding cofactor D
chr13_-_28024681 0.13 ENST00000381116.1
ENST00000381120.3
ENST00000431572.2
MTIF3
mitochondrial translational initiation factor 3
chr5_-_95158375 0.13 ENST00000512469.2
ENST00000379979.4
ENST00000505427.1
ENST00000508780.1
GLRX
glutaredoxin (thioltransferase)
chr1_+_40810516 0.12 ENST00000435168.2
SMAP2
small ArfGAP2
chr6_+_168434678 0.10 ENST00000496008.1
KIF25
kinesin family member 25
chr1_-_43751230 0.09 ENST00000523677.1
C1orf210
chromosome 1 open reading frame 210
chr1_+_156698708 0.08 ENST00000519086.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr6_+_147527103 0.07 ENST00000179882.6
STXBP5
syntaxin binding protein 5 (tomosyn)
chr10_-_17243579 0.07 ENST00000525762.1
ENST00000412821.3
ENST00000351358.4
ENST00000377766.5
ENST00000358282.7
ENST00000488990.1
ENST00000377799.3
TRDMT1
tRNA aspartic acid methyltransferase 1
chr17_-_39623681 0.07 ENST00000225899.3
KRT32
keratin 32
chr6_+_150690133 0.06 ENST00000392255.3
ENST00000500320.3
IYD
iodotyrosine deiodinase
chr10_+_96162242 0.06 ENST00000225235.4
TBC1D12
TBC1 domain family, member 12
chr10_-_96829246 0.06 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8
chr6_+_144164455 0.05 ENST00000367576.5
LTV1
LTV1 homolog (S. cerevisiae)
chrX_+_69353284 0.05 ENST00000342206.6
ENST00000356413.4
IGBP1
immunoglobulin (CD79A) binding protein 1
chr12_-_123728548 0.05 ENST00000545406.1
MPHOSPH9
M-phase phosphoprotein 9
chr6_+_80129989 0.04 ENST00000429444.1
RP1-232L24.3
RP1-232L24.3
chr9_-_37592561 0.03 ENST00000544379.1
ENST00000377773.5
ENST00000401811.3
ENST00000321301.6
TOMM5
translocase of outer mitochondrial membrane 5 homolog (yeast)
chr9_-_70465758 0.02 ENST00000489273.1
CBWD5
COBW domain containing 5
chr1_+_158901329 0.01 ENST00000368140.1
ENST00000368138.3
ENST00000392254.2
ENST00000392252.3
ENST00000368135.4
PYHIN1
pyrin and HIN domain family, member 1
chr16_+_28303804 0.00 ENST00000341901.4
SBK1
SH3 domain binding kinase 1
chr6_-_3195981 0.00 ENST00000425384.2
ENST00000435043.2
RP1-40E16.9
RP1-40E16.9

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0070839 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
0.1 1.3 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.1 0.5 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.1 0.2 GO:0070632 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.3 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.2 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 1.1 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.4 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.8 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.2 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.1 1.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.6 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 1.1 GO:0009925 basal plasma membrane(GO:0009925)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 1.3 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 0.3 GO:0047023 androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.0 1.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.8 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.7 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors