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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for SPIB

Z-value: 0.82

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Transcription factors associated with SPIB

Gene Symbol Gene ID Gene Info
SPIB
ENSG00000269404.2 Spi-B transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPIBhg19_v2_chr19_+_50922187_509222150.901.0e-01Click!

Activity profile of SPIB motif

Sorted Z-values of SPIB motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_108921977 0.54 ENST00000430559.1
ENST00000375887.4
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr8_-_131028782 0.53 ENST00000519020.1
FAM49B
family with sequence similarity 49, member B
chr14_-_80678512 0.46 ENST00000553968.1
DIO2
deiodinase, iodothyronine, type II
chr14_+_38065052 0.40 ENST00000556845.1
TTC6
tetratricopeptide repeat domain 6
chr3_-_114035026 0.39 ENST00000570269.1
RP11-553L6.5
RP11-553L6.5
chr22_-_37880543 0.38 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr15_+_91427642 0.37 ENST00000328850.3
ENST00000414248.2
FES
feline sarcoma oncogene
chr15_+_43885799 0.36 ENST00000449946.1
ENST00000417289.1
CKMT1B
creatine kinase, mitochondrial 1B
chr5_-_156390230 0.35 ENST00000407087.3
ENST00000274532.2
TIMD4
T-cell immunoglobulin and mucin domain containing 4
chr17_-_27467418 0.34 ENST00000528564.1
MYO18A
myosin XVIIIA
chr19_+_50919056 0.33 ENST00000599632.1
CTD-2545M3.6
CTD-2545M3.6
chr5_-_64858944 0.32 ENST00000508421.1
ENST00000510693.1
ENST00000514814.1
ENST00000515497.1
ENST00000396679.1
CENPK
centromere protein K
chr8_+_74903580 0.31 ENST00000284818.2
ENST00000518893.1
LY96
lymphocyte antigen 96
chr19_-_42192189 0.29 ENST00000401731.1
ENST00000338196.4
ENST00000006724.3
CEACAM7
carcinoembryonic antigen-related cell adhesion molecule 7
chr16_+_54964740 0.29 ENST00000394636.4
IRX5
iroquois homeobox 5
chr1_-_143913143 0.27 ENST00000400889.1
FAM72D
family with sequence similarity 72, member D
chr3_-_121379739 0.27 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr16_+_12059091 0.26 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr17_+_28443819 0.26 ENST00000479218.2
NSRP1
nuclear speckle splicing regulatory protein 1
chr9_+_104296163 0.25 ENST00000374819.2
ENST00000479306.1
RNF20
ring finger protein 20, E3 ubiquitin protein ligase
chr20_-_62710832 0.25 ENST00000395042.1
RGS19
regulator of G-protein signaling 19
chr19_+_42381337 0.25 ENST00000597454.1
ENST00000444740.2
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr3_+_28390637 0.24 ENST00000420223.1
ENST00000383768.2
ZCWPW2
zinc finger, CW type with PWWP domain 2
chr6_+_49431073 0.24 ENST00000335783.3
CENPQ
centromere protein Q
chr5_-_142783175 0.23 ENST00000231509.3
ENST00000394464.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr15_-_65809991 0.23 ENST00000559526.1
ENST00000358939.4
ENST00000560665.1
ENST00000321118.7
ENST00000339244.5
ENST00000300141.6
DPP8
dipeptidyl-peptidase 8
chr12_+_122018697 0.23 ENST00000541574.1
RP13-941N14.1
RP13-941N14.1
chr20_-_62711259 0.23 ENST00000332298.5
RGS19
regulator of G-protein signaling 19
chr10_+_106028923 0.23 ENST00000338595.2
GSTO2
glutathione S-transferase omega 2
chr2_+_64751433 0.23 ENST00000238856.4
ENST00000422803.1
ENST00000238855.7
AFTPH
aftiphilin
chr3_+_184530173 0.22 ENST00000453056.1
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr6_-_49430886 0.22 ENST00000274813.3
MUT
methylmalonyl CoA mutase
chr5_-_142782862 0.22 ENST00000415690.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr3_+_98482175 0.22 ENST00000485391.1
ENST00000492254.1
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr20_-_46415297 0.22 ENST00000467815.1
ENST00000359930.4
SULF2
sulfatase 2
chr5_+_102455968 0.22 ENST00000358359.3
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr19_-_48867291 0.21 ENST00000435956.3
TMEM143
transmembrane protein 143
chr3_+_16926441 0.21 ENST00000418129.2
ENST00000396755.2
PLCL2
phospholipase C-like 2
chr20_-_46415341 0.21 ENST00000484875.1
ENST00000361612.4
SULF2
sulfatase 2
chr4_-_681114 0.21 ENST00000503156.1
MFSD7
major facilitator superfamily domain containing 7
chr1_+_104068312 0.21 ENST00000524631.1
ENST00000531883.1
ENST00000533099.1
ENST00000527062.1
RNPC3
RNA-binding region (RNP1, RRM) containing 3
chr1_+_164528616 0.21 ENST00000340699.3
PBX1
pre-B-cell leukemia homeobox 1
chr3_-_143567262 0.21 ENST00000474151.1
ENST00000316549.6
SLC9A9
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr20_+_62492566 0.21 ENST00000369916.3
ABHD16B
abhydrolase domain containing 16B
chr6_+_42952237 0.20 ENST00000485511.1
ENST00000394110.3
ENST00000472118.1
ENST00000461010.1
PPP2R5D
protein phosphatase 2, regulatory subunit B', delta
chr1_+_161475208 0.20 ENST00000367972.4
ENST00000271450.6
FCGR2A
Fc fragment of IgG, low affinity IIa, receptor (CD32)
chr19_-_48867171 0.20 ENST00000377431.2
ENST00000436660.2
ENST00000541566.1
TMEM143
transmembrane protein 143
chr2_-_152118276 0.20 ENST00000409092.1
RBM43
RNA binding motif protein 43
chr20_-_35274548 0.19 ENST00000262866.4
SLA2
Src-like-adaptor 2
chr1_+_32757718 0.19 ENST00000428704.1
HDAC1
histone deacetylase 1
chr19_-_42758040 0.19 ENST00000593944.1
ERF
Ets2 repressor factor
chr10_-_121302195 0.19 ENST00000369103.2
RGS10
regulator of G-protein signaling 10
chr1_+_112016414 0.19 ENST00000343534.5
ENST00000369718.3
C1orf162
chromosome 1 open reading frame 162
chr10_+_106028605 0.18 ENST00000450629.2
GSTO2
glutathione S-transferase omega 2
chr8_-_125551278 0.18 ENST00000519232.1
ENST00000523888.1
ENST00000522810.1
ENST00000519548.1
ENST00000517678.1
ENST00000605953.1
ENST00000276692.6
TATDN1
TatD DNase domain containing 1
chr16_+_57576584 0.18 ENST00000340339.4
GPR114
G protein-coupled receptor 114
chr6_-_34524049 0.18 ENST00000374037.3
SPDEF
SAM pointed domain containing ETS transcription factor
chr15_-_65809581 0.18 ENST00000341861.5
DPP8
dipeptidyl-peptidase 8
chr4_+_76871883 0.18 ENST00000599764.1
AC110615.1
Uncharacterized protein
chr17_-_43487741 0.18 ENST00000455881.1
ARHGAP27
Rho GTPase activating protein 27
chr3_+_14474178 0.18 ENST00000452775.1
SLC6A6
solute carrier family 6 (neurotransmitter transporter), member 6
chr16_+_30960375 0.17 ENST00000318663.4
ENST00000566237.1
ENST00000562699.1
ORAI3
ORAI calcium release-activated calcium modulator 3
chr11_-_46722117 0.17 ENST00000311956.4
ARHGAP1
Rho GTPase activating protein 1
chr1_-_159832438 0.16 ENST00000368100.1
VSIG8
V-set and immunoglobulin domain containing 8
chrX_+_24072833 0.16 ENST00000253039.4
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr12_+_54447637 0.16 ENST00000609810.1
ENST00000430889.2
HOXC4
HOXC4
homeobox C4
Homeobox protein Hox-C4
chr5_+_64859066 0.16 ENST00000261308.5
ENST00000535264.1
ENST00000538977.1
PPWD1
peptidylprolyl isomerase domain and WD repeat containing 1
chr2_-_8723918 0.16 ENST00000454224.1
AC011747.4
AC011747.4
chr11_-_60720002 0.16 ENST00000538739.1
SLC15A3
solute carrier family 15 (oligopeptide transporter), member 3
chr1_+_206138884 0.16 ENST00000341209.5
ENST00000607379.1
FAM72A
family with sequence similarity 72, member A
chr11_-_10920838 0.16 ENST00000503469.2
CTD-2003C8.2
CTD-2003C8.2
chr2_-_180871780 0.16 ENST00000410053.3
ENST00000295749.6
ENST00000404136.2
CWC22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr14_+_75536335 0.16 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr16_-_30381580 0.16 ENST00000409939.3
TBC1D10B
TBC1 domain family, member 10B
chr4_+_95129061 0.16 ENST00000354268.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr10_-_977564 0.16 ENST00000406525.2
LARP4B
La ribonucleoprotein domain family, member 4B
chr11_+_3875757 0.15 ENST00000525403.1
STIM1
stromal interaction molecule 1
chr15_+_91427691 0.15 ENST00000559355.1
ENST00000394302.1
FES
feline sarcoma oncogene
chr15_-_65810042 0.15 ENST00000321147.6
DPP8
dipeptidyl-peptidase 8
chr6_-_144385698 0.15 ENST00000444202.1
ENST00000437412.1
PLAGL1
pleiomorphic adenoma gene-like 1
chr5_+_92919043 0.15 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr7_-_122526499 0.15 ENST00000412584.2
CADPS2
Ca++-dependent secretion activator 2
chr3_-_186080012 0.14 ENST00000544847.1
ENST00000265022.3
DGKG
diacylglycerol kinase, gamma 90kDa
chr17_-_4642429 0.14 ENST00000573123.1
CXCL16
chemokine (C-X-C motif) ligand 16
chr9_-_113800981 0.14 ENST00000538760.1
LPAR1
lysophosphatidic acid receptor 1
chr3_-_20227619 0.13 ENST00000425061.1
ENST00000443724.1
ENST00000421451.1
ENST00000452020.1
ENST00000417364.1
ENST00000306698.2
ENST00000419233.2
ENST00000263753.4
ENST00000383774.1
ENST00000437051.1
ENST00000412868.1
ENST00000429446.3
ENST00000442720.1
SGOL1
shugoshin-like 1 (S. pombe)
chr17_+_76356516 0.13 ENST00000592569.1
RP11-806H10.4
RP11-806H10.4
chr4_-_47916543 0.13 ENST00000507489.1
NFXL1
nuclear transcription factor, X-box binding-like 1
chr8_-_101734308 0.13 ENST00000519004.1
ENST00000519363.1
ENST00000520142.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr12_-_15114603 0.13 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr2_+_233925064 0.13 ENST00000359570.5
ENST00000538935.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr9_-_95640218 0.13 ENST00000395506.3
ENST00000375495.3
ENST00000332591.6
ZNF484
zinc finger protein 484
chr12_-_53901266 0.13 ENST00000609999.1
ENST00000267017.3
NPFF
neuropeptide FF-amide peptide precursor
chr14_+_102276192 0.13 ENST00000557714.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr9_-_14693417 0.13 ENST00000380916.4
ZDHHC21
zinc finger, DHHC-type containing 21
chr6_+_22221010 0.13 ENST00000567753.1
RP11-524C21.2
RP11-524C21.2
chr1_+_173991633 0.13 ENST00000424181.1
RP11-160H22.3
RP11-160H22.3
chr2_+_135011731 0.13 ENST00000281923.2
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr20_+_20033158 0.13 ENST00000340348.6
ENST00000377309.2
ENST00000389656.3
ENST00000377306.1
ENST00000245957.5
ENST00000377303.2
ENST00000475466.1
C20orf26
chromosome 20 open reading frame 26
chr1_-_43282906 0.12 ENST00000372521.4
CCDC23
coiled-coil domain containing 23
chr16_+_70695570 0.12 ENST00000597002.1
FLJ00418
FLJ00418
chr3_-_20227720 0.12 ENST00000412997.1
SGOL1
shugoshin-like 1 (S. pombe)
chr14_-_74416829 0.12 ENST00000534936.1
FAM161B
family with sequence similarity 161, member B
chr19_-_15344243 0.12 ENST00000602233.1
EPHX3
epoxide hydrolase 3
chr1_+_14075865 0.12 ENST00000413440.1
PRDM2
PR domain containing 2, with ZNF domain
chr15_-_45422056 0.12 ENST00000267803.4
ENST00000559014.1
ENST00000558851.1
ENST00000559988.1
ENST00000558996.1
ENST00000558422.1
ENST00000559226.1
ENST00000558326.1
ENST00000558377.1
ENST00000559644.1
DUOXA1
dual oxidase maturation factor 1
chr15_+_59279851 0.12 ENST00000348370.4
ENST00000434298.1
ENST00000559160.1
RNF111
ring finger protein 111
chr1_+_120839412 0.12 ENST00000355228.4
FAM72B
family with sequence similarity 72, member B
chr8_-_37707356 0.12 ENST00000520601.1
ENST00000521170.1
ENST00000220659.6
BRF2
BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
chr6_+_130339710 0.12 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr5_-_40835303 0.12 ENST00000509877.1
ENST00000508493.1
ENST00000274242.5
RPL37
ribosomal protein L37
chr3_-_9291063 0.11 ENST00000383836.3
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr6_-_34524093 0.11 ENST00000544425.1
SPDEF
SAM pointed domain containing ETS transcription factor
chr8_+_104426942 0.11 ENST00000297579.5
DCAF13
DDB1 and CUL4 associated factor 13
chr1_+_179851823 0.11 ENST00000435319.4
TOR1AIP1
torsin A interacting protein 1
chr2_-_153573887 0.11 ENST00000493468.2
ENST00000545856.1
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr3_+_98482159 0.11 ENST00000468553.1
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr4_-_140005443 0.11 ENST00000510408.1
ENST00000420916.2
ENST00000358635.3
ELF2
E74-like factor 2 (ets domain transcription factor)
chr5_+_102455853 0.11 ENST00000515845.1
ENST00000321521.9
ENST00000507921.1
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr11_-_1606513 0.11 ENST00000382171.2
KRTAP5-1
keratin associated protein 5-1
chr20_-_20033052 0.11 ENST00000536226.1
CRNKL1
crooked neck pre-mRNA splicing factor 1
chr17_-_43487780 0.11 ENST00000532038.1
ENST00000528677.1
ARHGAP27
Rho GTPase activating protein 27
chr12_+_32638897 0.11 ENST00000531134.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr3_+_184529929 0.11 ENST00000287546.4
ENST00000437079.3
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr1_-_220445757 0.11 ENST00000358951.2
RAB3GAP2
RAB3 GTPase activating protein subunit 2 (non-catalytic)
chr19_+_10959043 0.11 ENST00000397820.4
C19orf38
chromosome 19 open reading frame 38
chr5_-_10249990 0.11 ENST00000511437.1
ENST00000280330.8
ENST00000510047.1
FAM173B
family with sequence similarity 173, member B
chr5_+_35856951 0.11 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R
interleukin 7 receptor
chr6_+_31126291 0.11 ENST00000376257.3
ENST00000376255.4
TCF19
transcription factor 19
chr17_-_29641104 0.10 ENST00000577894.1
ENST00000330927.4
EVI2B
ecotropic viral integration site 2B
chr15_+_42651691 0.10 ENST00000357568.3
ENST00000349748.3
ENST00000318023.7
ENST00000397163.3
CAPN3
calpain 3, (p94)
chr19_-_18391708 0.10 ENST00000600972.1
JUND
jun D proto-oncogene
chr3_-_28390581 0.10 ENST00000479665.1
AZI2
5-azacytidine induced 2
chr19_-_9420249 0.10 ENST00000591998.1
ZNF699
zinc finger protein 699
chr16_-_30537839 0.10 ENST00000380412.5
ZNF768
zinc finger protein 768
chr1_+_209941827 0.10 ENST00000367023.1
TRAF3IP3
TRAF3 interacting protein 3
chr1_-_20446020 0.10 ENST00000375105.3
PLA2G2D
phospholipase A2, group IID
chr19_+_51728316 0.10 ENST00000436584.2
ENST00000421133.2
ENST00000391796.3
ENST00000262262.4
CD33
CD33 molecule
chr12_-_15114492 0.10 ENST00000541546.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr17_+_72667239 0.10 ENST00000402449.4
RAB37
RAB37, member RAS oncogene family
chr9_-_125675576 0.10 ENST00000373659.3
ZBTB6
zinc finger and BTB domain containing 6
chr12_-_15114191 0.10 ENST00000541380.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr12_-_8218997 0.10 ENST00000307637.4
C3AR1
complement component 3a receptor 1
chr1_+_206138457 0.10 ENST00000367128.3
ENST00000431655.2
FAM72A
family with sequence similarity 72, member A
chr7_-_37488834 0.09 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chr1_+_120839005 0.09 ENST00000369390.3
ENST00000452190.1
FAM72B
family with sequence similarity 72, member B
chr12_-_110939870 0.09 ENST00000447578.2
ENST00000546588.1
ENST00000360579.7
ENST00000549970.1
ENST00000549578.1
VPS29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr5_+_65892174 0.09 ENST00000404260.3
ENST00000403625.2
ENST00000406374.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr19_-_40790729 0.09 ENST00000423127.1
ENST00000583859.1
ENST00000456441.1
ENST00000452077.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr3_-_116163830 0.09 ENST00000333617.4
LSAMP
limbic system-associated membrane protein
chr11_-_61124711 0.09 ENST00000536915.1
CYB561A3
cytochrome b561 family, member A3
chr9_-_130541017 0.09 ENST00000314830.8
SH2D3C
SH2 domain containing 3C
chr1_+_159272111 0.09 ENST00000368114.1
FCER1A
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
chr19_-_4559814 0.09 ENST00000586582.1
SEMA6B
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr2_-_113993020 0.09 ENST00000465084.1
PAX8
paired box 8
chr1_+_151171012 0.09 ENST00000349792.5
ENST00000409426.1
ENST00000441902.2
ENST00000368890.4
ENST00000424999.1
ENST00000368888.4
PIP5K1A
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
chr3_-_155462808 0.09 ENST00000460012.1
PLCH1
phospholipase C, eta 1
chr7_-_150038704 0.09 ENST00000466675.1
ENST00000482669.1
ENST00000467793.1
ENST00000223271.3
RARRES2
retinoic acid receptor responder (tazarotene induced) 2
chr1_+_110158726 0.08 ENST00000531734.1
AMPD2
adenosine monophosphate deaminase 2
chr6_+_31554779 0.08 ENST00000376090.2
LST1
leukocyte specific transcript 1
chr7_+_139528952 0.08 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr3_+_184529948 0.08 ENST00000436792.2
ENST00000446204.2
ENST00000422105.1
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr19_-_42192096 0.08 ENST00000602225.1
CEACAM7
carcinoembryonic antigen-related cell adhesion molecule 7
chr19_+_1383890 0.08 ENST00000539480.1
ENST00000313408.7
ENST00000414651.2
NDUFS7
NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
chr1_+_15783222 0.08 ENST00000359621.4
CELA2A
chymotrypsin-like elastase family, member 2A
chr14_+_102276132 0.08 ENST00000350249.3
ENST00000557621.1
ENST00000556946.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr4_-_102268708 0.08 ENST00000525819.1
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr12_-_120663792 0.08 ENST00000546532.1
ENST00000548912.1
PXN
paxillin
chr4_-_146859787 0.08 ENST00000508784.1
ZNF827
zinc finger protein 827
chr15_+_43985084 0.08 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr4_+_86525299 0.08 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr8_+_27632083 0.08 ENST00000519637.1
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr12_+_49717019 0.08 ENST00000549275.1
ENST00000551245.1
ENST00000380327.5
ENST00000548311.1
ENST00000550346.1
ENST00000550709.1
ENST00000549534.1
ENST00000257909.3
TROAP
trophinin associated protein
chrX_+_24073048 0.08 ENST00000423068.1
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr14_-_50319482 0.08 ENST00000546046.1
ENST00000555970.1
ENST00000554626.1
ENST00000545773.1
ENST00000556672.1
NEMF
nuclear export mediator factor
chr17_-_56492989 0.08 ENST00000583753.1
RNF43
ring finger protein 43
chr15_+_43885252 0.08 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr1_-_175161890 0.07 ENST00000545251.2
ENST00000423313.1
KIAA0040
KIAA0040
chr1_+_161551101 0.07 ENST00000367962.4
ENST00000367960.5
ENST00000403078.3
ENST00000428605.2
FCGR2B
Fc fragment of IgG, low affinity IIb, receptor (CD32)
chr14_+_96968802 0.07 ENST00000556619.1
ENST00000392990.2
PAPOLA
poly(A) polymerase alpha
chr10_+_18429671 0.07 ENST00000282343.8
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr14_+_75536280 0.07 ENST00000238686.8
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr3_-_195603566 0.07 ENST00000424563.1
ENST00000411741.1
TNK2
tyrosine kinase, non-receptor, 2
chrX_+_24167746 0.07 ENST00000428571.1
ENST00000539115.1
ZFX
zinc finger protein, X-linked
chr11_-_18656028 0.07 ENST00000336349.5
SPTY2D1
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr14_+_102276209 0.07 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr6_-_110012380 0.07 ENST00000424296.2
ENST00000341338.6
ENST00000368948.2
ENST00000285397.5
AK9
adenylate kinase 9
chr16_+_31213206 0.07 ENST00000561916.2
C16orf98
chromosome 16 open reading frame 98
chr2_+_162087577 0.07 ENST00000439442.1
TANK
TRAF family member-associated NFKB activator
chr14_+_45431379 0.07 ENST00000361577.3
ENST00000361462.2
ENST00000382233.2
FAM179B
family with sequence similarity 179, member B
chr2_-_26101314 0.07 ENST00000336112.4
ENST00000272341.4
ASXL2
additional sex combs like 2 (Drosophila)
chr14_-_50319758 0.07 ENST00000298310.5
NEMF
nuclear export mediator factor
chr2_+_102758271 0.07 ENST00000428279.1
IL1R1
interleukin 1 receptor, type I
chr14_-_98444461 0.07 ENST00000499006.2
C14orf64
chromosome 14 open reading frame 64
chr12_+_10124001 0.07 ENST00000396507.3
ENST00000304361.4
ENST00000434319.2
CLEC12A
C-type lectin domain family 12, member A
chr19_+_2476116 0.07 ENST00000215631.4
ENST00000587345.1
GADD45B
growth arrest and DNA-damage-inducible, beta
chr5_+_159848854 0.07 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
PTTG1
pituitary tumor-transforming 1
chr3_-_176914238 0.07 ENST00000430069.1
ENST00000428970.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr1_-_45956822 0.07 ENST00000372086.3
ENST00000341771.6
TESK2
testis-specific kinase 2
chr2_-_152830479 0.07 ENST00000360283.6
CACNB4
calcium channel, voltage-dependent, beta 4 subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of SPIB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0031296 B cell costimulation(GO:0031296)
0.1 0.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.3 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.3 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.5 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.1 0.2 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.3 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.3 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.3 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.0 0.2 GO:0016068 regulation of type I hypersensitivity(GO:0001810) type I hypersensitivity(GO:0016068)
0.0 0.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.5 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.3 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.4 GO:0090487 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.0 0.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0 0.7 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.1 GO:0019732 antifungal humoral response(GO:0019732)
0.0 0.2 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.5 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0045404 positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.3 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.0 GO:0002461 tolerance induction dependent upon immune response(GO:0002461)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0061566 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.0 0.1 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.0 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.0 0.0 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.0 GO:0045399 positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.6 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0042335 cuticle development(GO:0042335)
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.0 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.3 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.0 0.2 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.4 GO:0033263 CORVET complex(GO:0033263)
0.0 0.2 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.1 GO:0036457 keratohyalin granule(GO:0036457)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1 0.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.2 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 0.4 GO:0045174 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.1 0.5 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.3 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.1 0.5 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.3 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.3 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.0 0.1 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 0.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.0 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0052811 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.1 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.1 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0 0.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation