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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for TBP

Z-value: 3.24

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Transcription factors associated with TBP

Gene Symbol Gene ID Gene Info
TBP
ENSG00000112592.8 TATA-box binding protein

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBPhg19_v2_chr6_+_170863421_170863484-0.831.7e-01Click!

Activity profile of TBP motif

Sorted Z-values of TBP motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_91087651 4.65 ENST00000371818.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr15_+_45722727 4.48 ENST00000396650.2
ENST00000558435.1
ENST00000344300.3
C15orf48
chromosome 15 open reading frame 48
chr1_+_153330322 4.30 ENST00000368738.3
S100A9
S100 calcium binding protein A9
chr12_-_121477039 4.07 ENST00000257570.5
OASL
2'-5'-oligoadenylate synthetase-like
chr12_-_121476959 3.84 ENST00000339275.5
OASL
2'-5'-oligoadenylate synthetase-like
chr10_+_91152303 3.82 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr11_+_57308979 3.67 ENST00000457912.1
SMTNL1
smoothelin-like 1
chr9_-_21077939 3.52 ENST00000380232.2
IFNB1
interferon, beta 1, fibroblast
chr11_-_615570 3.51 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chr7_-_92777606 2.97 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr17_-_34207295 2.80 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr8_-_23261589 2.76 ENST00000524168.1
ENST00000523833.2
ENST00000519243.1
ENST00000389131.3
LOXL2
lysyl oxidase-like 2
chr5_+_53686658 2.25 ENST00000512618.1
LINC01033
long intergenic non-protein coding RNA 1033
chr11_-_2950642 2.22 ENST00000314222.4
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr1_-_228613026 2.10 ENST00000366696.1
HIST3H3
histone cluster 3, H3
chr11_+_18287801 1.99 ENST00000532858.1
ENST00000405158.2
SAA1
serum amyloid A1
chr19_+_10381769 1.93 ENST00000423829.2
ENST00000588645.1
ICAM1
intercellular adhesion molecule 1
chr7_-_134143841 1.83 ENST00000285930.4
AKR1B1
aldo-keto reductase family 1, member B1 (aldose reductase)
chr11_-_18270182 1.80 ENST00000528349.1
ENST00000526900.1
ENST00000529528.1
ENST00000414546.2
ENST00000256733.4
SAA2
serum amyloid A2
chr12_+_13044787 1.75 ENST00000534831.1
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr11_+_18287721 1.73 ENST00000356524.4
SAA1
serum amyloid A1
chr9_-_35658007 1.62 ENST00000602361.1
RMRP
RNA component of mitochondrial RNA processing endoribonuclease
chr17_+_80186908 1.55 ENST00000582743.1
ENST00000578684.1
ENST00000577650.1
ENST00000582715.1
SLC16A3
solute carrier family 16 (monocarboxylate transporter), member 3
chr6_-_26124138 1.55 ENST00000314332.5
ENST00000396984.1
HIST1H2BC
histone cluster 1, H2bc
chr8_+_145321517 1.48 ENST00000340210.1
SCXB
scleraxis homolog B (mouse)
chr12_+_52695617 1.43 ENST00000293525.5
KRT86
keratin 86
chr6_+_27114861 1.40 ENST00000377459.1
HIST1H2AH
histone cluster 1, H2ah
chr1_-_935491 1.39 ENST00000304952.6
HES4
hes family bHLH transcription factor 4
chr19_-_6720686 1.37 ENST00000245907.6
C3
complement component 3
chr18_-_61329118 1.37 ENST00000332821.8
ENST00000283752.5
SERPINB3
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr12_-_52685312 1.36 ENST00000327741.5
KRT81
keratin 81
chr11_+_61735266 1.35 ENST00000601917.1
AP003733.1
Uncharacterized protein; cDNA FLJ36460 fis, clone THYMU2014801
chr11_-_61735103 1.35 ENST00000529191.1
ENST00000529631.1
ENST00000530019.1
ENST00000529548.1
ENST00000273550.7
FTH1
ferritin, heavy polypeptide 1
chr21_-_43786634 1.31 ENST00000291527.2
TFF1
trefoil factor 1
chr1_-_156675368 1.28 ENST00000368222.3
CRABP2
cellular retinoic acid binding protein 2
chr11_-_61735029 1.28 ENST00000526640.1
FTH1
ferritin, heavy polypeptide 1
chr16_+_2014941 1.27 ENST00000531523.1
SNHG9
small nucleolar RNA host gene 9 (non-protein coding)
chr19_+_36347787 1.24 ENST00000347900.6
ENST00000360202.5
KIRREL2
kin of IRRE like 2 (Drosophila)
chr6_-_26250835 1.24 ENST00000446824.2
HIST1H3F
histone cluster 1, H3f
chr16_+_56691606 1.23 ENST00000334350.6
MT1F
metallothionein 1F
chr14_+_65007177 1.23 ENST00000247207.6
HSPA2
heat shock 70kDa protein 2
chr11_+_43964055 1.23 ENST00000528572.1
C11orf96
chromosome 11 open reading frame 96
chr20_+_9049303 1.22 ENST00000407043.2
ENST00000441846.1
PLCB4
phospholipase C, beta 4
chr5_-_27038683 1.22 ENST00000511822.1
ENST00000231021.4
CDH9
cadherin 9, type 2 (T1-cadherin)
chr11_-_61734599 1.20 ENST00000532601.1
FTH1
ferritin, heavy polypeptide 1
chr16_-_67965756 1.20 ENST00000571044.1
ENST00000571605.1
CTRL
chymotrypsin-like
chr20_-_23731893 1.20 ENST00000398402.1
CST1
cystatin SN
chr3_-_170588163 1.17 ENST00000295830.8
RPL22L1
ribosomal protein L22-like 1
chr8_-_124553437 1.17 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chr2_+_33661382 1.16 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr8_+_145490549 1.15 ENST00000340695.2
SCXA
scleraxis homolog A (mouse)
chr17_-_39183452 1.15 ENST00000361883.5
KRTAP1-5
keratin associated protein 1-5
chr1_+_37940153 1.13 ENST00000373087.6
ZC3H12A
zinc finger CCCH-type containing 12A
chr1_-_11918988 1.09 ENST00000376468.3
NPPB
natriuretic peptide B
chr1_+_17575584 1.08 ENST00000375460.3
PADI3
peptidyl arginine deiminase, type III
chr1_-_935361 1.06 ENST00000484667.2
HES4
hes family bHLH transcription factor 4
chr6_-_27860956 1.06 ENST00000359611.2
HIST1H2AM
histone cluster 1, H2am
chr8_-_6735451 1.05 ENST00000297439.3
DEFB1
defensin, beta 1
chr7_-_41742697 1.04 ENST00000242208.4
INHBA
inhibin, beta A
chr6_-_27835357 1.03 ENST00000331442.3
HIST1H1B
histone cluster 1, H1b
chr15_+_76629064 1.00 ENST00000290759.4
ISL2
ISL LIM homeobox 2
chr6_+_26156551 1.00 ENST00000304218.3
HIST1H1E
histone cluster 1, H1e
chr12_+_40787194 0.99 ENST00000425730.2
ENST00000454784.4
MUC19
mucin 19, oligomeric
chr3_+_101546827 0.99 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr19_-_53238260 0.99 ENST00000453741.2
ENST00000602162.1
ENST00000601643.1
ENST00000596702.1
ENST00000600943.1
ENST00000543227.1
ENST00000540744.1
ZNF611
zinc finger protein 611
chr8_-_6914251 0.97 ENST00000330590.2
DEFA5
defensin, alpha 5, Paneth cell-specific
chr19_+_46732988 0.96 ENST00000437936.1
IGFL1
IGF-like family member 1
chr19_+_8386371 0.96 ENST00000600659.2
RPS28
ribosomal protein S28
chr3_+_173116225 0.95 ENST00000457714.1
NLGN1
neuroligin 1
chr1_-_156675564 0.95 ENST00000368220.1
CRABP2
cellular retinoic acid binding protein 2
chr3_-_139195350 0.95 ENST00000232217.2
RBP2
retinol binding protein 2, cellular
chr11_+_71276609 0.95 ENST00000398531.1
ENST00000376536.4
KRTAP5-10
keratin associated protein 5-10
chr5_-_104728663 0.94 ENST00000503650.1
RP11-6N13.1
RP11-6N13.1
chrX_-_133792480 0.93 ENST00000359237.4
PLAC1
placenta-specific 1
chr17_+_77021702 0.93 ENST00000392445.2
ENST00000354124.3
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr19_-_12912601 0.93 ENST00000334482.5
PRDX2
peroxiredoxin 2
chr6_-_26043885 0.92 ENST00000357905.2
HIST1H2BB
histone cluster 1, H2bb
chr17_-_39674668 0.92 ENST00000393981.3
KRT15
keratin 15
chr8_-_16859690 0.91 ENST00000180166.5
FGF20
fibroblast growth factor 20
chr17_+_40458130 0.90 ENST00000587646.1
STAT5A
signal transducer and activator of transcription 5A
chr16_+_56691911 0.90 ENST00000568475.1
MT1F
metallothionein 1F
chr6_+_71104588 0.89 ENST00000418403.1
RP11-462G2.1
RP11-462G2.1
chr2_-_239148599 0.88 ENST00000409182.1
ENST00000409002.3
ENST00000450098.1
ENST00000409356.1
ENST00000409160.3
ENST00000409574.1
ENST00000272937.5
HES6
hes family bHLH transcription factor 6
chr6_-_133035185 0.88 ENST00000367928.4
VNN1
vanin 1
chr6_+_26217159 0.88 ENST00000303910.2
HIST1H2AE
histone cluster 1, H2ae
chr11_+_61129456 0.88 ENST00000278826.6
TMEM138
transmembrane protein 138
chr1_-_23886285 0.87 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr14_-_73997901 0.86 ENST00000557603.1
ENST00000556455.1
HEATR4
HEAT repeat containing 4
chr22_+_39916558 0.86 ENST00000337304.2
ENST00000396680.1
ATF4
activating transcription factor 4
chr1_-_156675535 0.86 ENST00000368221.1
CRABP2
cellular retinoic acid binding protein 2
chr21_-_43735628 0.85 ENST00000291525.10
ENST00000518498.1
TFF3
trefoil factor 3 (intestinal)
chr19_-_33793430 0.83 ENST00000498907.2
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr7_+_116593536 0.81 ENST00000417919.1
ST7
suppression of tumorigenicity 7
chr19_+_2269485 0.81 ENST00000582888.4
ENST00000602676.2
ENST00000322297.4
ENST00000583542.4
OAZ1
ornithine decarboxylase antizyme 1
chr7_-_7575477 0.81 ENST00000399429.3
COL28A1
collagen, type XXVIII, alpha 1
chr18_+_34124507 0.80 ENST00000591635.1
FHOD3
formin homology 2 domain containing 3
chr3_-_129035120 0.80 ENST00000333762.4
H1FX
H1 histone family, member X
chr12_+_27623565 0.79 ENST00000535986.1
SMCO2
single-pass membrane protein with coiled-coil domains 2
chr12_-_125398850 0.77 ENST00000535859.1
ENST00000546271.1
ENST00000540700.1
ENST00000546120.1
UBC
ubiquitin C
chr19_-_12912657 0.77 ENST00000301522.2
PRDX2
peroxiredoxin 2
chr7_+_75931861 0.77 ENST00000248553.6
HSPB1
heat shock 27kDa protein 1
chr1_+_41448820 0.76 ENST00000372616.1
CTPS1
CTP synthase 1
chr2_-_75426826 0.75 ENST00000305249.5
TACR1
tachykinin receptor 1
chr11_-_64646086 0.75 ENST00000320631.3
EHD1
EH-domain containing 1
chr18_+_9102669 0.74 ENST00000497577.2
NDUFV2
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr15_-_62457480 0.74 ENST00000380392.3
C2CD4B
C2 calcium-dependent domain containing 4B
chr17_-_38928414 0.73 ENST00000335552.4
KRT26
keratin 26
chr9_+_130911723 0.73 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2
lipocalin 2
chr2_-_99917639 0.71 ENST00000308528.4
LYG1
lysozyme G-like 1
chr9_+_130911770 0.71 ENST00000372998.1
LCN2
lipocalin 2
chr12_-_11036844 0.70 ENST00000428168.2
PRH1
proline-rich protein HaeIII subfamily 1
chr7_+_129015484 0.69 ENST00000490911.1
AHCYL2
adenosylhomocysteinase-like 2
chr17_+_16284399 0.69 ENST00000535788.1
UBB
ubiquitin B
chr19_+_18118972 0.69 ENST00000593560.2
ENST00000222250.4
ARRDC2
arrestin domain containing 2
chr20_+_30193083 0.69 ENST00000376112.3
ENST00000376105.3
ID1
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
chr2_-_182545603 0.69 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr10_-_95209 0.69 ENST00000332708.5
ENST00000309812.4
TUBB8
tubulin, beta 8 class VIII
chr6_+_31783291 0.69 ENST00000375651.5
ENST00000608703.1
ENST00000458062.2
HSPA1A
heat shock 70kDa protein 1A
chr17_-_48546324 0.68 ENST00000508540.1
CHAD
chondroadherin
chr12_-_125399573 0.67 ENST00000339647.5
UBC
ubiquitin C
chr2_+_85132749 0.67 ENST00000233143.4
TMSB10
thymosin beta 10
chr2_+_65663812 0.67 ENST00000606978.1
ENST00000377977.3
ENST00000536804.1
AC074391.1
AC074391.1
chr17_+_16284104 0.67 ENST00000577958.1
ENST00000302182.3
ENST00000577640.1
UBB
ubiquitin B
chr6_-_2903514 0.67 ENST00000380698.4
SERPINB9
serpin peptidase inhibitor, clade B (ovalbumin), member 9
chr8_-_56987057 0.67 ENST00000518875.1
RPS20
ribosomal protein S20
chr6_-_30585009 0.66 ENST00000376511.2
PPP1R10
protein phosphatase 1, regulatory subunit 10
chr1_-_149812765 0.65 ENST00000369158.1
HIST2H3C
histone cluster 2, H3c
chrX_-_48814810 0.65 ENST00000376488.3
ENST00000396743.3
ENST00000156084.4
OTUD5
OTU domain containing 5
chr3_+_57882061 0.65 ENST00000461354.1
ENST00000466255.1
SLMAP
sarcolemma associated protein
chr12_+_6309517 0.64 ENST00000382519.4
ENST00000009180.4
CD9
CD9 molecule
chr11_-_9025541 0.63 ENST00000525100.1
ENST00000309166.3
ENST00000531090.1
NRIP3
nuclear receptor interacting protein 3
chr12_+_130646999 0.62 ENST00000539839.1
ENST00000229030.4
FZD10
frizzled family receptor 10
chr1_+_144339738 0.62 ENST00000538264.1
AL592284.1
Protein LOC642441
chr1_-_153363452 0.62 ENST00000368732.1
ENST00000368733.3
S100A8
S100 calcium binding protein A8
chr6_-_134495992 0.62 ENST00000475719.2
ENST00000367857.5
ENST00000237305.7
SGK1
serum/glucocorticoid regulated kinase 1
chr11_+_63304273 0.62 ENST00000439013.2
ENST00000255688.3
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr15_-_41166414 0.61 ENST00000220507.4
RHOV
ras homolog family member V
chr7_-_3214287 0.61 ENST00000404626.3
AC091801.1
LOC392621; Uncharacterized protein
chr1_+_55446465 0.61 ENST00000371268.3
TMEM61
transmembrane protein 61
chr4_+_74735102 0.61 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr13_+_46786051 0.60 ENST00000446175.1
LRRC63
leucine rich repeat containing 63
chr3_-_99595037 0.60 ENST00000383694.2
FILIP1L
filamin A interacting protein 1-like
chr8_-_145754428 0.60 ENST00000527462.1
ENST00000313465.5
ENST00000524821.1
C8orf82
chromosome 8 open reading frame 82
chrX_-_48931648 0.60 ENST00000376386.3
ENST00000376390.4
PRAF2
PRA1 domain family, member 2
chr1_-_95007193 0.59 ENST00000370207.4
ENST00000334047.7
F3
coagulation factor III (thromboplastin, tissue factor)
chr6_-_26033796 0.59 ENST00000259791.2
HIST1H2AB
histone cluster 1, H2ab
chr2_-_106054952 0.59 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
FHL2
four and a half LIM domains 2
chr17_+_76183432 0.59 ENST00000591256.1
ENST00000589256.1
ENST00000588800.1
ENST00000591952.1
ENST00000327898.5
ENST00000586542.1
ENST00000586731.1
AFMID
arylformamidase
chr2_+_40973618 0.58 ENST00000420187.1
AC007317.1
AC007317.1
chr1_-_89488510 0.58 ENST00000564665.1
ENST00000370481.4
GBP3
guanylate binding protein 3
chr17_+_32646055 0.58 ENST00000394620.1
CCL8
chemokine (C-C motif) ligand 8
chr7_+_73097890 0.58 ENST00000265758.2
ENST00000423166.2
ENST00000423497.1
WBSCR22
Williams Beuren syndrome chromosome region 22
chr2_+_39893043 0.58 ENST00000281961.2
TMEM178A
transmembrane protein 178A
chr3_+_70048881 0.57 ENST00000483525.1
RP11-460N16.1
RP11-460N16.1
chr18_+_29598335 0.57 ENST00000217740.3
RNF125
ring finger protein 125, E3 ubiquitin protein ligase
chr7_+_107301065 0.57 ENST00000265715.3
SLC26A4
solute carrier family 26 (anion exchanger), member 4
chr19_-_55919087 0.56 ENST00000587845.1
ENST00000589978.1
ENST00000264552.9
UBE2S
ubiquitin-conjugating enzyme E2S
chr1_-_45987526 0.56 ENST00000372079.1
ENST00000262746.1
ENST00000447184.1
ENST00000319248.8
PRDX1
peroxiredoxin 1
chr7_+_116593292 0.56 ENST00000393446.2
ENST00000265437.5
ENST00000393451.3
ST7
suppression of tumorigenicity 7
chr5_-_153857819 0.55 ENST00000231121.2
HAND1
heart and neural crest derivatives expressed 1
chrX_+_140677562 0.54 ENST00000370518.3
SPANXA2
SPANX family, member A2
chr10_+_5135981 0.54 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr16_+_82068873 0.53 ENST00000566213.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr6_+_32940436 0.53 ENST00000395287.1
BRD2
bromodomain containing 2
chr7_+_75024337 0.53 ENST00000450434.1
TRIM73
tripartite motif containing 73
chr5_-_180671172 0.52 ENST00000512805.1
GNB2L1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr7_-_73097741 0.52 ENST00000395176.2
DNAJC30
DnaJ (Hsp40) homolog, subfamily C, member 30
chr13_-_103719196 0.52 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr7_+_44836276 0.51 ENST00000451562.1
ENST00000468812.1
ENST00000489459.1
ENST00000355968.6
PPIA
peptidylprolyl isomerase A (cyclophilin A)
chr17_+_7184986 0.51 ENST00000317370.8
ENST00000571308.1
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chr5_-_55412774 0.51 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr17_+_16284604 0.51 ENST00000395839.1
ENST00000395837.1
UBB
ubiquitin B
chr8_+_1993152 0.50 ENST00000262113.4
MYOM2
myomesin 2
chr2_+_169923577 0.50 ENST00000432060.2
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr8_+_79503458 0.50 ENST00000518467.1
PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr5_-_54468974 0.49 ENST00000381375.2
ENST00000296733.1
ENST00000322374.6
ENST00000334206.5
ENST00000331730.3
CDC20B
cell division cycle 20B
chr9_+_35658262 0.49 ENST00000378407.3
ENST00000378406.1
ENST00000426546.2
ENST00000327351.2
ENST00000421582.2
CCDC107
coiled-coil domain containing 107
chr6_+_46761118 0.49 ENST00000230588.4
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr4_+_74606223 0.47 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr19_+_572543 0.47 ENST00000333511.3
ENST00000573216.1
ENST00000353555.4
BSG
basigin (Ok blood group)
chr18_-_47018869 0.47 ENST00000583036.1
ENST00000580261.1
RPL17
ribosomal protein L17
chr11_-_62432641 0.47 ENST00000528405.1
ENST00000524958.1
ENST00000525675.1
RP11-831H9.11
C11orf48
Uncharacterized protein
chromosome 11 open reading frame 48
chr4_+_74702214 0.47 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr20_+_18488528 0.47 ENST00000377465.1
SEC23B
Sec23 homolog B (S. cerevisiae)
chr5_-_54988559 0.47 ENST00000502247.1
SLC38A9
solute carrier family 38, member 9
chr1_+_89829610 0.46 ENST00000370456.4
ENST00000535065.1
GBP6
guanylate binding protein family, member 6
chr1_-_89641680 0.46 ENST00000294671.2
GBP7
guanylate binding protein 7
chr7_-_122339162 0.46 ENST00000340112.2
RNF133
ring finger protein 133
chr18_+_616711 0.46 ENST00000579494.1
CLUL1
clusterin-like 1 (retinal)
chr8_-_73793975 0.46 ENST00000523881.1
RP11-1145L24.1
RP11-1145L24.1
chr13_+_53602894 0.46 ENST00000219022.2
OLFM4
olfactomedin 4
chr18_-_47018769 0.46 ENST00000583637.1
ENST00000578528.1
ENST00000578532.1
ENST00000580387.1
ENST00000579248.1
ENST00000581373.1
RPL17
ribosomal protein L17
chr16_+_56703703 0.46 ENST00000332374.4
MT1H
metallothionein 1H
chr20_+_43835638 0.45 ENST00000372781.3
ENST00000244069.6
SEMG1
semenogelin I
chr15_-_63674218 0.45 ENST00000178638.3
CA12
carbonic anhydrase XII
chr17_-_39203519 0.45 ENST00000542137.1
ENST00000391419.3
KRTAP2-1
keratin associated protein 2-1
chr6_+_159291090 0.44 ENST00000367073.4
ENST00000608817.1
C6orf99
chromosome 6 open reading frame 99
chr11_+_47293795 0.43 ENST00000422579.1
MADD
MAP-kinase activating death domain
chr5_+_43033818 0.43 ENST00000607830.1
CTD-2035E11.4
CTD-2035E11.4
chr22_-_40929812 0.42 ENST00000422851.1
MKL1
megakaryoblastic leukemia (translocation) 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TBP

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.3 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
1.5 4.5 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
1.0 3.8 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.7 2.8 GO:0018277 protein deamination(GO:0018277)
0.6 1.8 GO:0006059 hexitol metabolic process(GO:0006059)
0.6 3.5 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.5 1.4 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.4 3.2 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.4 1.1 GO:2000625 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.3 1.0 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.3 1.0 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.3 1.4 GO:0035425 autocrine signaling(GO:0035425)
0.3 4.6 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.3 1.9 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.3 1.0 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.3 1.4 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.3 0.9 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.3 2.0 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.3 1.0 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.2 0.7 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.2 0.7 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.2 0.7 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.2 0.2 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.2 4.5 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.2 0.7 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.2 1.6 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.2 1.1 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.2 3.0 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 0.6 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.2 1.0 GO:0010193 response to ozone(GO:0010193) positive regulation of saliva secretion(GO:0046878)
0.2 0.8 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.2 0.2 GO:0060460 left lung morphogenesis(GO:0060460)
0.2 0.5 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.2 0.9 GO:0000255 allantoin metabolic process(GO:0000255)
0.2 0.7 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.2 0.8 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.2 0.9 GO:0006776 vitamin A metabolic process(GO:0006776)
0.2 0.8 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.4 GO:1902573 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.1 1.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.4 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.1 0.6 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.7 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.1 0.5 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.1 0.4 GO:0044691 tooth eruption(GO:0044691)
0.1 1.3 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.4 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.1 0.6 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 0.7 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 0.4 GO:0040010 positive regulation of growth rate(GO:0040010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.1 0.9 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.8 GO:0060356 leucine import(GO:0060356)
0.1 0.5 GO:0060324 face development(GO:0060324) face morphogenesis(GO:0060325)
0.1 0.6 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.6 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 3.3 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 4.1 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.1 3.2 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.1 0.3 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 0.3 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 0.7 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 2.0 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.4 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 1.6 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.1 0.7 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 1.0 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.1 0.4 GO:0038042 dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 1.3 GO:0046218 tryptophan catabolic process(GO:0006569) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.1 0.2 GO:1900738 dense core granule biogenesis(GO:0061110) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.1 3.5 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.1 0.3 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 8.2 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 0.2 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.1 1.6 GO:0002544 chronic inflammatory response(GO:0002544)
0.1 1.4 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 0.5 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 1.1 GO:0035810 positive regulation of urine volume(GO:0035810)
0.1 0.3 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.6 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 1.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.8 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 1.0 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 1.6 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 0.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.1 1.2 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.4 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.6 GO:0030913 paranodal junction assembly(GO:0030913)
0.1 0.2 GO:0014870 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870)
0.1 0.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.4 GO:0097319 fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.1 0.2 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 1.6 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 0.3 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1 0.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.4 GO:1904796 regulation of core promoter binding(GO:1904796) positive regulation of core promoter binding(GO:1904798)
0.1 2.1 GO:0032460 negative regulation of protein oligomerization(GO:0032460)
0.1 0.6 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.6 GO:0015705 iodide transport(GO:0015705)
0.0 0.4 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 1.0 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.5 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.5 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.8 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.3 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.0 0.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.2 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.2 GO:0006642 triglyceride mobilization(GO:0006642) response to selenium ion(GO:0010269)
0.0 2.1 GO:0006953 acute-phase response(GO:0006953)
0.0 0.6 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.3 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.2 GO:0039533 regulation of MDA-5 signaling pathway(GO:0039533) positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 1.1 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.4 GO:0060347 heart trabecula formation(GO:0060347)
0.0 1.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.9 GO:0030903 notochord development(GO:0030903)
0.0 4.4 GO:0070268 cornification(GO:0070268)
0.0 0.6 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.3 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0060017 parathyroid gland development(GO:0060017)
0.0 1.2 GO:0016042 lipid catabolic process(GO:0016042)
0.0 0.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.3 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
0.0 0.4 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.5 GO:0046697 decidualization(GO:0046697)
0.0 0.6 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.0 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.0 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 2.0 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.0 0.7 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.6 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.6 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.2 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 2.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.6 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.2 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.5 GO:0031424 keratinization(GO:0031424)
0.0 0.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 0.0 GO:1903413 response to bile acid(GO:1903412) cellular response to bile acid(GO:1903413)
0.0 0.1 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.2 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.0 0.8 GO:0006338 chromatin remodeling(GO:0006338)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.4 1.8 GO:0097454 Schwann cell microvillus(GO:0097454)
0.3 1.0 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 1.2 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.2 2.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 1.9 GO:0072687 meiotic spindle(GO:0072687)
0.2 1.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.9 GO:1990037 Lewy body core(GO:1990037)
0.1 0.4 GO:0070702 inner mucus layer(GO:0070702) outer mucus layer(GO:0070703)
0.1 3.9 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.7 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 0.2 GO:0036457 keratohyalin granule(GO:0036457)
0.1 1.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 5.9 GO:0031430 M band(GO:0031430)
0.1 3.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 1.3 GO:0032433 filopodium tip(GO:0032433)
0.1 4.5 GO:0045095 keratin filament(GO:0045095)
0.1 0.2 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 0.2 GO:1990745 EARP complex(GO:1990745)
0.1 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.0 GO:0097225 sperm midpiece(GO:0097225)
0.1 2.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 1.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.7 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 3.6 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.4 GO:0005610 laminin-5 complex(GO:0005610)
0.0 2.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.5 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.3 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 3.0 GO:0018995 host(GO:0018995) host cell(GO:0043657)
0.0 1.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0000243 commitment complex(GO:0000243)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.8 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.7 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.2 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 2.9 GO:0005604 basement membrane(GO:0005604)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.6 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0032982 myosin filament(GO:0032982)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.9 GO:0001772 immunological synapse(GO:0001772)
0.0 0.5 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 5.5 GO:0034774 secretory granule lumen(GO:0034774)
0.0 0.7 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.1 GO:0001939 female pronucleus(GO:0001939)
0.0 0.4 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.6 GO:0031526 brush border membrane(GO:0031526)
0.0 0.8 GO:1904115 axon cytoplasm(GO:1904115)
0.0 1.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 1.4 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.9 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.7 3.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.7 7.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.6 3.0 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.3 3.8 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 2.8 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 0.9 GO:0004995 tachykinin receptor activity(GO:0004995)
0.2 1.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.2 2.4 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2 1.0 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 4.0 GO:0019841 retinol binding(GO:0019841)
0.2 1.2 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.2 0.8 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.2 1.8 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.2 0.8 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.2 0.6 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.2 0.8 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.9 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.4 GO:0086040 sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086040)
0.1 1.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.4 GO:0031768 growth hormone-releasing hormone activity(GO:0016608) ghrelin receptor binding(GO:0031768)
0.1 0.9 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 2.2 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.4 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.9 GO:0046790 virion binding(GO:0046790)
0.1 0.4 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.7 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.3 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.1 4.8 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.6 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 0.6 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.7 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.6 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.7 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.2 GO:0070697 activin receptor binding(GO:0070697)
0.1 0.5 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.3 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 0.4 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 1.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.3 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 1.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.1 GO:0035198 miRNA binding(GO:0035198)
0.0 1.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 1.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 2.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.3 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 1.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.2 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 3.3 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.6 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.6 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 1.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.7 GO:0070628 proteasome binding(GO:0070628)
0.0 0.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.4 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 4.1 GO:0002020 protease binding(GO:0002020)
0.0 0.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.6 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.4 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.4 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 0.9 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.7 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 3.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 4.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.0 GO:0019960 C-X3-C chemokine receptor activity(GO:0016495) C-X3-C chemokine binding(GO:0019960)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.3 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.0 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.2 8.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.2 PID FOXO PATHWAY FoxO family signaling
0.1 0.6 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 3.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 3.3 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.9 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 2.0 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.8 PID AURORA A PATHWAY Aurora A signaling
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.6 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.9 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.3 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 2.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 2.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 PID IL23 PATHWAY IL23-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.0 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.2 2.0 REACTOME DEFENSINS Genes involved in Defensins
0.2 16.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 0.5 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 3.7 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 5.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.0 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.8 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 1.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.8 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 2.8 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 0.9 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 1.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 0.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 2.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 2.6 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.9 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 2.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 1.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.6 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.6 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.2 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)